LOCUS       DASHWW010000001       155597 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.001, whole genome shotgun sequence.
ACCESSION   DASHWW010000001 DASHWW010000000
VERSION     DASHWW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 155597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 155597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..155597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.001"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            293..1480
                     /locus_tag="U2R64_000001"
     CDS             293..1480
                     /locus_tag="U2R64_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEM8916859.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            complement(1612..3798)
                     /locus_tag="U2R64_000002"
     CDS             complement(1612..3798)
                     /locus_tag="U2R64_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEM8916860.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            4016..4699
                     /locus_tag="U2R64_000003"
     CDS             4016..4699
                     /locus_tag="U2R64_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEM8916861.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            complement(4780..5499)
                     /locus_tag="U2R64_000004"
     CDS             complement(4780..5499)
                     /locus_tag="U2R64_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEM8916862.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(5811..6017)
                     /locus_tag="U2R64_000005"
     CDS             complement(5811..6017)
                     /locus_tag="U2R64_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916863.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            6262..6864
                     /locus_tag="U2R64_000006"
     CDS             6262..6864
                     /locus_tag="U2R64_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEM8916864.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            7005..8285
                     /locus_tag="U2R64_000007"
     CDS             7005..8285
                     /locus_tag="U2R64_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEM8916865.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            8298..9026
                     /locus_tag="U2R64_000008"
     CDS             8298..9026
                     /locus_tag="U2R64_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8916866.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(9095..10618)
                     /locus_tag="U2R64_000009"
     CDS             complement(9095..10618)
                     /locus_tag="U2R64_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEM8916867.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            10870..12051
                     /locus_tag="U2R64_000010"
     CDS             10870..12051
                     /locus_tag="U2R64_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8916868.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(12111..13739)
                     /gene="treC"
                     /locus_tag="U2R64_000011"
     CDS             complement(12111..13739)
                     /gene="treC"
                     /locus_tag="U2R64_000011"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEM8916869.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(14190..16901)
                     /locus_tag="U2R64_000012"
     CDS             complement(14190..16901)
                     /locus_tag="U2R64_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8916870.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(16911..17612)
                     /locus_tag="U2R64_000013"
     CDS             complement(16911..17612)
                     /locus_tag="U2R64_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8916871.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            17798..18397
                     /locus_tag="U2R64_000014"
     CDS             17798..18397
                     /locus_tag="U2R64_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8916872.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            18478..19491
                     /locus_tag="U2R64_000015"
     CDS             18478..19491
                     /locus_tag="U2R64_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEM8916873.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            19599..20516
                     /gene="rbsK"
                     /locus_tag="U2R64_000016"
     CDS             19599..20516
                     /gene="rbsK"
                     /locus_tag="U2R64_000016"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEM8916874.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            20544..20939
                     /gene="rbsD"
                     /locus_tag="U2R64_000017"
     CDS             20544..20939
                     /gene="rbsD"
                     /locus_tag="U2R64_000017"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEM8916875.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            20939..22312
                     /locus_tag="U2R64_000018"
     CDS             20939..22312
                     /locus_tag="U2R64_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8916876.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            22669..24813
                     /locus_tag="U2R64_000019"
     CDS             22669..24813
                     /locus_tag="U2R64_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEM8916877.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(24865..25905)
                     /locus_tag="U2R64_000020"
     CDS             complement(24865..25905)
                     /locus_tag="U2R64_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEM8916878.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26182..27984)
                     /locus_tag="U2R64_000021"
     CDS             complement(26182..27984)
                     /locus_tag="U2R64_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8916879.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(27998..28750)
                     /locus_tag="U2R64_000022"
     CDS             complement(27998..28750)
                     /locus_tag="U2R64_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8916880.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(28759..29121)
                     /locus_tag="U2R64_000023"
     CDS             complement(28759..29121)
                     /locus_tag="U2R64_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8916881.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(29297..30169)
                     /locus_tag="U2R64_000024"
     CDS             complement(29297..30169)
                     /locus_tag="U2R64_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEM8916882.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(30220..30708)
                     /locus_tag="U2R64_000025"
     CDS             complement(30220..30708)
                     /locus_tag="U2R64_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HEM8916883.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(30846..31637)
                     /locus_tag="U2R64_000026"
     CDS             complement(30846..31637)
                     /locus_tag="U2R64_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEM8916884.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(31692..32300)
                     /locus_tag="U2R64_000027"
     CDS             complement(31692..32300)
                     /locus_tag="U2R64_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEM8916885.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(32293..32610)
                     /locus_tag="U2R64_000028"
     CDS             complement(32293..32610)
                     /locus_tag="U2R64_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8916886.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(32766..33494)
                     /locus_tag="U2R64_000029"
     CDS             complement(32766..33494)
                     /locus_tag="U2R64_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HEM8916887.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            33653..34534
                     /locus_tag="U2R64_000030"
     CDS             33653..34534
                     /locus_tag="U2R64_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8916888.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(34771..35814)
                     /locus_tag="U2R64_000031"
     CDS             complement(34771..35814)
                     /locus_tag="U2R64_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8916889.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(35817..36485)
                     /locus_tag="U2R64_000032"
     CDS             complement(35817..36485)
                     /locus_tag="U2R64_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8916890.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            36627..38963
                     /locus_tag="U2R64_000033"
     CDS             36627..38963
                     /locus_tag="U2R64_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8916891.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(39078..39389)
                     /locus_tag="U2R64_000034"
     CDS             complement(39078..39389)
                     /locus_tag="U2R64_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916892.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            39570..41045
                     /locus_tag="U2R64_000035"
     CDS             39570..41045
                     /locus_tag="U2R64_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HEM8916893.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            41092..41676
                     /locus_tag="U2R64_000036"
     CDS             41092..41676
                     /locus_tag="U2R64_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HEM8916894.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            41678..42097
                     /locus_tag="U2R64_000037"
     CDS             41678..42097
                     /locus_tag="U2R64_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HEM8916895.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(42378..42662)
                     /locus_tag="U2R64_000038"
     CDS             complement(42378..42662)
                     /locus_tag="U2R64_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HEM8916896.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(43014..43724)
                     /locus_tag="U2R64_000039"
     CDS             complement(43014..43724)
                     /locus_tag="U2R64_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HEM8916897.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(43721..45193)
                     /locus_tag="U2R64_000040"
     CDS             complement(43721..45193)
                     /locus_tag="U2R64_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEM8916898.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            45331..45804
                     /locus_tag="U2R64_000041"
     CDS             45331..45804
                     /locus_tag="U2R64_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8916899.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(45957..46508)
                     /locus_tag="U2R64_000042"
     CDS             complement(45957..46508)
                     /locus_tag="U2R64_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8916900.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            46613..47143
                     /locus_tag="U2R64_000043"
     CDS             46613..47143
                     /locus_tag="U2R64_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HEM8916901.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(47626..48069)
                     /locus_tag="U2R64_000044"
     CDS             complement(47626..48069)
                     /locus_tag="U2R64_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8916902.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(48085..49245)
                     /locus_tag="U2R64_000045"
     CDS             complement(48085..49245)
                     /locus_tag="U2R64_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8916903.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            49752..51452
                     /locus_tag="U2R64_000046"
     CDS             49752..51452
                     /locus_tag="U2R64_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916904.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(51554..52387)
                     /locus_tag="U2R64_000047"
     CDS             complement(51554..52387)
                     /locus_tag="U2R64_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEM8916905.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(52691..54856)
                     /locus_tag="U2R64_000048"
     CDS             complement(52691..54856)
                     /locus_tag="U2R64_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8916906.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            55116..57410
                     /locus_tag="U2R64_000049"
     CDS             55116..57410
                     /locus_tag="U2R64_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEM8916907.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            57403..58068
                     /gene="pgmB"
                     /locus_tag="U2R64_000050"
     CDS             57403..58068
                     /gene="pgmB"
                     /locus_tag="U2R64_000050"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEM8916908.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            58061..59068
                     /locus_tag="U2R64_000051"
     CDS             58061..59068
                     /locus_tag="U2R64_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEM8916909.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            59090..60109
                     /locus_tag="U2R64_000052"
     CDS             59090..60109
                     /locus_tag="U2R64_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8916910.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(60390..61758)
                     /gene="nhaC"
                     /locus_tag="U2R64_000053"
                     /pseudo
     CDS             complement(60390..61758)
                     /gene="nhaC"
                     /locus_tag="U2R64_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(61867..63288)
                     /locus_tag="U2R64_000054"
     CDS             complement(61867..63288)
                     /locus_tag="U2R64_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8916911.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(63531..65408)
                     /gene="tdc"
                     /locus_tag="U2R64_000055"
     CDS             complement(63531..65408)
                     /gene="tdc"
                     /locus_tag="U2R64_000055"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEM8916912.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(65699..66955)
                     /locus_tag="U2R64_000056"
     CDS             complement(65699..66955)
                     /locus_tag="U2R64_000056"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEM8916913.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(67067..67272)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            67535..68836
                     /locus_tag="U2R64_000057"
     CDS             67535..68836
                     /locus_tag="U2R64_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEM8916914.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(68905..69504)
                     /locus_tag="U2R64_000058"
     CDS             complement(68905..69504)
                     /locus_tag="U2R64_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8916915.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            69758..70639
                     /locus_tag="U2R64_000059"
     CDS             69758..70639
                     /locus_tag="U2R64_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8916916.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            70652..72262
                     /locus_tag="U2R64_000060"
     CDS             70652..72262
                     /locus_tag="U2R64_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HEM8916917.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(72339..72998)
                     /locus_tag="U2R64_000061"
     CDS             complement(72339..72998)
                     /locus_tag="U2R64_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8916918.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(73281..73946)
                     /locus_tag="U2R64_000062"
     CDS             complement(73281..73946)
                     /locus_tag="U2R64_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HEM8916919.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(74093..74698)
                     /gene="dhaL"
                     /locus_tag="U2R64_000063"
     CDS             complement(74093..74698)
                     /gene="dhaL"
                     /locus_tag="U2R64_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HEM8916920.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(74726..75736)
                     /gene="dhaK"
                     /locus_tag="U2R64_000064"
     CDS             complement(74726..75736)
                     /gene="dhaK"
                     /locus_tag="U2R64_000064"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HEM8916921.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(75711..76157)
                     /gene="dhaM"
                     /locus_tag="U2R64_000065"
     CDS             complement(75711..76157)
                     /gene="dhaM"
                     /locus_tag="U2R64_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEM8916922.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            76260..76580
                     /locus_tag="U2R64_000066"
     CDS             76260..76580
                     /locus_tag="U2R64_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HEM8916923.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(76692..77561)
                     /locus_tag="U2R64_000067"
     CDS             complement(76692..77561)
                     /locus_tag="U2R64_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8916924.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(77657..78961)
                     /locus_tag="U2R64_000068"
     CDS             complement(77657..78961)
                     /locus_tag="U2R64_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8916925.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(78958..79467)
                     /locus_tag="U2R64_000069"
     CDS             complement(78958..79467)
                     /locus_tag="U2R64_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916926.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(79642..81777)
                     /locus_tag="U2R64_000070"
     CDS             complement(79642..81777)
                     /locus_tag="U2R64_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8916927.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(81860..83515)
                     /locus_tag="U2R64_000071"
     CDS             complement(81860..83515)
                     /locus_tag="U2R64_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8916928.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(83517..83831)
                     /locus_tag="U2R64_000072"
     CDS             complement(83517..83831)
                     /locus_tag="U2R64_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEM8916929.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            84001..84261
                     /locus_tag="U2R64_000073"
     CDS             84001..84261
                     /locus_tag="U2R64_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEM8916930.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            84275..84589
                     /locus_tag="U2R64_000074"
     CDS             84275..84589
                     /locus_tag="U2R64_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HEM8916931.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(85319..85873)
                     /locus_tag="U2R64_000075"
     CDS             complement(85319..85873)
                     /locus_tag="U2R64_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEM8916932.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(85999..87928)
                     /locus_tag="U2R64_000076"
                     /pseudo
     CDS             complement(85999..87928)
                     /locus_tag="U2R64_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(88234..88950)
                     /locus_tag="U2R64_000077"
     CDS             complement(88234..88950)
                     /locus_tag="U2R64_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEM8916933.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(88951..90774)
                     /gene="glpO"
                     /locus_tag="U2R64_000078"
     CDS             complement(88951..90774)
                     /gene="glpO"
                     /locus_tag="U2R64_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEM8916934.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(90788..92284)
                     /gene="glpK"
                     /locus_tag="U2R64_000079"
     CDS             complement(90788..92284)
                     /gene="glpK"
                     /locus_tag="U2R64_000079"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEM8916935.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(92420..93880)
                     /locus_tag="U2R64_000080"
     CDS             complement(92420..93880)
                     /locus_tag="U2R64_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8916936.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(93870..95165)
                     /locus_tag="U2R64_000081"
     CDS             complement(93870..95165)
                     /locus_tag="U2R64_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8916937.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(95497..96174)
                     /locus_tag="U2R64_000082"
     CDS             complement(95497..96174)
                     /locus_tag="U2R64_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HEM8916938.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(96204..97295)
                     /locus_tag="U2R64_000083"
     CDS             complement(96204..97295)
                     /locus_tag="U2R64_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEM8916939.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(97396..97830)
                     /locus_tag="U2R64_000084"
     CDS             complement(97396..97830)
                     /locus_tag="U2R64_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8916940.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(98414..99871)
                     /gene="ascB"
                     /locus_tag="U2R64_000085"
     CDS             complement(98414..99871)
                     /gene="ascB"
                     /locus_tag="U2R64_000085"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEM8916941.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(99868..101763)
                     /locus_tag="U2R64_000086"
     CDS             complement(99868..101763)
                     /locus_tag="U2R64_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8916942.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(101821..103596)
                     /locus_tag="U2R64_000087"
     CDS             complement(101821..103596)
                     /locus_tag="U2R64_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8916943.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(103646..105142)
                     /locus_tag="U2R64_000088"
     CDS             complement(103646..105142)
                     /locus_tag="U2R64_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8916944.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(105336..106958)
                     /locus_tag="U2R64_000089"
     CDS             complement(105336..106958)
                     /locus_tag="U2R64_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEM8916945.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(107286..108599)
                     /locus_tag="U2R64_000090"
     CDS             complement(107286..108599)
                     /locus_tag="U2R64_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEM8916946.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(108844..109068)
                     /locus_tag="U2R64_000091"
     CDS             complement(108844..109068)
                     /locus_tag="U2R64_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916947.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(109088..109510)
                     /locus_tag="U2R64_000092"
     CDS             complement(109088..109510)
                     /locus_tag="U2R64_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEM8916948.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(109653..110363)
                     /locus_tag="U2R64_000093"
     CDS             complement(109653..110363)
                     /locus_tag="U2R64_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916949.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(110381..110878)
                     /locus_tag="U2R64_000094"
     CDS             complement(110381..110878)
                     /locus_tag="U2R64_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8916950.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(110915..111367)
                     /locus_tag="U2R64_000095"
     CDS             complement(110915..111367)
                     /locus_tag="U2R64_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8916951.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(111502..112107)
                     /locus_tag="U2R64_000096"
     CDS             complement(111502..112107)
                     /locus_tag="U2R64_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEM8916952.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(112557..113177)
                     /locus_tag="U2R64_000097"
     CDS             complement(112557..113177)
                     /locus_tag="U2R64_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEM8916953.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(113179..114048)
                     /locus_tag="U2R64_000098"
     CDS             complement(113179..114048)
                     /locus_tag="U2R64_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HEM8916954.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(114071..114478)
                     /locus_tag="U2R64_000099"
     CDS             complement(114071..114478)
                     /locus_tag="U2R64_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEM8916955.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(114497..115786)
                     /locus_tag="U2R64_000100"
     CDS             complement(114497..115786)
                     /locus_tag="U2R64_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8916956.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(115813..116115)
                     /locus_tag="U2R64_000101"
     CDS             complement(115813..116115)
                     /locus_tag="U2R64_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8916957.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(116140..118233)
                     /locus_tag="U2R64_000102"
     CDS             complement(116140..118233)
                     /locus_tag="U2R64_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8916958.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(118722..119486)
                     /locus_tag="U2R64_000103"
     CDS             complement(118722..119486)
                     /locus_tag="U2R64_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HEM8916959.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(119597..120466)
                     /gene="mdcB"
                     /locus_tag="U2R64_000104"
     CDS             complement(119597..120466)
                     /gene="mdcB"
                     /locus_tag="U2R64_000104"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HEM8916960.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(120491..121567)
                     /locus_tag="U2R64_000105"
     CDS             complement(120491..121567)
                     /locus_tag="U2R64_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEM8916961.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(121591..122184)
                     /locus_tag="U2R64_000106"
     CDS             complement(121591..122184)
                     /locus_tag="U2R64_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HEM8916962.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(122188..123864)
                     /gene="mdcD"
                     /locus_tag="U2R64_000107"
     CDS             complement(122188..123864)
                     /gene="mdcD"
                     /locus_tag="U2R64_000107"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HEM8916963.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(123854..124153)
                     /locus_tag="U2R64_000108"
     CDS             complement(123854..124153)
                     /locus_tag="U2R64_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HEM8916964.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(124255..125901)
                     /gene="mdcA"
                     /locus_tag="U2R64_000109"
     CDS             complement(124255..125901)
                     /gene="mdcA"
                     /locus_tag="U2R64_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HEM8916965.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(125908..126819)
                     /locus_tag="U2R64_000110"
     CDS             complement(125908..126819)
                     /locus_tag="U2R64_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEM8916966.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            126939..127796
                     /locus_tag="U2R64_000111"
     CDS             126939..127796
                     /locus_tag="U2R64_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8916967.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(127983..128345)
                     /locus_tag="U2R64_000112"
     CDS             complement(127983..128345)
                     /locus_tag="U2R64_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEM8916968.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            128691..130130
                     /locus_tag="U2R64_000113"
     CDS             128691..130130
                     /locus_tag="U2R64_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8916969.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(130137..132689)
                     /locus_tag="U2R64_000114"
     CDS             complement(130137..132689)
                     /locus_tag="U2R64_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEM8916970.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(132803..134134)
                     /locus_tag="U2R64_000115"
     CDS             complement(132803..134134)
                     /locus_tag="U2R64_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8916971.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(134100..135578)
                     /locus_tag="U2R64_000116"
     CDS             complement(134100..135578)
                     /locus_tag="U2R64_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8916972.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(135883..137718)
                     /gene="tdc"
                     /locus_tag="U2R64_000117"
     CDS             complement(135883..137718)
                     /gene="tdc"
                     /locus_tag="U2R64_000117"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEM8916973.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            138188..139615
                     /locus_tag="U2R64_000118"
     CDS             138188..139615
                     /locus_tag="U2R64_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8916974.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(139707..140072)
                     /locus_tag="U2R64_000119"
     CDS             complement(139707..140072)
                     /locus_tag="U2R64_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEM8916975.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(140069..140434)
                     /locus_tag="U2R64_000120"
     CDS             complement(140069..140434)
                     /locus_tag="U2R64_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEM8916976.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(140626..140874)
                     /locus_tag="U2R64_000121"
     CDS             complement(140626..140874)
                     /locus_tag="U2R64_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916977.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            140873..141001
                     /locus_tag="U2R64_000122"
     CDS             140873..141001
                     /locus_tag="U2R64_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HEM8916978.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            141058..142752
                     /locus_tag="U2R64_000123"
                     /pseudo
     CDS             141058..142752
                     /locus_tag="U2R64_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
     gene            142756..142875
                     /locus_tag="U2R64_000124"
                     /pseudo
     CDS             142756..142875
                     /locus_tag="U2R64_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            143526..144659
                     /locus_tag="U2R64_000125"
     CDS             143526..144659
                     /locus_tag="U2R64_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEM8916979.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            144690..145010
                     /locus_tag="U2R64_000126"
     CDS             144690..145010
                     /locus_tag="U2R64_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HEM8916980.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(145039..145503)
                     /locus_tag="U2R64_000127"
     CDS             complement(145039..145503)
                     /locus_tag="U2R64_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8916981.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(145635..146889)
                     /locus_tag="U2R64_000128"
                     /pseudo
     CDS             complement(145635..146889)
                     /locus_tag="U2R64_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(146918..147235)
                     /locus_tag="U2R64_000129"
     CDS             complement(146918..147235)
                     /locus_tag="U2R64_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEM8916982.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(147261..147581)
                     /locus_tag="U2R64_000130"
     CDS             complement(147261..147581)
                     /locus_tag="U2R64_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8916983.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(148045..149460)
                     /locus_tag="U2R64_000131"
     CDS             complement(148045..149460)
                     /locus_tag="U2R64_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8916984.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(149477..150793)
                     /locus_tag="U2R64_000132"
     CDS             complement(149477..150793)
                     /locus_tag="U2R64_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8916985.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(150943..151641)
                     /locus_tag="U2R64_000133"
     CDS             complement(150943..151641)
                     /locus_tag="U2R64_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEM8916986.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(151930..152886)
                     /locus_tag="U2R64_000134"
     CDS             complement(151930..152886)
                     /locus_tag="U2R64_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8916987.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(152999..153832)
                     /gene="msrA"
                     /locus_tag="U2R64_000135"
     CDS             complement(152999..153832)
                     /gene="msrA"
                     /locus_tag="U2R64_000135"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEM8916988.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(154007..>155597)
                     /locus_tag="U2R64_000136"
     CDS             complement(154007..>155597)
                     /locus_tag="U2R64_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916989.1"
                     /translation="IIVSSIYSFIFFKNTQSIYTTGDLSFHLSRIKGLSTIFTSPINY
                     ETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNLCTTLVAYHYGERF
                     LKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFYAYQIISGKEEKYP
                     SVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAIFKKLFSAAGMTLV
                     LTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDLTTYSMGLVGLLSL
                     CIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLLQFPWRILSLQIIF
                     SSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQKIISQPGHIVVNKE
                     TVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPYKTTGSSIIYRVTN
                     EKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVADIKVSTSYTVTTII
                     SYLVTLTAYLCLFFKIVFHKR"
BASE COUNT        45893 a        32153 c        27087 g        50464 t
ORIGIN      
        1 gttttaacct tccggttttg attggataac cctatgaacc atcgttattt taatttggta
       61 ttaactcatt tcttttgaga taatatattt attggattga gaggctaagc cgttcccccc
      121 ttgggccatt gaacccgcac tcgagagact ggctcctctc tctgataagt ggattgcgta
      181 tgagttagat gttgaaagtc cttactttac tccgtatctc gtacaaggta gtgacgcttt
      241 tcagttgagt ggatttcaat ccaaaattct ttttttgaaa ggtcagatat acatgtactt
      301 tttaggcatt gatatcggta aacgcactca cgttgcttct atcatgaacg aggaaggaaa
      361 ggtattacta aaaggttttt catttcctaa caccactgaa ggagcagagt cattaattga
      421 gcgaatggtc gactattccg gagcacccag tgactttgtt atagggatgg aagccacggg
      481 gcactattgg ctgtccatct tttcatacct tcacgaatca gattatttga ttcacgttgt
      541 gaatcccctt caaacagacg gatggcgtaa aggtacagaa atacggaaac gaaaaaacga
      601 tattattgat tctgttttga ttgctgactt aatgcgctat ggctcatttg tcgaaacggt
      661 cttatccgat gaaaatgttt tttctttgaa acaactttct cgttaccgaa cttatttagt
      721 aggtacagcg agcgacttca aaagaaaaat tatagccgta ttggatcaag tctttccaga
      781 atacgcgacg atttttacca agcagggcgt tttcggaaaa gcttctaaag agttattgct
      841 ggcgtttagt gccccgatcg acttagaaaa catttcctca gaaactttgg cccaatactt
      901 agctgagtta agcaggaacc gaatcaaggc agaaaaagcg gaccaattga agcaagcagc
      961 ttctaactcc tttggagtaa aatttgctca agaagcgttc accttccaac tacgttcaat
     1021 gattgaacaa ttaaaattca ttgaaagcca aataaaggaa acggaaagag aaatcaagca
     1081 cataatggac actttaaatt ctgttattct cacaattcct ggaattggtc ctataaacgg
     1141 tgcgactatt cttggtgaga tcggagatat tcaaaaattt tctaacccga aaaaactcgt
     1201 tgcttacgct gggatagacg cttccgtgac acaatcaggg caatatgagg caacgcataa
     1261 tgttatgagt aaacgagggt ctccatattt gcgaaaagcc ttgttttcgg cggctttagt
     1321 agcttctcaa tgtgatcctg tttttagtgc gttttaccag aaaaaagttt ccgaaggaaa
     1381 acatcatcta actgccttag gtgcggtttc tcgtaagctt tgttacgtga ttcatgctat
     1441 tttgactaaa aacgagcctt atataattgt ttctgattag ctattgaaca ttcaaaaaaa
     1501 ctaatggtaa gaagcttatt tgttgtaccc ttttttcgga attatctgtt ataaaatatt
     1561 ttttgatttg gctaattttt acttgactct atatagttag tctctcttct atcactttcc
     1621 ttttttcaca cgactcccgg tttctttgat aaatctcgat actttcaatt ttcttgaatt
     1681 tttcatttga ggtacacata gatacagacg atttcttgct ctagtcatcg caacataaaa
     1741 tagtcttcgt tcttcttcta tcgtcgttac tggttctgct tttatttcat taaagtcgat
     1801 tactttcttt tctgtcgctc cgttataagg caaacttcct tcgttacaac caatcaaaaa
     1861 gacatttcgg taactaagac ctttactttt gtgaatgctc tggatacata gtgcatcaag
     1921 ttttccttgt ctgtaagcaa tcaagcgggt ttttaattct ttagctgtcg cttgggtttc
     1981 ttgcgataag gcttggagtc ttctgaaagt agcatgctgc tttacttctt ctcgtatcca
     2041 ttcttgatca ctctggtcga tttccttagc tatacgtggc agatgaagat agctttgaac
     2101 aagcgaatag atttcttgat gctggtctgt tttacgcaac gcttcctcaa actctcggat
     2161 ttctgcagat ttcgatttta aattggggct tatcgacaaa atataatctg caacggatat
     2221 attttgatat ttaggagaaa agtattgatc gcattcactt tttttcaggt agcagtctgc
     2281 catcagctgc cggagcaatt gctggtaggc ctgatttttc ttttgcagat tcagtgctgt
     2341 ttgccaatga acaatttttt gatagaaatg ttggaaagac ttgataccaa agataccttc
     2401 atatggacta tctgcttcca gtacaaaagg aatattcgtt ttcagcagag attggacaag
     2461 ctgctgcgtt tgtgaagctg atcggtataa tatgattgat tccttatatt tcccattttt
     2521 ttgaataaat gtctgaattt gtttgattag ccactgactt tctgctttag tatcagaaaa
     2581 caaataggct tccataacac ctgcttcttt ttgtgctgga atcatcgcct ttggtatccg
     2641 atcattttta ttatagctga tcaatctatt tgctccttgg acaatagctg cccgagaacg
     2701 ataattagtt aataagaaaa gagttttggt aggatattct ttttcaaagt tcttgatgta
     2761 tgctggctct gatcctctga atccatagat actctgatca tcatctccaa caacaatcaa
     2821 cttgatcctg ttttcctttg tcatccgttt cacgatttcc cattgaagtg gattagtatc
     2881 ttgaaattca tcaatgaata gataatcata tttttggccg atataatgct ggatctcctc
     2941 attctccaaa gcgcttttca gattttggag tacatcattg aactctagca attgctggct
     3001 tcttttttgt tcttggagtt ccgtgagcaa tccatacagt cgttctgata tcggctgtcg
     3061 tgcattctta tcaatggaat catatttttc tttaactaac tgaaccattt cttctactga
     3121 aaggttcata ttctgccaat agtctaaccg agaagcaatc gttttttctc catattgatc
     3181 aaatatataa agattatatt tacgtatcag ctgttgcaaa acagcattca ctttttgtgc
     3241 agtatccttt gaaaagtctc cttgtattcc ttgcattgct acttcaggaa attttcgaca
     3301 aatttcattg tatatcctaa aaaagatact atggaatgtt ccgatatgga cagcggtttt
     3361 tctctggctg aaattatcta ctcgtttttt tagttcattt gcagcgttcc ttgtaaaagt
     3421 gatcattagt atgcgttctt cgtctacttg tttttgcgtc atcagataaa cagcttttgc
     3481 acagattgtt tgcgttttgc cgctcccagc tcctgctatg attcgaagat gtttcttcat
     3541 atcatatgtg atagctgctt tttgttcttg attgaagcga ttataggaac gtttctccat
     3601 cattttaaag aaagagctgt ttccttcact ttcttttact tgtacttctt cctcaataag
     3661 tccgggtgct tcgccataag ccgcttcata ggtagcaatg atttcttctt gtagccgaaa
     3721 gacttgttga agctttttat acttgttctc ccagcgtttc aattcttttt gtaatcggag
     3781 aatttctttt tcattcaact gattgatttc cttcccatct ttcttctttg aatttgttta
     3841 tttcaagttg gttatttaaa gtttcgttgt ctattttttc tttatactaa cagacctttc
     3901 taaaaatgaa aatgggaagc gatatgattt tagttttctg aaaatttttc ctttttttca
     3961 atcgtttatg ctaagataag gaagacaaaa atattcataa aaggtgatga aaaaaatgca
     4021 gacttccttt cacgaggggc gtacaatagg acttttgctg acatttatcg gaggagccat
     4081 ggacagttat acttatatcc aatatggtgc ttttgcctct gctcaaactg gcaatatcat
     4141 tctatcgatc atccaagcat ttgacggaga atggctaagt gttggtaaaa aagtattgtc
     4201 tacccttttc tttttcttag ggattcttct aacaaagtat ctaattgatt attttagaaa
     4261 aaaagaaaaa catttctggc gcttgtttgt tctatattat gaagcagtga tttttttctt
     4321 tgttagtttg acacccgtcc atgagcatcc cgcattagta acgattttga ttgcttttac
     4381 tgcatcgatc cagtgggtag cttttgataa aatcaacggg cgtgcctaca ctaatttatt
     4441 tacaactgga aatttaaaag gggtagcaac gaacttatat gattattgta tttctaaaga
     4501 aaaagcagat tttgatcgat ttttccacta tctaagtgtc gttcttgcct ttatcgcagg
     4561 agctattgtc cttgttttct gtcatcatct gtttggcgcc cattcgattt tgatcgtttc
     4621 cattttattt ttgatcatgg ccctcactca gacatttcat ttatggcaat tttatcatac
     4681 gaatcggttc actatttgat ctcaatgaat caaaaaaact aagcaagatg ctgctcacag
     4741 agaaatatct gcgagtgagc aatttgctta gtttttatat tatttagttg taaagattcc
     4801 ctttgctttc gggttatttg tagtgtagcg gatcgactgg gcatctgcct cttctgtcat
     4861 tttctttgcc cgcatcttga tttcttgtac gatttgttct ccacatgccg gatcggctac
     4921 gaaatcatat ttgtccccat cgatcactat tttgggacat atatcaaact gttcatacca
     4981 ctcttcgtat cgtcgattga gttctttata gtaggaatag agttcaggat cttgttctag
     5041 ctgttcatat tcccggcctc tttttttgat tctcgctaac atagtttcaa aggatacacg
     5101 aatataaacc agtagatctg gtttcttttg tggcgaaatt tcttctaact ccttcagcat
     5161 cgtttctaaa agaccttcat actgctttac ttctacttca gaaacacgcc ctaaatctgc
     5221 attcaaatga aacagcatac tatcttcgta gatggagcgg tctagtacgt tgtcatcatg
     5281 gctgaaagca tctttgattg ccaaaaagcg tttgttcaaa aagaaaatct gtaataaaaa
     5341 agtatacttt tctggattag aataaaatag cggcaatact tcattatctt ccacgttctc
     5401 ataaaaaggt tttgtttcta aatcttgggc aagcatttca gttagtgtgc ttttccctgc
     5461 accgatcgtt cctgcaacaa tgatcacaat tatcggcatc cttcctgtaa taaaatctgt
     5521 tcttcatttt actacttcat ttatagaaat aaaagccttg actttatctg ctccttaaaa
     5581 gctacttctc taaaagtagc caaaagtaac tcctattcat gaaaataaag gctgtgacaa
     5641 aagtcttgtc gcagcccttt tttcaaataa acagtattct cctgccaaca cctcggtcac
     5701 aaggcaatat tcataaaaca tgaaaagctg ttttttaaca ttattccttg taactcagag
     5761 ctaaacggga gactcacaac ctctttatgc tctcaacatt ttatctgttt ttattcttct
     5821 attgtacttg atttgcgtac aactaactgc cagtgcagat tatgagcggt atcattgtct
     5881 tctactgcgc atttcatgac acgtatcatc acactatttt catagatttt ttctattttt
     5941 ccttttattg gtgattcaaa taaatcagat ttaaatgcat atgtttcgcc gacttcaaac
     6001 aattgttcat tttccataag aatccctcca tcacctttta taaggtcagt aattttttaa
     6061 cataaatcac tcgaaaaagc acaaacttgt cataaaaagt acttttcgta tcaaaactgt
     6121 cacttttttt ggtaaggttc ttggaaaacg aagatttttt taggagatca tgacggtttt
     6181 gatgtcaaaa ccacttttta tgaaacaaaa gacgtttttt atttttttta gcataaaatt
     6241 tgtggtggag gtacgtatga gatgaaagat aaagttgtga acaaattatt agaagcctta
     6301 ttcagcggag acaaatcgga agaagatatg gtgtatgtcc aagtaaaatt tgtcttagaa
     6361 gttttattga ataatcttgg aaaactagcg gtcgttctag tcttttctct ggtgacaggc
     6421 tcatgggcgg aaacaggaat cacctttctt tcttatatct gcatccgcag atatgcttat
     6481 ggattgcatt ccgactctga attcgtttgt ctgctgtgga cactacttta tttatggggc
     6541 gttcccttgg tgatgaaaca tctgcaattg actatctcct tcccaatgat ggtctttttg
     6601 ttaatcagct gctttttgtt actgcttcgc tatggatcaa gaggtacagc aatcaatccc
     6661 attgaacccg agaaacgtcc cccattatta aagaaggcga tcagcatgtt tctaattttt
     6721 tctctcatta cgttattttt ctcagcttct tacttttcta cctatttgct acttgggatt
     6781 gttttagaaa tagctacgtt gcttcctatt acaaactact tgatgaattt tggaggaatc
     6841 tttcatgaaa aaaacaatca ttaaacaatt aactaactta tctgactttt ttgtatctgg
     6901 ctgctgcttt ggtatgagtt ctgaattcaa aatccctgaa aaattaaaaa aataatacgc
     6961 caattgtgct ataatttggt aaaaatcaat gggagctgta ctttatgttt ttatggtcca
     7021 tagcgttgca atatttgatt tacacaattt gtatcttatt gattgaccat cacatccgat
     7081 acaaatatct gtttgcggga gtcattctga tttcttgtat tttgattgga tgggtctatt
     7141 cgattttagg gatttttact gctctaattg ctataggaat gctgatgctt acttttttct
     7201 tcttttcgac ttcgcgtcaa caattggttt acgcgcttcc ttttgggtta ttgacgtcgc
     7261 ttttaggaga tcacttaaca agcatcggcg atttttttgt tttgaaatct tcggttattg
     7321 aaccaggaga ttcattgcag tattttcaca ttgtcttatc cgctttttta tctgctttat
     7381 tagctttttg tttaaaaaaa tcgttagaga cttggtttca cactgtggac cgccgtatga
     7441 tcggtacgat cgggacattg atattattta catactatat cattattttt tatacccgtt
     7501 tttctggtga aacacctgat gtcttagctt tgaatacgag ttttttcatt ctatatctgt
     7561 gtgttggcct gatcatcttg gtttattatt ggaaaatctc taataagaaa ttagctgatc
     7621 agttattaga gcaacaagtc aggatgcaac aggattatat caaagatcta gaaaaaaact
     7681 atcaagactt gagagaattc aaacatgatt accaaaatct gcttttttct cttcacagct
     7741 atatttcaga aggcgactta gaaggattac ggtcttatta tgatcaaacg atattaccta
     7801 cacgccagat gatgaacctt tttccggcca atctaagtat gttggataat atgaaagttc
     7861 ctgagatccg tagtttactg tcattaaaac tcatgatggc acaggaaaaa gggttgatcg
     7921 tccagcttca ttttcctgag ccaatcgaac tggatacgaa acatacggta aaccttgtac
     7981 gtatgcttgg tattatcttg gacaatgcga ttgaaggagc tagtgctgca aagaagaaaa
     8041 aaatcgaatt gaccatactc aagaagaatc attccgtgat gattcgtgtg atcaatacaa
     8101 caacaaatac attaccgtta aaccagttga aacaaaaagg gttctcaaca aaaacaaatc
     8161 caaaaaacga aggccttggc ttgtttatct tggatgaatt gacaaagacc aatccttatc
     8221 ttttccttga aacatcaatt gaaaaccagc gtttttctca aacgatttat atacaaataa
     8281 aataaaggag taatgatatg attcccattt atatttgtga agacgatcca aaacaattag
     8341 aagttttatc aacggtgatc aaaaatagaa tcatgattga aaacttagac agttatgtcc
     8401 atatttctac ctctgatccg gaagaacttc tcaatgcagc caagatcaga acttcttctt
     8461 ttggtattta ctttttagat atcgaactag aagacagtga aatggatggt gtagcgatcg
     8521 gtaaattgat ccgtgaatta gatcctttag gaaaaataat ctatgtgact tcccatacgg
     8581 aaatgtcgat gaaaatctta aaaagcaaca tcgaaccgac tgattatatc gtcaaagaag
     8641 atctttatga tttaaaagaa aatgtcgagc atatcctgag caaaattttc gaagattttc
     8701 aaatgtccca aatccaaaaa gatatcttca aaatagagtt taatgatgag atcaaatttt
     8761 taccgatcaa agacatccaa tatttttcta cttcgctagg agcgccacat aaactggaag
     8821 tccatttgac tcatgcccaa ttacaattct atgagaagat caaagaaatc gagaaaatgc
     8881 atcggaattt tatccgttgt cataaatcct atgttatcaa tacacaaaat gtgcggtcga
     8941 ttaataaaaa aaccagagaa gtcacgttgg caaacggcga gaccatccca gcctctatcc
     9001 gtggattaaa gaaattgatt tcataaaaag aaccgaatag tttggaccga ctaaatgacc
     9061 agccgatcca aacccttcgg ttcttttttg cctatcagtg caaaagcatt tcctgtgcaa
     9121 tttcacgtcc atccattgta tctggataaa atgttggcca attctccatt tctttcagca
     9181 atacttcttg actttcattt cctgcatata aatgaaaatg ttcggagtca gccggtgcaa
     9241 tcgtgtgatc actgaattga atatatctaa aagcgccact ttccttatct tctgcttcga
     9301 atagatacct tacgccacgg tttcctgcct cgtaggtcaa gatttctttc cctacataac
     9361 gataatttga acgtttcgtt gttccattct taaacgtaaa tgccatctct ttctcactga
     9421 tcttgattga agcaatatct gtttgatagc ccttcgtata atattcttta tattcttgtg
     9481 ctgtcttatc ctgattcaat ttttctttat attcaaaaac aggatcaaaa gtcccatctt
     9541 ctacatacgt atctactgtt tgccaagttc ctgcccaatc tgaaagagag cgatcttgta
     9601 catcctcgtc ttcaaaataa ccgttgtaga cgctcttttc ttttttgggg gtcaaagtat
     9661 cttctagcgg gttttctgtc tctgtcgttt ttttcaacgc ttcgaggttt gcttccatga
     9721 tagaaagata gttttctcca ttttctattt gttcattcgt caatccttcc aaaggattca
     9781 atacttctaa agatacacct gcttcgtttg ctaacgttct ggcaatacta tctttggcgt
     9841 tttcttcaaa ataaatatag ttgattccat gttctttaac aaagtgtttc agttcagcaa
     9901 ttctcgccgc agacggttct tcactagaag aaagaccagc aatcgatact tgattcaatc
     9961 catattctaa cgctagatag ttgaatgcag catgttgcgt gacaaaagat ctttgttttg
    10021 cttgcttaaa ggtttcttga taaagctgat ggagtgcttg aagtttctcg gtataggctg
    10081 ctgcattttt tgtccatact tcctgttttt ctgggtaagc ttcaatcagc tgatcacgta
    10141 tgtttgctac ctgcttgatt gctaaacttg gagctagcca tacatgtggg tctagctcat
    10201 gtgtatggcc ttcttccccg tgttcatggt catgatcatg tccttcttca cttcccggaa
    10261 gtaaaagcat accttctgtc gcttttatcg tatggacatt gccttcttgt aatgtttttt
    10321 ggattgcggg gacccatgtt tccatgtttt catcattata aacaaagata tctgtatctt
    10381 ggatctttgc catgtcttta gcagaaggtt cataatcgtg ggaatcagtc cctgctggaa
    10441 tcaataactc tacttctcct tcatccccga cgattgcttt tgtaaaatca tacatgggat
    10501 aaaaggtcgt catcacgctc aatttttctt tactgtcctc ggctttccca cttgccccgc
    10561 aagcagttaa catacctgct aaaaccagca tggccaatat acctatcaat cgtttcattt
    10621 atgacactcc tcttctcatc ttctttcatt tgaatgttcc gattcgcttt tcgcaaaccg
    10681 taatagttac gttttagcaa caggatttaa tttatcatat ggttaaaaga actgtcaagc
    10741 gttttcttat tttaattgat gagaaagttt atatgaatga ttgacgatat ttttgcaatc
    10801 aacctctatc attttccttt tatacccgct tttgtctata atgaagttat agataaagga
    10861 ggaaaaagag tgaaaaaaga aacagataca acgaatcgtt tgatccgctt tttaggagga
    10921 aaaacctctt actatgtttt aggaatagtt atcttacttg cgctgatcat ttattttttc
    10981 catcagatct cgtttatatt caagcctgtc ggaatcatta tcgctactat cttgccccca
    11041 ttattgtttg cactgatctt gtattatctt ttggaaccag tcatcaaacg tttgagcaag
    11101 cacctttcga ggaacttgtc agtcattatc gtttatgtga ttattttatt tttattgggg
    11161 cttggaagca tatggcttat tccttttctt gaagaacagg caaagacatt gatcagtagt
    11221 ttgccagatt tgtttcaaga ttttcaagag agtctccgac aatttttgga gaaaacacct
    11281 tttgccgatt catttaatca atttttcgct tctattgacg acgtgacgtc tgatatagct
    11341 ggatttattg gaaattattg ggaaagtggc gcacaacgga tcagcaacat tttttcaact
    11401 gttacagcta tttttattac tttatttact ggtccaattg tcgctttttt ccttttgaga
    11461 gatcctcaaa aattttatca gtcagtttta gcgattgtcc caccagcatt tcgtacagat
    11521 tttaaaaatt tgacaaagat tgctaatcaa caattgggtt catttctaaa ggggcaaatc
    11581 attgcttcat ttatccttgg agcagtctac tgggtttgtt tcttactgat cggattagaa
    11641 tttgctagtg ttttagctat ttctgctggg ttgttatgta tcattccata tattgggccg
    11701 tttatcgcct tctttccagg tttgatcatt gcattccaag actctacttt tatggctgtc
    11761 aaatttgtca ttgtctggtt tgccgtacaa cttctccacg gtgacttggt gattcctcga
    11821 gtaatgggtg atcgtttaca gatccatccg attacgatct taatcgtttt acttgtcatg
    11881 ggtgatctaa tgggaattgt gggcgttatt tttggtattc ctatctatac gttagtcaaa
    11941 ttactcgtta cttttatttt ccgtaaattc aaacaacgct acaataaatt ttatggcgat
    12001 aaaggagagt atgaaaactc ttcattttct gaagaagatt attttaaata aaacacaaaa
    12061 cgtcgatctt acgagaatag ctcgtaggaa cgacgttttg tgtttttgtt ttaatttttc
    12121 agcaaagcaa ttgcctggta tggttttagc tccagacttt gatgaagaac agtatcggaa
    12181 taattatcga taagaatatt ggcttctgtg aatccttctg ggatggcgat ccttgtatct
    12241 ttatcataga aatttgttaa tacaagcagc tgctgtcctt caaattggcg aagaaagcca
    12301 taaacttccg gatgatttgc ttcataagca tgataatctc cttgtgcaac gattggatat
    12361 gtttttctca gccgaatcaa tttcttgtaa taggacaaaa tagaatcttc agaagatagt
    12421 tctttttcta cattaatctc ttctagcttg cctccaactt ttaaccaagg tttccctgta
    12481 gtaaatcctg cttgttctgt gtctgaccat tgcatgggtg ttcgagagtt atcgcgagat
    12541 tttgctttga tccgacgaaa cgcttctttt tctgtgaatc cttgttcaag gagtaactta
    12601 taagcattca aactttctac gtcaatatag tcggaaatcg atgaatagtc tgggtcgatc
    12661 atgccgattt cttctcccat ataaatatag ggcgtcccac ggttcaaatg gatcatggtt
    12721 gctagcatct ctgctccttg ttttcgatac tgatcgatag ctacaaatcg attgagcgca
    12781 cgtggctgat catgattatt aaaaaataga gcattccagc cgttaccctc actcatcttt
    12841 tctccccatg tatgaaatag tcgctttaat tctgcaaaat caaatggagg agtagaccat
    12901 ttattcccat tttcataatc gactttcaaa tgatggaaat taaagaccat tgataattct
    12961 tctctactag gttctgtata caagatacaa ttttcgatcg tcgtagagct catttcaccg
    13021 actgtgatga tagtggaatc cgtcccaaac gttgcttggt tcaattcttt tagatacgta
    13081 tgggtgattg gtttgtccgt atattcaggt ttgccatcat tttctttatt atttttcaat
    13141 tgttcgtctt taccgataac attgataaca tcgaaacgga atccttttac ccctttttcc
    13201 atccaaaaac gaacaacttt gaatagttcc tctcttactg cttggttccg ccagttcaag
    13261 tcagcttgtg tccgatcata taagtgcaaa taatatttcc ccgtatctcc aaatggcgac
    13321 caagcacttc caccaaattt tgatacccaa tccgttggct cttctcttaa aatgaagaag
    13381 tcctgataat gctggtcccc tgctagtgct tttttgaacc attcatgttc tgtcgaaacg
    13441 tgattcagca ccatatcgag catgatttct atccggtatt tctttgcttc ggctattagc
    13501 tgttcgaatt cctccatcgt accaaagata ggatcgatgg ctgtgtaatc agagatatca
    13561 taaccgttgt ctttttgagg gcttggataa atagggttta gccaaatcat gtcgatgcct
    13621 agatcattca gatacgggag tttttctttg attcctttta aatctccaat tccatcacca
    13681 ttactgtctt tgtaagattt gggatagatt tggtaaatga ctttgtcttt aaatgtcatg
    13741 gatatttacc tccattcaac tgatttatta cctaccacaa cttatatata caagttatca
    13801 tttattatta taactgaacc gaaagcgttt gtaaaattta tctttataca ttctaagagg
    13861 tctgttgccc aataaaaaac aagagatcag acatgtattt gtctatcctc ttgtttaaaa
    13921 tagcaaaata ttcttgtttc ttctataaat ggtgttcaaa agcttttatc tacggcaatc
    13981 agtcttctca aatgtaaaac atgaggagct aattttattt gagtattctt tttgctcgat
    14041 gcaggacggc ttttttacaa cctctgattc atggtgttca atcagctgtc cttcggtatt
    14101 agctcaaaaa acggcaaaat atgaaaaact attttgccgt ttgtttctct aatactcagg
    14161 tcaaaccgct gatttcacaa cctctgtttt tattcattcg atttcaacgc atcaatcata
    14221 tcgatatgct ttaatttgaa atgggtaaca atcatcacaa taaccgtaaa tacgatagtt
    14281 aatcctgctg ataagacata agcccaccat gtgatcacta atggaaagat gacattctcc
    14341 atagacgctt gttgcaagat gaagtcagtc aatatatatc ctacaccaaa tcctccgatg
    14401 attcctaaaa gagtaaagat gatattttct cgaacaatgt acatcgtgac ttctttatca
    14461 aaaaatccaa ggacttttat tgtagataat tcgcgtacac gctcggaaat attgatatta
    14521 gttagattat acaagacgat aaaagccagc agtcctgata atacgacaaa gattaagaca
    14581 accgagtcta agttcgccat tgattcttct tgcgtttcga tttgtttgga catgaaagac
    14641 gtatttgtca cagcgtctgt ggcaagcagt ttctcggaaa gcatttcttc ttcttttgtt
    14701 gtcatcttat ctgtacgcag caaaaatgca ttatccatca tcgattgatc agtaactgaa
    14761 gcataatatt caggggacat ataaataaag ctacctagat agtttttcac gatttctttt
    14821 acttcgactt tccattcttt ttgatcttca tcataaagcg aaatatgatc tcctgtagat
    14881 aagtcaaata gttctgctac tttttgcgta atagcgattc ctgttttagg caaggagcgt
    14941 gggttctctt caagatcagt taaatggata aaacgatcca aatcagctgt tttacttggt
    15001 acgatcactg tcagactttg cgaagcatgt cctttttttc tcaattctac ggtttgagta
    15061 tgaatagcta ggatctcatt tactttttct tgcttctgca gcatatccgc tgctttttga
    15121 cgactatctt ccgtggatga atccaatgta acgattgctt gatagtcaat gatcgttcca
    15181 aattgtttgg ctgaaacaga acttagagaa tctttcaatc ccacgcctgc aaccatcagc
    15241 ccggcacatc cagcaattcc gataatcgcc ataagcattc ttgacttata tcggaagaga
    15301 tttcggtaac tgattttttg attaaagcta aggcgtgacc acagcggagt gatgtattca
    15361 agaaaaatgc gtttccctgg cttcggtgct ttcggttgaa gcaatgcagc aggccgttct
    15421 cttaaatctt tgaataaaac gatcattgca gcgccaaatg cggcaatgaa gaatgcggca
    15481 gctgcttgta aaatcggcgg ccagtcataa aaaataagcg cactcccaat atcataccgc
    15541 tcgttagaca gctcaaaaat gatccttggc aaaagattcg ttcctaatat cgttcctaaa
    15601 acaataccta tccctgaggc tagacttgca tagattgcat atttttttgc gatttcaact
    15661 ttcgtataac ctaacgcctt taatgtcccg atttccctgc ggttttcttc taccatacgt
    15721 gtcattgtcg taaaggtgat caatgcggca ataaagaaaa agaaaacagg aaaaacattg
    15781 gcaatcgcag cgatacgatc agacagatca ccaaattctt gaaaaccgac attttctgaa
    15841 cgttcattgt ataggtatga tggtttagtt aaattttcaa ttttttctgc atttcgattc
    15901 aattcttcct ctgcagaggc cagttcacgt tctttctcaa ctaattgcct ttcttgttca
    15961 gcaagttgag cttcttgttg agataatgtt tgaacagcga ttgttcgttg cgcttcagga
    16021 agctgctgga tagttgctga ctgttgcgct aactgttttt tagcatcttc taaccgtgtt
    16081 cttgcttgcg ttgtttgtgc tttgccatcc gctatttttt gctgtgccgg ttctaattct
    16141 tcgttggccg attttttcag ctcttctaag cgttcttcgg gtcgatcttg taaatacttt
    16201 tctgcctttt cttgattttg ctccatttta tctttgtaag ctttgctgta cgtattcaaa
    16261 ttctttacgt ttgtaaaatc aagatataag acagaataaa tatctgtttt aaaaacggat
    16321 tcaggtaaat agacaaaata atcgacgcta ccatttccga cgttcgcgta tcctctctcc
    16381 aaattgttga tgaacaatgg agaacggaca aagcccgtga tggtatactc tttttctttc
    16441 aattcatctg aatcaatctg ataaatatca ccgattttat acccttcatc ttccgctttt
    16501 tcatccaata caagctggtt tggtttttcc gggagttttc catcagttaa ttgtagcttg
    16561 ttctgcttgt tatttttgtt ataagaaaat atttgaatca cttcgttttt gccagtattg
    16621 gaataataga tctgttttcc tgtttctact tttgcatctg ggatcttttc tgcttgagca
    16681 atatcttttt gtgtcaagcc accagtagaa acgatttgca aatcagaaag tcctgctgta
    16741 ccaacatagt gatccatcgt tttttgcatg acaggtccag cagttttgac acctacaaat
    16801 aaaagtgttc ctagcatgac aataaggatg attgcaatga atcgtccttt agattgccga
    16861 atttcgcgaa aacctgcttt aagatatgtt cttgttttca taaaatcccc ctaccataca
    16921 atctcatcaa tggatgaagg atgatcattt aattcaacag accttacttt agcatcatta
    16981 atgtgaatga ctctatcagc gatgggcgct aaagcagaat tatgtgtaat gatcaaaacg
    17041 gtattgccgt gttgtctgct agcgttttgc aataatttca atacttgctt gcccgtttca
    17101 aaatccagcg cgcctgtcgg ttcatcacat aaaagaagtt tgggattttt agctagtgca
    17161 cgagcaattg aaaccctctg ctgttcgcct cctgataatt gggacggaaa gttattcaat
    17221 cgatgagcta ggcccacttg cctcaatacc tctacaggat caagcgcatc aggagaaact
    17281 tccgttgcca attccacatt ttcttttgct gttagattag gaacgagatt gtagaattgg
    17341 aaaacgaacc ctacatctgt tcgtcggtaa gcagtaagct gtttatctga aaattgcgca
    17401 atatctgtgt catcaataat gatctgacct tcatcaggtg tatccatccc acctaaaata
    17461 ttaagaatcg ttgactttcc tgctccactt ggaccaagta taatcactaa ttcgcctttt
    17521 tcaattgaaa aagaaatatc gtcatttgct gtaatggtcg tttctcccat tttgtatcgt
    17581 ttgtattcat tttttacttc gacatacttc actctgattc ctccattttc acgatatttc
    17641 tcgctatatc tatgcatcga atgcgttttc tcacacttat ttattttacc actgaatttc
    17701 tctagactaa agaaaggaat cctttaattt agttgacaaa taaacgattt atgatttact
    17761 tacataaaaa acattgttat ttgaaagaag gaacatcatg aatgatttaa aggaaaatat
    17821 gatttttgat ttatcaaaaa ctgcttttgt cgcgatcgac atgcaaaaag agatcgtaaa
    17881 taacggtaca ctctctccac acactgcagc atctattctg acaaacaatg atttgttagt
    17941 aagaacattg aaacgtaccg ctgccttgaa agttttagtg aacgtagaca tctccacttt
    18001 cccttatttg agtcaacaaa ctgatatggg tggaatgact gcttctgtac ctccagaatt
    18061 cactgattta cttttgaagg attctttgaa agatacagat aatatgttga ctatcacaaa
    18121 atacaatcca agtgcttttt ttggtacttc tcttgatctt caacttcgcc ggcgtggaat
    18181 cgaaactatc attttaagcg gtgtagcgac aacaaacggt gtatatgcta ctgcattaga
    18241 tgcctttcaa cacgggtacc atatcgtgct tgctgaagat gcttgcagtg atcgtgacaa
    18301 agaatcccat caattgttca taaaaaagat atttccgaaa actgcacgag tacgctcaac
    18361 gaaacaaata atcgaagcta tccaacaaag caaataagta ctggcacacg tgattttcat
    18421 ttacttcttt ttgatttcat gggaaaataa ccacaggatt tagataggag tatgaacatg
    18481 gtgaaaaaaa agatcacaat caaagaagtc gctaaacttt ccggcgtttc aatcacaact
    18541 gtctccttga tattaaatgg aaatacggag aaattcagtc cgaaaactgt tcagaaagtt
    18601 ttagctgcca aagaagaatt aggctatcag cctgactatt ttgctagaca aatgattacc
    18661 aaggaaacga aaacaattgg tgtactcgtt cctgatatca cgaatccatt cttcagtaca
    18721 ctgatgcgag gaattgagga tatcttgtat aagcagaatt tcgtcacgat attatgtaat
    18781 gctgattctg atcatcaaaa agaaatcgaa tatctagccg agctcacacg tcgaggtgtg
    18841 gatggattca ttatcgcgac ttctgctgtc tctacagatg caatcaacga aaatttgaaa
    18901 aaacaaggcc ggcccttcat tgttttggat cagaaaaaat ctgaaggatt tagtgatgcc
    18961 gtacgaacag acgattttcg cggtggttac ctagcgggca tgcacttgct tagtctagga
    19021 catcaaacga tcgcccttgt ctatcctgaa aatccaccgg aaaatgtcca cgctcggatt
    19081 gaggggttta aatctgctct tgatgtttac caaatccctc acgaccaact gatcctctta
    19141 cctacacagt tctcaaaaca aggtggctac cagatcacag cagaacttct tgattctgct
    19201 gcaactggtg tgtttgcttt aaatgatgaa ttagcttttg gattatatcg cggattagag
    19261 gaagctggaa aaagcatccc tgaagactac agcattattg gctatgataa tatagatatg
    19321 tgcgagtata tcaagccgaa actgacaacg atcgcacaac caatcttcga attgggacaa
    19381 acatctgcca agttattgtt agatcggatc caattcccag aaaaagaatg ggaagaaaaa
    19441 agattacctg tacgattaga aaaaagattt tcaactgcac ccttgaaata gctttcaagg
    19501 tgtgctatat ttttatcgaa ctattaaaac gttttactaa aacgttttaa aaaataattt
    19561 tcccatcaaa ataaatgaga tagttggagg tttgtaaaat gaacacggtt acagtaattg
    19621 gaagtattaa tatggacact acccttcgtt taaccaacat gcccaagcca ggcgaaacga
    19681 tgcatgcgca tgagattttt cacgctggcg gaggtaaagg tgccaaccaa gcagtggcag
    19741 ccaaacgttc aggcgcacgg acatctttta ttggaggcgt tggggctgac agcgaaggac
    19801 aacagttatt agatctactg acaaaagaaa acatcgatac atctgggata gctgaaatcc
    19861 aaggcgccac aaccggacaa gcaatgatta tggtagacgc agcaggagaa aatagtatct
    19921 tgatccatgc aggggcaaat aatgctttcc atgaacaaga agtcctaaaa aacaagcaac
    19981 tgattacaaa cagtgacttt attattgctc agtttgaaag tagcttagat gcgacgatcc
    20041 tagctttttc tattgcaaaa gacgcaggaa aaacaacgat cctgaatcct gcaccagctc
    20101 gtgaaacgat tcctactgaa ctacttgaaa agacagatat cattatacca aatgaaacag
    20161 aaacagaaat cattacagga atcagagtga cagatcataa cagtttggtc gcagcagccg
    20221 aaaaactcca tgaattaggt attggaacag taatcattac actaggcagt gccggcgctt
    20281 tctatcatac agaaaaagaa cacggtatcg tccctgcttt taaagtggat gccgttgaca
    20341 caacagccgc aggtgataca tttattggcg cattaagcag cacacttcag ccagacctta
    20401 gtaacttgaa agaagcgatc ctttatggaa atctagcctc ttctgttgct gtgcagtctt
    20461 atggtgcgca accttctatc ccttaccgcg aagctttaga acaatcagca gtctaaaatt
    20521 aacaatgaga ggaagaaaca aacatgaaaa aaggaaaagt aatcaattca gatatttcac
    20581 gagtaatcgc acaaatgggg cactttgata aattaagtat cggggatgca ggcatgcctg
    20641 tcccctttgg tactgaaaaa atagatttgg ctgtctcaaa cggtcttcca agttttttat
    20701 ctgttttaga aaacgtttta gaagaacttg aggtacaatc gattgaattg gcggaagaaa
    20761 taaagacaat gaacccggaa atattggaaa aaatcaaatt attgttacca gatacaccga
    20821 ttagctttat cccacatgaa gaaatgaaaa aagagttgaa taactgtcat gcatttattc
    20881 gtacaggcga aatgacacct tacgccaata ttatattagt gagtggagtg gtcttctaat
    20941 ggaaacgaca atgaatcctg aacagatggt actgtccgag cagattcata tgctgattga
    21001 acagttggga ggaaaagaca atattgattc tgtccttcca tgtgcgactc ggcttcgtat
    21061 caaattgaaa aaacagccag tagccaatgc agaaaaatta aaacagcaaa tcccttccat
    21121 taagtatttc attttactcg atagatatgc agaaataatc atggatcagg gattggctcc
    21181 tgcttacaag gaattgacgc gtcaaatcga tcattcagct ccgaaagaaa agctaaatcc
    21241 gatcgaaaaa ctatttggtt tgatatcgga aatctttacg ccgatcattc cgctgtttgc
    21301 cggttctggt atattaaaag gtctggttgt tttagcgact acgattggct ggcttagtga
    21361 aacaagcgga acttatcata ttttgtctgc tgcgtcgaat gccgtctttt attttctgcc
    21421 aatctttctt gctttttctg ctgccaaaac gtttaaagtg aatggatata ttgcggctgt
    21481 cattgctgca gcactgattg aaccgaatct gacctcttta ctttcagaca gtggcaaagc
    21541 agctactgat tttctgggga ttcctgtagt actgatgcag tatacgtcta ctgtcatgcc
    21601 ggcgatttta ggtattttct tttattcttt tgttgaaaaa ttcctcaaaa aatatattcg
    21661 cgaaaatatg caattagtat ttgtaccttt actttcatta gttatcacgg ttcctttgac
    21721 gttaatggta ttcgggcctg cgggtgttta ccttggcgaa ggtttagctg ccgcaattac
    21781 ttggatgatg gatattaacg gaccgatcag tggcgcaatc atcgctggtg gttggaatat
    21841 tttggtaata tttggtatcc aatgggctgt aaaccctgtc atgatcagta atatctctgc
    21901 ttatgggttc gaccgaatcg ttccgttgac aggagcagcc aattttggaa tggctggtgc
    21961 agctttaggt gtatttctgc gaagtaaacg ttcaaaaacc cgttcgatct ccggttctgc
    22021 ttttgcttcg attttacttg cgggagtgac cgaaccaact gtttacggaa ttgcgatccc
    22081 attgaaaaaa ccatttgttg ctgcttgcat tggtgcagct gctggtggag ctgtaatggg
    22141 atttgcccaa gtgaaagcga tcgcttttgt atttggtagt ctgaccacat tgcctgcatt
    22201 catttccggt acttttttct ggtacttagc aggactggct gttagtctag tcgtagcaat
    22261 gatcactact ctcgttagcg ggtttgatga agacctaatg tcttatgaat agttaatgaa
    22321 aaagactgaa gtatgagatg tttatcacat atttcagtct ttttcttttt aggatcatta
    22381 tttttataaa tttttgtgat actttccaaa ctttggtata atttacatat gcataaccat
    22441 ttttatcccc acttgtttat ccccaaacaa aggtggtcta tgcaataaaa tgaacgtcaa
    22501 agaaaaacga atgaatgctc gttgcttatt tacaaattgt tttatttaga atacacagac
    22561 agatttatga aaagaaaaag cttttcgaca cgattatctg ttccaaaaaa tgtctaatga
    22621 atgctgaata agacagaaaa tcaatgaaag gaaaaggact agtttattat gaaaaataaa
    22681 aaaacgatac gtttgctagc tgctacttgg ctgattgctc cgtctgtttt gtcgaccaat
    22741 accgtatttg ccgtagataa tcaaatagct gatcaaacag tcacaacaga tacgactaca
    22801 tccagctcag ctactagtga aacaacggat tcttttacag aagacccaac tggaacaact
    22861 aactcaacaa caggatcgac cgagccaact gaaattgatc cggctgatcc atcagaaaat
    22921 gaaaagccag ccgagacata ttcccttaca attgctcctt ctttgattgg taagatccaa
    22981 ctgactgctt cgacagcgga ttcccctgaa cagcaacctt tggatattac ggaaagtgga
    23041 acggtagaag gtttattagc ggaaacgaag gtaacttaca ctattacgcc agctgaaggt
    23101 gaacaaattg cttcagtcgc tgttaatggt gccaaagaag taaattatga tgcaaagacc
    23161 tttacagtag gtacgaacaa tttatctatt actgcagaat ttaaagctgg accggatact
    23221 tcaacagaga aaccaactga tcctagtgaa gaagtcccta gtacaccaga tccggaaacg
    23281 ccaaacaaac cagatgtggg taataacaac aataataatg gttcaaataa ttcaaacaat
    23341 aataacaata attcgaacag cgggaattct tcgaatcaaa caaacccatc tggatcgaat
    23401 aacaatggaa atactcagag agaaccaaac catccaaaca atggttcatc gaatggcgga
    23461 acgaacaatg cttcatctcg tccaaataca gcaaatcaaa gcggtataga gaatccatct
    23521 tctgcttctt ctgattttgt tgtaaaatca ccaattgatg ctgtattgcc tacaaataca
    23581 acgaatgtcc aacaagcaat cgttcgagaa gcattcaagc atcttggaaa accatatgta
    23641 tggggagcaa aaggtccaaa tacttttgac tgttctggtt tgacttatta cgtatatatg
    23701 aaagcaaccg gtcattatat cggtggctgg acaggcgaac agcaatatgc aggtacgcag
    23761 attccagtaa gtcaggccca acctggcgac ctcgtcttct ggggaccttc ttccggtgtt
    23821 actcaccatg taggtatcta tattgggaac ggacaattta tccatgcgcc tcaaccagga
    23881 gataaagttc gagtaacttc tatttcagat ttcacgcctg attttgctgt ccgagtaaac
    23941 ttagcaggtt tacctgctgc ttcaggttcg ctgacaggcg gctcatctat tttagatgga
    24001 ttagatggct cgttccattt cagtcaaaac caaacaactg atcagttctt gaaaaagatt
    24061 gcagatgatg cacaggaaat cgggcaaaaa gaaggaatct acgcatcagt catgatggct
    24121 caagctatcc ttgaaagtgg atctggaaac agcttattat caagcgaacc aaatcataac
    24181 ctttttggta tcaaaggatc atataaagga agcagcgtga ccttcaatac acttgaacaa
    24241 gatagttccg gacaaagcta ccaaatccgc gcacaattcc gtaaatatcc ttcttacaag
    24301 gaaagtttgg aagactatgc cgacttgatc aaaaatggac tgactggcaa tcctgatttc
    24361 tacaaaccaa cttggaagtc ggaaacaaaa gactacaaag aagcaaccaa atatttggaa
    24421 ggacgttatg ctacagatcg ccaatattca caaaaattga acgcgatcat cgaagcgtac
    24481 gacctgacaa aatatgatga accgaaaaaa gaagcagcaa caactgaaga agcaaacgct
    24541 gaaatcctca atatgtctaa gcgattcgat gtgccaatca aatggacaac agatggcgtg
    24601 ccaatcacag gattagaatt ttcaacgata aaacgcgtca acaacgcttc ttccatcttc
    24661 cgtgtcgctt caatctggga tttgtggaac aattttacgg caagacagat accagaaaca
    24721 actactcgta cagttaaagc tgcaactgtt cctgtactaa ccttgttaag tttagacaaa
    24781 tcattctggc ttgatctgcc tttaaagaaa tagaataaat taaaaagggg atgtgacact
    24841 gtcacactcc ctttttaatt tattctattt ctttatattt attttgtatt ccgttacaaa
    24901 ctcgcgtact tggttaggtt ccagagtgac atctccaaaa ctttcaagtc gctccgctcc
    24961 tggcagttct tgagtctcaa atgtgatacc gccatgattt actaatttat tcccgcgcat
    25021 ttccggtcca tcttctccaa aatttgctgt aaaaatcacg attcctgaag catctgtttt
    25081 tacttggatc gatacttttt catctgggct tgtcaattcc gcagcattta gtaaaccaga
    25141 ttgttttttc aacaaaaatg gatgatcgat gccgcccact atcattgatt ggcgaaaatc
    25201 actggcaaag acctcaccta attttttagg acgttggaag tcaaatgctg tgccacttac
    25261 tgaaactact tctcctgtag gcgttgtatc tttattgagc gtagcaaata atcggctatt
    25321 caaccaaagt atatgttcgt cgattgactg tgctggatca ccggttaaat tgaaatagac
    25381 atgatttgta ggattgaata ctgttttgcg gtcactgatc ccttggaccg tcactcgcca
    25441 tgtatcatcg ttcgtcagcg tataccgtac ttctacatct aaagttccag gaaatccgtt
    25501 ttccatatct gggctagtct gatagaaaat gaccgatgct tcgttttcac cattgatgac
    25561 tgtataatgc cactgcttgg cttcaaagct aggtgcacca ccatgtaaac aatgaccagt
    25621 gtccgggtct gtttttactt cgaacgtttc atcatctaat ttgaatgtgc cattcgtaat
    25681 ccgtccagcc atacgtccga ttgaagcacc gatataaggg tctttttcta gatattcttt
    25741 tgcttcatca aaacctaaga tcaactctcg tttttcatta tcgattattg tttgaaaatg
    25801 aacaacccgt gccccaagat cactgacaga caaagatgtc ccattttgat tcgtgatcgt
    25861 aatcaagtga tagttttcgc caaaattttg ttcattgatt tccatgttcc ttgcaccctc
    25921 ttttctttca tttgcactga ttccagcata catggaaacc gttttcttaa cagcttattc
    25981 cgtgagtaac gagaaaaaat ttactatatt ctaataaaag accgtgaaaa aaaggttgtg
    26041 acaaaaatat tgtcacaacc tctttttccg aacaaacggt gttcaaaagc ttgcatctgc
    26101 ggtaataagc ccaaccaaac gaaaaatatg aggagctatt tttgcttggc tgttcttatt
    26161 acttgatgca ggacagcttt ttcacaatct ctttttcaat acgattccag tatataacca
    26221 tgtcgtcagt acatagtaga tgaaatacaa tacgaagaat atcgtaaacg gaacccaaat
    26281 atctttgtat ggattttgca tgaatagacc aaacatttgt aatccgaata agacatggac
    26341 tacacctaag attcctggtg ctaagaataa cacgcctact tctctacgga tcgattgttt
    26401 aagcaacccg cgtcgtgttc ctatcttttc aagcatttca taacgagcaa tgtcactctt
    26461 gcttcctgac aagatcttga acatcaaaca gctagcaagc atggtcaaga aagctaaacc
    26521 taggaagaat cccataaatt caaaaccaga gaatagacca ttatacactt catacatttc
    26581 atatttctgg ttgctgtact ctactttttg caaagatgga ttgttcattt tattttgagc
    26641 aacaagtgtt tcgattggtt tcaggtttgc ttggaagtct tttacctgaa ctagctgtaa
    26701 agtggattgt ggcaagttca gttgatcaaa ttctgattga ctgactacct tgatttcttt
    26761 ttcttgctgt tccggcaatt catagcttcg aagttcctct tgtacagtca gttcattcat
    26821 ttttttagca ggaacttttt ctttcgtgat cttcggcggt gttccatctt catgttttat
    26881 catgatcaat ggttgagccg caaattcact tgcattatag taaatcgttc ccgcatcttc
    26941 tttttgagta taagaagcag aaagtgttgg tgaaagttct ttgatttttt gctgatcttc
    27001 tgcccgagga ttattcatca ctagatcata tccagaattg ttttctgtca agtctgcaat
    27061 ttcattttta aaacctaatc ctaccgtcaa agcgcccagt gccaaggcaa acagcatagc
    27121 gaccattgag agcatttgtg tatattcacg aatacgaaag tttaactgtg acaatgtgaa
    27181 attgttcaat tttttcaatg aaatctgttc tgatttcttt agtaatgata aaaagaaaat
    27241 gatcacagaa tggaaaatga aataagttcc taatacgatc gtaactaagg ctacccctat
    27301 accaaagact tgataggtcc ccacgtgttt catcatatag taaccgcagc ctagaaaagc
    27361 aattcccagt actacttcaa ggaaaaacaa gaatttatgc tgcttgattc ttgttggtgt
    27421 ctgatccgca cgaatcaatg ctaaaatcgg ttttttgaca atcgaaaaag cattgacaac
    27481 agcagctaat aaaaacaaaa cagcaaaaaa caaaacagtg atcaacaacc cgtgaatact
    27541 aaaaggtgta aaatgcgaaa tattgagatc taactgatcc actaataatc ggtggacgat
    27601 acttgtcaat cctacaccga cagctgaacc cactaaagta gctgcgatcc ctactaagaa
    27661 tgtttcagaa aaaatcatct gtgcgatttt tctgcctttt gctcccagca tcataaacat
    27721 tgcatagtct ttttgccgca tcgtcatcaa aaaggaattt gcatataaaa tataaacgaa
    27781 tgtgatgatc cctagtaaaa cagaaccgaa tcggaaaatg ataactgtag ccgcaacgat
    27841 cgtattactt ttcaaaaaag cttcgttgct tgccattgat tcaaacatgt aaaaaatagc
    27901 agatgccata actaatcctg agaataacac caagtagtct cttaaacggc tcttgatccc
    27961 agtaagtgat aatttccaaa gcatagtcaa tctcccccta ctgttccaag tttccaagaa
    28021 tagatagtat ttctcgatag aaggaatcac ggctttgatc tccacgtttc acttcttgat
    28081 ggataccgcc atccttgatg aataaaatac gttggcaata acttgcagaa aacggatcat
    28141 gcgtcacaag aagaatcgat acatgatctt ttgtattcaa ttcgtccatc gtatctaaaa
    28201 gatcccgggc acttttggaa tccagcgcac ctgtaggctc atcccctaat agaatcgttg
    28261 gttgtgtgat caatgcacgt gcggcggcga cccgttgttt ttgtccaccg gaaatctcag
    28321 aaggatagct ttccaaaata tgagagatgg ataaacgttc tgcaattttt tggacacgtt
    28381 gcttgatttc ttttggtctg acgccttgta aagaaagagg aacagcgata ttttcttgtg
    28441 ctgtcaagct ttctaataaa ttgaaatctt ggaaaataaa gccaatctca ttcgcacgaa
    28501 aatctgctag ttgatttcct tttaatgtgg tcacatcttt ttgattgatt cggatatgcc
    28561 catctgttgg tttatctaat gtggataaaa tattcaaaag tgtcgactta ccagaaccag
    28621 aagcgcccat gatcccaata aattcgcctt tttctacatc gaagctgatg ccgcttaatg
    28681 cttgcgtctt tttctcattg ttttttccgt atacttttgt tacattctgt acttcgacta
    28741 ttttgttcat ttctttccct accctttaat tagtttttcc agtgctgttt tcggcacgtc
    28801 ttttttttcg acttcttcat acgaagtgac acctttattt ttgttccagg tgatttttaa
    28861 atatgctcct ttacgaagcg gtcgagtcaa ttgtcccttg aagtccagtt ctttttcctt
    28921 accctctttc gtatagccag gcaggatata tctatagttg actgtttctt gtccagagtc
    28981 tgattttgaa actgtttttg taccatctgt cgtaatttgt acatagtatt cttctccacc
    29041 cataactacg taatctgcga ttttcacccc tgcaagtacc acaacgatga aaacaagtag
    29101 accgatcaga agttttttca ctttttcccc ttctctctta ctttatatac tgattataga
    29161 aaaaagcgaa caattctgcc ttcgaatcaa ctatcattct tctttcaatt ttgtcatttt
    29221 ctttaaaaca actaaaaaaa gagttcaaga caataatccg tcctaaactc cttcttccta
    29281 tcttacaaaa agtatgtcac ttacggtctt tcatgtcgcc tgtattgata acaggttgcg
    29341 ttcctttgtc tgtaatgatt gagacaagta aattattgat caattggact ttccgatcat
    29401 cggtgaaatt gatttcttgt ccatcttcga tttgctctaa ggccatttga gtgattgtga
    29461 cagctccttc aacaatggtt tgtcgagcag acaaaatggc ttttgcttgt tgacgttgga
    29521 gcatggcact agcgatttct gttgcatagg ctaaatggtt caagcgtgtt tcgattactt
    29581 cgacacctgc tactgctaaa cgctcttgca gctctttttg caactcgtca gacactgccg
    29641 tcgtgtttcc tcgaagcgtc aaatcattct cattgaatgt atcatacggg tattggctag
    29701 cgatatgccg aatggctgtc tcactttgga tttctacaaa atcttgataa tacgctacat
    29761 cgaataatgc ctttgctgta tcaacgactt taaagactac tactgctgag atttcgatgg
    29821 ggtttccatc caaatcattg acttttaaaa cagaactatt gaaattccga actttcaacg
    29881 aaacagtcat tttttgtgcc aaaggtatcg taaggaaaaa gccattttct cgaatcgtac
    29941 ctaaatattg tccaaaaaac aaaattactt ttgcttgatt aggactgact acagttgccg
    30001 aacttaacaa caataacgtg atcaaccaaa gaaaaatact taaaaaaagt gcccaaactt
    30061 tcgcttgcca catacctaaa tagaagaaaa acaatccaac taaagctaat acgaccaatc
    30121 cgacaatccc tgcataacca ttgatataaa atgctctttt ttctctcatg ctacttcctg
    30181 cgctccttta tccttcaata aatatctaat gttacttttt taattttttt ttcgaatacg
    30241 cgccattaca ccttctagtt ctaactcttt gtcttcagtg atgtaccaac cgcttgcctg
    30301 tgtccctccg gctgcctgcg gtaaataatc caattttgtt cgaacccagt gcttttcttc
    30361 tgtaaaatag tcttctacca agacctctag atccatccct gctgaaagag gcaaatcttc
    30421 ccgaacagat ttaaagataa atcgttcctt cttcccatca tacttcaata ttcctgtatc
    30481 gataatcggt aaagaataat aatccagctc tttcttcacc gtcaataaat gtttgaaaac
    30541 ttcatggtac acttgctcta attggcgacc ttctgaattg ttcgggtaat taaccatcac
    30601 tttttctttg tctggatcat agaaggtttg gcttagttga gtgatataag tatgtaatct
    30661 ttccatttct gtttttaact tttctctttg accttcttct accttcatat actctttcac
    30721 cctgttttct ttttagatat tttctttctt attttactat agttatgtgc gttaagcgat
    30781 gaaaaacagc aaagattgga aggatctttg ctgttttttc ttaaaatatc cagttgagta
    30841 caggatcaat ctgtttcatt gtcctcttga tccgtcgtaa tattgatcga tgtgtcttta
    30901 gcagtgatct ttagcttttt ctgtccttgt tctaacaaag tatttgttat tggctggtag
    30961 tctttttcaa tataagattc accagacgtt tggatagtat agccactgtt ttccatctca
    31021 tgcaaagata aattgccacc gtttaggatg acttttcctt ctttgctgat caaactgtct
    31081 tctagatgga agttgctgtt ttcacctgtg acgatcaagt tatccacatt ggcctcatct
    31141 aatcgaagtg agcctaattc atctttcgca gttattgttc ctcctgtaaa ttcattgaac
    31201 gatacccagc catcatgtgt cttagtattc acttttttga ttgatacttc gttgatatca
    31261 attgcactat tattcccttc gattgtcaat tcagataatt catgatctgc agggacaaca
    31321 atagtgattt gtgcacttgt gtcttctaaa ctaatgattg cacctgttga ttttttgact
    31381 gcattcacag tcaacacgcc atttttctcc tttatttctg gcttttctgt cttatcataa
    31441 gtcgttttta tctcaaaatc caatccgcgt atgaccgaaa ctgtttgatt ttctgcatgg
    31501 atgacgattt tgtttgcatc cttgattttt tttgtctcag taaccatatc gatcaaccga
    31561 ggaccattat cccaagtcag actcttttga gcgcctaatg tataagttgc acctgctagg
    31621 aggccaccag taagcatcag accaataccg gtaatcaaaa aatgtttcaa tctcaattta
    31681 tgtgtcctcc ttcaaacgcc cgctgaatgc agatctcttt ttgtaataaa acgtcgtccc
    31741 atccatttaa caaagttcat catgacataa aaaagccctt ttgttccttt cagcaacagt
    31801 ggcgaaataa atactgcgct tcctgtggcg aacagaccga caccgataaa gaataatcca
    31861 ctcagaatcg attgtccaaa cacactgatt cctgagatga tcatgaatag gccaacacct
    31921 aagatactga tacataaaac atagatacta aaaatgagcg ctagtaaagc aaccaatagt
    31981 cccccaataa ccaatataaa ccccagtgct agtggaatga ggacaggaga agcaaataaa
    32041 ccgataatga ttaaccaaac caggcgaatt tgtctttttg gatttttcac taactcgttt
    32101 tctgcttgtt cttcttctga aaagtaactg atttttaatt ttaaggcaaa ctgctttggt
    32161 gtaccatatt catcaatgat ctgatctaat gtttttccag aatctaaaaa atattcctca
    32221 taatactgga tcaaatcaaa acgatcgtct tcaggaattt cttgaagatg atccacaact
    32281 tcattcaaat attcattcat ttgtgctctc ctccaataac cggtctaaag aatctcgaaa
    32341 aacaatccat tcatcaataa tttcttctaa atgacgactt cccattggtg tcaacgagta
    32401 atatcgacgg tttctgcctt caaaaggttc atcataggtc tcaagatatc cttctttttt
    32461 caatcttctc aaaaccggat atagtgtaga ttcactgaca gagagacttt cttgtacgat
    32521 ttttgttaag gcatacccat acatatcttc cttgcttaat gctgctagca cagtaccatc
    32581 aagaagaaca gttggaatct ggatgtgcat tacgtcacct tctattctca agtgtaatat
    32641 tttatttcaa tctatattat acaacatata atatagtttc aaaatcagtt tgtcaaatac
    32701 aaaaaaactg actaaaagat ttgatccttt ttagtcagca aaaaatggct tctctttgat
    32761 ttttattata acagtggcat aatccaattt gtccacatcc agctcagtgg catgataacg
    32821 atcattgcag gtatcatgtc agctactggg aacattttca cgttgatcat tctaaaaccg
    32881 gtagcgacca tcaagaatcc gccgcaagct ttaaaatcta agatcatgtc tggtgtagtc
    32941 aatggataaa taaattttgc caataagaac aaaatataaa aaataatgaa ttggggaatt
    33001 gctatcacag aaacgacata ccctaaatta cacgcaaaaa tagctgctgt gaaaaaatca
    33061 aggacagatt tagaaatcaa aatcgtactg tctcctgtca tcccagaatc taaacttcca
    33121 tagatccccg taccacttgc acaaaataga acaatgaccg tcactaatgt gctgataaat
    33181 tcatcgtggg tcataccaag cttttcacta gggaagattt tagaaatagg tacttgcatc
    33241 agcgcagccc ccttatttat cccattacct aaatgaacaa tcaaaccaat cgctgttcct
    33301 atcactaaag caaaaataac agccggcata tttttcatcg gcgcaatgga atagattccc
    33361 atccccatcg aacacacacc aaaaaccatc gtcagctgtg ctttaaaatg ttcacttaat
    33421 ttatttccta ctaatccgcc aattagtccg ccaaacaaaa cggaacctac attgatcaaa
    33481 actccagttg gcatcaaaaa actcctctct ttttctacga agcgaaaaaa atcagaaaaa
    33541 tttctgtaat tattgctttc gctgcaagaa agattgtaac agacagagaa gattacacca
    33601 attcattttt tgtgttaaag tattctttat tggaataagt aggaggaata tgatggatat
    33661 ccataaattc gaagtttttc ttgatttagc cgaaacaatg aatttcacca aaactgctga
    33721 tcgacaattc accacccaag gaaatatttc taaacagatt ctttcgttag aaacagaatt
    33781 agacgtcaaa ttattcgaac gcgcccatag aaaaatcgaa ttgaccgaag ctggaagctt
    33841 attgctccca tatgtaaaaa atgtcgtaga acaataccat gctatgcaag aagtgcttga
    33901 aacctatacg aaagacaaca atctttcatt aaatatctta acgataccga caatgatcaa
    33961 ttataaaggt ttttccaaaa tcaccgagtt tttgaaacgc catcctgaat ttacagtcca
    34021 gttgaaagaa gtggaaagtg tcgaattaac ttacaatgac gccaatgaac atagtgacac
    34081 gatccacttt gctagaagtt tccaggcccc accaagttcg attgagtggt tgcctactga
    34141 aacagacgat tttgtagcag ttctacctaa aaatcatcct ttagctagta aaaagaaatt
    34201 ggatctaagc gaactgaaaa aggagaactt tttgctcctt ggccccacta cgaacttgta
    34261 tcaacctgta ctagatctgt gtcgcgaagc tggatttgaa ccaaaaatct cttataaagg
    34321 agcaagaatc gacttgatca tcaatatgat tgcaaatgac atggggattg ctattgttat
    34381 ggaaaaaaca gtcaagaatc tattaaaaga aaatactgtg attctcccta tttctccaac
    34441 aacagagagt tatcttgcat ttactcgtaa agtcggtgag cattctttgg cttcagatac
    34501 attttgggag tatttaaatc aagaagaaaa ctaagcccta cattttctgt ccatctatcc
    34561 acccaaaaaa agagagcgac gcatgacttt cgctctcttt cttgcatcat gtccttgttt
    34621 caatgacacc tctaacattt ctcgtagttc aataagaaag cagcgatttt tatgccaaaa
    34681 gaaccgtaag aacatttccc taatcacaaa aaaacgacta aaaaccccta aaaaccttca
    34741 atagaatttt taggggtttt attctttttc ctattgttta cttaaccgta tcattgctgt
    34801 cgttcctact ccttcgatac tgctataatc aatacgtcca tcatgcagtt ctagaatttt
    34861 tttaaccagt gaaagtccta gcccattccc agaaatttga cgacttgtat ctccttgata
    34921 aaatttttca aacattcgat ctctggtctc ttcattcatt cctacacctg aatcggtcac
    34981 ttccagtaca atctctgtgg ctgtctcaaa tagtttgata tgaatctgtc cattgatttg
    35041 attgtacttt atggcgttat ccatgatatt cagccacact tggtacaaaa actcttcatt
    35101 gcctgtgtaa tttactgcag caagttcgat atccaattct agctgttctt tctcccattt
    35161 aggctgaaaa aaaacgatta cttctctgat ttgttcatct aatcgatact ctttcttttc
    35221 cagttggata cgctggtttt ccagtttgtt caattttaag atgttctctg ttaattgtga
    35281 aagctgcgtg atactttcga taatccgata taaaaatatt tggcgttctt cgtcagagag
    35341 atttggggct tgtaacaatt gaacatatcc ttggattgtt gctagtggtg ttttgaattc
    35401 atgggataca ctggacacaa agtcattcct cagtgtctcg atactattga gttcttggac
    35461 cataacgttg aaatctttat acagttgctg tacttctgct actttctgct gttcatccat
    35521 tcgaatcgaa aaatctcccg ttgctaccag actcatattt gtccctagcg cactgattgg
    35581 atgcaggata cgccgcccaa caaaaatcga tattcctgta cccacgacca tactgaaccc
    35641 cgcaaagacg aataacgggt ataacgttgg ttttccagcc gattcagcag gcgagataga
    35701 atgtcgagac aataagaaaa taaaaccgag aaaacacagc agtgtcacta agatcgaaat
    35761 gaagacaata ctagcaaaat agatccataa ttgtgaaaat agcttttttt tcatctttaa
    35821 ataaccgcct tatagcctag tccccgtact gtgatgattt gaaaatcttc cgtcttttca
    35881 aaacgggtcc ttaaacgttt gatatgtaca tcgatcgttc gttcttctgt attcgtatct
    35941 aatccccaaa tatcatccat caactgttgg cgagtgaaga tcttgttggg ataagacagt
    36001 aatttataca gaagcagaaa ttctttttga ggcagaatca acgaatgctg atcttgtaac
    36061 actgtataag catctagctc taattttgtt tgtccgatta tcaagctact gctgtaattg
    36121 atctttgaac gtcgaagcaa tgcttccaca cgtaggatca tctcattgac atcgatgggt
    36181 tttgtcatat aatcatctgc tcctaatttg aacccgcgtt tcttatcctc aaaatcggcc
    36241 tttgccgtaa tcattagaac aggtgtgtca aatctggtgc tacgtaatga gtctagcaag
    36301 tcatagccat ccattttcgg catcatgata tctgtaatga ttaattctat acgtgtcgct
    36361 tctagttttt tcagcgcatc ctctccattc aatgcggtga tgactgaaaa gcccgctcgt
    36421 tccaacacag aacggtaaag caactgtaat tgcggatcat cttctactac taaaatacga
    36481 ttcattgatc tccctctgtt ttttgaaaaa tttctagatt ttttcttgta gttcatcttc
    36541 agttaacatt tatttcgtat actacgatca ttgttctgat atacttatta gtataccgaa
    36601 tatttcaata cgggagaagg gtgattatgc ttcaattaaa agatataaaa aaatattata
    36661 aagtcggcga aaccaccacc aaagcattgg atggtgtgtc tgtcgctttc agacaaaaag
    36721 aattcgtagc gattttaggt cctagtggtt ctggtaaaac gactatgctg aatgtgattg
    36781 gtggactaga taattatgat tccggtgata tggtaatcaa cggaaagtct actaaagact
    36841 ttaaggacag tgactgggat gcctaccgaa acaactctat cggtttcatt tttcaaagtt
    36901 acaacttgat tggtcatcta ggcattattg aaaacgttga acttgggatg acattaagtg
    36961 gtgtttctaa agacgaaaaa cgaaaacggg cagaagatgc attgcaccga gtcggcttga
    37021 caaatcatat gcataaaaag ccaaatcagt tatctggtgg acaaatgcag cgagtggcca
    37081 tcgctcgagc actagccaat gacccagata tccttttgtg cgatgaacca accggagcgt
    37141 tagatacaga aacaagtatc cagatcatgg aattgatcca agagttatcg aaagaaaaat
    37201 tagtgatcat ggtcacacat aatcctgaac tggcccatca atacgcagat cgaatcattg
    37261 aattttctga tggtaagatc ttaacagatt cccatcctca catcgaacga ccaaaagatg
    37321 atcaatttaa cttacgcaga acaaagatga gtttttggac agcgttaaag ctttccttca
    37381 acaatatccg aacaaaaaaa ggacgtactt tcttgacctc ctttgcttcc agtattggga
    37441 tcatcggaat cgcgatcgtt ctgtcccttt cttctggatt ccaaaaacaa atcgataaca
    37501 cgcaagctga aacgatggcg aaatttccga ttactatttc taaggtaacg actaaccaga
    37561 ctcgtgacga tgccggattg ggtgcaagca aagcggatta tccagacagc aaaacgatta
    37621 ctgcaaaagt cagcgaagaa gataaagcac agcacacgaa taagattgat caaacatacg
    37681 tcgattacgt aacagacatc gatcctaact taagtaataa tatcggattt acccgtacta
    37741 caggaatcaa tcttttacgt gatgtaaatg gcaaagtaca gcctgtcagc ttctcgaatc
    37801 aaaatcctga tacggaatct ctttctttat ctagtacgat gtcagcaatg acaggtgtgg
    37861 gagtgtcaag tttccctaca cagcttgaca ctagcaaaga aaacttttta aaagacaatt
    37921 attctttact tgccggaagt tatccagcct cagcaacaga tgtcgtgctg atcgtagacg
    37981 gcaataataa tactaatatc aacgcattga agaatcttgg atttgatgtg aaagaagacg
    38041 aaaaacttga ttttgatgat atcgttggta caacattcaa attagtaaac aacaatactt
    38101 actatacaaa acttccaact gggaatttta tccctaatac agattatgat gcgatgtatc
    38161 agaatgcttc tgatgaattg aagatctcgg ggatcctacg cgtgaaatct tcttctacaa
    38221 tgaatctctt atctccagga atcgcttata gcgatcaatt aacgactcaa atcgtcaacg
    38281 aaaacaaaga atcagaaatc gtcaaagctc aaagagacag tggtgtaaat gtcttaacta
    38341 ctgaaaaagt tgacgaaaat gccaaacaaa cattgcttag ttatttaggt ggagacagct
    38401 tgccttcaag tatcatgatt tatccgaaca attttgaaga caaagaaaag atcttggatt
    38461 atctagatga ttacaataaa ggcaaatcag atgaagataa aatcatttat actgatttag
    38521 ctggaacgat gactgaactg actggcggat tgatggatgc tatcacttat gtccttattg
    38581 cttttgcagg gatctcttta gtaacaagta tgatcatgat cagtatcatt acttatacat
    38641 ctgtgattga acggacaaaa gaaatcggtg tactaaaagc tttaggtgca cgtaaaaaag
    38701 acatcactcg cgtatttgac gcagaaacgt gtattttagg tatttcttct gggatattag
    38761 gtgtgtttat tgcatggcta gctacgttcc ctatcaatag catcttatac aacatgacgg
    38821 atctaaaaaa tgttgctcaa ctaaatcctg tccatgcgat tattctagtg atcgtctcta
    38881 ctatattgac gatgcttggc ggtcatcttc ctgcacgaat ggcagcgaaa aaagacgccg
    38941 ctatcgcttt gcgtgcagaa taaggttgtg acaaccacat ttagatttga gtcataagag
    39001 cgctgaaata gtagaaaaca gcaagaaacg aggaagtaat atgttccttg tttcgcgctg
    39061 ttttttttaa ttatttttta taattctggt atacttttct ttcctttgta ccacaactct
    39121 tctggcgtat acctgtcttt tccatttatg aatactgttc catctgcttc aatcgttact
    39181 tcagtcccaa tccacatatt acgagaaagt gcgagaagat tttttctttt tcctcttcct
    39241 ttttttccaa attgcaaggc atcggttatc tcttctgtcc aatgagattt cacgtatttt
    39301 acttctccgt tttcaaatgt aactttcaaa atattcgcta tattttccac ttttactgct
    39361 ttaggaaatg actcctccat ttttttcact ttccttcctc caacactaag tatgcgcttt
    39421 cttttagtga taagtatatc atagtttatt ctattatcaa aaaaacgcat ccattccatt
    39481 gtagaatact ttaccgaaca agttgaattg ttttcctctt tttcaccttt tactatagat
    39541 aggtaaagac aactaaggag gaatctctca tgacagatca accgtatgat ttaagaaaag
    39601 tcatcgaaga actaaaaaca cttccaggtc aatatcacga aacagatatt gaaatcgatc
    39661 ctgaagcaga attatctggt gtttaccgtt atatcggtgc tggcggtaca gtaaaacgtc
    39721 cgactcaaga aggaccaact atgactttca acaatatcaa aggtttcccc ggcacacgtg
    39781 tgaacatcgg aacaatggct agtcgtaaac gtgtaggtga aattttgcac catgattatc
    39841 gaacacttgg tcgtttcttg aaagacgctg tagaaaatcc aatcaaacct gtgaaagtag
    39901 acaaagcaga cgctccagca caagaagtcg ttcatctagc taccgatgca gacttcgata
    39961 ttcgcaacat tttgcctgca cctacaaata ctcctgaaga tgctggtcca tacatcacaa
    40021 tgggtgtagt cttaggatca gatccagaaa aaacaatgag cgatgtaacg atccatcgta
    40081 tggttctaga agataaagat acgatcggta tgtacatcat gcctggcgga cgccacattg
    40141 gtcacttcca aaaacaattc gaagccttga ataaaccaat gcctatcact atcaatattg
    40201 gtttagatcc agcaattgcc attggcacga ctttcgaacc acctaccact ccacttggct
    40261 acaatgaact atggtgtgca ggagctttgc gtaacgaacc tattcaaatc gttgatggta
    40321 tagcagtcga tgaagtgggt attgctcgtg ctgaattcat cattgaagca gaaatcatgc
    40381 caaatgaaac aatgcaagaa gatatcaaca cgaactcagg aaaagcaatg ccagaatttc
    40441 ctggctatac tggggatgct aatccagctg tacaagtagt gaaagtcaaa gcagttactc
    40501 accgaaaaga caatccaatc atgcaaacaa cgattggtcc cagtgaagaa cacgtatcta
    40561 tggccggtat tcctacagaa gcaagtattc ttgccttggt cgataaagct attccaggaa
    40621 aagtagtaaa tgtctacaat cctcctgcag gtggtggtaa attgatgacc atcatgcaaa
    40681 tccgtaaaga aaacgaagcg gatgaaggta ttcagcgtca agcagctatt cttgctttat
    40741 cagccttcaa agaattgaag acagtcattt tagtcgatga agatgttgat attttcgaca
    40801 tgaacgatgt agtttggact ttcaacactc gtttccaagg agataaagat atcatcgtga
    40861 tcccaggaat gaggaaccat ccattggacc catcagaatt accagaatat aatcctggct
    40921 ctattcgttt ccgtgggata agtgcaaaaa ctatctttga cggtacagtt cctttcgata
    40981 tgaaagaaca ttttgtacgt gcaaaattcc aagaagtaga agattgggaa aaatatttga
    41041 aataatgaat gatctgcaac tgttttgaca tcataaaaag gagtgcggaa aatggaacaa
    41101 ttggcacaac ggaagaaaaa aatcgtgatt ggtgtaagtg gcgcttcagg caccatttat
    41161 gccatcaacc tagtgaagaa actaaaagaa tatccgatga tagaaacaca cggaatcatc
    41221 agtccatggg caaaacagaa cttaaagctg gaatccgact tatcactaac tgaattcgaa
    41281 agcctgtttg attaccatta ttcaaacaaa gatttaggtg ctgctgtcgc cagcggatca
    41341 tttttgaccg atggaatgat catcgtaccg gcaagcatga aaacagtcgc aggtatctct
    41401 gttggtttag gcgacaacct gattgcacgt gctgctgatg taacaatgaa ggagcaacga
    41461 aagttagtca ttgttcctcg tgaaacgcca ttaaatgcca ttcacttgga aaacttgact
    41521 aaattagcac gactaggtgt gcaaatcata ccaccaattc ctgcttttta taatcagcct
    41581 caaacgatcc aagatcttgt taatcaccat acaatgaaac ttttggatca atttgaaatt
    41641 gtaaatgagc attcaaaacg ttggcagggt gattaatatg gaaaaagaaa cgatagttga
    41701 agtaaccaaa ctaggtttca cgatccaagc tgctgttaaa gtaatcggta aagacttatt
    41761 gatcacttta acaggcggag atacaccaca tatcggaaca gtcactacat tttctcgtga
    41821 tacagagatg caaactgtac gtttccctag ccacgatggt cggttccata aagacgatgt
    41881 cttagccgaa aaaatagctg tgatcatcaa aactgccgtt ccgggaagtt gtacgatcac
    41941 ttccggtatc catgttgacc atatctccaa tgcacaaatc aacgcctctt ttccgatgtc
    42001 agaagagtta ggttacaaga ttttagattg gttggaaaaa atagatttcc atatcaaaga
    42061 accagtttat tataaagatg gtgaaaaacc attatgaaag aagaggttgt gaaatcagcg
    42121 ttatgacctg agtatgagag aaaaaaatgg aaaaatagct tctcatattt tgccgttttt
    42181 gagctaatac cgagggacag ctgattgaac gccgtttatc aagaggttgt gataaagccg
    42241 cttcgtttcg agtagtaaga aaaattttgt aaacatgggt ttccacattt ttgcataaat
    42301 ttgacttact accgagaaac tggcttttga acaccgttta tcaagaggtt gtgacacgtc
    42361 ttttgtcaca acctctttta tttttgcttc actgtaactg ctacaatatc accgatttct
    42421 tttccgatgt ttttacgaat atcttttcgt agtccaagga tgtagcagac tgaaccatct
    42481 ggatttttca cgcccatatt cacgatactg ccttcatatg gcacattgtc aaaagttgct
    42541 tggactttaa ctcttccagc accgaattct tttcttatat catacggaaa aataatatat
    42601 gccccgccct tgccgacttc ggaagcatag atttttgatt caaaagaata aatttccctc
    42661 attttatttc tcctattttt tacatctagt atagcatagc aaaaaaaaga aggaactgtg
    42721 acaaaagtct tgtcgcagtt ccttttttcg aataaacggt gttctcctgc caactcctcg
    42781 gtcacaagtc acaatagtca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    42841 ctcagagtta aacggcaggc tcacaacctc ttccttaaac ggtgttcaaa agcttgcatc
    42901 tacggcacta agcccaatca gatgaaaaat atggagtgct atttttatct gattgttctt
    42961 actgcttgat gcagagcagc tttttcacaa cctcctacat ggtgttcaaa atattattcg
    43021 ccttttgctt ctttcactaa ttttgcgaat gcttgttgtt ggaattcagc agctaaggct
    43081 ttcgtacgtt gttcttgctc tgctttgctc atttttggat tttcagtcat tgcttttacc
    43141 ataccgtctt gaacataagc ttttgcttca ctttccatcg tactttgctg tttcttcact
    43201 aattcagcta acttggctgc ttggtccgta cttaattcta cccatgtctc tgggattttg
    43261 aatgtattca ctcggctgtc atattcgtga ttgttatcag caatattgaa ccagaattta
    43321 tacatgtcgt ttttgtattc ccaataagta gttttcgtca ctttttcagc atcgccgtct
    43381 gtcttttcta ctttatttgt ttcgttatcc gtaccagttg cttttggttt ttcttgtttt
    43441 tcatttgttc ggtaaagata cactttttct tttccattcc ctaaagcttt atacaaaagc
    43501 atatctgctc cttgggaatc agcactggaa acaatttttt ctgtttttgt ttccgttact
    43561 ttttccattc caaagtgatt ggacaaatta gcgacgatca aacttagtga agcgacgaag
    43621 attagtccga aaatcaaaga taaaaaggtt tgccatgttt ttttagcgaa cacgttcgtt
    43681 aaagcaaaag caagcaagct gacaatcaaa actccaataa tcatgcatta tcccccgctt
    43741 tcattagaac aggttctttt ttcttcaata aaaaggcaat aataaagcca agaatcccaa
    43801 agatgatcgc tacgataaac gcggcatggt aacctgacag tgtggcattg attgcctgat
    43861 ctttataagc taatggcgta ttatccaata cagatttgct tgggatattt gcttttgtca
    43921 cattcgtcaa cacactgatc aaaatagctg taccaatcga gcttgcgatt tgacggaatg
    43981 tattatttac cgctgtccca tgactgatca agttatttgg caatgcattc ataccagaag
    44041 tcgttaccgg catcatgacc atggagatcc caaacatacg gatcgcataa aggatcacga
    44101 tatataaaac tggagtcgtt tttgtcaaga aagcaaatgg tgcagttgcc gctgtcaaaa
    44161 tgaacatccc tgtgatggct aaacgtttcg cgccgtattt atcgaaaatc gcacccgtca
    44221 caggcatcat agcccccatg atcaatgcac ccggcaacaa catcaagcca gaatggaatg
    44281 ctgattctcc acgaatattt tgaatataca atggtacgac catttctgcc cctaccatcg
    44341 ccatatttgt tacaccagct aaaacagctg caatcgtgaa tgtagatgat ttgaatacac
    44401 gaagttccaa gaatggatgt tccaaatgta attgacgcca tgagaacaag gcgatgaaaa
    44461 tcacaccaac aactaagaaa ccaattactt tcaagcttcc ccagccgtca tctcctacac
    44521 tagaaaatcc gtaaagtaaa ctaccgaatc caatcgttga taaaatagcg gataaaatat
    44581 caatgctagg atttgacaat ggaataacac ttttcattag gaagaatgct aaaaccaaga
    44641 caagaacaac gattggcagt accataccaa acaagtcacg ccaatggtag ttatcaatga
    44701 tataaccaga taatgtaggg cctaaagcag gagcaagtcc aataacgatc cctgacatcc
    44761 ccattgctga tcctcttttt tctggcggga aaatagatag catgatattt tgcaataatg
    44821 gcatcgatac tcccacaccg caagcttgga tcaaacgacc gattagtaat gtactaaaat
    44881 taggtgctgt aaagcaagta atcgttccga tcaaaaagat cgtcatggca gaaagatata
    44941 aatttcttga actgaattta ttgatcagcc atgctgttat tgggatcatg atcccgttga
    45001 ctagcaagaa accagtcgtt aaccattgca catcagacgc tgaaatatcg aaagctttca
    45061 tcaatgtagg aaaagctgtc gtcaataagg tctgattcaa aacggtacaa aatgtaccaa
    45121 ttaataagac aacaactaaa agtgtccgat tatatggttt tccgtaaata tctacgggtt
    45181 ggttgttact catatttctc cttctttctg aattttttct gaaactacta gaatacttta
    45241 gtcctaaatt cgctatttgt caacctactt gacacataag ttaatacgga tataattaag
    45301 ggaagcaaga ggacaaaagg agtgacaaaa atggttgggg cttcccttaa acgtttgttg
    45361 gaaaatgatc aattggttgt tggcatcagt gaattaagtg atatcgtagg tgtgtctcca
    45421 cgtcaattaa ggtattggga acaaaaggga ttcattcgtt cgatcgaagc tgatgcgaat
    45481 tgtcctagaa aatatcgttt acctacagtc ataaaagtag aactgatcaa aaaatattta
    45541 gatgacggat ttactttgtc aaaagctgca gaaaaggcag aaatccgcca aaagaaaatg
    45601 caccatgtcc gtaaagtttt ttcaaaagca atcaaagata tcgaattgat cgacgaacgc
    45661 tatacgattt tacaaatcgg taacttcaaa gaagagaatg ctaagatgta catcattcat
    45721 gacaacgaga cagacgaatt aacttacaag ctccttcctg tcgatgaaaa agctgactac
    45781 gaacagttgt taaaagaact ctaaacgcca ctaatctcct aagtaccaag ctttttaata
    45841 agtagatgct acataaatac ttgaaaaaag gcctgtttga acataagaat atccgaacgg
    45901 tgatctgcgt ttctttcata tagaaaggaa ttctccatca ctgttcggat atttttttat
    45961 ttttttcggt tactttcttc taatacatct gttagccaat ttgcatattc tgtttcccga
    46021 ttgatcgcat gcgctaaaat caggtagtgt ccgtaatttt catgtttttc tttttcagta
    46081 ggaaagatcg ttttttttcg ctctaataga tgaagtcgtt tttcttcatg aaggtcacgc
    46141 tgctgctgaa taatttctac taatgccgga tcattcacgt ctttgacgaa atacaatttc
    46201 agaacaaatt cgtctcgatt aaccggtagt tcattggtgg gtgtatgaat ccactctgcc
    46261 aattgttcct tcccttcttc tgttaattca taaactttct tttccaattt ttcacctgtg
    46321 atctctactt gatgctgaat gattccttgc tcttccattt ttgcaagttc aggataaatc
    46381 tgactatgtt ttgcttgcca aaattctcct atttcatttt tgaacgattg attcaattca
    46441 tatcctgtca tcttcttctt acttaataac cctaacaaaa tatatcgaag tgtatttttt
    46501 cttgccatca gttttccctc cttgacaaat ctttaaatcc attctatcat aaatgagtaa
    46561 tcgaaaacat gtagtttatt acatgtttta atttataagg agatgcttaa acatgaaaga
    46621 atttaaagaa ttggaagatt ttattggaac tcactttatc tatacgtatg acaatggttg
    46681 ggaatatgaa tggtatgcca aaaatgacca tactgttgat taccgtatcc atggcggaat
    46741 ggtcaaaggc cgttgggtaa aagaccaaga agctgatatc gttaaattga cggacggcgt
    46801 attcaaaatc acttggacag agccaacagg gacagacgtg gcattggact ttatgccaaa
    46861 tgaaaagaaa cttcacggaa tgatcttttt ccctaaatgg gttgaagaac atccagaaat
    46921 cactgttact ttccaaaacg aacatatcgc agaaatggaa gcagctcgtg aaaaatatga
    46981 aacttatcca aaattacttg ttcctgaatt tgctacgatc acttatatgg gtgatgcagg
    47041 tatagacaat gaagatgtta ttagcgaaga accatacgat ggaatgccag atgatatccg
    47101 tagcggaaaa tacttcgatg aaaattataa acgagtaaaa taaggttgtg aaagagaggt
    47161 tgtgaaatca gcgttctgac ctgagtatta gagaaagaaa cggaaaaata gttcctcatg
    47221 ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tatcaagagg
    47281 ttgtgaaatc agcgttatgc tttgagtaat aagaacgcta gttagaaaat agcttttcat
    47341 attttctagg ctagtgggct tattaccgag aagcagccgt ttgaacaccg tttatcaaga
    47401 ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaatggaaaa atagttcctc
    47461 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttatcaaa
    47521 gattgtaaca actgcatatt cacacagtta aattagtgac ttcaaaatga aataatgctc
    47581 ccagcaaaaa attaggctgg gagcattatt tcgttattct gttcatcaaa aatcagcgtt
    47641 ttgattccat ttcatcacaa gttcctcctc atttactgct tcatcttttt gctgtgtttg
    47701 aattgtaaaa ccttgtgaaa gatagaaatg aatagctgat tgattttttt gatagactgt
    47761 caaagtcagt gttttattgg tttcttttat ttttttcatt agttgcgtac cgattctttg
    47821 ttgccggtat tcccttttca caaagattcc tgcgataaac tgatcaatca ccccagcaaa
    47881 accaataatt tcttgatcta tttctgctaa gtaaatcact gcatctggta aagctttcct
    47941 aacagattct acttgattct cccaataagt tgatggaatg aattcatgag aatccaagtt
    48001 agcatgcagc caaatcgata gaacagattc cagttctttg gcagacaatt ttgttgttgt
    48061 gcggatcatt ttttctctcc ttacttattc attgatttta aaataaaaac catttttttg
    48121 aagctctttt acaagttttc gcccctcaaa aaagtatatc ttctcttgtt ttacttttct
    48181 aataccaaaa gaaacagcaa ctttaggatc atcagctgaa acgattcgat aagttccacc
    48241 aggcaattga tccagcttga ctttcccatg atggtcgctt tgtactgaaa acggcacacc
    48301 atttctagta agtgtttttt tcttatgttt caaaatgaat gaactaccat ttaccggttt
    48361 ccctgacgaa tcactaataa taaatgaaaa atcaagcact tttttactta atctatactg
    48421 atagattagt cgtccgataa acactaacag tatgactaca gctattatcg ttcctgcaag
    48481 aataaaccat tgccgcatgg ttctttcctg atttcctttt ccttcttctt tttttaccga
    48541 ttcgttataa ggaatccgat gtcctgtcac tagcaaacga tgcgtgttga tcatatacgg
    48601 cgtacatgta agcaaggtaa ctaagtcttc tccttctgaa atcgttagaa cagacgtgtc
    48661 atctggcagt accacttgta tatttttaac ttgataagcc aatttctccc ccaaaacagt
    48721 caaaataaac gtgtctccgt tttctaaacg atctaattcg gtaaataacc gtcgattagg
    48781 taaaccgctg tgagcagaga tcactgaatg cgtcgaattt ccaccaagcg ggaaagaggt
    48841 tccttgcaag acgcctgctc cattttcaag gatcctacca ttgagccgat cataaagtga
    48901 aatatttaat tggatcttag gtatattgat acttccgatc agccattcct ctaattggct
    48961 ggatgttgta ctttcatttc tgttcttttc attgaaagga tcagtaccag gattgaatcc
    49021 ttggtcagtt aatcgttggt ttttctcctc cattttcttt cgctgcactt caatttcagc
    49081 tgcggtccgt ttttgtactt gttcgatacg tttttgatca ataaaactat ttaaagaatc
    49141 cacataaaat ggatataaag cgatcagtaa ccctacgacg atacatatta ataaaaacaa
    49201 acgaaacaaa agtcgacgag actgtttttg cttactctgc ttcacatgtg tcctcccttg
    49261 caagtttttt tgttctttct tttattatat gggttcagga aaaaaataga aaatgaaagc
    49321 cgatgaggtt gtgaaaaagc tgtcctgcat caagtaataa gtacagccca aaaaaatagc
    49381 tactcatatt ttttgttggg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    49441 taaggaagag gttgtgaaaa ctgcgttatg ctttgagtaa taagagcgct agtcagaaaa
    49501 tagcttctca tattttctag gctagtgagc ttattaccga gaagcagctg attgaacacc
    49561 gtttaccgag aggtcatgaa aaagctactt tgtttcgagt attaagaaaa attctgtttc
    49621 aaaacaagga gatgcaacaa aacttatgtc gcatcctctc tccttagaac tttcacttat
    49681 gtttttcttg taaaattcat aaatattttc atgaattttc taatttcttg cctacctctc
    49741 gcataggata tatgatgaat ttatctaaag tttgcaaagg agttcgacaa ttgaaaaaat
    49801 atggcccatt tttagcaatt tttttcattg ctttggcatt tctcatgcct catttattca
    49861 cacataaact aattttgggt gctgatgccc cattccatta caatcggttc tatgatgccg
    49921 cgcaacaaat taaatatggg gatttccatt attttccttc cctttatgga ttccagcaaa
    49981 gtggcaggat cgtgaatgcc gtttacggcc catttttcgc ttatttacaa ggattgatcg
    50041 tgttgcttgc aggtagctgg tttcattatc agattctttc aaatttcatt ctttatctta
    50101 tttcaggatt ttctatgctg attttactga gatatgtcaa tgttcgaaat tgggtaagtg
    50161 taccagtagc cgttttattc atgagtacgt attctattca atactggtct atcaaccaag
    50221 gattcactag ctgggggact tgtttttatc ctttatgtat gatccctatt gctgatttcg
    50281 tccttcataa aaagttccct gttatcaaag tcgctgtctc agtgggactt atgacacaga
    50341 tccatttact gtcttcgatc atgttagctt tgatgtatat ccctttttat ctttattact
    50401 tttttaacca gactgaaaaa ggaaaagcac tgcttcaact gattaagtcg gtcttgcttt
    50461 attttgttct gacagcaaat atttgggcag gattagctat tgtttacagt gggaataaga
    50521 ttcttcctcc ctttgttaac agagaaatga gtcaaaaggc gatagatctg gatggcagtt
    50581 attggctcca ttaccctaag gcctttccta tattgatatt atcaggtttt ttgcttttta
    50641 ttttctttca acaaaagaac accttattcc aaaaaatcgt gttgtacaca agtcttgttt
    50701 tcttttttct ttctactagc ttgattccat ggacgacatt gatcgaaaaa aatgtgcctt
    50761 ttattagttt gatccagttt ccatttcgat ttttcgtgcc atttacgcta ttgcttctac
    50821 tttaccttgc cctttcactg aaccagtggt ctgaacaaaa gtggttccgt cttttaagta
    50881 tatttggcat tcttattttt tcagcacaga cgatccagaa cttataccag catctggaaa
    50941 agtgggaaaa tgaaacattt gtcagtcgac atacttatct attcgatacg ccggaagaag
    51001 caaggaaaac attcttcagc aaagatatgt ctaccagctt gttcgttttc caaaaaacca
    51061 cacctgacta tctgccaatc tataaggaga caaaagacaa taaatacgac cggtataacg
    51121 aagaaatact agaaaacgaa acaactttta taaaaacaca tccaggcggt cttttgacaa
    51181 tcaagtggaa aaacactggg gacaaaactg ttcatatccc tgttatcgtc tacgatcgga
    51241 ctgtgctaca gcaaaatgga aaaacattga ctgattatga agtaacagat atcgggaccc
    51301 caatcgtgaa gcagcaaaaa ggaatcaacg agctcacgct tcattatcaa acgccaatct
    51361 atttctattt cattctttct cttactttga ttggctggtt taccttgcta tgtttattta
    51421 tttatcatag atacaagctt ttacgtgctt aggcaaaagg gataaataca tccgatcaaa
    51481 aaactctcca aacggtataa tcgtttggag agttttattt taatcagttt ttttatgtta
    51541 tatgttatat tttttattcg ttcacatcta attcgatttc caccccgtag tgatcactga
    51601 tgattggact atcgatccca tcaaaaatcc gttgatattt tttaacctgc attccttcag
    51661 ggacgaaaat aaaatctata cgcaattttt ctgtattttg ttcccaacca tctattttct
    51721 tttccacagt agctgctttt cctttttcat tcgcgacaac atacgaatct tgaagaagaa
    51781 ggcaactttc tcttacagta taataacctt gagagtctac tggattattg aaatcaccta
    51841 ggaaaaaaag tggtacgcga gtttccaaaa agtagttttc caagtttttc cactcaaaat
    51901 aaaagccact ttttttatct gtccaccaag aaaagtggca gctcgagaca aaaatgtcct
    51961 gatcatctat ctttgttttc ccaatcaaga tcttgcgtgt ctgataatct tctttctttt
    52021 gaaattggga gacggtaagg acctgacttt ccaatgtttt tttcgtaagc agtgcatttc
    52081 cttcttcata tttatcataa ccgatgtggc tcatttccca actccaaaaa tactcttttc
    52141 cgtgttcctt taaaagctga actaaacggt aggcaaaatt atctttacgg ataggtactt
    52201 gattctttac cggacagaac ttcattagct tcgcaggttc tacttcttca gattccagta
    52261 attggttgat ttcttgtaaa gcaatcactt cataatcttc taacaggatc ttatctgcta
    52321 attcttgcaa ttttttctct ggttctggct caagccagct atgcgtgttg agtgtcatga
    52381 atttcattgg ttttctcctt gtcttcattt cgaaacaaaa gggttgtgac aaaatttttg
    52441 tcacaacctc tccagcaaat agtgttctcc tgctaactcc tcagtaataa gctcaatgga
    52501 ccaggagcta ttttttgttt ggctgttttt atcacttggt gcagggcagc tttttcacga
    52561 cctctccact aaacagtatt caaactgctg cttctcggta ataagcccaa ccaaacgaaa
    52621 aataggagga gctatttttg tttggctgtt cttatgactt gatgcaggac agctttttca
    52681 caacctctcc ttacatttta atggagccga tcactttacc agctgtcact gtacctaatt
    52741 gcttgatcac tacttcttct actttatcgt ttgtaaatac gatcatgatc gttggatctt
    52801 tttcttcgtt ttggatcaca tcaagatcca tctcagctaa tttcgttcct gttcctactt
    52861 cttggccttc tttgacagca atctcaaaag ctggctgatt catttggact gtatcgattc
    52921 ccatatggat caaaacttcg ataccatctt tcgtttccag cccaattgca tgtttgctag
    52981 ggaaaatact tgtcactttt ccagcgatcg gcgcaacaac ttctcttgat gttggaataa
    53041 cagcaaagcc gtcacccatc attttttgtg agaataccgg atcttttact tcagataaag
    53101 gaatcacttc tccagaagct gcggaaacta gttcttgttc tatacctaag tattgcttac
    53161 tacctgcttg tccatttcct gtagaaacca tttctggctc tggaatctct gctcctgatt
    53221 gcagcagatc ttcgatatct gatttcaaga catctgcttt tggtccataa actgcttgga
    53281 ctccattgtc tttgacgatc aatcccatcg cccctgctcg tttccaggct tcttcagtcc
    53341 ctactttttc tcgatcattt acacttacgc gtaaccgagt catacaagca tcgacatctt
    53401 tgatattttc ttttcctccc agcaaatgaa tgatctggac cacttgctga tctgctgttc
    53461 ctgttccgct gttagataca acggtttctt cactgtcatt gtcgtaattt ccgttacgtc
    53521 ccggtgtagc aaagttgaat tttttgatca agaaatttgc taagaaatac gtaacaacac
    53581 caaaagcgat cacacacaac acgaagttga taagatctcc acctagaccc gctttgatag
    53641 ctaacggtgt ccgagtcagc aattcgatat tcccaaatga atggacccgc aatggcaaga
    53701 tatctgccat cgcaaatgca gccccttgga tcactgaata aatgacatat aatggcacag
    53761 cagcaaacat aaacatgaac tccaatggtt ctgttacacc tgttagaaag acagccaacg
    53821 ctgctgaaaa atacattgat ttatatcttg ctttcttatc aggatcgaca ttacgataca
    53881 tcgcaaaagc cattcccatc aagatacctg aagaaccaat catttgtcct actttgaaac
    53941 gagccggcgt ccagttatgc aacacaaact catattgcga catatcccct gcacctttaa
    54001 gattcactaa atcagtggcc caagccaacc ataacggatc ttgcccaaat acttgtgtcc
    54061 ccgcctgtgc gcctgataaa atctcatacg atccgccaag ctgtgtatag ttgataggaa
    54121 tcgtcagcat atgatgcaat ccaaatggca atagtaaacg ttctaatgtt ccaaataaaa
    54181 acggtgctag aatcggtgcg ctttcttgtg attctgcaat ccataaacca aaattattga
    54241 ttccagcctg tacgtttggc cacaccacag caagaatcaa tgccacgatt gttgaccata
    54301 agataacaac aaacggaaca aagcgctttc cattgaaaaa tgacaaagca tccggcaatt
    54361 ttctataatt atagtactta ttataagcca ttgccccgac aaatccagcg atgatcccta
    54421 cgaatactcc catattcaaa gctggtgctt ccaatacact tgtaaaaaat cctttaacca
    54481 tgatcttcgt accgaacaga gtgtgggtaa atgcatcttc attcgcaagc atgtcacttg
    54541 tgacaccaaa gatagcccca gtgatccgat tgattaaaat aaatgagatc ccagctgcaa
    54601 atgctccgcc tgctctttct tttgcccaac ttcctcctat tgctaaagca aataaaatat
    54661 gaagattacc aataattgcc caaccaatat tttcaattac tccgcccgtt gtgacaagcg
    54721 gcgtccaatc aggattgatc aagggaattg atttccctat actgatcatc aacccagctg
    54781 ccggcataac tgctaccaca accattaaag cctttccaaa tttttgccaa aactcaaaac
    54841 taaatatctt tttcattccg tttagctcct ttacgcaatc ggtttcgtta aacgtattat
    54901 agcgtgcgtt ttcttttttg taaatgcttt attttttatt tttctgtcta taccattcta
    54961 taaaacctat aatacgtgtg ttcccttcta taattttctc ctaaaaattt atttttttaa
    55021 gcttttttct atgaaatatt ttcttttgtc tattgacttg tgcaatcggt tgcgtttatt
    55081 atgaacgtat aaaacagctc attaggagga gaaaaatgaa acagatcaaa cgactatttg
    55141 ctattgatcc atggaaaatc agcacgacac aattagataa aaaaaatctt cgactgcaag
    55201 aatctttaac aagtattgga aacggttata tggggatgcg cgggaacttt gaagaaactt
    55261 actcagggga ccaccatcaa ggtacttatt tggcgggtgt ctggtatccc gataagacac
    55321 gtgtcggctg gtggaaaaat ggttatccag aatactttgg aaaagtgatc aacgccttga
    55381 actttatcgc gatagatatt tcgatcaacg atcagctgat cgacttggct tctttggaac
    55441 cagaagactt ttactgggaa ttagatatga aaaatggtgt attatctcgt acattcacaa
    55501 tcactacttc tactaataaa gtacgcattt ccttcgaacg ttttctgagc attgtcaaaa
    55561 aagaatcagc ttatatctat ttaactatag aaatgcttga aggtagcgga acagtcaaac
    55621 tcgtatcaaa attggatgga aatgttcaaa acgaagacag caactatgat gaacattttt
    55681 ggaatgagat tgatcgtgga actatagaag aaatcggcta tttgacgact aaaactattc
    55741 caaacaactt tgggattgaa caatttactg ttactgcagc aatgcgccat ttcgttaatg
    55801 gaaaatcagt catccctgac tatcacgaag atactttagc attacatggt tgcttgtctg
    55861 cagaattatc tcaaggtgag acatggtcag tggaaaaaga aattatcgtt cttactagta
    55921 gagatattcc agaagcgcag caagcagaaa aagctgtctc agaattaacg aaccagacaa
    55981 acaattatat ccaagcaaaa gaagagcaaa cagcggcttg ggcagaacga tggaagcttg
    56041 ccgatgtggt catcgaagga gacgaagaag cacaacaagg tattcgattc aatttgttcc
    56101 aactattctc tacttactac ggcgaagatg aacgattgaa tatcggcccc aaaggattca
    56161 caggagaaaa atacggcgga gccacttact gggatacaga agcgtatgct gtccctcttt
    56221 atcttgcttt agccaaacct gaagtaacta agaatctgct gaaatatcgg cataatcaac
    56281 tgccgcaagc aatccacaac gctcagcaac aaggattaaa aggcgcgctt tatcctatgg
    56341 tcaccttcac tggtgtcgaa tgccataacg agtgggaaat cacattcgag gagattcacc
    56401 gaaatggcgc gattgcctat gcaatctaca attatacgaa ttacaccggc gatacggaat
    56461 atttgaaaaa tgaaggactg gaagttttag cagaaatcgc acgcttctgg gcagaccgtg
    56521 tccatttttc aaaacgagca aataaataca tgatccacgg tgtgaccggc ccaaacgaat
    56581 atgagaacaa tatcaataac aattggtata caaatacgat cgcagcttgg gtcttgcgtt
    56641 acacgcgaga aaattattta acttatcaaa aagaagctgc tatcactatc agcgaagaag
    56701 aactagccaa atggaaagat atcgcagaga acatgtactt cccagttgac gaagaattag
    56761 gaatctttgt ccagcatgac acattcttag ataaagatct catgcctgta tccgatattc
    56821 ccacaagcga tcttcctctg aatcagcatt ggtcttggga caaaatcctt agatcttgct
    56881 tcatcaagca ggcagatgta ctacagggga tttatttctt caatgatact tttacaaaag
    56941 aagaaaagca aaaaaacttt gatttctatg aaccaatgac tgtccatgag tcttcccttt
    57001 cgccaagtat ccattcgatt ttagcagcag aattaggaat ggaaagcaaa gctgtagaaa
    57061 tgtaccagcg aacagctcgc ttggatttgg ataattacaa taacgacaca gaagacggct
    57121 tgcacatcac ttccatgact ggtagctggt tgtcgattgt ccaaggattt gctcaaatga
    57181 aaactgccca tgatcagttg agattcgcac catttctgcc aaaaacttgg aaagcttatt
    57241 ctttccatat caattatcgc ggacgtttat tgttcatctc agtcacagat gaacaagtta
    57301 ctttcaagtt attagaaggt tctcctctag aaatttacgt ctatgaacag tcttattctt
    57361 tagcggatcg tctagaaata acgctaagaa aggaggaagc aaatgtttaa aggggtattg
    57421 tttgatttag acggtgtcat taccgatact gctgaattcc attatcgtgc ttggcgaaag
    57481 cttggtcagg aaatcggcat tacgatcgac cacacattca acgaacagct aaaaggcgtc
    57541 agccgagaag actcactctc tttgctttta gcttatggcg gaaaagaaca ctcttttaca
    57601 aaggaagaat ttgcagaatt agcgaaaaga aaaaacgatt attatttaga gatgatccag
    57661 acgatcgaac caaaagatgt cttccccggg gtcgtgcctt tactggattc tttaaaagaa
    57721 gaaaaaatca agattgctct tgcttctgca agtaaaaacg ggccattcct acttgaaaaa
    57781 atgggtctta caccttactt tgatgctatt gccgacccgg cagaagcaac aaacggaaaa
    57841 cctgcgccag atatcttcct ccttgcagca aaagctgtcg gactaaaagc agaagaatgt
    57901 atcgggatcg aagacgcgca agccggtatc caagccatcc tctcaagtgg cgctcaacca
    57961 attggcgtgg gacgtgctga agaccttgga gaggagatcc cgcttgtccc tgatacgact
    58021 tttcttacga tcgattactt gaaagaaaag tggcatgacc atggataatc cagagatctc
    58081 cgtcgtacca gttccagaga ctgaaataaa gaaaatcaca ttgaagaacg actacttaga
    58141 agtcgttctt ctcaattacg gtgcccgcct gcaccaaatc ttcgcaccag acaaagaagg
    58201 aaaatcagaa aatgttttat tgtcttacga tcgtttcgaa gatgttctaa cagacaaaag
    58261 cttttttgga gcaactgtcg gacctgtagc cggaaggatc cgggatgctt cttggggtga
    58321 gcatagattg gagaaaaact gcggatcaca ccatatccac ggtggcacga aaggctggtc
    58381 tttccaattt tgggaagtag aagttttcaa aactccatca tcaataggtg tggtctttta
    58441 cttaaaagat gaattttcta cctatccagg accaatcact gctacgatca cttaccgttt
    58501 aacaaaaaac gaattagaga tgacaacctc tgctagtagc cttgttgaaa ccatctgcaa
    58561 tccgaccaac catgcctact tcaacctttc aggaaatgga acaagagaca tctatgaaca
    58621 tcagttaacg gtctttttag atggtgtgct tgaattagat caagaaaaac tgcctactgg
    58681 aaattggaca aaaaaagaaa aactgccaat cgactttaga aaatccccaa cactgcaaga
    58741 gatccttgca tgttatccag atggactaga tgatgtattt cttttgcatc atcctaggct
    58801 ttccaaaact tccttacaat tattcgagaa gcattctggt cgccaaatga ctatagcaac
    58861 ttctaataaa agtatggtat tattttctac gactggattc gaagctgatt tctctgtcaa
    58921 tggaaaacag atgcattcaa actacggatt agcaatcgaa ccgcaagaaa tccctgatat
    58981 cgttcatttc cccaaatttg gatcgatcaa cctccatcct ggtcaagaac ggatcagtca
    59041 gacgatttat cggttctctg cacaataaca agagaaaggt gtttttatca tggctattac
    59101 cgtaaaagat gtggcgaaaa aagccggtgt tgccacctcg accgtctctc gtgtcatcaa
    59161 cgatcatcct agtatttccg agacaacaaa gaagaaagtc cgaaaaatta tggatgaact
    59221 aggttatgtt cctaacatga ctgcccgcaa tctaggaaaa cgcatttcca gtgccatcgg
    59281 cgtaatctta ccccctcttg attcaaaaga gcggatcggt aacccatttt atcttgagat
    59341 catggaagca atcaacgaag aagcgcggaa ttatgatatg actacagcaa tcgctactgc
    59401 taaaaatttt gaattgctgt tagagaacgt ccagcgtatg catttacaaa aacaagtaga
    59461 tggttttatt ctagtgtatt cagatagtca agatactgtc attgattatt tataccaaaa
    59521 ccacatccct ttcactttga tcggacagcc ttatcatcat gagaacgaaa tcgtttatgt
    59581 agataatgat aaccagcttc taggtaaaca agcaacagaa tttttgatcc agaatggaca
    59641 taagaatatc ctgtttgtga caaacacgac tcatgaaagt ttgtatttcg aacgatattt
    59701 cggttatcaa aaagcaatga tgatggctgg tcttcctgcg ttatccagtg tagtactaga
    59761 gcatccggag gattatctgt cctttgagaa aacgttgaaa gaaaacgaag ccacagcatt
    59821 ggtggtcatt gacgatatct tcgcccttcg cacgatgcag ttggcgcaaa tgtatggcta
    59881 tgtcattcca gagacactct ccgtcattag cttcaacaac tcgatcttct caacattaac
    59941 acacccttac cttacaagta tcgatatcga tatctccgaa ttaggacgtg tcgctatgca
    60001 aaagctgcgc gaattgatcc atgaagaatt gagcagtggc gtacgtttgg tcatccctca
    60061 tcgcttgatc aaaagagaga cagtcgttcc tttagaaaac ccatactaaa tagctgactc
    60121 actaaatacg ctgaccattt atcctatggt cagcttttta tgtaaaagaa gatactactt
    60181 ctaacacatt gtttatctgt aaaaaagagc gtgggacaaa agtaaagaac acttttgtct
    60241 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
    60301 attcacaaaa atttaaaaag caattttctt gagtttcttc ttatttcttg gagttaaacg
    60361 cttctgtccc agcctctttt ttccttcctt caatttttta cacgtcgacg attcaataaa
    60421 aaaccgccta atattgtaaa gacaggtgca agaatcgaga aaaaggcgaa tggcaagtaa
    60481 tgcaacgcgc taactttcat cgttcccata atgaatgtgc cgctgactcc ccacggtacg
    60541 agagaattga cggtcgcacc tgaatccgct agtgttcgtg tcaaataggt ttttgataag
    60601 ccaacgtcat caaaagaacg cttgaatgtt tctcctggaa gaatgatgga cagatactgt
    60661 tctccaacga tcagattgat tccgatacag ctcaaggcag taaacccgac taaacgagaa
    60721 ggtcggtcca tcttttcttt taattcttga acgatggtat caacgatcag atatttgatc
    60781 agtaacccac ctaatgccaa tgcaagtaaa atcaaactag cagaacctaa catactcatg
    60841 atcccgcctc gagaaagcag ttcatctagc tttggatcag gtgtatttgc gacataacca
    60901 ttcatcaaga tgtctgctgc ttttccgacc gtcaaacttt tctcatggat aaaagaaaga
    60961 acgagagcag ctgtcgatcc cgctagtaat gtagggatag ccggaatttt tttgattgcc
    61021 ccccccaaat aaaataacta gtggaatcaa tgtccaagga gagatccaaa agctcgcttt
    61081 catgttttgg atcatttcat tgatactagc tagatcggct gaatgactgt tatgtcctaa
    61141 tatcgtataa aaaatcaacg aaaggacgaa tgctgggaaa tccgtataac gcataccagc
    61201 gatatgttcg aatagattaa ctcctccaat acccgctgcc aagttggtcg tatctgataa
    61261 aggcgagcag ttattcccta aaaaggcacc ggaaacgact gcgcctgtag tcattgcatc
    61321 attgaatcca agtaaatgac cgatccccaa aaaagcaatt ccaatcgtcg aaatcgttgt
    61381 aaatgaactg ccgacagtca ctccgacaat tgcacaaaca agaaatgctg tcggtaaaaa
    61441 gaaacgcaca gaaacaagtt taaatccata aaccataatc gtagggatgg ttccagataa
    61501 aatccatgaa gcaactaaga caccaatcaa aagaaaaatc aggattggaa tgatccctgg
    61561 agtgattcct ttgatgatcc cgtcatggat ctcatcccat gtgaactttt taaatctgcc
    61621 ataaaacaac aaacacatga aagctgcaag gatcgggata tgtggcgaga gctggaatcc
    61681 gatgatcagt actcctagga gtgccaacaa cacgatcaat acagcgatac tttcttttaa
    61741 agaaatattt ttattcatcg tcgatctcct atttcaaatg aaaaggccct gccatgaaaa
    61801 aactattcac ttggcaggac ctcctactaa atcagcgaca aaacgtcggc tgaaagactt
    61861 atttttttat ttttcttcta aacttttttc tacctcaatc ccccaagaat ctttcttgaa
    61921 gtgattgatg atcaatggaa taacgaacat gaccactgtg atagctgcta ctaataatgc
    61981 atcactcaat gtcgctgtac ctaatgtagc aaatacgaca acgatgatag agaagatcag
    62041 catgcagctg actacccaag ctaatccgtt tccgttttta ccaattcggt aaggacgttc
    62101 gaattctgga tgtttcttac gcattttaag caatgaaaca gcaatcaaaa tgtacacgat
    62161 acaataaata acagttgtag catttgtaag tgtcaagaat acagcactta cgtcatccat
    62221 tacaccataa agcaaagcaa ataatgaaat aacgattgat tgtgttagaa cgacatttct
    62281 agatacgccg tatttgtttt ctttatggaa tccgaatttt ggtggaagga atccttcacg
    62341 agctacttgg atgattgttt ttgatggtcc agtaacccaa gctgataatt gtaaaagcac
    62401 accaataaat accatgaagc tgaagatatt tccgatcact tctggtaagc ctaggatttg
    62461 acagtcaatc aagataggct gcgtgatatt tgctaattcc atttttccat ctggtacgac
    62521 atttgctaca agcatcgcat tgatgacatt caataaaact aatccgatca aagcgataaa
    62581 tacgcctttt gtataatttt ttgttgcgtc tttcaaacga ggcatgtaaa cagaactcat
    62641 ttcgatccca acaaaaataa atgtgatacc agctaagtat ttcaatgaat caatatgttc
    62701 caagtcaggg aaagcttttg accatgaaaa gtcacctaga tagccgtttg agactagtcc
    62761 gactttgaag gctgccaaaa cacctaaaac gaacatgatg actactggga tatatacccc
    62821 tagccataca ccgatgttcc cgccgacttt tgccatatcg aatttcaagt tcaagatcgt
    62881 gatgatccag tagataacta aaatacaacc taaaacgaac cagtgattat tgccaagttc
    62941 tacattacca aatgtgtttc ctaacaatgg tcctaaagta gaagcgacca ttaccatacc
    63001 tgggaacatt tgcacccata atagccatgc aacgacaaat ccccatttgc tgcccagtgc
    63061 tgtttttacc cataactgag gaccgccttc ttgaggaagc atcgtggaaa gctcaccgga
    63121 aaccattgat atcggaccgg caaaaaacaa aactgcaaaa attgaataaa aaatcaatgt
    63181 ccaaccgact gcggctaacg taggaatact ccgaaccgtt gcacacagtg ccattgtcag
    63241 accgataaag gtcccaagac ccattttact tacttcagat ttactcaccg ttgacactct
    63301 ccttgatttt ttggataaaa taacggtgtc tttgaagtag tttcagcaat aaacgaaaca
    63361 attcagcgaa tatttgaggg gattctttga gtttattgct tgaagggttt cttcaaagac
    63421 aacctcaaaa caaagggatc gaagagctta ggtctcccct tgctcttcag atccaaacat
    63481 gcgtcagaaa cagttagtat tcaagctgtt ttctaacatg attaccttgc ttattttgct
    63541 tcgcttgcca ataattggtc tgcgtagatt ttttccaatt tttcttgaag agctgctttg
    63601 attttttcag catattcttc aaagtgttct tctttgttca tgtatggtgt cattacgctg
    63661 gcacgcaata cagttacttt tccggcacgg ttccattctt catctgagaa tcctagttgg
    63721 ttcacaaatt gtaatgggct gttgccatag tctgggatag caaagtcagt atgtgaagtt
    63781 aagaactcat taccgtaaat gcttcctttc acgtatgaag aataatcata tacgtcatgg
    63841 ttcaatttat tcattgcaac taagtcatcg ttgccttttt ctttgaatac atagtctacc
    63901 atattgaaat ctggataagt taatggatga acttcgattt ctttgtctcc tactttaaat
    63961 gacaagtcat tcaagaagtt gtagaaacga tgtgcacctt cgattgatgc acccattaat
    64021 ttaccatatc ctgtgacatt caaaggtaag acatggtgtg ctgcccaaac gctggctgct
    64081 gttgcccctg cttttgaacc ttccaagata taagccccaa gtaatgctgg gatatctgcg
    64141 cctttttcaa atacatatgt cgcaaagtaa gagataacgt ctctcatgcg gatatctttg
    64201 atgacgatac caccggcaga atatggaaca tagcccattt tatgtgggtc aatcgttaca
    64261 gattctgctt cttcgattgc tttatatgca ctgtgtactt cttctaagat ataatctttg
    64321 ttttctgtaa agacattgta tttgtaatga acatctttta aatcttcaaa tggaatgaag
    64381 ttgttgtctt cgtctaagaa aatcgcacgg ccgtatccgc cataagcagc atctacgtgt
    64441 aagtagaagt aaataccgtc tttttctaat acgcgacgca atgcaacgat tttatcgata
    64501 ccgtcgattg ctccttcttc tgttgatcct acaacaccga ctacacctag gattggtgtt
    64561 ttttcagctg ctagaccacg aacgattttt tcaagttcgt tgatgtccat gcgatagttg
    64621 tggtcaactg gcactggaat cacttggtct aaaccgatac cgatgatgtc ggcagctttt
    64681 agccatgaat agtgtttagt ttgtggaacc aaccattttc ctaatttttc taaatgtttt
    64741 ccgctacgtg ctgagtgagc tttgatttcg tcgatttttt ctgggacgct gtctaacaga
    64801 ttcatgattt cttctgttga caagttcatt aattcccaat cgctttttcc agcaactagt
    64861 tcaggtgtca cttctttcat tgcaagcggc aatgatttga tgttgcgggc ataccaaagt
    64921 ccttctaagt ttgctaaaga accatcagca acgatgtggc cccagccatc tttatagctc
    64981 attaattttg caaattccat tcctacttct tcttccattt ggcttgttgc aggagaagat
    65041 tcataggcaa cgttattacc attccatagc atagcaaaat tgtacgctag taaagatggc
    65101 atcaatgttt cagagttcat atgaccccag taacgtccgg cattatgcca aggaacggaa
    65161 tgggtacgca tccgcgctga aatttctgat agaacatcct ttgttttatt cacagtgtgt
    65221 tcaaaactag cactgctttt ttcttctggc gtaataatag gcatgtcttg aggcatgtag
    65281 ttttgacgcc agcctaaatg ttcatccacc aattcattca acaaagcttt atagatttgg
    65341 ccgttctcag ctttgtcccc aatgaatagg gcatttaggt ttagatcttt cgacaatgat
    65401 tcactcatag tgaaaccctc ctaaaaaaat atttaaattt tgtcgagccc tacattacac
    65461 ctgttcttct attctgtaaa ctaagttttg gcctgatttt taatcatatt ttaatatgta
    65521 tcaattatcc gaattgttca cacttttgaa ataattaaaa aaaacgaggg aatttacaaa
    65581 tgtaaactcc ctcgcaaaga ttgtattaac gacaaccagc gttctatttt aggatgggtt
    65641 tcaaaattgg aatgttgtaa tagtatttcc ctttttcaag gtaaaaactt actaaattct
    65701 aatcaattac tttggccaaa aagtaatttt tcttaccttt tcgaataacc acaaacttac
    65761 catcgaattc atcggatgga tttatgacaa aatttaaatc ggtaacgcgg tcaccgttaa
    65821 tacttatagc tccgtttgaa acatcttcac gtgcttgacg tttagatggt tcaatttttg
    65881 tggaaacaag cagttccacg atattttcag gtgtgcttga aatttcaacg ttcggcattt
    65941 taccgaatcc ttgcgcgatt tcttccgcat ttagttcttt aatatttcca gagaacaatg
    66001 cttgcgttat tttttgcgct tctttcaagt cttcttcact atgcacaaat cttgtaactt
    66061 cttctgccaa acggcgttgt gcttcacgtt tctcaggttc tgtctctact tttttcgcta
    66121 agtcttcgat ttcttcttga gacaagaaag taaagaattt caagtatttc actacatcgc
    66181 gatcatcttg attcaaccag aattggtaga actcaaatgg tgaagttttc ttcggatcaa
    66241 gccaaacggc accgcctgca gtttttccga atttcgttcc gtcagccttc agcatcaatg
    66301 ggatcgttaa accgaacgct tctgcttctg gtccttctaa ttttcggatt aggtctaatc
    66361 cagctgtgat atttccccat tggtctgctc caccgatttg caattgcaca tcgtatgttt
    66421 tatgcagatg caaaaagtcg atagattgca ggatttggta agtaaactct gtaaatgaga
    66481 ttcctacttc caaacggctg gcaacgatat cttttgctaa catcgtgttg atgttgaagt
    66541 ttttaccgta gtctctcaaa aattcaagta aagagatttt tgacaaccag tcgtagttgt
    66601 tcacaaatgt gatatttgca tctttaccaa acaattttct catttgattg gaaagtgcgt
    66661 ccacgttatg ttgcacttgt tccatcgttt gcaacacacg ttctgttttg cggccgcttg
    66721 ggtcgccgat cgttcctgtt ccgccgccaa tcagaatata tggatgatgg cctgccaatt
    66781 ggaatctttt catcatcata aatggaatca aatgtccgat atgcatcgaa tcaccagttg
    66841 gatcaacgcc gcaataaagt gaaatgctct tttcttcaac gagctcgcga agtctttctt
    66901 cgtttgtttg ctgattaatg gcgtcgcgcc aagttaattc atcaataata ttcattttac
    66961 tgacctccgt gtagtttttt tatgaaagca ggaacctgct agcatgtgta attaattatt
    67021 tcttcaggat aggataggaa ataaaaaaag tcccttggca tataagccaa gggacgaaat
    67081 ctcgcggtac cacccaattt gtatgtctag atatccaaca tacctctcga acatttaacg
    67141 ctgtcgcgtg gcaatcactg ccaaagactc ctgaaatgta attcgcttta aagcatgtac
    67201 tggtttgcag cgaccaccag ctttctgaaa cattggcttt aacaactact tcgtttcgat
    67261 cttcgtcttg ttattattaa tatgtgtcta tcatagagcg caactttttc tttgtcaaca
    67321 gaaaaaggat atttttttta aattcctcat tttttctttt ttgaatccgc tctaattccg
    67381 aacattttat tttcaattat tgttaaaaga aataactttt tctgtatttt ttctgcaatt
    67441 tatcgagaag tcactttact ttgcctctta ttctttcttc gttacaataa ggaatgggac
    67501 aagtaaaaaa atgaaaaagc aagggacgag gtatatggaa aaaaagcaaa aaattatttt
    67561 aggagccact tctgctttaa ctatcgttat tttaattcta agtttgtttt ttgtcatccg
    67621 atcatctaca aaaaaagaac caatcattcc tgaaaaaaaa ataacagaaa aagcaaaaga
    67681 accgacagat gataagcaac aactagttac tcaagcaaaa aatctggctc aaagctacga
    67741 ttatgaccaa gcgattgcgt tattggaaaa agatagtaag aacggatcta ctgaaacaca
    67801 acagcttctt caaacactaa aaaaggagaa agaacaactg atcgactggt ctgatcctac
    67861 tcagatctct catgtctttt tccacagctt gatcgtggac ccgcaaaaag ccttccactc
    67921 tcaacaggca caaggataca aagattatat ggtgactgtt gaagaattca accgttcgat
    67981 cgaacaactt tatcaaaatg attttgtttt agttaatttg aatgatttga tccaaaaaga
    68041 cgaacaagga aatctttcct ttaacgggct tgcgctacct gaaggaaaaa aaccattggt
    68101 tctttcacaa gatgatgtca gctattatga atatatggat aattccggtt ttcctagccg
    68161 attggtcgta tcaaataaca atgaaatcaa aaatgtctat aaagagaaag ataaagaaga
    68221 aatcggtgac tttgacatgg ttcctctgat cgatgccttt gtcaagaaac atcctgattt
    68281 ttcttatcga ggcgcaaaag gtaccttggc cctgacaggt tacaacggag ttttaggtta
    68341 tcgaacatca aaatctcaat atggagacaa tgaaaaaaca aaaaaagaga ttaaagaagc
    68401 taaaaaagtg gcggaacagt tgaagaaaga cggctggagc tttgcttccc atacatgggg
    68461 tcacttgaat atgactcaag cttcactaga agatgtaaaa aaagacaatg aattgtggca
    68521 gcaagaagtt gcacctatcc taggaaaaac aaatattctg atttatccat ttggtgcaga
    68581 catcagcgac tggcagcctt attcagcaga aaatcaaaaa tttgcttact tgaagagtca
    68641 aggtttcgat attttctgta atgtcgatgc ttctacacca gcttggggac aattaggtac
    68701 ggatttctat cgaaatgctc ggatcaatat cgatggcatt cgttttcaat ctgatttaga
    68761 cggaaaaaat cctattcttg atccattcat caatgtccat gatgtctatg acaaagaagc
    68821 acgcgaatct gcttgatttt acgtcattta tgaaccaaaa aagccgaact gacattttat
    68881 cgtcagtttc ggctttttta tgctttattt cttcttcggt gcgattccct tgatcaggac
    68941 ttctgtccat tctgctgtat atggaagcag ttttgcgtat atctccggct tagaaattcc
    69001 ttctaccatt gcttgaaaat agaggatcaa gaactcatcc gaatatttca aatccacttt
    69061 tccttctttc cgccctcgat ggaaaagatc aagcatgata ctgaaacttt cttgcgtata
    69121 cgcatccatc gcgtcagaaa attctttttt ttcttttttt gtatagtatg tcatcaaatc
    69181 gatataaaat tgtttgttca ctcgattgag ataacggatt ttgttttcac tcatggcaat
    69241 cagtgtttct tcaaatggaa gattttccgc aatcaacgct ttcgcttctt gccctaaatc
    69301 attcataaat gcaaaaaata cttcataaat cagcccttcc ttgctgccaa aatatttaaa
    69361 aatcgtcgct ttacttacct gagcgttctc agctacctta tccattgtca ctccagcggt
    69421 tcctatgtct gtgttcatca agtcaaaagc tgcttgtaaa atctctttct ttttctcttg
    69481 tgctctcttt tcaaaaccgt tcatttgtag agcctcccgt aattttaaac ttttataata
    69541 tatatagttc aaatttattc tgaggtttat tataactatc tattgagaaa gtatcaagct
    69601 agcaattcct tgtttatgaa ttcattgaca gaaatttata aaaagaatat tatgtactaa
    69661 aataataaaa aaagttttat aaaaaggtat aaaacctttt tattaaacta tttaatcttg
    69721 tttagtatat atttttagaa aaaggagtgg ggtttttatg gcagaaatcg tcaaagtcac
    69781 acatttgaaa aagagctttg gtcgtttcga agctttaaaa gatgtctctt tcaccgtaca
    69841 ttcaggtgaa gtcgttggat ttatcggacc aaatggttct ggaaaatcca cgacgattcg
    69901 gacactttta gggattataa aaaaagacgg cggaacggca acgatttttg ggcaagatgt
    69961 atgggaagat agtttatcta tccatgaacg tctttcttat gttccaggcg atatctcttt
    70021 gtggggaaat ttgactggag gagcgatcat cgatctcttc atgaagcttc atggaaaagg
    70081 gagtgctcaa aaaaaagatg aactgattca acgtttctct cttgatccta agaaaaaagc
    70141 aaaaaactat tcaaaaggaa atcgccaaaa agtgggcttg attgctgctt tggctgttga
    70201 ttcggatctc tatttatttg atgagcctac ttctggttta gatcctttga tggaaacgat
    70261 tttccaagaa gaagttgaaa aattgaaaga acagggcaaa tccatcctac tttcttctca
    70321 tattctcagt gaagtcgagc gactagcgga taaagttgtg atcatacgcg aaggaacact
    70381 cgatgaagaa ggaacactcg atgaattgcg tcatttgact cgttcgacca tcactataga
    70441 aacagaagca gagaatagtc acttagcaca attgaacggt gtccatgact ttgtgcaaaa
    70501 aggtcacctc gctcaatttg ctgctgataa cgaagctttc gatgtgattt tagctgaagc
    70561 gtccaaatta ggtgtgaaaa aatttgaatc tattccaccg actcttgagg atttattcat
    70621 gagacattat gaaggatgag gaggaagcga aatgactgat aaattttcac gctggtccac
    70681 ccttttttct caaaacctta gccgtgactg gaaaaagatc ctgatatggc tagtcggtgt
    70741 cactgctttt tctggtggtt ttgtccctgc gtttgaagaa ttgacttccg gacaaggatt
    70801 agctggatta tacgaaacct tgcaaaaccc ggcaatgatt gcaatggtcg gaccaactcc
    70861 agcttcgaat gctgctgagt atactttagg agcgatgtat gcaaatgaaa tgttgctttt
    70921 ttgcagtttg tttgctgctg tgatctctgt tttacacgtg gtgagccaaa cgagaaaaaa
    70981 agaagaactt ggtctgattg aacttattcg ttcctttcga gtcggacgtc aagcaaactc
    71041 tttagctgtc atcgctgaaa gtattctgat caatttgctt ttagcaatat cgatcagttg
    71101 tacgatgatt tttttccaag cggattcgat cactgcagaa ggtgcttggc tttttgggct
    71161 atctgtaggt agtatgggga ttttggggag tgccgttgca ctgtttgctg cacaactgat
    71221 gccaagttca gccagttcga atggtctgtc tttagcgttt ttaggtggac tttaccttct
    71281 acgagcaata acagatgtag ctgattcctc cctttcgatg tggaatcctt taggctggtc
    71341 ttatttgacc tatccattta caactaacaa ctggattcct ttgctttatt tgtttttgtt
    71401 cagtctaatc ttgataatca gttcatttgt tttagaggaa catcgagatt tgaacaccgg
    71461 ctatatcccc gaacgtgaag gaaaaccgta tgctaaacgt tctcttttat ccttgcgtgg
    71521 tttattattc tatctaaata aagggatgac aatcagttgg cttatcactt ttggtttgat
    71581 gggggcggca tacggctcta tctacgggaa tatgcaacag tttttagaaa gtaacgactt
    71641 aatgaaacag atgtttatcc aatctggcgt ctcaattgaa aaaaacttta caagcacgat
    71701 catggtcgtc ttgatttgtc tagctgctat tttaccaatt gctagcatca atcgtttatt
    71761 tacagaagaa acccacggac gtatgaatca gctgttcgca acaaaaattt ctaggaacca
    71821 actttattgg accaatatgt tactagctat tctatttgct atattggcaa tcctgattag
    71881 ttctggtgca ctagggcttt ctgctttggc ttcgatgaag gatgcgaaag acatggatct
    71941 attgatgttt cttaaagccg ggttcaattt cctgcctgcc gttttagtgt ttatcggaat
    72001 tagtggcttt ctattcggat ggcttcctcg aatcggtaaa cttgcttata tctacttagc
    72061 ttactccttt gcactcaatt actttggcgg aattttggat ttaccagaat ggttttccaa
    72121 aacagctgtc cctagctggg ttccacggat gccaaacgat tcttttgatc tttccgtgtt
    72181 ccttacgtta tcatgtatca gccttgcact gttcgtcctt ggttctattg gttataggcg
    72241 aagagactta ctagaaggat aataaaaaag catgtacaat ttcatgctag cctccaaatc
    72301 tgggtcaaaa atccaacatt tggaggtcat ttttttattt acaagtcttc taactgctct
    72361 ttatcaatga tccagacttc tcgattcttt ctttttacat aaccattctc ctctaataat
    72421 ttaaattttc tagataaagt ttcgggggtc gtaccgataa atgcagcaag ttctttcatt
    72481 ttcattggca ggaaaaagtg atccttccct gtcgctttag ctaagtcaag cagatagaca
    72541 gcgactcgtt cttctacttt ttccatcatc aaaaaagttg tctgctgctg tacttttgtt
    72601 aatttctcaa cgttgattgc taaaagtttc agactaaggg cgggataatg cagtaagagt
    72661 tccgagaaat ctttttgtct caatatgcaa atttccgttt tttctagtgc ttcgccaaat
    72721 aaagactcat ttggaacgcc tagcaactgg ctctctccct catatccgcc cggctctatt
    72781 actcgtaaaa gctgttcctt tccgctagca gataattgat acactttcat actgccggag
    72841 gccacgatca ctaattgagg ttctccattc ggcgcaagaa tctgttctcc tttttccaca
    72901 tagtgatgtt tgacaagtgc gtgtactttt tcttgatctt gctgtactaa gtgattgaac
    72961 aaaggaacaa atgaaacaca taaatgatca tgactcataa tctctcctcc ttctaaacag
    73021 ctatttctaa taaagaaaca taacttccct tattccaact gataattttc ttttatcata
    73081 gcataaacgt caagcgaacc agataccagc aaatagagtg gatttctttt tgtcccttgc
    73141 tttattttcc ttcttttgag accttaagta attgattcct atcaattttt taaatattta
    73201 ctttttgaat aatcaaaaac aaaccttcac tcgcaagccg agagtaaggt ttgtttttcg
    73261 cattgcttat ttcgtgttgt ctattgaaat ttttccgcac ctagcttttg atatagtggt
    73321 gctagttctt gtaaggtttc agcggttatt tgctcaacgt gttcgatttc ttgcggatag
    73381 aagaatagtt tacccatttg aaaggttcgg tctctcatcg cttttttcaa ctcttcttgt
    73441 ttctttgtat cggacaaata gtcagacaaa gctaagtggt cgtcaagttc atgttctggt
    73501 tgcggccata tgtaataatc cttgatatcg actgttttgc tccactcttt cagtatcgca
    73561 agcaactggt tatacgctgc aatgctacca tatcgttctt cgcttttata atgttggtac
    73621 atcaaataga tttggtattg tttttgattc aacaaaactg ctagacaggc attctcgtct
    73681 tgacgagatt cgcttcggta cgcgctccaa aaatgactgc gtaaattcca gccattcgtc
    73741 cagctttcga ttttaggttt gctcatgccg tacatatcag gcaaaagtgc agctgtctgg
    73801 agctgaatct ctttccattt ttgccagtgt tctttatatt ctttcttgat ttgttcaatc
    73861 ttatctgttg gatggctctc tttgagctgt ttgaatgcgt agattggtcg atcaaacaac
    73921 tgataatctg attttccaag ttccattgtt tcgcctcttt ccgttatctt ttgtattcta
    73981 cctgaatttt gcgatatgga caaatagagg ttgtgaaaaa gctgttctgc atcaagtcat
    74041 aagaacagcc aaacaaaaaa ctgcgatgag catcaccgca gttttattga acttaaggtt
    74101 gattgatcac atctaaaagc gttgaaaata aaatggcact agaagcagct cctgggtcga
    74161 tatgtccgat tgcacgctct cctagatagg aagctcgtcc ttttttagct accaagactt
    74221 tggtgtgttc ttttgcctgg tcaatgattt cttttgttaa attccctgcc ttcaatgcct
    74281 ctgtgactgg cagccaaaca tctaacatcg ttttatcgtc agcttctgcc tttcctcggc
    74341 tttgaatacc cgctgttccc tgctcgatca cttcgcctaa tttttcttga gaatcaatag
    74401 aatcgacctc ttttgtcgct ttcatcatgt tcatgaatgc agatccgtat aacggaccag
    74461 aagccccacc gactttcgat atcatcgcca tagagaatac tttgaatgta tcgctgattg
    74521 tttcaggatg atcggcttga aaagcttctt cataagctga aacccctctt cccatgttat
    74581 ttccatggtc tccatcgcca atcggggtat ctagatcact gagatattgt ttgttctgat
    74641 tgattgcctc tgcaaattgc gtgagccatt cttggatttc ttgaacggtt agtttcatat
    74701 tatcaccctt ttatcttgag attttttacc atgaaatcgt ctgtacattg ctttctaaag
    74761 aatctttcca ttgtgtctcc gtcaagtcga tcagtgttag agaaagacct tgcatatcta
    74821 gtgaggtcat aaaattaccg acttttcgga aaactacatt gacgcctctt tcttccaaca
    74881 gagctaaaac atcattcatg aacacgaact gttccatcaa aggcgtcccg cccattccgt
    74941 tgactagtac acctgcttct tttggtaaat tcgagtaatc atctaaaatc ttagtaacaa
    75001 gttcctttgc cagtacttta gaaggctgca tcttttctcg acgatagcct ggctcaccgt
    75061 ggataccaac accatactcg atctcatctt ctcctagttc gaatcctggt ttccctactt
    75121 ctggtacagt tgctgctcga agcgctagac cgatcgtctt agttgcctgt acgacctttt
    75181 ctcccagttc tttcaactca gctagggaag caccgtttct tgctgcatcg cccacgattt
    75241 tgtgtacaag gacagtacct gcaactccgc gttttccagc agtatacgta ctattttcaa
    75301 cggcgatatc atcatctacg atcacacttt ctacttcaat atcgtccata gcagctaatt
    75361 cctttgccat atcgaagttc aatgcatccc ctgtataatt cttaacgatc agcaaaactc
    75421 cttttccact atcggcttcc ttaatagccg tctgaatctg atctggagtt ggagaagtaa
    75481 acacatcacc aagcaccgct gcacttaaca tcccttcccc tacaaacccg gcatgggatg
    75541 gttcatgtcc gcttcctcca ccagaaacca aaccaacttg ttccgctttc tgattcttgg
    75601 ctacaacacg ggaagattct acacgatgaa caagttctgg atagcttttt actaatcctt
    75661 ccagcatttc ttcgacaata ttgcttggat cattcatgat ttttttcaat ttattcccat
    75721 cctttctttc cggcattttg tgcttctgtt aagatttgct gagtatcatc tgttataccg
    75781 gcagtgatgg ctgctgcaaa agctccttcc actaaaggcg catccaccag atgataacgt
    75841 tgctgctgct cttcttccaa catgtctttt gccagttccg agttcaatac cgcgctaccg
    75901 atatccgcaa aaacaaaata actagctgca tcgcttgatt cattgactgc ttctacgatt
    75961 ttcatcgggt ctgatccgat ctcgccattt attccgccga gagaaaaaat ttgcacctct
    76021 tcggattttt gcatctgctc aatcatttct ttaataccat ctgttacttt ttgactatga
    76081 gaaataagca aaatactttt tttcacaaga atcttccttt cttttacata gttgctaacg
    76141 attggtttcg ctttcattaa tgaacaattc aagtatataa taaatttcta attttgggaa
    76201 aatatgtgta gtgcttcttg aagtttgtta tactttaatt aaaagagagg agtgatcgaa
    76261 tgattacaac aacaacgaac agtgtagagg gaaaagccgt agtagcttat aaagggatcg
    76321 tttttggtga ggtcattact gggatccatg catttaaaga cttggaggcg gggttgcgaa
    76381 atatctttgg cggccgctca aaaagctatg aaaacgaact aatgggtgca agagaagaag
    76441 cacttgccga aatggccgaa cgtgcaaaag cattaggagc tgatgcgatc attggcgtaa
    76501 aaatggacta tgaagtatta ggcagcgaca atggcatgct gatggtcaca tgtagtggaa
    76561 cagctgtctc cacgagataa gtaggggaca tctgttttaa taactaaaga gagatgggac
    76621 atgtagtggc actcaagaat tagatttttc agtctaactt cgaggtactc taccttccca
    76681 tcctctcttt tttatttctt tttgcggatg attccgtaag ctgctgcgac taacacaccc
    76741 gcccctgcta aggaataact gacagaagct gttttttcat ttgtttttgg caaagtctga
    76801 cttgttgatt tggatggctc tgtcgtttgc tgaactgttt ctgtcgtgct tccagaggtc
    76861 actgattttt ctcctgccga atgcaaaata tcttttattc gttggaaact agctgctaag
    76921 tcagcttttt ttgcttcaaa atcattagca actgtttgtg cttcgctgat ctttccgtgg
    76981 attgcttgac tggccgctgt gatatccgct tgagtttgac ttagctttcc agaagctgtt
    77041 tgagcaacct gatttaattg ctgattgaat tcttttgctt gttggatctt cccgtcaaga
    77101 tctgtttgga cagcttccgc ttttgctttc gcttcggcaa gctttttctc aagttgtgca
    77161 cggtcatttc ccactttatt tttaagatca gctaaatctt gatcgattgc tgcttggtct
    77221 tctttcaatt tgttttttgc agcttctaat gcttcttcga gttcttttct tttattttcc
    77281 aagtcttgca aatgatcgat ttggtcagaa gaggtagaac tatttattga tgtatcttct
    77341 gaagatgaaa tcgtttctcc tgaattatct gtcggtacat tggaagtcat ttctgtttcc
    77401 gaggcaccgt tttcagcacc agaagagctt atggttgttg aaggttctgt ttgagcaggt
    77461 tcagaagttt ccgcaaaagc tgtctgtccc aataagaaaa tactggaaac agcaattggc
    77521 cagattaacg gcttcattct ttttttcatc acttttccca tccttactac tttttaacta
    77581 atttcttatt ataagcaaaa atgtttggaa gaaccataaa cacaacaggc tgtttgtcta
    77641 aaaaacggtg catcttttat ttttttgtac gttccgggct tttccatgtc ccgcttccat
    77701 aacctaaaat cgttttgact gctggaatga aagtcgtcac gatcgttatc gcgttcacta
    77761 tccagaacaa aagcatatat agtggtgcga aaagaaggta tttcaatttt cttcgtcgat
    77821 catctacaat cagcgaagct agcaactgga aaaatcctgc gaccatttca aagcagatga
    77881 acacaaaact gaatgtaaaa gtaatataaa tctgttcgta gtttccttga tatacataat
    77941 gcccgattaa tccagcaaaa agaactacgg aaatacaaaa gaatattgac cagacaatac
    78001 tcaatgtttg atcaatgaag atgatcgttc ttccaatatg tttaaaagga tggagcatca
    78061 cttttttgaa attcgtcagc cagacttctg ttccaccttt tgcccaacgt tttctgtgtc
    78121 gatatagcat cttcaacgtc acaggtactt ccatgaaaaa gataatctca ggagcaaaaa
    78181 cagataacca gtcatttaac tgatgatccc aagcaatact gatgtcttct gtcgctcgat
    78241 cttgtctgaa tccgcccaca tcgatcaagg cttcttttcg atacatcgta tttgctccac
    78301 tgtacgcata aagaccaccg aaaacagctg actgtgttcg tttaatgatg cccacgatac
    78361 ttgagaattc aaccgtttga gattttgcaa tcaatttggt acgattttgg acatccatat
    78421 ttgcagtgac cgcagcaata tgtcttgcac cagggcgaat gaaataattc acatacctaa
    78481 tcagtgcatc tggctccggt accgtgtctg catcattgct taaaatcaat ttcccttttg
    78541 caaaggcaag tccgatatta aacgcgtggg cttttccttt atttttttcg atccgaacca
    78601 cacgaagatt agcgtatttt ttcatcagtc tagctaatat ttctggtgtt tggtccgttg
    78661 aaccatcgtc tgtcactaat acctcatagt tgtgataatt caatttcgtc atcaaatact
    78721 cgattgtata ttcgatcaca atttcttcat tatgggctgg caccatgatc gtgatgaacg
    78781 gttcgacact caagggaaca tctacccatt ctttttgctt atgtttgtat aaaaacacat
    78841 aacaccagac accaataaac catacaaatc cgcctaaaat cggataagaa acgagaaaaa
    78901 aatacataat agacaaacaa gtatctaaga ataaattacc tgtatgggtg attgagatca
    78961 tttcagttcc accccatttt ctttatacaa atctgcaatg aatgtcgtat ctagattttt
    79021 ctcttcggag acagaataaa aacggaccgt ttctctctct tcttttgttc caaaacgttc
    79081 cgtatacact tcttcaagta attcttgtct ttttttcaat ttttcatctt catattcaaa
    79141 agatttattt acttttttgt atagatttcg attgttccac ctagtcaata caaatgaggt
    79201 aatcaggaaa ctgaaaaaaa tcaatacaaa aaagccgatt aagaaataca gcattttctt
    79261 ttctgataaa aaagcgtaca aggaaaaatc cttggctctt tctggtctcg ttaatgggaa
    79321 aaagacccat ataaaaggaa gaacaacgat catccatcct aaaagagcca ctaacgtttg
    79381 ccaaatcttt aaccagtaat taccttttga aaaatactta tctttcacca aaattgatgc
    79441 aacttcttct cttgttactt ttttcatatc ctcacctcac gtttttttgt tacgacgtag
    79501 gagtttacca tacatttcat ttcttttcac ataaagtgtt cctaaatttt tcctaagaaa
    79561 aagaacaaaa catttctcat cagcaaatga aaaatatttt gttcttttta tcagttgttc
    79621 tttttatttt ttatctctta attatgttgc tctttccaat acgacaatgc ttttcattcc
    79681 tctagatatc gccgtgtaca tttgtctgcg tcttctttgc tcatctccat cgttttcaaa
    79741 tggatataag attacatgat caaattccag tccttttgct agactcaaag gaatgatttg
    79801 gcagttttct aatccatatg aatttttttt aatcgattct tgtagcgttt gggtttcctc
    79861 ttctgtttgg gtgataactg ccgctttttc tccttttaga gaaaccaaaa tctcagctag
    79921 tattttcaac aattcttcag aggatcgaaa agagcggtat tcgggttctt ttccttgcgg
    79981 tcggatcgat acgatgtcga tcttctcttg atccacagca taggttttga aaagctctgt
    80041 gattgctccg ctagaacggt aactatttct aagatcatac cgatggatcg gcagatggta
    80101 gtcgtcgaaa caacgcataa tatcagcaaa agtagtggaa gaattaaaga ttgcctgatt
    80161 ctcgtcacct actaaagtaa agtgagtttt tggaaataat tcgatcaata gacctaattg
    80221 tgccagggta taatcttgta cttcatcaat caatagatag cgaaatgctg gtacatttac
    80281 cttttcaaca agtaaatgac gaatagctaa tataatgact gcttcatcaa cagtacgtgt
    80341 gggttgccaa gcataagctg agccatatcg tttttcataa attctttcaa acaactgatg
    80401 ctcatccacc catgccattt cttcgatttg tctggttatt tttcgatatt ttttttgtaa
    80461 aagtttcctt gcataagcta caatactttg ttccgaatca tcagaaatca atttaccgaa
    80521 taattccaac tgcctatctt ctgtcaacga gagtacctga ttctgcacag caggactttt
    80581 tgcttgtttc aaaagatgat tcttccattc gctcatcagt gcctttttcg ttgcttgaag
    80641 cctatcgatc aatttaggat gagcaggaac tttctcatat attttttcga tcgttttttt
    80701 agaaaggact gtttttccat ttttagtaag tccacggata aaattcggat gatctaaaaa
    80761 caaaggatct gattgtttta gattatcgat aaactttttg ctacgcaaac gttctgtctg
    80821 ctccgataca ttttctcccg tgatacgttt gaaataagcc tcttcacctt ctatttcctc
    80881 tgctgaaagc tgtgaaacca gctgtatgat ggttagattc agtggatttc tttcacctaa
    80941 tgatggtagg acattcgaaa tatagtcgat aaaccgatga ttaggtgata gaatcagcaa
    81001 gtcatcggat gtcatcgtat ctcgatataa atagagcaga tacgcaatac gctgcatgat
    81061 agcagaggtt ttaccacttc ctgctacgcc atttaccaag atattttgac ttttcacatc
    81121 ccgaatgatt gtgttttgtt ccgattggat cgtagcagtg atagccttca tttcattggt
    81181 ctcatcttgg cctaagactt ctaataatac gtcatcttga atagctacag acgtatcaaa
    81241 aaacttgacc aaacgatctc tttccaaaag aaattgtcgt ctttctttaa taaccgtatc
    81301 gattttattt tgacgaaccg tataagaaga tggaccaatc atgttattgt aaaaaagttc
    81361 ggcaattggt gaacgccaat cataaacaag attttcatct gcatcatctg tgaaatttgc
    81421 tgtaccgata taaaaggatt cttttggctc attatccaga aagtctacaa cgacttttcc
    81481 aaagtaggga cttttcaata aacgttcgat ctttgctagc tgattttctg cgtttttctg
    81541 tttgatattc atctgatcga tttctctatt tttcatttca atcatcgaaa aagtatccag
    81601 gttatctaag taactgtcaa aattcaatcg aagctcgcca gccatttctt tcaacgactg
    81661 gtttccttct atttttgccg tatccatcga ttcccgcagt tcgttttttt tatcaattag
    81721 cttttgatac acgttcttca gatatgcttc ttctaactgt ttttgtgtgt tgaccataca
    81781 cattctcctc tttttttaaa gtggtggaac cgattagttt acctctttta agagtcgaat
    81841 gcaagctttt taacgagtat catttgttag gatatatcag ttcttcaggt cggacagttt
    81901 gatataaaga aaatgcacca tcaaggtttt ttacgtggta gccagactgc ttcaagattc
    81961 tttccgctag atagctacgt aatccgctat gacagctgac gatatattct tgttggctgt
    82021 ctaattcatt taatcggtcc cgaagttcat tcaaagggat atgtttggct tccttgaatt
    82081 tgcccttttc caattcttct gctgttcgca catctaataa aatttttcct tttgctagtt
    82141 ctgtcggcaa ttcatgccat tgtacggttt cactaagccc ttctgcaatg ttcattgctg
    82201 catatcctag catgtttact ggatctttgg ctgagccaaa tggcggtgca tacgtcaatt
    82261 ctaattccgg taaatcgaag atcgtcaaat gccctttgat tgctgttgct aaaatatcga
    82321 tccgtttatc cacacctttt gccccaacac cttgtgcacc ataaatctcg ccagtctctg
    82381 gatggaagat caacttcagt aaaatatctg ttgcttctgg ataatagctt gcatgatctt
    82441 ttcctgatac atgaatgact tcaaaagaca gttcgttttc tttggctgtt ctttcactta
    82501 aaccggtgga tgcggcagtc attccaaacg ttcgtataat tgctgttcca ataccgcctt
    82561 gatttcttcg agaaattccg gaaatcgtgt ccgcaacttg tctaccttga cgattggctg
    82621 gtgaagcaag agaaataagt gcatcttttc cagtgatttg ctgttttaca acgatagcat
    82681 cccccaccgc ataaatatca ggaatattcg tttgataacg ttcgtctact aggatacccc
    82741 cgcgtatgcc taattcgatt ccagcggtca ctgctagctg gttatcagga cgaacaccaa
    82801 tggataaaat aactaaatca gcagggatgg tacgcccatc atccagtcgc aatcgtttcc
    82861 cgtggtcttc aaatccagcg acagcatgag aagtaatcac ttctactcct tgatgagaca
    82921 attctttttc tataaaagct gccatttctt catccagtgt tggaagaata tgtggtgctt
    82981 gttcgatcac catgacttct aaacctcttc tttttaggtt ttctgccatt tccaatccga
    83041 tgaatcctgc accaacgatc acggcacgct ttggctgttt ttctaatgca tgcatcactt
    83101 tatcgatatc tggtacattt ctaatagaaa aaacattgtc ggcttctgtt atccctggaa
    83161 tcgatggaac aactggtttt gcaccaggag ataaaaccaa tgcatcgtac tgttcaatgt
    83221 gtttttgacc ctcatgtacg acttctaccg ttttgttttc gggaaagatg gctgtcactt
    83281 catgatttgg acgcacatct aaacaaaaac gagcggataa tgattctggc gtttggacaa
    83341 gaagattttc ccgttcactg atttctcccg aaagataata aggcaagccg caatttgcaa
    83401 aagaaacata cggtcctttt tcaaaaacaa cgatttctgc atcttccatt aatcggcgaa
    83461 gccgtgtagc agcagacatt ccacctgcta cacctccgac aataacgatt ttcatcttat
    83521 ttccctccta ctgttcgatc aaaccattga ttcatgccac cacgtacatt cactacatca
    83581 taaccagatt tctttaattc tttagctgct tgtttactcc tcatccctga ttgacaaatc
    83641 acatagacgg tcttttcttt gtctccatca tatctgttta tactttgtaa tggaacattt
    83701 ttagctcctt ttatatgccc gccccggtat tctgcaggtg ttctaacatc aagtaacgct
    83761 ggattttcca aaagcttttc ctttaattct gggactgtta tcgattttat tgattgaaat
    83821 agcaaattca ttttctgcac ctcatttaca tttttataaa tacctcatgg ggtatattaa
    83881 acaggagctt tattaatatg tcaaccagaa tgactcttca tttttttcac tactttttat
    83941 atttgcataa aataccgata aggggtatta tctaattata aaaatagagg agaatgtgtt
    84001 atggagattg ataataaaaa tatcctgaac cgtttgaaac gtacagaggg acaaattcgt
    84061 ggtatccaaa aaatgatcga agacgaaaaa gaatgtatgg atgtcatcac tcaattaagc
    84121 gctgttcgtt ctagtattga tcgcgtaatg ggcatgatcg ttgcagataa tctgaaaaat
    84181 tgctttgaga aacctgatag taatccagaa gaacaagcgg ctaaactaga acaagcgatc
    84241 aagatgatta ttaaaaagta aaggaatgat ttcaatgaaa gtcgttttcc atattgatga
    84301 attagaaaaa tggtcagaaa cagggaaaaa cgtaaaaaac ctgataaaag cttctccaga
    84361 aacgacgatt gtcgtatctg taaatggcat cgcgattacc ggttatctag actctgccaa
    84421 tgcagaattc ttagatttgc aaggagtcgt ttttcacgct tgcgccaatg ctatgcgtgc
    84481 taatcatatt tcagaaagtt ctttacctga acaagtaatc gttgtaccag caggtgtcct
    84541 tgatttagtt gaactgcaat cccaaggtta tgcttatatc aagccttagt cagtagaggt
    84601 tgcgacagaa gtgatcagct tcaagaaatt tcggcttatt tttcgaagaa gctacttctg
    84661 gaaaaccgtg aatcaaaggt tgtgaaaacg ctgtcctgca tcaagtaata agaacagcca
    84721 aacaaaaata gcttctcata tttttcgttt ggttgggctt attaccgcag atgcaagctt
    84781 ttgaacaccg tttaaggaag aggttgtgaa atcagcggtt tgacctaagt attagagaaa
    84841 aaaacgggaa aatagctcct catattttgc cgttttttga gctaataccg aaggtcagct
    84901 gattgaacac cgtttaagga agagattgtg aaaaagtcgc ttagtttcga gtattaagaa
    84961 aaattttgta aaaatggatt tctacatttt tgcataaatt tggcttaata ccgagaaact
    85021 ggcttttgaa taccgtttaa ggaagaggtt gtaaaatcag cggtttgacc tgagtattag
    85081 agaaacaaac ggaaaaatag ctgctcatat tttgccgttt tttgagctaa taccgaaggt
    85141 cagctgattg aacaccgttt accaagaggt tgtgagccta ccatttaact ccgaatcaca
    85201 agaaataatt tcaaaaacaa cttctcctgt ttttggttcg gttggcttat tatcgagaag
    85261 tagctactgg gagtctattt atcaaaaaaa ggaatgcgac ataggtcaca cccctttttt
    85321 attttctttg aaacatcttt cggtactcga cagcatacaa gacaaaagat tgtaaaagac
    85381 cgtaagtgat gacggcaaaa atgactctca cccacagcgt tggtaattct gggaaaagca
    85441 gcaaaaggat catgccaaca tagatgacag cagtcgctac tttgccatac cacttcgctc
    85501 cacttaattt gatattttta gatagcccga ttaatccagc tacaaacata aagccttctt
    85561 ttatcaagaa tagaccaaac aacagccaaa gccacggtcg ataccatgcc atagacaaaa
    85621 tcagaaaaag ttgtgtcaat ttatctgcaa acggatcaag caccttccct aagtctgtta
    85681 cctgattata tctccgagca atgaccccgt ctagataatc agacaaacct gagacaacaa
    85741 tgaccgctcc tgctatataa aatgactgtc tcagcacaaa ataaagataa atcggcagca
    85801 aaaaaatacg gaatatcgat aaaagattcg gaatcgtttg tatttcttta cgccagtctg
    85861 tgcttaattt cattttatcg ccctacctcc tcagcactct tttcttttta ttttagctta
    85921 cacggggaat aaaaccaatg atttcactgt ttttattttt ctttacagac actgatatta
    85981 tgagctaatt tgagataatc acttgctgtt ttcatcgttt actcttcttt cttcctgtcg
    86041 tttgcgcatt tcttttacta gtactttatg agcttttttt gatcctcgct ctaggtcacg
    86101 ctgccgttta cgtgttttat aatcgataaa cagactgtct aaatcgtaac ctgtcgggta
    86161 cagatcttct gctgaacgca ccagacgaac acgctgacga ggcacgtgga ttattttttt
    86221 gtctaaatat acatcaatcg tatcttcacc tatatcttca taaactaacg cttctttttg
    86281 gtattcattg acaaatatcc gatcaccttt tgcaaagagc tgacgttctt ttttattctc
    86341 cttcctattt gtaactgctg tcttaggaag aaattctttt ttctgtgtcc gataggcttt
    86401 ttccgccaag taacgctctg cttgatggat caatttcatc gacatatcca ttttatgagc
    86461 aatccacaaa gcttggcttt ctcctgtttc ttccaacccg caactgatat ttaggacgaa
    86521 gtgcttcccg atcgaaagcc atagcagccg gcacaaaatc ttcatgatct ccggcgaatt
    86581 tcttgatttc tccataatgg gtcgtggcaa tgatcaatgc cccttgctca tacatagatt
    86641 ccatgattgc gatcgctagt gcagcccctt catttggctc tgttccactg ccaatctcat
    86701 ctaaaagtac caacgtattc ctttttatct ttttcaaaat agcagcgatg ttttgcatat
    86761 gaccagaaaa tgtactcaac gcattttcta aattttggtg gtcaccgaca tcgacgaaaa
    86821 tctcatcaaa gacagcaagc tctgtccctt cttttgccgg aacttgcata ccgaacatcg
    86881 ccatcaaagt caataaaccg actgtcttca acacgactgt tttgcctccg gcatttgctc
    86941 cggtgataat caagcctcga tagtctttac cgatttcaac atccaatggt accgcatgct
    87001 caggtaaaaa tggatgtctg ccttgcttga taatgatatg ttccgattta ttgattctag
    87061 gtgtgcttcc attgatttct cggctaaatt ttgcccgagc aaagatgata tctaacaccg
    87121 tgatcgtttc gatcaataaa tcgatcactt cttcgttttc tgcgatagca ccagtcaatg
    87181 ccgccaggac ttgatattct tcactgattt cttcagcttt taacaactga tagtgttcat
    87241 tcaatttaga aatcacagtt ggttcaataa aaaccgtcgt tcttttattt gattcatcga
    87301 taatcgttcc atctatttta tttttatagc tggctttgat aggaatcgta tagtattcgc
    87361 ctttttgaac aatcattgct tcttggatca tttctttgtt tttcggatga cgcaagaatt
    87421 tcagtaattt tgactggatt tctttttcga ttagttgtaa ttgtttgcgt actttacgca
    87481 aattacgtga cgcgtcgtca ctgactttat tattttttat tttctggtca atcaactctt
    87541 ctacatttat caaatcagga agatgtttgc tataagcaaa caacaagggt gtctggtatt
    87601 gattcttatc aaaaaacttt gtgatcatcc gactgcttct aagaaaatcc gcatattcga
    87661 tcaaatcggt tggctgcaga atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc
    87721 tcggcaaccc cataaatgga acatgctgac tgctttctaa gatcaagcgt gcttctcttg
    87781 tttcttcttg acgatccaag acagtttgta ggtttgtcga gaccgtcata tcgctgattc
    87841 gttttttgct atagtttcca attgctcttg cttggatttc ctttttgatc cgatcaaatt
    87901 gtaattgact aatcatttcg ttgtccatat tctctccttt tcttgaagag atacctgtcc
    87961 caaaataaat aagggcctag agataaataa aaggatagaa cacagcttaa aaaagtcatg
    88021 tcctatcctt attagaatac aaagatattg ttttcctgac aggtaccgtt tcataagcac
    88081 accaaataaa ctttgtttat tggctattcg acttactgat tagataccag ctacactcac
    88141 aaaacatacc ccattcttct aggtcttatt tattttccac ttaactatag caagacacat
    88201 tttggttgtc aaactttagt atgttttata gatttacacc attaatgaat agacacctac
    88261 cgcgataatt gctccgatca ttggacctgc gattggtacc catgaatatg cccaatctga
    88321 agttccttta ttagctattg gcaataccgc atgtgctaat cgaggaccaa agtcccgagc
    88381 agggttgatt gcatatcctg ttggccctcc taatgaaaga ccgatggcta agatcaatcc
    88441 acctacagcg aatacgttcg ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc
    88501 aagaactaat acaaatgtac caattaattc tgtgatcaca tttgctggat aattccgtat
    88561 agcaggacct gttgcaaacg ttcctaaaat cgcgctttca tctttcgttg cattccaatg
    88621 tggcaaataa gaaagccaaa caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat
    88681 gatgaaagga acgacaagat tccaactaat tgcccctgtc atcgccatag ctagagagac
    88741 tgcaggattc aaatgagctg ggcccatgaa tccagaaata tagacagcca ttgttacagc
    88801 gagtccccaa ccaaatgcga tgacaatcca gccagaagcc tgtgctttac ttttgtttaa
    88861 attcacagcc gcacacacac catctccaag caaaactagg atcagtgtcc caataaactc
    88921 ccccatgatt tgagtcatat cactgttcat ttatttctcc ccctttagtt cccgcagatc
    88981 tgattctgca atcaatgctt ctaaacgttt agtctgttgc gccttctcct cttctgtcca
    89041 ttcaaaatat ccagcaattg catcgatcac aggttgcttg atctcatcaa gctgatctcg
    89101 ttcaaacaac agatgatttg tacgacgaat gagataatcg cctggggcca aaaccatttc
    89161 ttcttctaaa ccataacgta accgagctga ctcagcgaga ctcaaaccag gataaggtgc
    89221 catttctttt gctaattcaa agatacgtcg ggcattagtc ccgtaaaaat cagcgatata
    89281 agtagcatct tcttcctcta aaccggctgc tactccttct tttgctaatt ctgtcactgt
    89341 ttcttctaat ttagttggat cgaagtttcc acctgaaatc tgatattttt tagagtcgat
    89401 ttctttcgtc tctattccgt attcttcttt taataattgg cgtatcaatc gcaaagctcc
    89461 ttctgccatc ttacggtaat cggtgatttt cccaccagat aaagtcagca aaccatctgg
    89521 ttctctttct aaagaactac ctctggaaat cgtagaaggt gctttttcat cacggctgtt
    89581 ttccaaatgg ttcaacacgt cttctacttc agcacgagaa actttgtttt ccttatattc
    89641 acttactgta tcgacaactt tattgaagct cttgtctgaa atcgatccat tatctccacc
    89701 attgtaatca gaaccagaat taccaatcaa cagtggacga agtcctgccc agcttgcttc
    89761 gatatcattc aatgtgatat ttgcttctgg atagcgatga ttgatcacat ccaatagata
    89821 atctacatct tcttgtgtga ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt
    89881 cgtaccaaag taagtcttgt tttctcttgg aatagcaaaa accatccgcc catcttgctt
    89941 tcctgtatcg aagtatgtgg gttgcggtac aggcagtttt ttcgcatcta caactaaatg
    90001 gatcccttta gttggacgca ttttaggaga gactggacgc gtaaaattca agtttcgtac
    90061 tttatctacc caaggaccac tcgtattgat cactaatttt gctttgattt cgatcacttc
    90121 atctgtcagc aggtcacgag ctttgacgcc aacgatttga tcgccatcat ataaaaagcc
    90181 aaccgctttc attttactta ctagataagc cccatcttcg gcagcctttt tgatattatc
    90241 aatcactaaa cgggcatcat tgttgcggaa atctagatag acacccgcgc cttttagccc
    90301 ttcttttttc aaaaacggtt ctctttccaa tacttcttct ggtgtcagcg tataattctc
    90361 atatttggtt cctgtcacat ttgccagttt gtcataaagg tccattgcta ctttgaccga
    90421 gaacatattg aaggttgttg ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg
    90481 ttttgggatg tgtggggcaa tactttgtac gactgcacgt tcaccaactg tgtcagctac
    90541 tacttccaca tcaaatgtct tcagataacg aataccgcca tgaacaagtt tggtcgagcg
    90601 agaggaagtc ccttctgcaa aatcctgcat ttcgatcaat cctgttttga ttcctgatgc
    90661 tgctgactgg actgccacac cggcaccagt gattccgcca ccgatgatca acagatccaa
    90721 ttcttcttgc tgcatttttt gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat
    90781 ttcctcctta ttcaaatgct tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt
    90841 tttctcggcg ctcttcctcc atttgaactt caaatagctt gccagcttca taaaattcgc
    90901 ggatctcgtc tgtatctttc caataaccga cagctaatcc tgctaaaaat gctgccccta
    90961 gcgccgttgt ttccaagttt tctgctcgtt ggatcggtac attcaagata tctgtttgga
    91021 attgcatcag atattcattg tttgctgcac cgccatctac tttcaataca ggaatcttga
    91081 ttccagtgtc atcttgcatc gtatcgatga tatctctcac ttgataagca atcgactgta
    91141 aagtagcttt aatgatatct tcttttgtcg taccacgtgt caagccaaac atagcccctc
    91201 gtgctgcctg atcccaataa ggagcaccta gcccaacgaa tgcaggaaca acataaacct
    91261 catcttcgct tgtagagcgt ttcgctgcgt cttctgaatc gctagctttt tgcaacattt
    91321 gaagtccatc tctcagccat tgaatcgaag aaccagccac aaaaatactt ccttctaaag
    91381 catagtaaac ctttccattt atgccgtaac caattgtcgt caataaatta tttttggata
    91441 attgcggttt ttcaccggta ttcatgacaa taaatgaacc tgtaccataa gtattcttga
    91501 ccatgcctgg ttcgaatgcc atttgtccga ataatgcggc ttgctggtct cctgccatcc
    91561 ctgaaattgg tgcttcgctt ccataaaaat gataaccttg cgtataacca taaacttctg
    91621 agttagaagt gacttttggt aacatcactc gaggaatatt tagtaaatct aaaatctcct
    91681 gatcccaatc tagctgatgg atattgaaca acatcgtccg actggcattc gagtaatcag
    91741 taacatgtgc ttgtccatcg gtcagtttcc atactaacca agaatcgatc gttccaaaca
    91801 tcaattcgcc tttttcagct cgttcttgcg cgccttctac atgatcaaga atccagcgta
    91861 tcttcgttgc tgagaaatag gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt
    91921 gatagccttc attttttaag ttatctgcaa ttccagctga ctgtctggat tgccaaacaa
    91981 ctgcatgata gattggacgt cctgtatctt tttcccatat tactgttgtt tcacgctggt
    92041 tcgttatgcc aatcccagca atctgatttg gtttgatccc tgattcgatg aacgctccgg
    92101 caataactga ctgtacagaa ttccagattt catttgcatc atgttccacc caactttctt
    92161 gcgggaaata ttgcgtgaac tctttttgag aactgccgat gtgtcttcct ttcttgtcaa
    92221 agataattgc tcgtgagcta gttgtacctt ggtcaatcgc catgatatac gttgattctg
    92281 tcattgtgat tccctccatt atatgcaaac gctttcttta actactctta tcatactact
    92341 gttttaaaaa aagaaactgt caaaatttta ttcttttttt ctttttttga cagtttttta
    92401 ttatgaagct attttttaat caattctttt cttttttcag cgtctctatt cttcttttca
    92461 atcgaataat gtcgtaaggt gacgcaaatt ctgacagata atattcacac tgttttttgt
    92521 ttctctggca aaatgtgatc accaaatcat attctttacc ttcttcataa cttccaatct
    92581 caataccgcc gattcccctc agttctctga tcagatattg ttgaaaagca atacgataaa
    92641 tcggcagact ttctaaatcg attccaatca ctactggttt tgcaatataa aaatcgatca
    92701 tcaaaagaac attggcatac tggatcatca ggtaactaag ctcactatct tcagctcttt
    92761 tcctcggcaa ttgctgcacc gctgtttcct gtaatttcgc cagtaactgt gttaaggaat
    92821 gcccgagcat tttctgctgc tgttccaaaa gccgatcacg ctcatagact tcgatctttc
    92881 caacaaagaa aaaccattca ttgttgatct gggaaatttg gtagcctact gccttttctt
    92941 ctttgatttt caaacgacga ggacgataat gccataacat cgtttcccga atgtaagtat
    93001 ctaaaacagc ggttggtaac tttttgctcc gtgtcaaatc atactgataa aatatttctt
    93061 cgtctactat cgaaaaagaa acaaaaaagc tgtaaaacat cattgtttcg tatacattca
    93121 gttctgctgc tgttcgacta agatgcatca cgatgattgg atcgattgct tgataaagcc
    93181 ggtccgactg atagagtaat ttcttttctt tcaaagttgc gtacgtactt ttttcattca
    93241 atagtctttt tttcgtaatc ccgagccagc aagcaatctg tgcttctgct gatgccgtaa
    93301 acgttgtttc taatacacgg tccaatccta gaatgaacgg tcttttttct ggtgtatttt
    93361 gcaaaaaaag cggtcgctga tcttccggga tatattggaa tagttcataa taaaaatatc
    93421 gtatctgtag ctcttctccg tataattgac cgtttttgat ttgtaatcca aattcctcta
    93481 agagctggtt caattctttg atctttcgaa aaacagaaga ctcactgata ttaaacgctg
    93541 tcgctaatcg aacgatggat acttgctgat gttctaataa atagacgagc atcttaaact
    93601 tcaagctttc ctgcaataaa aacaatagaa ttttttccaa acttacatct tcgtccaaca
    93661 caagcagcgc ctgatactca tttcgctgta cttctacttt tttttccatc attcggccaa
    93721 tcaattcaat atcttccaaa tattgatcaa acgaggcttt tgacagttgg acatgctctc
    93781 tcaaaccatt gatagaggct gttccccctt gcagaacaag gtttcgcaaa atcaggatct
    93841 gtaactgctc ttttctttct aataatgctt caatcttcat aggcagtatt cgccaccttt
    93901 gaccacacca tatctggcac acggtattct ggctggaaaa atagctcatg ttcttctaac
    93961 tgttcaaacg tccatccttc ttctactgca attgtcagtt ggtcaagaag gtggaacatc
    94021 tcttttttgc tttggagctg tgctccaaga atcttttttt cagaatcaaa tagaaatttg
    94081 agtttaactt tgctttgatt tattgctgta agcttgtagt ctacgtatcc tgtttcaatt
    94141 ttttggggat aaaaaatgct ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca
    94201 aaccactgat tgccgactgg acgataggtt ccctgatcct ttgtctgtga gccactaatt
    94261 gtcttgctga catttcgtgc tgtacggaca gcgttattta ctagagaaac atacattttt
    94321 tcatttgttg gacgaaaagt tacttggatc gcatcgccaa tcgcataaac gtctttttga
    94381 gacgtttgca agtagtcatc tacccagatc gttccatcat cattcaatgt taattgttct
    94441 tcccacatct gattgtcggg acgagaatga ttagccagca aaacaagatc atagttctcc
    94501 tttctttttt ccgtctctac aatagcggtt tcattttcgg tcaaagacac aacttgttct
    94561 tctaaaaaaa gtgaaagccc ttgatttttc atttccttta ctaacggttc tgtcatttca
    94621 ggatctagat aacgaaaaag aattgacttt cggctttcgt aaagatggat ttgttttttt
    94681 cttgatgcca acccttcagc tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt
    94741 ttctttgcat tcatgatctt ttgctgaaga gccgttacgt tttgtatctt tttaactggg
    94801 tgaataagcg ttgattctgc agaaatattt cgaaactttt gatttgaacc agtcgctaga
    94861 atcaaacgat caaaatccaa tttttttcct cctgctaaaa cgactttttt ttctttcaat
    94921 cctattactg tcttttctgt gtaaacatgg attcgatagc ggtcagtcag ttcttctttc
    94981 gtgatccaag aaagttgttt ttcactggta acctttcctt ttaatatcaa attgaacccg
    95041 ctgggaatcc atcctaactt cgattgcttt tcaatcaaat atatttcact tgttggcatc
    95101 aattggcgaa gataaatagc cgcatgaatc cctgcaaacg acccgccgac aattacaatg
    95161 ttcatctgca ttcctctttc ttataaggtg ttctactgct aacttctcaa tcagaaaaca
    95221 cagtattcat aactcgcttt caaccttatg atacatagcg atgcagcaga atcaaccctc
    95281 tccatcatac cgtgttctag gtctgcttct caataatgta ctagtggacc taattgaaga
    95341 gtatcatttc tgaagagatg tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct
    95401 tttacgtacc tctgtccaaa taggaaacag aaaagaacga aaagacgagt tttagcgtgt
    95461 gtaatgtaat agttagaata gacacatcat ttatttttaa ttctttaatg cttcaacaac
    95521 tgcttcgcct aattgatgag cagattgagg attttgccct gtaagaagcc gcccatcaat
    95581 ttgaaccact tctgaaaaag ctgctccaga ctgatagttt gctccttttt ctttcaaagc
    95641 atcttctgct aagaatggta cttcattcgt tgtaccattt gcttcctctt cttcattact
    95701 gaacccagtc actgtacgtc cagctaaaat agattttcca gactcatctg taactggcaa
    95761 caatcctaca acaccgtgac aaacagctga gaccagccct tcatttcgat agatttgtga
    95821 agcgactttc ccaagatcta ttgcttctgg aaaatcccac attgttccgt ggccaccagc
    95881 ataataaacc gctgcataat catttgcatc cacatcatca ggacgtaagg tatttcccaa
    95941 ggcccgattt ctgaaatctt catcttcata ataggcccaa tcgatttcat ccatattcaa
    96001 aacactttgc ggttctaaag gtacatatcc gcctttagga ctgacaaaat ctgcatcgat
    96061 cccatttttt actaatacat cataaaaatg agtcagttca cttaaccaca aacctgtagg
    96121 acgctcgatc ttttcgtact tttctacatt tgttaatacg atcaatactt tcattttccc
    96181 atcctctttc tataaaaatt gcgttattga taacgtgctt tcaagaaatt atataatggg
    96241 cttggcaaat aaagctcttt atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca
    96301 cggttttcca ataatttctc tgcccagtca ggatcgacga tcatttgctg tccaattgct
    96361 gcaagttctg catatttcaa tacctgctct acatcttcgc gattgcggat cccaccgaca
    96421 ccaactaaag ggatctttcc ttgaatcgtg ttatggacca cttcaagaat cgatttatcg
    96481 ttgtatttat cagaacgagc tattcgatca tacatattta atgaaacatg cagataatct
    96541 agttttgact cacgtaatcg ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt
    96601 gtttcatatt cttctggtga gaaacgatac cctacgatga atggtttttt agcatattgt
    96661 tcaaccgctg agaaaaccgt tgttaataat tcttcaataa aacgataacg attttccaag
    96721 ctaccgcccc attgatcctc tcgtctattc gaatgcggag agaaaaattg ttggatcaaa
    96781 tacgtatttg ctccatgcaa ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg
    96841 gctttgccaa atgcttggat tgtttcaacg atttcttctt cactcattgc tcgtggtgtt
    96901 tccgcatcag gacgttttgc tgcaactgca cttgcagata caggctgttc tccagataaa
    96961 gttgctcgac ttgtcattcg tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct
    97021 ccttggattg ctttcgctag ctcacttaat cgaggaatca tttcatcatg agcgatgctg
    97081 agttcacctg gccagccttt tccgatatct tggacatttg cagcaccagt aataacagca
    97141 ccaagacctt tagaacgttg tttataataa gtgatctcat cttcggtgat cactccattg
    97201 aaaaagctga gttgtgtcgt cataggcgac agcatcaatc ggttcttcaa ttgaactcct
    97261 gaaggtaaag taattgattg atcaaattgt gacattgtca ttcctcccat aattcgctct
    97321 gattaaccta tcgagaatca tctatcatta aaccactcga ttagttgtac atgcaactaa
    97381 tttgcttaaa aaattttatt ttttttgtaa cttatctgtt gcatcattca ttgtctgggc
    97441 taattcttta cttgcttcat ttcccaaaac tgctttgtat gactgatgaa gttcttccca
    97501 gctaccatcg acttccttag caaattggcg tccttgttct gtaagataaa ctaatgacaa
    97561 gcgaccttcg ctaactgttt tgacgtatcc tttatattct aatttttcaa caaaacgagc
    97621 aatcgttgat ggggcggaat agagcatttg tgcaatatct ttttgtggta ttccatcttt
    97681 ttcttttaat atcaataaaa taaaaccata agttggtgcc agacctgtcc ttctaaacgc
    97741 ttcatcagct aatttattca acatgcgatc tagctttttc acgctaaaga aaagacattc
    97801 atctaacgct ttttcaattg gcttttccat ttcatcccct ccattggcgt acatatcata
    97861 gtatgatttt tattttttgt caaaaaacac ggaataatgt ccgcctcctc tgtctagatt
    97921 tgaaaaaaag aagtagccat cttcaaagaa tttcggcttg ttttcgacaa aactccttct
    97981 ggaacaccgt gaatcagagg ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt
    98041 ttgtgaaaat ggctttccac atttttgcat aaatttggct taataccgaa aaactggctt
    98101 ttgaacaccg tttatatcag aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca
    98161 gccaaacaaa aatagttcct catattttgt cgttttttga gctaatgccg atggtcagct
    98221 gattgtacac cgtttattga gaggtcgtga gcctgccgtt gaactccgag tcacaaggag
    98281 caatttcaaa aaacagcttc tcatgtttta tgactatggt gacttgtgat cgaggagttg
    98341 gcaggagaat actgtttatt cgtaaagaag gggctgtgac aagacttttg tcacagtccc
    98401 ttatttcctt ttattatagg atttcgccat ttgattggat gacttgtctg taccaatcaa
    98461 atgatttttt ctttaaccgt ttctttgtgc cattcccttc gtcatcttga tcaacataga
    98521 tatatccata acgttttgac atttgtgaag tagaagcgct gacgatatca atgcagcccc
    98581 acgacgtata accaaataaa tctactccat ctttgatagc ttccttcatc tgctcaatat
    98641 gctgcttcaa atagtcaatg cggtaatcgt cttgaacggt tccatcttct tctactttgt
    98701 ctatagctcc gagtccgttt tcagctatga acagtggttt ttgataccta tcatataatt
    98761 gattcaaagc aattctcaaa cccttaggat caatctgcca gccccattca cttgatggaa
    98821 gatacggatt tttaattcct ccagttatta agtttccttg gaccccttcc caattttctg
    98881 gatgagcact gactgcacta gacatgtagt agctaaaaga aacaaaatca acagggtagg
    98941 ctgctaagat ttcttcatca cctacttcta tttttaagtt gacacctttt tcttcaaaca
    99001 ttcgttgcgt atacgctgga taatatcctc ttgcttgaac atcactaaag aacaaagaag
    99061 ttctttgctg ctcaattgtt ttttgaatat catccggatc acaagaatac ggaacaagaa
    99121 gctgatagct gatcatacaa ccgacttgtg aacctttgat aatttcatga caagcttttg
    99181 tagctaaagc acttgctata aactgatggt gtgcaccttg gtatttcgct tgttccaaat
    99241 ggggatggtt ttcttcaatt actcctacgc taacaaaagg gtgatgtttt acacagttga
    99301 tctcattgaa agtcatccaa tattttactt tatttttata gcgtttgaat actgtttcag
    99361 cgaaacgaac gtaaaactga ataagctttc gattaggcca tccaccatat tctgtaacca
    99421 aatataacgg catttcataa tgggaaagag aaacgactgg ctcaatccca tattttagac
    99481 attcgtcaaa cacttgatca taaaaaaata atcccgcttc attgggtgtt tcttcatcac
    99541 catgaggaaa aattcttgtc catgcgatag acatccgata gcatttaaaa cccatttcag
    99601 caaataaacg gatgtcttct ttaaagtgat gatagaaatc atttccgtgt cttttaggat
    99661 aataatactt gctgttggga tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc
    99721 attgatctgt ccatttttct ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag
    99781 ataatccttt ttcatctaca tcccatgcac cttcacattg attggccgct gtcgctccgc
    99841 cccataaaaa tccttctgga aattttttca tatcgatccc cctaaacttg ctagttttct
    99901 tgtttgatta tttttcttat gactagtaat gatatttttg aatctactac tatttgtaac
    99961 aataaccatt gtggtcggat catatccctc tttgattaat tcttgcaaat ctacttccat
   100021 caataaatcg cctttacgta ctttttttcc atcagatact gcactttgaa agtatttgcc
   100081 atttaaattc actgtatcaa taccgatatg gatcagtatc tctgctcctt cttcactgac
   100141 taccccaatt gcatgtttcg ttggaaaaac tgttgaaact tccccgttta cagaactgta
   100201 gatttttccg tccgttggaa tgatcgcaaa cccttctcct aaagatccac tagcaaatgt
   100261 tggatcgttt acttcagata aatcaattat ttcacctgct gcaggagtac ttaacactat
   100321 atcctttgag gattcttctt cgatttcatc cttgtagccg aaaagaaaag ttagcataca
   100381 ggaactgatc atcgctaaga aataactagc aactagccaa acaaatcctt caccaatata
   100441 aatcgggaaa gacaaaatac ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc
   100501 agctactcca ccaaatatag ctccacatat acaagcaatg taaaatggtc gtttatattt
   100561 aagagtcaca ccataaacag caggttcagt gattccaaat aatgctgtga taaatgcaga
   100621 taaagataaa ctttttactt tcttattttt cgttttcaaa aataccccaa gtactgctcc
   100681 tgcttgcgca gctacggcag tcatacatgc tggacctagc gtatcacgac cgtagaaaga
   100741 aagattgttg gtcattactg gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg
   100801 ccaaaatccg ccgataacag caccagataa aacagggcta aagttataaa cagctaaata
   100861 tccagctgca atcagctgac ttgcataatc tgcaattgga cctacaacta ataaaataat
   100921 tgggaccatc acgatgatac aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa
   100981 gcttttgcga atcttaggct caatataaga aagaacccat acagctaaaa ttgctggaat
   101041 aaccgtactt gtataccttg ctagaatcac gggcatccct agaaatcgca aggttatgct
   101101 atcactatat gcactgacaa tcgtaggata aacgagagct gctgcaataa ccatagcgat
   101161 gaaacgatct gtattgaact tttttgcagc agtatatgcc aaaaatatag gcaagaaata
   101221 gaaaaatgca tcagctgctg cattcaaaat gatataagtt cctgattcag tagttaataa
   101281 attcaaactc gtacataagg cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc
   101341 taaagtcggg gcaaaaacag cggcgatcat gtctataaaa gagtttaaaa tgcctttttt
   101401 ctcagttcct ctctttccac tagatgcatc atcttctagt ttcatttgtt tggataatac
   101461 gtcatacact tcatttactg catttcctac tacgacttga aacattcctc cagcttcgac
   101521 tacagtgatc acaccttcta gttgctctac cttctcctta tctgccttct tattatcttt
   101581 tagggtaaag cgtaaccttg ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc
   101641 gacaaatcgg acaatatctt tcgctaattg tgaatagtcc atttttactt cccccttgtt
   101701 aattaatgcc gtagcaatcc ttcttacaag ataagtatag ttcttagaaa acggtttctc
   101761 cattcaatta gtaccccttc taatagcgaa cgaaactgta caatagtgtg tatggtttac
   101821 ttagccgagc aaatcactca ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc
   101881 aaaggagaca aaaaaaacac gcttgatctt cctttgctga tgtataagtg gtatctcaag
   101941 ctgatactct gtgatttttg tttctacttg gcttttgata agacagcaca acaaagtctc
   102001 ggcatttaac ggaagcataa ctaggtcaga actaggagag attagttgct gaatggaatc
   102061 tatcttttta tggattttta tttgattttc ttctttgtag taatgatcaa gcagttttgt
   102121 tttctttttt tcttcaacta tggtcagctt ttcacgcaaa atctgataaa tctcccaaga
   102181 ttcaaactca tctagaacac taggtagata aatcaaatca tcccactcaa aaataagctc
   102241 ttgctcagta gtcaaaattg catcatattc cgttattttg tttgattgat ttttgaaaag
   102301 atacactggt tctatccggc attctttgat ccacatgttc atactttgtt gaatctgttt
   102361 ttttagtgta ttcaaaatac taattggctg gttactaaca atcagtatct ccccttgttt
   102421 tcgaaaagga ttcaacgctt cggcaagata caaaacaaaa taagcgcttt cagctaaatt
   102481 gggacgtaat tgaaaatgta ttgggaagaa acgccgaatt aaataaattt ctaaaggata
   102541 acgggagatg atcttttgta caaaatgatt catggtatta tgtccggcat ccatcctcgt
   102601 tttcatttgt ttgatatggg ttagcaaaaa ttctgtttca tggaacaata acgaaacagg
   102661 aagatctaaa aaacgaataa tcgtttgctc aaatgctctt agattcttct ctatttcttt
   102721 gtttttttca tcattaatca tcaaataatt taactctaat agtcgatttt caattgcttg
   102781 tttttcttga ttggaaaaag aatagggtag ttctgatgat aacttttttg tgagggtctc
   102841 taccatcgga ataaataatg tatacctgtt tgttttttct aaaagttctt ctcttcgaag
   102901 aatggtcaaa acgagatacc gagaaaatcg tatgaagtcc tctcctgaaa caatataatt
   102961 atatgatata agaacctctt ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat
   103021 tgtactgatt tgttgaggca accttgcgtg ttggatcacc gtttctgttc caacaagaga
   103081 taagaaaatt ctttttgaat tttcttcagc aatgattttt agtccttttg tcgacgaaac
   103141 ttccagttct aatttaggat tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga
   103201 tacggctgtt tttgaaagaa agaaaatgtc tgctatcttt tgcatactga catacccttt
   103261 ttgaaacaat aagtacgtca caatagttga agctcggaaa tccatgctgg aatagatttt
   103321 atgtttcgtc acctcttgta tgatttgctg tttagtttca gattcaattg attctaaaaa
   103381 ataacctgaa cgtttatttg actggataat gattttcttc tcgtagatag caagcatatt
   103441 tttgatttca gtttggatcg ttttcttgtt ggtacctaaa gcttcagcta attcttcgct
   103501 tgttatccaa tgattcttat ttcttaatac tacaagaatt tggagttgtc gtttatttaa
   103561 gtccatttgc ttacacctcc tctttgttat aaacatacag gaaaaacctc tcaaatgaca
   103621 atagtcactt gcagaggttt aaaaatcatt tgaagaaaga tctatattca aggtttttac
   103681 cattagactg gataatttgt ttataatatt caaaactatc ttttttcaat ctcctaaagc
   103741 ttccgctccc atcattttgt ctatccacat aaataaagcc atatcgcttc ctcatttccc
   103801 ctgttcctgc cgatacgata tcgattggtc cccaccataa gtaaccaatg atttggcaac
   103861 catcttttat tgcctcagca atttcctgaa gatgtatttt tagatactca caacgttttg
   103921 gatcgtggat tcgattcaat tcatctggtg cttcatctag tccaatgcca ttttcaacta
   103981 tgaataatgg taattcataa cggtctgtca attcattcat gacataacga aaccctagag
   104041 gatcaattgg ccaactccaa ggttcgggag atttttcctt caaaaaggga ttatcgaaac
   104101 catttgctcc gccagtatct acgcgcattt ctgcttcttt tttatagaca gcgctacgat
   104161 aataactaaa tgcaatataa tctgccgtgt tagcttgcaa gcactgttcg tctccatcta
   104221 acattactgg tgcacagtct tcttccttcc atgtcctgta aatataagct ggataatgcc
   104281 ctcggcacat gacatcggag aaaaaccatg aattgcgttt aaattgcagt gaaccaaata
   104341 cattctctgg atcacagtca tatgcataag tcgctaatgc agaaaagcta cacataatac
   104401 ccatcttagc atttggatcg attttcttta ataattgagt agcacgggcg ttcgctagaa
   104461 acatatgatg acaggcttga taaatcactt tttttgttag tgtagcaatg ggttcaagtt
   104521 tatctctagc agggaatgta accaatccag cagctgcata aggcatacga aaagcattat
   104581 tgatctcatt aaaggtcatc caatatttca ctttcccttg gtagcgttca aagacggtct
   104641 gcgcataaaa ttcaaaaaag tcgattaatt ttcgattttg ccacccccca tactctccta
   104701 ccaatgctaa gggggtttca taatgactaa gagtaattac tggctcgata tcatatcgat
   104761 ttaatgtatt gattagtctg tcataaaata cgagaccagc ctcatttggc ttctgttcgt
   104821 ctcctcttgg aaatattcgt gcccatgaga tgcttgttcg aaaagctttt aaacctaact
   104881 ccttcagtaa acgaatatcc tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa
   104941 gataatggag tgattcgtct aaagcaatct cccaaatctt tttttcttca ttccactgaa
   105001 tactaggatg ctggttcatg atcccgataa gcgtatctgt cacattaggt aatttgccgt
   105061 cttccaacca tgcaccttca cattgattag cagctactgc tccgccccat aaaaaatttt
   105121 ctggaaatat ttcctgatcc ataactatct ctcctcgcta tcaacaattt cttacttgaa
   105181 gtatagctcg attcatcaaa acaagatatt ctaactattt cggcagaaga gaagaaaaaa
   105241 attgaatgct actcttcatt tttaatattt atatataaca aatacataag acgatccccg
   105301 aaagaaaaca ctcgttaacc atctaagcaa acgatttatt ttacttccaa cacaaatgct
   105361 tcataaggtc gtaaatcaac tttgccgtct ggtaactgtt tcagaggata atttgacaca
   105421 ataaccctta aagcttcacg tggaatagtg aacgtctgct tttcactgga catattacaa
   105481 ataacgagcc attgctggtc ttcatatatg cgagaatagg caaagacatg ctcaggcgtc
   105541 ttttccacta attcatagtc tccccagacg atgatgtcat gttttctacg caaatcgatc
   105601 aatttcttgt acatataaaa aacagaatct tgatctgcta acgcttcttc tgcattgatt
   105661 tctttataat ttggattgac tcgaagccat ggaattccag tagtaaaccc agcatgttca
   105721 cgggcgttcc attgcatagg cgtcctagca ttgtctcttc ctttcgcctt gattgattcc
   105781 aagatttcct cttttgtaaa tccagaagaa atcctttcgt tatacatatt gattgtctca
   105841 atatcttttg cttccgcgat atcatcgatt gggcaattcg tcatgcctaa ctcttctcct
   105901 tgatagatat aaggggtgcc tttcatcata tggagcaaga tagcaaacat cttggcactt
   105961 tcttttcgat acacatcgtc atttccccaa cgagaaacaa ttcgcggaag atcgtgatta
   106021 ttccaaaata aactattcca tccttcatca cctaaagatg tttgccattt ggataatact
   106081 tttttcagtt cagagatact caagggtttc aaatcccatt tgtctttgcc ttcttgctga
   106141 tctaatccta tgtgttcgaa ttggaagacc atggataatt catttctttt aggattggaa
   106201 taaagtttag cgatttcggt agttgctccc catgtttcgc caacagtcat cagatttttg
   106261 tcaccaaaag ttgcttgatt catttcctga agatactcat gcagtttagg tccattactt
   106321 gtgatttctt tatccggttc tttgccaatc atatcgatca cgtccatacg aaagccccca
   106381 atacctttat cgatccagaa attcatcatt tgataaatct cttggcgaac ctgtttattt
   106441 ttccaattca aatcaggttg acgcttgcta tacaagtgca gaaaatattg ccccgttttt
   106501 tcatccaact gccaagcaga accactgaat attgagcgca atctattagg ctcttttcca
   106561 ttgaccggat cacgccaaat ataatagtcc cgataaggat tttctttatt tttacgggcc
   106621 tcaatgaacc acggatgttc atcagaagta tgattcacca ccagatccat gatgatacgg
   106681 atatttcttt tctttgcttc ttcaatcagt tcttccattt cttccatcgt accgaattct
   106741 gccatgattg cttgataatt actgatatca tacccattgt catcattcgg agactcgtat
   106801 actggagaaa gccaaattgc atcaatacct aaatacgcca gataatccaa cctggaaata
   106861 atcccccgca aatctccaat accatcttga tttgaatctt gaaaacttct tggatagatt
   106921 tgataaacaa ctgaatggtg ccaccatttt tgttccatga ttttcctcct ataaatggat
   106981 gtttctattt tttgcttaat catttatttt agtctctctc actaaaaatt gtaacgcttt
   107041 caaatagcta ttgcaccttg ttatcggtaa cagaataaaa caaaaaaaca gctgaggaaa
   107101 ttccctcaac tgttttttga aaggattgat ttatgcaggg aagaatgctg atttcacaac
   107161 ttctttataa acggtgttca ctcagctgtc ccttggtatt agctcaaaaa acggcaaaat
   107221 ataagaaact attttttcgt ttttttctct aatactcagg ccagaacgct gatttcacaa
   107281 cctctttatt tcacattcaa tatccacatg aatcccacaa atacaaagaa cagaccatac
   107341 atgattggag atacttcttt tcctctttta gctgctaaca tggtaattgg atagaagata
   107401 aaacctaatg caatcccatc tgaaatacta taagtcaaag gcatgccgat caagatcaag
   107461 aatgaaggga tcgcaatctc taagtttccc cattcgattt gtcgcaaaga ttgtgccatc
   107521 aatactccta ccataatcaa tgctggtgca gttacttgtg aagtaacaac tgatagtaat
   107581 ggagaaaaga acaagcctaa caagaagaaa atccctgtag taatagctgt gatacctgaa
   107641 cgtcctccaa cggcgatacc agctgatgat tctacaaatg caccaacagg agaagtacca
   107701 aataaggaac ccgcaagcat agctgttgaa tcagaagcta aagctttccc tacacgaggc
   107761 atcttgttgt ctttcatgaa acctgcttgg tttgctaatc caactaaagt tcctgctgta
   107821 tcaaagaaag tcacaagcaa gaatgtcagc actacgaccc acatttgaag agaattgatg
   107881 tcccctacat gttttaatgc aactaaaaat gttggtttca aacttggtgc tgcggcaaca
   107941 atttcagaag gcattggaat caaacctgtg accagaccta aaatcgttgt agctgccatc
   108001 ccgatgaaga tgccacctgg tacacgccga acaagcaaga tagcagttac gactaatcca
   108061 aaaatcgtca accaagtaga accaacgttg agtgatccta atcctactaa tgtagattca
   108121 ttcgaaacga tgatcccacc ttcgctcaga ccaaggaaag cgataaatag accgataccg
   108181 ccagaaatcg catatttcaa atctgctggg atcgcatcaa tgatcatttc ccgcagcttg
   108241 aagattgtga tcaaaataaa aatcaaagaa gcaacgaata cgccggctaa tgctgtttcc
   108301 catggaatcc ccattcctaa acaaacagaa taagcaaaaa aagcattgat cccaagagca
   108361 ggtgccgttc caattggata acgggctaat acccccatta aaacacagcc gatcgcactg
   108421 gctaatgcag tcgcagtaaa cactgctcct tcatccattc cagaagcacc taatacagtt
   108481 ggatttacaa ataagatata agccattgag ataaatgttg taaatcctgc cagtacctca
   108541 cgttttaccg tggtgttcaa tttttctatt tcgaagtagg aaagtatttt ttccttcatc
   108601 ttccatcccc ctaaatccga acattataaa taaagtccgt taaaatttcg atttattaat
   108661 aaaacaacgt gttttatcat atactaaaac aaaacataag taaacaaaaa attcggattt
   108721 taagcaaaat ccgaacgttc catctgatta aatcccttta tctcaaagtt catgaacatt
   108781 cactttggat tacaagaatt tctttattgt gttaataaag tttcttcatt ctagtctcaa
   108841 aaatcaatag tgtgatttga ttttaccatt tcgtttctgt tcttctttga tgaattcttt
   108901 tgtatcgaca ggattcagat tatttagtcc gccaaaacct gtatcgacca tttttcccca
   108961 gccttttgtc ttcttttttc ctgatttgag attctttgct cgaagcttct cactatgttt
   109021 tgctcgccga tacttcaaat aaccttctaa tcttcccatt agatccactg tttttcctcc
   109081 tttttattca atcagacgac tcagctttcc ctataacaaa ataattgcct tcagggtcag
   109141 aaaaattgaa agtcaagatg ccattgttat ctgtgatttc tcctggttct tccatgttct
   109201 cgtagatagt ttcaaattca tccgtaaaaa atactaaaga aggcggtggt cctaatacct
   109261 ctggtgaaaa cttctgcaca aatacttttg ggaatacgcc taattctaat tcttttgaga
   109321 tgctgagtac aatactctta aattcttctg gcaattcgat tgtttcagaa atttctgcac
   109381 caattttttc tacaaagaat cggcaaatca tctctacgtc attgacataa agcatcacac
   109441 gtgttttttg tatcatcatt tgacccttct ttctatttga ttttctttcc tgtctataaa
   109501 ctgattccat tatatcacga aagcgcaaac accttgtgtt tgatactatt caagaaaaat
   109561 aaagcaatag tttctaggat tgctttcctc cacaaacttt ttttacaaaa aaaaaaacgg
   109621 caatgaatgc cgctcttctt atttcgattc ttttataatt ctgcttctga ttcatctttg
   109681 gttagtgtgt gtctaacact agttacgcca aatgtttgat cgattttttc cttcaacgct
   109741 tcgattgcct gtgcgccacg tgccgcttgt tcagcattga tggattcaat gaccagcacc
   109801 gctgcttgtg tttcttccgt cagcatcgtt ctttgggctt cacgccagtt gagacagcga
   109861 cagatcgctc cttgttcatc atagtagatg atttcttccg gaagtgccgg agcatcggaa
   109921 tctgcaccta aaggcaggaa tgattcgcca ccttgggctt ttcctaaatg cagatttcct
   109981 gcgatctttt cgatatcttc tccgccgcaa ggtacgccaa aagacaagga aatactatta
   110041 tagatatcta caagcggatt gattgggaaa aattcccgtt cttgatttgc acgtttcagt
   110101 aaagcttcaa tagaagaacg tgcacctttt ttagtcttga atgtggtaaa tgcctgacgc
   110161 cactgagcaa tgacttcgtt ttggctgaat gtttcttctg taaggtaatt tcttgcttct
   110221 tttgctgcct cattcaataa ttgatgatac gtttcttcac tttcttttgt tacgtggtta
   110281 tcgataccat ttacggataa gatttcgatg gttgcttcag gaaatacttc ccagaaattg
   110341 gtatccacta ttactttttt catctgttca cacctcttga ttagaataat tgcttgatga
   110401 atagatagtc tgtttgggga tcatctccca tataaaaaac atgttcgctg tatttgataa
   110461 atcctttttt acgataaaaa gcgagcgcaa catcgttgtg ttcccaaaca ccgagccaaa
   110521 tggctgtttt ttgcttttct tttgcttttt caatagctgt atctagtaaa aatgtaccga
   110581 taccttgatg tttaaatttt tttcgtacat agattcgctc gatttctaaa aaatgatcag
   110641 ccatttcctc agattgactc gttcctgtat ttagtttcag gtaacccgca ggctcttgat
   110701 cgatactcac taggaaaaaa tcggtttctt tatcttttag ctcttctgta agtttttcta
   110761 gtgcataagc ttgtgtcaag taatcagcta aatgctccgg tgaattatct tttccaaatg
   110821 tatctgtaaa tgtttcgata ctaatttgtt gtagtaagtc tacatctgaa ggcgtcattt
   110881 ttcgaatttc gtatttattc acggcttctt cctttcaata gatcctttta ttgccttttt
   110941 tgacaaaatt ccaatcttcg ctaacattct tgcatacttt atttaaaaga tattccaatt
   111001 gttttgcttc ttcgtcagaa agaccattta atgcgactgc attggagtag ttgttttctc
   111061 gaatgatgaa aggatagatt tctgctcctt ttttagtcgg atagagtttc ttgatttttt
   111121 tattttcttt atcttccaaa cgttcgatca tcccattgga ttctaatttc ttgattgctc
   111181 gggcagtcgt tgtacgatct actttgatca tttctgctag tttttcttgg atgattccag
   111241 gattttcgca aatacgtact aaataaagat actgtcctct tgttaaatcg acttctttga
   111301 attcgatatt gctaatagaa tctagcgctc gggcaatcat tccgatgtct cgaaggattt
   111361 cagccatttc atcccacctt tattttgttt gtaagactag ttcacctctt tttgttgcaa
   111421 atgcaactat tttcaataaa aaaatcaagt tcttttttaa taactagtaa agtatattct
   111481 tttcttcttt tacgaaaaag ctcaatcaca atagatctgg tttttgtttt ctaaaataag
   111541 taactgtttc ttcgttgttc gcttttctga tagctttggc aactcttcta tactaaaaaa
   111601 tcccatgttg gaagtttcat tattctcaat aaacttggcc tcttcaccgt ggatcgcaca
   111661 agcaaaaaca agtttataat actgaaaaag ctgtggaata tctttttgtt tattcgtatc
   111721 aaaaactgct cgcaactgag tagtttctac tgttaatcct gtttcttcat agacttcttt
   111781 acgcacattt tcttcaggag acaatcctat ttcagcaaat ccaccaggaa gtgaccattc
   111841 tttcgtccgt ttatcttcga ttagtaggac cttgccatct tttttgatat aggcacgaac
   111901 atctactttt ggtgttggat gtccttctcc aatcgttgtg agcgctttta tttcttcgaa
   111961 agtttctttt cctatttcac tgattagttc caatgaaatc gtccggatct cctcaaaacg
   112021 ctctttatca aatacatctt ttccataata tagaccagct tgagaaagtg cgagtagtct
   112081 tttgtattga gccaacttct tgttcattct cttcccttct tttttagcaa atgtatgact
   112141 atgtaatcaa gtatagaaga ctggtttaat tacggcaaat aaatataatg aaatctgcaa
   112201 taaataaaag aatgttaaaa aactcgagaa caaaagacat tcgacttctc tggggctgtg
   112261 aataaatggc gttcaaaagc ttgcatctgc ggtaataagc cccaccaaac gaaaaatatg
   112321 acgagctatt cttgtctggc tgttcttatt aattgaggca ggacagcttt ttcacaacct
   112381 ccccactaaa cggtgttctc ctaccaactc ctcggtcaca agtcacaata ttcatcaaac
   112441 atgagaagct gtttttttga aattgctcct tgtgactcgg agctgaacga caggctcacg
   112501 acctctcggt aaacagcgtt caaaagccaa tttttcgata ttaagccatt tctttgttac
   112561 ttattgtcat tgatttcttt ttctaattta tccaatagtg gagtgtaatc cacttgagta
   112621 tagtctgtta catcaaattc atatagtgtt cctaactgga atttgtcata ttttcggtcg
   112681 gcgatgatct ttttgaatgc ttctttcgta atatgattgg tccctttcgt tcgatcttcc
   112741 aatacgtcac catagtgata atgatccatg atatagctca aatgacgatc tgattcacga
   112801 tcacgtttgt accgacgttg ccataacact tcaaagtctg ctgttaggcg aatcgtgatc
   112861 acctgatatc cgtatctatc tgctaattct tggagtcgtg ctttttgctt atcactaaaa
   112921 ggatactcgg acacaatcac tttctttcct gcttccatat acaaatcaag tgctttgtaa
   112981 tagaaaggat aaactttcgt cctttcttgt tccgcccgtt cttccaaatt gttaaacccg
   113041 atggattctg catagtattc cttgatttca tcgagcgtga tggcatacat atctggaaat
   113101 cgttcccgta gtttattcat aagatatgtt tttcctgtac caggactacc agccagaaga
   113161 atgaaatact ttttcatctc atttatttcc taagttaatt ggactttcca agttcataaa
   113221 cagtccaatc ttatgcttga caatttcttt tactgcttca tttgctggaa tcacattatg
   113281 gcgaagagac ttgttgattt ctgtttcact aaaggtttct ttagctactt tcgtccagtt
   113341 gactaaaagc tccgttccaa cattgaattt gcggatcccg ttattgatca attcaggata
   113401 atcttcttct ttcacacctg ttcctccatg gataactagg gggacatcaa ctactgcatc
   113461 gatttctttc agcaagggaa tgtttacttc tgtttttgat ttgaattgtc catgattcgt
   113521 accgatagca atagctaatg catccacgcc tgtagcttct acaaatttca ctgcgtcttc
   113581 cggtcttgta tataccttgt cattttcagc gacatggatt ccttcttctg taccgccgat
   113641 tgttccaagt tctccttcta cggaaacacc gtgcgcatgg gcatattcta ctactgcttt
   113701 tgtcttcagg atattttctt tgaaaggcag atgggaccca tcatacatga cagaagtata
   113761 tccgctgtcg attgcttctt tgatatcatc aaagtctcgg gcgtggtcta agtgcaagac
   113821 tgcatcaacc atttcttctt ctgcaatagc tgtcattaca ttgactaaca catgcatgcc
   113881 gatatattta gcggtatcga cacttgtttg aataatgatc ggcgaaccca tttcttttgc
   113941 tgcgcctagc atagcaggaa gcatttctag gttatgcgta ttaaaagctc caactgtaaa
   114001 attcaactct tctgctgttt ttgttacttc tttcaatgtt gtatacatct tttattgcca
   114061 ccttatcttt ttatttgttt cctttgatcg ttacttgttt tgcaatttgt cgcatctcat
   114121 ccattttgcc catgtagtaa tcgatccctt gatcatcacc agcacgagca gcatctgcac
   114181 gcttctggtt atagaggctc atcagttttt tatacccatc tccgatcgtc tgtttatttt
   114241 ccaaactctt ttctaaatat tggatggctt gatcgttcac atacaattca gaaaatttaa
   114301 gtccaacttg ttcataaagt ttcgctaatt tatgcttatc ttgggtagtg gaaatctctt
   114361 gtttcaattg tgtaatctct gattgaatct tttcggtcgc ttctggcgat agggcttttt
   114421 cttcttttgc cagaactttt ttcggttctt tttctttttt cttaaaaaat ccaaacatca
   114481 ttttccctac tttcaattaa aatgctttca aaactgggct taagatccag gcatataaga
   114541 gtgctgcggc tactgtatct acatcggttg ctgtagcatt gatgaatccc atcgaattaa
   114601 agatcgttac tagcaaagcg ggcaataatg taataaagaa accatgagca ataccgccaa
   114661 tgatcgctcc tcggcgtccg ccaactgcgt tgccaaatat ccctgctgtc cctccggcaa
   114721 agaaattggt tagcatacca ggtaaaatca tcgctaagcc gaacatgggc aaagtaaaca
   114781 tggcaataat cgtaccaatc gttgtcgtaa tgaaacctaa aatgacagca tttgggctat
   114841 aaggaaagaa aactggacaa tctaaggcag ggatcgcatc aggaactaat ttcatagcta
   114901 tccctcgaaa tgccggcacg atttcaccta acagtagacg tacaccagct agcaatacat
   114961 acacacccac tacgaattgg atggcttgta aaaaggcaaa catgatatag ttttgatctc
   115021 ctgataattc agaagcgaat ggttcgcctg caaataaaac agtgatgata tatagcggga
   115081 ccatcacgac catgacagac aaataagtat cttgcagaaa ttcgaaatgt gtcggcaact
   115141 tgatatcttc gatcgacttt ttattttcgc ctttctcacc aaaaagctta gcaacaccgg
   115201 cttcaaataa gtacccgatc gtacaaaaat gacctaaagc aatatcattt gatccagtga
   115261 ttttacgaat gatcggttgc gctactgccg gcatagcaat ggcgaaacaa gctccgataa
   115321 aatcaccgac caagatcaat acgatccctc gcagaccggc aaaatagcca aagactgtcg
   115381 tcatcgttgc catccataaa attgcttgac cagttaaaaa aatgtacttc cattttgtga
   115441 aacgagccaa aataatattg aatacaaaaa tggctaagaa cgtcagtgca atatctctac
   115501 ctaaacccaa atcattcatt gcttgaccat tgatagattc aatagaaggg atgatccctt
   115561 gcatatgaaa tccttcagta aagattttcc cgaaataagt taaacttcca acgatgatgc
   115621 tcgaaccggc actcaacact tgaaatccta ggagtgtctt taacgtgcca gagatgactt
   115681 gtcctgctga tttcttctgc agtagtagac ccaacatagc aatcaatgca atggtgatcg
   115741 atgcctgagt caaaatattt tcgatgataa aattgataac gcccatgttt ttaccctctt
   115801 ttctttttgt atttagataa ctcccttatc ttgcagaact ggggtgattt tttcttcaat
   115861 ttcatttttt gaaacaatat ttttcaaata gatcatcgcc gttttaggat caactgcgaa
   115921 cttttcgaac tgcgaacgaa aattttctgc tgtgatgatc acatctggtt tcatggaaac
   115981 tgcggaagaa atatcacaat ggtccagttt ggcttctact cctaatttgt tcaaaacatc
   116041 ctcagcagac atctgtgctg caaaactact tcctaaacct gcaccgcata cgaataaaat
   116101 gttcaatttg ttcatctttg ttctcccccg tatcatttat tatttctcaa ctactgaaaa
   116161 aagcagttgt ttgaaatctt cgatatttgt gcattcaatc aatcgatcca acttctcttc
   116221 gttgttgatc aattcaatta gttctttcat gatgttcaga tgcgagtagg agtctactgc
   116281 tgccaaacaa aaaataatct ttactggatc catttcagga ttaccgaaat cgattggttg
   116341 ctcaatcgta gctacgctga ctcctaattt attgacccca tcttctggtc gggcatgggc
   116401 tagtgccatg tgtttgccaa tcacgatata cggtccgtaa tcattcactg cacgaatcat
   116461 cgcttcgaca tagcgctctt cgacaatgtt ttctttaacc aatggtctag cagctagttc
   116521 aatcgattcc tcccaagtag tggctttttc tttgatcatg atattgctgt ccgtcaaaat
   116581 atcttttaac ataggctgga tctccctttt gttgatttct aaattgtttg tttcgaataa
   116641 tttttctaac ttgccataga tgattcgatc tactcggcca ccactttctt tcatgacatc
   116701 tattatttga gtgaataact ccgtcgattc atgactgtta ggctctaacc gctgtagttc
   116761 ttcatttctt ttcaaaaagt cttctataac caagatattc gtctcagtta aaatcggatc
   116821 gacaactaaa agcggcttat ttcgataatt caattgaaag gtgctgaaaa ccagattgac
   116881 atccaattta tctactaatt cgatttcttt tgaacttaaa actgcagtaa tctcgatctg
   116941 aggaaacttt tctttcagat tctctgctaa cagatttcca gtagccatcc catggttaca
   117001 gacaacgact gatttataaa cataattcaa gtctcgcttg attacactgg cgatcgtcga
   117061 aaagtggatg acaagaaaag ctatctcgtc ctccagtatc ttgccaccaa ttacttcttc
   117121 gatcgtagga acaaaatgag tgactgcgcg gtagattggg aaataatttg ttcggatgtt
   117181 ttctttcaat ggattcatga cttggatatg attcttgatt cttacaatca gtgcagccat
   117241 gtgcttatag agattttcga ataaagcttc ttcctttaga tggaaaggta cgtgtgtctc
   117301 gttctctaca aattggatca attggatcgt tagtaattga gcttgtaccc actcgattga
   117361 attggagata tctctagcat tgaacgtctc aatagtgaaa cgaagataat ttctttctac
   117421 ttgcgggaca ttgtccaatt gaaattcctc gatcatgtgg tcaataaatg cagaaaagct
   117481 actgtctttt atttctgtat ttttccaatt aatggcagag ataaattcat gtttcctgat
   117541 tcgctggatc cagatcaatg taaaaagcag gatttgtttt ttataaatat catcttcttg
   117601 tttcaacaac ttattggaat agatctcctg tatttttttg atttccacca aaggaaaata
   117661 atggagaaag attttttgag ccggtgttaa ttgtgcatct tgattcataa agaagtcggt
   117721 cattcccaga ttctgattga taaaatcata gatcatcgta cggatagatc gttctgaacc
   117781 tttataaacc agtccttgct ttccataact gacgatctct atcccataac tgaccagtgt
   117841 tgctcgtaac cgtctcatat cttcatctaa tgtactttta gagatttgaa attcttcttc
   117901 ttttttgttt agatggatcg ggattcggct gtaagcaacg gctaaaacta gatcaaaaat
   117961 acgttcgcgc cgattcaaaa agccgtcttt cacatctttt atttcagttt ctaatcgagc
   118021 ttgcttttcc ttttccagct tcaacaaaaa acctttgttg cgaattgtac ggatctccgg
   118081 aagcttttta ctgctcaacc agatattcgc ttcaagaact tcctgacgga tcgtccgctg
   118141 actgacattg aactcacttg ctagatgttt tgcttttact ggatattggg ctgtcatgat
   118201 tctgtgaagt atttcaattg ttcttgtttt catagaaatg atctccttct gatttcaagt
   118261 atatggttcc gcttacataa taaaaagtag atatttctgc cacttgaagt ggaaagaaag
   118321 taagcaaagc aaacaaaaaa taagccatat gctttttcat ctcctcaacg aaaaagacat
   118381 acgcctatta ttacaaaaat tttgcccatc tatacaaaaa agaggttgtg aaaaagctgt
   118441 cctgcatcaa gtaataagaa caactaaact aaaatagtgc ttcctatttt tcgtttggtt
   118501 gttcttatta tcgcagatgc aagcttttaa acaccattta gtggagaggt tgtgacagag
   118561 atgttcagcc ttgagcgata agaagcgatt ttgaaaaatc gcttcccata ttttacaaaa
   118621 tcgtgcctta ttgccgatag gctatctctg gcacaccgtt tattcagaaa aaggagctgc
   118681 gacaaggctt ttgtcacaac tccgttcata aatatttcct gtcaatccag cataatcggc
   118741 tgaataaaat cggcttgcca tcttttttct ttctcagaaa aatcaaaata ccatatctga
   118801 gaaaaatact gtcgttgtgt cttacttcct gagatcaatc gcccatcttt tcgatcgact
   118861 gaataatcac agcatctgaa atcaattcgg atggcaaaac tattttcgtg gatctgtcga
   118921 taatttccta cttcctgaat agttattttt ttagtatgat ttcttacacc gtctgctttg
   118981 tttttttgca gaactttctg atgttcggca aacagcttgt ctgtataaca gcttctggct
   119041 ttttcaggag tttcttcttc ccaagcggat tggatcttca tgaatatctt ttggatttcc
   119101 agaaactgtg ctttcttttc tttagccgtt cctgacatgc gggacaatat ctccgctttc
   119161 agccttttct tttgtctttt attcttgacg atagaaaaag cagaaacccc tcctactgac
   119221 aaaacagcta atgcaagaaa tcccgtttgc tcataactag aaggacctgt acctggacca
   119281 taatacccat aagaatctct gccgtaagaa cgactgccaa aataactgcc cccatatgaa
   119341 cgaccaccaa atgaacctct gcccgaactt cgaccgctag atgtacctcc accatgacca
   119401 cccgcgacag cgaatccttg ggtcggcaga gcaaacaaac ataggcccac taacaaaatg
   119461 attgctaaat aattgatttt tttcattgtc ttcctcgtta tcttttatta caaaaaacta
   119521 tttttatgat agccttgcta aaaggaagag tcaataacca gatgcataaa ctgttttttt
   119581 agcaattttg tcttatttag tcattgagta acatcggaca aatgtatgtg tcggcagtcc
   119641 ataattcctc tatcttcagc atgaacaagc ttgcagacaa gagatctgcg cttcctccag
   119701 gagagatttg gttttcctga caaaagtgca acagtgctgt aaatggacga tttggtaaag
   119761 cactttgact agcagcatga gcaagttttt gcatttccac taacgttttc tgatcactgc
   119821 gatgcaatac gcatgtgtca tctagcgaac tcatcaaaac taacaacata tgcatttgtt
   119881 tctgtacata tgaatcatta tctagctcct tagctgcttg aattgcaagc ctgatatgcg
   119941 gataccctaa tatcgcttct tcatatgcac catttacgcc atatttttgc ttcaccctat
   120001 gaccatgagt ggttttttta tgacgatatt ttgtatcagg aaaagcagca agcttgctga
   120061 catcatcaag tattttcgat aaagaaaaag gctgttccat actgattttt tgtgcaatga
   120121 cactgatcaa tagccccatt gcccaaatcg ctcctttatg ggtattgatg ccatttgtag
   120181 caatcagcat tgccttttcc gcttttcgcc caatctcagc aattctttct cttaactcct
   120241 gatcaatagc atgatgccat gctatttgag ccatttcttc aaaaaaagga gttagcgtct
   120301 tagcagactt aagaaataaa gcatagtcca tatcggaatg tgcacccgca tccagtgcat
   120361 ccactaatcc aggttttgga cttaatgtta cttctgcgat caatgcttcc tctaccaacg
   120421 cagcgagttg ctgagtcact gctttttttc gttcgtcatt tatcatgaca ctcactcctt
   120481 cttcctacta ttacttgctg aaaccttttt tgatagctac ccaaatgata tgaagtaacc
   120541 agcttaaagc aaatgcacaa cttgccgtca ttagataagc tacaagaatc atgactcctg
   120601 aaggtaactg cagccaacta tctttaaaca ataataacag tacttggaaa acaaatacat
   120661 tggctaaata cgtacgataa gcataaacag acaaccattt gaacaatggc aattttggcg
   120721 aatcgtttac aatcattttg gaagcgccta tgaagacagc aaagatgatg actaaactgt
   120781 ataaactttg gatcgtattc aagtaaggtg cattcgcaaa gctcaagtct cctggatgtg
   120841 cgagcaatga acggacagaa aagaacgcga taactaaggc aacaggtaag aaaagataac
   120901 gtactctgtc caaatattga tagacttttt cgtgataaac aaatgcggct accccataaa
   120961 tcatgaaact agcaacaaac cgatctaata agtaccagct gtcatgataa ggcccagtca
   121021 atacttgtgt ttgatagaac agataccatg cgacatataa aatcgttgaa ccaatcaata
   121081 ctggccatac atatttttta ttagcaaata ctttgtaacc gagccaaaca aaaaacggca
   121141 tgaacaattg gatctgcagc atcataacgg tataccataa atgaggcgct ccatcacctg
   121201 tgacatattt cagtaaaaag cttgcagtat ccgtatacgg agtttgttgt tggactgctg
   121261 gaaatagcca aagataagcc gtcgtccata gaagatacgg aacgactagt tcaaaaaact
   121321 tttctttcaa aaattcccaa taagacaaat gctgacttgt ttttaccata ttataaacaa
   121381 ttgcaaaaat aaacattggt gctgtgtatt taacgatgac gtaaaaggta ccaagaaaag
   121441 ctgtatttgt tgcgctgtgg ctgtttgcca aagcaaagct caatatcgtt tgcatcataa
   121501 cagccgttac agctgatact ttctggaagt cacttacgtt gattttgatt tttttgtttt
   121561 caaacatctc tttctctctc tttttcttta ttaccaaagt tctttggtta atttaggtcc
   121621 ttcgactgtt ttcaatagaa tttttttctc tggctctctc aaatactctt ttagtgaaaa
   121681 accgccttgc cgagtcacta cttgggtatc gaattgctca aaaaaagcag gatgcgattg
   121741 aattacctga attggcaatt caatcggtga atttgcgtac agcagcaaat caaaatcact
   121801 ggtttctttt actgccggaa tcccagtcga taattcaaat cctaagctgc cgccgattcc
   121861 ccatttacat cctgataata tgtttctagc agcatgaaat tgctgataaa caggataatc
   121921 catgattttc tcttgtctat acgattcttg ttcgatgatg tcccacggat gaatgacttg
   121981 tttgacggca tgttttgaga tttctgttga ccatctctga ttgcgggcag gtccacgtaa
   122041 accaatcggt agtatttctg cgtgatccgt cgacgcacga cgaactgttc cgaacatctt
   122101 ttcagttaga acgacccatt caggcaaggt gaacccttct atttcatgtt tatcaaaaag
   122161 gacaatatca tgtgcttgaa tcatttttta tgcatcccat tcttcgtcca ttttggcacg
   122221 gactttattt gtttcgacac gtccgaatgt tttggctgtt tcgtttgtgt atcgatttgt
   122281 cagcatcgtg tcatttgtat tgcggacatc ttgaatggct tcattgattg cttcgatgac
   122341 tttgctgaca ttttgttctg aagcagcttg gtcggtgata tcttctagga aatgatagat
   122401 cgctcctagt tttgtataat tattgatatc gtaagcgata gctggaactt tttcagcagc
   122461 tgcttcgatt tcagcaaccg aacgttttgt cacacgtgca gcactttctt tagacatcgc
   122521 ttggacggta atttctttat tgtttaaagc aatcaagcgg cttgattgta atccatgtgc
   122581 taaaaatgca cctgaaatag catttcctgc aatcaatcca ataactggat gtccagcttg
   122641 acggagtttt gcataagcag cagcactatt agccaaagcc acatggatac cgatcaattc
   122701 ttcgttatag ccgtatgctt ggcttggtac atcgatcaca acgatgattg gccgtttcac
   122761 ttttttgtct ttatcttctt cgtaaacgtg atccaaaatt tgtcccatgc ggaaaccttc
   122821 aactaaacca acttcaccgt ttcgtacacg gtacatcggg tttttaggat caggtacgat
   122881 tgatgtcacg atggcttctt ctatgaattt acttgattta ccataataca cagtactaat
   122941 agaagaagtt ggatttttca tgccagttag tgccgcaaac caatcgtaac caacacttgc
   123001 tgcagctggt tcatttcctt ctgctacttc tggtaagtca attgattttg cttgatggtt
   123061 agcaattgct tcattgtaat cgtcaatggc cattggtttt gaaagatcta aagaatcaag
   123121 taatgataaa taaaatgctg agctttcact gcgatgcgtg tcttttcgtt cgtccattgc
   123181 tgcgatgaca gcagctttga ttgcttctac actatcagtc actaattcat caatgatttt
   123241 tgattctacc cgttgacgag atcctaatgt attccaaatc aagtctttgt cactagaatc
   123301 aaattctcga acgcctgctt cttgttcaat aacttctggt ccattcaaac cgactctcgc
   123361 tttttttgtt gcgattaaat aactcattaa tgctgaagta atcgacatac cgccaaatga
   123421 tcctacacgt cctggaatca aaccgatgac tggtacatat tgttttagag caatgattac
   123481 atttccgatt tctgaaatag ataacagtcc gtagtttgct tcttgcaaac gaacaccacc
   123541 tgtatctagt acaatgactg gaaagatctc atttcctttt ttattttctt ctaacacatg
   123601 ttcaagtgca gcaacgattt ttgcaccgga aacttcaccg ataccgccac cttggaattt
   123661 tccttccata gcgattacta ctgcttgttt gccattgatc gtgccacggc tgacaacgat
   123721 cccgtcatca ctttcaggga cgattccttg tgctggtaaa cttggcgcga tgatttgatc
   123781 gaatggatca atcaattcac gtccattgtc aagtagagcg ttcactcgtt ctctggcgtt
   123841 taattctaca aaactatttt tcatctgaaa gttcctccat tgcttgcgtc aatcgtaggt
   123901 acacaactcc tggtgtagca ccgaagtcat tgatcacgat atctgctgaa attggataac
   123961 gatcaaaaaa tctcgttaat acattgttcc atacttcgcc gaagccatcg cttcctgtac
   124021 aaatttttac agtagattct gttttttctg ttggaaacat caagatttcc aaatctcctg
   124081 aaccgaccac tcctacatgg attttcttat tgatcggctg tttcgttgga tatttataag
   124141 ctaattgttc catggatctc tccccttttt gtaaaacaga gcatacacgt tctgcttatt
   124201 cgtctttctt cttccatctg ggtaaatggc gacaaaaggt ttttctcgcc aattttatga
   124261 ccaagttctg aatttcattg gtggttcata caggccatct gaccattcga tcaaatcatc
   124321 gatggtttgt gcagctaata atgaacgttt cgcttcacta cgtttgatgc ctagatcttc
   124381 tggtaatttc acgatgccgg ctgcacgcaa gctatctagt gattctttcg tgctagtcat
   124441 tccaagaggt gtaacaccgc caattgctgc aattgctgct tgtcgttctt cttttgtttt
   124501 tgctttgtac aaataagcaa ttccttcttc tgtcacgata tgtgtagtat cttcgctata
   124561 aatcatcact ggtgcattgg ctaagcctgc ttgtttttga acagctagtg catctaattc
   124621 ttcgacaaag actggttttt tatttgaacc atatgtttca accatttgaa caactaattt
   124681 ttggcctttc cctaatggat catcattgtc gcgaagtgat tgccatgctg gtgtagaatg
   124741 acgacgaccg ccaggattat gtcccatgtt aggcgcaccg ccaaaaccag ataaacgtcc
   124801 ttttgttacg gtagaagagt ttccttcgta atctaattgc aaggttgaac cgataaacat
   124861 atcgatggca tattgtcctg cagcttgtga taatgttcgg ttactgcgca tcgtgccgtc
   124921 tttaccgaca aaaaagacat ctgggcgagc agcaatatat ttttccatac caacttcgcc
   124981 accaaaacta tggatgcttt caacccaacc tgattcgatg gctggaatca tcgttggatg
   125041 tgggttcaat acccagttct tcgcgatttt cccttttaac cctagtgatt caccataagt
   125101 tggcagtaac aattcgatag ctgctgtatt gaatccaata ccgtgattca aagattgtac
   125161 gccgtgttct gcgtagattc ctttgattgc catcattgcc attagaattt gcaattctgt
   125221 gatgttttga ggatctcgtg tgaataaagc ttctaattga taaggtttat ctgctttcac
   125281 gacaacgtct acccagtcac cagggatatc tacacgtggt aaagaatcga caacttcgtt
   125341 gacttgaacg atcacgatac catctttgaa agctgcagct tcgatgattg ttggtgtttc
   125401 ttccgtattg aaacctgtgt acaagttgcc gtctttatct gctttatctg cagctactaa
   125461 aacaacattt ggaatcaaat cgatgaataa gcgtccataa agttccaaat aagtatggat
   125521 atcacctaat ttcattgtgc cgtcttcaat catttgggcg acacgcaagc tttgtgcacc
   125581 agcataagag aaatcgatct tgcttgcgat tcctttttca aaaatattca aatgttctgg
   125641 tcgtgagata ctagacatga tcaaatgcag atcattcact ttttctgcat ctactttttc
   125701 aagactttct gaaagaaaac ttgcttgttt ttgattgtcg ccttctaata caactttgtc
   125761 gccgggagca atcagttttt ccattacttc tacgattttt tcagtttcta catacttgcc
   125821 attgagcaag ttgctgattt tttccaatcg ctgcgctttt ttttcgcgtt tagaagccca
   125881 gttgcggttt ggtttttcca taattagtca tctccatttt tgatatagaa acgtggcgtc
   125941 atcaatacca tgttggtcta gattgatcgt acggatccct ttatctacac caaattttgt
   126001 atgaatcagc tttgtcaaag tattgccggg gggaaattca atcgtcagat ccattcctaa
   126061 ttcttttgcc aagtccatca tttggttcca ctgcacaggg aaagctaggt tttccaacaa
   126121 atctttacga atctcttctg cgtcctgagt ggctcttcca tccgtatttt ttatatacaa
   126181 acatctagca tcagatagat ggacagactg catatacggc ttgaatttct tgaccgtatc
   126241 attcatcaag agacagtgag atggcacagg gactttcagc agcttcgctg tttgcgcttg
   126301 gtgccgtttg gcttctgcca acgtaacgga taaaccttcg atactcccag ataacgtatg
   126361 ttgcatcgga caattttcat ttgacagata aactggatgg tcaggatcaa atgtttttgc
   126421 tacaatttcc tcagcttcgc ttctcgtcac acctactact acgcccattg cataaccgct
   126481 tggataagct tctttcatta agactgcgcg gtgatagact agttccgctg cattctcaaa
   126541 tctcaaagat cgacaagcaa cagctgcaca aaaagcacca atcgaatgtc ctgctgcaat
   126601 atcaggctga ataccgtttt tttccatttc atctaaataa aatactgctt ttgtcagtaa
   126661 tgctagctgg ataaaaaccg tatcttgata gttttcttct ttatcaacta accgataccc
   126721 cgtcacattt tctaaacgtt ccatgtacat ttcagggata tccgctaaca tccctaactt
   126781 ctgactgcct tgtccaggaa ataagaaacc tgtactcatg agcctcgcct cctcagcact
   126841 tactttttcc actgctatct tagtcaattt ctgctataat aaaaaatgcc aaaaaaagaa
   126901 aaaaccataa caaaaaggta tggatgggat ggataattat gaaattgctt catctgcagt
   126961 attttaaaaa agtattcgaa acaaaaaatg ttacccaagc agccaaagaa ttatttattt
   127021 ctcaacctgc cttgagccgt gcgatcaaac atttggaaaa cgaattaggt gtccctttgt
   127081 tttaccatag cggcagaaac attgagacga ccgtttatgc agaagaattt tatccatatg
   127141 cagtcaagac attagacaca ttagaagaag gaatcaaatt attgtcttcg gtcaatgaga
   127201 agatcgttac ttccgtcata ttgtatttag aggtagcctc tgtttctatt ccgaacttgg
   127261 tccgaatttt tatggaaaag catcctgata tccaattaac gatcatgcaa catcatttac
   127321 cagatgatat taccgatcct gtactgtaca tcacttcgga gatgaagcct ggcatgacca
   127381 atattcctat catgaaagaa cctgtttatg tcgccattcc taagaaacat cctcttgcta
   127441 aaaaagaaca tctgcaatta gaagatatcc aacgcacccc catcttgatg ctgtcaaaga
   127501 gcaacgcctt ccgtcataca ctggatgcag cacttgaagc gaaaagtatc gaattgacga
   127561 tcagttcgac gacagatgat cctgcgacat tacgttctat tgtcaagcaa ggattagctg
   127621 ttagcttttt cccaaaagtt tcttggtctt acgataaaaa tgatcctttc gtcttgcggg
   127681 aaatcaaaga tttgcccttg acacgaacaa tttatttatc ttctagcttc acagaagatc
   127741 atcctttgat caaaatgatt gcaaaaacga tgcgggaatt ttatttagga aaataaaaaa
   127801 aaaagagctg ggacaaaatt cttgtcgcag ctcttttttc gaacaaacgg tgttccagaa
   127861 gtaatttctt agaaaataag ccgaaatttc ccaaaaattt gagaagcaat tttcgtaaat
   127921 tccttcttat ttcttgaagc taaacatttc tgtcacaacc tcttctctat tgtcctagac
   127981 attcattgcg ttgatttaaa acttccatca atcaaatctg ctagttcatc tagcttttct
   128041 attttacgta gatcaataga gatccaatgt tctttattca tgtgataggc tggaaaatac
   128101 ccctcttttc ctcgcaaaat tccgccaagt tcaggatcga ccttcaaatc aagaatattg
   128161 atgatcctat ggtcacttgc atcatcatag attttttctt ctggaacaga catcaggacc
   128221 ccaaaccatt ttttgctttt ttgatgtctg aatacgcaat aatcaggaaa ttttttaaaa
   128281 atatattctg gagacaaatt gtatgtttca ttgatgtgat cgattagttc ttttttcgtt
   128341 agcatctgct tccatctctt tcttattgat tcgctttatt caaagatacc acgtaagaat
   128401 agaaaaatga atacaagtag ttgctaatca aatacttcga tatttttctt ttttatcaac
   128461 tcttaaatgt tcaatccgcc tgtgttggtc ttgctaccat ctactattaa aatgtttatt
   128521 attgtttgcc cacctatttt ttgattttag tggtatcatt tttcaagttc atgatgaaat
   128581 tcttatcatc agtaaatgct ccagaaaaat aaacaatgat tgaaaaatca gttgaaactt
   128641 gaccaccgtt tattttctcc gtattcttag aatagaaggg agtctgattg atgtattcac
   128701 taatgaaaaa aatcattacc gaaaaagata ttcgacgtca tgtttcttta gtagaacaat
   128761 tgctgaatca tacaaagata accgtaaatg aattagctga aatcataggg acaaccgaac
   128821 gaacgatttt ttctgacctt caatctattc gctctcagct gcccgaaggc tgggacatca
   128881 tcagcgatca agcaggaatc agtttgcaaa accagcaaaa tttattaaca aatgaccttt
   128941 gggagatttt tttcaaacaa tcagtcagtg tcgaactgct gaaaaatctg ctttttacaa
   129001 aaaaagttgc tgtccctgat tttctagccg accatgggct ttcttatggg acattgaaaa
   129061 gacatgtgac taaaatcaat cagcgtttag caagttacga cttgcagatc gatttgacga
   129121 aatatacagc ttgtattctt ggaaaagagc gtgcgattcg tactttttat catcgattgc
   129181 tgattccttt cactcataac aactattttt tcgaggatta ttcgatccat gaatcccatt
   129241 attttcaatt tttaagaaac ctcagtcaaa ctgaactagc ggttgaaaca gaagagattt
   129301 tcggaacatg ttggttcttt atcaatacga tccgtataaa agcgaattgc cgattagatt
   129361 cttctatcca taccaacagc acactctcct ccctgtatga ctctgcattg aaaaaattgt
   129421 atttaacgga aggtatttat cttaaagaca ctgagctttc ttttgcttct ttctgctttc
   129481 tggaaagttg gaattacaac aataactatg gacaagaaac cgctcgctgc ctgcatcatt
   129541 ctccattttt agaggtcctc gaaacgtttg tagaggaact agcttcagag ctgtctcttg
   129601 atcaactaaa aaaaacatct ctgactgata acttggctct cctcatatta aaatatcatg
   129661 aatcgccgat attgattgaa gcattggacc gtcaatacca tcgtttttta gaaacatatg
   129721 atcagcaata tgcacacttg tatcaacaga aagagaattt actgaacgat ctaaaaaaag
   129781 aaatagaaat caatgaacca aattactttc tccaactctt gtctctactg atccaacaaa
   129841 cgattttttc tatcaaaccg aatttgttca atgtctattt tattttccaa ggagaacctt
   129901 catggaaggc gttcttgcag caggaattaa aagattactt aggaaaacgt gtctgcttct
   129961 tacctatcga actaaccgat ctttccacta tttcttttga aaaaacagat atcttgattt
   130021 ccaatttccc tctagattct ctagatatcc ctattgtata catttcttct attccaacga
   130081 aaaatgagct caatcgtttg actgaactca ctttcaaaac ttttttatag taacggctag
   130141 cgactgtatt ctctagctgt tttttctttt ttgcgaaaca gtttgttcat gatccctttt
   130201 tctatttcta caactaagaa tagaagaatc acatttgctc caatcaataa ctgttgtgtc
   130261 atcgttaaac ttactgtacc gatcagctgc tggccgactg gtagaaaaat aaccatccct
   130321 tgcaataaag caaggatacc taatgaaaga aaaagcgctt tgttttgcaa aagaccttgg
   130381 ttcaatgacg gcttggacaa ctctctgcaa ttgatcatgt aaacagcttg agctaagacg
   130441 atattttgca gaagaatggt ttgctgtaag ctttgccctt caaactgcat agccaataaa
   130501 taggcaggaa ccatgatcag tagggagaca tagatgatcc gaaacaaatg ataaccagat
   130561 aggattcctt gctttggatc tcttggtggg cgcttcatga tttctggatc tggcgactcg
   130621 aaccctagtg cataagataa agtgattgtc gttaccatat tgacccataa aatctgtact
   130681 ggggacaaag gtagcgggcg attcagcata agtgcccaaa tcaagatcaa tccttgagct
   130741 aatgcagttg gcaagaagaa attgatggtt ttttgcaaat tatccaaaat ccgccggccc
   130801 tcttttacgg cttttgcaat cgtatggaaa ttatcatctc ctaaaaccat atcagctgcc
   130861 tgtttgctta cttcactacc tttgattccc atagcaattc ctacatcgga tcttttcaaa
   130921 gcaggtgcat catttacgcc gtctccggtc attccgacga tttctccatt tttctgcaaa
   130981 gctttaacaa ttcgcagttt atgttctggt gtcgttcgag caaagacatc gactattggc
   131041 acttgctgaa tcaactcttc atcagacata agatccaaat cgatcccttc taaaactttg
   131101 gcagtatgtt ttaagccaat ttgttccgca atcgcttttg ctgtgtcttt gtgatcccct
   131161 gtaatcattt tcactgagat ccctgcttgt tggcattcct ttacagcttt gactgcactt
   131221 tcttttggcg gatcgatcaa tccggcgatc cctgcaaaag ttaattgggt taaagtctca
   131281 tgcgtgagtt cctgtttcga atctactttt ttataagcaa atcctaaaac acgctgacct
   131341 tttctcgcaa attctgcagc tgtctgactc catgcttctt gttctgcaga agaaagagtt
   131401 gatttagcaa ataatacttc tggtgcacct ttgacgtaaa tcaccgctcc tttttcctcc
   131461 gcatgcatcg ttgccatata tttgtattca gaactgaacg gaatctttgc ttctattttt
   131521 ttcaaaggta gattggctgt ttctgtgtgt cgaatcagcg caacttctgt cggattgcca
   131581 cttaaatttt ctgttttctg ttcttctttt gtttttaatt cctgacagtt tttcataatg
   131641 gacaacacgc aggcttcttc ttttgcagct acatccacaa ctgtcatttc attttttgtc
   131701 aatgttcctg tcttatctga acagatcact gtcatagaac ctaatgtttc taccgaagga
   131761 agtcctttga tgatcgcctt ttcttttgcc atttcatgta ctccaacgga tagaatcatg
   131821 gtcaaaacag ctggcaatcc ttcgggtacc attgacacca ccaaagcaat cgtagccgaa
   131881 agaaggatat gccaatccat accatatcga aatgtcgtaa aaataactaa gaataggctc
   131941 aaacaaagaa tgccttgaaa aatttgtttg tttaatcggt tgattttttt aatcagaggc
   132001 gtcgtttgtt gttcgaccga ttgcaatgct tgattgattt taccgatttc tgtcgtgttt
   132061 cctgtttcta caacgacacc gactgcagaa ccagattgta caagcgttcc tgaaaaaccc
   132121 atatttttct ggtcgccgat cgattcttct tctgtcaaaa cggcatgact tttttcagat
   132181 gcttctgatt ctcccgtcaa aatcgattct tccactaata aatcatgtgc ttcgattaat
   132241 cggatatctg ctggaacgac atctccggca cgtaagacaa tgacatctcc ttttaccagt
   132301 tctttcgcag ggattttttc ttgcatcccg tttgatagta ctatcgcttc ttgtcccatc
   132361 agctgcttca aaccattcaa tgattcttcc gcttttcttt cttgccagta actaacgagt
   132421 ccattgacga tcactacgaa taaaataata cttccttcaa tatattcact agaagcaaat
   132481 ttcaaaaaag aggcaatgat caacacgatc atcagcagat cagtaaaatg ctttgctatt
   132541 tttttccatc gttttgtctg ctgccttgct tttatttcat tatatccttg atcagtcagg
   132601 cgtttctgtc gttcttcttg cgacaagcct tctgttgatg tttgatagtt tttcaataca
   132661 tcttctaccg tcaatctgta ccagttcatc ctatcccctc ctgtttaatt gatactgtta
   132721 ttatacgcag ggaagttttt tcaggcgtat cgattatttc aggggggtct gaaataattc
   132781 gttttgcaaa atgtatctgg gcctaactga tatttctatt gcttattctt ttatatacaa
   132841 aatttaagaa tacaaaccag ataaccaata aaaaaggaat aaagcgtgtc gtgctttcga
   132901 ataacaagct gaaagcaatt gaagtaaaaa acaccaacaa agcaagatct ttatatcttt
   132961 gtgtagtgtt ccgtttcttt tctttaataa attgaacatg tgcacacaag atcgaagacc
   133021 acacaaatag aaaacaactc gttgtcatgc ctgccaaaag ctgaaaaaac aatcgactat
   133081 cagctacaaa aaaatgtaga caaagaccgg caaaaaataa cattcctgta attaaaatac
   133141 cgtgtaaagg tacgcctttc ttagaaagcg cacaaaacca atggggcaaa cttttttctt
   133201 ttgctgtttg atataaaatc ctgctagtac tgtagactgc actatttgct gaggacaaag
   133261 aagcaaccaa aatcattaga ttgacaattg ctgctccgcc ttggcaatgg atcacttgca
   133321 gcatagtcac taaaggactt tcttttaaat ctaaacaatg ccatggaaca acaaataaaa
   133381 tcgacaaaat cgttcctata tagaaaaaga gaatacgcca aggcagacag ttgattgctt
   133441 ttttcaaatt cttttgcgga tcacttgtct cgccaacggt taagccgatc atttcaattc
   133501 cagcaaaact gaataaaacc ataggaaatg agactaccat tccagcaaag ccaaacggta
   133561 gtaattcatc gatctgtcca aaattttctt tgattccgat agactgggta tgaaaatctg
   133621 agacactcaa tcctataccc aataagataa aaaggaaaat ccccaagatc ttgatgattg
   133681 agaaaaaaga ttccaattca ccaaaccact tgactgcaac aaggttgact gccattaaga
   133741 tcattagtgc gctacctccg cttatcaaag ctggtacatg tacaaaccag aaatggatat
   133801 acaatcctat tgctgttaat tccgcaagtc cagctccaag ccagcaaagc caataagtcc
   133861 aattgacaaa aaatgcccac tttttgccta aataatagtc aacgaaatca ctgatagagt
   133921 taaatgtact atttgctaaa aataaatcac ccatggcccg catcaaacca taaatagcca
   133981 aaccgcatat caaataaacg agaataacag ctggccctgc tgatgcaatt gcctttgctg
   134041 aacctaaaaa taatcctgtt ccaattgcgc cacctaatgc gattaactgg atatttcgat
   134101 tagttagagt ccgtttcatt gccggttttt ccatcaagtt cacctttttc tttttcaagc
   134161 agcatggcga cttcctgttc ccaagaaggt ttctttattt tttcaataca gagtggtact
   134221 acaaacaaaa tgacactgat ggctgtgact gcaattagat tgatccatgt tccagctttc
   134281 atcgtcagtc cgacagaaaa tccgattgcc gcaaataaaa caataacgac agtccaaact
   134341 ccaagattgc tctttttctc tttttttcca attctaaatg gtcgattcaa ctttgcatgt
   134401 gtataacgca atctcaaaac tgcgatcccc atgatgacat agacgataca gtagataaca
   134461 gtagttgaat ttacgagcat caaaaatgct tgattgacgc caggaatcag caaataaaaa
   134521 agtgcaaaga ttgagataat gacagactga gtcaaaataa cggatttgga tacgtcaaat
   134581 tgattcgtct tccaaaaatt gaattttggt ggatacgcac cttttctagc actttctgtc
   134641 actgtctttg ctggtcctga ggcccaagca gataattgga ctgctacacc aatgaagaca
   134701 agtaaactaa acagattcac aataagatgt ggcaaaccaa gaatttggca ataaatcgaa
   134761 atagattgcg cgatattatt caattccatt tgtccttttg gtacgacatt tgctacaact
   134821 aaagcattca aaatattgac gaaaaatata aaaattaacg cggcaaatac tccgcgaata
   134881 tacgttttaa ctggattttc caatcgagtg atatacacag aggacatttc gataccagta
   134941 aaaataaaca tgatcggcgc aaaataaaca aatgaggatg cagtcgtagt atctggtatt
   135001 aatttgtccc atgaaaaact gcctaatgtt ccggttggta cgatcccaac tttgatccac
   135061 gcagcaaacc ctaataagag catcatcgtc aaaggcacgt acaatcctaa ccaaacaccg
   135121 acttttccgc cgatttttgc catatcaaat ttcaaattca aaaaagtgat gatccaataa
   135181 acgactaaaa tgacaactaa tgtaaatttg ctgttcaaac caagcggcac attatcgata
   135241 atattaccaa acaacggagc gagtgctgaa gcgaccatca ccatcccagg aaacatttgg
   135301 acccataaca gccatgagac aacgaacccc catttttttc ctagagcatt cgatacccaa
   135361 agttctggac cacctttttg gggaaacatt ccagcaaatt caccagagat caatgagatt
   135421 ggaaaagcgt acaataatac tgcaaccagc atgtaaaaaa tcatcgtcca gctcgttgct
   135481 gctacatctg gaatatttcg tacacttgct acaagggcgc aggtcattcc gataaaggtc
   135541 atggtcgtga tttgctttga tgaaccagta tctttcatct ttattccttc tttcaatagc
   135601 gacatatgtt tttgttttct tttatttttg ttcaagaaca gaaatgacaa ggtttcatcg
   135661 attcagtaca aaacccagta tcaccgaaac atccattgaa cgatcttagt gaactgggtt
   135721 tgatacatga aacgaacgat ccaacttata gaacgtttta taaaaaagaa tatcttggcg
   135781 aggaatatat gaaaaacagg gggaaataca attgttttga tgaagcaaat aattgtctgt
   135841 tctccatatg tctcttgtta ttctttcaca caaaaatcag ttctattgga tgatttcgtt
   135901 tagtttcttt tccattgctt tggcgatttt ttttgtataa aaattgaaaa ttcgatcatc
   135961 attcaaataa ggagtcatga tagccgcacg tagcagagtg attttctgtt cttttttcca
   136021 ttcttctttc gttagaccca ttctttcaac aaaacgaatc ggagaatcac cgtaatcttc
   136081 ttgtgtaaat gtagtatgag aagtaataaa ccgttcacca taaacatcgc catccatata
   136141 agaagaccga tcgaacattt tttcatttaa ttcattgata gcgttcaaat ctgtacagcc
   136201 ttgttctttg aatacccaat tgaccatatt aaaatcagga tgattcaatg gatagacttc
   136261 gattgttttt cctttaacag taaaagtcag atgatcgaga aattctctga atctttgagc
   136321 tgcctcgatt gaagccccaa tcaattgacc atatccggtc acattcaatg gcaatacacg
   136381 atgtgctgtc cagactgcgg cggcggttgc tccagctttt gatccttcca aaatataagc
   136441 tcctaacata tctggagcct ttactgattt ttcaaacaca tatggcgcga aataagaaat
   136501 gatatttctc atatttttat gtttgattac gattcctcca gcagcataag ggacatagcc
   136561 catcttatga ggatctatcg tgacagaatc cgcttctgaa atagctctga acccttcata
   136621 tacctctttg tcaatcgtta cgcagtggtg gaaaacatga tgttcttcaa agaattcagc
   136681 taaggaagca tacggcacaa attctcctgc ttcgtttaga aacagtgaac gcgcatagcc
   136741 gccatatgcg gcatcaacat gtaaatagaa atagatccct tcatctttta acctttctct
   136801 taattggacg attttatcta cactgtctac ttgaccttct tctgtcgttc ctacgacagc
   136861 aaccacacct agaattggga ttttttgtcc agctaattca cgaattgttt tttccaaagc
   136921 attaatatcc attcgataat cctcttgaac tgggatagca accatctgat ctaagccgac
   136981 tccgcaaata tctaacgcct tcatccaaga atagtgtttt gtttgaggga ccagccattt
   137041 ccctaatctt tggatatttt ttccgctacg ggaagaagct gctttgacct catccatttc
   137101 ttcgtccgta aagctttcgg tcatttccaa aatttcttca acagataaat tcaaaagttc
   137161 ccactcagac atttttttca ctttttcagg cagcacttcc ttgacagcta aaggaatcga
   137221 tttgatgcaa cgggcgtacc ataatccttc aagattagca atagaaccat ctgctgcaat
   137281 gtgtccccat ccgtctgtca tattgaataa tgaagcaaaa tcctgtccta cttctgcttc
   137341 catttgcgaa gttgccatag aagattccaa tgcaacatta tttgggttcc acagcatcgc
   137401 atagttgtaa gctaataaag caggcatcaa tgtttcagca ttcatttgtc cccagtaacg
   137461 gcctgctgaa tgccatggga tcgatcctgc gcgtaatcgc tgactgactt catccaagac
   137521 ctctatcata tggtcgcggg tggctagata atctggagtg agcttatctc cttcgctaat
   137581 tgcaggcata tctgaaggaa tataattttc tctccatcca agatgttcat ctaccatctt
   137641 gttcaacaac attttataaa ctggtccatt ttcagctttg tcgcctataa agacggcctt
   137701 gatatccata tctttcattt ttcttccctc catattttgt tggtcaatgt cttgcagata
   137761 catgtgttta tctgtaacac ctcttcacta tagcgccaaa aatgagaatt ttttttttat
   137821 aacatcaaat ccacgtagat ttttacaaac aaaaataaat aaagtcggat ttttctgata
   137881 attcaacgca aaaaagcgaa caatttttca ataaatcagt cttctaaaat agataaccta
   137941 aaaaaagcga acaaacaaat aaaatgactg tccttcattc actaaacata tttttatttt
   138001 tttatattgt taaaaattcg caatttattt tttaatagaa ttatctgttt tccaaatttt
   138061 ataacataaa aaaccttttt taacggcatt tatatgcttt ttcagaaatt aactgatgat
   138121 ttcaaaaaga aaacatgtca taatatttcc catattgtgc aaaaaaatac aaggcggagg
   138181 ctctactatg attgaagaat atattgagaa aaatatttta agacagctgt ttttatgtgg
   138241 gcaattctat gtaaataaag aagtcaatct agaaaagctc tccaatctcc tgcatgtttg
   138301 caaaaccact ttactcaatg atatcaataa cataaaaaaa gaatttgaag aacagatcgc
   138361 ttatacacat cgggaaaagg accgttacac tttatatttt tcagaacata tacctcgatg
   138421 caagatcatg cagcaattgt ctcaaaattc gttgttttta aaaacttgtc tgctttattt
   138481 ggaagaagat gaacctgatt atcttcaatt aactgaatgt gaattcatct ctgtcagcaa
   138541 agcttattca ttaaaaaaac aagtattagc ttattttaat gactgcggga tcgaaatcga
   138601 ccgctactcc cctcgattca ctgaaatgga aagacgtctg ctgcttctta atgtgtcgta
   138661 tcgtttaggc ggttttaatt cttgggagct acctgaatcg ttttttgaac gtgccgatcg
   138721 tttcattgaa tccgtaacgg aaaatagtgg cagattttat gataaagaaa ataaagaaat
   138781 cttatcgatt ggttttgcta tcagtttcct acgccagcaa gtgtgtgctg tgacaataga
   138841 ttcaaaattt atcgaagaaa tcaaaaaacg tcctatttac aattatgtcg aatcagcatg
   138901 ggaaaacact gatttccaaa cctattataa aaaagaagaa ttcgccttta ttttgacact
   138961 attcaatctt tgtaattatg gtttccattc ttatcagttg attgcggaag actttcaaca
   139021 gctacaccaa gtgtttattg acaatactcc cgaaataaaa gaactagttg ctacctttga
   139081 atctcacttc aatcaagaat tattcggaaa ccaaccgttc gaacgtgcgc tgattcatct
   139141 gatgcgttcg gcttgggata actatcaatt attcatgcca gaaaaatttt atcttttaaa
   139201 tgaggaacag acaaatttat ataaagaagt ccagacaatt ttttccagct ggtccagcca
   139261 gttaccttat gatctacggt tgaatcctaa ttgcatgcgg gcttttgtga tcgaattgag
   139321 cggaattctc cgtctgacaa aagaacatct gactatctat atcgtcacaa attcggatgt
   139381 tcattatctg atttatcggg aagccttgga agctgtaact actttcgatt ttcaagttgc
   139441 accaacaatt tattcaagta tatctgatat aaagaagtat gcgcagcagt cctcaaaccg
   139501 ggtattatgt gaacgtacat tatatacacc agatgcggtc caatatgaaa atattattcc
   139561 tatttcgatc aatacgatcg atcgagctat catttcagct gtgcaaaaca aataaggggc
   139621 tgtgacaaaa atcatgtcac agcctcttat ttgttgaaga tgcccatttc tgtaacaatc
   139681 tcttgataca cgtcaggctc acaacctcac ttattttgga catctacggg tccgatctct
   139741 ttatttaaaa aataagaaat gatggttcgg ataactacca acgccgctag ttggaaaata
   139801 tcctgcaagg taggtttgat aatcgattcg atgatcccag ctgaaacaag aatttccaaa
   139861 cttagaagta tatagcctcc caacatcttt ttaatagcat tgttctcgct gactcggtcg
   139921 ctttgcactt ttgtatggac aaataaatat ttcaaaaaat ccttgattga tagacaaaca
   139981 ccccaaacca ataaacagat agcaaagata tcaagtccca gtacaagttt ttcgaaatat
   140041 ggaagaagaa actgcatcaa ctctgtcgtc atcctacctc tcctcttctt tgtttttctt
   140101 tgtcttctat ttcctgattc aagaaataag aaatgactgt tcgaatgata ataataagtg
   140161 caagcttcaa aatatctgtc caagtcggct tgataactga ctcgatgata tcagcaacga
   140221 ctagtacttc caagcttaac aaaatataac ttgctagcag ttttcttgta tctgcattac
   140281 gagtattacg ttctgcatag tttttcttga catgagacca atcaaaaagt ttgaatagaa
   140341 caagaacgat cccgacaatt aagataccga tagaacaaat atttaaaata gcaatgatcc
   140401 attctagaaa ttcaattaaa tttgagcgaa acatatacgc tacctacttt cttttaattt
   140461 gttcctattc ttttattgta aaagaaagtt accttgttcg tctatttaaa agttgttcta
   140521 atgataacgg ttcgcttaaa tttttctttt tcactctccc atttttctcc ctccatccat
   140581 aaatcgtgga agtatccaaa acaacgtagc aagttaaaat aaggcttagt ccgtcatcag
   140641 cttttcaaag aagcactgtc tcggtgcttt ttttgtaccc aaatttctaa aaatagaacc
   140701 atacacctcc tcaaatcttt tcttcttacc taccctattt ttatttacag gaaaatcaga
   140761 cacttcttct tttttgtcaa aatttccttt ttcttctcgt cctatcattt ggcattctaa
   140821 taaaaacgaa ctatccttgg atatagaaag agaaaacaag gaggcgtttt tcatgagtaa
   140881 aaaattaatc aaagtcggca tcggtttagg tttgcttgcc cttggcgctg catatctagg
   140941 aaaaaagaca ggactattcg aagatgacag tcatttatat gatgaattcg aatcaatcta
   141001 gcatcctatt tagttgaatc actacggaca tacttggaag acattggagg aatcacaatg
   141061 agaaaaagta aagcaataat gattggtgcc ggtattgcca atatggcagc ggctgtttat
   141121 ttgattcaag aaggcaaatg gaaaggggat cagatcacct tttattcatt ggatgatcac
   141181 ggttcaaatg atggtgcacc gaccgacact gtagtggatt aatattggaa taaaaaccat
   141241 ccattagaaa accaaaaagg ctatattgct cgaggcggtc gcatgcttaa ttaccgtacc
   141301 tatgtagatt tgatggatct gttaagtcga ataccttctg ttactgagcc agggatgact
   141361 gctgaagaag atacgagaga ttttgatgca aaacaccgaa cctttgacaa agcacgtttg
   141421 atggaaggtg gcaaaggaat cattgatggc ggaaaactgg gattcaataa taaagaccgt
   141481 attcttctga ctaaactgat tgctatgcct gattcagaag aagaaaaact agacaatatc
   141541 actatcgaag aatatttcaa agatgatcca cacttttttg aaacaaactt ctggtttatg
   141601 tgggaaacaa catttgcttt cagaacacgt agttctgctc aagaattgcg tcgctatatg
   141661 catcaaatga tttatgaatt cactcaaatc gaacatctag tgggcgtcaa tcgaacacgt
   141721 tacaatcaat acgaaagtat tatgcttcct ttgatcgagt acttgaaaga acaaggatgc
   141781 aaaatcattt tgaaccgccg tgtcactgac tgggaattca aagaaacacc gatgcaagat
   141841 gaaatcactg tgactggttt gaaaattacc aatacactga ctcaagaaga agaatacgtt
   141901 gtggtcgatg aagatacagc agttattttc actaatgggt ccattacaga ttcagctact
   141961 ttaggagatt acgaaacacc agctgtagaa aatatggatt atggtgcagc ttctagtctc
   142021 tggaaaaaag ccagtgaacg tttctacaac ttgggaaatc ctgacaaatt ctttgctgat
   142081 cgagatgcaa gcgaatgggt cagctttacc ctgacgacga aaaaccattt gttgttgaat
   142141 gaaatcaccc gtatcacgac tcaagaacca ggaaatgcct tgaattcatt tatttcaacc
   142201 acaccgatca cgccgttagg ccaaaaagat gtcaatatgt ctatcgtcgt gcatcatcaa
   142261 ccgcatttta cgtctcagaa accaaatgaa acagttattt ggggttattt cctttatcca
   142321 agacgacgtg gcgaatttgt ggataaacag tatattaaaa tgaatggaaa agaaatgcta
   142381 gaagaactga ttggacaact ttcaaaagta gatcctggac cagtgaatat tcgtgaaaaa
   142441 gaaacagaaa ttttcgacag cgtaataaat aatatccctg tctatatgcc ttatgcttcc
   142501 gcgttgttca ataatcgtgc caaaagcgat cgaccaaaag tcattcctaa acattcgacc
   142561 aatctggcct ttacaggaga atttgtcgag cagccttatc agatgatctt tactgaacaa
   142621 agtgctgtac gttctggaga aatcgctgct ttccattttg cgggtattcc tatgtcccgt
   142681 cttgtcaaaa caccgcgtta cgacaaagat attcctactc tagctcgtgc cgcaaaaaaa
   142741 atgtttgaat aatcaagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacaacc
   142801 aggctaaaac agcttcttat gtttttgatt tggttggact tattaccgca gatgcaagct
   142861 tttgaacacc gtttaccaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
   142921 cccaagctaa aactgcttct tatgtttttg acttggttgg acttattacc gcagatgcaa
   142981 gcttttgaac accatttacc aagaggttat gaaaaagctg ccctgcatca agtaataaga
   143041 gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt accgcagatg
   143101 caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt tcgagtatga
   143161 agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt aataccgaga
   143221 aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt gaaaacaact
   143281 attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac aactatttca
   143341 atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa tacataagac
   143401 tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa gatctccttt
   143461 aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg aaaggagcat
   143521 ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga aacgtagatg
   143581 atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca gccatttgcg
   143641 gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg tatgttgtag
   143701 gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca ttgaaaaaag
   143761 ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc tgcctgaatc
   143821 acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg cttttcggat
   143881 ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga gttccttatg
   143941 cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa gttttatttc
   144001 tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta aaaaaaggcg
   144061 atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa ttcgctgtta
   144121 tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta gataaagcgg
   144181 ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct ggaacagaat
   144241 tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga atggacggat
   144301 tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc acaatctctc
   144361 cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta actggtgttt
   144421 atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat atcgctgtca
   144481 agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg attgcagaag
   144541 gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa gcagcacaag
   144601 catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg aaaccttgaa
   144661 ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat acccatgaga
   144721 tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc ttctatttcc
   144781 aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt ttctatattt
   144841 ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat ttttatttgg
   144901 ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac atttttattt
   144961 acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga gaatttttca
   145021 aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag cggtcgtccc
   145081 actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa acgtggtatg
   145141 atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc tgatttccgc
   145201 taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca gggcacaaag
   145261 atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg ctcctccgac
   145321 gatggtttct ttttcatcta agaccacata ccattgagga atactttcct tattagcgat
   145381 tccagtacga atactttcct catacacaac agcaggaact ccccattttg atgaaaacca
   145441 attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt tatatgtaac
   145501 caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag tctttatgaa
   145561 aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc acttgttctc
   145621 cgttttttga ttgatcaagc atctaaagct tcttttcttc tttcttggat cgtagctacc
   145681 ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc tagtacacca
   145741 cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac ccatggaggc
   145801 ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac actaactaag
   145861 accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat aggtaaccca
   145921 aacatcgttg gttcattaat attgaaggac acctggcgca atcgacaagt ttgttacaac
   145981 catatatggt ttgtttttac gtcctactaa ataaatagct aacagtaaac ctaaagttgc
   146041 acctgttcct cctaagttga caaagctgtc aaagaaaggt ttgttcacga taaacggtgc
   146101 gctatgccca gctgcgattg cattaacgtt tgcttcaatg gctggcgcat tgattgtttg
   146161 catcaaagga tcgaccatat tcgctccgtg taaaccaaag aaccataaga atggtgtgat
   146221 aaatgcaagc agtaaggcag atggataaga gtttgcaagt cccataaatg gttcttggac
   146281 cactgtatag aaagaaccta cgatatcatc aacaccgaat gcagcaaaaa ttgcagcaac
   146341 taaagcaaac gcagagatag tgatcattgc tggtagtaat gaagcaaatg cttttgcaac
   146401 tgccggtggc acaccatcag gcattttgat gatcaatttt tcatttccgc ttaaacgtac
   146461 aaagatttct gttgaaataa tcccaacaat aatagcaata aacaaaccgt ttgagctcat
   146521 acctaatgct ccgcctaaag cgaagaaaga gcctaaagaa atcacacctg cggaaacacc
   146581 gtcttttcgg tagccgttag ctaaatgata agcaagcaag aaagcaatca agacagaaag
   146641 aatggcaaat gtaccgttcc aagcagcagc cccgaatcct ttccatgatt caccaccaaa
   146701 aattgagttc atcaattctt ggaacccggg aatcggtaag ttattgatca ttactgctaa
   146761 tgctcctaag atcattaacg gcatactcac cataaatgag tcccgaatcg caactaaatg
   146821 ccgttgtgca ccaatttttg atgctacagg tataaaatgt ttctccataa atgcaacaaa
   146881 tttatccata aatcttccct cttttcttta ctgtagatta cgcgttcaat cgacgataca
   146941 gatcaatgat ctcttttgct aaatctgtaa aagctataga tgtcatcaga tgatcttgac
   147001 tgtggaccgt caaaagcgtg acttcaacgt gatttccttg tgcttcttgt gtcagcatct
   147061 ctgtttgaga gtgatgtgct tggactaaag attcctctgc atctttgatt ttttcatctg
   147121 ctaaagtgaa atcacctttt ttcgcagcag caatcgcttc cattgcatcg ctttttgcat
   147181 ttccgccaaa catgatcaga cccatgatgg cttctagatt tttttgatct tccatttatt
   147241 gtatcctccg ataattttta ttatttgttt attagttttt ctgcttggtc gagtactttt
   147301 tcaccattca tcatgccata gtcagccata ttgattacat ctaaaggaat gcctttaggt
   147361 gctagctttt cagcaaattg attttgcata aagcgtactt gcggtcctaa aagtaaaacg
   147421 tctacatttt tagattctag ttgattatcc gcatctgaag cagatacagc aaagatgtct
   147481 gcttccattc cttttgcttc tgctgccttt tgcatttttg tgactaggag acttgtactc
   147541 attccagctg aacatacaag catgattgtt ttcttttcca ttttaaacac gttcctttct
   147601 atacttacac ttgtatataa gcaagtagcg tgccaacttt aaaagcgctt taaaaagttg
   147661 atatcatcac atttaaggtc tataccaagt tgcatacaca ctaaaaaaga aagcgcacac
   147721 taaacacaca aattaatttt tattaccttt tttcttttaa cgtgcacaaa aaaagttgtg
   147781 acacaaaact tgtcacaact tttttcaaat aaacggtatt caaaagcttg catctgcggt
   147841 aataagtcca accaagttaa aaacataaga tgttgttttt actttgctat tcttattact
   147901 tgatgcagga cagctttttc acaacctctc aataaacggt gttcaatcag ctgaccctgg
   147961 gtattagctc aaaacgctgg attcacaacc tcttttattt caaataacca gtaaatacaa
   148021 tgaacatcta caaaaaactt ctatttattt atagatttcg tcaggcaaat ccaattctct
   148081 cttatcaatc aaagtctgat accacgaagc agattttttc aatgttctgc ttcgttcatc
   148141 gttcaattcg attcgaacta atccatatcg attcttaaat gcattcattg gtgacacaca
   148201 gtcagtgaat gcccataaca tatagccttc gcaatttgcg ccttcttctg ttgctttgat
   148261 caagtaatgc aaatgctgtc cgataaattc gatacggtaa tcatcttgca cgattccttt
   148321 ctcatccata tactgttctt catattctct tcccataccg ttttctgtta tcagccaagg
   148381 gatattatga taattttctt ttagatacat ggctatatca tacatgattt tcggatagat
   148441 ttcccatccc ctggaattat tcattttctt cccaggtaaa tcaaagactt cataatatcg
   148501 ttcaggatgg aaaggtgtct cttcattcca ttgataacga ggggcgcgaa cgcgtttagg
   148561 ataatattga ttgattccaa ggaaatctac tgtatgatgc tgaatcgttt ctaaatcctc
   148621 tgttgcagga tcgaaataaa tcgattgttt ttgacacaac tccaggaact cttctgtgta
   148681 gtatcctttt accatcggat caaaaaatac tcgattataa aacaaatcat acatataagc
   148741 agctttttgg tcttctggag aattggatcg agcatagacc atttcaggat ttaaaataca
   148801 gccaatcctt ccaccataat ttccgctgcg gtaaatctct actgctttag ccgttgctaa
   148861 aactttatga taattccaca tcatccactt ttttgtgttt tgttcatgcg gccagcgaac
   148921 agcatccaaa tagcaacgcg tttggggaac gattggttcg ttgaatgtaa accagttttt
   148981 taccctatca ccgtaacgat caaaggcaat ttgagcatac ttagcataaa aatcaactac
   149041 ttttcttgaa gaccagccat catatttttc caaaagaaaa gctgggactt cataatgttc
   149101 caaacaaatc atcggttcta cgtctgcttc gatcaaagag tcgatcattt cacttatatg
   149161 ctgagcatat tcttcatcta ctatacagtt ctcataatca gtaaaaaaac gagcccaatt
   149221 gatagaagtc cgataatgtg tcagatggat ggatttcatc agatccacat cctgctggta
   149281 ttgttccata aaattagttg ctacggctgg gccataccca ttatgccaaa caaaatgttc
   149341 atttttatac cagctatcta taaacgaatc ctgtccttct ttttttcctt tccaaccttc
   149401 cgtttgccaa gcagaagatg cagcaccaag aataaaattt tttggaatag taattttcat
   149461 gatttcctcc tgttttttag atcccatcat tttccacacg atttgctact tttacaaatg
   149521 gcagatagat caaaatagaa acaataatac aaacaagttg cgtaataact gcaccgatat
   149581 ttcctgctgt tgccagataa gcattgacga tcggcggcat tggccaaggg accattacaa
   149641 ctgctttcgc cgcaaatcct aaagcggttg caaaataacc aatcgttcca gtgataagag
   149701 gcgttaagat aaacggaata gctaaaattg gattcagcat gatcggcata ccaaaaataa
   149761 ctggttcatt gatgttgaag atcccaggag caagggataa cttggtgatt tgtttcatat
   149821 cttcccgttt tccaactaac aatactgcaa tcagtaaacc gatcgtgact ccagacccgc
   149881 ccatactcat atacatatcc caaaatggca tagtaataat gttcggtact tcttttccag
   149941 cttcaaaagc ttccgtattt acagcaattg ccgctaaaag caacggttcc cgtatcggct
   150001 tcaccatttg atttccatgg ataccaatca cccaaaagac ttgcgcaata aacatcaata
   150061 gcaaaatacc cggtaaccct tgtacgacac cttctaatgg gcgttgtacg acattgtaaa
   150121 tgatatcata aaggtacatt cctgtaagtt ctttgatgat aaatcccgca gccgcgatac
   150181 ccgatacagt cagaatcgtc gggaataaag cagaaaaact agcagaaaca ttcgttggca
   150241 cggtatcagg cattctcagc tgtagtttct tctgtttcct caaccagcaa taaagttcaa
   150301 tagaaaggat ggagaccaac attcccaaaa ataacccttt cgtatctgta tattgtttag
   150361 ccaatacgtt ttctactata acagtctgat tttcattcac taattcataa acagttggat
   150421 taacagataa ataagacatc actgcgatga taccagggaa tacaccatcc actttattca
   150481 gcttggctaa ttcgatccct atcagaaaaa cagcatagat ggtcaagaaa cttagtgtga
   150541 catagctgat ggcagatgcg ataggcttta attcttctaa aaaacgcaag aaacttatct
   150601 gtgctaagcc attttccgag tcaaagacca ttgctgaaaa caatgtgcca aaagcacccg
   150661 taataattac cggaatcaat gcagcaaatg cgttttttat caccatgata taccttaaat
   150721 tattgattct cgttgccacg ttccctaaaa cattggctaa tttatccata aaactcattc
   150781 cagatcccct cattcctgct tcttctcctt gacgtcatct ctttttgtct attagtcagc
   150841 gcttacattt cgatgaacag aaactattta ctcctctttt ttaccaaata taaaacaaaa
   150901 attcatctga tgtatttatc ataaaataca tcagatgaac tgtcaattag tttctttttc
   150961 tcctattatt ttctgtaatt ctctccgatt tattgccata tggacagtca ttgcatcaaa
   151021 cgcagcaagt gcattccgcc tttcgatggc ctgaacgatc tctgtatgaa tatcgatcgt
   151081 ctcgattttc agatgctgga tatcataatt tttattaaac aaagcaattg attcattaat
   151141 gattgggata atatgcagca aggctacgtt tccgctagct tctgcaatca tcgtatgaaa
   151201 atcgatgtct aattgaacat gttcttgtgt gccttctcga aaagaagttt caatcttttg
   151261 cgttaatttt ttcatttgga cgatttgatt cttcgttgca tattccgctg ccaaacctgc
   151321 catcttaggc tccaataaat atctcagttc aaataagtct cgtatcatcc gatcctgatc
   151381 ttcaatcaaa gaaaaaccga gtgggtcatt ggcaatccct cgcttatcac tgacaaatgt
   151441 ccccgctcct tgccgaactt caaggatatt cctggaagct agagcccgca cagcttctcg
   151501 caccgtgctt cgccccacct ctaaataatc ggacaattca tattcattcg gcagtttatc
   151561 tcctacttgc aactgcattt cctttaaata tctaaggatc ttgtcagtag ttacttctac
   151621 tagggtttta ttttcttcca aaccacatac ctccttttca tctgatgtat tttttcgtaa
   151681 ttattataac acgtttgaat catctgatga ttttttgtat acaaaattga ttaatccgtt
   151741 catagacata caaacgaaga agatatttac cataaaaaag actaggataa aattcactcc
   151801 tagccttcga tcatttttat tttgaacgac aaaaaatatg atgttcaata acagacgatc
   151861 ttcattcgat tcttgatgtc atcttttgtt ttttttaata tatggataaa aagtttgatt
   151921 acatcgtttc tattctagaa tttggtcgat tctcaattct tcttctggtg agaaatctaa
   151981 attatccatc attcgaacac tttcttgtaa ctgacttaac cgacttgctc cgaccagtac
   152041 acttgtaaca gatttttgtc gcaaattcca tgcaagggcc atttgcgcta atgattgtcc
   152101 tcgtgatacg gcgattgttt gcagtgcttt gattttttcc agagttgatc caacttgttc
   152161 ttctgaaagg aatggtattt ccttacgatg tgctctagaa tcttcaggaa taccatgtag
   152221 ataacgattt gtcagcaacc cttgagcaag cggactgaac gtgattgccc ctagcccttc
   152281 ttcttctaat actggagata gatcgtcttc tagtagtgca cgagaaaaca tattgtagcg
   152341 catctgatga ataatgaacg gtgcttcctt tctttttaaa atttcagtca ttttttttgt
   152401 atcttctcca ttatagttgg atataccaat atataatgct tttccttgtc ttacaagttg
   152461 catcaaagct tctgctgttt cttccaaagg tgtatcaggg tctgggcgat gatgatagaa
   152521 gatgtcaaca taatctagcc ccattctttg gagactttgg tcacaacttg aaatgatgga
   152581 tttacgagag ccccattccc catatggccc ttcccacata tgataacctg ctttgctaga
   152641 aataatcagt tcatcacggt aggcttgaaa atcttctcta aaaatacgcc caaagttttt
   152701 ctctgcagct ccagcagggc ctccataatt attcgcaagg tcgaaatggg taattcccat
   152761 gtcgaatgcg cctcttaaaa tctctctttg attatggata ggatcataat caccaaaatt
   152821 ttgccataat ccgagagata aaatcggtaa tttcaaacct gaatgaccgg atttacgata
   152881 ttccattttt tcataacgtg cactatctgc aatatacaat ttttctcctc ctcatcaaat
   152941 ctttttaaaa cgctttcttt tttctatttt tagtttacta cattttaaag aaaaggagtt
   153001 aatcaaaatg attttttcgt atattttttt gccatttgtt ttttactcgt tgatagatca
   153061 gaaattgatt acgtgcttgc tggatttttt tataacgttt cggttgtttt ttgtaaaatt
   153121 gctgatgata gttttctgct ggccaaaacg taccggctgg ttcgattttt gtgacgattg
   153181 gttggtggaa agttcctgaa ctgtctagtt tctgttttga ttgttccgct aattcttttt
   153241 gtcgttcgcc ttgataaaaa atcactggac gatattgctt ccctctatct tgaaattgtc
   153301 caaatgtatc tgtgggatca gtaatttgcc aatagattgt cagcaactcg ctataactta
   153361 tttctcttgt gtcataaatg atctccacag cttccacatg acctgtgtaa ccaccactta
   153421 cttgatcata atttggtttt tcaacatgtc cgcccgtgta tcctgacaaa acagatagga
   153481 tccctttttt cgattcaaac ggctcgacca tacaccagaa acatccccct gcaaatactg
   153541 cacgttcttg atagtcagca tcttgcatgg catgcttgga aaagtcatat ttttgctcct
   153601 tatcaaatcc ttccgtaatc aataaataaa agtccattac atcaggcgtc agattcattc
   153661 ggatagctaa tggacgtagt gttgcttcta gttttgataa ctgttcttta acggatatat
   153721 tttctcttat gtcattcttt gtctgaatca atacttttcg ttcccaatct cgtgtattcg
   153781 gattcaaaat cagattataa agtgtttgaa tgaatatttg ttcctcatcc atagattctc
   153841 ctcctttccg aagaagacaa gctagtgact ttagctgtaa tttatcataa agtgaggaaa
   153901 taagcgatta cttcatcccc ctacagattt ttcgtataaa aaagagagaa tccttatcga
   153961 cagattctcc tttttaatca atttatttta taaatgaaaa gttaatttac cttttatgga
   154021 aaactatttt aaaaaataaa cataaatatg cagttaatgt aacaagataa gaaataatag
   154081 tcgttactgt ataacttgtg cttactttaa tatcagcaac tcctttgact ccgcttattt
   154141 gtaccaatcc attagcattc acctgctcct ttacaggttg atgatttatt tctacattcg
   154201 ttcctaaata agcatataca ggaagtgtga ttacttggct cttctcatta gttactctat
   154261 atatgataga actaccagtt gttttataag gaaggtttac ccattgactg ccaatctttg
   154321 cttcgtgttt tattatatgc tccttattct ccaatgaagc gataggagaa taatcatata
   154381 aaaaataatc cattccttta gtggtatacg cctctactgt ttctttgttt acaacaatat
   154441 gtcccggctg agaaattatt ttttgattga aatttttttt actagaaaca gttaaagtga
   154501 ttaataacaa aacagtcata aataaataaa atagttctct tgtcttattg tatcttctat
   154561 ttttgaaaaa tatcatcgtt aatatcagag aagagaatat tatttgcaag cttaagatcc
   154621 gccaaggaaa ttgtaacaat ttggctggcg tattttgcag aagataccat ggcaccaaac
   154681 tagttgtagc tagccaagtc aaacacgtac cataataaat ctttttttct atgtttgtta
   154741 attttttaaa taaaatcagg ggaatacata aagataacag accaactagt cccattgagt
   154801 aagtagttaa gtcgttgttc atagcttcag tcagactatc gaacacatta gatgcatgag
   154861 catataaatt tgtcacgcta ggtttgttga ttttttggta gagcatttgt tcaaacatcg
   154921 gataccaaaa agcactcgtc agaaccaatg tcattcctgc cgcactaaat aattttttaa
   154981 atatagcaat aaaatctgca ttcttgaaac ctttagaaac caaacgaata aaaatgataa
   155041 ttaatgctgt actcattaat gttgatagta catggctgta cactagcaaa ctcatactca
   155101 atgctagctt tacagacgga tacttttctt cttttccaga gatgatttga taagcataaa
   155161 ataatacagg gataacaagt gttattgcga tagcttcggc aattgcggaa cgatagtaga
   155221 tgtctactgt ccgataagca gagaaaatat agagacaact aaataaaaat gccgcttttt
   155281 tttgttttaa aaaccgctcg ccataatgat aagctacgag tgttgtacac aagttcaata
   155341 accaaacgta aataatatag cttacaatca aattttttgt catccaatat aacattacag
   155401 ctggaaaaaa agtcagaaag ggataaaaat aatttacacc atatccagta taattgaatg
   155461 tctcataatt aatcggactg gtaaaaatag tcgataaccc cttgattcga gataagtgaa
   155521 aagaaagatc tccagtggta taaatactct gtgtattttt gaaaaagatg aaagaatata
   155581 tactactaac tataatt
//
LOCUS       DASHWW010000002        99407 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.002, whole genome shotgun sequence.
ACCESSION   DASHWW010000002 DASHWW010000000
VERSION     DASHWW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 99407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.002"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            10..588
                     /locus_tag="U2R64_000137"
     CDS             10..588
                     /locus_tag="U2R64_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916990.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(828..911)
                     /locus_tag="U2R64_000138"
     tRNA            complement(828..911)
                     /locus_tag="U2R64_000138"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(875..877),aa:Leu,seq:gag)
     gene            966..1145
                     /locus_tag="U2R64_000139"
     CDS             966..1145
                     /locus_tag="U2R64_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8916991.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1294..2511
                     /locus_tag="U2R64_000140"
     CDS             1294..2511
                     /locus_tag="U2R64_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8916992.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2695..3531
                     /locus_tag="U2R64_000141"
     CDS             2695..3531
                     /locus_tag="U2R64_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8916993.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     NEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3607..4755
                     /gene="nagA"
                     /locus_tag="U2R64_000142"
     CDS             3607..4755
                     /gene="nagA"
                     /locus_tag="U2R64_000142"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEM8916994.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4976..6034
                     /locus_tag="U2R64_000143"
     CDS             4976..6034
                     /locus_tag="U2R64_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HEM8916995.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6038..7072
                     /locus_tag="U2R64_000144"
     CDS             6038..7072
                     /locus_tag="U2R64_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HEM8916996.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7174..7890)
                     /locus_tag="U2R64_000145"
     CDS             complement(7174..7890)
                     /locus_tag="U2R64_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEM8916997.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7859..8644)
                     /locus_tag="U2R64_000146"
     CDS             complement(7859..8644)
                     /locus_tag="U2R64_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HEM8916998.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8635..9384)
                     /locus_tag="U2R64_000147"
     CDS             complement(8635..9384)
                     /locus_tag="U2R64_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEM8916999.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9682..10206
                     /locus_tag="U2R64_000148"
     CDS             9682..10206
                     /locus_tag="U2R64_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HEM8917000.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIRE
                     RICYVMPYESMIKA"
     gene            10222..11721
                     /locus_tag="U2R64_000149"
     CDS             10222..11721
                     /locus_tag="U2R64_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HEM8917001.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11809..12411)
                     /locus_tag="U2R64_000150"
     CDS             complement(11809..12411)
                     /locus_tag="U2R64_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8917002.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12515..13471
                     /locus_tag="U2R64_000151"
     CDS             12515..13471
                     /locus_tag="U2R64_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEM8917003.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13776..14732)
                     /locus_tag="U2R64_000152"
     CDS             complement(13776..14732)
                     /locus_tag="U2R64_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8917004.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFVSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14906..15466
                     /locus_tag="U2R64_000153"
     CDS             14906..15466
                     /locus_tag="U2R64_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917005.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15459..16283
                     /locus_tag="U2R64_000154"
     CDS             15459..16283
                     /locus_tag="U2R64_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEM8917006.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16293..16910
                     /locus_tag="U2R64_000155"
     CDS             16293..16910
                     /locus_tag="U2R64_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEM8917007.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16928..17611
                     /locus_tag="U2R64_000156"
     CDS             16928..17611
                     /locus_tag="U2R64_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEM8917008.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18294..19577
                     /locus_tag="U2R64_000157"
     CDS             18294..19577
                     /locus_tag="U2R64_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917009.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19593..20480
                     /locus_tag="U2R64_000158"
     CDS             19593..20480
                     /locus_tag="U2R64_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8917010.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20497..21333
                     /locus_tag="U2R64_000159"
     CDS             20497..21333
                     /locus_tag="U2R64_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8917011.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21336..21959
                     /locus_tag="U2R64_000160"
     CDS             21336..21959
                     /locus_tag="U2R64_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917012.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21956..23248
                     /locus_tag="U2R64_000161"
     CDS             21956..23248
                     /locus_tag="U2R64_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8917013.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23607..23704
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23820..24401
                     /locus_tag="U2R64_000162"
     CDS             23820..24401
                     /locus_tag="U2R64_000162"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEM8917014.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24404..25711
                     /locus_tag="U2R64_000163"
     CDS             24404..25711
                     /locus_tag="U2R64_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEM8917015.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26127..26615
                     /gene="purE"
                     /locus_tag="U2R64_000164"
     CDS             26127..26615
                     /gene="purE"
                     /locus_tag="U2R64_000164"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEM8917016.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26608..27732
                     /gene="purK"
                     /locus_tag="U2R64_000165"
     CDS             26608..27732
                     /gene="purK"
                     /locus_tag="U2R64_000165"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEM8917017.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27745..29040
                     /gene="purB"
                     /locus_tag="U2R64_000166"
     CDS             27745..29040
                     /gene="purB"
                     /locus_tag="U2R64_000166"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEM8917018.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29220..29597)
                     /locus_tag="U2R64_000167"
     CDS             complement(29220..29597)
                     /locus_tag="U2R64_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917019.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29853..30581
                     /locus_tag="U2R64_000168"
     CDS             29853..30581
                     /locus_tag="U2R64_000168"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEM8917020.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30581..30835
                     /gene="purS"
                     /locus_tag="U2R64_000169"
     CDS             30581..30835
                     /gene="purS"
                     /locus_tag="U2R64_000169"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HEM8917021.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30837..31508
                     /gene="purQ"
                     /locus_tag="U2R64_000170"
     CDS             30837..31508
                     /gene="purQ"
                     /locus_tag="U2R64_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HEM8917022.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31509..33731
                     /gene="purL"
                     /locus_tag="U2R64_000171"
     CDS             31509..33731
                     /gene="purL"
                     /locus_tag="U2R64_000171"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HEM8917023.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33716..35155
                     /locus_tag="U2R64_000172"
     CDS             33716..35155
                     /locus_tag="U2R64_000172"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEM8917024.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35178..36230
                     /locus_tag="U2R64_000173"
     CDS             35178..36230
                     /locus_tag="U2R64_000173"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEM8917025.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36227..36805
                     /gene="purN"
                     /locus_tag="U2R64_000174"
     CDS             36227..36805
                     /gene="purN"
                     /locus_tag="U2R64_000174"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEM8917026.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36802..38337
                     /gene="purH"
                     /locus_tag="U2R64_000175"
     CDS             36802..38337
                     /gene="purH"
                     /locus_tag="U2R64_000175"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEM8917027.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38353..39627
                     /gene="purD"
                     /locus_tag="U2R64_000176"
     CDS             38353..39627
                     /gene="purD"
                     /locus_tag="U2R64_000176"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEM8917028.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39749..40663
                     /locus_tag="U2R64_000177"
     CDS             39749..40663
                     /locus_tag="U2R64_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8917029.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40796..42361)
                     /locus_tag="U2R64_000178"
     CDS             complement(40796..42361)
                     /locus_tag="U2R64_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEM8917030.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42354..43805)
                     /locus_tag="U2R64_000179"
     CDS             complement(42354..43805)
                     /locus_tag="U2R64_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8917031.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43819..44835)
                     /locus_tag="U2R64_000180"
     CDS             complement(43819..44835)
                     /locus_tag="U2R64_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8917032.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45055..46143
                     /locus_tag="U2R64_000181"
     CDS             45055..46143
                     /locus_tag="U2R64_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEM8917033.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46197..47723
                     /locus_tag="U2R64_000182"
     CDS             46197..47723
                     /locus_tag="U2R64_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEM8917034.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47725..48930
                     /locus_tag="U2R64_000183"
     CDS             47725..48930
                     /locus_tag="U2R64_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8917035.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49187..50164
                     /gene="guaC"
                     /locus_tag="U2R64_000184"
     CDS             49187..50164
                     /gene="guaC"
                     /locus_tag="U2R64_000184"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEM8917036.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50428..51852
                     /locus_tag="U2R64_000185"
     CDS             50428..51852
                     /locus_tag="U2R64_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEM8917037.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52313..53422
                     /gene="pdhA"
                     /locus_tag="U2R64_000186"
     CDS             52313..53422
                     /gene="pdhA"
                     /locus_tag="U2R64_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HEM8917038.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53425..54402
                     /locus_tag="U2R64_000187"
     CDS             53425..54402
                     /locus_tag="U2R64_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEM8917039.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54427..56070
                     /locus_tag="U2R64_000188"
     CDS             54427..56070
                     /locus_tag="U2R64_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HEM8917040.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56078..57484
                     /gene="lpdA"
                     /locus_tag="U2R64_000189"
     CDS             56078..57484
                     /gene="lpdA"
                     /locus_tag="U2R64_000189"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEM8917041.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57646..57921
                     /locus_tag="U2R64_000190"
     CDS             57646..57921
                     /locus_tag="U2R64_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEM8917042.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57927..58694
                     /locus_tag="U2R64_000191"
     CDS             57927..58694
                     /locus_tag="U2R64_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEM8917043.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58862..60691
                     /gene="typA"
                     /locus_tag="U2R64_000192"
     CDS             58862..60691
                     /gene="typA"
                     /locus_tag="U2R64_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEM8917044.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60952..62724
                     /gene="recQ"
                     /locus_tag="U2R64_000193"
     CDS             60952..62724
                     /gene="recQ"
                     /locus_tag="U2R64_000193"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HEM8917045.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGRNKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62838..63140
                     /locus_tag="U2R64_000194"
     CDS             62838..63140
                     /locus_tag="U2R64_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HEM8917046.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63143..64306
                     /locus_tag="U2R64_000195"
     CDS             63143..64306
                     /locus_tag="U2R64_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEM8917047.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64332..67760
                     /locus_tag="U2R64_000196"
     CDS             64332..67760
                     /locus_tag="U2R64_000196"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HEM8917048.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            67781..68905
                     /locus_tag="U2R64_000197"
     CDS             67781..68905
                     /locus_tag="U2R64_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917049.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68895..69332
                     /locus_tag="U2R64_000198"
     CDS             68895..69332
                     /locus_tag="U2R64_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEM8917050.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69316..69654
                     /locus_tag="U2R64_000199"
     CDS             69316..69654
                     /locus_tag="U2R64_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEM8917051.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69773..70333
                     /gene="rsmD"
                     /locus_tag="U2R64_000200"
     CDS             69773..70333
                     /gene="rsmD"
                     /locus_tag="U2R64_000200"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEM8917052.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70330..70821
                     /gene="coaD"
                     /locus_tag="U2R64_000201"
     CDS             70330..70821
                     /gene="coaD"
                     /locus_tag="U2R64_000201"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEM8917053.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70811..71854
                     /locus_tag="U2R64_000202"
     CDS             70811..71854
                     /locus_tag="U2R64_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEM8917054.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72013..72741
                     /locus_tag="U2R64_000203"
     CDS             72013..72741
                     /locus_tag="U2R64_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEM8917055.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            72857..73102
                     /locus_tag="U2R64_000204"
     CDS             72857..73102
                     /locus_tag="U2R64_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEM8917056.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73099..73317
                     /locus_tag="U2R64_000205"
     CDS             73099..73317
                     /locus_tag="U2R64_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEM8917057.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73453..73992
                     /locus_tag="U2R64_000206"
     CDS             73453..73992
                     /locus_tag="U2R64_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HEM8917058.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            73985..76258
                     /locus_tag="U2R64_000207"
     CDS             73985..76258
                     /locus_tag="U2R64_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEM8917059.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76296..77342
                     /gene="holA"
                     /locus_tag="U2R64_000208"
     CDS             76296..77342
                     /gene="holA"
                     /locus_tag="U2R64_000208"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEM8917060.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77431..77685)
                     /locus_tag="U2R64_000209"
     CDS             complement(77431..77685)
                     /locus_tag="U2R64_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEM8917061.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78085..78354)
                     /locus_tag="U2R64_000210"
     CDS             complement(78085..78354)
                     /locus_tag="U2R64_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917062.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(78824..79279)
                     /locus_tag="U2R64_000211"
     CDS             complement(78824..79279)
                     /locus_tag="U2R64_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HEM8917063.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(79417..81345)
                     /locus_tag="U2R64_000212"
     CDS             complement(79417..81345)
                     /locus_tag="U2R64_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEM8917064.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(81542..82375)
                     /locus_tag="U2R64_000213"
     CDS             complement(81542..82375)
                     /locus_tag="U2R64_000213"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEM8917065.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(82567..83271)
                     /locus_tag="U2R64_000214"
     CDS             complement(82567..83271)
                     /locus_tag="U2R64_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8917066.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(83294..83920)
                     /locus_tag="U2R64_000215"
     CDS             complement(83294..83920)
                     /locus_tag="U2R64_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8917067.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            84246..86621
                     /locus_tag="U2R64_000216"
     CDS             84246..86621
                     /locus_tag="U2R64_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HEM8917068.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(86645..87136)
                     /locus_tag="U2R64_000217"
     CDS             complement(86645..87136)
                     /locus_tag="U2R64_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HEM8917069.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            87323..88243
                     /locus_tag="U2R64_000218"
     CDS             87323..88243
                     /locus_tag="U2R64_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8917070.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            88397..88741
                     /locus_tag="U2R64_000219"
     CDS             88397..88741
                     /locus_tag="U2R64_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEM8917071.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(88931..89431)
                     /locus_tag="U2R64_000220"
     CDS             complement(88931..89431)
                     /locus_tag="U2R64_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917072.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            89959..90042
                     /locus_tag="U2R64_000221"
     tRNA            89959..90042
                     /locus_tag="U2R64_000221"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:89993..89995,aa:Leu,seq:cag)
     gene            complement(90366..91004)
                     /locus_tag="U2R64_000222"
     CDS             complement(90366..91004)
                     /locus_tag="U2R64_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8917073.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            91339..91773
                     /locus_tag="U2R64_000223"
     CDS             91339..91773
                     /locus_tag="U2R64_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8917074.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            91796..92116
                     /locus_tag="U2R64_000224"
     CDS             91796..92116
                     /locus_tag="U2R64_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917075.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            92257..92448
                     /locus_tag="U2R64_000225"
     CDS             92257..92448
                     /locus_tag="U2R64_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917076.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(92519..92776)
                     /locus_tag="U2R64_000226"
     CDS             complement(92519..92776)
                     /locus_tag="U2R64_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HEM8917077.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            92934..93197
                     /locus_tag="U2R64_000227"
     CDS             92934..93197
                     /locus_tag="U2R64_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917078.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            93221..93409
                     /locus_tag="U2R64_000228"
     CDS             93221..93409
                     /locus_tag="U2R64_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917079.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(93492..93677)
                     /locus_tag="U2R64_000229"
     CDS             complement(93492..93677)
                     /locus_tag="U2R64_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917080.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            93892..94263
                     /locus_tag="U2R64_000230"
     CDS             93892..94263
                     /locus_tag="U2R64_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8917081.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(94413..94485)
                     /locus_tag="U2R64_000231"
     tRNA            complement(94413..94485)
                     /locus_tag="U2R64_000231"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(94450..94452),aa:Gln,seq:ctg)
     gene            complement(94531..94959)
                     /locus_tag="U2R64_000232"
     CDS             complement(94531..94959)
                     /locus_tag="U2R64_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917082.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(95019..95777)
                     /locus_tag="U2R64_000233"
     CDS             complement(95019..95777)
                     /locus_tag="U2R64_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEM8917083.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            96072..96269
                     /locus_tag="U2R64_000234"
     CDS             96072..96269
                     /locus_tag="U2R64_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917084.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            96375..96857
                     /locus_tag="U2R64_000235"
     CDS             96375..96857
                     /locus_tag="U2R64_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917085.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(96915..97511)
                     /locus_tag="U2R64_000236"
     CDS             complement(96915..97511)
                     /locus_tag="U2R64_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEM8917086.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            97898..99364
                     /locus_tag="U2R64_000237"
     CDS             97898..99364
                     /locus_tag="U2R64_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HEM8917087.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        32263 a        17024 c        21144 g        28976 t
ORIGIN      
        1 tttttagaca tgaatatctt atttttattg ctatttttct taattttcct tctaacatat
       61 aggaaatgtc aaaactatta tgtgcgtata ttgactgcat taccgttttt cttaaacctg
      121 attatttatt ttggtaatac aatgggtcaa agctttactt acgtcaatgg aaataaaagg
      181 gcaatgattt ggagtagtag taacctgaat aatctcttta cagagttagg aacgaaactg
      241 tcactttttt atccaggtac ttggatagct actttagtag tcttggcatt attactatgt
      301 ttaattgttg gaatttattt aagttttgac aataagaaaa cttctatttt tttagttatt
      361 ttgatgataa tgggattttg ttcaaggtta attatgggat tttctcccac agtatgggct
      421 tccggaatgc ggacgtacta tatactttat gttgttatcg ccatcttagt actaatggca
      481 gttaaagagc taatgaaaag catgagtgta caaaaaaatg aatttatgca atttggatta
      541 accgtgcttg gtatttgtac ctttataata acggtgataa acagataata tacaaaaaat
      601 ccctcgcttt agtattaggt gagggatttt actcgttttt cgattaattg ttttaacact
      661 tgcaagtttc tacgagtagc ttgtttccga ccttcatata ctcacctcag gctgtttaca
      721 tgattgtacg ttctttttgt aaaggataca gtgatatgta tataatggca taaagaaacg
      781 ttcaaacaaa aaaactcgtg aagcaaaatt aacttcacga gttgtagtgc agatgatggg
      841 actcgaaccc acacgagcta acgctcacat gaccctcaat catgcttgtc tgccaattcc
      901 aacacatctg cgtaataata acacactaat gatagcgagg ttttacatag ttgtcaagct
      961 caaaaatggg aggacttatt aagatggaga aatatgacgg agaattttca ggactgggaa
     1021 tgatcttagg tgtattgatt ggacttgcat tcggacgttt tttgcttggt tttatgctag
     1081 gaatcatttg tggaatcgca atggattggg cagcgaatct atggaatgac tatcatgaca
     1141 attaagttct caacgcttgt ttgtgttttt ttaatactta cgtttttcct aaataagtgg
     1201 caaaattttc taggatggag tatgatattg aaatagtaaa taacaaaaaa tttggaaagt
     1261 tctaactttt tgaaatgagg gattggctaa gtgatgagag aatttgaaaa atccaacaaa
     1321 ttagaaggtg tcagttacga tgttcgcggt cccgttctag aagaagcgga gcggatgcaa
     1381 gaagagggca ttagtatttt aaaattgaac acgggaaatc ccgcaccttt tggatttgaa
     1441 gcaccaaacg aagtcattcg tgatttgatc atgaatgccc gtgactcaga aggctactca
     1501 gattccaagg ggatcttttc tgctagaaaa gcaattgagc aatattgcca actgaaacat
     1561 tttccgaatg tgacgatcaa tgatatctac accggcaacg gagtgagcga attgatcacg
     1621 atgtgtatgc aggggttgct ggacaatgga gatgaagtac tggttccaat gccggactat
     1681 ccgttgtgga cggcttctat tgcattagct ggaggcacac ctgttcatta tatttgcgat
     1741 gaagaggcag aatggtatcc tgatattgat gatatcaaat caaaaataac gagtcggaca
     1801 aaagctattg ttatcattaa tcctaataat cctactgggg cactttatcc aaaagaatta
     1861 ttagaagaaa tcgttgaagt agctcgacaa aataacctga ttatttattc cgacgaaatc
     1921 tatgatcgct tagtgatgga tggtctagaa catattccga ttgctacatt agcgcctgat
     1981 ttgttcgttg ttacgctgaa cggtctatcc aaatctcatc gtgtagcagg atttcgagta
     2041 ggctggatgg tcctaagtgg agataagtca cacgtcaaag gctatataga agggctgaat
     2101 atgttgtcct ccatgcgttt gtgttccaat gtattgtctc agcaaattat ccaaaccgcg
     2161 ctaggcggtt atcaaagtgt cgatgagctg ctcctgccag gcggaaggat ctatgaacaa
     2221 agagaatata tctataatgc aatcaatgat attcctggtc tttcagccgt aaaaccaaaa
     2281 gctgcttttt atatattccc aaaaattgat acaaagcgat tcaatatttt ggatgatgaa
     2341 aaattcgttt tggacttttt acatgaacat catattctac ttgtacatgg tggtggattt
     2401 aattggaacc agccagatca ttttcgaatc gtttatcttc ctaaaatgga tgatttgaaa
     2461 caaacagcta agaaaatgag agaattccta gcaacctatc gccaaaaatg attttaaaaa
     2521 ccaaattttt cagtaggagg gccacagaca aacacactga ggctctcttt ctagtggagt
     2581 tttcttaaat aactaaagta tattatttag ttgcaagtct tttcttgaag tttgcgactt
     2641 cctaaagtaa aatacgaata gaatgcgaat acgcatattt tggggaggat acttatggaa
     2701 acgttaatcg agtcctttgg aacgatcatt aaagagattc gaaaagaaca aaaaatgacg
     2761 caaaaaatgc tttcgcatga tatttgttca caaagtgtat taagtcggat cgaaaataat
     2821 gaggaactgc cgaatgtatt ggtgatgatg cagatttgtc aacggctagg ggtaacgatt
     2881 gatcatgtga tgaatctctc tcgaaaaact actcggacaa acgataaatt atttgaactg
     2941 ttggatagtt gtttccaaaa acgtgattat cggaagttag aacaagtact aaaatcttct
     3001 gatatttctg aaaatctgta tcaagcaact gactttcaac gctattatta ttatctcggt
     3061 gtttgcgaat tcacgttgcg tcaaaatatc tctcagtccc tttattattt gaaagaagca
     3121 ttaagctact ctagccaaaa agaaagaatc catgtttctg acacagaaat acaactgatt
     3181 agttgtatcg gaaaaatata tggtgtggca ggaaaaacgg ctgaagcacg ctactatttg
     3241 agtcgaagca tccaactgct gcatcaatca gctgatgaac gatcaaaaag tgaattttcg
     3301 caaatttttt ataattatgg aaatttctta ttccatcaaa atgaaatcaa cgaagcgtta
     3361 gaacaggtga atcaaggaat ctattgggct caagagaaga atagctacta ttacctcaat
     3421 gatttatttg tgcttaaaag cttaatatac aagcgtaaag aagaaccaga aagagcagca
     3481 ttctatgaag gcttagcaca agctgtgaaa caaatttcaa aaaatttgta aatggtgtag
     3541 accattcttg acttcttctc taaataagag tactttagag gtagaaaaac aaagggagag
     3601 aatagaatga gaacttttat ctatgctgac aaattctttt tagcgtcagg tgtcaaacat
     3661 gcaggctatc ttgaaattac cgatggactt tttggtgaat acaccaaaga actacctgag
     3721 ggagaagtca acatcattga ccaaagcggc aaatggattg ctcctggttt ggtagataca
     3781 catattcacg gctatatgaa tcatgatgta atggataatg atgcagaagg catcaaagtg
     3841 atgtctgaag gtctgttatc ttgtggagtg acttcatttt taccaacaac attgacgtca
     3901 agcaaagaac gtttaaaaga tgtagctgag acaatcggca aaatgtatca ggaagcacca
     3961 ggagctaaaa tcaaaggaat ctattttgaa ggtcctttct tcacagaaga acacaaaggg
     4021 gcacaaaacc caagttattt cggggatcct gatttggata ctttccatga atggcaagaa
     4081 gcttcaggtg gtttaatcaa aaaaattgct ttagcaccgg aacgtcaagg tgtagaagag
     4141 tttgtcaaac aagtgactga agaaggagta gttgtttctc taggacacag taatgctaca
     4201 ctagaagaag cgcaaaaagc tgttgaagca ggcgcaagtg tatttgtcca tgctttcaat
     4261 ggtatgcgtg gattgaatca tcgcgaacca ggtatggtgg gtgcgttatt atctttagaa
     4321 catgtctttt ctgaattgat ttgtgatggc catcatgtac atccaaatgc tgcgggaatc
     4381 ctaatggaaa aagcaggaca tgatcatgtc gcattaatta cagactgtat gatggccggt
     4441 gggatgcctg atggaaatta caatttaggc gaatttccag tagtagtaaa agaaggaaca
     4501 gcacgtctag aatctggcaa cttagctgga agtatattga aattgaaaga agcaattaaa
     4561 aatgttgtag actggggatt agcaacacca gaacaagcag tcatgatggc tagtctgatt
     4621 ccagcaatca gctgtaaaat cgatgataca tgtggaaaaa tcgctcaagg acgcgatgca
     4681 gactttatcg tattgaaccc tgatatgaca ttggaagcaa cttatctaga tggcgtggaa
     4741 cgtttccacg cataatataa tttaagttaa ccttaaaact aaacttctta agtttggttt
     4801 taaggttttt tttgtgttct agtaaaaatc actttacata agtttcaaaa gtttctttaa
     4861 tttcctattg ttcaataagt aacaatgtaa agataaaatt aaaaatgtta atacgtatta
     4921 gcaaaataaa agcttttttt attgtgaata aatgaacata attaggagga gaaagatgaa
     4981 cttatttgac atttttcgat cgactttgac agatatgtcg attgtcagtg caatcacttc
     5041 aacagttttt attatattat tagggtttgt ttgtagaaaa aaggggattt tttctgaatc
     5101 tgttggaaaa attctatcga aagtcgtctt aacagtggct ttgccagcac tggcatttcg
     5161 agctttcatg caagatatca atacagaatt actgatgcaa ggaatcaatg tcttgatttg
     5221 gggattagtt atttatatta ttcttattct agtttcaaaa ccttttttct taagctataa
     5281 aggggataag caaacaacgt tgcgtgtcct gacgatcttt ggttctacga cctttttcgg
     5341 aacgcctatc gtcagtgcga tttatggtcc tgtcggcgtg atgtattcct caattttcaa
     5401 tattggctac cgaatctttt tgtattctta tggatacata aaaatgagtg gcttgaagat
     5461 ggaagctaaa aatatcaaag cgatgttcgt caatccaatc attatcgcta cttttgccgg
     5521 ccttttcatt tggctgttcc aagggtatct gccacaagtg tcagttacag gtgcagaagg
     5581 agagataagc caagtagcgt ttttgcgaat tgaccagact gcaccgtggc tatttcagcc
     5641 gatggattat ttagctggtt taagttcacc attggcgtgg ctagcaatcg gcgcaacatt
     5701 aggtgaagta agcttcaaaa aagctgcatc tgaaaaaact tcatggtatt acagtctagt
     5761 caaagtggta tttgtacctg cattgaatat cgtgattcta gcagttttga cggcaacgaa
     5821 tattctacca gtcaattttg aagcactggc aacaatcgtt atcatgatgg ctacaccagc
     5881 tgcaacagtg gcagcagcct atgctatcag ttttgatagg gaggcacttt tagcctccaa
     5941 tgcatcctta ctgtcaacta tttttgctgt ggtactgaca cctgtatgga tcgttgtatt
     6001 acaaatgatt catggcatag gtttattttc ataagaaatg gaggaagaaa gtatgagaat
     6061 cgcatgttac ggtgttcgtc cgaacgagat agattttttt gaaaaattga atatttacca
     6121 ttatgatctc agtctttatg aagaactgtt gacacatgac aatatcgtgt cagcaaagga
     6181 ccatgatgct gtattgttga ggggaaattg tatagcagat gagaccaatc ttgcaaaaat
     6241 gcaggaatat gggattcgtt atgtttttac acggactgtg ggagtcaatc atatcgatct
     6301 acaagcggca gctgattttg gtatgacagt agcccgtgta ccatcgtatt cgccaaatgc
     6361 gatagcagag ttatctttga cttttgccat gatgcttttg agaaatactg cgtatacgac
     6421 gatccgaaca tctttcaaag attttcgagt ggatgagcaa atgtttagtc gtgaaatcag
     6481 aaattgcaca gtagggatca taggaacagg caggataggg ttgacggaag ctgttttgtt
     6541 taagggacta ggagccaaag tgatcggcta cgatattcat cagacagaag ctgctaaaaa
     6601 agtattgacg ttccactcgc ttgaagagtt attagccaaa agcgatattg tcagtattca
     6661 tgtacctcat atcccaggtg aaaacgatca aatgatcaat gaaggatttt tagctcaaat
     6721 gaaaaaaggt agcatcttga ttaatacagc ccgtggagag cttcaagata atgaagctat
     6781 tttaagagct ttgaaaagca atcatttagc tggttttgca accgatgttt ttgcaaatga
     6841 aacagaggtt tttttccgat ccttcaagcc atgggagacg attccagacc ctgctatcca
     6901 gcaattagta gaaatgtacc ctagagttct tgtaaccccg catgtaggtt caaatacaga
     6961 tgaggcatta tcaaatatga tttcgacaag tttcgagaac tttcgtgaaa taatagaaac
     7021 tggaaaaacg aaaaatgagg tatctcttcc taaagcccgt caattaagat aagaaaacat
     7081 ggatattcgt caataaaatg tttaaaaata gtccaagtaa acagttgtta cttctgtata
     7141 cttggactat tttgtatggg ataattcgat gactcaacag taatctgtga gctttttccg
     7201 cccattcttt gtcaattcat aacaggttag cggccggccg atttccaaat atttgattct
     7261 ttcgttcaat atatcttgtt ctactaaaaa attcaaatat ttcttgacgg atatacgtga
     7321 cagtgagctt ttttgagcca gttcttttgt tgaaaaaata gtatcttctt ttagaataaa
     7381 tgcacttatt ttttttaaag tcagttttga cagaccttta ggcaaatcga tgaatgatgg
     7441 tatttcgtga atgggagtgg tgtggttgaa tacttgatcg atcaatttct gatcggcttt
     7501 ttcagtcgtt tggattgtct gagagaaagc aagatacttt tcgatcgcca gctgaaaacg
     7561 ttgcaaagtg aacggtttga tcaaataatc taaggcaccg tagcggatca cattctttat
     7621 ggtttcgata tcatctgcag cagtgatcaa aatcactggg atatcatttc cttgctgtct
     7681 aagccaagat aaaaaatgga taccactttc gccaggcatg tatacatcaa gcagcagcag
     7741 atctgcgttt ttttgtctga aatatttttt tccttcttct acatttctga aactttcgat
     7801 tacgttcata ttagggatgc tttccacaaa agtacgattc aattctgcaa ccattggatc
     7861 atcttcgatt atcaggacat ttgtcatcat tttgatcttc cttttttggt aattctagat
     7921 agacgattgt accgccattt gtttgtttgg aaaattctaa aaatccaccg tggcgtttga
     7981 cgattgaatg gatgagattc aatccaaacc cacgattgat tcccttcgtc gaaaaaccta
     8041 gcgtaaatat tttttctgag atttcttctg atatcccgac accgtcatcg cagacggtca
     8101 cgatgaatac ttcagcttct gtgtcatagt ttaaatgaat ccggacctgt ccgtttcttt
     8161 catgtttttg tagcacggct tcttttgcat tatcaagtaa gttccctaac acttgcaaaa
     8221 gtgaatggat ggagtcatcc atctccattt tagggataaa agaatcgctt tctaacagca
     8281 tttcaacaga ttgttctttg gcttcgttta ttttgcctaa taaaaaaccg gcaattgcag
     8341 gtactttgat cagacttgag acttggccaa tctctttttt ataattttga tttagctgct
     8401 ggataaaatg ggtgacttct tcatacttct tcaaatcaat caaaccagaa atgacatgaa
     8461 gtttattcat gaattcatgg gtttgagctc tcatggagtt tatatattgt ttcgtccccc
     8521 caagctcctc cattaatttc attacttctg atcgatttcg taaagttgcg actgctccta
     8581 aaaaacggtc attgctaaaa agaggtgtaa cgctagaaat agtttctatc ccatttaaat
     8641 acatggattg agtccgaacg gtcgtttgat gctcaatcgt ctctttaaac aaaacgtcat
     8701 atagattatc actgattttt ttcctacttc gaaatccaat agctgctctg tttggtagaa
     8761 aatgtttttt gcaggtgtat tgatcaagag gatagtttta tcagaagaga tggctaagat
     8821 tccttcatct acttcatttt cgataatcgt tttttcactt aactgttctg ctatttcttg
     8881 tggttcaagt ccaagcagta cttttttcat tttttgggca agaaaaacgg cgcctatgat
     8941 gcctacgcta agtccaataa tcaatgaaaa aacaatcatt ttttgtccat ctttgacttg
     9001 attgtcaatc gtgttgtttg ttaagccaac acaaactgca ccaataatct cttgatcata
     9061 ataaataggg acgaaatagc ggaagccgaa ccctaacatt ccttcttttt cagagaaaaa
     9121 ttcttgtcct ccaatcactt ttttcacatc ttcatgactt gagaaaggaa gaccgatgta
     9181 acttgggtct gcgtgagaat atcgaatgcc ttcagggtcc atgacaacga taaaatctaa
     9241 attcgatgca atcatgattt catttgttat tccttgaatc gcatgtgtcg ggtcaccagt
     9301 ctgcagcttt ttttggatga gtttatcatt ggcaacgatt ttagcaatgc tagagatttt
     9361 atctgacaca ctagatcggt tcatcgaaag aataaaattc ctgatcaata tggcagaaac
     9421 aatcaaagaa acgaatgtgg agaaacaaac gacaaggatg atcgtgttct ggagctttaa
     9481 tggttttttc ttaaaaaaag gaaacatagg ctacctcgaa agaatttatt gtgaaaattt
     9541 taacatgaaa acaaaaattt aacaaattgt caacgataaa cacaaccttc ctataaaaaa
     9601 caccactgag tcggtaaaag aagctataca gaattttcaa acattggtat gatagacgta
     9661 gaaatggaag gaggcgtgta tatgataggg ggaatcgcac ttgagacgat ttattggtat
     9721 acattgctga tttgtgcagg attggcagtc ctattgatta tttttggaga tgtattcgat
     9781 tttgatggcc cgcttgatcc gatgcttatt atcccttggt taactttcac aagcttattt
     9841 ggttttctag gtgagcgttt aacagatcaa tcatctttat ttttatttat tgctagtgga
     9901 ggcatatcga tagtgttggt atttttgctt aatttctata tattgatgcc gatgaaacat
     9961 gccgaatcaa cgatgtcgtc ttctgaaaaa actctggaag gacaagtagc tgttgtgatc
    10021 acaccgatcc ctgtacgagg tatgggagaa attcagttga aaagtgttac cggttccatt
    10081 agtcgtccag cttgttttta cagcccccaa gaacagacag ctgagcgggg aacgaaagta
    10141 ttgatcattg agatcaggga aagaatctgt tatgtcatgc cttatgaaag catgataaaa
    10201 gcttaaagga gcgtgtgtta aatggaaata ccagttgttt ttatcgcgat cgcaatcgca
    10261 gctttgattt tactgatgtt gctgatcgtc tttgtagcga agtaccagac agcaaaaccg
    10321 gatgaagcgt tgatcatcag tggaagttat ttaggaagca aaaatgtgca cattgatgaa
    10381 agcaataaca aaatcaaaat tgtgcgtgga ggtggcgcat tcgtcttgcc agtttttcaa
    10441 cgttcgaatc ggatcagtct attatcgagt aaattggacg tctccacccc tgaagtgtat
    10501 acggaacaag gcgtaccggt gatgtgtgat ggtacttcga tcatcaaaat cggttcatct
    10561 gtagaagaga ttgctacagc agcagaacag tttttaggca agacaagaga agaactggaa
    10621 aatgaagcaa gagaagtatt agaaggacac ttgcgctcga ttcttggttc tatgactgta
    10681 gaagaaatct atcaaaatcg cgataagttc agtcaaagcg tacaagaagt cgcttctgta
    10741 gaccttgcaa aaatggggtt gatcatcgtt tctttcacta tcaaagaggt cagagacaaa
    10801 aacggttatc ttgactcttt agggaaacca agaatcgccc aagtcaaaag agatgcagat
    10861 atagcagaag cggaagctct aaaagaaacg cgtatcaaaa aagctcaagc agaaaaagaa
    10921 tcacaagcag ctgaattaca gcgacaaaca gagatcgcag aatcattaaa agaaaaagaa
    10981 ctgaaattag caacctacaa acaagaacaa gatgttgcta aagcaaaagc agaccaagcc
    11041 tacaatttag aaagtgcccg agcacaacaa caagtaatcg aacaggaaat gcagattaaa
    11101 atcgtagaac gtcaaaaaca aatcgaactg gaagaaaaag aaatcacacg tcgtgaaaag
    11161 caatatgatt cggaagtgaa gaaaaaagca gatgccgatc ggtacgctaa agaacaagaa
    11221 gcacaagctc aaaaagtcaa agaagtgact gaagccgaag cagaacgatt ccgtgtggaa
    11281 gcactggcag aagcggaagc caataagaca cgtttagctg gacaagcaga agccgaagca
    11341 gcactagcaa aaggaaaagc agaagccgaa gcaaaacaaa agatcgccaa tgccttcaag
    11401 gaatatggcg aagcagctgt cttgagtatg gttatcgata tgctaccgca attgatgcgc
    11461 gaagcagcac agccgctagg aaatatcgaa aaaatctctg ttgtcgatac aggaagcagt
    11521 tcaggagaaa ccagtggagc gaaccgagtg acaaattatg ccacaaattt gctttcttct
    11581 actcaagaaa cactaaaagc gacaacagga cttgacttga aggaaatcgt agagaatttg
    11641 tcgacacgtg ggactactag ccaagtaaat atgtatgaag cgccaaaaga ggcagaacaa
    11701 aactcgatga aggaagaata aagtagtaca cttcaccgtt caatcaaaaa tggaggaaga
    11761 ctttttaaag ttcttctctc cattttttta ttttattgca aaagaaaatt agtcctcgct
    11821 atttttcttt tgtttttgga tcttagcttc tatctcttgt aaatttgttc ttagcaatcg
    11881 ttctttcttt tggagttcga ccaaatcttc tgatagttct tccttctttt ctgtttcagg
    11941 aggacgaaga aagaaattga taccgattgc aatgaatgtc cctataaaag tatctagtac
    12001 acgttggata gcatacaaag cggattcgcc ttgagggatg ctcaacgcaa tcagcaacaa
    12061 cgtagctatt gcggaaatga taccggaatt attgttaata ccatctgaca cgacgatcac
    12121 aataataact agaataggaa gcaagatcaa ttctaccaaa aaatcattgt gaaaatagct
    12181 tttgacaaaa aaataaatga tagctaatgt accacctaat gtattgccga tgatcctaga
    12241 ctttccaaaa gaaacggttg tagtcaagtc ctgacgcaaa gaaaaaacag cagataatgc
    12301 agcaatcatc gggattcctc gttgagtcaa atgaaaaaac aagatacata aaaaaacagc
    12361 taaggcactt ttgatcgtac gcatacctag tcgaaaacgg ccaaattgca tagagattct
    12421 cctttttggt ctttttacta tcatacctaa acttttgtct gatagctagt ttttcattat
    12481 tcaagtataa ttaaaataaa aaagggggaa gtaaatgcgt ataggaatgc gaacagtcaa
    12541 aacagtgatc agtgtcttct tttcgatggt cacagcgggt agcttatcgc tgttgtattg
    12601 gccagctgca gggatcattg cattattaag tgtaggaaat accaagcgct ctacattgcg
    12661 tacgggcatg aatcgaatcg cagcctttat attagctacg gcaacagcac tgttcagttt
    12721 ttttgctgtt gggtatacta tttttggctt cagtcttttt ttattcctgt tcatcccgct
    12781 tgcctctcgc ttcaaattaa ccgaagggat agtagtaaat tcggttttgg tcactcatta
    12841 tttagtggag gaaaacatgt cttggcagct gatcggcaat gaagcgggat taatggcgat
    12901 tggattagta tttgctttgc ttgcaaatgt ttacatgcca gatcgtacga agcagctgaa
    12961 ggaaaaccaa atacagatcg aaaaagaatt tcgaaatatt ttgagacaaa tggcagaatt
    13021 tcttttatca gaaaataaag aagatgtgca gatcaaatgc gaacatttac tgacattcat
    13081 tcgcgaaagc caagaagatg ccagagaaca tcaagaaaac tactggctca gacagccgct
    13141 atactacgaa acttacttct ctatgagaag agcacaggcc aatgtgatta aagacatgct
    13201 ggaaaatcta gagagaatcc agcaaccagc ttattatgga aaacatatct atggtttatt
    13261 gatttatact gcagaaacat tttcagagtc aaatgatggc agacaaattt taacacgtat
    13321 tgaagaagtt tatgtattgt atcggcaaat gcctctgccg actagtcgcc ctgaattcga
    13381 ggatcgagca gaattgttcc agtttttgca gtcttttaaa agttttattg aaatcaaggc
    13441 agaattctcc caacaaaaaa tccaaaaata gaggttgtga attcagctaa tattcaggtc
    13501 aaaaagctga tttcacaacc tcttctttaa acggtgttct cctgtcaact cctcggtcac
    13561 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgctcct tgtgactcgg
    13621 agctgaacgg taggctcaca acctctttct taaacggtgt tcaaaagctt tcctctgcgg
    13681 taataagtcc agccaaacga aaaataggag gagctatttt tgtttggctg ttcttattac
    13741 ttgatgcaga acagcttttt cacaaccttt taaaattaca tatttttcca tagaacttgc
    13801 atttgatcca agatttcgat gacatctttt gtcaagaaga gagagcgatt gggcaagtca
    13861 ccttcaatca tgtgtaccat attctttatt tcgtaattca ttgcttcaga tgtattcccg
    13921 ctttcgatga attcctttgt accatctgta aataagatct ccgcacgatc agcacgcggg
    13981 taatcagcaa tcgtcacata accgttctca aaggcaacga taccgacttt tggcattttt
    14041 gcctgaaaag tcaagctgac agcagcaagt tcattttctt tgttacgcaa gatagtgacg
    14101 gattgttcgt ccacgcctgt ttcaaaagga accattgtag aggcaactac ttcaggttga
    14161 gagctcaaaa agaaacgagc gaaagataca gcatacgtac cgatatccaa cagagctcct
    14221 ccagctaatt ctggattgaa gaaccggttt ttagggtctg gttctttgta actgacgaaa
    14281 ggtgcttgga tcatttttaa agcccccagt tttcctgtat ccattattga gcgtaactgc
    14341 tgataaagtg gcatgttgaa gattgtcatc gcttctgcta agatcaaatt cttttcttct
    14401 gctaagcgca tagcgtcagc cagttctttt ttattcatcg tgatggcttt ttcacataga
    14461 acgtgtttgc ctgcttccaa tgctgccaag atatggtcga tatgctgtct atttggtaca
    14521 gcaatgtaca cgatgtcgat ttcagcatcg tctaacattt cttgatagct tccgtaagct
    14581 tttggaatat tgtaacggtg agcgaagttt tccgcttttt ctgaagttct ggaagcaact
    14641 gctgttagtt cgctcgtctc ttgattgaag ctttcggcaa actcatgtgc gatggtacca
    14701 agaccaacga ttccccattg atattttttc atctgaaaac gctccttcat agttggattg
    14761 agtttcttgt ctgtctatta ttataacaaa aatcacgaag aataaagagg agaggacttg
    14821 aaacattaaa aaaaatgaaa gcagcgattt aagaggtgct ttttgatcaa aacttaagta
    14881 gaatagttaa aaggagggga taaacgtgca tcaagtatat attgatctta ttatgagtgt
    14941 attattagaa cagtttgaaa ctgaaaaaaa ttttttagat gaatacttgc tgatcagtcc
    15001 agaacaatgg caaaaatgga aagatggcga gaaaaatctg ccatctgaag cgatgcagaa
    15061 agtaaaaaat cttttcactg attatgaatg gatgctaacg caaaagattt tgcgtcaaac
    15121 gattattttt cccgaaaaac gaaacgttgc cgttgcagag tacaagcaaa tcaaaacacg
    15181 catcgcgcaa aaatggctta gcagcaaagc agcaaaagtc gagctgatcc ctttgaaaaa
    15241 taatcagcag gctggtagat accttgactt gaaagtaagt attcaatatg atgaatgggg
    15301 ctatgatgat attttgaatt ttcgtctgcc agcagatgtt caaaaacaga tcgaaggaga
    15361 aaaaatcgaa cttctcgatt gggtgaatga aaatctggaa gaaacttacg ttcatgaggc
    15421 gaatggggaa cgtgaagaac aacgaaagga tttttcaagt gaataaattt ttaggatttg
    15481 gagcagttgt gattatgatc gcagcaatgg gctatgttat ttttagcgat gatgattcgc
    15541 atgttcaagc cggcaatcaa gcagtcgaac gaacaagcac caaaacaact gctagtaaag
    15601 aaaagaacag tcaaacaacc agcagcaagg taaaggacaa agaaacaaaa gatcgtacgt
    15661 ccaaacaatt gccagatgtt aaaacagacg attggaagct agttttggtt ggtccagatc
    15721 acaaattaga aaaagaaatt gatgagtcta ctcaattggc atcattaagt aacggatact
    15781 tgatcgacaa acgcattgct ccagaatatg aagcatttgc caaggctgct gaagcagctg
    15841 gatttccatt agtgatggtc tcagcttacc ggtctgtatc atcccaacaa caagttttcg
    15901 aacaaaatgt ccaagatgtg atgagtcgtc aaggtgtatc agaagaggag gcgacaaaga
    15961 ttactaaaga aacgattacg gagccaggat acagcgaaca ccacacaggt ctggcagtcg
    16021 atgtcgtcga tcaaaactgg tacaacagtt atccttctac tgtattggat gcaagttacg
    16081 gagatcagcc tggagctaaa tggatcgcag ataatgctgc gcagtatgga tttatcgttc
    16141 gttatccaaa aggacacgaa gatataacta agatcacata tgaaccttgg cacttacgtt
    16201 atgtcggtaa agaaaacgct gagtatatca ccaaacacca attgacgcta gaagaatatc
    16261 tgaatgaatt aaatgaaaag taggaattga tcatggcgaa aaaaaagtgg aaaaagcaaa
    16321 agcgcaagaa tatccgttgg ccagcagtgg ttgccggtgt agcagtgata ctcttagcct
    16381 ttgttttttc cttgaagaat ctgtcttctc cttttactga taatcagcaa gaaaatgaag
    16441 cgcaatccca tcagcaattt attgaacggc ttgttccgca tgcccaagaa ctacaagatg
    16501 gttatggagt gcttcctagt atcattttag gacaagctat attagaatca aattggggaa
    16561 aaagtacctt ggctagcaaa tacaataatc ttttcgggat caaggcttat ggggatcaga
    16621 agaaagtaag cctggaaaca aaggaatttg ttaacgaaga atggataact atccaaggag
    16681 acttcaaagt gtatgattca tgggaacagt ccatggatga ccatacacaa ctgttcgtcc
    16741 aaggagtaga ttggaatcct gcgctgtatg aaaaagtgat tacggccacc aactatcagg
    16801 aagccgcaca agcattgcaa gatgcaggtt atgcgacaga ccccggttat gcgcaaaaaa
    16861 tcatccaggt catcgagacg tatcaattga atcagtatga ccggagatag caaaggagaa
    16921 gtggctgatg gcagaacaat ttacgccaga aatcatgacg gaattgagaa aagatatcgt
    16981 aagagtaccg gaaatcattt tagaagcaag cgggatcaag atatttggaa aattgatccg
    17041 ttcgatcatc tttactacgg atattgcgat catacgtaat acaaatgcga atgcagtaat
    17101 tgctgtgtat ccttttacac ctcatccagc gattactaaa agcattattg aggcagctga
    17161 cattccagtt ttctccggtg taggtggtgg tttgacacaa ggtgctcgtt cttcctacat
    17221 gagcatgttc gcagaagcgc aaggttcgtt aggggtcgtt ttgaacggtc ctacgccttt
    17281 agagacagta aaagaagttt gtcgagtagt tgatattcca gttatcagta cggtaacgtc
    17341 gaaatataca gaaatagatg aaaagttagc agctggtatt tcgattatca atatcagtgc
    17401 aggtaaagaa actgcagaag cagtacgcca ttttcgtaaa aaatatcctg aacttcctat
    17461 cattgcgaca ggtggtccaa cggaagaaag tattgctgag accattcaag caggagcaaa
    17521 tgccatcaca tatacgccac caagtagcgg agagcttttt agtcgtaaaa tggaaaaata
    17581 tcgggaaact gagaaaaaga atcatgaata acaggtgaga atcaaaagac gaggaagagc
    17641 agatagtggc tcttcctcgt cttttgtact ccagtactat ttgttcagaa ttcaaaaaaa
    17701 agagaaattt ttttgttttt ttacctgtaa tgtacataag aagagttaaa accttttgtt
    17761 attattagca ttctaacaaa aaaatgtctt gatttattga agcgctttct atagaatgaa
    17821 aaacgaataa aaactaaaaa aggcacccga caatttagta gcagctaaat tgtcggggct
    17881 tgaaaagtca gcgggaactg accaatcaag ttgccatagt caatgcttgt gcatcgacgt
    17941 gtatattgta cctaatttca tacagaatta ctagttattt ttctgttttt tagggaagag
    18001 cgcacacgaa gaagcatgct tatttagcta tgtcaaggat attgggcagt tgtctgatat
    18061 ccttttttct ttgcgtaatt atcctcccat cattgaagca agaagtgttt ttagcgatga
    18121 aagaagaatc agcactatct aatttttctt gaaagtattg agttgttcat cctaggcaga
    18181 acgataaggc aagtcttggt ttttattccc cttgaaaaag atcgtttaat aaatatgttc
    18241 tgtataaaaa tacagtatat tgaaaaataa caatggaagt agaggtgcag agaatgaaga
    18301 aaagaatgag aatcatctta gctttaagtg ttatgttatt cttcttgacg gcttgtgggc
    18361 aagaagatga caaaaaaatc acgctgaaca tggcttggtg gggttcgcaa gtccgacacg
    18421 atgcaacagt aaaagtaatc gagctttatg aagaaaaaaa tccccatgtg acgatcgatt
    18481 atgaatttta tgattatgaa ggatattaca caaaattagg tacactagca gcatcagatg
    18541 atatctggga cattttccaa ctgaacaatc aatttcctca atacatcaat cagattgaac
    18601 cattagatga atatgtggag caagggataa ttgatatttc taatgcagat gaatcctatt
    18661 tagcaacgac gacttacgac gggcaattag ttggactgtc taacggggtg aattcgtttg
    18721 cgattgctta caataaaaat atatttgaac aattaaatat ccctgaacca gcttcaaatt
    18781 ggacatggga tgaatttgaa caaatcagct atcaaatcac tgaagaatta ggaatctatg
    18841 ctatttcaag attcgaagat tttatagctg gctgtattat tcaaatacca caagttgaga
    18901 aaggattgaa tttttataat cgggaagatc tatctaacag cttgggattt gaaaatccag
    18961 actatctaac agattttttc cagctgcgta aaaatctggt agacaaaggg gcccatccag
    19021 aaccaggtgg tggagctgca agtacgacgg atctgtcttt tcaggcggtt agggatagag
    19081 aagcggcaat ggtgtttcta tcaagtaacc agttgacaga aatattgtca ggggctcctg
    19141 aagatatgga gattcagttg attaatccac ctcgcagaaa agcagatgga gaatctggta
    19201 tccctttacg ttcttcgcaa atgctgagta tggcaaaaag ctcagcccat aaagaagaag
    19261 ctgctaagtt tattgatttc tttcaaaaca gtgaagaagc caatgaaatt ttaaaaggag
    19321 aacgtggtgt accaatcatg tcgaatattc gagaacagct cgctcgtgca gatgatgcaa
    19381 ctttgcaagc gacatttgat tatttagaaa tgatttccga tatggacaac ggcgaagtga
    19441 atgtctttga tagtgctttg aatccggaaa ttcaagacca atacaatctt ttagttgaaa
    19501 aagtcattta tgaagaagta acagcagaag aagcagcaga gagtctttat gagtttgcgt
    19561 caaacattct aggatagcag caggaggaag gcatgaaaaa agaaaaacta aaacggttct
    19621 tggatcaaga caatgtggtc ggttacgtat ttgcttctcc attcatccta ggatttctat
    19681 tgataacagt gataccgatg atcttgtcac tttattattc gttcaccgat tatcgtttgg
    19741 gaaatccagt ctcatggatc ggcttggata attatataaa gatgctgagt gatgcccgtt
    19801 ttttgaactc catccgagtc acttttctct atgtatttgc atctgtacct gtgaaactga
    19861 tctttggtct attgattgct tatcttttaa cgaggaatat caaaggaacg actttctttc
    19921 gttctttgta ttatgtgcct agtttgatcg gtggcagtat ttctatcgct ctagtttggc
    19981 gggagttgtt ttctaaaaac gggttagtga atattttcct ggaacgatta ggcgcacctg
    20041 cgctttcctg gtttagcgat caaaaactgg tcatgatccc tcttgttttg atgtctgctt
    20101 ggcaattcgg ttcggcaatg atcatctttg ctgcaggtat caaagagatc ccaggctcgt
    20161 attatgaagc ggcagagatc gatggagcga acaaatggca gacgttttac aagatcacgt
    20221 tacctcttct ttcgccgatc attttgtata acttggttat gcagacaatc gcggcgttta
    20281 tgacttttac gcaggcattt atcattaccc aaggtggtcc gaatgatgcc acgaactttt
    20341 atgctcttta tgtgtataac caagcttttt cttttaattc tatggggtat gctagtgcta
    20401 tttcgtggat catgctgttg attatgggag ctgtcacctt tctgattttc aaatcatcaa
    20461 aaaaatgggt cgttgtgtga atgagaggag gaagaaatga ataatacagt aacgaaatgg
    20521 tttcaatacg gttttatttt gctattaggt ctagtcatga tttatccggt cttatggatg
    20581 atcgcaggtt cttttaaaac ggatcaagag attatgagtg gttcgctgaa tttgattcca
    20641 gagacttttc aatgggaaaa ttacgcaaaa ggatgggcgg ggtttgctgg aatttcattt
    20701 tttactttct ttaggaattc gtttgtcatc tctgcagttt cgacgatagg gacagttctg
    20761 agctcgactt gtattgctta cgcattatcg agaatcgatt tcaaaggaaa aagattctgg
    20821 ttcgtcgtca tgttagtaac gatgatgatt cctgcacaag tgattttgat tccgcagttt
    20881 attatttaca atcggctgaa tttggttggg acgtatgtgc cgctgatttt accacatttt
    20941 tttggacaag catttttcat ttaccagatc atgcaattca tggtcagcat ccccaaagag
    21001 ttagatgaat cagcgattat tgacggatgc agcaagtata gtgtctttac caaaattatt
    21061 tttcctttgc tgaaaccttc gatcatcacg acgatcatca tccagtttta ttggaaatgg
    21121 gacgacttca tgggaccatt gatttattta aacaagccga gatcttacac ggtatcgatt
    21181 gccatcaaat tatttgcaga cgctggatct agtacgactt acgcgagtat gtttgcgatg
    21241 tctacgttgt cgctgctacc ggtttttctg attttcttat tcttcaataa atatcttgtc
    21301 caggggatca gtacaagcgg tctgaagggc tgaatatgaa aaagccaata gaagagatgt
    21361 ttctttacaa gctcaactac tatgtctgtc ggattttttt aaccagtctt atcagtaatg
    21421 ctcttttcgc tttagttcta ggatgtttgt tcactttagg attagtgctg tctgctcgtg
    21481 ttgtctatct gatttatttt ttgatgatgt atccttctta ttatctatct gtccattact
    21541 tggcagaaaa aaaggtatgt tggaggaaag gaaaaatcaa acggatgtgt ttcatcatta
    21601 cgttgtttca gctgtttgtc attatttttg cagttgattg gtatttatta gtgggaaaga
    21661 ttggagcttg gtatctgatt ccttttctat tgtgtctgtt gctttttgta tcccatagtt
    21721 tttttagtac gctaattgat atctgcaaag aagataaagc agatagtctt gtttatttga
    21781 tcaaaaggaa tatctggctg ttgtcaaaaa acgtcaaggg gtttctgtgg tatttatgcc
    21841 ttttgtatgg actgttctgg tgtatacagc atgatttttt actcactgca ttactgtatc
    21901 cagggctgcc atttgtcaca gtattttgct taaaagaaaa ggagaatgac tttaaatgaa
    21961 gaaaaaatat gtacaagtcg gacttggtgg gagagcgcgt tttttttatg aggcaattgc
    22021 ctctacgtat catcaaactt gtgaactagt cggtttttgt gatgtatctc aaacaaggat
    22081 ggattatgca aatcggatac ttgtgaacaa gtatggacag aaaaaagtaa agacatgtat
    22141 gccatcacaa tttgagcaac tactggatga cgtacggccg gctgaagtca ttattacgtc
    22201 agtagatcga acgcatcatg attatatcat tcgtgcaatg aaaaaaggat atgatgttat
    22261 ttgcgaaaaa cctctgacta tcgatgagga aaaagctcaa gaaataataa cggtccaaaa
    22321 acagacggga agaagcctgc gagtcacttt taattatcgt tatgcaccgt atcacacgaa
    22381 gataaaggaa ctgatagaaa gtgatgtgat tggtgatgtg ttttctatcc acttcgaatg
    22441 gctgttaaat acgcaacacg gggcagatta tttcagaaga tggcatcgaa ataagcacaa
    22501 tagcggcggg cttcttgttc ataaatctac ccatcatttt gatctagtga atttttggtt
    22561 gaacagccgt ccccaaaagg tatttgcatt cggtggatta aacttttatg ggatgcataa
    22621 tgcggagaaa cgcggagtag aaatatttta cagtcgatgc tatggaagcg aactagctaa
    22681 agctgatcca tttgctatag acctgtcagc caatgaggaa ttgcgagaaa tgtatttaga
    22741 agcagaaaaa gacagtggat atattcgtga ccgcagtgta ttttccgatg atatctctat
    22801 tgaagataca ctaggcgtaa cggtcaaata tgaaactggt gcgattttga cgtattcgct
    22861 aaacgcgtat atgccgtggg aaggattcaa tgtttctttc aatggcagca aaggacggat
    22921 cgaaatgaaa gtgatcgaaa agtcttacat caatgcaggt ggagataaaa aggatgaagg
    22981 agcagccgtt cttcagtcca tccatgtcta tccgatgttc ggtgagccat atgaggtaat
    23041 cgtcgaacaa gaagcgggcg gacatggcgg aggagatccg cgtttattag atgatctatt
    23101 tggtgaagaa aaagaagaag atccgtggaa tcgggcagca actcacgtag atggtatttt
    23161 gtcgattttg acaggaatcg cagcaaatca ttctattgct tcaggaaaag cagtagtgat
    23221 tgacgagctt gtcagcttaa aagaataaga atagatttac ggaaattact tcccgtagtt
    23281 tataaaatct tgccttattg ccgataggct gtcttttgaa cactatttat tcggaaaaag
    23341 gggctatgac atgctttttg tcatgccttc tttttatgtg ggctgctttt ttagatagga
    23401 gaaaataaaa ataactattt aaacccgaac aaaaaggaat aatgcattaa aaatcattag
    23461 attttacaaa aaaataagta aaccacgttg tcagtttcag aaagtagtgt tagactgttt
    23521 tcaatatttg aaacaacatt ttttattcaa atatggcaaa ctgccttcac gtgcaaaaca
    23581 gttgcaagaa aatgaattta cactattatt agttttacat acctacttat atatcgtcat
    23641 aatatggatg acagtttcta gccagtaccg taaatgctgg actataagta aaagattggc
    23701 tatttcaccc ttcttttctt atgataaagt ggagggtgtt tttctttaac agaaacatag
    23761 taggtttttg cacaaaagcg gttatttcgg tattaataaa tgataaagga gcaaataaag
    23821 tgaaagaatt agttgaacgt attcaaaaag acggacgtat attaggcgag ggcgtattaa
    23881 aagtcgacag cttcgtcact caccaagtag accctgtatt gatggaacaa atgggaaaac
    23941 ggtttgcaga agtatttaaa gaacaaggaa tcacgaaagt tgtgaccatt gaagcttctg
    24001 ggatcgcacc agctttattt gctgcaagag aattagatgt tccaatgatc ttcgctagaa
    24061 aagcaaaaag tttgacgatg gatgaagaat tattgacagc ttctgtttat tcttttacga
    24121 aacaagtgac aagtacgatt tctatttctc gtaaattttt atcttcagaa gacaaagtat
    24181 tgattatcga cgatttcttg gcaaacggac aagcggcaaa aggattgatc gaattatgcc
    24241 agcaagctgg agcgcaagta gaaggaatcg ggatcgtcat cgaaaagtct ttccaagatg
    24301 gacgtcagtt acttgaagaa atgggattga gagtcgtttc tcttgcgcgt attgcttcct
    24361 tgacgaatgg acaagttgag tttcttgagg aggacgcata atcgtggaaa aagaaacaca
    24421 aaatggaaaa gctgcggttt tagggctgca gcatctgcta gcgatgtatg caggagcagt
    24481 agcggtgcct cttttgatcg gtacaggact aggctttaat caagaacaga tgacttattt
    24541 gatttcaatt gatatcttta tgtgtggatt agcgacatta ttgcaattga cagttaaccg
    24601 atttttcgga attggcttgc ctgtcgtttt aggatgtgcg atccaagcag tagctccact
    24661 gatcttgatc ggaaccaatg aaggagtagg agctatctac ggatctatta tcgcttctgg
    24721 gatctttgtt gtgttagttt ctggtgtctt ttctaaaatt aaaaaactat tccctcctat
    24781 agtaacagga acggttatca ccgttattgg tttgactttg attcctgtag caatcgagaa
    24841 aatgggtgga ggtaatgcaa cagcagctga ttttggtgac aaaacaaatc tgctacttgc
    24901 atttgtgacg attctcctaa ttgtaggcgt gcaaatgctg gcaaaagggt tcattcgttc
    24961 aatcgcggta ttgattggtt tagtcggagg aagcatctta gctgctttca tgggaatgat
    25021 tgatctgagc gcgattggag atgcgccgtt gttccatgtt ccacaaccct tttattttgg
    25081 taaaccaact ttcgacgtat ggtcgatttt actaatgatc atcatttcca tggtcagcat
    25141 ggtagaatca acaggtgtat attttgcact tggtgacatt actgggaaaa atgttggaga
    25201 agaagaattg aaaaagggat atcgtgcaga aggacttgcc gttatcttag gcggtatttt
    25261 caatacattc ccttatactg gcttttctca aaatgtcgga ttggttcaac tttcgggaat
    25321 caaaacaaga aaacccatct atttctctgc attcttcttg attgttttag gattattccc
    25381 taaaatcggt gcgttagcac aaatcatccc tgagccggta cttggtggag gaatgttagt
    25441 catgttcggg atggtggcag tccaaggaat ccgtatgctg ttggaagttg atttcagcaa
    25501 tgataaaaat ctattgattg ttgctgtttc tgttggattt gggctgggtt tcaatgttac
    25561 gccgacatta ttcagtcaaa tgccgcaaac attgcaaatg ttcactggaa atggcatcgt
    25621 aatgagtagc attacggcta tcatattgaa tttgatcttt aatggattga aaaaagatga
    25681 agaaatattg gaagaagcct tcaagaagta atagagcaaa agaaaggttg tgaaatcagc
    25741 gttttgacct gattgttaga gaaacaaacg gaaaaatagt tcctcgtatt ttgccgtttg
    25801 tttgagctaa taccgagggt cagctgattg aacaccgttg aaggaagagg tcgtgagcct
    25861 gccgttcatc tccgagtcac aaggaacaat ttcaaaaaaa agcttctcat gtttgttgaa
    25921 tattgttcct tgtgaccgag gagttggcag gagaacaccg tttatccata aaaaggaatg
    25981 tgacctaact tttgtcacat tccttttttt tatctttaat aaacacgaac aataaaatgt
    26041 ttttctttgt taacattcga aatttctttg acatcaaaaa aagtgattgt taaaatatga
    26101 atgtagaaaa actgggagga aaaacaatga cagcaaaaat ctctgtgatt atggggagta
    26161 cttcagattg ggaaacaatg aaagaagcat gtcaaatatt ggatgaattc ggtgtgtctt
    26221 atgaaaaaaa ggtcgtttct gctcatcgaa ccccagattt gatgtttgaa tatgcacaaa
    26281 acgctcgaaa aaaaggaatc aaaatcatta ttgcaggagc agggggagcc gcgcatctgc
    26341 cgggtatggt cgcatcaaaa acaactttgc cggttatcgg tgtaccggtc caatcacgaa
    26401 cattaaatgg tttggattcg cttctttcga ttgtccaaat gcctggagga gtacctgtag
    26461 ctactacagc aatcggaaaa gcgggagcaa ttaatgctgg actacttgcg atacagatgc
    26521 tttccatgta tgatttagaa ttggaggcta aattggctga aagacgttca atgttggcta
    26581 aaactgttat agaaagtagt gatcaacttg gttaaacctt tgttgcctgg ttcaacgatc
    26641 gggatcgtcg gtggcggtca attaggtcgt atgatggcga ttagtgcaaa agaaatgggc
    26701 tttaaagtag gtgtgctgga tcctgtgagc gattgtccag ccgcacaagt tgcagattgg
    26761 cacattgaaa gtgtctatga tgacaccttt gcgctgaaag agcttgccag aagaacagat
    26821 gtcattacct atgaattcga aaacgtcagt gtagaggcgt taaatgcgat tttacccatg
    26881 tcatttattc ctcaagggac agacttgctt gcgattacgc aagaccgcct gttagaaaaa
    26941 tcttttttgg aaacgaataa catcgtgatt gctccttatg caacgatcgt cagtccgacg
    27001 gatatccaag atgcgattga cgggatcggc tatccttgtg ttttgaaaac cactcgaggc
    27061 ggctatgatg gcaaggggca gtatgttttg aaaagtcggg cggatctagc tcctgccatg
    27121 gaccttttaa gagaaggaac ctgtgtttta gaagcatgga tcccgtttga aaaagagatt
    27181 tcgatcatgg tggcaggaaa tggtcaagga gatttcacga cttttccggt cgtggaaaac
    27241 atccaccaca acaatattct tcatgaaacg attgctccag ccgcgattga tcaggatgtg
    27301 atcgaggagg ctgagcgtat tgcccgtgtg attgcagaag cagtgagcct ttcaggtgtt
    27361 ttaggggtag aaatgttttt aacaaaaaca ggcgggctat atgtgaatga attagctcct
    27421 cgtcctcaca attctggaca ttattctatt gaagcttgtt ctatgagtca gttcgatgcc
    27481 catattcgag gtatttgtgg ttggccatta ggagaaaaag tacgtttgat aagcaatgca
    27541 gtaatggtca atgttttggg agaacaactg ctggaaagct atcgcttgat tgagaataag
    27601 ccagactggc aattccattt ctatggaaaa aaacaagcaa aaaaaggtcg caagatggga
    27661 catatcacta tcttgacaga agacatccag caaacgctgg aagaaatcaa acaaacgaat
    27721 atttgggatt agaggagaaa aaacatgtta gaacgttata cacgccctga aatggggaat
    27781 atctggacgg aagagaacaa ataccgtgcg tggctcgaag tcgagatttt agcagatgaa
    27841 gcttgggcag aacttggtga aatcccgcaa gaagatgtga aaaaaattcg tgagcatgca
    27901 tcatttgata tcgatcggat cttggaaatc gaaaaattaa cacgccatga tgtcgttgcg
    27961 tttacacgag cggtttctga aacattggga gaagaaagaa aatgggtcca ttatggtcta
    28021 acaagtacgg atgtcgtaga tactgcttat ggctatctca tcaagcaagc aaatgatatt
    28081 ttacgggaag acttgaaacg ttttacggaa atcattggcg aaaaagcaaa agaacacaaa
    28141 tatacagtga tgatgggtcg gacacacggt gtccatgctg aaccaactac ttttggattg
    28201 aaacttgcca catggtattc agaaatgaaa cggaacatcg aacgatttga acatgcggca
    28261 aaaggagtag aagcaggaaa aatctcagga gcagtgggaa cgttcgcaaa tatcccgcca
    28321 tttattgaag agtatgtatg taaacaattg gggatccgtc cacaagaaat ttctactcaa
    28381 gttctccctc gggatctaca tgctgaatat ttctcagcga tggcgcttat tgctacaagt
    28441 attgaacgtt ttgcaacaga gatacgcgga ttgcaaaaat ccgaaacacg tgaagtagaa
    28501 gaattttttg cgaaaggtca aaaaggttct tctgctatgc cgcacaaaag gaatccgatc
    28561 ggttcagaaa atatggctgg tctagccaga gtggtgcgcg gacacatggt cactgcctat
    28621 gaaaatgtca cattatggca tgaaagagat atttctcatt cttcagcaga acgaatcatc
    28681 ttgcctgata ccacgatttt attgaattac atgttaaatc gttttggcaa tatcgttaaa
    28741 aatctaacgg tctttcctga aaacatgaag cggaatatgt ctgcaacatt tggtttgatt
    28801 tatagccagc gcgttatgct gaaattgatc gataagggaa tgacaagaga agaagcttat
    28861 gatcttgttc agccaaaaac tgcgtacgct tgggacaacc aagtgcagtt ccgcccgctg
    28921 ttagaagaag atccaaccat cacatcggta ttatctaaag aagaaataga cgatgccttt
    28981 gattatcatc atcatttgaa aaacgttgac gtgatattca aacgagtagg tttggaataa
    29041 agaagagtga gttgcaaaat tcaattaaaa tagaatagca aaaataacca aaaaagaagc
    29101 agatccgtta gcggttctgc ttcttttagt ttattatatt ttcttatcaa taataggaac
    29161 ctgattttaa aagcggctac ctctttaccg tgcctcttta catacaaaaa atagaggaat
    29221 taagcgtaaa tggcttggct attataacta aaatgctggt tatggagatg ttgcagcaag
    29281 ttttcgagaa aagcgtattc catctcttgt ccattgaata agatctggat acgataatga
    29341 tttttgaaac gcttctgttc atgaatctga ctgattgaaa gttcgccttt gtgttctgtc
    29401 tgataaagaa aagtcctttt acggcattca gcacagcgct tggttgctcg gcggattttt
    29461 cggaatgtat aaaaactagt atctttattg cataaataaa cgtctttgat cgacagcaaa
    29521 tcattatata gacaggaacg ttcttcagct gttaattctg ataaaaaaag ctgaccttgt
    29581 tttattgcat cttccatcgg caagtgcctc ctcgaaccca ttatccaaat ttttagttaa
    29641 ttctaatata ccatcattaa gtataaatgt aaacgcttgt tgatggtata agattttcgt
    29701 ttctgataaa acacgaacat taaaagaatc taatgcctta aatgtacata tttttgttga
    29761 tttataaaaa gatgattgct aaaatttaaa gtgaaaaaac gaacaaaaaa cgatgtattt
    29821 gcttttaatg taaataaaaa ggagagacgt acatggagaa gaaagaactt ttgtatgaag
    29881 gaaaagccaa aaaaatatat cttacttctg atgagaactt gatttggata gaatatttag
    29941 atcaagcaac tgcgttgaat ggcgcgagga aagaccagat aagtggaaaa ggagaattga
    30001 ataatcaaat cacaagtgca attttccgtt atctgactca aagaggaata aaaaatcatt
    30061 ttattgaaca attgtctaaa accgaacaat tagcaaaaaa agtacaaatt atccctctgg
    30121 aagtggttat ccgaaatatt gcagcaggaa gtttctcaaa acgtctaggt gttcccgaag
    30181 gtaaagaatt catcaaacca atcattgaat tctactataa ggatgaccag ttggatgatc
    30241 catttatcaa tgaagagcat atctatttct tacaacttgc aaagccggaa gaaatcagtg
    30301 agctgaaagc ccaagcgttg gctattaatg aaattttgac cgaattattt gctaaggtcg
    30361 gtttggtttt agtagatttc aagctagaat ttggccggtc gaatggacaa attttgcttg
    30421 cggatgaagt aacaccggat acttgccgat tatgggatga acgtacgaat gaacatatgg
    30481 acaaagacgt ttaccgcaga gatctaggtg atttgatccc agtctatcaa gaagtatata
    30541 accgtctatc ggaactaact gaagaaaagg agcgagtatg atgtatttcg taaaagtata
    30601 tgtaacctat aaagattcag tgttagatcc tcaaggggag gcagtaaaaa aagcagtcca
    30661 tcgtatggga tatgaaacaa tcgaagatat ccgaatagga aaatactttg agatacaact
    30721 tgctgatgca gaagaaccaa tcgatacagt gattgaaacg atttgtgaca agctgcttgc
    30781 aaatgtaaat atggaaacat accgatatga aatcaaaaaa atggaggaag tataacatga
    30841 aatttgcggt catcgttttt ccaggttcaa attgtgacgc agatatgtta tgggcagttc
    30901 gcgagatcat gggcgctgat gccgaatttg tacggcatga tgagtcctct ttagaaggat
    30961 ttgatggggt tttactgccg ggaggattct cctatggtga ctatttgaga tgcggtgcga
    31021 ttgctcggtt ttctacaatc atggaagaag tgattcgttt tgctgaagaa gggaaaccag
    31081 tattcggtac atgcaatgga ttccagatat tgacagaagc aggacttttg ccaggtgtac
    31141 tgagacgaaa tgagtctttg cattttattt gcaaaactgt accattgaaa gtcaacccca
    31201 agacggcctt tacttcagag tatgaagccg acgaaataat ctatcttcca gttgctcatg
    31261 gggaaggaaa ttatttctgt gacgaagaaa cacttcaaga actaaaaaaa aataatcaga
    31321 ttgcctttac ttataatgac aacatcaacg gcagcgtgga aaacattgca gggattacga
    31381 acaaagcagg gaatgtgtta ggaatgatgc ctcatccaga acgtgcagta gaagacttgc
    31441 taggatcaga agatgggaaa cggttctttg cttccatttt aaaaaacttc ggaaaggtga
    31501 ccgtatagat gaaaacattg aaagaaccga cagctgaaga gatcaagaaa aaaagaatct
    31561 atgccgaatg gggattgact gatgaagaat atcgaatgat cgaagaagat atcttaggaa
    31621 gaatgcctaa ttatacggaa actggactgt tttctgttat gtggagcgaa cattgttcct
    31681 ataaaaattc taaaccggtt ctacgcaaat ttcctactag tggacctcat gtgttgcaag
    31741 gccctggaga aggcgcaggc atcgtcgaca tcggtgatgg actagcagtt gtcttcaaag
    31801 cagaaagtca caatcatcct tcagccgtgg agccttatga aggagctgcg acaggagttg
    31861 gcggaatcat cagagatatt ttcagcatgg gggctcgtcc aattgcgttg ctagattcat
    31921 tgaggttcgg cgaattagat aatccaagaa cgaaatattt actagaagaa gtagttgcag
    31981 gtatcggcgg atacggcaat tgtatcggca taccgactgt aggcggcgaa attgcatttg
    32041 atccttgtta tgaaggaaac ccattagtca atgcaatgtg cgtaggtttg attgaacaca
    32101 aacatatcca gaaagggcaa gccgctggcg tcggtaattc gatcatgtat gtaggtgcaa
    32161 aaacaggtcg cgacggtatc cacggagcaa cttttgcctc agaagaattt aatcaagaag
    32221 aagaacagca acgttctgct gtacaagtag gcgatccttt tatggaaaag ctgctgcttg
    32281 aagcgtgttt ggaattaatc ttgcatcatt cggattctct aataggtata caggatatgg
    32341 gagcagcagg acttgtttca tctagtgcgg aaatggcttc aaaagctggc tcaggactta
    32401 tattgacatt agatgaagtc ccacaaagag aaactgggat gacaccttat gaaatgatgt
    32461 tatcggaatc acaagaacgg atgttgattt gtgttaaatc aggagaggaa gaaaaaatcc
    32521 aagaactatt tcagaagtat gatctagatg cagtcactat cggtaaagta acagacgacg
    32581 ggcaatatcg gctatatcat caaggagaag aagtagcaaa tctgccagtc gatgcattag
    32641 ctgaagatgc accagtttat cataaagaaa tgaaagaacc agctcgaatc gtagaatttc
    32701 agcagttagc tccttatcag ccagttatcg aagaacctgg acaagtattg cttgatctgc
    32761 tgcagcaacc gacgattgct tcaaaacgtt caatctacga aacttatgat tcacaagtac
    32821 aaaccaatac agttgtccgt ccaggaagcg atgctgctgt gatgagggtt agagggacga
    32881 ataaagcgtt agctatgacc acagactgca acgcgcgcta tctgtatttg gatccaaaaa
    32941 tcggaggaca aatagcagtg gcagaagctg ctagaaatat tattgctagc ggtggtaagc
    33001 ccttggcgat caccgactgc ctgaactatg gttctcctga taaaccagaa gttttttggg
    33061 aattatcgac ttcagctgac ggaattgctg ctgcgtgtga aacgttagga actcctgtta
    33121 tttcaggaaa tgtctcttta tataatgaaa cggatggtca agcaatctat ccaacaccaa
    33181 tgattggtat ggtcggattg attgaggatc ataaacatat cactactcag gaattcaaaa
    33241 aatcagggga tctaatctat atattaggta agacgtttgc agattttgat ggcagtgaat
    33301 tacaaaagat gcagcttgga agaatcgaag gtgtgatccg aaactttgat ctatccattg
    33361 aaaagagaaa ccaagagtta gtattgacag ccatccaaaa cggattgatt gaaagtgctc
    33421 atgactgttc agaaggtggc ttggcaattg cactggcaga atcagctttc aaacatcagc
    33481 tagggatatc tgtacagttt gaattgtcct ctgctcaatt atttgcagaa actcaatcaa
    33541 gatttgtgtt gacagtcgca ccggaaaata agacacgatt cgaagaaatg atgggagatg
    33601 ctgctgtttt agcaggtaag gtgacggatg aagcgataat cgaaatttca gcaactgacg
    33661 gtcagatcaa aatagaaact gcagtagcaa gaaagtgctg ggaggatgca atcgtatgtc
    33721 ttatgaagtg aagagtttaa atgaagaatg cgggatcttc ggtgtttggg gtcatccaga
    33781 cgccgctagt gtggcatact tcgggctcca tagtcttcag catcgaggac aagaaggtgc
    33841 aggtatcgtg tccaatgatc gaggaaagct taaggggcat cgagatttgg ggctgctttc
    33901 tgaggtattc aaagatcaaa gaaaattgca gcagttaaca ggagaagctg caatcggaca
    33961 tgtacgttat gcaacagcag gcaatggaag tgtggacaat attcagcctt ttctattcaa
    34021 atttcatgat cagtcgatcg gcttagcgca taatggtaac ttgatcaatg ctcgttccct
    34081 tagaaaagag ttagaggaaa atggggcgat cttccattct aactccgata cggagatatt
    34141 gatgcatttg atccgacgaa gtgaagaaac agatttttta aataaattaa aaagtgcttt
    34201 gaatgaagtc aaaggtggct ttgcctattt attaatgaca gaaacggcaa tgattgccgc
    34261 tttggaccca aatggttttc gtccattagc aatcggacaa atgaaaaacg gagcatacgt
    34321 gattgcctcg gaaacttgtg cattagaagt tattggggca cgttttataa gagatgtcca
    34381 gcctggtgag atagtgatca tcaatgacga aggaatccag attgattgct ttacgaagga
    34441 cacgcagctt tctatttgtt cgatggaata tatctatttt gccagaccag attcaaacat
    34501 cgcagggatc aatgtgcata ctgcacggaa aaatatggga cggaatttag cgaaagaatc
    34561 gccagtaaaa gcagatatgg tcgttggcgt acctaattct tctttgtcag ccgcaagcgg
    34621 ttatgcggaa gctagtggaa tcccttatga aatcggatta gtaaaaaatc aatacattgc
    34681 ccgaacattt atccagccaa cgcctgagct aagagagcaa ggtgttcgaa tgaaattatc
    34741 tgctgtacga ggagtagtgg aaggtaaaaa ggtgattatg gtcgatgatt caattgttcg
    34801 gggtacgaca agcagacgga tcgtccatct tttgaaagaa gcaggggcaa aagaagtcca
    34861 tgtgaggatt gcttctcctc ctttgaaata tccatgtttt tacgggattg atattcaaac
    34921 gcgtaaagaa ctcattgcgg caaatcacac gattgatgaa atcaaagaat gtatcggtgc
    34981 agattcttta ggttttttaa gtgaagaggg tctgatcgaa tcgatcggtc tggaaaaaga
    35041 tgctccgtat tcaggattgt gtatggctta tttcaacgga gattatccga cgccgttata
    35101 tgactatgaa gaaaaatatc aggaatcact aaaagaaaaa gtatcgttct tttaaaagca
    35161 gaccaagaag ggagtatatg aattcaatgg caaatgcata cgcaaaagct ggcgtagatg
    35221 tcgaagctgg atatgaagta gtagaacgga tcaagaagca tgtcaaaaaa acggaacgtt
    35281 taggtatgat gggcgctata ggaggattcg gcggttgttt tgatttatcg gtctttcaat
    35341 taaaagagcc agtccttgtc tcggggaccg atggcgtggg gacgaaatta gcagtggcaa
    35401 tcgaagcaga caaacacgat acaatcggga tcgactgcgt agcgatgtgt gtcaatgata
    35461 tcttagcaca aggcgcagag ccgttatatt tcttagacta cttagcaacg gggaaaaatg
    35521 atccgttacg tttggaaaat gtagtaaaag gtgtagcaga tggatgtgtt caaggaaata
    35581 tggcgctgat tggcggagaa acagctgaaa tgcctggtat gtactcaggt aatgattatg
    35641 atctagccgg atttgctgta gggatagctg aaaaatctca attattgaca ggagaaacga
    35701 tcaacccagg agatgtgttg cttggaatag catctagcgg gattcattca aatgggtact
    35761 ctcttgttcg caaaattttc tttgagcagc agcagttttc tttatcatca aaactgccag
    35821 aattgaaaaa aacacttggc gaagaattgc ttgagccaac gaaaatctat gtttcttcct
    35881 tgcttccgct gatcaaagaa aagaaaataa aaggagctgc acatatcact ggtggagggt
    35941 ttgtagaaaa tatcccgcga atgttaccag aatctatggc tgcacaaatc aaacttggct
    36001 catggccgat tcttccaata ttcggctgtt tacaaaaata tggtgaaatt cctgagatgg
    36061 agatgtatga aatcttcaat atgggcatcg gtatggtcct ggcagtcgaa gaatcgaaag
    36121 taaaagaaat agtacacgaa attgagcaag ctggcgaaaa agtttatgaa atcgggaaag
    36181 tgatcgccaa agaaaaacat cgtgtggtgt ttataggaga agaacgatga gaatcgctgt
    36241 ttttgcttct ggaaacggaa gcaactttca agcgctagcc gattatctat cgaaaaaagg
    36301 attggaatct tcgattgact ggttgttttg tgatcagcct gaagcatatg ttttgaaacg
    36361 tgcaactgcg ttgagtgtac cggcagattg tttttcacct aaagaatttg attcaaaaaa
    36421 agagtatgaa gaagcaattt tgcataaatt gaaagaaaaa aagatcgatt tgatcgtatt
    36481 agctggatat atgcgaatca ttggaccggt attgctgaaa aattatgata aaagaatcat
    36541 caatatccat ccgtctcttt tacctgcctt ccctggtttg catggcatac gtgatgcctt
    36601 tgaagctgga gtaaaagaaa cgggtgtcac aattcattat atcgaccaag gtgtagatac
    36661 tggaccaatc atccggcagg aaaaagtgag aattgaacag gaggacacgt tcgattcttt
    36721 agaagaaaaa atccatagag tagagcatcg aatctatcca gaagtgatta gtgaaattat
    36781 tgaaaatgga ggctatctga aatgacaaga gcattgatca gtgtatcaga taaaactggg
    36841 attgtagcat tcgcccaagg tttgattgaa caaggagtag aaatcatttc aacaggagga
    36901 acaaagcatg cgttggataa agctgggatc aaaacgcttt cgatcgaaga agtgacaggg
    36961 tttcctgaaa tgatggatgg ccgtgtcaaa acacttcatc ctaaaatcca tggtggtctt
    37021 ttaggaagac gcgatctccc tagccatatg gaggcaatgg aaacggaaaa tatccaacca
    37081 atcgactttg tttgtgtcaa tttatatcct ttcaaagaaa cgattatgaa accagatgtc
    37141 gaaatagcag aagctattga aaacattgat atcggtggtc ctagtatgct ccgtagtgca
    37201 gcaaaaaacc atgaatttgt cacctctgtt gttgatccat ctgactatga agaagtactt
    37261 tcagaattac gtcagtatgg gcatacttca ctttctttca gacaaaaact agcggcaaaa
    37321 gtctttcgtc atactgcggc atatgatgca ctgatcgctc aatacttaac ggattgggtg
    37381 gaagaaaaag aaccggaaaa attgacactt acgtatgaac gaaaacaaac gcttcgttac
    37441 ggtgaaaata gccatcaagc cgctgccttt tatcagtccg ctcttctgga aaaatattcg
    37501 atcgcagcag caaaacaact ccatgggaaa gaactttctt ataataatat ccgagatgca
    37561 gatgctgcgc tacggatcat gaaggaatat gacgagccaa cggtagtcgc cttgaaacac
    37621 atgaatcctt gtggtattgg gacagcatct acgattttag aagcgtggga agcagcgtat
    37681 gaagcagatc ctgtttcaat ctttggtggg atcatcgttt tgaatcgaga agtagatctg
    37741 ccaacagcag aacagatgca taagctgttt ctagaaatca tcattgcccc ttcttataca
    37801 caagaagctt tggaattact gcaaaaaaag aaaaacatcc gattactgac agtagacttt
    37861 gcgcaggaag aaaatcaaaa tcgagaagaa acggtctcag tcttaggtgg acttcttgta
    37921 caagatcaag atctggcaat agaaaatgaa gaagagtgga aagtcgtgac aaaacgtaag
    37981 ccgactccag cagaagcaaa agcattagtg tttgcttgga gagctgtcaa acatgtgaaa
    38041 tctaatgcga tcgtactggc aaacgaacgt cagacagtag gaatcggagc cgggcagatg
    38101 aatcgagtcg gttcagtaaa aattgcgatt gaacaagcgc aagagaaaat ggaaggtgca
    38161 gttttagcta gcgatgctta ttttccaatg gatgattcgg ttgaatatgc agccaaacat
    38221 ggtataaaag caatcattca gccaggagga agcatcaaag accaagattc tattgatatg
    38281 gcgaataaat acgatctagc aatggtcttt actgatgttc ggcattttag acattagaga
    38341 ggagtcggat aaatgaacat tttggtgatc ggtgcaggtg gtcgtgaaca tgcaataagt
    38401 aaaaaacttt tagccagtcc gaaggtggat acggtgtatt gtgcgccagg aaatccgggg
    38461 atgacaaaag atggtatcaa ttgtgtcgct atcagtgagc gagatcattc agcgttaatc
    38521 cattttgtta agaaagaggc tattgattgg agtatcgttg gtcctgaagt tcctttgtta
    38581 aatgggatcg tcgatgattt tatggcggaa ggattgaaaa tcttcggtcc gacaaaagca
    38641 gcagctctga tcgaaggttc gaaaagtttt gctaaacaat taatggatac ttatcaaatc
    38701 ccgacagcta aatccagaag ttttgaatgt tacgaaaaag cagcagcgta tatcaaagaa
    38761 aatggtgcgc caatcgtagt gaaagcggac ggcttagcag ctgggaaagg tgtagtcgtg
    38821 gctaccacag tgaaggaagc gctggatgcg gcagaacaaa tgttgaacca gcatcgattt
    38881 ggggatagta gcaaaaaaat cgtcgtagaa gagtttttgg caggagaaga attctccctt
    38941 ttggcgtttg tccgtaatac caaggtgtat ccgatggtca tttcgcaaga tcataagcgg
    39001 gcatttgata acgataaagg gccaaataca ggcggaatgg gtgcttattc accagtaccg
    39061 caaatttcaa aaaagatgat tgaaaaagct gtggaagaag ttttaaaacc agcggctttg
    39121 ggaatgaaag aactaggacg ctctttcacg ggtgttttat atgcgggttt gattgctacg
    39181 aaggaaggac caaaagtgat cgaattcaat gcgcgtttcg gtgatcctga aacgcaagtc
    39241 gttctttctc ggttgaagag tgactttgcg caagtaatcg atgatttatt agagaatcgt
    39301 acagtagagt taaagtggca gcaagaagga tacaatgtag gcgttgtggt tgcagctgcc
    39361 ggttaccccg aagaatatga gacaggaatg gttctaccag attttctgga agaagagctt
    39421 tctgtttact atgctggagt ttcctcaaat aacggcaaac tagttggagc aggaggacgt
    39481 ctttatttag tagaagcata cggtgagacg atcaaagaag cacagaaaaa aatttacacc
    39541 gcgttaatgg ataaaacgac agatggaaca ttttatcgta cagatattgg agaaaaagct
    39601 gccaatagcg aactgatcgt gaagtaaatc agctgcttcc atttataaaa aatacaacaa
    39661 acataatcgg aagcgccgat tttagtgaag ccttttcata aagagtgtgg tacacttttg
    39721 ttgtgtatat aaataaggag gagttcagat gaaaaaaatt caattaggta cttctgatca
    39781 gaaagcagct gcagtgatct taggctgtat gcgtatcaac aatgcggaag atccagtaaa
    39841 agtgattgag acagcttatg aaaacggcat tgattttttt gaccatgcag atatttatgg
    39901 aaacggtgaa tgtgaagaaa tctttgcaga tgctctagca aaaacatcaa tcaaacgaga
    39961 agatcttttt attcaaacaa aatgtggaat cgttccaggt gtgatgtttg atttttctaa
    40021 aaaacatatc attgaatctg tagaaaaaag tttgacccgt ctgaaaatgg attatgtgga
    40081 tgctttactt cttcatcgtc cagatacatt ggtagaacca gaggaagtag ctgaagcgtt
    40141 tgatgaattg gaacggtcag gaaaagttcg ttattttggc gtcagcaatc aaaaaccaat
    40201 gcaaatcgaa ttgctgaaaa aatatgttcg tcaaccatta gtagctaatc agctgcaatt
    40261 tggcttgaaa catactggaa tgatcgatca agggattcat gtcaatatga cagatgaagc
    40321 aagtatcgat catgacggta gtgtacttga ttattcccga ttgcatgata tgacgatcca
    40381 agcatggtca ccataccagt atggattttt tgaaggtgta tttatcggga acgaaaaatt
    40441 ccctgaatta aaccaaacat tagaagaact agcagctaaa tatcaaacga caccaactgg
    40501 cttggcttct gcttggattt tacgccatcc agccaatatg caagtgatcg ccggtacgat
    40561 gaacgtaggg cgaatcaagg aaatcgctca agcttcagaa attaatatgt ctcgggaaga
    40621 ttggtacgaa ttgtaccgtg ctgctggaaa cattttacct taaagattgt cataagcagg
    40681 tcaaaagggc tataaattaa aaagacagaa taacttgaaa gctgttttca gcttcgagat
    40741 attctgtctt tttttattgc aaatggaaag agtatcattg tacggatttc gtttattagt
    40801 tatttttgtt tttaaggaaa agctgtgtcc gatattcttt tggagaaatc ccttgttttt
    40861 tcttaaataa ataactgaaa tagttagggt cattataacc aatttcaaaa gcaatatctg
    40921 aaatacgata gtctgattgc tgcaataatt tttttgctaa ttcgattctt tgttctgtca
    40981 gataatcgat gaatgtttgg ttaaacgatt gagaaaaaat cgtactgaaa tgagagggac
    41041 ttaatgcaac ttgttgagcg acccaagtta aggacatatc tggatcggta aaattttctt
    41101 tgataaaatc caatgcatgg ttcaaaattg gctgatattt gttccttgaa ggctgtgagg
    41161 gcagagcagt taagaaagaa atgaacatat aaactgtcga acggtaaagc gagtcgtcgg
    41221 cgctgattgc taagcgttga ctggtggatg tgcaatgaac catttcttgc gggattttct
    41281 tttctttcag gcagacatgc tggagtagct tagtcaagac aaataaacga tataatcgtg
    41341 ttcgagttgg tgtgccttgt ggtttcgtca agtgttcgat gtacttagat acttcgtttt
    41401 tcgataatga agacaaatca agtgagaggt caaagtaaaa gacagaatca actggaagtt
    41461 tcgcttcttg aatcaaatcc tcatagctga taatttgttc tttaagggaa ctggcggttt
    41521 caagtatcat ctgcgtgatc tcaaaagatg caggtaattc gctgattctt tctgcgacag
    41581 gaccaatggc gacagaaaaa ttattttttt gtcccttttc taattcatgg accaacgttt
    41641 gggctacctg ataactggtc tcgatcacat tttcttcaag agaatcaact attaaaaatt
    41701 tgatgaatcg agaggaaaca gcagagaaga tcacttgttg attctcccta aataaaaact
    41761 tcaaataatc actgagatga gcgtaatctt caaagtctgt actgacttgg tttgctgcta
    41821 ataatacggt catttttttc cctgctaaag agcgattgaa agattcagca agtttcaatg
    41881 tttcactgat cgtaagtgag cctttgaaca aaccgttcaa gaaatgattt tttttcaatt
    41941 cgaaaacaag atcagaagaa gtgtgcgttt ctttttgctg caaatctaaa gcagttactg
    42001 ctttttctat tgcttgtttc aattcgctac ttttaatcgg tttaagcaga taatcatctg
    42061 cctgtacctg gattgctcct ttcatataat cgaaatcgtc gaatccacta ataaatatga
    42121 gacgagtcca aggaagtagt ttccttgctt cttttgaaaa agtcaacccg tccatgaaag
    42181 gcatttggat atcagtcaga atgatgtcgg gctgtaagtc gataattgaa gacagtgcca
    42241 tctcaccatc tccagcttcg ccgacataag tgattggata ataagaacca aggacagtta
    42301 tttgttcccg caagttattg cgaatgaggt attcgtcttc gatgataaaa actttataca
    42361 tgtttgtttc ctccaattgt tttgggagat agagggatca tcagtgtgac agttgttcct
    42421 tctcggtatt tgctgtcaat cgtgataggt ttttgatcat ttccgtaata aagaaggaga
    42481 cgcttgttta cgttgtaaag tccgtagccg atactgaaat ctgaatcgat ccctttggct
    42541 aactctttac gtatttctgc cagtttttct gcagggatgc caatcccgtt gtctataact
    42601 ttgaattgga tcatctcatc aattttgcat gtggtaatac gaataaatcc tttgtgacgg
    42661 acgtacttcg ttccatggta tacagcattt tcaatcaatg gctgcaagat catttttaaa
    42721 atagaaacag gaaaaagtgt ttctggtata tcgatcttat agtcaagcat atggccgtat
    42781 cttattttta agatgactag ataatcattg atatggctaa tttctttttc aagaggaatc
    42841 cagtcttgtc ctttgcttaa agacgtacga aaaaagccgg aaagtgcatg ggtcatagtc
    42901 agagcttctt caaagcagtc ttgttcgatc aaagaaataa tggcatccaa actgttataa
    42961 ataaaatggg gagtaatctg agcttgcaat acacgaactt cactttgtgc taaatggtat
    43021 tgtttcaaag cgttctcccg taaagactgg tttagatctt ccgccatttt attcatgcta
    43081 gcggtaagtg tttgtaattc cagtgtttcc ggcagggtta aacgaaagcc aaggttccct
    43141 gaagaaagtt gttctgacat ctcgatcagc tgattgatcg gttcttggac ctttctctct
    43201 aaaaagcgac gattcttttt cgcatagaaa aaaatggtac taagaactcc aagttccact
    43261 attgttaata gaatgagcga gcggacaagt gtcgtatttt ttttgcttgc taagtcgatc
    43321 tccacacgaa caaaatcttg taagatatct gacagcagtt gagtgacaga atctacctga
    43381 ttgatgatct cttcattggt atccataaaa tcttttgcca agatattatt gatcagctcg
    43441 ttttgataat cttccagtgt atcgatcgta cgtagcgata catctaacgt actaatttct
    43501 ttaagtgtat ttgtattatt tttgatctct cgaatatcat tcctaagttc ttctaggata
    43561 ttttcctcat tgaactcatc tacggttact tggccagaaa tcaagtccca catactttcc
    43621 aaaacttttt gatcaacctt caaagcaatt gcatctgctt tttggatatt tgcgatcgtc
    43681 tgttgataaa tcaaaagctg ttgcgaatat aacagtatgc tcagtagcaa agggataaca
    43741 gcaaatagaa gcatggcttt gtttgcttgg gcaaaaatct gttttatgct taaatttttt
    43801 gtcatgatac ttctccagtc aataatttct ggttgggatg ttagctatat tctgctggga
    43861 aaagacagtc tcggaaataa aaatatcttt aggtaatgtt tttcctgttt gaatatttcc
    43921 aaaataacga gtaacggtat tggctacata ccagccgaca tcaggtttac actcgactac
    43981 acaattgacg attcctgagc gtagcttctc gatcatatct tcttgtccat caatagttac
    44041 aatgatcaaa tcttctccag gtttgattga tgtttctttt atcgcagcta aagcaccgtg
    44101 agtcatttca tcactatggc tgtataatac atcgatttcg gataaatcat ttgtttctaa
    44161 atatcgtttc atctggtctt ttcctttcat ccgaataaaa tcaccgacaa ttcggtgaac
    44221 aatagtcatc ggaggtttat ggtcgatggt tccatctttt tttagggttg gtttacgatt
    44281 gattgattcc aaaaatcctt cggagcgtag cttggtcggt gtggagttct ctgaaccagc
    44341 aagttctagg attctgattt cctgtttctt tgaatttgtg aagtgattgc tgacaaataa
    44401 acccgcccga tttccttctg ctttgaaact ggggccaatg tgggtgacga aaagctcggg
    44461 atcattcgtt tgaatatgtc tgtcgacaag tatgacaggg atccctgctc gctttgcttc
    44521 ttttaataca gagtcccacc cggattcttg caaaggagta aaaatgatca tatccacttt
    44581 ataggcaatg aacgtccgta tatcttggat ttgccgttcc tgattcatgt agccatttcg
    44641 gtagagaact tggtaatctt ctttttcaag cgcagtgata attgattcag tatgcttttt
    44701 ccgccagcta ctctccgttc ctgattgcga aaaaccaacg actagtgggt caggtgcttc
    44761 ctttgtatta ggtgtacacc ccatcatttg gtaggcgatt acaacaaggg ctaaaaaaaa
    44821 taaaacacgt ttcactttaa atcactccat ctggatttgt tagtactatc ttatcagata
    44881 aaagggaaaa tcaaagtcaa aaggaatcaa tcgaaaaaaa tccaagaaac ttaaaaaaat
    44941 ccaagacaaa aaaagtacac ctaaaaaatt taaagtaaat cccataaaaa aatcaatgtt
    45001 aacgctttct ttattagcta tactcggtgt atcaattgaa atgggggata aaaaatgaaa
    45061 aacaaattta gaaagattgt tgggactatc gctattttga ccgcaagcat tctattaagt
    45121 gcgtgtggca attcaggatc tgcagatgat agtacggggt atgtaggaat cgctatgccg
    45181 accaaatcag cagaaagatg gatcgctgat gggaacaaca tggtctcgga attagaaaaa
    45241 ctgggttata aaacagatct tcaatatgga gaagataaag tagaaaatca agtagcacaa
    45301 atagaaaata tgattacaaa aggggtagat acacttgtga ttgcttctat cgatggttcg
    45361 gctttaactg atgtgttagc taaagcaaaa gaagcagata tcaaggtgat cgcctatgat
    45421 cgtttactga tgaattcaga aaatgtcgat tattacgcga cttttgataa ttttggagta
    45481 ggtgtatcgc aagcagctta tattgaagag cacttaggat tgaaagaagg aaaaggacca
    45541 ttcacgattg aattatttgg tggctcgcct gacgacaaca acgcactaat caattacaac
    45601 ggagtgatgt ctgttttaca accatatatg gacaacggtc agttggtcgt gccatctgga
    45661 cagacgagtt tcagtcaaat cgctacgctt cgctgggatg gttctacggc gcaagcaagg
    45721 atggataatc tgttaagcgc aaattatact gaccaaacat tggatgctgt tttgtcgcca
    45781 tatgatccaa taagtttagg aatcatttcg tcattaaaag gcgtggggta tgggagtgaa
    45841 agtaaacctt tacctgtgat tactggacaa gatgcgacag ttgctggcgt taaatcgatc
    45901 attgccgggg aacaaacaca aacgatcttt aaagacacac gtatcttagc aaaaaatacg
    45961 attgaaatga tcaaagcaat cagtgatgga gaagaggttc cggtcaatga tactgaaact
    46021 tatgataatg gggtgaaaac tgtccctacg tatttagcaa atacagtatc tgtcgataaa
    46081 gataattatc aagcagagct gatcgacacc gattattata aagaatccga tctgaaaaat
    46141 taagaggaac caaacaagga actaaagaga tctaagtcag agagaggata agaattatgg
    46201 cggattgtat tttaaaaatg gcagatatca ccaaaaaatt ttctggaatc cgagcgttag
    46261 attgcgtgaa tctgatgatt gaacgtgggg aaatccatgc attgtgcgga gaaaacggag
    46321 cgggaaaatc aacattgatg aatgtcttga gcggcttgta tccatatggc tcctatgacg
    46381 gggaaatctt ttatgatgga aagctgtgtc aatttaaaga tttgaaagat agtgaagaaa
    46441 aaggcatcgt catcattcat caagaattag cactaagtcc ttatctttca ataaaagaga
    46501 atatttttct cggaaatgaa caagcagaaa gaggcgtgat tgattgggaa ctgacagaaa
    46561 agaaaacata tgaactgctg aataaagtcg gtttgtctat cgacccgaat cttctagtat
    46621 cccagattgg cgtagggcaa cagcaactag ttgaaatagc taaagcatta tcaaaatccg
    46681 tccgtctgtt gattttggat gagcctaccg ctgcattgaa tgaagaagaa agcgcgaatt
    46741 tgctgagatt gatccgagag ttgaaagagc aaggtgtaac ctccatcatt atttcacata
    46801 agctgaatga aatcgtggat atcgcagatc gaatcaccat tttacgggat ggacagacga
    46861 ttgagacact agaaaatgaa atgatcagcg aagagcatat tattcgcgga atggtgggca
    46921 gagatttagt tgatcgttat cctgaaagaa aaccggatat tggagaagtt tattttaaag
    46981 tagaagactg gacggtctat caccctcttg atcacgagcg aatcataaac gaccacatca
    47041 acttgcattt gaaaaaagga gagattgtag gaatagctgg actgatggga gcgggcagaa
    47101 ctgaattcgc tatgagtcta tttggacatt cttatggaag caagatatcc ggacgtatat
    47161 taaaggaagg ggcagagata tcagttaaga ccgttccttc agccattgca aacggactcg
    47221 cttatgtctc ggaggaccga aaatctttag gactgaatct gctgatggat attcgggaaa
    47281 acgtgacgct gagcagtttg gataaaataa gtcaaaaagg agtattagat aaagaaaaag
    47341 aagtaactga ggcagaaaat ttccggaaaa agatgcgtat aaaaacaaac tccatccatc
    47401 aaattgtcag tagtcttagt ggtgggaatc aacaaaaagt cgttttatcc aagtggctga
    47461 tgacacaacc cgatattctt tttttggatg agccaacccg tgggatagat gttggggcaa
    47521 aatatgagat ctacacgatt atcgaagaaa tggcagcaaa tggcaaagct gtctgtctta
    47581 tctcttctga acttcctgaa atattaggga tgtgtgatcg aatctatacg atgaacgaag
    47641 gacgtattac aggagaagtc tcgcgagaag atgcagatca ggaagtcttg atgaaattaa
    47701 tgacgaaaga agaggtgggt taagttggaa caggcaaaaa atcttacgga taaaaaagag
    47761 aaaaaactaa atttgaaaag tagagcagct gatctttttg gtcgctacag catggtgatc
    47821 attttagcgg gactacttat tgcgtttcaa ttgatgacgg atggtatttt ctggcgtcca
    47881 ttgaatataa ctaaccttgt tctgcaaaat agccatatat tagtactagc tgcagggatg
    47941 ttattagttg tgctcttagg tcatgtggat ttgtcggtag ggtcagtgat ggcgtttgtt
    48001 ggtgcaattg cgggcatgat gatggtcaat cgccaaatga acccgtggat gacagttatc
    48061 gcatgtcttg cagtaggcgg gctgatcggc gcatggcaag gtttttgggt agcttatgca
    48121 gggataccgg cgtttatcgt gactttagca ggattgctga tgtttcgtgg actgacacaa
    48181 gttgttctag gaggccaatc tctagcacct tttccagctg ttttccaaaa aatgtctacg
    48241 ggttatttac cagacttaag cgaaggaagc agccttcact tcttgacatt gattttagga
    48301 atgatcatca cgatcgtgtt agttgttggt caatggcgaa caagaaatcg tcggaaaaat
    48361 catttatttg aagtggaatc tccaacagct ttcttggtaa aggcggtatt tacagcagtc
    48421 gttgtactag gaataactta tatctttgcc tcttatcaag ggtatccgat tattttgatc
    48481 attcttggtt tgatcgttgc agcatatggg tttttgacaa ataaaacagt agcaggtcga
    48541 cagatttatg cgacgggcgg aaatcgaaaa gcggctgaac tatcagggat caaaacaaag
    48601 cgaatcacgt tctgggtatt cgtcaacatg ggagtcatgg cagctttagc tggattagtt
    48661 ttagctgctc gattgaatgc ggcaacacct caagcaggta catcgatgga actggatgca
    48721 atggcggcag tatattttgg tggtgcttcg acttccggcg gcattggaac aatcatgggt
    48781 gcgattgtcg gtggcttggt catgggtgta ttgaacaatg gcatgtcgat tttaggcgtc
    48841 ggggtagact ggcagcaggc aatcaaagga ttgatcttgc ttttagccgt tgtgctagac
    48901 ttgtataata agaaaaaacg aacaacgtag gagaacgccg gttattcaga aaaaagactg
    48961 tgacaagaca tttgtcacag tctttttttc gctaaaagcg aacattcatt gtttcgtttg
    49021 tatagactaa aaataatata tgttttttta ccattcgtat aaattctctt tttgctcttg
    49081 atttttttgc ttaattgagt taaattacat agggcgctaa aaaaagcctt gattaaatta
    49141 ataatgttcg tgttttgctg gatgtgaaca tcaggaggat aatgtaatga aagtatttga
    49201 ttacgaagat attcaattaa ttcctaataa atgtatcgta aatagccgtt ctgaatgtga
    49261 tacaacggtc acattaggta aacatacatt caaaatgcca gtagtgcctg ccaacatgca
    49321 gacgattatt gatgaaacaa tcgcagaatt cttagcggaa aatggttatt tctatatcat
    49381 gcatcggttt gatgaagcag ctcgaattcc gtttatcaaa aaaatgaaaa agcgtggatt
    49441 gattacctcg atcagtgttg gcgtcaagaa agaggaatat tcctttatag agaagttggc
    49501 agaagaatcg ctaaatcctg attatatcac tatcgacatc gcgcatggac atgctaactc
    49561 agttattgat atgattcagc atattaaaaa atatttgcct gaaacttttg tgattgccgg
    49621 taatgttggt acaccggaag ccgtccgtga attggaaaat gcgggcgcag atgcaacaaa
    49681 agtcgggatt ggtccaggaa aagtatgtat tacaaaaatc aagacaggct ttgggactgg
    49741 aggctggcaa ctggcagctc ttagatggtg tgcgaaagca gctcgcaagc cgatcatcgc
    49801 tgacggtggg atcagaacac atggcgatat tgcaaaatct gtccgttttg gtgcgacaat
    49861 ggtcatgatt ggttcattgt ttgccggtca cgaggaatct cctggcgaaa caaaagtcga
    49921 aaatggaatc gtgtataaag aatactttgg ttctgcttca gaattccaaa aaggcgaaaa
    49981 acgaaatgtt gaaggaaaga aaatctggat ccaacacaaa ggatctttga aagatacact
    50041 agtggaaatg caacaagacc ttcaatcatc tatttcttat gctggaggaa gagatctgga
    50101 agccattcga aaagttgact atgtcatcgt gaaaaattcg atttttaatg gagacacaat
    50161 ctaaaaaata aataaaatat taggatgttg tgaaaaagtt gtcctgcatt aagtaataag
    50221 aacagccaaa caaaaatagt tctttatatg ttttgtttgg ctggaattat tatcgcagat
    50281 acaagctttt gaacatcatt attcagaata agggactgtg ataagatttt tgtcacagtc
    50341 ccttatgttt tgcaaaaaaa gtttttcttt tttctcgtaa attcggtaaa atcaaaagaa
    50401 aaaatagaca atagaaaaga gaagcttatg tgggaaaaag tagagaaaaa acaaggaccg
    50461 atttatcgtc aaattatgga acagattatg agagaaatcg aaaacggaag gatcaatcct
    50521 ggaagtcaac ttgaatcaga acgaaaacta gggcaacttt ttggtgtgaa tcgttccacc
    50581 gttgtccatg cattggaaga gcttagggag cttggggtac taacgagcaa acgtggcagc
    50641 ggatggtttg ttaatcagac tgaatggggg aaattcgctg ttccaagaat cgattggcgg
    50701 caaatgatct ctcctcgtta tgagcagacg gactggtatg agcaaaaaat aagagaagca
    50761 aagcagatcc aaaaaacatc gtttcttgat ttatacgcta gcgagatgcc agatgagctt
    50821 ttgccgaatt ttgagtttcc ttcttattct cttgaagaaa tcttagcgga agaaaaagaa
    50881 atggatcttt taggctatac tccgttacgt aacaaaatca aacggtattt ggaaagtaaa
    50941 tttgaattgg cattttcccc caaccagctt cttgtgactg gtggcggtca gcaagcaatc
    51001 tttttgattt tacaaacgat tctttcagct ggagagggga tagctgtaga gtcaccttct
    51061 tttttttacc gattacctct tttcaaagct tcaggaacgc gtttatttgg gataccgatg
    51121 gatgaagaag ggatcgactt agaaaaactg aaagaatcga tccataaaaa taaattgaaa
    51181 gcagtgctta tcaacccgaa ttttcaaaac cctacaggaa aagtgatgag tcaaaaacga
    51241 cgagaaaagc tagtagaatt gtgtcgacag tatcggcttc caattattga agacgatgta
    51301 tttacggatc tttcatttct aaaccaagaa gaagtccttc ctatacgaac gattgatccg
    51361 gataatgtgt tatacgtcgg ttcgttatct agggttttag gaaaaacaac gaaaatcggt
    51421 tgggtgatag gacctgagac ttttatctcg caactagctc aagcgcaaga aatgatggag
    51481 ttttcgatga atatccttac acaaatcaca gtggctaatg tatttaatga agcaattgat
    51541 ttgaaaatgc aagatgtaag aaaaaagttg aaagaaaaaa gccgactgat aagcgcttgg
    51601 ggagattcac aatcgttttt caagcttcat tcaattttag gtggttacta tgcctggatt
    51661 acttgggatg ggaaaaaact agaccccgaa ctagcagaaa aagtagtaga tatgggtctt
    51721 ggaattgcac caagtctact ttttgggcaa gatataaatg gaatcagaat caattacagt
    51781 aggctggatg aaaaccaaat accgttgttt tattcaaaga tgaaaattct agaaaagtgg
    51841 ttaacagaat aatttcacaa agtaaataga ttaaagaata taacagcttg gatttaaatt
    51901 tcaagctgtt tctttttttt cggaaaaaga atacgatata aagaaactaa gaaaaaacca
    51961 ttatttgtac gtccgttcac gatgtgtaaa taaaataaat gtttgcaaca aaactgtata
    52021 acaccaacgt ttttaaatag aaacagatgg ttgtaagttt gattagaaaa tagaaaaaat
    52081 gcagatgaaa tataaaacgc tttccttatt gtgattttat tcactaatgc tgttaatatg
    52141 cggattggca taatttcctt tcatcgtgaa aatttgtgct tttagcttgt atttctcata
    52201 aatccatgat aatttattaa tgaagacggt taaatagtga tacagtttta ttcactgttt
    52261 caatcgcaga atgaagagat tttcttatag atgagagagg aatgtgtgac aaatggcaaa
    52321 caaaaaagca ccgatcgact tccaagcact gctagatgaa gtcaatgcag atttcccagt
    52381 atatcaagca cttgatcaag atggaaacgt agttaacaaa gatttagtac ctgatttatc
    52441 cgatgatgaa ctcgttgaat taatgactca tatggtatgg tctcgtgtat tagaccaacg
    52501 ttcaacagcg ctgaaccgcc aaggacgcct aggctttttt gcaccaactg ctggacaaga
    52561 ggcaagtcag ctggctagtg cttacgcatt tgataaagaa gatgttcttc ttccaggtta
    52621 tcgggatgta cctcaactag taaaacatgg tttaccttta tctcaagctt ttttatggtc
    52681 tcgaggacat gctgcaggta attcttatcc ggaagaattg aaagctctac caccacaaat
    52741 tatcatcggt gcacaatatg tacaagcagc cggtgttgca ttaggtttga agaaacgaaa
    52801 caagaaaaat gtcgtcttca cttatactgg tgatggcggt tcatcacaag gtgattttta
    52861 cgaagcaatc aatttcgctg gcgcttacca tgcaaatgcc gtattttata tccaaaacaa
    52921 cgggtatgcg atctctacac ctcgtgaaaa acaaactgca gcaaaaacac ttgcacaaaa
    52981 agctgtcgca gctgggattc ctggtattca agtcgatgga atggatccgc ttgcagtata
    53041 tactgtatct aaaatggcac gggaatgggc gatcagtgga aatggaccag tcctaatcga
    53101 aacactgact tatcgttatg gaccacatac actatctggt gacgatccaa cccgctaccg
    53161 tacaaaagac acagatgacg attggcagaa aaaagatcca ttgatccgct tccgtaaata
    53221 tttgacggaa aaaggacttt ggtctgaaga aaaagaagaa caagtcatcg aagcaactaa
    53281 agaagaaatc aaagcagcta ttgctgaagc cgacaaagta ccaaaacaaa aggtttcaga
    53341 tttcttgaaa aacatgttcg aagtatctcc acaatcaatc aaagaacaaa ttgcaattta
    53401 tgaagcgaag gagtcgaaat aatcatggca caaaaaacaa tgatccaagc aatcacagat
    53461 gccttagcac ttgaactaga aaatgacgag aatgtcgttg tttttggtga agatgttggg
    53521 aaaaacggag gagttttccg ggcaactgaa ggattgcagg aaaagttcgg agaagaccga
    53581 gtattcgata ctcctttagc tgaatctgga atcgcaggat tgagtttcgg tcttgcgtta
    53641 gaaggatttc gtccagttcc tgaaatccaa ttctttggtt ttattttcga agcaatggac
    53701 gaagtagtag ctcaaatggc tcgtacaaga tatcgaatga gcggcactag aaatctaccc
    53761 atcacaattc gttcgccatt tggtggcggt gttcatacac cagaattgca ttcggataat
    53821 ttagaaggtt tgatcgctca gtctcctggt attcgagtag tgattccttc caacccttat
    53881 gatgcaaaag gactattgat ttcttctatt agaagtaacg atccggttgt tttcctagaa
    53941 cacatgaaac tatatcgctc attccgagaa gaagtgccgg atgaagctta cgaagttcct
    54001 ttggataaag cagcagttac tcgtgaggga acagatgtat ctattatcac atacggagca
    54061 atggtgcgtg aagcaatcaa agcagcagac aatcttgcaa aagaaaatat atctgttgaa
    54121 atcattgatc ttcgtacagt tgcgccatta gatgtagaaa cgatcattca atccgtggaa
    54181 aaaactggtc gcgtagttgt tgtccaagaa gcacaacgac aagcgggcgt tgccgcgcaa
    54241 gtagtttctg agatctcaga acgcgctatc ctttcattag aagccccaat cggacgagtt
    54301 tctgcacctg atacagtctt cccatttgga caagcagaaa atgtctggtt gccaaatgca
    54361 aaagatatcg aagacaaagt aaaagaaatc gcggaatttt aagaaaagaa gggacgaaac
    54421 aaagtcatgg cttatcaatt taaattgccg gatatcggtg aaggaatcgc agaaggtgaa
    54481 atcgtcaaat ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa
    54541 gttcaaaatg acaaatcagt agaagaaatc ccgtcacctg ttacaggaac ggttaaaaat
    54601 gtgattgttc cagaaggtac cgtagcaaat gttggggatg tattagtaga aatcgatgca
    54661 ccaggacacg aagacaatga aggggacagt ggtgtagccg cagaatccca aactccagct
    54721 aaaccggctg ctgaacccac tgttgataca gaatcagctg gatcgtcaag cgaaggagtc
    54781 ttccaattta agttaccgga tatcggtgaa ggaatcgcag aaggtgaaat cgtcaaatgg
    54841 ttcgtcaaac caggagatac gatcaatgaa gatgatacat tactagaagt tcaaaatgac
    54901 aaatcagtag aagaaattcc gtcacctgtc acagggacag ttaaaaacgt gattgttcca
    54961 gaaggcactg tagcaaatgt tggggatgta ttagtagaaa tcgatgctcc tggacacaat
    55021 agtgcaccgt caactagtgc gccatcagct gaagcaccaa aagaaaaagt ggaaacatca
    55081 ggttcagcaa gtgtcgttga agctgccgat ccaaataaac gtgtattggc tatgccatct
    55141 gttcgtcaat ttgcccgtga aaaagatgta gatatctcac aagtaactgc aactggaaaa
    55201 ggtggcagag taacaaaaga ggacatcgaa aacttcttgg caggtggtcc aagcagtgca
    55261 ccagcgaaat cagaagcgcc agaagcggca gcaccgaaag aagcagctcc tgcagcagaa
    55321 agcaaaccag ctgcaccagc aaaaccattc aagtccaact taggagactt ggaagaacgt
    55381 gtagcaatga cgccaacacg taaagctatc gctaaagcaa tggtcaacag taagcataca
    55441 gctccacacg tgacattgca tgatgaagta gaagtgtcta aactatggga taatcggaaa
    55501 cgatttaaag aagttgctgc tgcaaatggt acgaaactta ctttcttgcc atatgtcgtg
    55561 aaagctttaa cagcgactgt taagaaatac ccagtattga atgcatctat cgacgatgca
    55621 aaccaagaaa tcgtttataa acattactac aatatcggta ttgcaactga tacggatcac
    55681 ggactatatg taccaaatgt gaaagatgca gaccgcaaag gaatgtttgc tattgcagac
    55741 gaaatcaatg agaaagcaaa attagctcat gacggcaaac tatctgcaga agatatgcgc
    55801 aatggaacaa ttacgatcag caatatcgga tctgtaggtg gcggttggtt tacaccagtc
    55861 atcaactatc cagaagtagc tattttaggt gtaggaacga ttgcacaaca accaatcgta
    55921 aatgctgaag gcgaaatcgt tgtcggtcgt gtgatgaaac tgtcattaag tttcgatcac
    55981 cgtatcgtag atggagcaac tgcgcaacaa gcaatgaata atatcaaacg tcttttagct
    56041 gatccagagc tattaatgat ggaaggatga taaacaaatg gtagttggag attttgctgt
    56101 agaattagat acagttgtaa ttggtgcggg acctggtggc tatgtagctg ccatccgcgc
    56161 tgctgaaatg ggacaaaaag tagcaatcat tgaaagagag tatattggcg gtgtttgttt
    56221 gaatgtcggc tgtattcctt caaaagcact gatagctgca ggacaccatt atcaagagtc
    56281 actagattct gaaatgtttg gagtaactag tgaaaacgtc aaactagatt ttgcaaaaac
    56341 acaagaatgg aaagaaaaca aagttgtcca tacgttgact tctggtgttg gtttcctatt
    56401 aaaaaaacat aaggttgaaa caatcgaagg agaagcgttc ttcgtagatg atcacacact
    56461 acgcgtcatt catccagatt cagctcaaac ttattcgttc aataacgcaa tcatcgcaac
    56521 aggttcccgt ccaatcgaga ttccaggatt taaattcgga ggacgtgtgt tagattctac
    56581 tggcggatta gcattgaaag aagtacctaa gaaatttgtg atcatcggtg gcggtgtgat
    56641 tggtgccgaa ttgggcggag cgtacgcaaa cttaggagca gaagtaacga ttcttgaagg
    56701 ctcaccacaa attttaccaa cttacgaaaa agatctagta aaattagtag aagatgattt
    56761 caagaaaaaa ggcgtaacag tcgtaacgaa tgcaatggcg aaagaagcag tcgataacgg
    56821 tgacagcgtg acagtgaaat atgcagtgga cgggaaagaa gaatccgtta ctgctgatta
    56881 tgtgatggtc actgtaggtc gtcgtccgaa tacagatgat atgggcttag aacaagcggg
    56941 tgtcgaagta ggagaacgag gattgatcac ggtggataaa caaggacgta cgaacgtacc
    57001 taacatctat gccatcggtg atatcgttcc aggggcggca ttagcacaca aagccagtta
    57061 tgaagcaaaa atcgctgctg aagcaatctc tggcaaaaaa gtagctgtag attataaagc
    57121 aatgccggca gtagccttca ctgatcctga attggcttct gtaggtatga cgatcaaaga
    57181 agcaaaagat gctggtatcg aagcaaaagc atataaattc ccattttcag ggaacggtcg
    57241 ggcattatcg cttggtaaaa cagaaggatt catccgtcta gttacgacga tcgaagataa
    57301 cgtgcttatt ggcgcgcaaa tcggtggagt cggcgcaagt gatatggtct ctgaattagc
    57361 tttagcaatc gaatcaggaa tgaatgctga agatatcgcc ttgacgattc atcctcatcc
    57421 atctcttggc gaaatcgtca tggatgcttc ggaattagca ttaggtttac caatccatat
    57481 ttgatttgaa taatacaggc gaaacgcaac tgaaaaatca gttgcgtttt gttttttaga
    57541 attatcaata atattattat gtaaacttaa aaatatgaca acttcttggt ttattaccac
    57601 ttcctatgct acactgaaga ggaatatgaa ataggagagt tgaagatgca agaatatcag
    57661 tatccacttg atttagattg gacaacagac gaaatggtca ttgtaatgaa gatgtgggaa
    57721 gatctggaac gtgcgaatga aaaagggata aacaatgaag cttttttgaa gacttatcag
    57781 cagtttaaaa ctgttgtcaa atccattggt gaggaaaaac gattgggacg ggaatttgaa
    57841 aaagcttccg gttattcttt atatcgtaca gtgcagcaag caaaaaaaaa tccaaacaaa
    57901 actttgagaa tgaacgggtg agataaatgg aacagatgat tgatcatatc aagtcctggc
    57961 ttgaagaagc tggtgagaaa atcaaatctt ctcaacaaac attaacaatc tcgcaaaaat
    58021 caaatcgaac ggatctagta acaaatgtcg atcgaaacat ccagaatttt ctaatcgaaa
    58081 aaatccattc ctttgatcca gaggcgaaaa tattggcaga agaagaaggg tgtaatcaat
    58141 tatcggatct cgatggaaga gtctttatca tcgatcctat tgatggcacc ttgaattttg
    58201 tgattgaagg ggaaaatttt tgtattatgc tcgctgttta tgaatccggc gttggaaagc
    58261 ttggtttcat ttatgacgtg atgagaaatg aacttttttg gggtggaaaa ggaataggcg
    58321 tgtataaaaa tgatgagcca ttgcctagac cagcaaataa atccttatcg gaaggcttac
    58381 ttggtgtgaa tagttatctt ttcggtcata ataaatatgg aatccgagaa attgcggaaa
    58441 gcagcatggg gacacgtatg tacggatgcg ctggtcttga actagtggca atcttgaaag
    58501 gaaaccacat tgcttatatt tcaaacctta gcccttggga ttatgcagcg ggaaatgtct
    58561 tattggaaga gtttggtatg gtaacaagcg gtctttttgg tactcctttg acatttgaaa
    58621 aaagggaata ctatttagca gggacttctt gtgcatatgc agaaatcgca gaccttttga
    58681 aaaaagaagg ctgaaaaaaa ggtagaaatc attcacaaaa atgataaaaa cgagcaaaag
    58741 attaattttc tcgaaaaaat gaaaacattt tactatattt catgaaaaaa gtctgctata
    58801 attagcagtc gagtaaaatt tgccctgtca taaagaacca ataaaaaagg agttagttac
    58861 attgaattat agaaacgata tccgtaacgt cgcaattatt gcccacgttg accacggaaa
    58921 aacaacatta gttgatgaac tattaaaaca atcagataca ttagacgcac atacgcaatt
    58981 gcaagaacgt gcgatggact caaatgcgct agaaaaagaa cgtggtatca cgattttagc
    59041 caaaaacaca gctgtagact ataaaggtat tcgcgtaaac atcatggata ctccaggaca
    59101 cgcggacttc ggtggcgaag tagaacggat catgaaaatg gttgacggcg ttgtgttggt
    59161 cgtagatgcg tatgaaggaa caatgcctca aacacgtttt gtattgaaaa aagcactgga
    59221 acaacatatc acaccaatcg ttgtcgtaaa caagattgac aaaccttctg ctcgtcctga
    59281 gcatgtcgta gatgaagttc ttgaactatt catcgaatta ggagcagatg atgatcagtt
    59341 agactttcct gtgatttatg catctgcact aaatggtacg tcaagcttgt cagatgatcc
    59401 agcagatcaa gaaccaacca tggcacctat ttttgataca attattgaaa aaatccctgc
    59461 tcctgtcgat aacagcgacg aaccattaca attccaagtt tcattacttg actacaacga
    59521 ttatgtaggt cgtatcggaa tcggacgtgt atttagagga acaatcaaag taggagacca
    59581 agtagcatta attaaattag acggaacagt taagaaattc cgtgtaacga aattatttgg
    59641 tttctttgga ctaaaacgtc tagagattca agaagcaaaa gctggagact tgattgctgt
    59701 ctcaggtatg gaagatatct ttgtcggtga aacagttact cctgtggatc atcaagatgc
    59761 gttacctatc cttcacattg acgaaccaac attgcaaatg actttcttag ttaataattc
    59821 accatttgcc ggtcgagaag gtaaattcgt aaccgctcgt aagattgaag aacgtttgat
    59881 ggcagaactt caaacagatg tatccttacg agttgaacca acaaactctc cagatgcatg
    59941 gacagtttct ggtcgtggag aattgcattt gtctatcttg attgaaaaca tgcgccgtga
    60001 gggatacgaa ttgcaagtat ctcgtccaga agttattgaa aaagaaatcg acggtgtaaa
    60061 atgcgaaccg tttgaacgcg tgcaaatcga tacaccagaa gaatatatgg gtagtgttat
    60121 cgagtccttg agcttacgta aaggtgaaat gcaagatatg gtccatacag gaaacggaca
    60181 aatccgtttg acattcttaa cacctgcccg cggtttgatt ggttattcaa ctgaattcct
    60241 ttcaatgaca cgtgggtacg gaataatgaa ccatactttt gaccaatatc tgccaatgct
    60301 tcctggtcaa attggcggac gtcaccaagg ggcgcttgtt tcgatcgata caggaaaagc
    60361 aacgacttat tctatcatga gtatcgaaga acgcggtaca gtcttcgtag aaccaggtac
    60421 agaagtatat gaaggaatga ttatcgggga aaacagccgt gataatgatt tgactgtcaa
    60481 catcacgaaa gcaaaacaaa tgacaaacgt acggtctgct actaaagacc aaacatctgt
    60541 catcaaaaaa ccaaaacaat tgacgttgga agaatctttg gaattcttga atgatgatga
    60601 atattgcgaa gtaacaccag aaagcattcg cttgagaaaa caaattttag agaaaaatgc
    60661 tcgtgaaaaa gcatctaaaa agaaaaaata atctgtaaaa ggatgaagag agaaaccagc
    60721 ttgttataaa aaatagctgg tttctttttt tgtccaactc ttttctgtgg agaagtcatc
    60781 tttgtcaatg gacataaatt cagaaaatac gccgaaagac gtttaaaaga cttttaaaaa
    60841 acttatttct agagagtttt tgtttcataa taagataatg tttcacgaaa ggagatcaac
    60901 ttgtccttcg aagaaaatcg aagtaaaatg gcaagagaaa ggagcgggaa gatgaacgac
    60961 ttattaaaac aatactttgg ctatgatgag tttagacctg gtcaaaaaga aattatccag
    61021 aaagtcattg atcaggaaaa tgtattagga atcatgccta ccggaagtgg gaaatcaatc
    61081 tgttaccagc ttccagcttt actattagat gggcttactg tggttgtgtc ccctttaatc
    61141 tctttgatga aggatcaggt ggacgcggcg aatcaattag gtatacccgc cacttttatc
    61201 aatagctcgt tagatggtta cgaaacagct agacgcttcc aagaaatcga tagacagcag
    61261 taccgtttac tttatatcgc tcctgaacgt tttatcatgc cggattttat ccaagcaatg
    61321 aagcgatgga acgtccgtat gatcgctatt gacgaggcac attgtatctc tcagtggggg
    61381 catgatttcc gcccaagtta tttacagatg gcgaaccagc tagatcaact gccaaatcgt
    61441 cctgtaattg ttgctttgac agctacagcg actgtgcaag tagctgctga cataaaaaga
    61501 cttttaaaaa ttccagaaaa caaccatatt cagactggtt ttgaacgaga aaatctacga
    61561 tttcaagtaa ttaaagatca aaaaaaagaa caatatctaa tcgaatattt aaagatcaac
    61621 aaaaatcaat ctggtatcat ttatgcagca acgagaaaag aagtagaccg tctctatcat
    61681 ttgcttaaaa aattcgattt ttccgtgggt agatatcatg gtggtctaaa tgagaatgag
    61741 cgaacagaaa tgcaagaagc ctttttatac gatcgcttgc agctgattgt agcgacaaat
    61801 gcatttggta tgggtagaaa taaaagcaat gtccgttttg ttatccatta tcaaattcct
    61861 ggctctctag aagcatacta tcaggaagct ggtcgggcgg gaagagatgg tctttccagt
    61921 gaagccatcc tgcttttctc tcctcaagat atccaagtcc aaaagttttt tatccagcag
    61981 tcccaaagag aagaagggca aaagcaaaaa gaatatgaaa aattaaaagc gatgacagaa
    62041 tacgtgtata ttgagtcctg tcttcagcaa tacatcctaa actattttgg cgagacaagc
    62101 agtccgtgca accgttgtgg taactgttta gatgacagag aaatagtaga agtaacgaca
    62161 gaagcacaga tggttctttc ttgcttaaaa cgtatgggtg agaactatgg taaacaaatg
    62221 ctgatgaaag tcttagcagg atcgaaagaa caaaagctgc aagctttagg ttttggacat
    62281 ttatctacct atggactgat gaaaaaccaa tcgcaaaaag aaacgatgca gttaattgaa
    62341 tatttgatat cgaatggcta tcttctgacc atcaatggtg agtatcctgt tttgaaagta
    62401 acagaaagag ggatacaagt attgaaagga caagaatctg tttatcgaaa ggaacccaag
    62461 aaagtccagc agctatcgga tgaagaaacc gatacactat ttgaagtgct gcgggaactg
    62521 cgaacggatc tagcatcaga agcaggcgtt cccccgtatg tcgtattttc agattccaca
    62581 ttgaaagaaa tgagccgaat acgtccatca agcagattgg agatgcttca gataaaagga
    62641 gttggccaaa gcaagcttga taaatatggc gaagcctttt tatctcggat aaaaaatgcg
    62701 gactctaacg ttctggataa gtagaaagaa cgaatacgta aaaatgaata aaaacaactg
    62761 gttaaatctg ttttttttgc tccttatgaa aatcaaatat gttataatta aggaattaga
    62821 atgggaggta agcacagatg gattctttgt cgaaaaaact tgcgatccaa gtattaaatg
    62881 atgaagcaga acggatcaaa cgattaatcc gaaatcaaaa caacagtctc tgtatctcac
    62941 aatgcaaagc cttcgaagaa gtggtagata cacagatgta cggcttttcc cggcaagtcg
    63001 gttttgctgt ccgtatagga gtaatcggaa agaacgaggg ccagctgatg ttaagtgagc
    63061 tagaacgaga attgaatcag ttatatagtg aggtttacca agaaatttat gataaaaaag
    63121 aagttggcaa ggaggaatag acttgcctaa gaaagtgaaa aaaaggcatc tattagacta
    63181 tagcatcttg attccctatt taattttatg tgtattggga ttgatcatgg tatatagttc
    63241 tacgtcgtat ctattattag aaaacggaca aaatccgtcc gcatcagtca ttaaccagag
    63301 tattttttgg gtgcttagct tgattgctat cgcactactt tataaaatga aaacagatgt
    63361 tttgaaaaac cagcgtttga tcatggcagc catcgcagtt ttgacgattt tgctgctgat
    63421 tgttgtgttt tttggtaagg agatcaatgg ggcgaaaggt tggctgcaaa ttgcaggatt
    63481 ctcgatccaa cctgccgaat acctaaaaat catttctatc tggtacctgt ctctgacttt
    63541 atctaaaaga caaaacagtg tacaaaaaga ttttcttggg actgtgaaac gtccacttgc
    63601 aatggttatc ggacttactg cattagtcgc tattcttccc gattttggta atgcggcagt
    63661 tatctttttg attattttgg ttctgctttt agccagcgga gtcaattatg tgtatacttt
    63721 gattgtagga gtaggaggct tttgtctaag tacttttacg atctggctga tcaatatcac
    63781 aaacggaaag atcttacccg gacgtttaca gtatatctat aatcgatttg ctatttacca
    63841 aaatcctttc tcagacgaat taaataaagg gcatcaacta gtcaacggct actatgccat
    63901 gttcaacgga ggactatttg gcaggggatt aggtaacagt atccagaaaa aaggattttt
    63961 acaagaagca caaaccgatt ttatttatgc aatcgtagtg gaagaactgg gagtgattat
    64021 ggggattttg atattagcgt tgctattctt tatgattgtg cgcattgtcc ttgtaggtat
    64081 ccgttcaaaa gatccgttca attcgctttt gtgcattggg atcggcgcaa tgtttttgat
    64141 ccaagtattt gtcaatcttg gaggaattac tggcgttatt cctttgacag ggatcacgtt
    64201 cccattttta agtcaaggag gctccagttt gctgatgctt tcgatttgtg tcggctttgt
    64261 cctcaacatc agtgcggatg aaaaacgcaa gagcttaggt ttataataaa aaaagatgta
    64321 ggagtggttc gatgaaaaaa gttttagttg ctaacagggg tgaaatcgct gtacgtgtat
    64381 ttcgtgcttg tacagaatta ggaattaaaa ctgttggaat ctatgcagaa gaagatgaat
    64441 attccgtaca ccgtttcaaa gcggatgaag catatttagt aggacaagga aaaaaaccga
    64501 ttgatgcgta tctagatatt gaagggatca tttctatcgc gaaagaatgc ggagctgacg
    64561 ctattcatcc gggttacggt cttttgtcgg aaaacttgaa ttttgcgcaa cggtgcgaag
    64621 aagaaggcat catttttgtt ggacccaaac tgcatcattt agatattttt ggagataaaa
    64681 tcaaagcaaa agctgcagct atcgaagcgg ggattgcttc gattccaggc acagatggac
    64741 caatcgcttc tatagacgat gccttggagt ttgcgaaaca atacggttat ccgattatga
    64801 tcaaggcagc tctaggcggc ggcggacgcg gcatgcgtgt agctcacgat gaaaagagtg
    64861 caagagaggg ctacgaacgt gcgaaaagcg aagcaaaagc agcctttggt agtgatgaag
    64921 tgtatgttga aaaatacatc gctaatccta agcatatcga agtacagatt ctcggggata
    64981 cgcatggaaa cgtcatccat ctttttgaaa gagattgttc tgttcagcgc cgtcaccaaa
    65041 aagtagtaga agtagcgcct tgtgtctcta tgaatgaaca gcaacgtcaa aaaatctgcc
    65101 aggcagctgt ccaattgatg aaatatgtcg ggtatgtcaa cgcaggtaca gtagaatttc
    65161 ttgttgaagg agatgatttt tactttatcg aagtcaaccc tcgcgtccaa gtggaacata
    65221 cgatcacaga aatgattaca gatattgata tcgtaacaac gcaactgttg attgctcaag
    65281 gtttggatct gcataaagaa atcggattgc ctcagcaaga aggaattaaa ttaaatggtt
    65341 cagccattca atgccgaatc actacagaag acccgttgaa taacttttta ccagacacag
    65401 ggaaaatcga tacgtatcgt tcacctggtg gttttggcgt acgtctggat gtcggaaatg
    65461 cttacgcggg ctatgtagtg acaccgtatt ttgattcatt gctagtaaaa gtatgtacgc
    65521 atggtgctac ctttgaaaca gccattcaga aaatggaacg ttgcttgaaa gaatttagaa
    65581 tccgtggagt gaaaacaaac attccattta tgctcaatgt catcacacat cctgaattcc
    65641 aatcaggaaa tgcaaaaaca accttcattg atagtacagc aacattattt gaatttcctc
    65701 gactacgaga ccgcggaaac aaaacgatga aatatatcgg tgaaattact gtgaatggtt
    65761 ttccaggtat cgaaagtggc gaaaaaccat tttatgaaga accacgtatg cctaaagatc
    65821 taatcacaag aactgattac gtaacggcta agaatgtatt agatgcgaag ggtgccgatg
    65881 ctttggtcga atggatcaaa ggacaggaaa atttgttgtt gacggatacg acatttagag
    65941 acgcccatca aagtctgcta gcaactcgtg ttcggacaaa ggatttcaag cagattgcac
    66001 gtttgactgg agaaggtctt cctgaactct tttcaagtga gatgtggggg ggagcaacat
    66061 ttgatgtggc ttaccgcttt ttgaatgaag atccttggca acggttgaga aaaattcgtt
    66121 ctttaatgcc taatacgttg ctgcaaatgc ttttcagagg ttcaaatgcc gttgggtatt
    66181 ctaattatcc tgacaatgta ttggtggaat ttgtcaaaga agcagcagcg caaggaatcg
    66241 atgtatttcg aatctttgat agtttgaact ggactccaca aatggaaaaa agtatccaag
    66301 ctgtacggga tactggtaaa atcgcagagg cagctatttg ctatactggc gatatcaacg
    66361 atccaagtcg ggcaaaatac aatgttcagt attataaaga catggcaaag gaactagaac
    66421 aactgggtgc gcatatcatt gcaatcaaag atatggctgg gctgcttaaa ccgcaggcag
    66481 cttatcgttt gattagtgaa ttgaaagaaa cgacagatct gccaatccat ctgcatactc
    66541 atgataccag cgggaatgga atcatcactt attctgctgc ttcaaaagca ggagtagaca
    66601 tcgttgacgt ggcaatgagt gcaatgagtg ggaatactag tcagcctagc atgagcagct
    66661 tgtattatgc actggtcaat ggtccacggc tgccagaaat cacgattgaa aatgcacaga
    66721 aattaaacca ttattgggaa gatgtgcgca tgtattacaa accgtttgaa aacggcttga
    66781 atgctcctga aacagaagta tatatgcatg aaatgccagg aggacagtat tcgaatctac
    66841 agcaacaggc aaaagctgtc ggattaggtc atcgctggga tgaaatcaaa caaatgtatc
    66901 atactgtcaa cttgatgttt ggcgatatcg ttaaagtaac tccatcatct aaagtagttg
    66961 gagatatggc actatttatg gtccaaaatg atcttacaga agaagatatt tatgaaaaag
    67021 gcgaaacact aagtttccct gaatctgttg tgactttctt ccaaggagaa ctagggcaac
    67081 ccgttggcgg atttcctaaa aaattgcaaa agattattct taaaggcaga cctgcattga
    67141 atgaacgtcc aggtcttttg gctgaatcag tcgacttcaa cgaagtaaaa aaagaattgg
    67201 cagaaaaaat tggctatgaa ccaaaacaag acgaagtatt aagctatttg atgtatccgc
    67261 aagtcttttt ggactatcaa aaagcatata atcaatttgg cgatgttaca ttactggaca
    67321 caccaacatt tttccaaggt atacgtttgg gtgaaacaat caatgtacaa atcgaacgcg
    67381 gaaaaacgct tatcattcgt ttagatgaaa tcggagaacc cgatatcgaa gggaatcgcg
    67441 tactgttctt caatttgaat ggacaaagac gtgaaatcac tatcaaagat aattcgatca
    67501 tcagtacggt ccaaacccga ttgaaagctg aaccgacaaa ccgagaacaa attggagcaa
    67561 cgatgtctgg ttctgttttg gatgtattag tgaaaaaagg cgataacgtt aaaaaaggtg
    67621 atacgttgat gattactgaa gcgatgaaaa tggaaacggc catcgaagca cgttttgacg
    67681 gagaagtcgc acatgtatat gtgtcttcag gagacactat ttcgtctggt gaccttttga
    67741 ttgaagtgac tgagaaataa taagcgaaag gtggggaaac atgaaaagac tgggtttgtt
    67801 ttggctgatt ctgctattag ttattgtggc attctacatg gaaccagtct tgtttccgcc
    67861 aaaacttgaa gtgaaggaaa actctgatca acaaatatca aaccaaatga caacgtggaa
    67921 ataccaggag cttaaagcaa ctggtttttc tacttatatc ggaaaaccga tcgatcagct
    67981 ggaaaaggat tttggccaag cctatgatcg attaactagc ggatttggtt ttgaaacaag
    68041 atattatgaa aataaagcta gtcatctcac atttgaagcg aacatccaag acagcagagt
    68101 cacaactgtt aaagtactgc aaacagggcc tgctgatatc gcgccgtttt atttagggat
    68161 gacgatgcaa gatcttacga aaatcactac tatctatact aatttcactt ttgagtacca
    68221 tgatacagaa gttggaatcg aactaatgga agaggatatg aattatcgtc cgctaattgc
    68281 ttttgataac gacacttttg ctattttatt ttttgatcaa acaacaaacg gcctattttc
    68341 agttgtgtat ttagataaag atagtctttt gaaactattg ccatatcaag tgtttggtga
    68401 aggccttcca cattatcaag cagataaatc ggctgattgg gaatcaatca atcgcgttaa
    68461 agaacgaaaa agtacgactt tattaaatat gcttagaaga gaagacgaac ttcccatata
    68521 caatcaaaca cttgcctttc aaaaccacag tcagctgcta ctacatgatt ttttgacaag
    68581 gcctgaggaa atattgtcag aggaacgtat ggctgattgg caaaaatcgc taggcagtgc
    68641 tcaaacgaca gtgaaattct cactgacgaa tgatgaattg gagaagttaa tcagtaaaca
    68701 aaaattagaa aatactagtg ggctatttat tcatccggcg attgacgcta ctttttcgtt
    68761 tttatattgg tacagcgatc cttacaacca tgaccgtttc atggacccgg gaacggattc
    68821 tgtaggcatt gctttttcta aagaaaatat gttagtctta ttgcaagaag aaaacggaga
    68881 aagtagtgat agcagtgatc gttaacgaag agctgtttca actggaggat caatgcctcc
    68941 aagtcgctga aatgataaaa aagagtaaaa cgatggcttc ttatcttgaa cataaacagt
    69001 caatggaaga atctgcaaaa gtttgccagt tgaaagaagc gttcttgtct aagaaagaag
    69061 catttgaaaa tgtagcggca tatggtgagt atgcacctga ttatcgtgaa aaaaaacgag
    69121 ctgttcgaaa agcaaaaaga cagcttgata tggatgagca tgttgcagct ttccgatata
    69181 gtgaaacaca gctgcaaagt ctgttggatc aaattgtcca agtacttgcc gaagaagttt
    69241 ctaatgaaat caaagtagat gcaggtagcc cgttttttga aacgaaaaaa cactttggat
    69301 gcggaggtaa ttgtcatgca attagacaat agtgaatttg aaataacaaa acgacgcggg
    69361 ctgatcgtat gggtctacag cttaaaacaa ttaaagaatc tgaaaaagtt cggcttgttg
    69421 cattatgtct caagaagaat gaaatatgtc gtgctttact taaatgaaga gacattggaa
    69481 gaaacagaag aacgaatccg taaattacat tttgttcgaa acgtagaacg ttcttaccga
    69541 ccggatatcg aaatgaattt tgccgaaaaa ataggaaaca aaacagtatt aaaagacgaa
    69601 ggtttcgaaa ttgaagagct aaatacagaa atccgattag ctgaacatct ttaaaaatct
    69661 cttatgagca gtttttaaat aaaaaataac ttggataacg atcgattttt gatcattgtc
    69721 caagtatttt tttggtatac tagtaccagt accatttcta aggagtgagt agatgcggat
    69781 aatatcagga aattatggcg ggcgccgttt aaaaagttta gcaggggcga acaccagacc
    69841 aactacagat aaagtaaaag aatccatatt caatatgatt ggaccatatt ttgatggaga
    69901 gacagtattg gatctgtttg caggaagcgg tggtttagct atcgaagcag tatctagagg
    69961 ctgcagtcat gcggtatgcg tagacaaaaa ttaccaagcg ctaaaaatca tcaaagaaaa
    70021 catcgaaatt acgaaagaac cagagaaatt taccacaata aaacttgatg cggacaaagc
    70081 aatcgaacgg ctagcagcgg agaaacaaca attcgactac ttgtttcttg atccgccata
    70141 tgcaaaacaa aaaataatcg atcaaatcca taaaatggaa gaactgggac ttttttctaa
    70201 aaccgcagtt atcgtatgcg aaacggataa aacagtcgaa ttgccagaaa ctgtggctgg
    70261 attccatcaa ataagaaaac agatttatgg cataacggcc gtaactatct atagaaaaga
    70321 gggaaatcaa tgaaacgtgc attattccca ggaagttttg atccttttac aaaaggtcac
    70381 ttagatacgg tggaacgtgc ggctaaatta ttcgatgagg tagtaattgg tgtttttatc
    70441 aatacttcaa agaaaagttt gtttccccca gaagaaagaa tgacattgat cacaaaagct
    70501 gtttctcatc ttcctaatgt aaaagtcatg catcaagaaa atcaattgac ggtagaaaca
    70561 gcaaaagaga ttggtgcaga tgcgttgatc agaggcatac gaagtatcaa agactttgaa
    70621 tatgaacgag agattgctca gatgaatcat catctatatg atgaattgga aactgtcttc
    70681 ttattagcaa aaccagaata tagtcacgtg agttccagta ttttaaaaga agtactgcac
    70741 tttggcggag atgtgagcag ctacttaccg ccagtgatca acgaagcttt agctggaaag
    70801 cgtgaatcaa atgaaagcta aacaatggtt gaaaacagta ctgattatca tatttggaat
    70861 gttgatcatt ggatttgtag tagttccctt gccgtattat gtagaatcac cgggagccac
    70921 gatcgatctg aaagaactaa ttacggtcaa tgataaggaa gataaaggtt ctgggtcttt
    70981 ctctcttacc tctgttggta tcaggcaagc tacaggtttc ttagctttaa aagctaaaat
    71041 gacccctttt gaagaattga tcagtgaaga agaattgact ggtggggcga caaatgaaga
    71101 atataatcaa atgcaacagt attatatgga ttcttcccaa aatgcagcaa tcgaacaagc
    71161 gttaaaactt gcagacaagc cttataaaat ggaattcaaa ggcgtatatg tcatgagtgt
    71221 agagaaaaca tcgaatttct ttggcaagct ttcagttgga gatacagtaa caaaagtaga
    71281 cgggaaaagc tttcaaagta cagaagcatt tatggattat gtaaaaagcc aaaaagttgg
    71341 acaaacaatc gaaatcagtt atttgcataa tggtgaagaa aaaacagctt ctggtgatct
    71401 gatcgagtta ccaacagata aaaaggcagg aataggtatc acgcttactg accataccga
    71461 gatcgaatca gatacagatg ttcgtattaa ttctggctct atcggtgggc catcagcggg
    71521 attgatgttc actttagaaa tctatgaaca agtcactggt aaaaacttgc gacatggtaa
    71581 gcaaattgca ggaactggaa cgatcaacag tgaaggagaa gttggccgaa tcggaggaat
    71641 cgataaaaaa gtggcaagtg cggataaagc tggcgtagag attttctttg caccagatga
    71701 tacgatttca gacgatgtta agaaagaata tcctgaaata aaaaccaact acgaagaagc
    71761 aaaagctgcc gctaaaaaat tgaattcctc aatgaaaatc gtaccagtaa aaacagtaca
    71821 agaagcgctt gactatctag agaaaatgaa atgaaactaa ataattaaag aggggttgtg
    71881 acacgagttc tgtcacaacc cctctttttc gtcaaaaatc ttcacgataa aaataaaaac
    71941 aaaagaaaaa attgacgtaa ttagatgttg aagggacgat tttgccagag ctcactgttt
    72001 cttcaatttt aaatgaaagg agtaatgaat gatttttact ggtcattctt tgaaaaaaga
    72061 acaatgatag aaaaaatcag caagaaaata ctagcttcac ccaaattgat catttggatg
    72121 tctatgatag ttcttatctt ttgtatcgca agtggttttt tattatcaaa tttgctattt
    72181 tatagagaaa cagaagagac tgctgcaaaa gaaatacttt cttcgtttag ttccagtgga
    72241 gaagatccat cagctgaagg aaacgatgta gaagaggatg ctcgtccaaa ggtcatgtac
    72301 accgatatca aaggaagtgt gaaggagcct ggtatctatt ccttttcttc agaagaacgg
    72361 gtctatgatg tactaaagcg tgcaggtgga ttattagaag aagcggatag cgatcgaatc
    72421 aacttttctg cgaagataga agatcagcaa gtcctatata tccctgctgt aggtgaagag
    72481 ctgccagaac atcttgatca gttggcatcc tcggaaggaa aacagcctac agcagattcc
    72541 gagcctccca aaataaatat caatacagcc actccatcag aacttcagca gattcctggg
    72601 atcggatcag tcaaagcgca agaaatcatt cgatttagag aagaaaacgg atccttccag
    72661 aaagtggaag acctgcagga gatttctggt atcggtgaaa agacagttga aaaactaaaa
    72721 aacttcgtta caattaaata gaatgattca aaatcgactg gcacgagcaa taaatggacg
    72781 ctaatggata ctaagaataa tccaattcta agagcttggc aggacgagga ggtagtattt
    72841 ttggatagga aatagcttga ttgttcgcaa agaaacatta aaaaaaccaa tgctgaatgt
    72901 ctatctccaa aataaaatat ctgggattca tattatgaat acggctgtca gcggcaataa
    72961 cagtcaagct ctacgagaac gctttgccaa agatgtactt agctatacag cagataaagt
    73021 atttattctc attgggacga atgatctagc agagcataaa caactttcta aagaaacgta
    73081 ccaaaaaatc tgcagtggat gatagttcag ctgaaaaaag actatagttc tgatcatgct
    73141 ttctttatca cgccaccagc agtcgatgag acaaaacaaa aatatcggaa taacaagttg
    73201 atcaaagaat atatctctgt tctcacagaa gtagcaaaac gccatgattg tgaagtatcg
    73261 atttttatac ggaatttctt gaacaaatgg attcgaagaa tttttataat gggctaatgg
    73321 atgacggact tcatttcggc agtgaagggt aggatctttt gtcagacagg atgattcgtt
    73381 atatttaaag aatattttgt ttaagcaatg agtacttttt aatcaacttg aaaaaacgga
    73441 ggaatataaa acatgttaga aaaatcttca aaagcatgcg atacgaataa agaaaaagtt
    73501 actgataagt cacataatga acgcattcct tgggaccagt actttatggc tcaggcagta
    73561 ctgttatctt tacgtagtac gtgtacacgt ttagaagtag gagcgacact cgttcgagaa
    73621 aaaaggatca ttgctggcgg ctataatgga gcagtcagtg gagatgtcca ctgcatagat
    73681 gaagggtgtt acgtcgtgga tggacactgc ttgcgaacga tccatgcaga gatgaatgca
    73741 ctcctacagt gtgcaaaact tggtatcccg acggaaggtt cagaaatcta tgtcacacat
    73801 tttccatgtt tggcctgtac aaaggctttg ttgcaagctg gtgtgaaagg gatcaattat
    73861 ctccatgact atcgaaatga tccttatgcc caagcgttga tcgaacaatt aggtgtatct
    73921 gtacaccaag ttgctttaga ctcacagcat ttttcaaaac ttcaaaatga attaacagga
    73981 aaacatgtct agcgttttag aaaggcatgt tcgaaatcgg ttgatttttc cggcaattac
    74041 gtcgatgatt atctgtttgt tgtattacac tgacaattgg ggttatcgtt tgcttcttgc
    74101 cggaattttt ttatggtttt cgctaaaaga aggacgtttt atcgcgtact tgtgtatttt
    74161 gtgtagcata acggtatcca tttcttatag gctacaagag tattcatttt tagaggaaaa
    74221 aacaacatct gcgcaaatta ctgtatttac agatacgatt cgtgcaaatg gtaatttttt
    74281 gacaatggaa ggaaggttat cagagaataa acaaaagctc cagctttctt atcaagtaaa
    74341 cacagaagca gaattgaaaa catggcttaa cttccgagga aagggaatag aattgactgc
    74401 tgaaggcgag ttcatctctc cagcaaaaaa gcggaatctt tataattttg accaagaagc
    74461 ttacttcagg aaccatagaa tttctggacg gttccaaatt caaaagattg aacagatcac
    74521 catgcaaaat cactggcgaa actggcttca gagaaaaaga ggatctttta tctcctttgt
    74581 ccaatctgaa tttccgcaaa aaacaagtgt atatattaat tctttattat ggggctataa
    74641 agatgcagga ttcagagaac cagaagaaat ttttagggag agtggtttgc tgcatctgtt
    74701 cagtctatcg ggtctacaca tccaatttta tttagggtgg ctgtattatt tatttcgacg
    74761 tatcggatgg ccactacacg tcagtattat tccgttgagt ctactaacta tctgttatgt
    74821 ttctattgca ggaagttcta tttctgtttt gcgtgctagt ttgctgtttt tattgcgatt
    74881 gctagtcaaa ttgctgaata agcattattc caccatggac ttatttgcag ttgtcttttg
    74941 gcttctttta ctatttgatc ctcgatttct ttttcatgcg ggtggacagc ttagtttttt
    75001 catgagtttt ttgtttatcc tgatttcttt tgatggagat tggttgaaaa aaacggcctc
    75061 tcacgtcctg tttactatga tcacgatgcc gttgattgta tggcattttt atgagtggcc
    75121 tattttaggt agtcttttta cattactgat tgcaccggta ttcaagtttc tttttcttcc
    75181 tggtgtgtta tttctcacac tcttcaatcg ctggctgccg gaaactttac ttttgttgat
    75241 agaagaggga ttaatcttat ttgagcgaat aatcgatttt tcttcagggt cgtctctcat
    75301 tataggacgt ttgccccttg tgctatctgg gatgtatatt ttcggattac tgatttgtat
    75361 ggataggttg aaagaacaac ctgtgaaaca cttgttttat gttggtcttt tttcttttat
    75421 ttttttgact ttgccatttt tacgcttttc ttcaacgatc gcttttatcg atgtcggtca
    75481 aggagacagt atctttttgc aaagtccttt tcgaaaagaa acgattttga tcgatactgg
    75541 aggtcagtta cactttgaaa gagaaaagtg ggcgcaaggt atgatacgtc ctcctgctga
    75601 aagaaatatc gttccatatc taaaaggtca ggggataagt gtaatcgata aactcatctt
    75661 gacacacgac gatacggatc atgtgggaga attacccacg ttatctcagc attttactat
    75721 caaaaaaatt tatatcggtt ggggcgctgg acgaaatgag ccattacaaa ggcatttatc
    75781 tgaagctcaa aaaaatggta ctgagatcat tgaaatcaaa catggggaca ggatcagcgg
    75841 ttattatgat ctttatgtat tgactccttt tgaaaaggga gagggaagaa atgaagattc
    75901 gattggtcta tggatggaat ataacaatag gcgcttttta tttttaggag atttgaatca
    75961 agcaatggaa aaacaattgc ttttgattta tcctaatctg aaagccgatg tagtcaaatt
    76021 aggtcatcac ggtagccgta cgtcaagtaa cacagatttt ctttcccata ttgaagcaaa
    76081 acatgggatt atatcctgcg gcgtaaataa tcgttatggt cacccgcaca gcgaagtatt
    76141 ggagacacta gaagaaaatc agataaaaac atggcgaacg gatcaacaag gaatgatcac
    76201 ctatcgctgg catccagttt ttcatcctca tgggctagtg gaaacaatga tagactagta
    76261 attctcatct gctcatggta ggataatttt tgaaagtggt gagtaatttg agtatacaag
    76321 cagagttaca aaaaatacgt aaagaaaaac ttgcatcttg ttacttgatt ttaggaacag
    76381 aaaagtttct ccaagatcaa gttcggacag aaattgtcaa aaaaatccaa ttagagggcg
    76441 aagatgactt aaatttttta agttttgaca tggaaaatgc aagtttagat gaggtagtag
    76501 ctgaagcaga gacgttgccg tttttcggag atcaacggtt agtattcgta gagaatcctt
    76561 attttttaac aggtgaaaaa gtaaacaatg gaatcgaaca aaatactgat ttattgacgg
    76621 cttatttgaa agaaccatta gaatcgactg tattagtatt ctttgcgcca tatgaaaagt
    76681 tggatgaacg gaaaaaagta acgaaacaat tgaaaaaaac agcaattatc atcaatgtcc
    76741 aacagttgaa tgaaaaagaa gtacgtcaat atctgatgaa taccttagag aattcctcaa
    76801 tcaaaatgga acgaagtgca attgatttat tcttgaggtt gaccgactta gatttatcca
    76861 aaatgatgag agagttacag aaattggtcc tttatggaca aaatcaacag caaatcacgg
    76921 taagagaagt agaagaatta gttcctaaaa cgttagaaca taatattttt gacatgaccc
    76981 aatatatttt aaaagggaag acggaacaag ctttgcgttt atacgaagat ttagttatgc
    77041 aaggggaaga aacaatcaaa attaatgcga ttttgctttc tcaattacgt ttatttttac
    77101 agacaaaatt tcttgtaaag attggttatc agcaggcaaa tattgctgaa acattgaaaa
    77161 tccatccata tcgtgtaaaa cttgccatgc aggaagtaaa aaaattcgat gaacatttgc
    77221 tggtacagtt gtttgatcaa ttagttgaga tggattatca aatcaaaacg ggacaaatcg
    77281 aaaaagaatt aagttttcaa ctattcgttt tgcgcacagg gcagttgtta agaaatcgat
    77341 aagaagaaag acgagggcaa agcatgcggg aaggtcgttt gtttttgtcc tttttttgac
    77401 aaataaaaaa atcggccgaa gccgattctt ttatttagcg atttttttgc ttaaacgaga
    77461 tttgtcgcgg ttagctttgt ttttgtggat tagacctttt gattcagcca tatcaatagc
    77521 tttaacagct tctttatata acgcatctac gttgtcagca cctgaagcta cagcatcttc
    77581 aaattttttg attgcagtac gcatagcgct tgtttgagat gaatttttca cattagcgtt
    77641 ttcgcttgta cgaacacgtt tgattgcaga ttcaatgttt ggcattagtt tcacctccga
    77701 taacttaagt tcttacgcgt gttaccgcat aattcaacat tcattattat acctaaaggc
    77761 agcgtgcttt gcaatatgaa catgacaagt ttttttcctt aacagtcttt tattaggatt
    77821 ttttttcagt aaaaacggat agtacaagct gaaaaaaatc aaaaagacgc tattgtggga
    77881 ggcaatagcg tcaaaccaaa ctagattttt atttatctat ttaaacaaag tttgaatggg
    77941 aatgtttggt actaagttat tatataacaa agagaaccgt ttgcaaagtt ttttttgaaa
    78001 agggatacga ttccctgttg ttctttgttt ttctattaag aaactgcagt tattttataa
    78061 ccagtatcct ttgatcagta aaggctattc tggtgtaccg attattttaa tgtattcatc
    78121 gatatttttt atcaacattt tttttatgac caactggttc cgacggttcc atttgccact
    78181 tacttccagc acatatttat ttaggggcaa acgtaagata tattttgcca aatagcgatc
    78241 tttaagcagg ccattgatca cacggtcctc aagctgcaag ttgatcccag tcagcatcat
    78301 tggctgttct tgtaaaacgt acgtatcaat taaaagacct tcaaaagttt ccacaagcgt
    78361 cttcctttct tttcaaagta acctgaaaac aggcactaat tcttccattt tgatattcgt
    78421 tgaagtggat gcgatcattc tttcttttgt ccactgtaat ctagtataac aaaaaagagc
    78481 agaagagcca aaaagaaaaa agagcatcga attctatagg aagtctcatt ggcacggcct
    78541 aaattattac aaaacattga ttaaaaaaag cccctgcatc gcaggagcat cccctatatc
    78601 gttttaatag gtcaatcaaa aagcagtatc aaacacattt tgtatcaaat caggaaataa
    78661 tagataagct aagcccagaa tcaaaagtac cgctagaaga aaccagccga ttgttcctat
    78721 gaaatacttt aatttttcga acattgtatc acctcgttgt cagtatatca cggatcagta
    78781 aattgggggt gttaagaatc tcctaaaata gacaaaattt gttctatttt cctaaagcaa
    78841 atacttgtaa gatacagtaa gtgataccag aagcaatgac cggtccggcg gcgattcctc
    78901 ttaagaagac aacacctaaa atcgtgccga aaacaagtgc aacagtgatt tgtggatcag
    78961 aagcaatcaa tcctacaccc ttggaagata agacagccac tagcccaccg caaaaaacag
    79021 ctacccagcc aataggggat ttaaaggctt ctaatagatc acgtagaccg atttctcctg
    79081 ttgcgatagg gattagaata gccgctgtga tgatcgtcac cccaatattg attcctttgc
    79141 cttgaagcca agggaaaaag gaacgggagg ctggtatgag cttcataatc aaaacaaaag
    79201 ctgccgctat catcagactt tgatttttag ctaaaattgc tacaagtaaa ataattccta
    79261 aaaaaagcca actttccatg aaatatattc ctcactttct tcgaaacaat cataacatgt
    79321 ttttagaaag ttacaaaagt aggaattcat ccttcaagac ctattcataa gctgtttttt
    79381 tcataaaata aacaaaatca taaaaaaaca ctttgcttat ttgacagaag acagccgcgc
    79441 tttgtatagt ggacaagact tacatttttt tgaagaatca gaaagatcag gtaaaggtct
    79501 tagtaaacgc aagccattca gaataaccaa tattgtgctt ccttcgtgtc ctacaactcc
    79561 aagaggtaga tttaaaaatt gcaggaagtt agaagcaatc aacaagagaa taacaagaat
    79621 cgaaaaaata atattttgtt tgatgatccg ccgcattttt aaagatagcc gatgactgta
    79681 gacaaattta tttaagtcgc ttttcattaa gacgatgtct gcgatatcca tagcggcatc
    79741 tgtcccttgc cccatagcga cacctaaaga agcggctgct aaagcaggcg catcattgac
    79801 tccatcacca accatcgcat ttacttggta aagttcattc tcttttttga ctagttgtgt
    79861 tttttcttcc ggagtacagc ttgcatagta atgttcaatc cctacttgtt cagcaatggc
    79921 ctttgctgtg ccagaatggt cgccggttat catacttgta tggatgtttt gggatttaaa
    79981 gtaggaaatt acttgttggg tatttgcttt tggaatatct agcagaccta aaacagcaat
    80041 taactgctga tctttagaaa gataaatcac ggttttgcct tgattttcca aacgttcgat
    80101 catttccgca atctctttgc tgattatcat cgtctcagga tcatatgcgt gcttgccaac
    80161 tttccattgc gcacctaaat aggtagtttg taatccaaaa ccagtaattt cttctattgg
    80221 taagtattgg atttcttcag gtattgtgca atcgaaatat tgcaaaatcg catgagcaag
    80281 tggatgcgtc gttttttgtt ccatagcaac aagaagttgt tgtgccaaat ccttttcatc
    80341 aaagaaaaag ctgtcagtta caactggttt tcctttagtg agcgttcctg ttttatcaaa
    80401 ggcaatcgct tttaattcag aaagcttttc taaatggata ccgcctttga ttaaaatccc
    80461 attttttgca gaatttgaaa gagcagctag agaagctggt gtagcagatg cgacaagcgc
    80521 acaaggagaa gccacaacta ataataccat tcctcgataa aagctttcat cccaactcca
    80581 acctaggaaa aagtggggga gaaggatcat tagaggaaca gcaagcaaaa tcaattttac
    80641 ataattattt tcgattcgtt cgataaatga agctgtttga gttggcgtat tctgcgcttc
    80701 ttctactaat tggataatct tagcaaagac agtttcggaa ctcgtttttg ttactcgaat
    80761 cgtgatggga tttccttgat tcagcgttcc tgcatacatc tcatcgccta aatatttttc
    80821 tacaggcaca gattcaccgc ttaatgcaga ctcatcgatc gttgcctgtg tgctttctaa
    80881 aaagccatct atcggaacag ctgctccttt agcgacaaat accaagttat ccacctttag
    80941 ttgagaaaca tctacttctt gcatttgtcc attttctttt aataattggg ctttttgtgg
    81001 ttgaagattc atcaaagcag taatttcttt ttgactttta ttagttgtgt attcctctaa
    81061 tgcaccgctt aaacaaaaga tgaatgtcaa cattgctcct tcaaagtaat taccgatcaa
    81121 acaggcacca atagcagcta aagccatcaa taaatccaca ttcagtgtcc gatcattcca
    81181 caattctttc aagccttccg atgtttgttt atatccaccg atgataatgg cactgatata
    81241 aaaaagtggg gtgatggtaa gagagaatcg gtcgaagata aaaccgaaga tcataaataa
    81301 aaggcagccg attgttgctg caaaagcttt tttctgatta gtcatcgtta ttagacctcc
    81361 ttgtcaaaac aaggatagca taataaaaat gtaattgata ataataacag ctaaatgaga
    81421 acgataatgg ttatcatttg gtgattaagc ttgatgttgt ttttattatt tataatgatt
    81481 attattaaag aaaataaaaa accagaacat ttctcaaata agagaagtgt tctggttttt
    81541 tctacattgc aataaaccaa taaccaatca aaatgatacc aaggataata cgataccagc
    81601 caaaagcggt aaagtcgttt ttcttcaaat agcttagtaa gaatttgata gctaagacgg
    81661 aaaccacaaa agatacgaat gttcctacaa gaagaacaac agtttcttcc attttgaatg
    81721 aattcccttc agctaaatat ttgacgatct tcaagccgct tgcgccaaac atgacaggaa
    81781 tccctaagaa aaatgaaaac tctgtagcga caaaacgcga agcaccaatc aagatagatc
    81841 ctaggatcgt tgcgccagaa cgggatgttc cgggaacaag tgccaagact tggaataacc
    81901 caacaagaag agctgcttgg tacgtaaagt cattcagaga agtccaacga ggtgttttgt
    81961 ttttgttgcg tttttcgaca ataataaagg caataccgta aacgatcaaa acaatggcaa
    82021 ctggtaagaa cttgtggaaa tttgcttcta accaatcatc caaaggcaaa ccaatgatga
    82081 tggctggtat gcaagcaacg atcactttaa accaaagtgt ccacgtatct tttttttcta
    82141 ccgttgattt acttggagaa aatgggttta acttgtgaaa ataaagaacg acgacagcca
    82201 agatcgcccc taattggata acgacattga acatcgacat aaattgtgaa ctggcatcca
    82261 gtttgatgaa ttcatctgct aggatcaaat gaccagtact actgatgggc agccattccg
    82321 ttattccttc aataataccg agaatcactg ctttgataat atttgcaaaa aacataaatt
    82381 ccttccttcc caattaagat acatcttata gtataccgtt attttttgag aaacccaatc
    82441 tgttttttaa tattaagaaa aacttgagaa ataaagcaga taagtacacg aagagaaaaa
    82501 agaagacaaa gccctcgttc agactttgcc ttttatgatt ctctggtaaa aattaaaata
    82561 tccccattat agaaacgagt cgcgactatg tgttttcccg ttatcgatat aagacgtatc
    82621 attgatgccg tggatagaaa atcgaccgtt tgcataagtg acctttgtta cgctgccatt
    82681 taaaagccca gcacgaacag gctgtttagg atcgatcaga ttaagcaaaa aggcgatcgt
    82741 caaaccatga gatacgacta aaacatttcc accaccattt ttttcgcagt gatgggcgat
    82801 atcttcaaat cctgtccata cacggtctcg caatgtttca taagtttccg cccacccagc
    82861 ggtatctaag ttgtatacag cattagcaat ttgttcaaaa gaaacttctg tggtaaacat
    82921 ttcatcatat gttttaaaat tcaatacacg agggatcaca ccccacattt ccatgtcata
    82981 tccaccttca agagacccga aacaccattc tctaatcctt ttttcaataa aataaggaat
    83041 ttcttttccc ttagaatgtt ctcctagaat aatacgggca gtttcgattg cacgaccact
    83101 gtcactagaa taagcaaatg aaaagtcgac attttttaac ccgcgaccta aataatgaat
    83161 gccttcttgt ccttgctttg tgaggggtgt atcacaccag ccttgtactc gttcaattgt
    83221 attgaacatc gtttttccgt gtcgtacgat ataaagtgta gtttctgtca ttttattctc
    83281 ctcctaagtc gttttaacga ttgaaaaaag gatttgtcct tttttcctgt tcaatcgtcg
    83341 ttgcatcgcc atgtcctgga tagactgcaa attcatcagg taatacaaac agctgggtcc
    83401 gaatactatg aagtaattgt tctaaattcc ctgtatacag atcggttcta ccgatacttc
    83461 ctctaaacag ggcgtcgcca gaaacgacaa aatcatcaaa aataaagctg acgcttccta
    83521 tagaatgccc tggggtaggg acgacgcgaa aagacatgtt tcctaaagta taagttttca
    83581 tttcaaattc atattctgca ggcgagacaa taacatcagc aatatcatca tgtctaccga
    83641 gtccagaaag attcaaaatc ggatcaccta gccatttttg ctctagtggg ctgacataaa
    83701 ctgggatttg ataatacgcg cgtaaaggtt ccactgcacc gatatgatcg tagtgagtat
    83761 gggtaagcaa aatcgctacc ggctgttggt ttgttttttt gatttcttgt ttgattcgtt
    83821 ccgcatcttc tccagggtca atgatcaaaa gtgcttcttc gttgtagacc aaataacagt
    83881 tttcttcaat cattcctgtt tttaatcttt cgatatgcat gtgcattcct ccttgatagc
    83941 caaaacttct ttcatccatt agtataacgc attcattgct aggaaacaaa aacaggtact
    84001 tatttctctt tacttatctg aattatcaga ctatatgaaa agtatttgga tattctaaag
    84061 agaaggaaag taagttttca tagcatttta atatgtcctt gttacattag attcatccaa
    84121 aaatccaaat tctatatcct atatccctgc ctaatcagca gggtgttttt ttatgtttgg
    84181 aaagagagct ctttttgcta aactaggttt tttcaggtaa tcttagagag aaagaggtgg
    84241 tggaaatgat caaacagtca aaaatatctg tgcggcactt agtagaattt attttgcgac
    84301 gtggaagtat cgacaatcgt aaaaaaagta accatactgc attagaagga gcgagaatcc
    84361 accgcaagct ccaaaaagat gcgggagaaa actatgaaaa agaagtcttt ttaaaaacaa
    84421 cagttcaatt agatgaatat tacctgatcg ttgaaggccg tgcagacggt attttcaaaa
    84481 gagacggtat ttattatata gatgaaatca aaacctccga accacgattt gaagatttag
    84541 aaccagaaca agtggaactt ttctttcatc aagcaagggt gtatgcctat atctatagtc
    84601 aagaacatga tttacaagaa ataaatctgc aattgactta cttccagacg gcagaagaag
    84661 tgatcacgag aaaggttgaa catcagacaa gagagcagtt agaaactttt tttaaaaagc
    84721 tgactgaaga ttataaagaa tggcttgttt ttcaagaaaa ctggcgcact gtacgcaatg
    84781 cctctttgat ggctttgaaa ttcccccatg atgagtatag gaaaggtcag cgtgaactag
    84841 cggtagctgc ttataaaacg atccgtacga aacagaaatt gtttgtagaa gcacctaccg
    84901 gaacaggaaa aacaatctct acgttattcc ccgctttgaa agctgtaggg gaagaagagg
    84961 gagaaaagat cttttatcta acggctaaaa caataactag acaagtagct gaagatgcta
    85021 tgacagcatt aaaagataca ggagctgaag taaaaagtgt cactttgacg gcgaaagaca
    85081 agatctgctt tttagatgag acgacctgta atccagatca gtgcccatat gccaatggtt
    85141 attacaatcg gattaatgaa ggtttatggg atcttttgaa tcatgagaat cagatcactc
    85201 gtgaagtcat cgaaacttat gcaagaaagc atacactttg tcctttcgaa ctatcattag
    85261 atgtcagtat ctggtgtgac gtaatcattg gggattacaa ttatttattt gatccaactg
    85321 tttatttaag acgttttttt gaagatgaaa aaaacgagga ctatctgttt ttgattgacg
    85381 aagcacataa tttggtgaat cgttcccgag agatgtattc ggcagaacta tcttatgaaa
    85441 aaacgaaacg aagtaaggaa gctataccaa aggaattcaa aaaacttcat cgccgtttca
    85501 acaaactatt aaaagaattt gattcgatcc gagaaatagc aaaagaagat cattgggatt
    85561 atcatcatca aaaagcaccg gctgaatctt tagtaaaggc aggttatcaa ttaagcgaaa
    85621 aaattaaaga atggctggca gaatttcctg agcacccatc acaagaacaa ttgcttcctt
    85681 attattttga tttgcttcat tttttgaagg tcagtgaatt ttatgatgat cactacgaaa
    85741 caacagtcga aaaaacgtat cgcgatctga tagtaaaaga gttttgtatt gatccaagct
    85801 tgtttcttga gcagtcgttg gataaaggaa aaagcagtat tcttttttct gctagttttt
    85861 caccactctc ttattatcag gaaacactgg ggggacaaaa aagtctggct tacaaactgc
    85921 cgagtccttt cccagaagga aaccagcaag ttttcatcgc aaattaccta gagacgactt
    85981 atcgaaaaag ggaacacagt ctggcaaaat tagtagagac gattcatgct tttgctgatg
    86041 gaaaggtcgg gaattatttc gttttctttc cttcttatca atatttagat cttgcggtgg
    86101 aagcattcag acagcaatat cccgacagca atgtgctaat ccaagaaacg gacatgaatg
    86161 aggaagaacg cgaacgattt ttaacaaaat ttcaaacaaa tcccgctgaa acattgattg
    86221 gattttgcgt acttggcggg attttttcag aaggaatcga tttgagaggg gaccgattga
    86281 tcggcagtat gatcgtaggt gtaggtttgc cgcagatgaa tcatgagcag gaactgatca
    86341 aatcatatta tgatgagaag gaacaccttg gatttgctta cgcttatcag cttcctggaa
    86401 tgaacaaagt cttgcaagct ggtggtcgag tgattcgtgg catggcggat caaggaatcg
    86461 ttgtattggc agatcaacga ttttctagtt tttcttatcg acgtttattc ccacaacatt
    86521 ggcaaacagc aagagaagta cgaagtgttg gggaattgga agaaggaata cagcgttttt
    86581 ggttatcaaa agaagcagta aatcaaaaaa acgaggaatg acagacgtca gcctcgtttt
    86641 ttgattaacg atagttagtg aattgcaact cgattggtaa gtcaagttta cgtaataaag
    86701 caatcacagc ttgtagatca tcacggttct tacctgtcac tctaatctga tcttcttgga
    86761 tttgtgcttt tactttcagt ttttcatttt tgatagctgt agtgattttc ttcgcgtttt
    86821 cacgatcgat tccgttgacc aaatcggcag tttgtcgagc tttgccacct agagcgtgtt
    86881 ctgattcgga aaaatggata tttttgattg gcacatttct tttgatcagc ttaccaaata
    86941 atacatcttt gatctgttcg attttgaaat catcatcgct caatacaact agattgctgt
    87001 tctctaattt gatttctact gtagaatcct tgaagtcaaa gcgattggac aattcttttg
    87061 ttgtttgctg aatcgcattt tttacttctt ctgtattgac ttctgataca atgtcgaagc
    87121 tagcatcttt tgccatagga accctcctga tatacatata aatatttacc atacatctat
    87181 cttatcatag gattagggca gattcttacc tgtttgctaa aattcttctc atttgagttc
    87241 gaagtatttt attttaatag ataaactgtt attcttacat ttggaatacc aaagtagggg
    87301 agaggtgctt gtgagtaaaa ttatgactgc gtatcataaa aatgaaagat taaagaaaat
    87361 agtggttatt ttgataaccg gattgaccgc tgcggtcgct ttaaattatt ttttgattcc
    87421 agccaatgtc ttttctgcag ggatgaatgg gatcgctcaa atcatttcct cgcttttata
    87481 tgaatggttt catatcaaga tagacacagg aacatttatt tttcttttga atatccctgt
    87541 gtttgtatta gggtttctca aagtaggaaa acgagcaacg atccttagtt ttgtgaatgt
    87601 tgtatgtgta tcggtgatga cgatgctgct tccagtcgga cagatcactg ataatatttt
    87661 gatgaatgcc ctagtaggcg gtgttttatt aggtcttggc gtaggattat ctttaaaaat
    87721 gggctttaca actggtggga tggatatcat ctctcttgta ctttcacaaa caactggaaa
    87781 aacagtcgga aactacatgc tgattctaaa tggtatcatt gtagtcatcg caggcttctt
    87841 ctttaactgg gaaagtgcct tgtatacgat tatttccatt tatgcaatga ctcaagtaat
    87901 tgatgccatc cacacgagtc atcaaaaagt aacagcaatg atcgttaccg tcaagccaga
    87961 agaggtaaca gaagaactag caaaacggat ggtacgtgga atgacattac tgccgtctgt
    88021 cggtggctat tcaaaaaaac aagggaacat gatcatgatg gtcatcaccc gctacgaaat
    88081 gtatgatctt gatcagatcg ttcatgaaat cgacgacgat gcatttatca atattttacc
    88141 aactcattca gtatttggcc ggtttgcaaa tgaaaacgaa caaaaaatgt atcgaacaac
    88201 tggcgtattg ccagaaataa aaaatcgttc acaaaaaaaa tgaggaatca ggtttatttt
    88261 agaataaatt taatctatta catctaataa gaacattttt ataaatttaa acgagaatct
    88321 tacttctaaa ttctcattta caagcagcta aaaaaagagt atgataaata aaaatcgtgt
    88381 taaggagtgt cgtacgatga gcgaagcaaa ccaagaacgg tctggacaag aaatagaact
    88441 aatcaaagaa cgtattcttg ctgccttgga aatggtgatt gatcctgaat taggaatcga
    88501 catcgtcaat ttaggcttga tttatgatat agaattcaat cctgaaaatg gagaaacagt
    88561 cattaagatg actctaacaa ctatgggctg tccattagca gatattttaa cagaatctat
    88621 ccatgacgca ttaaaagaag tgccagaagt aacgaaagca gaagtcaaac tagtctggta
    88681 tccagcatgg acgacagata agatgagccg ttatgcacgg attgcgttgg ggatacgata
    88741 gaaatcttgg ctgactagct atgagaagca aataggaaaa acaaaaaagc cttttatcct
    88801 ttctagaaga aaagagataa aaggtttctt tgtttataaa attttgtctg ctatattata
    88861 agttaattaa ataaatgtgt tctattgata aaggacattc aaatcccttt ccttttggaa
    88921 tccttctttt ttacatcagt ttgattttcg tatagtattc tttctcatct tcacgataaa
    88981 tcgcagcccc atttttttgt tgtgctttaa gactgccaag atttttttta tttacagaca
    89041 aaagtgcctc atcaatgccg attttttttg cctcttgtag tactaatgct aatccttgtg
    89101 tggcatatcc ttttttacga taattagggg agatgccgta accaatatgg ccagcgccgt
    89161 ttcttaatgt ttcgttcagt ttatggcgca aattaaaaat tcctacatac tcatgttcat
    89221 cactttctaa aataaagacg gttgcgggaa cgtaactctc aggaagatcg attcctaaag
    89281 acgttttttc gcattttttt acataatcta aaaattcagc aaatgtatag ccataagcat
    89341 tgttgataaa tccactctca tttggtccaa agctagtttg tagctgataa gctttcttta
    89401 aatctgcttc ccatagtttg atcagtttca tcgtattcac ctctttaagt aaccttattc
    89461 atttgttttc tactatagca ctattgttgt aaatagccat gcctattttt atttattgtg
    89521 tcatatcgta ttaagaatca tcgaacaata caaatatgaa ttacaataaa aaaattattt
    89581 gaagttcgtt cattcgttac ttatgatctc tagaagaaag aaaacgtgaa ttacttcagc
    89641 gtctagaatt ccagaaggat agtaatcaac agaagaaata atcaatatcc aaatgaaaga
    89701 agatagctga atcgagaaaa agaggaaaaa agaaatgaag aaaaaaataa aatagttact
    89761 aatcccagag tcgttcgttt aacattgaaa tcgatcatat ggataaaaca gattttttca
    89821 ccaaccctca atagatgatg gagttgctcg gatgaattat ttgtgtagat ggcataaggg
    89881 agggcgtaca gaaatgaaaa agaacaaaaa tatgttcttg acaaaaaaca catgtaatcc
    89941 taaactaaaa gatgtgatgc ggctatggcg gaattggcag acgcgctagc ttcaggcgct
    90001 agtgagggtg acctcgtgga agttcgagtc ttcttagccg cataatttgt ttttttataa
    90061 agagaaggta cacctggagc gatgagaaag aaaataacat attatctaaa agaatatagg
    90121 aaaaatttta aacaacggaa ccagattcaa ataaatcaaa aaaaatttgt gtgaaggtgg
    90181 gacagtttaa aacctaatag attgattcaa atagtagatt tatagattct gatacaagaa
    90241 atactggcaa acgatagtta aggaataaag actaaactta aactcaaaaa gaggtcatgc
    90301 gaaagaataa atcgcatgac ctcttactat attttgaatg tgtttaaacg ttcaaataat
    90361 gaatcttagt accaaccgtt tgcttcccag aatgctttcg ccgcttccca agaaccataa
    90421 cgtgaagtaa catattgttc tgctactctt tcttggtttg cagcagagta gtcaccattt
    90481 aagtaagaag aatctaattg gtaacggccg atgtaacgtc cgttcgttgc tgtgtaagaa
    90541 ccgcttgatt ctttttgtgc gatccattct tttgcagagc ttgtacttgc tggagtagca
    90601 gcagtttctg ttacagcagg agcaggttgt gtttcagcaa caggcgctgc ttgtgtttcc
    90661 gtttgaaccg tttcttgtac aacaggttgt tcagcttgaa caggttcagc ttggactggt
    90721 gcttcttgaa cggctgcttg aggttcagca gctgcttgtg cagagccttc tgttgggatt
    90781 gttaattgtt gtcctgagta gatcaggtta atatcagaaa ttgaatttga ttctgcaatg
    90841 gcattgatca aggagttatc accaacgtat ttttgagaaa tcgttgatag agtatcacct
    90901 gattgaacgg tataagcttc gtccgcatga gcagtcgttc ccatgaagaa tgcagcgccg
    90961 gcagccaaag ttgttccaaa aagtaaagtt ttaagtgatg tcatgaaaaa tctcctttat
    91021 tcgttaaaaa gttttatttg ttgtgttcaa cgaggaatac tttaacacgt gaaaatattt
    91081 cataggtaaa agaagcatga caatttatga caaatccacg ttttttgtaa cagaatgatg
    91141 ttcgctcgat gtgaaaaatg atgaggaatt tcacataatg cagaaataat gggattagaa
    91201 caggtgttct gatgagaaaa gaaatgtata aataacttga aagaaattgc ttttgttcat
    91261 cattttattt acatattgcg tatatttttt gtatttttgc ttgagatgtt acaataaaag
    91321 aaaaaggagg cggttccaat gagtaaaaga taccagaaca tcatggtagc agttgacgga
    91381 tcaagacaat cgatcaaagc gttcgctgaa gcccttgact tagcaaagga caatgaagcc
    91441 cacttattta tcgtgtcaat catcaacaaa gttgagctga cccatagtgc ctatgccttt
    91501 tcaaaaatct atgcagatga aaaacaaaga acagaagtag ccatgctgaa aaaaatcaat
    91561 gatgccaaag agtacggcat tgctgagatc cacgcaatag ttgaaactgg agatccaaga
    91621 aatttgattg ccaatgtcat ccctggacaa gaaaatattg atttgatcgt tatgggagcg
    91681 acaggaaaag gtgctataca acaagcatta gttggatcga ccgcttctta tgtcgtatca
    91741 catgcccctt gcagtgtgtt ggtcgtgaag taatgagata agggaggaat agaaaatggt
    91801 tcgtcctcaa gaagtccgtg cgccaaaaga aaaaatagaa attttagcaa ttattgaaga
    91861 cggcacacaa acaaagaagg gatactcgat cgctttagta aagtggaaag gaaaaaaagg
    91921 tgttgctctg agatgggatg gagataacca acaagataaa ggattccctg tcacagctaa
    91981 cggttatcat ccagcgtggt ttgttctgcc tgataaattt atggaattat acagctatga
    92041 ttatgcaaga gccgcagcat caatcaaagc attagataaa ttaacagaag agcagaatga
    92101 aatggaggaa aaataaaaaa gacgaaccaa tcagccttta gaaaactgat tagttcgagg
    92161 agtaaaaatg aaaaaaggtt atttgggatg aaactagaat aatgcgtata acttaaataa
    92221 aacttaaagc aataaaatgg caagagggtg aggcaaatgg aagcaggaaa agtattacag
    92281 gaagtaaaag cactatgtgc agataaaaaa tatgaagaag cgaaaagcct gatcgaaaag
    92341 aacaaagaaa atttggaaga aaagtacccg atcgcacaag aatttataga attaaaacaa
    92401 ggaacgatcc ttcaccgatt caaacatttt tttggtataa cagaatagaa aaaacgatta
    92461 aagatcggca gaaatttgct gcatctttaa tcgttttctt tttaaacatg cgagggattc
    92521 aattctgatt cttatataaa aaatagatcc aaataataag aaaaattact gaaagcgtca
    92581 attcgatgat gtgtgttatt aatacagacg ttgtttccca atgcctaaaa gaaaaaattt
    92641 gataagtaaa atatacagca ggtaaagagg ccagtaaaac tgaaaacttc ttttttgtcc
    92701 attttatgta atagaaaaga atgcttatca taataaaaaa aggaatataa aaaacaaatt
    92761 gaccgatcgc gatcatacta ttgcctccga taaataaagt ccatgataca aaataacact
    92821 ttgtgcgaaa tggcgcaagc agttttgtgg atttatccgg taaaatctgt atcgattttg
    92881 aaattagagg agaaacttgc tataatcaaa gtgaaagaag gagtgggatt ttcatggatc
    92941 atgtagtgtt agaaatcgat ttgcatttga tcaataatat tcgggtgatt tactatgttg
    93001 taagtaacag tgtcgaacaa cgtgtactga cgaataaaat aaatggtatt ttagcaaaga
    93061 aagacgttca ccgattcaat aatggtgaag gaagttatta tagtatccca gtagaaaaaa
    93121 ttatttatac gacagtcaaa gtcagagaag atctagatac caaaaaagca tatgaaccta
    93181 tttttacaac ttattgattg acagcagatg gaggaaaaaa atgaatccat atgaacaact
    93241 tattcaagat ttgatcgatg gaaaaatcga aaagattgat gtaaaaagag aagaattaat
    93301 ggcttttcga gaagcgtggc tgaagttgga gaatcgtaaa tatgtggtgg gaaaagcctc
    93361 actgaacggc aatgtgactt atcattacga tccgacacgt ttattttagt atgaagtatt
    93421 cagaaaagaa ccaaaggagg acgatgcagc agcattgtcc tcctttgatt ttacaaaagt
    93481 gaaagtttta cttatttgaa tagattttta aatttgtttt tgacactgtc gatatttaca
    93541 tcttttaaaa gattttgggc tttctcttta taaggtccta attgttcttt atgttcttcg
    93601 ataaatcgtt ttgcgccatc gaaattgccg ttcttaatca tttccttgac tttttgaaat
    93661 aattcttctt gattcatttt gaacacatcc tttgctatca acatgatttt ttacatggac
    93721 aaaacgagaa aaactgattt atccacacgt caataatatc aaataacgat catttttact
    93781 aaaaaaacac tcgattctcg cttctaaagt aggagaaaaa tctccaactt gggacggatg
    93841 gaatttcttt aactgaccca tatactgaat atataacaag gaggtagaaa gatgaaagtg
    93901 attaaatatt tgattggact ggcggcgatt agtggtattt tgctatttgg actgaaatat
    93961 tatactgaag gaagttatgg agaaatccct ggtatacttg atcagctaaa tccattagtt
    94021 gaaaaaggag aggtctatgt aaagacacaa aaaccagagg aagtaaatga atatggtaca
    94081 gcaaggtatg tgcagaaagc tgctgatgcc aatgggaaag aacgaacggt tgaatttaat
    94141 ggtctttctg tgttaaaaga aaatcattat ttgaaaatta gcaataaagg agcacacata
    94201 gaaacgtatg aggaagttcc tagagaaaaa gttccggaga aagcattagc aattattggg
    94261 taaatcagtt tttgtattaa gaatacgccc gattttatta ttcataattt aattatgtaa
    94321 actaaataca agtagtaaaa ataatacaat aatccccctg caaaaagatt gttcttttac
    94381 agggggttca ttttttcagc aagcacatca aattgggatg gcagggttcg aacctacaat
    94441 tgcttgattc agagtcaagt gccttaccag tttggctaca tcccatttat tcaacaaaat
    94501 aatcatagca ctttcctaaa aaaacgcaag ttatttttct tgatcggata gttgttgctt
    94561 tactcgtaaa aggcggcgta ctagtttctt ttctaatcca gcaggaaggg caatcagttc
    94621 tgctactgac aagacggtgt ccaataactg atattctttg acaggttcat tcataatatg
    94681 atagatgttt gctaaacgtt caatatattc aaagcgagta tactctgttc gagcaattag
    94741 aaatttcaat aaatcggtgg ctttctcgta ctcttgatct gcgtaataaa caagagattg
    94801 acgatacaat ttgatttcca gttcattgag ggtagcaggt ctgcgacgct cgttccactc
    94861 attaatagag actttacctt gaacatttcc cttgcagtca cggacaaaaa taatcggaat
    94921 ttcatttgga tccatttttt tatgtgtgaa tttttccatt atctacgctc ccttcaaagg
    94981 tttggtatct tgagtataag ggatttttgt ttgaattact agcttttctc caaagttagc
    95041 atctgtccac ccattgcagt gaaaatcgcc gaaaaatcgt tgatcggtac tgctcgattt
    95101 tttacaccat agggatcgtt gacataaata ttttctttgt catatccagt gactacacaa
    95161 gcatgaacaa gaggagtgac tcttacttct ccattatttg tggtccaagt cataaaatca
    95221 gtttcatctg ggacttcaaa attgatagtc acagaagtcc agacaggatt tcctttagat
    95281 agtgcttttt tgatatcatc gagttgagca tcggtttttg gaaaagtgtg ataatccgtt
    95341 tggacgattt gctgagcaag ggaggcaact gggggaacat agacgaccat agcccagtct
    95401 ccgccactga tatcaccaac aaatccttca ttaggatcgc catgagtccc atctgcattg
    95461 aaaacaggga cgtaatccaa ttgctcagct aactggtttt tagttgtttc ataaccataa
    95521 aaagataaaa gcatagaaag cgaagtgact tcacagccat tttctaaaga aggagaatca
    95581 aactggctct ctaatggaac atctagtaaa acttctgctt tctcttttgt ctttttcgtt
    95641 ttttgtgttg aacttttttg tgcagtgttc attgtatgtt ctggagaatg gatatgtagg
    95701 taataacttg taccgcttaa taaaagagca gctgtgcccc ctagaaacaa tagttttttg
    95761 aacgtttttt tcttcatttg aaatctccct tttcagctgt ttatctttcc tattataaat
    95821 gtatttttat tggaaatgga agtattatat tttaatatgt aggaaataat tagtttttaa
    95881 ggaatatgtt ttaatttttt gaaaaaaatt cttctaaata caacagctgt tttaattgtg
    95941 aaaacgaaaa cagtacgcta taatgcctgt aaggttgatt tttaactgta aataaaaatc
    96001 aatgagttaa atctccaaag aaatagcagt ggtaatgtgg agaaaagttc cagcagttta
    96061 ggaggatttt gatgacggaa gaaatgatta atttaggaga acaatatgca tgcaaaccaa
    96121 ttggttttac aaaaacggtc attggtgaag ttgtatcaaa aatgacaaac tgcgccgtgg
    96181 tcaaagttgc ccaatgtgct gcagaggacc aagaattatt agatgaaaaa gcaagcatgg
    96241 ttgttgcaaa atatgataca tttgaataaa gaaaacaatt ggacgtgcgg cgtgctgcaa
    96301 gtccaatttc tttgagaagg taaatcagta ttcttttcct attttctgga gaagaaaaag
    96361 cgaggcgagt tgtcatggta acattcttta cggttctatt gtttttattc gttgttgtga
    96421 tgtttttatt tctttggctg gttcgaaaag aaattattta tcggactgtg cgaaatcgat
    96481 gggtctactt ggtgataccc ttcttagtgt cactagtcat ttggtataca ctcatcagtc
    96541 atcctacagc agatgaattg gcaaaaggga tcttgtcagc aatgattttt attagttttt
    96601 tgttggacag tagaggaatc acagaagaag gacttgtttt gaatagcttt gacaaaaaag
    96661 gtgttccttt ttctgagatc aataaaattg tattatatca gccaaaaggt tctaaaatcg
    96721 taaaaatgaa ttttttccga aacggatggc gaggaccgat gctgaaattt tctgcatcat
    96781 tagaagaatt agttccattt ttgtcccaac gcttaaacga tgaggcagag attgatatta
    96841 tgattgatcc agaataaaaa cagaggttgc gacaagatgt ttgtcacaac ctctgttttt
    96901 tatttcaaat aaaattatcc aaatacgcgg aagcgatcgg catcgttcat gtattctttt
    96961 tccccagccg gtgtttctgg tgaaccgaat actaattgcg aacgtagttt ccagtttgaa
    97021 gggatattcc attcttttgc aactgcttcg tcaataactg ggttgtaatg ttgcaagttt
    97081 gcgcccaatc ctttatcaac taatgctacc caagtattag ctgttgcgat tccgtttgat
    97141 tgttctgacc aatctgggaa gttgtctgca tataattcaa attgttcttg tagacctttt
    97201 accacgtcag tatctttgaa gaataatact gtaccataac catttttgaa accagctaat
    97261 ttgttttgtg tatttgggaa agcttctgct ggagtcaatg ggcgaagtgc ttcttcagtg
    97321 atttcccaaa gtttttcatg tgcatctccg aaaaggataa ctgcgcgtgt tgattgagca
    97381 ttgaaagcag ttgggctttc tttaattgct tctttgatca aagttgttaa ttcttcatta
    97441 gaaagtgaaa cattacgtcc tagatgatag attgaacggc ggtttttcaa agtgtcagta
    97501 aaagttgtca taataaaatt tctcctttga tttgcgtttt gcattttttt aattgattac
    97561 gaaatgaagt atagcacctt acaaaaagta agtaaacaga tatgctcaca aaaaataagc
    97621 gaagttcaaa aaacaatttt aataagaaaa atcgttatgt aaggattttc ttagttatcg
    97681 ctttcattgt tgtgttttag gaatttttgc ttatttgaaa aaaacagctg atatataatt
    97741 attaaatctc tatcttcttt tttttatgat attgccatta aaaattactt gcttttatag
    97801 aaaattagtt tatatttctt aaataagttt tttagttaaa tttttcggta aagatgtata
    97861 atattttctg aaaatttaaa gaattggggt atagattatg gaaaaacagc aagacaaggg
    97921 cttcttcggg cagccgaagg gattgtcaac tttgttcttc actgagatgt gggaacgatt
    97981 tagttattac ggtatgcgtg cattacttat ctattatatg tacgatacag ttgccaacgg
    98041 gggacttgga ttaccacgag caacagcatt agctatcatg tcgatctacg gatctttgat
    98101 ctacatgtct agtatcgtcg gcggatgggt atctgaccga gtgttaggag caaaacgcac
    98161 tgtattcttc ggtggagttt tcattatgct tggccacatc gtcttggctt taccatttgg
    98221 tgtaagtaca ttgtttgttt cgatggcatt gattattatc ggaaccgcct ttttgaaacc
    98281 aaatgtttct ggcatggtcg gacatcttta ttcaaagact gacttgcgaa gagatgcagg
    98341 attttcgatt ttttacatgg gtgtcaactt aggggcatta ttagcaccac taatcgttgg
    98401 tacaatcggt caagaatata actatcattt agggttctct ttagctgcta ttgggatgtt
    98461 ctttggatta ttacaataca tcatccaagg acgcaagaca ttagacggag tgggtacaac
    98521 accgccgaat cctttgacaa ctgaagaacg taaaggattc atccgtaact tgatcatcgc
    98581 acttgttgtt atcgctgcag tattcggcgg ggcacaacta actggtcatc tgacaattga
    98641 cttttttgtc aatacaatca gtgtattggg gattatctta ccgttgtatt actttatcaa
    98701 aatgctgact tcaaaagatg taactgctga agaaaaacca agagtatggg cttatatccc
    98761 attattcctt gcagcaatca ttttctggtc attacaagaa caaggttcat ctatcttagc
    98821 tttatttgct agtgaacgta cacaatctac gctatttggt gtaacgatcc aagcaagctg
    98881 gtatcaatca ttgaatccaa ttttcatctt tattctgaca ccagtattcg taacgatgtg
    98941 gacgaaactt ggtgaacgtc aaccatctac agtagtgaaa ttctctcttg gacttttatt
    99001 tgcaggatta tcgtacttgc tattgatgtt gccgggtatg ctttatggta caagtggaaa
    99061 agtaagtcca ttgtggttgt tgggaagttt cttcatcgtg gttattgctg aattgtgtct
    99121 ttcaccagtt ggtttgtctg tgacaacaaa attagcacca cgagcatttg aatcacaaac
    99181 aatcgctatt tggttcttag ctgatgcttc ttcacaagca atcaatgcac aaattgcacg
    99241 cttctacaca ccgggaacag aatctgctta cttcggtatt atcggtgcag tagcaatcgt
    99301 cggtggtatc ttgctattta ctgtgaaaga accaatcaaa aaactaatgg gctctattca
    99361 ttaatcaatg aacataaaaa caggaattgc ttatttgcag cagttcc
//
LOCUS       DASHWW010000003        93450 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.003, whole genome shotgun sequence.
ACCESSION   DASHWW010000003 DASHWW010000000
VERSION     DASHWW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 93450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.003"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            83..970
                     /locus_tag="U2R64_000238"
     CDS             83..970
                     /locus_tag="U2R64_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEM8917088.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="U2R64_000239"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="U2R64_000239"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEM8917089.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="U2R64_000240"
     CDS             2272..2718
                     /locus_tag="U2R64_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEM8917090.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="U2R64_000241"
     CDS             2991..4343
                     /locus_tag="U2R64_000241"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HEM8917091.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="U2R64_000242"
     CDS             4514..4801
                     /locus_tag="U2R64_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917092.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5027..5470
                     /locus_tag="U2R64_000243"
     CDS             5027..5470
                     /locus_tag="U2R64_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8917093.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5476..6660)
                     /locus_tag="U2R64_000244"
     CDS             complement(5476..6660)
                     /locus_tag="U2R64_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HEM8917094.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6928..7626
                     /locus_tag="U2R64_000245"
     CDS             6928..7626
                     /locus_tag="U2R64_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEM8917095.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7633..8310
                     /gene="nth"
                     /locus_tag="U2R64_000246"
     CDS             7633..8310
                     /gene="nth"
                     /locus_tag="U2R64_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEM8917096.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8436..8969)
                     /locus_tag="U2R64_000247"
     CDS             complement(8436..8969)
                     /locus_tag="U2R64_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917097.1"
                     /translation="MVLNIFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9266..11647)
                     /locus_tag="U2R64_000248"
     CDS             complement(9266..11647)
                     /locus_tag="U2R64_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEM8917098.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11637..12284)
                     /gene="recU"
                     /locus_tag="U2R64_000249"
     CDS             complement(11637..12284)
                     /gene="recU"
                     /locus_tag="U2R64_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEM8917099.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12348..12887
                     /locus_tag="U2R64_000250"
     CDS             12348..12887
                     /locus_tag="U2R64_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEM8917100.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12977..13396
                     /gene="gpsB"
                     /locus_tag="U2R64_000251"
     CDS             12977..13396
                     /gene="gpsB"
                     /locus_tag="U2R64_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEM8917101.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13418..13785
                     /gene="rnpB"
                     /locus_tag="U2R64_000252"
     ncRNA           13418..13785
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="U2R64_000252"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13994..15160
                     /locus_tag="U2R64_000253"
     CDS             13994..15160
                     /locus_tag="U2R64_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEM8917102.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15206..16702
                     /locus_tag="U2R64_000254"
     CDS             15206..16702
                     /locus_tag="U2R64_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HEM8917103.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16783..17466
                     /locus_tag="U2R64_000255"
     CDS             16783..17466
                     /locus_tag="U2R64_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8917104.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18111..19301
                     /locus_tag="U2R64_000256"
     CDS             18111..19301
                     /locus_tag="U2R64_000256"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HEM8917105.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19403..20356
                     /locus_tag="U2R64_000257"
     CDS             19403..20356
                     /locus_tag="U2R64_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HEM8917106.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20425..21774
                     /locus_tag="U2R64_000258"
     CDS             20425..21774
                     /locus_tag="U2R64_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8917107.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21957..22280)
                     /locus_tag="U2R64_000259"
     CDS             complement(21957..22280)
                     /locus_tag="U2R64_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917108.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22409..23572
                     /locus_tag="U2R64_000260"
     CDS             22409..23572
                     /locus_tag="U2R64_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEM8917109.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23642..24991
                     /locus_tag="U2R64_000261"
     CDS             23642..24991
                     /locus_tag="U2R64_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEM8917110.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25036..25467)
                     /locus_tag="U2R64_000262"
     CDS             complement(25036..25467)
                     /locus_tag="U2R64_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917111.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25855..28497
                     /gene="alaS"
                     /locus_tag="U2R64_000263"
     CDS             25855..28497
                     /gene="alaS"
                     /locus_tag="U2R64_000263"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEM8917112.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28697..29293
                     /locus_tag="U2R64_000264"
     CDS             28697..29293
                     /locus_tag="U2R64_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8917113.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29415..30563
                     /locus_tag="U2R64_000265"
     CDS             29415..30563
                     /locus_tag="U2R64_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEM8917114.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30601..31014)
                     /locus_tag="U2R64_000266"
     CDS             complement(30601..31014)
                     /locus_tag="U2R64_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HEM8917115.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31093..31524
                     /locus_tag="U2R64_000267"
     CDS             31093..31524
                     /locus_tag="U2R64_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEM8917116.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31623..31856)
                     /locus_tag="U2R64_000268"
     CDS             complement(31623..31856)
                     /locus_tag="U2R64_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HEM8917117.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHQ"
     gene            32039..33709
                     /locus_tag="U2R64_000269"
     CDS             32039..33709
                     /locus_tag="U2R64_000269"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEM8917118.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33856..34242
                     /locus_tag="U2R64_000270"
     CDS             33856..34242
                     /locus_tag="U2R64_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917119.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34229..34927
                     /locus_tag="U2R64_000271"
     CDS             34229..34927
                     /locus_tag="U2R64_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8917120.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34932..35396
                     /locus_tag="U2R64_000272"
     CDS             34932..35396
                     /locus_tag="U2R64_000272"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEM8917121.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35393..36304
                     /locus_tag="U2R64_000273"
     CDS             35393..36304
                     /locus_tag="U2R64_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEM8917122.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36539..37078
                     /gene="pyrR"
                     /locus_tag="U2R64_000274"
     CDS             36539..37078
                     /gene="pyrR"
                     /locus_tag="U2R64_000274"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEM8917123.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37092..38375
                     /locus_tag="U2R64_000275"
     CDS             37092..38375
                     /locus_tag="U2R64_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEM8917124.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38388..39314
                     /locus_tag="U2R64_000276"
     CDS             38388..39314
                     /locus_tag="U2R64_000276"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEM8917125.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39333..40613
                     /locus_tag="U2R64_000277"
     CDS             39333..40613
                     /locus_tag="U2R64_000277"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEM8917126.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40618..41694
                     /gene="carA"
                     /locus_tag="U2R64_000278"
     CDS             40618..41694
                     /gene="carA"
                     /locus_tag="U2R64_000278"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEM8917127.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41699..44884
                     /gene="carB"
                     /locus_tag="U2R64_000279"
     CDS             41699..44884
                     /gene="carB"
                     /locus_tag="U2R64_000279"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEM8917128.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44938..45714
                     /locus_tag="U2R64_000280"
     CDS             44938..45714
                     /locus_tag="U2R64_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEM8917129.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45711..46643
                     /locus_tag="U2R64_000281"
     CDS             45711..46643
                     /locus_tag="U2R64_000281"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEM8917130.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46640..47356
                     /gene="pyrF"
                     /locus_tag="U2R64_000282"
     CDS             46640..47356
                     /gene="pyrF"
                     /locus_tag="U2R64_000282"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEM8917131.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAAGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47363..47992
                     /locus_tag="U2R64_000283"
     CDS             47363..47992
                     /locus_tag="U2R64_000283"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEM8917132.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47980..48294
                     /locus_tag="U2R64_000284"
     CDS             47980..48294
                     /locus_tag="U2R64_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917133.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48332..48973
                     /locus_tag="U2R64_000285"
     CDS             48332..48973
                     /locus_tag="U2R64_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8917134.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49016..49708
                     /locus_tag="U2R64_000286"
     CDS             49016..49708
                     /locus_tag="U2R64_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HEM8917135.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49705..50607
                     /locus_tag="U2R64_000287"
     CDS             49705..50607
                     /locus_tag="U2R64_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8917136.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="U2R64_000288"
     CDS             complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="U2R64_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HEM8917137.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52661..53284
                     /locus_tag="U2R64_000289"
     CDS             52661..53284
                     /locus_tag="U2R64_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917138.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53734..54783
                     /locus_tag="U2R64_000290"
     CDS             53734..54783
                     /locus_tag="U2R64_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8917139.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54780..55661
                     /locus_tag="U2R64_000291"
     CDS             54780..55661
                     /locus_tag="U2R64_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917140.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55664..56434
                     /locus_tag="U2R64_000292"
     CDS             55664..56434
                     /locus_tag="U2R64_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8917141.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56713..57567
                     /gene="aroE"
                     /locus_tag="U2R64_000293"
     CDS             56713..57567
                     /gene="aroE"
                     /locus_tag="U2R64_000293"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEM8917142.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57745..58908
                     /locus_tag="U2R64_000294"
     CDS             57745..58908
                     /locus_tag="U2R64_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8917143.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59025..59435
                     /locus_tag="U2R64_000295"
     CDS             59025..59435
                     /locus_tag="U2R64_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8917144.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59609..61837
                     /gene="topB"
                     /locus_tag="U2R64_000296"
     CDS             59609..61837
                     /gene="topB"
                     /locus_tag="U2R64_000296"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEM8917145.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62008..62292
                     /locus_tag="U2R64_000297"
     CDS             62008..62292
                     /locus_tag="U2R64_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917146.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62452..62688
                     /locus_tag="U2R64_000298"
     CDS             62452..62688
                     /locus_tag="U2R64_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8917147.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62685..63083
                     /locus_tag="U2R64_000299"
     CDS             62685..63083
                     /locus_tag="U2R64_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEM8917148.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63750..64694)
                     /locus_tag="U2R64_000300"
     CDS             complement(63750..64694)
                     /locus_tag="U2R64_000300"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEM8917149.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64990..65934)
                     /locus_tag="U2R64_000301"
     CDS             complement(64990..65934)
                     /locus_tag="U2R64_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917150.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66155..67369
                     /locus_tag="U2R64_000302"
     CDS             66155..67369
                     /locus_tag="U2R64_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8917151.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67391..69406
                     /locus_tag="U2R64_000303"
     CDS             67391..69406
                     /locus_tag="U2R64_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HEM8917152.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69489..70862)
                     /locus_tag="U2R64_000304"
     CDS             complement(69489..70862)
                     /locus_tag="U2R64_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEM8917153.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70888..71172)
                     /locus_tag="U2R64_000305"
     CDS             complement(70888..71172)
                     /locus_tag="U2R64_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8917154.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71174..73189)
                     /locus_tag="U2R64_000306"
     CDS             complement(71174..73189)
                     /locus_tag="U2R64_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8917155.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRRGAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73368..73673)
                     /locus_tag="U2R64_000307"
     CDS             complement(73368..73673)
                     /locus_tag="U2R64_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HEM8917156.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73762..74793)
                     /locus_tag="U2R64_000308"
     CDS             complement(73762..74793)
                     /locus_tag="U2R64_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8917157.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75000..75875
                     /locus_tag="U2R64_000309"
     CDS             75000..75875
                     /locus_tag="U2R64_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8917158.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76027..76869)
                     /locus_tag="U2R64_000310"
     CDS             complement(76027..76869)
                     /locus_tag="U2R64_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8917159.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76961..78838)
                     /locus_tag="U2R64_000311"
     CDS             complement(76961..78838)
                     /locus_tag="U2R64_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8917160.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78835..80256)
                     /locus_tag="U2R64_000312"
     CDS             complement(78835..80256)
                     /locus_tag="U2R64_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8917161.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80259..83648)
                     /locus_tag="U2R64_000313"
     CDS             complement(80259..83648)
                     /locus_tag="U2R64_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEM8917162.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83905..85295
                     /locus_tag="U2R64_000314"
                     /pseudo
     CDS             83905..85295
                     /locus_tag="U2R64_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(85368..86015)
                     /locus_tag="U2R64_000315"
     CDS             complement(85368..86015)
                     /locus_tag="U2R64_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEM8917163.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(86023..86709)
                     /locus_tag="U2R64_000316"
     CDS             complement(86023..86709)
                     /locus_tag="U2R64_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917164.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(86715..87788)
                     /locus_tag="U2R64_000317"
     CDS             complement(86715..87788)
                     /locus_tag="U2R64_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917165.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            88010..88684
                     /locus_tag="U2R64_000318"
     CDS             88010..88684
                     /locus_tag="U2R64_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8917166.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            88689..90029
                     /locus_tag="U2R64_000319"
     CDS             88689..90029
                     /locus_tag="U2R64_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8917167.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(90178..91164)
                     /locus_tag="U2R64_000320"
     CDS             complement(90178..91164)
                     /locus_tag="U2R64_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HEM8917168.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            91888..92919
                     /locus_tag="U2R64_000321"
     CDS             91888..92919
                     /locus_tag="U2R64_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8917169.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            93028..>93450
                     /locus_tag="U2R64_000322"
     CDS             93028..>93450
                     /locus_tag="U2R64_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEM8917170.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        29893 a        16575 c        18964 g        28018 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa
     4981 taggaaacaa aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca
     5041 actgctaata gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga
     5101 aatggaaaaa gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg
     5161 gaaaatccct gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc
     5221 catcagtaag ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga
     5281 agagaataaa aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag
     5341 acacgagcaa ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc
     5401 aaaagaagaa tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag
     5461 tagcaaatga agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa
     5521 tccgaatacc gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc
     5581 gatgacgcgc gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt
     5641 atctgagaca gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa
     5701 accataacag ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt
     5761 gatgaataga taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga
     5821 aaattttttg agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat
     5881 caaagagaag cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg
     5941 agaaaagata gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa
     6001 aggaataacg gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga
     6061 gaaacttaaa tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc
     6121 ataaacggca tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa
     6181 ctcagctaat agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc
     6241 catccatcca aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata
     6301 taaggtggag atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca
     6361 tatcgaattt cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat
     6421 aaggatcgga tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa
     6481 ggcagctaga gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga
     6541 gtgagaataa ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc
     6601 agtgaataag acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat
     6661 gtaaaaactc ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt
     6721 gtttccttgt caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag
     6781 tgaagatacg catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg
     6841 accgatcagt gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt
     6901 atactgtgat tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga
     6961 caaacagtca tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa
     7021 gaatttttat ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat
     7081 ttgcagatga ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat
     7141 cgtctcgtaa caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca
     7201 gatcgatata atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa
     7261 aaaaaatacg aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa
     7321 caagaatttg gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa
     7381 gaagaccatt atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag
     7441 gcttatagtt ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt
     7501 acaaaacaac aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa
     7561 gtagaacagt cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag
     7621 gagtagcgga atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga
     7681 atgtttcccg aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca
     7741 gtgatcttaa gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt
     7801 gcctcttttc cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa
     7861 ataaaaacga ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag
     7921 ctgattgaac gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct
     7981 ggtgtaggca gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc
     8041 gcagtagata cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct
     8101 acggtcatgg aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag
     8161 acacatcata cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc
     8221 gaggtatgtc ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa
     8281 aaggcgctaa aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta
     8341 tgaattatct tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt
     8401 aaatgtacat actcagtagc taggatggta acttattaca atttattgcg ataaaaataa
     8461 aagttgttat ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct
     8521 ataaaataag tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt
     8581 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
     8641 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
     8701 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
     8761 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
     8821 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
     8881 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
     8941 ccttctttca aaaaaatatt caaaaccata tattgtattt tttatttgat aataacaatg
     9001 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
     9061 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
     9121 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
     9181 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
     9241 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
     9301 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
     9361 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
     9421 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
     9481 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
     9541 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     9601 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     9661 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     9721 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     9781 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     9841 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     9901 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     9961 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
    10021 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
    10081 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
    10141 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
    10201 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
    10261 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
    10321 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
    10381 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
    10441 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
    10501 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
    10561 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
    10621 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
    10681 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
    10741 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
    10801 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
    10861 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
    10921 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
    10981 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
    11041 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
    11101 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
    11161 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
    11221 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
    11281 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
    11341 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
    11401 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
    11461 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
    11521 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
    11581 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
    11641 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
    11701 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
    11761 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
    11821 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
    11881 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
    11941 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
    12001 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
    12061 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
    12121 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
    12181 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
    12241 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
    12301 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
    12361 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
    12421 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
    12481 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
    12541 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
    12601 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
    12661 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
    12721 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
    12781 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
    12841 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
    12901 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
    12961 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
    13021 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
    13081 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
    13141 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
    13201 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
    13261 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
    13321 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
    13381 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
    13441 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
    13501 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
    13561 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
    13621 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
    13681 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
    13741 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
    13801 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
    13861 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
    13921 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
    13981 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
    14041 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
    14101 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
    14161 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
    14221 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
    14281 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
    14341 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
    14401 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
    14461 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
    14521 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
    14581 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
    14641 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
    14701 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
    14761 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
    14821 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
    14881 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
    14941 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
    15001 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
    15061 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
    15121 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
    15181 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
    15241 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
    15301 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
    15361 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
    15421 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
    15481 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
    15541 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
    15601 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
    15661 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
    15721 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
    15781 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
    15841 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
    15901 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
    15961 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
    16021 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
    16081 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
    16141 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
    16201 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
    16261 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
    16321 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
    16381 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
    16441 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
    16501 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
    16561 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
    16621 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
    16681 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
    16741 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
    16801 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
    16861 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
    16921 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
    16981 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
    17041 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
    17101 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
    17161 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
    17221 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
    17281 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
    17341 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
    17401 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
    17461 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
    17521 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
    17581 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
    17641 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
    17701 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
    17761 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
    17821 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
    17881 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
    17941 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
    18001 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
    18061 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
    18121 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
    18181 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
    18241 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
    18301 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
    18361 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
    18421 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
    18481 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
    18541 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
    18601 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
    18661 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
    18721 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
    18781 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
    18841 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
    18901 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    18961 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    19021 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    19081 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    19141 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    19201 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    19261 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    19321 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    19381 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    19441 tggttcagag ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac
    19501 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    19561 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    19621 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    19681 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    19741 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    19801 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    19861 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    19921 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    19981 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    20041 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    20101 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    20161 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    20221 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    20281 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    20341 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    20401 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    20461 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    20521 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    20581 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    20641 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    20701 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    20761 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    20821 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    20881 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    20941 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    21001 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    21061 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    21121 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    21181 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    21241 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    21301 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    21361 ggaatgcgtc tcccttatgt tatggcaaaa gaaaacaacc tgccttttag caagctcttt
    21421 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    21481 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    21541 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    21601 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    21661 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    21721 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    21781 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    21841 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    21901 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    21961 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    22021 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    22081 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    22141 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    22201 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    22261 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    22321 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    22381 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    22441 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    22501 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    22561 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    22621 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    22681 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    22741 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    22801 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    22861 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    22921 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    22981 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    23041 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    23101 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    23161 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    23221 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    23281 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    23341 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    23401 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    23461 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    23521 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    23581 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    23641 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    23701 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    23761 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    23821 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    23881 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    23941 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    24001 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    24061 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    24121 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    24181 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    24241 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    24301 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    24361 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    24421 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    24481 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    24541 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    24601 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    24661 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    24721 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    24781 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    24841 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    24901 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    24961 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    25021 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    25081 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    25141 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    25201 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    25261 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    25321 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    25381 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    25441 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25501 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25561 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaaataa gtacgaaaag
    25621 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25681 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25741 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25801 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25861 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    25921 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25981 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    26041 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    26101 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    26161 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26221 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26281 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26341 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26401 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26461 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26521 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26581 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26641 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26701 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26761 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26821 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26881 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26941 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    27001 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    27061 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    27121 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27181 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27241 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27301 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27361 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27421 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27481 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27541 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27601 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27661 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27721 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27781 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27841 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27901 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27961 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    28021 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    28081 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    28141 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28201 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28261 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28321 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28381 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28441 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28501 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28561 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28621 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28681 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28741 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28801 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28861 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28921 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28981 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    29041 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    29101 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    29161 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29221 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29281 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29341 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29401 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29461 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29521 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29581 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29641 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29701 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29761 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29821 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29881 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29941 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    30001 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    30061 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    30121 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30181 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30241 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30301 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30361 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30421 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30481 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30541 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30601 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30661 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30721 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30781 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30841 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30901 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30961 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    31021 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    31081 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    31141 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31201 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31261 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31321 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31381 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31441 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31501 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31561 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31621 atctattgat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31681 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31741 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31801 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31861 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31921 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31981 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    32041 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    32101 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    32161 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32221 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32281 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32341 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32401 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32461 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32521 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32581 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32641 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32701 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32761 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32821 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32881 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32941 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    33001 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    33061 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    33121 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33181 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33241 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33301 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33361 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33421 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33481 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33541 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33601 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33661 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33721 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33781 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33841 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33901 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33961 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    34021 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    34081 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    34141 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34201 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34261 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34321 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34381 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34441 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34501 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34561 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34621 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34681 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34741 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34801 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34861 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34921 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34981 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    35041 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    35101 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    35161 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35221 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35281 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35341 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35401 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35461 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35521 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35581 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35641 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35701 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35761 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35821 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35881 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35941 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    36001 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    36061 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    36121 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36181 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36241 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36301 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36361 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36421 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36481 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36541 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36601 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36661 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36721 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36781 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36841 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36901 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36961 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    37021 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    37081 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    37141 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37201 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37261 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37321 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37381 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37441 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37501 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37561 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37621 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37681 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37741 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37801 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37861 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37921 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37981 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    38041 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    38101 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    38161 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38221 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38281 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38341 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38401 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38461 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38521 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38581 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38641 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38701 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38761 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38821 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38881 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38941 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    39001 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    39061 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    39121 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39181 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39241 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39301 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39361 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39421 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39481 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39541 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39601 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39661 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39721 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39781 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39841 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39901 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39961 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    40021 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    40081 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    40141 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40201 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40261 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40321 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40381 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40441 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40501 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40561 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40621 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40681 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40741 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40801 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40861 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40921 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40981 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    41041 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    41101 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    41161 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41221 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41281 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41341 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41401 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41461 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41521 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41581 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41641 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41701 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41761 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41821 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41881 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41941 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    42001 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    42061 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    42121 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42181 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42241 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42301 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42361 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42421 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42481 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42541 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42601 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42661 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42721 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42781 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42841 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42901 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42961 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    43021 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    43081 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    43141 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43201 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43261 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43321 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43381 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43441 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43501 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43561 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43621 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43681 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43741 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43801 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43861 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43921 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43981 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    44041 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    44101 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    44161 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44221 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44281 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44341 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44401 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44461 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44521 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44581 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44641 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44701 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44761 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44821 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44881 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44941 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    45001 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    45061 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    45121 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45181 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45241 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45301 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45361 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45421 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45481 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45541 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45601 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45661 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45721 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45781 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45841 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45901 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45961 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    46021 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    46081 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    46141 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46201 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46261 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46321 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46381 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46441 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46501 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46561 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46621 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46681 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46741 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46801 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46861 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgc
    46921 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46981 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    47041 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    47101 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    47161 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47221 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47281 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47341 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47401 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47461 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47521 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47581 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47641 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47701 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47761 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47821 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47881 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47941 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    48001 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    48061 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    48121 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48181 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48241 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48301 gaaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48361 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48421 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48481 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48541 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48601 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48661 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48721 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48781 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48841 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48901 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48961 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    49021 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    49081 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    49141 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49201 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49261 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49321 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49381 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49441 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49501 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49561 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49621 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49681 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49741 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49801 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49861 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49921 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49981 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    50041 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    50101 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    50161 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50221 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50281 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50341 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50401 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50461 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50521 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50581 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50641 cgttgatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa
    50701 acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca
    50761 ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg
    50821 tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct
    50881 ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag
    50941 ctaactcggc agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt
    51001 gcgaaccggg tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg
    51061 tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa
    51121 agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca
    51181 ggtatccttc tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt
    51241 ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt
    51301 cgccaatcag cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat
    51361 tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat
    51421 aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta
    51481 gttcgccatt tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt
    51541 ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc
    51601 cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac
    51661 tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg
    51721 gtgtgaaaaa atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg
    51781 ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg
    51841 tcagctcttg agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat
    51901 ctagttcagt ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca
    51961 agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt
    52021 tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta
    52081 agacgatcgt actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac
    52141 ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga
    52201 tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat
    52261 tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag
    52321 ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat
    52381 aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca
    52441 tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta
    52501 tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc
    52561 tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt
    52621 ttaggtataa taaaaaatag gagaaaaagt agaaaagaag gtgtttgtta tttgggaagt
    52681 agttaaatcg agagtacaag aaatgaatga acatttctca gtgtcattcg cagaaaatcc
    52741 aagtaagtat tttcgacgtc ttgtttttct gctcatctta tcattgctgt taacagttgc
    52801 aatgttttta ttgccggaaa aaatccgaga agagcaagta aatagtctcg tttattcgtc
    52861 cataccaacc agcaaattga aaccttttga ttacagcaaa gctgatcaga aaatcaaaca
    52921 aagccgggcg atatcggtga tgttcagcaa accgaacggg aaaacctatc aggacatgct
    52981 tgatgttttt aatgatcctg agcttatgga agaattgaat cgaccgatct tttattatcc
    53041 gatcgtttat gatgtacatg aactggaaca aaaatataac atacgaacgg atgaagtgac
    53101 atttattttc tttgatggag gaaaagaagc aaatcggata actgcgggta agggaggaat
    53161 aactgatttt gataaggagt tgatccctga actgaatcga cttccgttag ccaatatcaa
    53221 acaattagaa gaagaattgg atagaacggg agtaacttcc caaaattccg agattgctaa
    53281 ttgagacatt ggcgcgatga aacggtgggt ctatatagcg ctatttttaa ttatcagaac
    53341 aagtgatgtt tgatcttcaa aataacaaat aaaaaattaa aaaatatagt tgacgaaatt
    53401 caaaaattcg atttgactta aatcaattct taaggaaagg gtgacctgta atgaacttat
    53461 caaaacgtat ttcagcagaa aacaaaaaaa attggcgcag ctggcgtaga taagttgtat
    53521 taatggtgag actttcccat agatacaact ttttagagtg catttctaaa gcttgtatct
    53581 atgctagaca tgaacattga ctgccgcata gattagaatc tatgcggttt tttgtgtaaa
    53641 gacaatgacc gctttggcca ttgtcttttt ttgtagactg gatacttgcc tgattataat
    53701 aaataaaaag attgactttg caggaggaaa aaaatgaaaa acaaacgatt aataacagtt
    53761 gtagtaatta ttttagttta tttagcaggt gcatttattt atggaaaagc ctcaggcgaa
    53821 aaagaaagta cttcgacgaa ccagacaaaa aaaacaacag ttgttggggt attgcaatac
    53881 gtgagccatc cggcattaga tgagatttat cgaggaatca aagatggtct gaaagaagaa
    53941 ggattaaaag aaggagaaaa tcttgagatc aaatttcaaa atggacaagc cgatcagagc
    54001 aagctagcca caatgagtca acagctagta caatctgatc cagatgcctt gattggaatc
    54061 gcaacacctg ccgctcaatc attagcaaac acgacttcat cgatcccagt tgtgttaggt
    54121 gctgtaacgg atcctgtggg ggctggatta gtcgcttctt tagagaaacc tggtggtaat
    54181 gtaacaggtg tttctgatca gccgcctgtt acttcacaaa tcaagcttgc ttctgatttg
    54241 ttgccaaatg caaaaaaagt cggaatcttg tatgcttctt cagaggataa ttcaaaatac
    54301 caagtagcac aagcagaaga agctgcaaaa aaagaagggt tagaatcagt aaaatatgcg
    54361 gtgccttcca ctaatgagat tgcacaaacg gttcaagtga tgagccgaca agtcgatttt
    54421 atctatgttc cattagataa taccattgcc aatgcgatgc aaacagtggt aaaagaagca
    54481 aacaaagcaa atatccccgt cattccatct gtggatacaa tggtggaaca aggtggacta
    54541 gcaacaatcg ggatcaatca atatcaatta gggcttcaaa gcggtaagat ggcggcagaa
    54601 cttgcgagtg gaaaagaaaa accggaaacg acgcctgttt atacatttga tcaaggggat
    54661 acagtgatca atcaatctca agctgatcgc ttaggaatca ttgttcccca atcgatgaag
    54721 gaaaaagcca aaatcattac agatgactcg cagcaagaaa catctaagga ggatgacaaa
    54781 tgatcgtatc agctatttca caaggcatgc tttgggcaat attaggatta gggattttca
    54841 tgacttatcg gatcttagac tttcctgata tgacgacaga agggtccttc ccattaggtg
    54901 ctgctgtctg tgtgacagct attactcatg gggtagcgcc gattgtagct acattattag
    54961 gcgtaggtgc tggcatgata gcaggactcg ttacggggtt actttataca aaaggaaaga
    55021 taccggttat tttagcaggg attttagtga tgtcaggatt gaactcagtt attttgtttg
    55081 tgatgcgaac accaaatctt tctttattga atcatccgat tctacaagac agcttccatc
    55141 gctttgggtt acctgattac tttgacacag tccttcttgg cttcatctct ttgggcatct
    55201 tgattgctgt actgctattc ttcttcaata cagatttggg tcaaggctat attgcgacag
    55261 gagacaacga aacgatggct cggtcgttag ggataaaaac cgatcgtatg aaaattttag
    55321 gtttaacttt gtcgaacggt gtcattgcat tatccggtgc gctgattgcc cagaacgacg
    55381 gatatgcaga tgtaaataaa gggattggcg taatcgtcat cggtcttgct tccatcatca
    55441 tcggtgaagt gatcttccaa gaattgacgc tagcagaaag attgattgct attgttgtcg
    55501 gcagtatcat ttatcagcta ttgattttag tagtaatcaa actagggttt gacacgactt
    55561 atctgaagtt gttctccgct atcatcttag ctatttgtct gatgatcccg caattgaaga
    55621 aagcactgaa cttaaaaacg ggttttgaga aggaggcata gtaatgactg atatattgac
    55681 aatcaaaaat ggcagaaaag tcgtaaacaa tggaatgaat gaagagaaag tactattgga
    55741 tgaaattaac cttacaatca gagaagggga cttcatcact gtccttggcg ggaatggtgc
    55801 tggaaaaagc acactgttca atacgatcgc tggtacgctt caactcagtc aaggatcgat
    55861 ctcttttaaa gatcagctga tcacaaaaga ttcagaagaa aaaagagcac gattcctttc
    55921 tcgagttttc caagacccca agatgggaac ggctcctcgg atgacagtag cagaaaattt
    55981 gctacttgca caaaaaagag gtcaaaaacg gaaattccgt ttacgtaact tgaaaaatca
    56041 aaaagaagat tttttcagac tatgtcaaga agtcggtaat ggcctagagc aacacttgga
    56101 tactccagcg ggtgaattat ctggtggtca acgccaagca ttaagcttgc tgatggcgac
    56161 gatcacagct cctgagttac tattattaga tgaacatact gcagctttag atcctaaaac
    56221 agctaaagca ttaatgcgat taacaaatca gcggatcaat gaacaaaaat tgacttgtct
    56281 catgatcacg catcgaatgg aagacgcctt gaaatacgga aatcgtctga tcgtactcca
    56341 aaaagggaaa atcgttcaag atatttctga aaaagaaaag caacatttga caatgggcga
    56401 ccttttgcag ttctttgaag aagtagtgga ttgatttcga cagaaaaatt cctttcagta
    56461 gaaggacttg aaaactcatt gacatcttcc tttgattcat cctatactta aaacaataaa
    56521 caattaaaca tatttgggtg ttttgtagga tcacgtagtc aatgatttta acaattaaat
    56581 agaatattct ttgctctgac aagtaaacga tgagaaaaga atttgctact ttgccaccta
    56641 gacgtttcgt actttttcgt atcaaacgct aagtggcttt ttttattgaa gtaagaacaa
    56701 aggaggaata agatgatttc tggacaaacc aaattagctg ggctctttgc tgatccggct
    56761 tctcacagtt tatccccatt gatgcacaat actgcttttg aagcaaacaa catcgatgcg
    56821 gtgtatttag ctttccaagt aaatccaatg aatttgaagc aagcagtcga aagtattcga
    56881 acttttgata tgttaggtgt aaatctttcg atgccgaata aaacagcggt tattccttat
    56941 ctggatgagg taagccagga agcgcaattg atcggagcag tgaatacgat cgtgcacgaa
    57001 aagggtcgtt tgattggcta taatactgat ggtgcgggct tcatgcaatc cgtgcaagaa
    57061 gctgggattt cgatcaaaaa gaaaaaaatg actctactgg gagctggagg tgcagcaaag
    57121 gcagtcactg ttcaagcagc gttagacggc gctgaggaaa tcgtagttta taaacgaaac
    57181 aaccaaacat tcgctcaagt aaaagaaaca ttcgaacaac tcagctatcg aacttcttgt
    57241 aagataaaag ttcgtgactt tgccgatacg catcaattaa gaaaagactt gaaagaaagc
    57301 tgtcttctag tcaatgcaac agatatcggg atgggaaaga aaatcaatca gtcaccgctc
    57361 ttagatataa gcatgatgca tgagaatcta gcggtttttg atttgattta tgcacctaga
    57421 gaaacacgtt tattaaaaga agcaaaaaaa gtaggagcaa aaggatacaa tggacttggc
    57481 atgttgatct accaaggagc aatcgcgttt gaattatgga caaaggaaaa gatgccgatc
    57541 catgtgattg aaaagctgtt tgattaaaaa aggataatag ataaagatct tttattctcg
    57601 cataaacggt ctcaagaaaa gtaatccttt atgtatcgaa gcatttattt cgttattttt
    57661 tattaaatta tcaaaaaatg ataggctttt gtcgattggt tatcgtatcc tttatttatc
    57721 agtaagaaac gaggaggaac cacaatgagt cggatggatc gctataagga catccataag
    57781 aaggcgaaac ctctgaagcg ggatacgggg agtatttttg ctagaagaga acgaaaacga
    57841 acgcgtatgg aaaatgagga agatgctacc cgtatttatg aaagagagca gcattcattt
    57901 gaacatttga accaatacga gcaacagata tacagagatg caccaagagc agaagaacaa
    57961 caaaaaaata aaaaattttt caatcggcaa aagaagaaca aaccgttaaa acctcgaaga
    58021 aagcgatcgt ggaaaaaaat cattctatcg attttgcttg ttttgatcct ttattcaggt
    58081 atctcatttt ttattggtaa atatgtagct gaacatgaca caagcttaga ggcagcgact
    58141 tcagaaacct ttcatgggca aaaagcgacg aatggtgcgc ataatatttt gatccttgga
    58201 agtgatacac gcggagaaga tgccgggcga gccgatacga tcatggtctt acagttggat
    58261 ggtccttccc ataagccgaa actgatttct tttatgcgtg acagcttcgt tacgatccca
    58321 ggggtaggac aaaataagat caattcagct tatgcatacg gaggagccga tctagtgcgt
    58381 caaactttag tagaaaattt tggaatcgat tgtcaatact atgcgaaagt cgatttcaaa
    58441 tcgtttgaaa aagtgatcga tgccttattc atgaacggag tgaagatcga tgcagaaaaa
    58501 gatctgaatc tggatggtgt agatattaaa aaagggggcc agaagatgga tggacatgtt
    58561 cttttgcagt acgcacgttt ccgaatggat gaacaaggag actttggccg tgtcagacgc
    58621 caacagcaag taatgaacgc tattttcagc caattgaaga atccattgaa tctgatccgt
    58681 gcaccttatg cagctggtaa agctttagga tatacatcca cagatgtcac tgcttggttc
    58741 ttgacgaaaa acctcttttc gattgcacga ggagctggtg gcattgatcg aataagtgtg
    58801 ccagtagacg gttcgtggaa ttatgggcaa agtgattatg ctggcagtat tcttgaaatt
    58861 gataatcaaa tgaatcaatc tgctattaca gattttttga ataaatgatc ataaaaaaga
    58921 tcaagaagaa gctgcgcaag gcttttgtca tgaatcaatc aaacgattca ctcgtaaaaa
    58981 acgctttctt atggtagatt taaccaagag aggagctgtt tacattggat atctatctga
    59041 acttcaaaaa tgagtcgcgt gaagccatcg ctttttatga aaaagttttt cagactgaag
    59101 catcaggtat caccacatac ggtgaaatgc ctggaataga acaaatgaac ttgccagaag
    59161 aagcaaaaaa tctaatcacg aatgcacggc tgaacattta tgatacatta gttatgtttg
    59221 cagatacgcc agaaggaatt ggtcctgaat tagttgtggg aaataatgtt tctttagtca
    59281 tccagacaag aaatgaagaa gaaacgaagc gcctatttga aagcttagct gagggtggta
    59341 agattgagat gccactggat gctgttccgt gggctcagtt gtatgggatg gtaactgatc
    59401 gatttggcat caactggcag attaaccaag agtgacagct aaagatgaat attttctgga
    59461 aacatcaagc agcaaacgga tcatcgtttg tttgcttgat gtttttgtgt ctatttcgac
    59521 tatacggtat ctttttttta ttgccagatg cgaaaatatg ttccataata gagaagtccg
    59581 caaaaaatta agtaacggag gtcagaagat gaagacggtg atactagctg aaaaaccttc
    59641 acaagcaaaa gcctatgccg aaaccttcca acagcaaaag cggcatgaag ggtattatga
    59701 aatcagcgat ccattgtttg ctggtgaagt aaccatcact tatggttttg gacatttggt
    59761 agatatggtt gctccaggag cttatgaaga gcgttgggca aaatggtctt tagaaaattt
    59821 gcctattttc ccagaaacct tccgttacga agttccaatg gacaaacgtg cacaattttc
    59881 gatcgtaaaa cgagaattgc agtcagccga taccatcatt attgcaacag atggtgatcg
    59941 agaaggtgaa gccatcgcgt ggtcgattat tcgacaagca aacgcatttt ctaaggaaaa
    60001 gaactattta cgtttatgga tcaattctct tgaaaaagaa gcaatctatg aaggttttaa
    60061 gaatctccaa cctggaaaga actattttcc aaaatataaa gaagcgcaag caaggcagaa
    60121 cgctgattgg ctgattggaa tgaatggaag tccattatat agcttgctac ttcaacgaaa
    60181 agggattgat ggcagttttt ctcttggtcg tgtacaaaca ccgacactct atatgattta
    60241 tcagctgcaa gaagaaatca aacacttcaa aaaagaaacg tactttgaag gagaaggttt
    60301 aattacgaca aacaaagggc agttttctgg aaaaatcgta ccaaaaaaag catttaaaac
    60361 ccaagaagag ttaacgaagg aaatagaaaa acttggagcg catttaggta agcaaaacgg
    60421 acggattctt gaagttacga aaaaggaaaa gaggttgcat agtccacgtt tattttcgct
    60481 atctagtttg cagacaaaga tgaatcagct aatgaaagca agtgccaaag ctacacttga
    60541 tgctgctcaa ggattgtacg aaagcaagtt tctaagctat ccaagaacgg attcctttta
    60601 cattacagaa aatgagcatc agtatctggt taaacatctg caaaattata aaaaattttt
    60661 aggaatagaa gaagtacaga caactgagat caaagcaaag aaacgatatg tcgatgcgaa
    60721 aaaagttcaa gaacatcatg caattattcc gacaaagacg attccgactc ctgcacgctt
    60781 tgcgaagctt tccaaattac agcaagcaat ctatttgcaa gttttgcgca ctactgtggc
    60841 tatgtttgct gcagattata tctacgaaga gacgaccgta atgacgggcg tacagcaatt
    60901 aaagctaaaa agcatcggaa agatcccatt acagcaaggt tggcaggaaa tcttacgcat
    60961 caagtcaaaa aagaaagaag ctcagactct tcctcctatc gtagaaaatg aagaagcaga
    61021 agtagaactg aaaagtatgg agaaagaaac acaacctcca aaaccctata ccgaaggaac
    61081 gttgatcaca gcaatgaaaa ctgcgggaaa aacgctggat aatgatgaag cgcaagaaat
    61141 tctcaaagaa gtagaaggaa tagggacaga agctacacga gccaatatca ttgaaaatct
    61201 taagcagaag cattacatcg aagtcaataa aaacgaaata actgttacgc caaaaggaat
    61261 cactctttgt aaggcagtag ccaatgaacc attactgacg agcgcagaaa tgactgcgcg
    61321 ctgggaaggg tacttgagaa aaattggtaa acaagagggg acaccatctg tttttttaga
    61381 gaatatcaaa aaattcatcc tacatttatt ggcagaagtt cctaatcaaa tcgacaaggt
    61441 agacttttca gatgagatta gcgggacacg tcagataaaa gcgatggaga agaaaaacga
    61501 tcaattagga agatgtccaa aatgtaaaaa gggaatagtc atgctttatc ctaaaatcgc
    61561 tacatgcttg aatccggaat gcgacttcaa attgtggcca acagtagcta aaaagaagct
    61621 gactaaaacg aatctcagag atttgctttc aaaaggaaag acaagtaaag ttgtcaaagg
    61681 ttttactggt aaaaaaggga aattcgatgc agttttagta ttaaaagaag atatgacaat
    61741 cggtttttct tttccatgga tcgaaaacag tggaacaaaa gcagttgatg gaaacaaaga
    61801 aacatcaaga aaaaataatg aaaacgaagt agagtaaatg aaaacaatga aatagcggaa
    61861 tatttattcc gaaaagtgag aatataaata ccaataaaac taaaaaatat cagtgaatca
    61921 agcaaaaacg ttggggtagg ctgattttat atagatagca aggagttttt ttatttgaaa
    61981 aaagtgcatt catttttaaa ttatcttatg ggagcaatca cgattgtggc tgtgtaccaa
    62041 gcatttctaa agtatcctga ttacgggacg aagttgttgt cattgacgca caatcaaaca
    62101 gcatattcac caacgttgat tttatcgact ttgactgcag gagctaaaag cgctacttat
    62161 ttttttcata aaacgacaag catgctaaag cgaaagaaac agcgaaaaca attgttggtg
    62221 gtggtagcgg ctatgatcat tatttatttt ctaccagtta ttacacaagt atttcatcaa
    62281 tattttggtt aagaatacga gagtttgtga caaaagtcat gtcacaaact tttttctttg
    62341 tcattttttc gtaagaaaaa gcaaaataaa agtatataca ttgattaaaa gtatatactt
    62401 ggatataatg tacttactat agaatgagaa tggtatagag ggtggcgaaa tatgaaaaaa
    62461 atgaaaaagt ataaaattag aaaatctggc aatagcgatg taacaactat cccaccagaa
    62521 gtaaaagaat tcatgggtgt gcagacaggt gacgcaatca gttatgtttt tcaatctgat
    62581 ggttctgtac gaatgatcaa agcacaagaa gaacctgata ttgattcatt agttgattcg
    62641 atcatgaatc aatatgaaga cgcgttaaaa gatttggttg atttatgagg tatctttcga
    62701 ctaaagaaat tatcaaaatc aacgcgaaag ttattttacg tcactcgcca ggcgaaatga
    62761 tcggtgtaaa agatgcaaat gcattagata tggccgtcaa acagccttca caagcagtat
    62821 tcaatcaaga actctatcct gaaatctatg aaaaagcggc gattttagca attaatttag
    62881 ctaaaaaaca tccttttcat aatggcaata aacgaactgc tcttgttgcc atgttgttgt
    62941 ttcttcaatt gaataattgt ccagttgctt tttctcgtca agaagctgtt gattttatca
    63001 taatgattac cactagttca ttggatttcg attcactaaa gtccaagata accagttatt
    63061 tacgacaaac cgcaataaaa tgaacgaatt aaaaacttta tttctcaatt agatcagcat
    63121 gtcattaagg aatatgctga tttttttatg tttaatcata caaaatagtt ttttcataaa
    63181 aatatggaaa atatggatta attttgaaat aattgattta aaaggaatac aaaagagtga
    63241 atagtaggaa atagtggttt agaactagtg ggctgatttt ttatatattt tagtttacat
    63301 aatatatatt atacaaagta gatttaaaaa atgataaacc tctctcgaac ggttttttat
    63361 caaaaatcgt catttttcca tcaaaatctg cttatgcaaa attataaaaa aattttgcag
    63421 tttttcttac tttttttgtc gtttaattga atgataaaaa ccagtttctt tattcagtta
    63481 atcaaatatg aacgaattag atatgaatca ttgtatttgc cgttgcggaa ggatttttta
    63541 attaaccaca gataaacatt gataacgatt cgcttattgt aatcaacaga ttaaatttca
    63601 tatgttcata tgtacggata cattttcgga ccgattaatt ttaaccattc tgtttatttg
    63661 cttacctatt agatatcaat aaaaaactgc ttaacagcta tttcagctgt taagcagttt
    63721 taggattttt agttcatatt cattgtttct tataatacag tgttcaatac ttctcttaaa
    63781 gcacttgttg atttgctgaa cattgctttt tcttcttcgt tgattgataa ttcaacaact
    63841 tcacgaacac cattttcgtc aacgattgat ggcacacctg taaagatatc tttttcgtcg
    63901 tattcaccag ttaaataagc agatacaggc aatacagctt gttcgttatt caagatagct
    63961 tttacgatac gtgcagtact cataccaata ccatagtaag ttgctttttt acgatcaatg
    64021 atctcataag cagcattacg gactttatca gcaatcacat ctaattcatc ttgggcaata
    64081 cgatggtctt tttctacaat ttcaaacact ggtttaccac cgacagttgt atgtgaccat
    64141 gcagcaactt ctgaatcacc atgttcacct aagatatagc cgtggacgct gcgtgggtca
    64201 acttttaatt tcaatgcgat ttctttacgg aaacgagttg tatccaatgt tgttccagta
    64261 ccgataacac gtgatgttgg cagaccagat tcgttccaag cgatatatgt caaaatatct
    64321 actgggtttg aagcaacaac gataataccg tcgaatcctg atcccatgat ttcttttacg
    64381 atttggcgca tgattgacgc atttgtttta actaaatcta aacgagattg accaggtttt
    64441 tggttgatac cagctgtgat aacaacgata tcagcatctt tacattcttc atagccacct
    64501 gaccatacag ccacattttc atcgccccaa gccataccat ctaaaaggtc caatgcttcc
    64561 ccttctgctt tttcttgatt cacatcgatc aatactaatt cattagagat tccttggttg
    64621 atcattgcat aagcgatact tgttccaaca aaacctgtac cgacgattac tactttacga
    64681 cttgtttttt tcatgaataa acagctcctt ttcataacta tttgttactt tcatgaaaag
    64741 tatagtcttg tttattcatt ttatcaacat gttaattata atagttgtta ttataatttt
    64801 tgatggaaac gaattcctga atacgcataa cagataaatg acaaatgttt acacctatat
    64861 cccctgataa tacaaccaaa agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa
    64921 cgatataata agacagcaat cgcacctaaa acaattttcc ttcatatgct ttagtgaaag
    64981 attttcttct taatgtttat ttctccattc attgggagta catgttgaat acttcttgaa
    65041 taatttgaat aaagaagtcg tttgtttata tccgatacga ttagcgattt cttccaacga
    65101 aaaactcgtt tcttgaatca gttccaacgc aaagtcgaat tttttcttta gaaccagttc
    65161 ttgaaaggaa gcatcaaaat acattttcaa tttattacta agatagaccg gattgtagcc
    65221 aaaatgagct gctgtttctt ttaacgtaca agaagtaaaa tgcttatcga tataatctaa
    65281 tactctaagc atctcatttt ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa
    65341 taaatgagtc aattcgatca gtaatagtga tgtatagaga tttaacgaac ggatcttatg
    65401 actgtatgta tcaaaataaa tcaacagcat attttcaatc aaatgcgtca aacgacttgt
    65461 ttttccgccg cgaaaatgaa tgaattgtgt atgttcccct ttttcttttg atgcatttat
    65521 caaaaaagaa gaaagtagat tatttgtgct tgccaaatga ttcaatatct ctgtagataa
    65581 ggtttcttct tttaataaga tgttgattaa aatatcctct tgccctgtgt attcgattct
    65641 ttgagtagct tctttatcaa tgatcaccac gtcactttct tccatctcta tcctttctcc
    65701 attaataatt tgtaaacatg taccgctata catataattg atttcaacaa aatcatgtgt
    65761 atgctcggga acttccgcat atcgacggtg tttactgata tgaatatttc cctgttgaaa
    65821 tagatcccct cggtggattt ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt
    65881 gatattcatt ccttgttcac gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa
    65941 tgtctaattc agctagttcc aattgactcc ctcctttttg taagcggttt ctttcgctta
    66001 ttagttcacg ctgtactgct attatatgca aagctatttt tggtttcata aagactttct
    66061 atggttggga catgaacttc ctgtgattcc gctattgaga gaataaccac ttcatactat
    66121 atttttgata agcgcttaca aaaatgaaag gaacatgctt atgaataaaa agatgatgaa
    66181 attttctctg ctgtcagtct ctcttatttt gacttctgct ggtgcagtca cgtctgcaat
    66241 tcccagtatg tcagctactt atgccacgcg ttctttatct gctgttgaat tattaacgac
    66301 tgctccctct tttatggtca ctatttttgt tttgattagt agttttattg ctaggaaaat
    66361 cggacaaaaa caaactgtga tcatcggatt agtgattgca tcgatttgtg gtatcctccc
    66421 cctcttctca caaagttaca gtattgtctt agcttcaaga gctggactag gtattggctt
    66481 tggattgatc aattctttgg cagtcagcat gattgctgcc ttttatcacg gagatgaacg
    66541 agcctctatg attggttttc aaagtgcatt tcaaggattt ggtgcagctt taatgacatt
    66601 tgttgcagga cagctagtac agttcggttg gcaatatacc tttttagtct acgccatcag
    66661 cttacctatt cttgtcttgt ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca
    66721 atcgcatggc acagccccaa caagacaagt aatcaaaacg aatcctaaaa tgattagtta
    66781 tggtattttt ctcttgctgg tcatcgtggt atataatgct gtatcgatta aattagccac
    66841 agtcctgacg acttattctc taggaaacga aactaatgca gcgaatatct taacaatcat
    66901 gcaattggca agtatggctg ccggagtttg ttttggctgg cttcagacaa aagcacatcg
    66961 ctatatgctt acactttctt tactactgat gggaatcggc tttgtattga ttgccactgt
    67021 gataaacctg tatgtgattg ggtttggtgc gatcctaaca ggaatttctt tttcgttatt
    67081 cattccttac ttattcaacc aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa
    67141 tacttcaatc ttattggttg gcgctaattt aggtactttc attgcaccat atggtttgct
    67201 ctttctctct tttgcttctc ttgggagtaa aacacttgct gttttcgtca atggcagtat
    67261 cttgctgttg attagcgcgc ttattagcct tctagtagta cacaggacga atagaaagac
    67321 agtgataaga gtagatgaag aaataaaaga acaattgaca acaaaataaa tttgatggag
    67381 gtcgtgtaaa atgacaaatg aaaaacataa agatagatgg ctttggtatc ctggagactt
    67441 tgagatccgc catggactgc tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc
    67501 agcgtactgg tacatggatg attgccatcg gaacgtcaag tttaagagat attactttct
    67561 tgatcaacct tccatgttta aagtgacgat ccaaggagtt gggtatgtag aaattaatgg
    67621 acaaaaacat ccatgtggaa aatggctgac ttgtccagct ggtaaagcaa aaattcgtat
    67681 ctttgtagga catacatcag ggctaccagc gatgtttatc gagggagacg aagtaaaatc
    67741 agatattggc tggacagcaa gtaattttat tgaagaatat ccagctggct ggagtccgct
    67801 ttatgtcgat atcgcaaaag atccaaatca aatctattat caaaaagaat gcgtccatcc
    67861 agtcactgaa acggagattg gcggaggaat cttattcgat tttgggcgag cagtgaatgg
    67921 ctgtgtagaa ctaatatctc tggatgacca tatcgaatct atcactctat gttatggaga
    67981 gtccgatgta gaagctatgg atatcgatta ttgctactat aagcaaatag gaatgacaag
    68041 aaaaatgaaa gctcgtaaac gcgcttttcg ctatttgttt ataccagagg tttctactgg
    68101 aatggttcaa cttcaagttt ttcatgaatt tttatctctt tcgaaacaag ctgctttttc
    68161 aagcgattct tctttactga atcagatctg gtcagtatca gaagaagcct tcaagttatg
    68221 tagtgatttg ttttttatcg acggtatcaa acgagatcgc tggatttggt ctggagatgc
    68281 gtatcaatca ttcatgatca atcaatatct tttttttgac gaggaaatca ataaacgaac
    68341 gatattagca ttaagaggac aaaatgaaat caagcagcat atgaatacta tcgttgacta
    68401 ttcgatcttg tggttgattg gtatcgaaaa ccactatatg atgacgaaag actatgaatt
    68461 tttacgcatc gtctacccta agatgcaatc attaatgaga tacttgatgg agcaaacgaa
    68521 tgaattaggg tttatttatg ggagagcaaa agattggata tttattgatt ggtctgaaat
    68581 ggataaagaa ggaacgcttg ctgcagaaca agtcttatta ctgaaagcct atcattccat
    68641 gatcacttgc ggagatatct tagctgaaac atatggagag aacgaaaatt atcatactca
    68701 tctctatcaa gaaaaatatc aactattgaa acaaaaccta tttgactact tttgggatga
    68761 agaacttggc gcttttatcg attgctatga atctgggaga agaaatgtga cgcgtcatgc
    68821 gaatattttc gctgttttat tcgattttgc taacaaagac caacagcaat cgatcttaaa
    68881 gaatgtctta ttgaatgaca ctatcacaca gattactact ccatatttca aattctatga
    68941 acaagatgct ttatgcaaac tcggacagac gaatatcgtc taccaaacga ttcttgatta
    69001 ttggggaggg atgttatctc atgatgcggt aactttctgg gaagaatacg accctactca
    69061 aacaggaaat gaaaagtaca gtatgtatgg agatccttat ggaaaaagct tatgccatgc
    69121 atggggagca agcccaatct atcttttagg acgctatttt atcggtttgt atccaacaaa
    69181 gccaggttat gaagaattta tgatacaacc taatctagat tcatttgaaa cactgaattg
    69241 tacgctacct atcaaagatg gaaagatttc gcttgaaaaa acaaaagata agatcgtgat
    69301 tacttctgat agaacaggcg gaacagtgaa aatgaatggt aaaagttatc ctcttctagc
    69361 aaaacagcca cttgtcttaa caagctattc aaaaataaat gcataaaaca aaaaactgct
    69421 tgcgacatat cagaagactt taaatcttct tctgatattg tccaagcaat ttttattttg
    69481 aagtttgctt aattctgttc tttagaaaca atgtttgttc tttttccggc aaaaagaaag
    69541 ctagataata cgacaagtaa aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg
    69601 tattctccta gtttcccaag tacaagtcct ggtactagat aatcagtatc ggcaaatgta
    69661 gaagaagcga ttttaagatc tcctaatact ggaaggataa ataatggcag ccaactaatc
    69721 aataagctat tgaaagcaga acctaatacc gcccctcttc taccgccagt cgagttgccg
    69781 aagacaccag aagcagctcc gcagaagaaa tgtcctacta ccccaggaat gataactgta
    69841 gtttgcaagc ctatcatagc aaacatggat agtgttccta caaagaagct aacaaaaaag
    69901 ccaattaata cagcattagg tgcatatgga aaaacgatag gaacatctaa tgctggttta
    69961 gaatcgggta cgagtttttt agcaatccct tggaatgctg gaacgatttc tgccaacacc
    70021 attcgaaccc cttgaaggac gataacaaac ccagctgtga atgttccagc ttggatcagt
    70081 gcaaagatta cagcgttgtc tccattgctt agttctcttt caacaaatcc aggaccagct
    70141 aacaaagcaa gtgcgacata tacgatcgac atcaagagca tgatcgatac agtagaatct
    70201 cgcaaaaagc tgaaactttt aggaatcttt atgtcctctg tagaacggtc tttgtttcca
    70261 aaaaactttc cgatccatcc actagaagca taaccgatat ttccggtatg ccctaacgca
    70321 acttgattgt ttccagtgat gttcttcata aacggttgac aaagagcagg cgtaatagtt
    70381 aatagtgttc cttcgaagac cccgcctaat aagatcatcc acaaatttgc agtaaacccc
    70441 gcgcttacta aaatgactgc tgttagacaa gaaacataaa gcattgcttg acctgtaaga
    70501 aaaatgaatt tatatcttgt gaatctagca agtaaaatat tcacgatcat ccctactagc
    70561 atgatcaaag cagtaggtgt accgtattgt tgcaaagcaa tcgccactac tgcttcattg
    70621 ctaggaacta ctccttgagt atgcagagct gtttggaaca tcgaagcaaa aggggttagt
    70681 gaattactga ttaaaccagc accgccgatc agtactagga atccgacaaa tgttttgata
    70741 gttccttgga tcacttctga aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc
    70801 aaagaaacga ggatggaggg ctgactgacg attgacacaa acaaattcaa caatttatcc
    70861 attgatagtt cctcccttga atcattttta ttcttttgac aagatcttcg ttactttttc
    70921 ttttacttct tcgctgtcaa tgatcgattg caaaggtacg agcttttcat caggtataga
    70981 agttagcgta tctttcaaag aatgctcaat gaagaaataa tcagccatat cgctagatac
    71041 acttccaaca tccgtatgac ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag
    71101 tgcttgtttg atgttcatct ctaccataaa acttgttcct aatccacttt gacatactgc
    71161 aaaaattttc atatcattcg tctccttttc ttatgatcgc taatatttct tcttttgttg
    71221 atgcgtgtaa taaatcttga agattttgtt tattagaaag tagctttgtt aaatttgcca
    71281 aagcccgaag atgtgcctca ttatcgatag cagctaaaca gatgaacaaa ctaatgggat
    71341 gggctggatt atcaagcaga tccacaggtt gttgaagttt cagcaaagac atccctactt
    71401 cgtttacgcc atcttctgga cgagcatgag gtaatgcgat gtgatcgcca atatggataa
    71461 acgcaccata ctgctccacg cgctcgatca tagctttgat ataactttct tctattttat
    71521 tttctgataa tagcggctgt gcggcaaatg tgattgcttc ttgccagttt tttggttgat
    71581 ccgataattg gatcatttct tctgttaata attcagatag cataggacgt tgatcctcct
    71641 tcttttctaa aagtttgttc attttacgat ttaatacttg atagagcttt tcttcgtcta
    71701 cgccttcttt taattcgata taaggcagta gcgccgacaa caattcttgg gcagaaggca
    71761 ttgaaaatcc tggtatcagc caatctcttt gtacttgatt gatcagctga tttttttcca
    71821 agtcagtcat gattggatgc agaacataga gagacttttt cttatcagta agtgtgagag
    71881 gtacagtaga aaaaataata tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg
    71941 aattagtctc tgtaaaaaag atcatcggga ataattgctg aagttcactt tttaagatca
    72001 atgaagagct aatgccactt ggacagacga tcacggctct tatttttcta tttctttctt
    72061 ctgcgtccgc ttttctgatc tctccgccaa atagtatagt gaaaaaacca atctcttctt
    72121 cagggatgct cttccctatt cgtctttcta acggaagtaa tgcttttctt gtcatttcgt
    72181 agatggaagc atattgatgc ttaatttgat cgatcatcac attaggtaaa taaaaagaat
    72241 aggaaatacg aaaataggca gggaccaagt gataaaagac attcatcaat aattcacgaa
    72301 acgaagcaaa ttctacggcc atcaggaatt ccatgcgatg gatgacttct gaagaacatt
    72361 ccagcaaaaa atcaagtgca ggctcctgga catctccttc aacgatcgat gctaagcaaa
    72421 gagagaaaaa tataatctcc gaattttgat gttcggaata gccaaggcca gtcaatactt
    72481 gtcgactaat gtcagtgact gcaagagaag ccaacagttc agcatctttt accagttcca
    72541 tggatgtttt tccaattcga atggttgtca aactcaaata ataagctaat tcatccattc
    72601 gatttggtgc gaatcgaaga tctgatagtg aaatcgtttt atctagcaaa tctctaactt
    72661 tggcgtaata atcaatggaa agggttgcgg ttaaatacgt gagcccaaat cttccagcaa
    72721 gtgactgcat caaacgagca gtgcgatttt ttgctcctct tcttaatatt gcttctgacc
    72781 ctagcagcct aaaaccagtt ttcctagtat acgacagctg acaatcttcc acttctaatt
    72841 catttcttat ctttttgata tctgacagga ctgtcccttt agaaacctga agaaaatctt
    72901 gaaaatgaaa aacagaaaca gacgttgcag tcgaataaac catcaaataa agaagatctc
    72961 ttcgctcttg ttcggtatac acagcttcaa atcgagtaat atccaaaaat ttttctgccc
    73021 agtcgattgc tcggaatttc tttatacgga tacgggtatc atccacatat tcggcaaaag
    73081 gagttaattg tttgatcgcc tcgcttgtat ttacttcgat gatctctgct gctttttcta
    73141 gactgatttc tcttggtgtt ttcaggagat aactaatttt gtagttcaca gcgctgttca
    73201 cctcctactt atattctagt atggtagcgc ttttaaatcg aggggtgttt ggtacaactt
    73261 acagttggat tttttttacg actgtaccga acgatttcta tcgaatggat acagaaaaaa
    73321 agcaggtgac caaatgtctc ctgcttttat gaattgattt cgtccgatca atgatgatca
    73381 tgtttatttt ttgaggtcag ttcttcaaat ttttctttga catcttcaac cgctttttcg
    73441 atatcttttt caaagtgatt gggctcatta ggctttgttt cctcttctac agaatttgaa
    73501 ccagataaag ctgtttcttt attttctgtt tcaccagagt ttgtgccagc taatgattct
    73561 tctttgtctt ctgtttcacc agaattagtt cctgctaaag ccacttcttc ttctgtttta
    73621 ggggccattg aacctcttaa tcgtttgtgt ttttcaccgt cataatttgt catgttggtt
    73681 cctcctagta gttctatact ttttcatcgt acaataagac agtttatgcg tcaaaaaaca
    73741 aacccgattc ttacaaatat gtcatatttt tccttctgat tcttgaatgc ttttgattcc
    73801 ttcttccaaa attttcattt gtaagattgt ttcttcatct ttgatgactt tttctgcgcc
    73861 attaactaat gtctcgtaaa tcccttcgta gacacggctg taatcaccaa cctcggaaat
    73921 tactttttct tcatgataac tcccttgttc atctatatag gtcaatacac cataatgttc
    73981 gggcaaatcg ataccaaagt cttcatgatc aggcatgtaa aacattttca gatgttcttc
    74041 ttgtcgatct tttgtttgtt tcacgaacat cccttttttt ccgtaaacga cgaaacttgg
    74101 acgttctttg atgcggaaat aactggattt tatcgaaatt ttcatatttc catagaaaaa
    74161 atccagatcg aagtaatcat tcattcgtcc tttccctaaa agttgacgta catcatagct
    74221 gatatcatct ggttcgccga aataagaaag aacttgatct actgtatgac aagcatgtcc
    74281 atataaatag ctgttcgcag tagaaaattc atgcgtattt tctggtactt ccggtctgaa
    74341 ataatcataa tgcatttcta cttctaaaat atcccctaat tttccgcttt cgattacttt
    74401 ttggactgtc aagaagtcag aatcgaaccg tctgttttgg taacattgga taaatagacc
    74461 tttttctttt gctaatgcaa ataactcttc tgcttccttt gacgtttctg caaaaggttt
    74521 ctctactagt acattcttac catgttcgag tgccattttt ccatattcat aatgaaattg
    74581 actaggtgta gtgatgacaa ctaattggat ctcaggatca tcccaaagat cagacagctg
    74641 atcagtatat tcgatgtctt cgaatgtttt ccacactggt tcagatgggg aaaaaatttt
    74701 tttgatattg attttgttcg taagttttct tgaaaaaggc aaatgatagc gatttgtact
    74761 ctttccattg ccaagataag cgattgtaag catgagtggt gcctcctttt attgatgttt
    74821 tcagtatatc ctagaaaagc gcagaaagta tttataatag ctattctggt aaaaaagttc
    74881 agaaaaacac ttgttatcat tcggtttggt gaaattaatg ttcaaagtaa ggataaaaat
    74941 caaaaagata gtagcggaac caagtgttta tcagtaagat agaatttgga ggtcagatca
    75001 tgcttattga agaaaaacta acaaaacaag agttgtttac cacgacagag aaacggattg
    75061 tcgattacat ccgtaggaat atcgaagctg cagtctacat gacgattgaa gaattagcaa
    75121 aagctacgta tacttcccat tcagctatca ttcgtttatg caaaaaaatg ggattcagcg
    75181 gatttaaaga attccgtttc gagctggggc gggaagttca tcaattgatt gctcagttca
    75241 atcaaacgat tgatcctaat tttccttttt caagtgaaga tagcactcag caaattgcaa
    75301 agaaaatggc ggatttatcg atccagtcaa taaaaaaagc acaattgcag attgaacatg
    75361 aagatttaga tcaaatcggt aaagtattga acaaggcaca gcgaatcttt ctttttgcaa
    75421 aaggtgattc tcaaatcacg gcaaggaaat tccagaataa aatggtcaag ttgaataagt
    75481 ttttgatcat ggctgaagaa tacagtgatt cttcttggaa tgcagccaat ttgactagcg
    75541 aggattgcgc catttttatt agctacagcg gtcgcatcca tcattatgaa cgaataatga
    75601 cctatttgaa gcatgtagag gcccctacct tgctgattac cggaaatcag cattcagaaa
    75661 tggccaaaca ggctgatatg tgtcttgtta tatcgcagga ggaatatgat tttgctaaag
    75721 tagcgacttt ctcctctcaa attgccttcg attacgtatt aaatacgtta ttctcagtga
    75781 tatattctca aaattttgaa gagaatatcc gcaacttgaa aaacaaacaa gaattgatgc
    75841 aaaaaggcct tcttaaagaa tatcggaaaa cttaagaaaa gatcctcatt tagtaataag
    75901 aaagatagtg tttgataggc tctctttgat atcatcataa aaacaggctg aagttttctt
    75961 tttcaaacct cagcctgttt gtttacggaa cgattcgaat agatatatta tagaaatgag
    76021 gaatagctaa cttctgtttc ttattttgaa cgattgacga aaaagatata taagaaggag
    76081 gaaaatcagt atacatgcag ctaacaatcc atacaggaaa aatcgtttgt tctcggatac
    76141 tttctgtact tctttttgaa cttcttttgc atgataagga acccggtgcc ctctgacaag
    76201 taagcgatga ctgttgacca tataaggtgt acaagttagg agtgtcacga aatcctgccc
    76261 tttttcgatt ctcagatctt ttgtatcagt cggttctacc gtcttgatct gatcgacttg
    76321 ataagcgagt gtccgtccat tgatttcgat atagaaagaa tcacctaaag tcagtttcgg
    76381 taagtctgtg aacaactttg cttgaggcag tcctcgatgg ctggaaataa cggcatgtgt
    76441 attttctccc cccgtaggat aagacgttcc ttccaataat gaggcacctt tttctagcag
    76501 cacagtattc gtttcatcaa aaattggcaa atggacattg atctcaggga tcgtcaaaat
    76561 accgatcgta tgtttctcaa aataggttct atcctttttc gcaggttctt ttttcttagt
    76621 aaagggatct gcacctggat ttccaccttc ttttgctaat tgctggtttt tctttgtcat
    76681 gttttcttgg attttagcca tgacttcttc attttctttg accgcttgtt gctgataatg
    76741 agagatgatc tgctgatcca gataattatt cagcgcgtcg ctaacaaatg gataagctag
    76801 tatccctatt cctgagagaa gcaagaaaag catcagcaga tctagaagtt tccttttctt
    76861 tggtttcatt tgtgttctcc ttgtgatgac tgtttgataa taaaagaaaa aggagcattt
    76921 gcgtaatccg ctgctccttt ttccaattct tgcaaaaaga ctaaatctga ctgtgcttgc
    76981 gtctagcaaa gtacagtcca gcaatcagta gaaggactac tcctgcaccg atatacacat
    77041 agattccctt accgcctgtt gaaggaagtg tacctttgtg tttatttggt attttttcag
    77101 gagaaatcaa ctgtcctgct gttacataag attgttcatc gatagtaaat gctacacggt
    77161 ttgttaatgg aacatatttt tctggcgctt tcgtttcttc cagatagtac gtgccatatt
    77221 ttagacctgt cacatcgatt aaaccgttac ttgtggttgt aaaaaccgtt gctgattctt
    77281 tcgccgatac ccagctgacg gcttttgtgg atgggtcgat cgataaatat ttcgctgtgt
    77341 cactatcttg atcacgaacg acgaattctg ctccagcaag tgtttggtct gatgtaacgt
    77401 caccatctac tttaacaaat cgtttgcccc cagtaacgac atcgactgac ggtggtgttt
    77461 gatcatttgt atgcccgtta tcgacatttg cttggttaga aaatcctttg gttggatctg
    77521 ctttttcgtt caaatgcata tagtaaacga atttcaatgt accgccagga gttaatgaag
    77581 gaatataatt cggatcaact gaaaccgtga atccgtctgt ttgctcagtg acagaataat
    77641 ttactgggtc gatttcttta tttccatcat ataaggcata agcatacgtt cctgaagaat
    77701 cattatcaaa tgttaaagca gcgtcatgag tatcgataag tttgaatgtt gtgtacttgt
    77761 tttgcgttcc ttctttatca gcgataccta atgggatatt gacagaaatc tcatattgaa
    77821 ttttttcacc gattgcgaca tcttttccat tcaattgagg tgttgtttta tcaactttag
    77881 acgtatcatt tttgatggtc ttttctactg gtgtttggct atttgccagg atctcaaaag
    77941 gcgtgattgt ttgcttttca atcatttccg cattatcagg agcttttact tcttctaaat
    78001 tatattttcc aacttctaaa tgattaacga tcaactggcc tttttcaata gatgcctcgg
    78061 caaagtcatt gttgccgatg tcataagaat gaccagtaat gaaatgtttg gctttggttt
    78121 gatcagttgt ccaagtgtac aatccatctg tgacactttg gatgtatttt ttgacgcttg
    78181 gtgttccttc ttctttagaa ataataaatt ctgctccatt tagtgcttcg ttttcggcag
    78241 taccgatttt tgtaactttc aacgttccat cattaccgac tgtattttta gggtagagat
    78301 ggatagtatc tagttcttct gtcccgtatt tataagagcc atctgcttgt ttgatcatct
    78361 catatacagg gaaagctaaa accatgtttg cggcagctga cactccgtct tttggttctt
    78421 ctttgatcgt gtagactgca tctttcccat tttgtttttt aggtaaagat aaagtgacat
    78481 ttccatcagc atctgtcgtt cctgaagcaa ctggtgtacc aggagtcaaa gactggactg
    78541 cttgttttgc tgcatccacg gacgctcctt tatctcgttg cgcataaaat tcttgagtga
    78601 cgttataaac tgaaaatgaa atatcggcta atccttggta ttgatcgaat tcgctcattt
    78661 ctttcccgct gttttggatt aaaggatcgg gtaaatcagt cattttcttt ttatgaagga
    78721 tgacttgagc tgctgtctcc tctgcaaaca ctttttttgc gccgaagctg tttgtgagta
    78781 atggtaaaat aaggaaaagg actcctaaca taacgtttat ttttttatga tttttcattt
    78841 tttcactcct gttctttttt tgataaacaa ccagattgca aagcttgcga ataccatacc
    78901 aacaacgcct aaaagtgtat ttttcgtttc gtttgttttt ggaagaaatg gacggctatt
    78961 ttctttttta ttgactactt tcaatatact gtccgcctct ttatcctcag aaagaaaagt
    79021 tgaaatggta aacggaattt ctgtttcact taaaatataa ccagaaggtg cttcgatctc
    79081 ttttaatcga taacttcctg ttttcaaccc ggaaattgaa aaagcgccat ttttatcgga
    79141 aatcaggtga agcgcatctg attcgttctt tgtccacttg tatccgttgg ctgtttgctg
    79201 gaggtaattt cctgctttgt ttttaataag gaatactgcg ccagctaatc gtttatctgg
    79261 tttatttgtc tcgattttga caaattgctt actccctgta tatacagaga ctttctttgt
    79321 actgacacca aaaccaaaat ccagtgttcc gttgttgttg atttccttgt tcgcctgtgc
    79381 tgtactgctt agctgcatct gataagaaat ggtcagtttt tttccagcat atttttccaa
    79441 cgaagggatc gaaaataaaa catcaaatcc gtgaggtttc ttgtgtatga caaagccttc
    79501 tgtcagcttt tctccattcg atgaaatcgt taaactatta ggtaaaaacg ttaatgcttc
    79561 atccgcacta tctgacaatt cgaacttttg atagtcaagg atatttacag gaattgtcgt
    79621 atgcaaggaa taagtgattt tttcaccaat cgtaaaatca tttctaggct cttctaatac
    79681 cttctcaaaa ggtggatcag ggtagtcgtt ttcttcattt ttaggataca aatggatagt
    79741 tgaaagtttt tgattgtttt gtccatgtac aggaagaaca actaccatat tctctgcctt
    79801 ttctttgacg acttctggta ctttggattc aatgaaaaga tacgctttat ctcttttttc
    79861 ttgatcttta gcggccagag aaaaagaagc gataccatct tcgttgttaa gagttgtagt
    79921 tgttgcttct gcggtaaaca taccggaaga cgcaccgttt tttgcgatct ctgcttgtgc
    79981 ttcttctacc gttttgccct tttcccgtag atggtaaaaa gaatctgtga catcataaac
    80041 ttggaatgtg acaccattta atcctcgata cgtttgtaat aaagcttttt cttgtccgtc
    80101 atttggatga tttttcggca gttgcccgtt tgggaaaagc aatttgtgta aagtaatctg
    80161 aaccatttct gtttctgttt ctgttgctac ctgagtaaaa gctggtttaa atagtaacaa
    80221 gaagagacac atactaagcc aaccaagttt tttcatattt agctgccccc tctttctttt
    80281 ttcaaaaaaa gataccaaat agaaaacgca caaccaatca tccctactag atagattcct
    80341 aaacggccaa ttcctcccgt ttcaggtaat ggtacttttg cctgattcgt gatgtctaaa
    80401 gaaatctggt tgtttttggc tcctggtgac agaacagatt catgatcttg tccatccact
    80461 tgaattgacc catcttcgtg tataactata gtaactggct cttttagacc ttggtatcct
    80521 tctggtgtaa aagtttcggt cagcgtataa gttccaggtt ttaaattttc gaatagaaag
    80581 gtatctgttt cttgtccatc ttttggcgat tctaagtcca tttctggtcc ctgcagtctg
    80641 aattttgctc cttttaatgt ctgtccgttg tcttcttttt tgtgtaccgt tagatcaaac
    80701 gcttttagtc gattttgatg agtgagcgtc catacattat ttgtcatctc ggtatttttt
    80761 cccgtgtaaa tgatttttcc atatttatcg atttggaatt cataatttcc cggcgaagta
    80821 tcatatccgg caggaccagc tgtttcaacg actcgatatt taccaggtgt gagtgaatca
    80881 aaactggcaa gacctttttc attcgttgtt tggctgtcaa ttggctgata agtaccattt
    80941 gcttcttttt tctgtaggga aaatgctgct cctttaagat ttatctcttt gtccgtccct
    81001 tgcatcgcat acttacgtac tgctacagga acttcaacaa aaggattttc aatagtcaac
    81061 tggatcgtat catcggaagt agtgactgtt tttccatcaa tggttaccgt accatcagaa
    81121 gcgatcttga tttcccaagt agtctttttg cttaatccat gcccttctgg agcttttgtt
    81181 tctgtcagcg tataggtcat ttctttttgc aatttgacat tttctggaag agaataggtt
    81241 ccgtcgccat gatctgttag taaagtatca atagaatctc ctgttaattt gaaaacagcg
    81301 ccaataagat ccttttcacc tgtagaggaa tttttcgtta ttttcaagtt taacggtgtg
    81361 aattgtttag tatttttcca tgtcattgca tctatttgtt gagaatcgta tcctggtaca
    81421 ggtaattctt tgattgtttg gtaactgaat gcttgacctt gattattgta ttgaggtagt
    81481 gataatatct cttgataact ttctccgcta tttgcagata atttgtcaat gtctgcacgt
    81541 tcccacgtat ttgttgtatc tttagctggt ttaatgattc gaatatatcc gtttttccaa
    81601 gctgcagcat ttgtcgtatg ttcccgttga atctcaaaag taacttgatc tggacgatca
    81661 gctagattgt tgtcaaattc ttcccataac tttttgatgt gaagactgac tccgggagct
    81721 ttagcagatg gtataccgaa ttcagctaat tcattggtat caatgtttgg ctggaaagtt
    81781 gtcctgccgt tcatttgata ccagaaattt ggatggaagt cctcattttc tgtttggatt
    81841 ctcacttggt aatggatttg gatttcttgg tcttttccta aatagatctg attgctcttg
    81901 atggtatttc cttctatgga aatagatgga gtgaccgttg taggacttgt ccccacactc
    81961 ttgactgaaa gtgtaccagg ctgataaatg aatggttctg cgattggatc atttatttgt
    82021 ccattgctta cagttgctga gatctgtaca gcttttttgg ctaggtattc agagatatct
    82081 gttgcatgat cagctgattc atagtaaaga tcgccttttt catctgatga aaccatttgt
    82141 cgcatacgag actctacttc tgcttttgag agaccagctg ccggatcgct ttgaagttgg
    82201 atgccaagac catgtatttc gattcctcgt tctttgagtg ccatcgcttc tccgatggtt
    82261 gcgataaacg tactgtcgat tcttctggat agattgtttt ggtcaggtgc atcatagatt
    82321 cttgagatta gagaagtatt tcccggccga tcttgcgtat tagaaaactg agttccgtaa
    82381 taattgctgc ttgattgtgc gtgtacccgc tgtactttat aggaaaatgt tggtacacca
    82441 tccgtcagca aaacgatcac ttttttatgt ccatttggaa cggatagcat gcttcctgca
    82501 tctcttagtg ctttttgtgt aaaagtacca ccatttgtcc gtgaaggtgt aatggatttt
    82561 acttgatttt tcactgaatc aaatgaaccc atctgtactg caccgttact gtagctatat
    82621 ccttcgcttg agtagccgac atatcccata ttgattttgt ctgtgatacc gctatctgct
    82681 aaagtatcga caaaacgatc gacaccaatc tttacttcac cgatccgatt attgtcgttc
    82741 atacttcctg accagtctac gaccaatacg agatcaagag gcgtgatatc tttttgtaca
    82801 tttccacgag cattcaaata aacatcaaac aatccgggtg tacttgtttc ctttgcatac
    82861 tttcgtatcg catagtctgc ttgattaccg gttcctccat attcgatata cgaatgggtc
    82921 cgatcattag gatctccatt ccaagaattt ataccatccc attgatttgt tccgttttta
    82981 ttgccttgat gatcaagaac atttgtattt cctgtaggtt gccaactggc tttaggataa
    83041 gtgccctgat catctgttgt atattctgta ggaatcgttt gattagatgg cacactcaca
    83101 gctggcaagg ataatgtagg caatgtaaat gggctgacag aattttcgtt ttcttttgat
    83161 gattcttctt ctatttcgtc tggctttggt actgacacat ctgtatcttt cttattttct
    83221 gtctcatcaa taatgtcata ttctttatta tcgacgatca gcttgtttgc ctggctgtgg
    83281 taaagtgctg gatcgattgg aaaactcaga tcgatagttt gtttagtgtt tgatgagatt
    83341 tccaacgtaa ttttcccgct atttacctga taagcatagc catctccttc ttttctttcc
    83401 acatcactta agtaattttc gactagacca atttcttttt ctatcttttc agcactggtg
    83461 ttattcgcat ttagcttgat gttcagtgct ttttttccag actgatccga aatgacttca
    83521 gctgaaattg tttctaaaac tgttggatca tctgtagtgt ctgctattgc agataatggc
    83581 acaaagtttg ataaactcaa tattatcagc atgaaaataa ctttcagttt cttccctgtg
    83641 gtcgtcattt ttcccctcct ttttcttttt ttctgttttg acgtgaatag tgaaaattat
    83701 taaaataaac aggcgttaca taattttatt tattttaata tgataattat tatacgaagg
    83761 gcgctaaagg gaatcacacc aattttcata ccaattggtt tcatttatga agttgattcc
    83821 ttcgattaat gagcgtttca ttgaaagaaa agggttgagg gagaaaaaca tatgatcagg
    83881 ttgttggaac gaaactatag aaagatggaa aaaatcattc gaattctgtc catttctgac
    83941 aagtggatga ctaaaaaaga acttgccaaa cgaattggta gttcagaatc tacatttgta
    84001 aggtatatcg aagagatcaa aatccgctgg ggaacggatg taacgattca atcttcacaa
    84061 aaattggggt atcgtcttga acatttgaat gtaccagctt atttaaatgt tctgatggaa
    84121 atgtcgcaaa gttctacaaa cagtcgttta ttaaatgaga ttattgtcaa tccgggtaaa
    84181 acgattgagt attattgtga aaaaatttcc atcagccggt cttcttttac acgtaagttg
    84241 aaacaatgca atcaaatttt agaaagctat ttattaaaag tgatcgttga ccaaggtttt
    84301 cagttaacta gccttaaaag tgagctccag ttgcgtatct ttgttacctt tttcttttta
    84361 agttactacg gaagacgcac gttgccattt ccaatcgaaa aaaagaagat caaagaaatt
    84421 atggtcaaga ataattgtca gatgaatttg tttcaggaag aaagcccata tgagcaatct
    84481 ttctttatta tgtattttgt tgtgcatctc atgagagaat cccaaggaac tccatttgaa
    84541 tggaaagctg gagactctta tgtacagttg ataaatatcg ataaaaaaga cttcttaatc
    84601 ttgaaaaatc tcttaggaaa attgaagtac agcagctata taaaagtagt gaactatttt
    84661 gtcaatacga ttttttcaga attttcggag aaagaaaaaa atgaaatcag tgagcagata
    84721 cgaaaaatat gtcctactgt tcgttttcat ccgctgattg caaagaaaaa aacgaagaat
    84781 atgttgttca attattaacg caaatttatt ttttctcccg tattttccca tacgatacga
    84841 ctcatttgac gatccgtgca acttactttg cacagcagat gcaacaccgc cagatacgtc
    84901 tatatgctgg atttcgtgca gaacttcaat tttattccac tctactgaat cagaatctga
    84961 tttattattt atctagctat atcttttgga tgcttatcgg taatcctgaa attcaccatt
    85021 atacttctga taaaaaaata ctgattatca gcgacttaag tcttcgacat agtcaatata
    85081 ttgaagaata tatcagtgat attcttgctg tgcataaaat tcactctgag acaactgcta
    85141 ttactgaaga tcagctgtcg aaatacaatc ttctcgagta tgatctgatc gttacgaatc
    85201 aacccatttt gaatgcccat gttcctcata tattgattga tgatagtgtg tcattcgcaa
    85261 atgaagaaga actcatccgc ttattcgagt tatgaataat caaaaaacag ctatgtataa
    85321 accaccctga taaaaatttc aggacaaata cacatagctg tttcttttta ttgtattcct
    85381 tcagcaatcc aacgagattt atagcgaaag tcttttaaca actcttcttt tgtccaatta
    85441 tttgcaatga gatccgtcaa agtgttcatt acgagggtca tggaaaagta taggaaacta
    85501 actgcttctt ccgacgattg aatggagaaa tgattgattc ttaataattc cagccatttt
    85561 tcgttcattg gagaatcagc cgatagttct ctacgtttgg ttgtctgctg atcatttcgc
    85621 tgggttaaca agtataacct ttgccaatag atactttcgt gatctaagtc gcagcaccac
    85681 tctaaatatt tttcgatccc caaaaagaaa tgttgtttgt tttcgctaat gaattttaag
    85741 atatcttgat ggactatgtg agaactgctt ttgatcgtat acaaataagc atcttccaaa
    85801 tcttgaaaat atttataaaa agcaccgcgc gacatcccca tcttgtcaac gatttctgag
    85861 actttgactt ggctgatgtg ctgtgagcaa aatatctcca gtaataggtc atcgattctc
    85921 tgtttctttg cgttcgataa attgaaaaaa gtttcttttg gcatccacat ctctccttta
    85981 tctctgatta tacgtggata gcccttcatt gtcatgaagg attcattcct tctttttctc
    86041 ttcttctgtc aagtacccat cttccattcg ataaacgcga tcactccatt gaatcatacg
    86101 gacatcatga gtaaccataa tagtcgcttt ttgtttctca tgagcttctt taactagtaa
    86161 tttgacgact tcatatgcat gatctgtatc caaactagct gttggttcgt ctgctaagat
    86221 caagcttggc tcattatata aagcgcgagc aattgccact ctctgtcttt ctccaccaga
    86281 aaggtcttta ggataactat ttttaagtga ctggatatct aaagattgca gcaaggaatc
    86341 gatttttgtt gaatcttctt tttttgaagt aacttggtca actagttcaa attgttcctt
    86401 taccgttaaa aaaggaatca aattagagct ttggagaata aatcctattt ctttaaagcg
    86461 taaatctgct cgtttttttt ctggaagctc agttagtgag tgaccgttga tcactatttc
    86521 tccggaagtc ggtgtttgca atcctcctga aatggtaagg aaagtacttt tacctgaacc
    86581 agaaggacca atgatgctga cgaattctcc ttcctttaca taaaaatcaa ttgctttcaa
    86641 agctgagacc tttgtatgac cagaaccaaa tgttttggta acttttttca tcgttaatat
    86701 ttttttcatt tttattaacc tcctattgct gtaattgggt ctactttggt tatcgtacgt
    86761 atcgaaaaca atccgcctag cattgcgaca atgatcaaaa tcccactata tagcaaccat
    86821 tgtgaccaaa aaacagcaaa aggcatcgcg cttggtaaaa tcagactagt caaataagca
    86881 aacaaaagag caagcagaac gcctaccacc ccaacaataa aggactgtgc tactaaagat
    86941 ttagcgatga agaaattttt gatcccttgt gctttcatta ctccaaaaat agcagtcttc
    87001 tgaagtgtca tcacgtacat gaaaataccg accacggcag caaccactaa gaacaaaaag
    87061 tatatcatcg catttaaggt catattttgg gcagaatagc caggaatact ttcaatgaat
    87121 gtcccaatag ttaataactg tagacccttc gatgcttttt ctttcgaaat tttagctgaa
    87181 tcctttatta cgatcccatt gatcggctgt tcttcttcag aagcaaacgg ctgttgtcca
    87241 tacttcaaag cagtccacgt atctagggac gcatagatga cgggagaaac tgtgtaataa
    87301 gtttcaggaa agataccgac aatcgtcaaa ggatcgtcgt aactgccaat tttgatcgta
    87361 tctccaattt tatagcctga atcagccaga ttttgagaga tgatgatttc attctttgtt
    87421 ttaaattcat gccctttcgt gagttttggt aataaaaatg cttctttcgt tgtgccgaaa
    87481 actgtaacat tttctttgtt ttttcctttg attgctccgc tgtacaatcc gattggtgct
    87541 ttctctcctc cttcaatgta tttcagatct cctcttgtta attgtgaagc tgcaaatact
    87601 tgatttgcat cctccgacaa aacaatctct tgtgcgtccc aatcatcgat tgctttttta
    87661 aactcttctg aaagtccatt cgctagtcct gacaacatga atacgacata cgcaatcaag
    87721 aacataatac cgacgatcaa gccatatcgt aatttagaat agcgaatttc tttgatagct
    87781 agaaacattt gtttttcctc cctatgatag attgatagtg acaaaatgtc acttgttgaa
    87841 tagtgtaact ctaaagtgac aatttgtcac ttgtgttgtt tttttcttat caataaattg
    87901 tctaagacat ctttcgataa aaccttaaca tgagtcataa aaaatttatt taagccttat
    87961 ttatgctttc catgataaac taaagtgacc aaatcaatga ggtgggaaaa tgattaaact
    88021 attagtagta gaagacgata aagtattatc caataatata aaagaaatac tcgctgcaat
    88081 cggcgagata acacaagttt atgatggtag tgaaggactg ttcgagttgg aaagtggagt
    88141 ttatgatctt gcaatcttgg atttgatgat gccggaaatg aatggatatg aagtgttagc
    88201 aaaaatacgg aaagaaaaaa tacagactcc agtattgatt ttgactgcaa aagatagttt
    88261 ggaagataag attgaaggat ttgaacgagg tgcagatgat tatctaacaa aacctttcta
    88321 tcgagaagaa ctgatcatgc gcgtgaaagc attattgaaa cgctcgctag gtctctttga
    88381 tgaaaatgtt ctgaagtata aggatatcag ttgtgattta aaaagcaatg aagtcttgta
    88441 taaagaacaa gttttgccca tacaaggaaa agagtttgaa ttgctcgttt attttttaca
    88501 aaataaggga atcattttga caaaagagca gatatttgac cggatctggg gatttgattc
    88561 tgatacgacg attacagtta ttgaagttta tatgagcaac ttacgaaaac atctgcgaag
    88621 tactggattg gataaagaaa tcaaaacctt acgtaatgtc ggttatatac tgcaaagggt
    88681 gtgatgcaat gaatggagat attacacgaa agcaacgtag tcgctttttt gcgacaaatg
    88741 tagcagcatt tgcttttatc ttttttcttt tgggattcat tactttacag atattaaacc
    88801 aatctgcata cagagaaaca gatctgtcat tagagaaaat aaattttgat tctcgaacag
    88861 tacaattaga gatacaaaga tatcagcaag gcgatccctt tttaaacccg actcaaacgg
    88921 aacaaaacag aacaaacatg gaacagccat taatggaacc atcaaatgac cgttttaaca
    88981 ctcaagtgat cttgtggtct aaaaatggtg agatattgaa taaagcagct attggtgggc
    89041 gtttcaacca aatcaaagaa ttaaaaatgg atacgaaaaa tctgaatacc atccaaaata
    89101 ttgaattaaa tgaagacagt ggctcatctg ccctctcttt ccgttcgatt acgaaaaaag
    89161 cggagacgaa tcaagatggc gttgcctaca tccaaatttt agaaaataca aatcaaatca
    89221 agaattcatt agcgactttt cgcacgatta tgattttgtg tatgattgtt ttttggattc
    89281 tctctattgg tatcagttat tacttgtcta gtctaagcat gcgccctatt attctttctt
    89341 ggagaagaca aaaagaattt gttgagaatg cttctcatga attgcgcaca ccgttaacga
    89401 ttattcaaaa tagtttggaa catcttttta ccaagcctaa tcatactatt attgaagaat
    89461 ccgaaagcat cgctcaagca ttgtcagaga cgaggcgcct cactggattg acttcggatt
    89521 tgctgacaat cgctcggaat gattctgatc agcagctgct ttcaaagcaa atgatcaata
    89581 cacaagaata tatcgaacaa cttgttaaac catttcaaga gatggccatc atagatggaa
    89641 aagagtttat tctccataac gatgcaacat tagaagtacc aattgatgaa aaaaaaatcc
    89701 atcaagtttt ggttattttg ctggataatg cattaaaata tacgaatcca gaagataaga
    89761 tcattttgga ttcatctgtt aaccataaag aatggctgat tcacgtaaag aatactggcc
    89821 cttctatcag tgaagaagat caagcaagga tttttgatcg attttatcgg gaagatcaat
    89881 ctcgggcgaa agagactggc ggatacgggc ttggcttggc aattgcaaaa caggtaatcg
    89941 aacagcatca tggacagatt tctgtatcca attatcttcc acaaggagtc gattttaaag
    90001 tccaattgcc gttgaagcct aaaaaataat gcttatccct aaaaaagggc tgtgacaaaa
    90061 atcttgtcac agcccttttt tgttgcgaat aaacggtgtt ccagaagtag cttcttcgga
    90121 aataagccga aatttcttta agctgaccac ttctgtcaca acctctttag cttacgctta
    90181 cgatttttta ttgcggtctt caatgtgtac atcaccgctt gtgtcaatat ccaattcttc
    90241 tcggctaaca tcttctgtca ctttttcaac atcttcatgt tcttctttat gaatcccaac
    90301 ttcttcacga ataactgtat gtttgcttac atctacttgc tcttctttga ttgggatagt
    90361 aatcgtgtca tcttccaatt tttcgtctgt tccctgtgaa gattgatctg ttactggttt
    90421 gcgttcgatg acgatttctt cacgtttgac cggtacttct accgtttcag tatcgttgac
    90481 cacatgtttg tggatgtcga cttctccagt tgtcacatca tgtgtattta catctaattt
    90541 ttcttctttt agttgaattg tatcatcatc tagatttggt ttgcgatcga tgtcttcagt
    90601 cttgcttgta cccattgtat cagtctcgcc aggtacgtcc atcggatcag ttcctggtgt
    90661 catattcaat ggatccgttg tattttgaaa gcctgtcgtg ccacctacgt ccattggatc
    90721 tgttccagtg ccagtttcta atccagtccc cattgtgctt gctgggctaa cagtatcttg
    90781 tgtatccatt gtatcttctg ttgtttctgg ctgacgatag ccttttactg tgatgacaaa
    90841 ttttccatca gaaatatctc ctctatattg atataaagga tcattttctg gtgtagccgt
    90901 ctcagaatca taggtatcaa aagaaaaagt atcttttatt ttttcccata aagaacggtc
    90961 ttcttcacca tccatccgat tttcatctgt ttcaacatct ataccagaca atccgtcaaa
    91021 tcctagtcta gatgctgctt catcagtagt ataaataacg atatcatctc gttcataccc
    91081 ttcgttacgc aaccgttcaa ttactgataa tgcttcttcc ctcgtactat agcttccgat
    91141 gaccgttaaa tttttctctt ccatgtaaat tcctcctagc aaatagattt atgattggta
    91201 tattgttact tataaattta ttctatagga gacgattgtt ttctacaaat atttagattg
    91261 gaatttgatt aaaacaattt aattgaaatt tgaaaacatt tatgttaatg aaagtcatat
    91321 tctaataaaa tgtcatttgt ttctatatga atttttatga aaaatttcat ataatttcca
    91381 ctcgttgtga tggtttaatt tatccaatcc atcaataagc aaacaactta tataaaaaag
    91441 gattaattct caatataatt gctcctacca tagaataaat cttcatgtaa agtaatgaag
    91501 taccaactat ttctaatact tctttaagaa ttatcccaac aatatcgtta gacaaaccat
    91561 tattgaataa atggagagcc aatcgattct gaaaaaatgt tttctaattt ttcggaaata
    91621 aaagaaagag cctcctgcca ttagaacgaa ccaaatccat ttcattgctc atgaagtaac
    91681 cacatagcta aaaagaggat aaatcaatta aaagatcaaa agaatgactg cactaataaa
    91741 ataactaaaa atgtatcttc ttacttcata tcttttagct agtacttagt taaaaatttg
    91801 cttcctaaga tcaagacaaa ctgtctatct tcatttgatg aaatgcggta aaatatagaa
    91861 aatgaacact attggaggga atttgtaatg gacagcaaaa ctagaaaaca actgcaagaa
    91921 aagttaaagc aacgtacaca cttgctccct tccgtctttc aacagttttt agaagaaaat
    91981 cgttcttccc tttcattagg cagtcgctat gaatacgcaa aagattttca tctgtttact
    92041 gattatttga gaaaagtatt ttctgaagaa gtggatgatc agctgattat ccatttagaa
    92101 aaacaagatt atcagaattt cttagctaaa atctatcgac atactcgttc gttccaaact
    92161 acagcgaacc aagaaacgga gcaattgttt gaaaatagct attacgggat ttcaaggaag
    92221 caatattcat taaatcattt tttacgattt ttgtatcaaa aaggactgat tgaagaagag
    92281 atttctcttt tgggtacaag tttaccggaa acaaccaaag cagctccgcg atatatcgat
    92341 gcagaacttt tcaaagattt tgagcatttg tttatcccga ttgaaggctt tcaaacaagc
    92401 agagaagcta gctttgaaga aaagaataga ccgaggaacc ttgcaattac tgccattctt
    92461 ctgtattgcg gattaaagat ccatgaagta gtagaactta aacgtaaaga tgtatctttg
    92521 accaagcaga ttcttaatct gaatagaaaa gaaaacagac tgaataaagt accaatacca
    92581 aaagaagcga tgccatttct ggagaactat tttaagttaa cagcacaaaa tacggacgaa
    92641 aattcttttg tttttcgttc ctcacatgat cagcaaattt ctcctcggac tattcgccaa
    92701 attttgagca aaattacagt atataaaaac gtatcgccag aactatgcag aaaaacatat
    92761 cgttattatg cagaactata tttagatgat gctgacgcgg taaattattt atgtggtaat
    92821 cgatacctct catcccattc ttttcaagat atctgggaaa agatggttga tttttcttat
    92881 cacgaattag cggcattcgt tcgggtttct tccatataaa acaaatgtat gatctttttt
    92941 tcacaataaa ctatgttatt atataaagga ttatgttacg attatcttga atttgtatat
    93001 tacttaacaa aagataatgg agtgtgaatg atggagacca taacgtattc ccctttgaac
    93061 ttatttacga attttcaaga agctgcagct aacttttccg agaccccgat tatctttgat
    93121 gagccacttt cagctttccc agaattagga cttgaaacaa cttacaaaaa atgctgcgaa
    93181 agtgtgttga aacgggctta tcaattggct catcttggag tgaaatccgg agacaaagtt
    93241 attatttata agagttccgc ttttgacaca taccttctag ctgtttctgt gtcttacctt
    93301 ggtgcagtgc ctgtcatgac ttcttatcat ctaccaacaa caacaatgga agtatttatc
    93361 gatcgtttag aagacccttt cattttattt gatgatgaga caaaaaagcg agtgagagaa
    93421 atttcaaatg gaacaaaatc aaaacagatt
//
LOCUS       DASHWW010000004        84522 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.004, whole genome shotgun sequence.
ACCESSION   DASHWW010000004 DASHWW010000000
VERSION     DASHWW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.004"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     misc_binding    complement(1..256)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(332..670)
                     /locus_tag="U2R64_000323"
     CDS             complement(332..670)
                     /locus_tag="U2R64_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEM8917171.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(672..1028)
                     /locus_tag="U2R64_000324"
     CDS             complement(672..1028)
                     /locus_tag="U2R64_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEM8917172.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(1034..2221)
                     /locus_tag="U2R64_000325"
     CDS             complement(1034..2221)
                     /locus_tag="U2R64_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEM8917173.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(2412..3257)
                     /locus_tag="U2R64_000326"
     CDS             complement(2412..3257)
                     /locus_tag="U2R64_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8917174.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3491..4456
                     /locus_tag="U2R64_000327"
     CDS             3491..4456
                     /locus_tag="U2R64_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEM8917175.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            4833..5876
                     /locus_tag="U2R64_000328"
     CDS             4833..5876
                     /locus_tag="U2R64_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HEM8917176.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(5938..6402)
                     /locus_tag="U2R64_000329"
     CDS             complement(5938..6402)
                     /locus_tag="U2R64_000329"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEM8917177.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTKEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            6648..7595
                     /locus_tag="U2R64_000330"
     CDS             6648..7595
                     /locus_tag="U2R64_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8917178.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(7806..9878)
                     /locus_tag="U2R64_000331"
     CDS             complement(7806..9878)
                     /locus_tag="U2R64_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEM8917179.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(9811..10188)
                     /locus_tag="U2R64_000332"
     CDS             complement(9811..10188)
                     /locus_tag="U2R64_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEM8917180.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(10317..10895)
                     /locus_tag="U2R64_000333"
     CDS             complement(10317..10895)
                     /locus_tag="U2R64_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8917181.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            11027..12319
                     /locus_tag="U2R64_000334"
     CDS             11027..12319
                     /locus_tag="U2R64_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEM8917182.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(12379..13497)
                     /locus_tag="U2R64_000335"
     CDS             complement(12379..13497)
                     /locus_tag="U2R64_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEM8917183.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(13511..14932)
                     /gene="arcD"
                     /locus_tag="U2R64_000336"
     CDS             complement(13511..14932)
                     /gene="arcD"
                     /locus_tag="U2R64_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HEM8917184.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(15178..16299)
                     /gene="mnmA"
                     /locus_tag="U2R64_000337"
     CDS             complement(15178..16299)
                     /gene="mnmA"
                     /locus_tag="U2R64_000337"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEM8917185.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            16703..17302
                     /locus_tag="U2R64_000338"
     CDS             16703..17302
                     /locus_tag="U2R64_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEM8917186.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(17440..18726)
                     /gene="efmA"
                     /locus_tag="U2R64_000339"
     CDS             complement(17440..18726)
                     /gene="efmA"
                     /locus_tag="U2R64_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HEM8917187.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(18997..19341)
                     /locus_tag="U2R64_000340"
     CDS             complement(18997..19341)
                     /locus_tag="U2R64_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEM8917188.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(19478..20623)
                     /locus_tag="U2R64_000341"
     CDS             complement(19478..20623)
                     /locus_tag="U2R64_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEM8917189.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(20803..21777)
                     /locus_tag="U2R64_000342"
     CDS             complement(20803..21777)
                     /locus_tag="U2R64_000342"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEM8917190.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(21857..22732)
                     /locus_tag="U2R64_000343"
     CDS             complement(21857..22732)
                     /locus_tag="U2R64_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HEM8917191.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            22862..24769
                     /locus_tag="U2R64_000344"
     CDS             22862..24769
                     /locus_tag="U2R64_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HEM8917192.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(25310..28588)
                     /locus_tag="U2R64_000345"
     CDS             complement(25310..28588)
                     /locus_tag="U2R64_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HEM8917193.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(28859..29404)
                     /locus_tag="U2R64_000346"
     CDS             complement(28859..29404)
                     /locus_tag="U2R64_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8917194.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(29416..30108)
                     /locus_tag="U2R64_000347"
     CDS             complement(29416..30108)
                     /locus_tag="U2R64_000347"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEM8917195.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(30127..30411)
                     /locus_tag="U2R64_000348"
     CDS             complement(30127..30411)
                     /locus_tag="U2R64_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917196.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(30424..30987)
                     /locus_tag="U2R64_000349"
     CDS             complement(30424..30987)
                     /locus_tag="U2R64_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEM8917197.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            31215..31877
                     /locus_tag="U2R64_000350"
     CDS             31215..31877
                     /locus_tag="U2R64_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HEM8917198.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            32001..33197
                     /locus_tag="U2R64_000351"
     CDS             32001..33197
                     /locus_tag="U2R64_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEM8917199.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(33298..34674)
                     /locus_tag="U2R64_000352"
     CDS             complement(33298..34674)
                     /locus_tag="U2R64_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8917200.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(34711..35577)
                     /locus_tag="U2R64_000353"
     CDS             complement(34711..35577)
                     /locus_tag="U2R64_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HEM8917201.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(35666..36691)
                     /locus_tag="U2R64_000354"
     CDS             complement(35666..36691)
                     /locus_tag="U2R64_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8917202.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(36709..37383)
                     /locus_tag="U2R64_000355"
     CDS             complement(36709..37383)
                     /locus_tag="U2R64_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8917203.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(37567..38460)
                     /locus_tag="U2R64_000356"
     CDS             complement(37567..38460)
                     /locus_tag="U2R64_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8917204.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(38534..40231)
                     /locus_tag="U2R64_000357"
     CDS             complement(38534..40231)
                     /locus_tag="U2R64_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8917205.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(40224..41537)
                     /locus_tag="U2R64_000358"
     CDS             complement(40224..41537)
                     /locus_tag="U2R64_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEM8917206.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(41537..45055)
                     /locus_tag="U2R64_000359"
     CDS             complement(41537..45055)
                     /locus_tag="U2R64_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEM8917207.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(45348..45806)
                     /locus_tag="U2R64_000360"
     CDS             complement(45348..45806)
                     /locus_tag="U2R64_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8917208.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(46104..46622)
                     /locus_tag="U2R64_000361"
     CDS             complement(46104..46622)
                     /locus_tag="U2R64_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEM8917209.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(46624..47241)
                     /locus_tag="U2R64_000362"
     CDS             complement(46624..47241)
                     /locus_tag="U2R64_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEM8917210.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(47238..48092)
                     /locus_tag="U2R64_000363"
     CDS             complement(47238..48092)
                     /locus_tag="U2R64_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8917211.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(48089..49000)
                     /locus_tag="U2R64_000364"
     CDS             complement(48089..49000)
                     /locus_tag="U2R64_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8917212.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(49041..50375)
                     /locus_tag="U2R64_000365"
                     /pseudo
     CDS             complement(49041..50375)
                     /locus_tag="U2R64_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            50583..51413
                     /locus_tag="U2R64_000366"
     CDS             50583..51413
                     /locus_tag="U2R64_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HEM8917213.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWEYAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(51657..51975)
                     /locus_tag="U2R64_000367"
                     /pseudo
     CDS             complement(51657..51975)
                     /locus_tag="U2R64_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(52097..52291)
                     /locus_tag="U2R64_000368"
     CDS             complement(52097..52291)
                     /locus_tag="U2R64_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917214.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(52796..52981)
                     /locus_tag="U2R64_000369"
     CDS             complement(52796..52981)
                     /locus_tag="U2R64_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917215.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(53831..54172)
                     /locus_tag="U2R64_000370"
     CDS             complement(53831..54172)
                     /locus_tag="U2R64_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8917216.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(54172..54402)
                     /locus_tag="U2R64_000371"
     CDS             complement(54172..54402)
                     /locus_tag="U2R64_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8917217.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            54689..55027
                     /locus_tag="U2R64_000372"
     CDS             54689..55027
                     /locus_tag="U2R64_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917218.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(55232..55471)
                     /locus_tag="U2R64_000373"
     CDS             complement(55232..55471)
                     /locus_tag="U2R64_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEM8917219.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(55447..55794)
                     /locus_tag="U2R64_000374"
     CDS             complement(55447..55794)
                     /locus_tag="U2R64_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEM8917220.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(56527..57108)
                     /locus_tag="U2R64_000375"
     CDS             complement(56527..57108)
                     /locus_tag="U2R64_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8917221.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(57291..57917)
                     /locus_tag="U2R64_000376"
     CDS             complement(57291..57917)
                     /locus_tag="U2R64_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8917222.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(57939..59270)
                     /locus_tag="U2R64_000377"
     CDS             complement(57939..59270)
                     /locus_tag="U2R64_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEM8917223.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(59425..59826)
                     /locus_tag="U2R64_000378"
     CDS             complement(59425..59826)
                     /locus_tag="U2R64_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEM8917224.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVFEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(59912..60118)
                     /locus_tag="U2R64_000379"
     CDS             complement(59912..60118)
                     /locus_tag="U2R64_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917225.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(60213..61715)
                     /locus_tag="U2R64_000380"
     CDS             complement(60213..61715)
                     /locus_tag="U2R64_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HEM8917226.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(61733..62188)
                     /gene="argR"
                     /locus_tag="U2R64_000381"
     CDS             complement(61733..62188)
                     /gene="argR"
                     /locus_tag="U2R64_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEM8917227.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(62286..62903)
                     /locus_tag="U2R64_000382"
     CDS             complement(62286..62903)
                     /locus_tag="U2R64_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HEM8917228.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            63124..64497
                     /locus_tag="U2R64_000383"
     CDS             63124..64497
                     /locus_tag="U2R64_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8917229.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            64572..65684
                     /locus_tag="U2R64_000384"
     CDS             64572..65684
                     /locus_tag="U2R64_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEM8917230.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(65756..67393)
                     /locus_tag="U2R64_000385"
     CDS             complement(65756..67393)
                     /locus_tag="U2R64_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HEM8917231.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(67561..68169)
                     /locus_tag="U2R64_000386"
     CDS             complement(67561..68169)
                     /locus_tag="U2R64_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8917232.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(68554..69705)
                     /gene="queG"
                     /locus_tag="U2R64_000387"
     CDS             complement(68554..69705)
                     /gene="queG"
                     /locus_tag="U2R64_000387"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEM8917233.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(69724..70476)
                     /locus_tag="U2R64_000388"
     CDS             complement(69724..70476)
                     /locus_tag="U2R64_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917234.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(70617..71567)
                     /locus_tag="U2R64_000389"
     CDS             complement(70617..71567)
                     /locus_tag="U2R64_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEM8917235.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(71568..72407)
                     /locus_tag="U2R64_000390"
     CDS             complement(71568..72407)
                     /locus_tag="U2R64_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEM8917236.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(72404..73150)
                     /locus_tag="U2R64_000391"
     CDS             complement(72404..73150)
                     /locus_tag="U2R64_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEM8917237.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            73388..74758
                     /locus_tag="U2R64_000392"
     CDS             73388..74758
                     /locus_tag="U2R64_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8917238.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(74813..75709)
                     /locus_tag="U2R64_000393"
     CDS             complement(74813..75709)
                     /locus_tag="U2R64_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8917239.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(75823..75993)
                     /locus_tag="U2R64_000394"
     CDS             complement(75823..75993)
                     /locus_tag="U2R64_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917240.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(75990..76667)
                     /locus_tag="U2R64_000395"
     CDS             complement(75990..76667)
                     /locus_tag="U2R64_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEM8917241.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(76758..77663)
                     /locus_tag="U2R64_000396"
     CDS             complement(76758..77663)
                     /locus_tag="U2R64_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEM8917242.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            77838..79292
                     /locus_tag="U2R64_000397"
     CDS             77838..79292
                     /locus_tag="U2R64_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8917243.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            79308..80339
                     /locus_tag="U2R64_000398"
     CDS             79308..80339
                     /locus_tag="U2R64_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEM8917244.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            80346..81533
                     /locus_tag="U2R64_000399"
     CDS             80346..81533
                     /locus_tag="U2R64_000399"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEM8917245.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            81689..83071
                     /locus_tag="U2R64_000400"
     CDS             81689..83071
                     /locus_tag="U2R64_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEM8917246.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            83043..83429
                     /locus_tag="U2R64_000401"
     CDS             83043..83429
                     /locus_tag="U2R64_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917247.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(83629..84297)
                     /locus_tag="U2R64_000402"
     CDS             complement(83629..84297)
                     /locus_tag="U2R64_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEM8917248.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        24193 a        17719 c        15074 g        27536 t
ORIGIN      
        1 aaaaggacga aagcttgaac ttccgtgtta ccaccttgat ttaccgttac ttcgcaataa
       61 cagcctcttc cagtacttgg acttagcttc tttccgtata ctgtcgcgct gtaacgggca
      121 ctcccgtagt aagtttgctt acgctcgctt actctgctct aagaccatct tccatctcat
      181 tttcgttacc cattttcagc aaacagggct ctcttcaaac gtccgtgaca tgtactcttc
      241 ttttcaaagc tttctcgttt catataggat tgcttatgat tatagcaact ggaagaatca
      301 gtgtcaactt ttttcaagtg attttctgat tttataattc gtcaaattct tttggatcaa
      361 catctttgaa acttaagatc cacgcattca tttcatctga atcattcaag atattgatat
      421 cttcaccgat tttatcatta acagaagaaa ctgtacccgt tagcgggctg gcaaattcat
      481 tgaccgcttt ttccgcttca acttcgatca gaggttcatc tttttttagc gattgtcctg
      541 cttttggcag attggcaaac gtgatgtctc caagttcttc ttgcgcttca tttgtcaaac
      601 caacacagta ttcttttcca ttaaataaga tccaaaggtt gtcctttttc ttcaaatgct
      661 tgcctgccat tttatatcag ttctccttca taaatttttt cattgaatcc aattgcaaca
      721 agctggtcct ctcgtaagat cagtggtcgc ttgatcagca taccatctgt cgataagact
      781 tggctcgctt ttgaagccgt aaactcgcct acttgatctt tcagtccaag ttcccgatat
      841 ttcatcccgc ttgtgttgaa caggcgacgg attggtactt gactcgtttc tagccaagtc
      901 tcaatcgttg aggccttcgg tacttctttg atcatatcaa cggtttgata actaacgcca
      961 tgctggtcta accacgcttt ggcttttttg catgttgaac atttcgggta ccagtaaaag
     1021 gtgtacaatt ttcttacctc cttgaagatc ttgcaggtgc ttcattttgg tatctcatcg
     1081 ataatatcaa cccgataccg atcatgttcc ctaaaatcga ggatcctccc tgactaatga
     1141 aaggcaatgg gatccctgtt aaaggaagta atccgatatt tgctccaata ttctcaaaga
     1201 catggaacag cagcatcatg atcaaaccgc ttgcgatata ggcgtaaaat tcattattcg
     1261 tatcgaaaca cacccgaatc atacgataga ttaaaataaa atacaagaaa atgacgaatg
     1321 caccaccgat aaagccgaag ttttcaccga taacggtaaa aatcatatcg gactcacgaa
     1381 caggcacata gatattgctt acgttgaatc ctttaccaaa caagccaccg gtaccaattg
     1441 ccaaaagtcc ttgggccggc tgataactca ttcctgacgt atcatggaaa gggtccagcc
     1501 atgaatcaat acgtgcaaac tgataagatt tgaatccaac tttataaagc aagtctcttc
     1561 cgccttcagt cgtaaccaag aagatcgttc ctgctccaac gactactgcc aagattacta
     1621 caggtgcgat gatgcgccaa gagattccag acatcaggaa aatcccgcca aagatcgcaa
     1681 gaaagacaag catcgttcca aagtcatctt gggccatgat caatgctaaa accggtattg
     1741 tcacgatcaa gagcttccca atcagccaaa agtccgattt catcgtccgt tcttttactt
     1801 gcgtattatg tttagttacg atcagtgcca tcatcaagat gtacgcaatc ttcatcaact
     1861 ctgctggctg gaaagtaaac gcaccgaatc gaaaccagtt tttagaccct gttgaagcag
     1921 ctaaattctg atcatagaat ttgagcaaga gtcccattac cactaacccc aaaccataaa
     1981 ggtaaggagt cagtttccag atccatttgg aattcaaatg catgatgaca acgattgctg
     2041 ccgctccaac taaataccag acaacttgca tccctacgcc tttcaagact gctggattgt
     2101 tcggatcatg gctaagtgct acatataatg agagcagacc aatcaaacat aacagaaaga
     2161 ctggtaaaat cacgccataa tcaatacgat tatcgttcga agcttttaat tttttttcca
     2221 tgtttcatcc cttttcttaa aaaccatact gctgattatt atagcggtcc agttagataa
     2281 tggaaagtct ttccatagac atttgggaaa aattaacttt ccgtttgtgc agttgcttga
     2341 gcaaatgcag tacaaaagcc tactgcttat ctttagtgta tcatagaact ttttttgata
     2401 catgcaatta tctaccagct gagattctcc tcgctgtgag aagtttctgt gctttcattg
     2461 tatcgaagga tctcttcggc aatctctagc agctgatcag aaaccagatt ggttcgttgg
     2521 atgaaataaa aatatcgatg gaaattcaac ggagtcattg gcacattttc tggaacagag
     2581 cgcttagaca aaatcgagcg accgattcct tccttcagca acgcaacaat tacatcgtta
     2641 cttttcacga tcatcttctt atcttggata ttcatctctt caaaataacg ctgcgtgtaa
     2701 tgaaaaacac cagagtttgc ttctcttaca agccacaatt tgctttttgg gtccccagcg
     2761 atgactagct ggtcttccat caaagagtat ctttgtacgc cggaagtctc taatggcttt
     2821 tcgataaaac caaaatcgga ttcatgtttc gctacttgtt ctaatgattc atgagaattc
     2881 gtgatttcga tctcaaaatg cactttagga aaccttttga tcagatgttt catcaactga
     2941 ggcaaaagat agacagcaaa ggtgtgggaa gcaacgatcc gacatacttc ttcttcattt
     3001 tgttcattga gcaatttttg ctgagtttct tcccattctt ctaacaaaac cagtgtccgt
     3061 tcatataata agtcggcttg cttagttgga agcatctctt ttcttccgtt acgttgaaaa
     3121 agatcgatat tcaattcccg ctccaactgt ttgatttgat tcgagactgc tggttgagat
     3181 aaaaacagta cttctgctgc tctggaaaaa tttcttgttt catatactgc tcgaaaagtc
     3241 gttaataact taaacatggc accacttcca taacttttta tgataattac tataaaaact
     3301 atttgattta aatatacaaa aaaccatcta taatagaaat gtacaacaaa acagttgctg
     3361 atccaactag taacttagat gaagacaatc agctgtctgc ttgctcgtaa tcatacattc
     3421 ctattcattt tacaatgtat tcgttcatct tggtactaaa atctattaaa taaaaaggag
     3481 aatattatat atgaagaact ttttgaaaat tattccgatc ccgatctgcg ggttgatcct
     3541 tgggttagct tcccttggaa atctgtttaa agactatcac catgttgctt taggcaatct
     3601 aactggcggt atctctatga ttcttatgat attcattttt gttaaattgt ttatcttatt
     3661 cgaacacacg aaacaaacgt tgcatgatcc aatcatcgcc tccgtttcac caacttttac
     3721 gatgtcactc atggttattt gtacttattt tgtttcatat gaaagtattg caccaattgt
     3781 caaattcatt tggctgtgcg ctgttatctt ccaagtgatc cttgtctttt atttcaatta
     3841 tcaccatgtt atcaaagctg atctttcaat tgaagcaatt tatccaagct ggtttatcat
     3901 ttacgttgga tttggggtca tcactgtaac tgccgggaac ttcttcccac ttattggaaa
     3961 aattttcttt tggatttcat tgatctgcta tgcgttctta ttgccgatca tcatcaaacg
     4021 tgtctttttc gtaagaaata tggctcatcc gacacgtccg ctgattacga tcgttgcagc
     4081 acctggttct ctttgcctaa caggttatct taaaaacttt gctgaaccta atttttatct
     4141 tgtcgtagca ttgttcgctt tatctcaagt attgtatttc gttgtgctgt ctatgcttcc
     4201 acgtttgttc aagcttcgtt tttatccaag ctatgcagcc tttacattcc cgcttgttat
     4261 ctctgcaaca gctatattta ctactgttca ttacttcaac agtttaggta tctatagtag
     4321 cgtattggat ttcttaaaag ttgcggaatg tctgtttgca agtgtagttg tcttctacgt
     4381 tcttgctcat tacgtacgtt tcttaattaa agaacatagc aaacatggaa aatttgtttc
     4441 taaaaaaatc gcttaataat cgattcaata ggttgtgaaa aagctgttct gcatcaagta
     4501 ataagaacgg ccaaacaaaa acagctgttc atgtttttgt actggttggg cttattaccg
     4561 cagatgcaag cttttgaaca ccgtttacca agaggtcgta aaagaagtgg tcagcttcaa
     4621 gaaataagaa ggaatttacg aaaattgctt ctcaaatttt tgtgaaattt cggcttattt
     4681 ccgtagaagc tacttctgga acaccgttta ttcgaaacaa gaggtcgtac aagacttttg
     4741 tcacgacctc ttgttctttt gtcaaaatac tggtttagtg ctactatgtt cgagtatgct
     4801 tttagtattt attgacgaaa ggaaccgatc aaatgaaatc attgtcacat ccaataaaat
     4861 ctgtaaagga ttcagcggtc cgcgaaatct tacccggttt actgctttct tttgccatcg
     4921 ctgccttcag caggcttctt gctatttatc tgccacagtt aggtggagcg actattgcta
     4981 ttttattggg tattttatta ggaaatactt tttttaaaca gcctgttcta gcaatcggca
     5041 caaaatttgc tgaaagcaaa ctattagaat tctctgtttt tttactaggt gcaactgtca
     5101 cagctcaaac gattgctcaa attggtgtaa aaggaattgt ttttgtgtta ctgcaaatgt
     5161 cagtcactat catcggtgct tacttgattg gtaaaaaact gcaattcagc gatacttctt
     5221 ctttgatgat ggctggagga aacgctgttt gtggttcttc tgctattgct tcaatcgccc
     5281 cttccatcca tgcgaaagag gaagaaaaag gacagatcat cacactagtc aatctactgg
     5341 gtactgtgat gatgttgact ctcccttttc ttggattaca gttgtttggt ggaaatctca
     5401 ttgaaaaaag tgcacttttg ggtggtacac tccaatctgt tggtcaagta gtcgctgggg
     5461 caagcttact tgacaattct gttgtcgaat tcgccatgct atttaagatt ctacgtatta
     5521 tgatgctcgt tgttgttgtc tatctgtttg aaaaattcat gcacaagaaa caaccagctc
     5581 tgtttgaaac gccaactgat acgcagaaaa aacgaaaatt accgcttcct tggtatgtat
     5641 tagggtttgt gatcttttgt ttggtcaaca gcttgttttc tttacctgta gttattgacc
     5701 aatcggcaca ttttatcagc agctggtttg agatcactgc tttagcggca attggtctgc
     5761 gtttagactt tgcaaaattc atgaaagaag gtacacgctt cttatcttat ggattagctg
     5821 tcgggcttct ccaaacagtg atggctttac tatttatttg gctgatcaaa gtttagaatg
     5881 aacatgaaaa aacagttgtg attctcgcat ggaacaatgt ccgaatcaca actgttttta
     5941 attttgcaga tatccttcta acaacaacaa ttggcgtttg atttcaaccc catctattgc
     6001 gtttcccata tatcctgtca gttttccatt ttgcccgatc actcgatgac aaggaataac
     6061 gattggcaat ggattggttc gatttgcctg cccaatcgct cgcacagctt tcggactatc
     6121 aacagcaacg gctacttctt tatacgttcg gatttctcca taaggaatgg tcgacaaagc
     6181 tttccagaca ttttgctgaa aaggcgtacc tctctttata gataaaggaa catcaaattc
     6241 ttttcttttt cccgcaaaat attcttcaaa ctgttctttt gtgcgcgtta aaattcgctg
     6301 attcgctgat tcgctttctg aaattggctg aaaagataca gcagtcaatc cggattcatc
     6361 tgcatctaac cataaaaagc cgataggtgt gtgtattttc attttgtttg ctcctagtca
     6421 atagactgga acttcctcct ttttctctat ccaaaactac ttgccaacta ataaaaattg
     6481 ttcttaaaag tttgataaac cgaggaaaca tggtaaacta aatacgttag tttacaaaaa
     6541 gaatacctgt tcttttacgt aaaatcaaat tttaaaggtg ttatttaagg tttattaaat
     6601 tttgaatgta aaccatatat aaacatacga ttgaaaggat agaaacgatg aaagtatcaa
     6661 ttgttgtccc atgttttaat gaagaaaaaa ctgttcctct tttttttgat gaggttgaaa
     6721 aattcaaagg tgcccatgag ttcgaatatt tgtttattga cgacggatca aaagacggta
     6781 cgttagcagc aatcaagaag ctagcctcag cttatcctta tgtccgcttt gtctcatttt
     6841 ccagaaattt tgggaaagaa gcggctctgt acgctggatt gcaagcttct acaggagatt
     6901 tagtgaccgt gatggatgtt gatctgcaag atccgcccga actgcttcct gagatgatca
     6961 accggatcac tacttctgat atcgattgtg tcggcacccg gcgttcgact cgtgaaggcg
     7021 agcctgcgat acgcagtttc tttgcgaaaa aattctacca gttgatcaat aaaatcagcg
     7081 atacagaaat ggtcgatggc gctcgtgatt tccgcttgat gactcgtcaa atggtggatg
     7141 ccgtcctaga attaacagaa tacaaccgat tttcaaaagg attatttagc tgggtcggat
     7201 ttaaaacaga atatatttct tatgaaaacc gcgaacgtgt ggctggcgaa acatcttggt
     7261 ccttctggaa attattcaac tactcgattg atggtatcgt gaacttctcg gatgcaccgt
     7321 taacgattgc ttcatttatc ggcgctttgt cttgtgtcgg ttctggtatt gcaattttgt
     7381 tcattatttt gcgggcattg ttgtttggtg atcctacatc aggatggcct tccatggtct
     7441 cgatcttcct gttcattggt ggaatccaat tgttatgtct tggaatcatc gggaaatata
     7501 ttgggaaaat cttcttagaa acgaaacagc gtcctgttta tatcataaga gaaacagaaa
     7561 aagtgaagcc aaatgaattg aagcctcacc aataatatac gtcaaatgaa gtaaacattt
     7621 ttttaaatga aaaaggactg tgacaaaagt cttgtcacag tccttttttc cgaataaatg
     7681 gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt tgagaagcaa
     7741 ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctatcacaac ctctttcata
     7801 tcttattact tcttcattgc tgcttttagt gctgctgcta atgggctttc ttctggttct
     7861 tctgcttgtg catatttttt cagcaagcgt cgttcttcat gtttggtcat tttcttcttc
     7921 tgctcttttt tatcaagcaa tttttctgtc gttccatcgt atttacaacg gaaataagca
     7981 ccgtttttac cttcgatgat ttccattttc cggtgacatt gcgggcatcg atgattagag
     8041 acttttggat cttttcttct gcggtagttg caatctgaat tggtgcagac atagattttg
     8101 ccgtcacgtg tgtttttctc gcgcagattg gccccacatt ctgggcattt cttttgggta
     8161 atcgagaaat cttgatattc ttgtttgctt gatttgatct cattcaccaa gcgttttgtt
     8221 tctttttcga ttccattcaa gaaggttcct gcttgtttct ttcctgcagc aatagcttca
     8281 aggtcttttt cccagctttc tgtcaaatct ggtgttacta aagagggatt taccaatact
     8341 aataattgct tacctttagg agatacttgc agtccttgag gggtacgttc catcagttca
     8401 gatttgatta gtttctcgat aatctctgca cgcgtagctg gggttcccag actgtatttt
     8461 tccatttgac caagcaagct tgcttctgac aatggtttag gcggtgcaga tagttctttt
     8521 ttgatggcga aatcgggatt gattctcatt cctttttccc atttgactgt ttccgtctca
     8581 gtttcagttt cgcctttcca tcctgcttgg acgacacgat tttgccgaaa aatgaatcgt
     8641 tctttaccaa attcaaccgt aacttttgtt tggctgactt tatggggttg agcaaacagt
     8701 cctaaaaaac gagagacaat catttgatag atttttcgct cttcattact taatttttca
     8761 taacgtgctc tgttttcagt tggcaaaagt gcatggtgat cggtcacttt actgtcttgg
     8821 aatacttttg tctgttggac gatggctccg tttttcaaat actgcttgac ctcaggagca
     8881 aagtcgctga ctgcttgcaa tcgttctttc atcgtacttt tcatgtcatt tgtcagatat
     8941 ttgctgtctg tacgcggata agtaacgatc ttatgggtct catacaaact ttgtacaaga
     9001 cttaatgttt tctttgcaga atagccatag cgttgattgg cttctctttg gatctctgtt
     9061 aaatcataag gcaatggcgc agattccgtt tttaattttt cttggacttc tgtgacagtt
     9121 cctttgcttg tactgatcaa ttgaacaagt ttttgtgctt cttcttgtgt ttttaaagca
     9181 aattgatttt tttgaagcat tttggcttgt tcttttccag cttgcaacgt gatcgtgaaa
     9241 tacgtttgtg gacggaactg ctcgattttc ttttcttggt ctctcactaa tgctagtgtc
     9301 ggtgtctgca cacggcctgc tgataaatta tccgcgtact tcacagttaa ggctctggtc
     9361 acattcaatc ctaccagcca gtccgctttt gcccgggcaa gagcagattc atacaatgca
     9421 tcatattctt tcgcaggtct tagttgcttg aatccagttt tgattgcttt atctgtttga
     9481 gaagagatcc ataaccgctt cactggttta ttgaaatgca catactctaa gatccagcga
     9541 gcaacaagtt ccccttctct tccggcatct gtcgcaatga ctgcttctga gacatctttt
     9601 cgctgagcca gctgcttgat tgcttttaat tgatgtcctg ttttaggaag tggtttgatt
     9661 cctagttttt tagggatcat tggcaacgtg tccatttgcc agctctgcca ttccttattc
     9721 agatcttccg gcattttcaa tcctaataaa tgaccaaggg cccaagtaac gatcaccttg
     9781 ggtccttcat aataattttt gtgcttttga ttagcaccaa gcaccttgct taggtctttc
     9841 gcaacgcttg gtttttccgc tagaattagt tgtttcataa aattcctttc tgctttctac
     9901 tgtgatgggc tgatgatttt tcaacaacgc aagtcccttg tattgctgta aatcatcgtc
     9961 acactcttca caccagcgct catctccgtc attccaaaag gcgctgagaa agttactttt
    10021 tgcattgata tattcataat tttgatggat ttcgttccat tgtttttcgt acgcttgtcg
    10081 tgcttcttcg aaagactcga atgtttcttc ttcttcaata tcttcttccc agtcttcaaa
    10141 aaaccaccaa ggctcattgt ccccgaacat ggtaattact tgatacatac tcgtgctcct
    10201 tctttcagct tttctagact catcttagtc acttttcaag aaagttgcaa gaattttctc
    10261 ttataaaagg gtcatttaat gaacatctta aaattgttac aaatgaatct gattgtttaa
    10321 ggcaaagtag cgataaagtt attgatcatc caaaaatagc tgtcttctgg atcgattgtt
    10381 ggttcttttg taaagtatcc taaaaaacgt aaggaaagat aaccgtggat catactacga
    10441 agttccctgc ttcgatgaac tttttcttct ttcgttaatt gaaaagcctc aaatatctgc
    10501 aaaatgatct gattcgtttc atggattcca tctaataaaa cagcttcatt ggtatgcggt
    10561 acactgatca gtaactcata cactgcttga tttgaaaaag caaaggatcg ataagtttct
    10621 gcatagatct gcagtgcttc ctgaccactt tttcccacaa gagcccgtcg cagctggtca
    10681 ttaagttcct gcagaagttt cgctgttagc gctgttttga catcacgaat atttttgaaa
    10741 tggttataca gcgagggagc cttgatatcc aagcgtttgg ctaaatgctg aaaggttatt
    10801 tgctgaacat ccatctcttc tgctagttct cgaaagcagt cgatgatttt ctcttgagac
    10861 agatttcttt ttttcatttc catgtttcct ctcataaaat aaatccttca ctctttcagt
    10921 ttaccacgaa aaagaaagag aaaaaagaga ctttcattga taaactacat attgtagttt
    10981 ataataaaga gctgtagatg aaaattttca gaaagaagga gtctaattgg ctgcaagaat
    11041 aaaggaaaaa ttatttagga aaagagaaac ttgggaacaa aacttgtttg tcttatggtt
    11101 tggaacattt atggctggta tcggatttag tttagtcatg ccttttatgt cactttacat
    11161 agatacgtta ggtaattata gtacgtcaca attgaacttt tggagcggat tgactttttc
    11221 atctactttc ttggtgacta cgcttatctc tccttggtgg ggaaaattag ccgaccaaaa
    11281 aggaagaaaa ttgatgctgt tgcgtgcttc attaggaatg gcaatcgtca tttctttgat
    11341 gggttgcgtg actagtgtgt atcaattagt cgcattgcgt ctgcttcaag ggattttttc
    11401 tggttatatc agtaatgcca ctgcccttgt cgcaactggg acgccaaaag aaaaaagtgg
    11461 tcaagttctt ggaaccttag caactggttc tgttacagga acattacttg gaccgcttct
    11521 tggcgggatc tctgcttcag cgtttggcta tcgccctacc tttttcatta cagggatcat
    11581 cttatttttc gtcttcttgt tgagtctgtt tttcgtccat gaaaaatttg tcccagtgaa
    11641 aaaagaaaac atggtttctg ccaaacagat tttcaaagac ttgaaatatc cacacgtcgt
    11701 catcggtatg ttcgtcacaa cgatgatcat ccaagcatcc aacaattcca ttagtccaat
    11761 catcagtctg tacattcgcc aattgctgca tggacatggg aatgttacgt tgatcagcgg
    11821 aatcattgct tcgatacctg ggattgccac tttgatagcc gctccaagat ttggtcgctt
    11881 aggtgacaag attgggagtg aaagaatact tgcgattggt ttgggttttg cgattctggt
    11941 ttatatccca atggcattcg tcacgaatgt ttggcaatta gctgccttac gttttttgat
    12001 tggtatctct gatgcttgtc tgctccctgc tgtccaagca ttgatcacaa aatattcgcc
    12061 tcatcaagct gctggacgga tcttcagtta taaccaatct ttccaagcaa ctggtaacgt
    12121 agtagggcct atgatcggct ccagtgtttc cagtgcattt ggttatcgtg gcgtctttct
    12181 ttcgacttct cttcttgttt tggtcaactt cttgcttgta cgacacaata cacaagagat
    12241 ccatcagcaa gaaactgcag aagaaaaagc ttcaggagtc tccatagctt cagggcactc
    12301 tccttctcat agacaataag cgtaaatgaa aaacactgct tgaacagttg tcacagactg
    12361 tccttgcagt gtttttgttt aggcctgttt tttcaagaac tcagataaga ggaataatcc
    12421 cttttccaag gtttcttttt tacaacagta acctagtcgg gcatgcttcg gtaaatcaaa
    12481 ggcacttcct ggtactaata gtactcctgt ttcttctaat aaattgatac aaaatgtctg
    12541 gtcatcttct tcgatggcta atttaatgaa agaagtagag acgtaattgg gagcgacaag
    12601 ttcaactttc ggttcattgg ctacccattg ttttaaaatc acaaggttct ctgtaatgat
    12661 ctttttgttt cgcgccaata ttttttcttt attcttcaat gcatgtacag caagatcatc
    12721 tgacaggact ccgccgcaaa tcatcgtgta gtctcgatac tttcgaaaaa cttctgccaa
    12781 ctcaggtcca gtagctgtcc agccaatacg aatacctgga atggagtagg ttttggatag
    12841 ggaattggtt gctatacctt tttcatagac atctacgatc gacaagaatt cacctttatc
    12901 cgttaaaggc gcatatactt catctatcaa tacatatgca tctactgtac gagcaatttc
    12961 tgcgattttt tctaaagttt tccgatctag caatgtgcct gtaggattgt ttgcactatt
    13021 caaacagatg atttttgttt caggtttgac taaggcttct agctgttcta aatcaaactg
    13081 ccaatcttct tcttccttca aatgaacaaa gtcaacagcg gcacctaaag atttggggat
    13141 gtcatataat tgctgataag taggaagcat cgaaacaaca tggtctcctg cttccactaa
    13201 cgcgtataga gctaaaagat tagcaccagt cgctccattc gtttgtaaga tgttttccgg
    13261 atcgacggtt tgataaagag aagcgacttc ttgtttgaaa acatctgatc cttcgatcca
    13321 gccatagtcc aatggttcgt ttttgcgttt ttcgaaaaat ttacttacgc tagtcccatc
    13381 taagccaacg agttcgtcta atgtcaatgc ttcgatcgag ctttgtgcaa tatcatatac
    13441 cgctttcttt tcccatttat ttagccattc ttctacaccg aaatttgcga ttttcatgtt
    13501 tctttccccc ttatatcttg atccagccta cagcaagcaa cccgattgaa agcagtgcgg
    13561 ccacacaaat cagcccaatc attacttttt cttttcccgt aatttgatgt ttggtttcac
    13621 gacaagcgat ccagtagaag caaaaaccag gaagataggc aatactacat aaaaggacat
    13681 aagaaaatcc tgctaaaatg atgcccatca attcaaaaac tacagcaatc ccaccgatca
    13741 ctacttgttt tttgattcct tcttttaaag aaaactggac ttgatagatc ccgacaagta
    13801 gataacaaat caaaattgcc gctgtacata aagaataggc aaattgatag gcataatcag
    13861 taactaagaa agtcaataag aatagattag tcaagattgc agtaacaact aacgaataag
    13921 ttggggcatt ttttttattc gtttttcccc aacctttcgg caacagaccg tctcgagcca
    13981 tcaacatcgt tgtttctgct gggagcatcg tccaagacaa ccaagaacca atgatcgaaa
    14041 taatcaagcc gatattgatc agcgctgctc cccaatttcc cacgattcct tttaaaatat
    14101 ttgccatagc aggttgtgaa atagttgcta actcttcttg agataagacg ccgtatggca
    14161 agatcgaagc aaggatatag ataaacaata aacaaagcag accaatgatc gatgcttgct
    14221 gggcttctga acgtttcttc gcgcggttgg ctaaaacact tgcgccttcg atccctacaa
    14281 agacccacat cataaccatc aaacaacctt taatctgcaa ccagatcgtt ccttgctgcc
    14341 ctgttccatt cactagatta tcagatacgt taccccaaaa atcagcagtg aatatattca
    14401 ctttaaatgc gataaataca aatattaaaa ataggaataa tggcactaat ttacagatcg
    14461 tcacgattgt attgatgacg ctcgctcctt caactccatt gtttactaat aaagtcagac
    14521 cccaaataaa aatacttgca aataaaatag aaggaacatt ttgtccacct ttgaatatcg
    14581 ggaaaaattc tcccatggcg ctcatcagca tcgttgcaaa agcaacattt cccagccacg
    14641 cagacaacca gtaaccccaa ccactgatga agccacctaa tttaccaaat gaagcttccg
    14701 cgtaaccgaa aataccacca tctagatctg gacgcttttc tcctaaatga ttcagcgata
    14761 ataccaaagc taaaatacca atcccaacga ttatccatga aaggatcgct ggccctggag
    14821 ctgcagaact agccagatca cttgtgatcc caaacacacc gcttccgatt gacgaactga
    14881 caaccagagc aaccagtccc catttgctaa tacccgtcga tttcttttcc atttccatca
    14941 ccctcactta taaaattgaa caaatcactt gcaaaagatt cccttctatt ttgcaactgc
    15001 tcttgcttaa caaaaagcaa ctttattcat attattggat attatgaact ttttacacaa
    15061 gtatttcaag tataaaatga ataaaaatta attttattgc aaaaaaacag ctatgctatc
    15121 caaaagaaaa ggtgtttctt ttgttagcca tagctgtttt gattcattta atatcgctta
    15181 aacgtattgt aaaacttttg tttcttgata tgcgtggtcg atcaaaccac cacccagaca
    15241 ttccattcca tcataaaata caactgcttg tccaggagtg attgcacgta caggttcgtc
    15301 gaatacgact tctgcacgat tatcatccaa taagcgaact gtcacaggaa cgtcttgctg
    15361 acgataacgg aatttcgctg tacacttgaa ttcttttggc attggttcat tcgtcgtaaa
    15421 gtggatttca cttgcatcca agcttgtggc atacaatgca ggatgatgga acccttgccc
    15481 cacatataat gtgtttgtcg ctagatcttt tcctacaaca aaccagggtt cttgcgaatc
    15541 tcctccgcca ccgatcccta gtccttgacg ttgaccaatc gtataataca tcaagccagc
    15601 atgttgtcct ttgacttcac catcaagagt gaccatattt cctttttttg ctggcagata
    15661 gttgctcaaa aattgtttga agttcttttc accaataaag cagattcccg ttgaatcttt
    15721 tttcttagca gtcgcaaggc ctgcgcgttc agcaattgcc cgtacttctg atttttccat
    15781 gccgcctaga gggaacatcg tttttgaaag ctgttcttgt gataattggc taaggaagta
    15841 agtttgatct ttattattgt ctactccacg aagcatgtgg accacgccgt tttcatcgcg
    15901 agtgacttgc gcataatgtc cagtagctac ataatcggcg ccaagatcca ttgcataatc
    15961 caagaatgct ttgaatttga tttctttgtt gcacatcacg tctgggttag gtgtacgtcc
    16021 tgcgcggtat tcggctagga aatattcaaa tacacgatcc caatattctt tttcaaaatt
    16081 cacagagtaa taaggaatcc cgatttgagc agctactttc gctacatcct tataatcttc
    16141 cgtggccgtg catacaccgt tttcgtccgt gtcatcccaa tttttcatga atattccgat
    16201 cacgtcgtat ccttgttcct ttaacaaaag tgctgttaca gatgagtcga caccgccgct
    16261 catccctacg acaacgcgtg ttttgctgtt gtctgtcatg atatcaccat catttcaatt
    16321 agattctgaa acatctacga gttgaaggtc gcaacttttc agtattttac attatacgtc
    16381 atatttctga aaatttcatc ccttaattat caagtcgtaa aaatactgtt ctactggacc
    16441 tattcagtac acaaacatga tagtcaacca aaaaatcact catcttttga gcattcgata
    16501 taaaaaattg gcatactcat aaaaagggcc agcctttcgg caataaggaa taattttata
    16561 aattgtgaaa aactattttt caaaattgct tcttatcgct taaagctgca cgtctcattt
    16621 acaacctttt ctttttagat gttatgagtt gctcagataa gtgattttgt ttactctaag
    16681 aaaaaaggga ggcaaaagat acatgaatta ctttatcagt gatatgcact ttttccatga
    16741 acacttatta ggaaaaaacg actttgctcc gcggctcttt gcaaatgtgg atgaaatgaa
    16801 ccaacagttg atcactagct ggaatgcagt aataaaagaa accgaccatg tttatcatct
    16861 aggcgacctt gctatgcatc cgcaatatga aaaagcaaat gcagaaattt tggaactggt
    16921 cactcaactg caaggaacaa tccacttgat caaagggaac catgacagtc gcgctttttt
    16981 ccgttattta gaaaaaaatg atcctaggct tactgacgga agtcccaaat tttattttta
    17041 tgatgtaggt gccatcgtta aattcgacca tcaacaatat tacttgactc attatccgat
    17101 gttgctcggg cctaacgaca ctatccgcaa tcttcatgga catatccatc attacagcgt
    17161 acctatcgag aacgatgtca atgtaggcgt agacgcaccg gaaagagaac tcttaaagga
    17221 aaaactacca tttggcactc cgttatctga gcaacaaatc aaagaaatct atgaagcaaa
    17281 gaggaagtac gataggtcgt gaaaaaactg ccctatatca agtattaaac aaataaagat
    17341 aattactcat atttttcatt tgagtaggct tattgccaca ggaacattag gatcagaaat
    17401 ggagttgtaa caagacttct gtcacaactc cattccatac tattcgtctt tttgctcatg
    17461 gtgttctttt accagttttt tctgtaattc tttatcataa tttcgggcag ctgacgttaa
    17521 aaataaaacg attccgcata ataaaatccc gattccggaa aacaagaaca ttttttctac
    17581 ccctaaacga tcagctaatg gtcctgcaaa taataatcca attggacctg ccaggttcat
    17641 caaagagttg aagttcccta agacacgacc taaaacattc gattcataac tctgctggat
    17701 cattgccatc agcagtgtat tgaaatatgg cgttgcacaa cctgctcctg cattcaagat
    17761 aagaaagtac aagaaccctt gactatcgtt tggaaccaat ccgcttgcac cgatcgtcag
    17821 gcccataatg atgtaggcta taataatagg tttcattcgg tctttccatg ttcctataaa
    17881 actgatcagt gcaccgccta agagcattcc gactgcgtag actacttcca ctgctcccgc
    17941 ctgtccaacg gaaccaccaa agtaatctag cgtcatcaat ggatacagac tgattgctgg
    18001 catgaacaac agcatcacaa atgcaccatt gatcgttatg taccataacc ctttattatc
    18061 catcaattgc tgcagcccaa attttgcatc tttaaaaata gtaagcggaa cttccaatat
    18121 ttcaggagaa acttttggga tcttcacaaa aatcaataag ccgacaccaa aaactgcccc
    18181 caatacatct aataaaataa ggtaattgac aggaacgact gaaaacaaag ccgcacctag
    18241 agctggcgca atgatgaaat tcgctgattg gaccattcct aactgtccat tcgtccttgt
    18301 tatgtgagaa gatggaacga ttgtcggcat aatcgactgg atcgttggca tttggaatgt
    18361 ttgtgcgacc gaacgcataa acaaagacac aaaaactagc caaatcggga aggattctga
    18421 aatcgttccg actactgcta aaataagcgc gaaaatcgct acaataatat ccgtgacaat
    18481 caaaagagct tttttatccc agcgatccac tagcggtcct acaaatgggc ttagtaaaac
    18541 catgggaatc attcctagta aagtagcaaa actcaaaatt gtcgccgaac cggtttctct
    18601 tgtcaaatac cagatgatcg catattggac gaccatacta gtgattcctg acaaaaactg
    18661 tcccgataaa aagaacaaat aatttctctt ccaattcgtt aaaacgaccg actgttcatt
    18721 ttccataaac atccctcttt tctttttcat tttgtatagc gtttgcacaa caatcattat
    18781 acgggattct tttttcaaaa aatacctttt tccctaaata acaatcgttt caatttaaat
    18841 ttctttactt agaaacaata aatcagcaaa atattaaaaa taacaacatg tgttaaattt
    18901 aaaaataaaa aagacaacta atttgcgtcg tccttacaaa gttagtcatc taacaatagg
    18961 ccgtttcaaa actagttgtc tttttatatc cacagatcat tcgacttttt cgaataaccc
    19021 acggctaatc atcccatcca tcagaaaata aaatttatct tggctcattt tctgttttgg
    19081 atctttgaaa atattgactg ctttcaatcc atttgctgta gtgatcgaca ttttcaatgt
    19141 ttgaatatct tttgatacag tgatttttaa tttgaatcct tctttgcttt gcggcgtggc
    19201 atctaatggt cggatcaatt gataattgcc tccgtttgtt tctgtaaatc cattatcgcg
    19261 caatgtatat ctttttgcat caggatgcaa acgatagcta attggtgcgc ccagtaccgt
    19321 tgctgttgtt tcaaatgcca tgattttcac ctcgataaaa ttagtttctc tttattataa
    19381 aagtttatcc tgatttttac taggtttttc agttaagttc cctaaaaaat gaaggcgttc
    19441 tctcagacat ctgttcatat aagaatgact tcactagtta ttttttgaca gcacgaacta
    19501 attgatcaag gaaatactgg atgtcgtctt cggtatttcc caaaccaaag ctgatacgga
    19561 tggattcttt tagtatcggt gtatcttctc catacattgc ttctaatacg tgtgaaggct
    19621 cgatatttcc tgctgtacaa gctgaaccag tagaaatagc gaccccatta agatcaagct
    19681 tcatcagtag caaatcattt gcttcgccaa ttaagcgaag attcaacaca tgagggagtt
    19741 tattcgttaa atcaccattt acttgataag ggatttcgtt tgcttctaat gtatcaagaa
    19801 tcaattgctg gaatccttta tatttgttgt tacgtgcttc acgttcttca ggtgacagca
    19861 gttcaactgc ttttgccata ccccagatcc ctgctaaatt ttctgtacct gcacgccgct
    19921 tttcttcctg ctccccgcct aaaagcaatg cagggatatt tactccgtct cgtttatata
    19981 agaaaccgac gccttttggc ccattgattt tatgagcaga gatacttaat aaatcgattc
    20041 ctaattcttc tggatggatc gtttggtttc cgtacgcttg taccgcatct gtatggaaat
    20101 aagctggatg atccgctaaa agttcaccga tttctttgat tggcatcaaa tttccgattt
    20161 cattgttccc gtacatcaca gagaccaaga tcgtatcttc tcgtaacgct tttttgacct
    20221 cttcgatcga cagattccct ttttcatcta caggcagata tgtaacgtca aacccctttg
    20281 tctctaaata tttcatggta ttaagaacag caggatgttc gatagctgta gtgattagat
    20341 gtctgccttc tttttgacgc gagaacgctg tttctaagat agctgtatta tccccttctg
    20401 ttcccccact gttaaagatg atctcgtgag gttttgcttg cagactgtct gcaatgattt
    20461 gtcttgctgt ttccaatttt tcatgcgcgt ggcgaccaaa tccatgtatg cttgaaggat
    20521 ttccaaacgt gtcttgcatg attgccgtca tcgcttcaat tacttgtgga tgcatggggg
    20581 tagttgccgc atgatccaga taaatagttt tcacttcatt catcccttcc aaattattgc
    20641 taggcacatt ctagcataaa atagcgaaca aaccaaagaa gagctcattt ttgtctagag
    20701 gacgtttcat gggcatagaa aaaaggagct gtgacaaaag tcttgtcgca gctccttgaa
    20761 gctgctcact tctgtcacaa cttctttccc tctttttttt gtttattcga attctttttc
    20821 ttccagacgg aataacggac tcatcggtgt attttcatgg atgcgtttga ccgcttcacc
    20881 cattaattct gaacatgtaa cgattgttaa gttttctgga tgacgatttt cttctgtgaa
    20941 aacagaatca gtgatacaaa tatctttgat tggtgcattg tctaaaatac ttttcgcatg
    21001 atcggacaat aatccatgtg acgcacaggc atatacttct tttgcgccgt tttcttttaa
    21061 tacatttgct gctcgtgcaa gcgttgctcc tgtgttcaag atatcatcta ccatgataca
    21121 tgtctttcct tgaacatcac cgatcacata accaccctca gttgaagcat catctgcatg
    21181 atctacgatg gctaatgtgc tgttcaaata ttctgaaaga ctacgtgcac gctgaacacc
    21241 gctgtttttt ggcgaaacaa ctacgatgtc atctcccgtc agacctaatt gacggtaata
    21301 atgagcaaac aacggcatcg taaataaatt atctacagga atatcaaaga atccttgtac
    21361 ttgaaccgtg tgcagatcta aagtcagtac tcgagttgcc cctgcttctt cgatcaagtt
    21421 agcgatcaat ttcgcagtga tcggttcatg aggtttcgcc gtgcggtctt gcctagcata
    21481 cccatagtaa ggcaatacga cattgatcgt tttcgcactt gctcgcttca ttgcatcgat
    21541 catgatcagt agttccatat agtaatcatt gacaggtgca ttcgttgatt gaacgatata
    21601 cacatgatcc cctcgaatac tttcttcgat attgatggaa atctcgccat cactaaattg
    21661 cttcacgacg cttttaccta attctgttcc gaacactttc gcgatttttt cagctaatgg
    21721 acggttgcca ttcaaactaa aaatcttcaa cgtgtcatcc tgatacttat tactcatgta
    21781 gtcctcccca aaacttctct attcttcgat agtttaacat atttttccaa gattttctgt
    21841 taatttcagc aaattcttaa ggaagtgaaa ctgttccgtt actccaactg gcaggaatga
    21901 ctttatgata atcgccccag ttgtcgtgta ctttgtaata acgttctcct gtttcagttt
    21961 caaaataagc gtacgctgtc acccaatgat tgccatatgt actgccaagt actttcaaaa
    22021 taccaatcat cacaggtttg ccttcacgta tacgttttgt agctcgctgc catgaaccta
    22081 gaagagttgc tcgtgcacgc tcatgattgc cattcttctt taaaaaacta gaaatccctg
    22141 tactaacctg aaaaggaatc gtaggaagtc ctagtggttg gatctggcta cgcaatgcct
    22201 tcgtcaaaac caacgaatca gccgtatttt tcttgcgaat ctcatttgga agcatccacc
    22261 ccttacgata gtcttgataa taggcaagga gaactgctgc cgcgtaagta ccacaaagat
    22321 agcctgaggg ggtagcccat ttcttatacc tcaaaaaacg ttcttctggc aatcccaccc
    22381 agcaatttgc gagttccttt cctgaccttt tttcttcgat caaaacggga atatcttctt
    22441 ttctgttgat ccatctagat aactcgattg gctcttcatt gatcagcttc cattttttac
    22501 aagaaagacc ctcttgataa gtatattttg ctggagaata ttctaccgga tgtcctgatt
    22561 gatcgataat cacataactt tgatcttcaa aaaccagagc taaaaaaagc aatttacttt
    22621 ttcttgactg cagctgctga gtgctggcta attttttaat ttttttatct actttgaaat
    22681 ataaaggttt atccactact tgattcagtt gggatcgcct cctttttttc attataagtg
    22741 aaggattgaa aaaaacaaat cagtttgatt gttcgaattt tcaatttttt atgttctatt
    22801 tgttaattcc ttcattttgt aagataatgg gcacacgaaa caaaaaagga gcgatcgatg
    22861 aatgaacaaa gaacgattga aacaagattt ctatgaagca gtcaatgaag aatggcaaaa
    22921 aacagcaaaa atccctgcag ataaaccagc tacaggcggt ttccaagatt tagttgacgg
    22981 gatcgaccaa cttttgatgg gagaaacaga cgatctgctt gcccatccag aaaaagtgtc
    23041 ttcagaaaaa atgaaacatt tccttgcata ttatcaactg gcaaacgatt atgaccgaag
    23101 aaatgagttg catgctcaac cgcttcaacc tataatcgaa aaagttgaat cattgcagtc
    23161 tttcgacgaa ttgaataagc aatttccaga atggctgttg gatacattac cattgccatt
    23221 taatctggat gtagatgcag atatgaagaa tgcgcaaacg aacgccttct ttgcttatcc
    23281 gccttcttta ttccttccag ataagacgta ttatgcatca gaccatccca acggtgcaca
    23341 actaataggc gttttctttg atatggctgt tcagttatta gagcttgccg gcaaagaaaa
    23401 aagtcaggca gaagcaatca cggaacaagc agtgcaattt gataaattga ttgctcctca
    23461 tgtaaaaagt gcagaagaaa acgcagatta cagcaaaatg tataatccgc aatcttttga
    23521 tacatttatt aaatacacag ataaactgga cttgaaaaaa cttgtcacgg gtttgattgg
    23581 gacaactcca gataaagtga tcgtaactga tccagtgtac ttcgatcatt tgaatgacat
    23641 cctgacagaa gctcattttc cgttattcaa aagctggatg atcattaaaa cagtacgttc
    23701 tcttagtggt tatctatcag aagaattccg ccaagtcagc ggaatctatt ctcgcgtatt
    23761 gtctggaaca gacgaagcaa tgcctcagaa aaaagcagcg tattaccttg cctctggaca
    23821 attcgatcaa gtagttggcg attactacgg aaaaaaatat tttggcgaag ctgctaaaaa
    23881 agacgtagaa caaatggtga aaaaaatgat cgccgtttat aaaaaacgtc tagaagaaaa
    23941 tgactggctt ggggatgcaa caaaagaaaa agccgtcata aaattaaata acttaggtat
    24001 ccaagtaggc taccccgata agatcccagc attattcgac cagttcaaaa cagtacctgc
    24061 agatcagggt ggtactttgc tttcaaatac tcttgttttc agcaaactca cattaaaaga
    24121 tcgtttcagc aaatggaaca aaccagtgga tcgttcagaa tgggaaatga gtgctgacac
    24181 ggtcaatgct tattatcatc catttcggaa tgtgatcgtc tttccggcag cgatccttca
    24241 agcaccattt tacagtctag aacaatcaag ctctgctaat tatggtggaa tcggagctgt
    24301 tatcgctcat gagatttccc atgcatttga taataacggc gctttatttg acgaatatgg
    24361 caacttgaac aactggtgga cagaagaaga tcttacacaa tttcaaaaca aagcacaagc
    24421 aatgatcgaa gaattcgatg gtctgccttt tgctgacgga aaagtaaacg gaaaattaac
    24481 cgtttcggaa aatattgctg atgcaggcgg tctaagctgt gcattggaag cagcaaaaac
    24541 ggaatcagat ctttctatcg aggaattctt tgtcaattgg gcaacgattt ggcgtacaaa
    24601 agcaaaaaaa gaataccaac aacttttact gcaaatcgat gtccatgccc ctgctaaact
    24661 ccgagcaaac gtgcaaccaa aaaaccttga cgaattctat gaaacatttg gtatcacgga
    24721 acaagacgct atgtatctag cgccagaaaa aagagtgcga atctggtaag aggttgtgcc
    24781 agaagtggtc agcttcaaga aataagaagg aatttgggaa aatcgcttct caaatttttg
    24841 tgacatttcg gcttattttt cgaagaagtt acttctggaa taccatgtat tagaggttgt
    24901 gaaaaagctg cttagtttca agtagtaaga aaaattttgt gaaaatggct ttccacattt
    24961 ttgcataaat ttgacttact accgagaaac tggcttttga acaccgttta tcgagaggtt
    25021 gtgaaatcag cgtcctgacc tgagtattag agaaaaaaac ggaaaaatag ttcctcatat
    25081 tttgccgttt gttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaga
    25141 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aatcaaaagc agcaaggaga
    25201 acctcatcta taaaaagata gaaggaagtg agacatctat tggtctcatt tccttctatt
    25261 tttactttcc tcagtcaatt gttttacatc ataaaaggag aaattccact tatttttttc
    25321 gctgtttcat gacataaaca actacaccga ttaacaaaat tcctccagct aatgctagca
    25381 acgggttatt aaattctccc gtttttggga gtccttgagt gccatttttt tcactttctt
    25441 ttgctgtcct atccggatga gaaggttttc catttggttt tccatttggt gattcatttc
    25501 ctggattttc tctttctggt ttgtcatttc ccgggggcac atcggcagtt tctcgcacag
    25561 tgatcgcttt ttgctgggta acagattctg tatgagcaga ccatttttcc ccatcaaata
    25621 tttccgaacg ataagtgact tctagcgtat attctccttt tgaaggtgct gaaaaaatag
    25681 cggtatgatt agaaaattga gcacttgact gtgtttcaac gatttggatc ttttctggga
    25741 aataacgcat atcttcaaag acaggcgttc cttgatttgg tgtgaaagtt gacacaaaaa
    25801 ctgtaaaagg cttcagttca atgatatttc cttctgcatt ctccgccaca ccatttgctt
    25861 cttgtataat aatcggatta ttttgttcat ttggttttgt ctgatttggt tcttgtacga
    25921 ttgcatactc tggatattcc gaagacggtg aggtttctcc gtcaaaaata gcacctacag
    25981 ataatggaag accatccact ctttcctttt ctgtttgacg attccccggt ttaatctgca
    26041 tcagtccatg aacatggata cttccatttt catagcgcgt aacaggctgc tgaccttctt
    26101 tcgaacatgt atttagagac tcgatccaat cttttgatat ggtatgtcca agagtatttt
    26161 ctgattgttt ctctcgttca ttccaatagt agttcaacga gtggtagatt tgatcttcgt
    26221 tttgattcaa tgggcggatc tgctctctca tctcaagatt ctctgttcgg aaagataaga
    26281 taccagaagc atggtagtct gtgtttcctg ctgaagaggt ataaagagcc acattatatg
    26341 aaccgttatt aaaacttgta ctgctattga cgataatatc tgttccgcta ttggaatcga
    26401 ttcctttcgc aagattttcg aaagacaaac tattgatcaa ttcatgaggg cccgttaaag
    26461 aagaaccgcc cattttgaat ccattaccgt taccttctcc ctcaattcct ggtacccagc
    26521 cgtttcgata agcaactgag tttttgatga ttacttttcc gatcgaacct gtttcatttt
    26581 tagcaaaaag gtcccaaccg tcatctgcat tatgatacgc gatacaaccg tcaaatacat
    26641 ttccttctcc tattgtcagt ttggccgcaa atccatcggc atcttcaaat cctggatcgg
    26701 cattttcaaa agatgtacag ttcttgacta agttatgcgc gggccatgct tcgaaaggat
    26761 catttgagct accgctgatt tggattcctg tatttccatt ccgataagca tgaatctctt
    26821 cgatcaaatt atgatttcca gaaatctgta atcctttttg catagctgca ctatttgtaa
    26881 tgtcaaaccc tcgtaaaccc cagtagtgac tgaacagtgt catcccattt ccagttcctt
    26941 taaaatcaag tacaggacgc ttgttttctg gatttttctc tgcaatcaac tgaatcgggt
    27001 tttctcttgt cccgttaacg ccttttggaa tcgtcaatcc tctttcgaag gaataagttc
    27061 caggcgccat gacgattgtc tgcccagcat atgcgtatct caatgcttgt gtcagagata
    27121 atggattttg tctgcttccg tttcctgcat ctgacccttc tggtgttaca taaactgtcg
    27181 aatatttagg tttacggtag tccactgtat gaagaatctc ttttgtttca taactagtca
    27241 tctctacgta ttcttctggc ggatagtttt tatctggcgt aaaactgaaa gtaaattcgt
    27301 tcgttccttc catcagtttt gtctgataat caaattcccg attcgcagtg atagccaagt
    27361 tttttgcgtt cttaagcacc tctcctgttg ctttattttt aattgtcaat aatccgtcag
    27421 catttgctct aaaggacata gtatgatctt ggtttcctga atgattacta gaggtcacag
    27481 tgtaaatcgg atcaatcaag cgagtaggtc tttcttgccc aggaggatct gtcgcaggat
    27541 ctgagtaagc aacttcgatt ccttctacct tgatcgtcat attccttgct gcagcaaatc
    27601 ctgcataaat aaccgattca tctgaagcgt ataatttttc ccagtcatac atgatgtcag
    27661 aagccatttc ttctcctgtt tcaggatcgt aataatatgc ctctaaacca gtattcgttt
    27721 ttttcatctc tacgtccagt ttagtaatcg agttcgtggc cggaaacaga ttcccatgac
    27781 cgtttccgaa tatattataa gaacctgttt ctttttccaa gaaccctgct gaagtctcta
    27841 aaggtgttgt ttccactgag acactcccag gagctggcgc agcttgcgga tcttcagatg
    27901 atattcctgt gattgcccgt gtccccaatc caagtcgcat cgtatatttg ctgccgctcg
    27961 tgttgaccac ttcttgtcta tccgagtccc agacatattc gatccgactg cctagtatgg
    28021 caaatgaatt tgaataaaat gcctgcccaa acaaatgatt ttttggtact gcgtctctta
    28081 ccattaaagc aaatccttct tgggcattcg tataggtcca agattctatt tcgatcgtcg
    28141 cccgcatcct aaagttgatg tctttgggga ttgcttgata ataataggtc attccatctg
    28201 atccgcttga ctggaatttt ccgccgttat tcgtggaaga gagccgcacg ccgtcttcta
    28261 atggttcaat ggcataccta ctagcacttg tgctttctcc gaaaacaacc cctttccact
    28321 cttcatttgc ttcttcagat tgcttttttg tcttttcatt ttctgattct ttcatcatag
    28381 gatcatttcc ttcttccgta tccatatctt cactagttct tggtatttcc tccattgttg
    28441 acatcccttc aatgttcacg tgtgcatttt cttcgttcac agactgttgt tcgttagcag
    28501 caacttcaac gacagaaatt aaaaccgggg tactgagcat aaggagattc atcattagcg
    28561 cactgtattt tatacgtttt tttaacaagt gtattcctcc cgtaacaaat tagaaagcgt
    28621 ttacttaaag tattacctaa tttattttta ctgtcaataa aaaacaaaat tataataagt
    28681 gtattttata aaaagaaaaa atataactta agttgttgat aataaagaga tttattaacg
    28741 taaaaagaat aagttttttt aaaataacgt ataaaaaaga gcataaaaca aagtcgtttg
    28801 ttttatgctc ttcttttatt attttgtgct ttttatttta tcaaatcact ttgttttttt
    28861 ataaaatttc tgcgcctagt gtggactcaa aatgtctcaa tgcccattca tgtccaacgg
    28921 gatcgaaact tgccacggca tctttgaaaa tatggagttt gtatcctaga ttatacgcat
    28981 cgactgctgt atgcaacaca cagatatctg tacatacgcc ggtcaaataa atatctgtga
    29041 tctggcgttc tcgcaaacgg atgtctagat ctgttccact aaaagcggaa taatgccgtt
    29101 tgtctatcca ataaacattt tcctcttgct catagtcttg gtataaactt tttaaagagc
    29161 cgtacaattc ccgtccaccc gttcctatca cattatgcgg aggaaataag cggttctccg
    29221 gatgaaagga atcttttgga tcatgcgcat caatggcaaa aacgacaaaa tccttttgat
    29281 caataaactt ctttgtatga gcagtcagct ttttttcaat tacttgtcct gctgtcccag
    29341 tagtcagctt tccatcctct gcaacaaaat catatgtgta gtcaatcgag atcaatgcgt
    29401 tcatcttagt cctccttata cgagatgttt gacaaattcg atcaccattt ctgctgatcg
    29461 tttgcctgcg tcttcgataa attcgtcaaa gctttgtgtc gccgagtgat ctgctgtgtc
    29521 gctcattgca cgtacgatca aaaatgggat attgaactga cgagctgttt gtccaacagc
    29581 ggctccttcc atttcgcaag ctaatgcttc agggaaattc gttaagattt ctttgatttt
    29641 atctggcgag tcgacaaatg tatcacctgt aacgatcaat ccttcttttg cgttcaaatt
    29701 cgttgctttt gctgctttaa ccatttcact gcgcaaatat gtgcttgctt cataatatag
    29761 aggcattcct ggtaattgtc ctgggttgta gccaaatcct gttgcatctg catcaaaata
    29821 agctactttg tctgatataa cgatgtcacc tacttgtaag ccttcaccga ttccgccagc
    29881 tgaacctgta ttgatcacca tgttcacgcc gtattgttgg atcaacagac ttgtggtaat
    29941 agatgctaag acttttccta taccggaacg tacgacgatc acttcgtggt tacctaatga
    30001 acctgaaata aataaagcgc ctgcgcgttc ccatgataat ggttcgctta ggttctctct
    30061 caaaattttt acttcttctt ccattgcgcc gataataccg attttcatct ttttaattcc
    30121 ttctttctat ataaatgcga ttgctaaaaa aaccacacat aacattagga taacaataat
    30181 aagagatttc atcaaaaaag agttccattt ggtcgtcttt tcccgttcgc tgatccttgt
    30241 tttcgtgatt ggtttattct ttttgctttc tttacgataa aagctggcaa tctttttttc
    30301 ttcttgctga taagctgttt ctgcttttcg ctgttttttt aatgactcgc ttgcttgtgc
    30361 ttgttgtcgc ttgcgaagtt cgcttcgcgt aataagcggt cctttggcca taagccgatc
    30421 cctctacttt cctttggtca atagttccca gtattgaatc gcataaatcg tctttgcatc
    30481 acaaatcaac tgatctttca tcgcttgttg cgcctcttca agagttagat gatacaactc
    30541 cagtacttcg tcttcatctt gtgctaaagg attctcgacc ttctctaccc cttgtgcatg
    30601 ataaatatga aggacttcat ttgcaaaacc tggtgaaaga tacatcgaag taagatggct
    30661 cagcgacttc gcacgatagc cagtttcttc ttctaattct ctagctgctg tcatttcggg
    30721 attttgtcct tctcctggat cgatttttcc agctggaatc tccaaaatca ctttttctaa
    30781 aggttttcga aattgtttga caagaagcag acgatcttgt tcgtcaaaag caatgatccc
    30841 gacaccgcca ggatgaaata ccagttctct cttcgaagtt cctccatctg gcaaacgaac
    30901 ttcgtctaca gcaacatcaa taatttttcc gctatagatt tctttgcgac tgattgtttt
    30961 ttcttcaaat tgctcattgt tcagcatatc ttctcctgct ttctttgtaa tcataactgc
    31021 ttttttttca tttttcaatt tttctcaaaa actccttatt agtttaccat agataaacct
    31081 tagattttct ctaaatatag aaaatccttc tttagtccga tactctttat agtagtccgt
    31141 atgctaaaat aagtatgtaa tcgaataacg aaaagaattc aatactcaac gataaatgac
    31201 atggagggtt tattatgata aaacgaaatt ggccgtggct tctagcattg gtcttgctat
    31261 ttctctttgt ccgaaacaat agtttttctt ttgttctagg acttttattg ataggtgtag
    31321 ttttagtttt gtggggactc tttggttcgc gcaggaaaaa gggaaaacaa gaagaaattc
    31381 ctgcactgac tgacgaactt gaaactcact atgaaaaaag cggtatgaca gcgaatgaaa
    31441 tttcattttt tcgacaaaca atgaatcaaa caaaaaatga gatcaatcaa ttgcaaatga
    31501 atatgcagca gacagccaaa cttaaagcaa tcgatctccg ccatgatcca gtcaaagcag
    31561 cgaaagcttt attcaaagaa ttggtgaaag aaccaaaccg actgcatgaa gcaagtcagt
    31621 ttctttatac gcatctgccg aatctagttg atttgacaaa taagtataat gagatcaatg
    31681 accatgagat caaaaacaaa cagacctatg aaaaactaga agaaagcgcg cagatcatcg
    31741 accagctgtc agctttaatc gcacaagatt atcaaaaatt cgttgctgag gatctagatg
    31801 atatcgacgt agagatatct gttgcgaaac agagcttaaa gcgtgataat aaatatgaac
    31861 cagaacaaaa ggattaactc ttttgttcat aaaagaagac tcggaacatt cagatgatgt
    31921 ctggctgttt cgagtacttt ttctaaagta gagacattca tgtaagaatc gagaacagat
    31981 tcaacaagga ggaatttttt atggatcata aaccgactga aacaaaagat gttacaccag
    32041 ttaacgatac acttgaagat ttattgaaca acccgttttc aactccaaca gatacgctga
    32101 ccacttcaca acaagcggag attgatcagc tccaagagca acagacagct gctcgtttaa
    32161 ttgacaaact accggcggaa cgccaagaac aagctaaaca gctagcagca aaaatcgatg
    32221 ctaatgatgc acagtctgtc atcagctacg gatcggctgc ccaagcaaaa ttaagtgaat
    32281 tctcacaatc gatgttgaat catgtgcaag cacaagatat tggtcctgta ggagattcct
    32341 taactgaact gatgtatcgt ctccaagaag ccaatcctga cgaactgcgt gccggagaag
    32401 ggaacatctt ccagcgtgtc ttcgggaagg tcaaacaatc gatctatgaa gtgacagcaa
    32461 aatatcaaaa gattggtgca caaattgaca agatttcagt gaaattagat aaagaaaaag
    32521 acggtctgct aaaagataat ctgatgttag aacagcttta ccagaaaaac aaagactact
    32581 ttgatgcact gaatatttat atcgctgctg gagaattgaa aatggaagaa cttcaaacaa
    32641 cgatcattcc agaagcgatg aaaagagcag aagaaactgg cgatcagatg gatgttcaga
    32701 ttgccaatga ttacacgcaa ttcctagatc gtctggataa acgtacgcat gatcttcgct
    32761 tagctagaca gatcacgatc cagcaagcac cacaaatccg tttgatccaa aacacaaatc
    32821 aggccttggc tgaaaagatc caagcatcta tcgctacagc cattccgctg tggaaaaacc
    32881 aagtcgtgat cgcattgacc ttgcttcgtc aaaaagatgc agtaactgct caacgccaag
    32941 tctctgaaac aacaaacgac ttattgaaga aaaattcaga aatgctgaaa atctcagcca
    33001 tcgaaacagc gaaagaaaat gaacgtggaa tcgtggatat cgagaccctt caaaccactc
    33061 aaaatgattt gatcgaaaca atccaagaga cattgcgtat ccaaaaagaa ggaaaagaaa
    33121 aacgtcgtca tgcagaagta gagcttggac acatggaaga agatctgaaa caaaaactgt
    33181 tggatttaac ccaatagatc acctttcgct tgttactaaa acaaacgccc aacaacagtt
    33241 tattacaact gttgatgggc gtttttctta tctttcttct aacttctcca ttggagtcta
    33301 tttctcattc atcttgctgt gtccatagcc atagccaaaa taaatgatca gtccaataac
    33361 cattacgata ccgaacacga tccatgtcac agtttgcaga cgaagcatca atacaataca
    33421 agtcaagatg gagacgattg gcaatagcgg aacgaatggc actttgaatt ctccagcttt
    33481 tggtttgcca aacatttttc tcaacttcag taagcctaga ctaacaagca tcaaataggc
    33541 gagcgccatg atattcgtta gttccgctaa tacattcaat gggaaaaatc cggcaaagaa
    33601 tacagctgcc acaccagcgg cataagtcgc ttttttcggt gtacgatgct tttgatcgat
    33661 ttctgtcata aacttaggaa gtaagccatc cttgctgaca gcaaacagta aacgagcaag
    33721 tgaatacatc atcgagatcg ttaccgtcag tagcgttaaa attgccccta cagcgatcac
    33781 cgcgcccact gttccatgtc ctacatacct cattgcaaaa gccactgggt cattgactcc
    33841 tagttcagta tacggaacga ttcctgtcaa gatcagcgtc acgatgatgt aaaggacagt
    33901 agcaatcagt atcgaaccaa tgattcctct tggcacatct ttttgcgggt ttttgacttc
    33961 ctcggctgcc attgcaacgg catcaaatcc caagaaagca aaaaacacaa gagctgcacc
    34021 atctagcaca ccggaaaaac caaaaggcat gaatggctgc cagttatcag gtttaacgaa
    34081 aaatattcct acaatgataa acaacgcgat gataccaaat ttgacatata ccatggcatt
    34141 attcaaacgt aatgctttct tggcttcaag cgacacgatg taagtgacga atatcactac
    34201 gagcaccgca atcaagtcaa tgtatgtacc attttccgga ttgtacccgc cagttaatgc
    34261 ttgtggaagt tcggccccta aacttttcaa aaaaccttgc atatagccag accatccgga
    34321 agcaacagag gaaaccgcta gtaaaaattc cccgatcaac aaccaccctg tcagccaggc
    34381 agcaaattca ccaaatacaa catacagata ggcatatggc ccaccaatca ctggcactcg
    34441 cgaagcaaat tctgcgaaac ttagtccaga caaaatgaca acgattgcag ctaagacaaa
    34501 tgaaagtgac agtgctggac cagcattttg attggccgca acccctgtca ccacaaatat
    34561 tcccgtaccg atgatcgcac caattccaag catgatcaaa tcagacgttt ttagttcttt
    34621 tttcatctca ctcgtatgat tgagattgat ctctttctta cgaaacaaat ccattgaagt
    34681 tcctccccat tttaggttgg aaaacagcga ttaaactgtt ttcatatacc ctaaaaggat
    34741 accacctaaa atgactaaaa ggcaaccaac aataacataa atgagctctt ttttcgtttt
    34801 tctttcgcca aggatgaaaa tcccacctaa agtagagata atgatcccca tttgtgaaag
    34861 tgagaagcca acagctaaac caagtgattt gactgttaga agcatgcaga tgtttcctaa
    34921 gccccataat aatccacaga tcatgttttt ccacacaaac tgatcgactt taactttacg
    34981 gaaagcaaag aagcttgcgc ctaagatcat tccgatactt tgaggtaaga taattgacat
    35041 cgcatccaaa ttcgcccagt tgacgatgat ggtatataca ccataaccaa tcgtagagaa
    35101 gatcaatgct ctaaaaccct taccaaaatc aagcatttta ttatctgtat ctatttttcc
    35161 ttcgtcatct tgtcgggcag tcaaatacgc accgcttaca agaagagcta aagcaataat
    35221 accgtataca taatctttcg tttgtgtcca ttcatggaag aaaacggctc ccgcaatcgt
    35281 attcaaaatt aattgaaaac cagtagacaa tggtagccct acagaaacac ccatgtactt
    35341 cattccatgg aactgtccat tttgtccaac actccaagct aagccggata aaaatccgat
    35401 caagaaaatc caaggggtga ttacaggact aacaacgaaa aagacaacta aagaaaacag
    35461 aaatgcaccg atcgtcattc ctagtgtttg ttgattggca tcgccaccaa ttttaccact
    35521 tactaaacca atactacccc atgccaacat agggactaat gctattaaaa tttccataac
    35581 caatctcctt ttatttcaca tgataagaaa cttatcagcg aaaacgttaa caacacaagc
    35641 actttttttc gtttctaacg attttctaac gtttttcatt ataaaaattt aagattggga
    35701 aaaataaagt cattgttgtc ccttttcctt cagttgattc agccgtcaaa tggataccta
    35761 atttttcggc cagatttttt gctaaataaa gtcctaatcc tgttgaatgt gttttgctaa
    35821 gtcgaccatt tctcccagta aatcccttat caaagatccg tttcaagtct tccgctggga
    35881 taccgatccc tgaatcttta actgaaaggc tgactccttg cgcttccttt tctatgctca
    35941 caatgatgtt tccgtgatcc ggcgtatatt tgatggcatt actaagcaat tggttgaaga
    36001 taaaagcgat ccatttagca tcggtcaaaa cagtatgatc ctcaccaacg atctcgtagc
    36061 gaatattttt ttggataaaa taatttgcct gactgcgtat cacaggctga atgattcctt
    36121 ttagtccata ttcttggatg aggtagtccc gcgagaaact gtcgagtctt gcataataca
    36181 aaacttgttc tacgtattca tcgatttttg ataattcatt ttctagtaat gtatactttt
    36241 gatcgtcaat atcgaactcg atcgaacgaa ctagcaattt agaagcggaa agtggcactt
    36301 tgatttcatg gacccatgag tcaatataat ctttttggtc ttgttgatta ctgattgctg
    36361 attgcattac ttcttggtgt tcacggatca gctgattgat atattcttct accagttttt
    36421 cttcttctgt cctcccacca ctcaaataat tttgcaaagg ggaagttttt tgtatgtcgg
    36481 ctaattttcc ccaccatctt ctcttgctca agtaaccacc cagcagataa aaaatcagaa
    36541 agacgccctc aatcaaagct aaataagcaa ttgtgctcaa atcaactttg atgtttggcg
    36601 ccagccacat cacaaagatc gtcaatgcaa taaaaaacag ccatcccaag atcaatgtcc
    36661 actgatcttt caaatattta aaaaaattca tcttaaccgc tcatcctttc agggaacgat
    36721 atatccctgt cctacttttg tttcgatata tccttggata cctgcctgtt cgatttttcg
    36781 gcgtaaccga ttgatgttga ctgtcaatgt attgtcatct acaaatcgtt cgtcatccca
    36841 cagtgctcgc agcaattttt cccgacttaa gatctttcca ttgtgcttca tcaaaataaa
    36901 taatagacga tattcatttt tgctcaaatc aatgatctct ccgttgattt ccatacttcc
    36961 gttgtcaaca ttcaacgtaa tgccattgtg gctcatcatt tcactagata attctgtgta
    37021 gttgtaagaa cggcgaagta atgcattgat ttttgcaatc agtacatcga tttggaaatg
    37081 ttttgtcaca aaatcatctg cccccatgtt catagccatg atcatatcca tattcgtatt
    37141 cctgctggag ataaaaatga tcggtacttt cgatacttca cgtatttttt gacaccaata
    37201 atagccatcc aaaacgggaa gattaatatc tagtaataca agctgtggtt cttctctttc
    37261 aaagtctgag aacacttgat tgaaatcggt cgttccaaag gtttcaaatt gccatttctc
    37321 aagttcctcc atgatcaatt gtcgaatgat ctcttcgtct tcgactacca tgatttttgc
    37381 cataaaaaat ccctccatct ttcttcttgc tactacaata tcaaagaagc ccttgtgaaa
    37441 caagttggct tacctggaaa atgtcatttt agcaaacgtt aaaaaaaact ggaaatatgc
    37501 gatttaatcg cgtttgtctc ttccaagcag cttaaattta ttatgttatt cttaataatt
    37561 ggtctattat ctgttatttt tctttcgttg tttttgtctt ttaaattttc gataacacca
    37621 ataaccgaaa agcgttagca ctagcaatat acctagaagg agtataagta atcgataaag
    37681 atggtatttt tttgtctgtt ctatctttga agagacttct tctgtaaagg gaactcgtct
    37741 tcctgtcact agtaatcggt gagtgttcac ggtgtaaggt gtacaagtga taagtgtgac
    37801 tagatcctgc ttttctctaa ttgctaatgt atttgttttt gttggaagga caacaatttt
    37861 ctcaacgact tcataagcga gcatccgacc atacacttca agatagaatc ggtcatcttg
    37921 ctccatttct tcaagatccg taaagagttt tttctcagca ataccgctat gggcggtaat
    37981 cacggaatgt gtactctctc ctccagttgg aaaagaggtg ccttgcagga ctgtcgctcc
    38041 tctatctaac aaaagatcat tcgtttcatc aaataaaggc aagctaacat tgattttcgg
    38101 aatatagatg gctccgatca tatgttgttc gtaatattct tttcctggat tttggacatt
    38161 tctaaccgct tgctcaaaag gatctttgac ttgtcccatt cctgggatta ctgatgtatg
    38221 agcaagcgtc tgatttttct tttcatgcac tgctaattgt tgctcatgtt tttcttcttt
    38281 atcgcgttca agctgctttt gataattctc gatccttctt tgatccaaat aattgctgag
    38341 agcatctgct aaaaatggat atgtaaaaac tgcagctccg gcaagaaaca tcactgccat
    38401 aaataattgt aataaaagac tgatttgggt ttgaggtcta ttacctattt tctttttcat
    38461 tttcttcacc ttcttattta aaaaaactgc agcaaccttt ataaaaccga ttgctgcagc
    38521 ttatttttgt tgcttatact tcagacttca ttttagattt acggtaccag ctgtacgctc
    38581 caatcatcaa acttattccg attagtaaga atgccaagag cccgttccca ccagtagcag
    38641 gaagtgaccc gcgtttcata ttcggtactc tttctggccc tggattttct actcctacga
    38701 tctgaatttc ttcattatag cttccataag agatgataaa ttcagtaaag gctgcctcac
    38761 ctgttggaag tacataacct tctggcgcca tggtctcttt catttgatag gttccataat
    38821 ctaacccttg aacctcaaag tatccatttc catctgcgac aaattctgtt gcttgtccgc
    38881 ttgttgccca ctcaattcta tctgctcctg attcataaac agctaaaggc gactcccctt
    38941 tataaaatat tgcgtattca gaacggtctt cattccacaa ttcgaatctt gcatctttaa
    39001 gcaattcact gcttgatgca tcatattttt caaactttct tccacctgtt gtgactttct
    39061 ctggcggctc tactccttct tcataatcaa attcatcatt tcgtccgatt tcaataaccg
    39121 ctgtgttgtt atggaaatca tccgcttcta gttctgtgga aaccttcaaa ttatacgtga
    39181 tcgttaaatc tcctccacgt gcatctgcta atctacctaa agtatctact ttggctactc
    39241 cattttcttc tgtcaaaatc gtcacgacaa acccgttgct tactacttct actatataat
    39301 cttgtccttt tgttaaaatc gtctcgccgg ctcgcacttc tatttcctga tcataataag
    39361 ttagaccaac tgtaggcgta tctgtgattt tgtaattttt gataacagcg cttccgtttt
    39421 caaggacaga atcgatgaaa taaggaatag gtgctgtgat cgtgtaagaa gccgtttttc
    39481 ctctttctag atcaatataa gaaatcgttt cttgttctcc agcttcatta ataatcgtta
    39541 cttgtctaag gtcgctttcc tctacattca tctgtttatc tgcttctctg atttcgtttt
    39601 tcggatacaa atgcacatct gtattgtatg tgtctttcca tgtagaacca tcccacacgc
    39661 catccaccat atcaggcatc atcactggca tcataacaac cattggagac gcgattctgg
    39721 aaatatgagc tggcgaataa gtttctaaga aaagatagac tttatctcta gaagaaggtg
    39781 cttcttccgt cacttggacg gtagagaata ccgcttctcc agcttcattc gttgtttgtt
    39841 tgtcaatact tgtcagtcga tattttaaaa accaactttc tgtgtgccgt ttttgaatcc
    39901 attcaatcgc ttcggcagaa ttaagaccgt cttctcgttc cggtgttaaa ggattatctc
    39961 gaatcaaatc gtaatatact tccgttacgt caaacaaatc aaaatcgact cctggaatat
    40021 tttcttcacc aaaatccgta gaaaccaatc cgctattcgg tcgttcttcc ggaacagatg
    40081 agaaaccttt tttgtgtaat gtaatcgtca cttcacttgg tttttgtgcg acttcttcgg
    40141 ctttgactag ttttccgttc ccgaaaatcc ctattcccgc agtaacgagt aacagtacac
    40201 tcattcccgt gacaatcatt tttttattca tttttttctc cccgttcttt ttttattaat
    40261 aaaacagcac ctaacaataa aagaattcct agtaaagaaa tcaacgttct tgcttcattc
    40321 gtttgcggga atacggacca ttttcctgat tgacctggat tgcttggacc actcggctct
    40381 ttcggtttgt ccgttgtttc ttttacggtc tcgttataaa cacgtggtgt tgcggattca
    40441 taggcagaga ctggaacttt cccggattct aattcagcca tctcctgtcc gttaactact
    40501 acatattgtg gttggccttt tgcatccacc caaaattcag ggatgatgac ctcgattctc
    40561 ttacttgctt catccatctc gtaaccttcc acacctttta attcttcaaa ataataggtg
    40621 ccagaaggca agaaacgttg tcctgtcgta acaaggccct ctttatccga aatgaatttg
    40681 cttacatttt tgtcattcaa aggatcattg tctgctggtt tgatccattg atttttcaag
    40741 tcattagcag gagccatatc taaataatat ttcccccctt ctatcatctg atatagagca
    40801 aaaacagcac cttctaatgg ttttcctttt tcagttgttc ctctttgacg tccatacttg
    40861 aagaagtatg gatctcttag ataaccgaca tttttaggat agatatgaat ctcttgcagt
    40921 tcctcggttg attctgtcgg gtgataaatt ggcaaaatag cagcaattgg gatagctgtc
    40981 tgatcgatat caacatccaa tccaacttct ggatcaatcg attcttcgaa aatcaaataa
    41041 actgcatccc gatcttggtt tttcttaggt gctttgatac gtgcaatccc gtctcctaat
    41101 ccgccaaccg tatctttccc agttgttacc gaagtcccta tttggacaag cctttcttct
    41161 gtgattagct gacggatatt gtttctgttc gtttcagcga tttgctggac gaattcttta
    41221 ggagtcatgt tttcagcagc ttttttttca tgataataat cggtcatgtc gtaaatggca
    41281 aatgtcgctc catttagtgg caccgtctgt gaaatgatat ctgctgtttc ccctgcttcc
    41341 tcagagatag ccaagccatc attttcatgg tattcaaatt gatcgttata atcgatatct
    41401 cgaatcatcc gtttatgcaa cacgaattcc acgacatctt cccctgattc ttctgccgac
    41461 atcgcatgtg gaagaaggac tgctgcaagc ggtagtaaaa caagtaattg aagcatcaaa
    41521 cacaacagct ttttcattac cttgctccct cctttttaga ttgtctgaca aacaaaccat
    41581 aggctgctcc tgcaagcgcc atgaagaatg cagcaagcag gatatagaat aatcgtccgg
    41641 atcctcctgt agcaggcaac ggattttcag gatcgttccc gacactaagc tgtaatctga
    41701 ttcgatttgt ctccaaaagt tcatattcta actcttgctg tagatcaggc gtctctgctt
    41761 cttcgtttgg ataatacgaa atctcaactt ttagtgtacc cgcttctttt cctggaacta
    41821 cccgatcatt ttctatgtca ggttcttctc gataactaat ttctaaaata aagtaacctg
    41881 gaagttttct atagctgtca ggtgacttca cttccttgat ccgatagacc ccttccaaca
    41941 agtctgaagc attgaatagg gaagaatcgt ttggatctgg tgccaagcct ccctcgatga
    42001 tttcatactc tcctgcacta ttttgtttct caattgaaaa ttctgcgcct tcaagacgtc
    42061 ggctattcat actgtcaatt ttcaaaagtt ccaaatcgat tggcgctagt tcatcttcta
    42121 aggttacttg tagtacacca tcgatgattt catagccttc cggcaaggga gcagtttcgt
    42181 cttcgatgac cgtatcttca atgataaact taccttcttc attcagtgca aactggaaca
    42241 cttgatcaga tagccgatac ccatttggtg cgacagattc cgagacctca tattcaccaa
    42301 tagacagatg cagaggttgg tcgtaattta aatcgacata cttttctact cctacggcac
    42361 gagaatagaa gtatccgatc ccaggcaaac gtttcgattc ttctggttct aacggattac
    42421 cagtgtatgc tcgatacagc gggaaggaag aatcccccac tttcctgata tcgaaacctg
    42481 caccatctaa tgtatggcct tcatggtcta attttctaac tcggatctcc cgataatcaa
    42541 acgtattgta agcagtgaat gctacccata aacgatcctc ttcatctgtt gtatacgtga
    42601 gatattgcca attttcttca cctgtttgct tgagttggat agtccctata gcattatcgt
    42661 aaagtcgcaa gatccatgtg tcattttcat caggttcttt gaaaccttct gggttctggc
    42721 tctcaatgat tttgtattct gcatagttgg tagtttcttc actatcctta taaacaaatg
    42781 aatctggctc tccgattgga tgaataactt tctcaccatc cacgattaca tatttcccgt
    42841 cttcatctac tgaatagaac gtgagtctcc ctttctcttc ctctacttcg ttcacaccag
    42901 aaagcccttt cgctactgga tatccgattt ccagtccgtt accatctgtt tcataaagtt
    42961 caaactctgc gccattgatt ggcatattac tgccttcaat tagtttattg atattcatgt
    43021 ggattggctt gaattcattt cgcatttcca gtttgacata caactcatca tactctgtgc
    43081 cttctatgtt aggctcttgt acaacagaaa gcttgtgata ttctccttca taataggaat
    43141 tcggatcttt accttccggt ccgccgactc tcgaaccaga tgtatattca tctacaagct
    43201 cgtagtgacc taacatctca tcttcgttgg ctgcatattt tttgatttgg aattgatacg
    43261 tctcatctac taactgataa cgtggtggtc cagcgatctc tctgatccaa aatatgtcgc
    43321 tgactgctcc agtttcatct cctaaaatcg gcatcttcgt ttcaaagatc gctattccgt
    43381 ccgtggtagt tttacttgtt tcgattggtt cggcttcccc actctctgga ttttggtcat
    43441 ataatgcaaa ttcgactcca gccaacggct cgccattttg acccttcttg ctgacttgga
    43501 aattacggcc tttatgttcg taacgaatgg aagaagatgg gaaatacatc cgtccagtag
    43561 tgatatcatt ctcataatcc tccaggttct gaatataggc catattgttc actgtgcaaa
    43621 aatttccgtc ttgagctccc gcatcaagtt ttacttggta cttgatcctg accatttccc
    43681 cttcacctaa agaaatcgga gaaaatttat aagcttggtt ttcccgtccg acatacgttg
    43741 tcggagtcgc cactacttct ggtggggctt gtccatgacg ttcttcatcc catatttctg
    43801 gctcttggta cttcatgccg ttttctcctg gatctagatg gtaaaactga atatctgccg
    43861 atctgccagc tccaaatggt gagacattaa aaccagtttc atcataaagt gtggcttgct
    43921 ggatcgttct cttgaaggta gaagagatat cctccaaggc tgtaacaatg tcattcttgt
    43981 tgttcgcatt gtaatatcgc ggtgttacgc catcttcttc taaatcagca atatttttca
    44041 atacatttcg tccaatagca tctagtcgtt gtctcccgct aacgtttcca tcgattccta
    44101 aaccaatgga gaagatactt ggcgggttct cttgatactt gtttttcagc caatgatgat
    44161 aagcaactgt gttgatcgca gatgactttt cttgcgaagt aggactgcca ttcgtattgt
    44221 tattagaaga accatcacca acccagtgag tcgctttatt atctccttct tttacctctc
    44281 cataacgata gtgtacattt acttcatctt ctggacggtt aaagtcagat gcataggtaa
    44341 ctggatgagt aaaccctgca ttagaagtat tcccagaaaa ctcctcaaaa tttctgaaca
    44401 aaacgtcatt atcttcagca atcttatctt ccatcacagt ccagttgctc caagctccat
    44461 tagtgctcgt acgataactt gactgaatcg gtgcataact gaaggtcggt gtcccatctc
    44521 ccacaacgat taggattttt tctggatttc tattttctcc gccattgtct ttatacaatg
    44581 tttcatagcc atttttaagc cctagtgtaa gcggagttcc tccgattggt gtacgattta
    44641 atgctgtatt ctcacttccc gtcaaacgat tgatatcatt tgtcaatgga aagatgtccg
    44701 aactgatttg ctcatggtta ttgatagctg tactattatg gtaaaaattc accataccga
    44761 ttcgaatatc cagactcggg tcagagagca gatctttact catttcgttt actgcctcaa
    44821 tcaacgcagc atttttagtt tgactattgg tcccagcggt taattcactc atactcgctg
    44881 acttatctag aacaaaaacg atatcgattg gactgatttc ctttttctcg cccccgatga
    44941 catctagata gacattgtaa agggttgttg catcttcagg atgtagatca gatgctgtgc
    45001 tgcttggcag aacaggttct acccattttt tgatgtacgc cccgttataa tccaagtaac
    45061 tgttttcaaa attccgttca tttccccaaa gctgaacggt ttgagctgga acgtttctat
    45121 cttcttcgcc tgcagttgat ccattattag tagcatagtc gtaatttcgc cagttcgctc
    45181 ccccgtttgt ataatcacta tcatcgatca agttctctcc gtcatatggc gagcctttgt
    45241 ctccttgata gcgttcattg ctttgtgtcc aatttcctaa cacttttgta tagtcattcg
    45301 ttgtaaactt catctattct ttcatcaacc accacttgaa gaggtagtta cccttcgttc
    45361 acatcgggga tcttttctgt ttcaaaaatc aatgtgccgg tttctgcttc ttttgaataa
    45421 acttttccga cataccattc ttgaccatcg atcgtctcga cttttaggtc ttctccatct
    45481 tcatcatagg aggatagacc tgttccacga acgtttttta cggtaccaat cccggcggct
    45541 gccgcatcga ttgctaaacg tattctacct tcattggcac tttccttttt ttcaaaagcc
    45601 agatgccatt caagggtttc ttctttttca atatacttcc cttcaatttt tgcatagtcc
    45661 tcatctaaga atacctcatc ctcctttgtt tctgttgact cagcagctac atccagggtc
    45721 gtcatatgat agactgactg gaaatatggt ccaaatagca aactgacagt tactaactgc
    45781 aaaagcttca attttaaccc tttcacatcc ttatactcct ttcaaaaata tttgtcttct
    45841 ttcacaacaa tcaacaaaac aatgcccatc taattataat ttaatttaat tttaatttta
    45901 aatcaaatga tatccttttt agttaaaaaa caccaattat acaacattta ttattaaaat
    45961 taaattataa aattttataa cgttctcatt taacaaaact taagttatta agacaaatga
    46021 ataaacaact acgctttcct cgaaacaaaa aaataaagca caaatgcgca tttacgcact
    46081 catgctttat tcgtacaatt aattcagata acggcagcgc ataggatgcc aataacactt
    46141 cctaaaatag ctcctcctaa aatgtcagta ggataatgta aaagtaaaaa aatcctcgaa
    46201 taagcgatca aacaagcaaa taaaaaggct aatattcctg caactggact taattcgaac
    46261 aacgcagcta ctgataaaaa ggctagcgct gtatgtcctg aaggaaaaga agaagtcttc
    46321 ggtttacttg tgtaaaggac aagccgacga tttttttcat aaggtctttt ccgtcttgtc
    46381 gtttttttga taaaaagcaa accaacaaaa aaatagatca aactgccgat aagaatggct
    46441 agaccatatt ctctagtatc aggtatcaag actaaaacag cagcaaggag caaccaaata
    46501 aaaccaccat tagagatatt actgataaat ttcaaaaaat tgatttttcg actatccgtt
    46561 ttccgttgct tggcgaactt gttgataata ctatcatcga ttttagcaat caaacgcaac
    46621 atgttattcc tcctttttaa gaaccttttc ttgcgtacga tggataaaaa gcaggacttg
    46681 aaaataaaac aagaaactga aacctaataa agcaaaatag attggtcctg caaaccagaa
    46741 tgcgacaaga aggatcaacg tgcctgccaa atagaaaagc gcgcttttga aatcattaaa
    46801 aaacaagaaa aatgcagtaa tccaagaagc ttctttttgt tccagttgaa gcaagatttt
    46861 gtaactaaag agaagcgcgc ttaatagaag caaaaacaac gtagtataca tcaatgtata
    46921 gccaattccc ccaccccaat agcggaaaat ctgataatcg atcaatagaa gaagaaaata
    46981 aacacttgct aaactatctt gctttccata aaaagagaag ttctcacgaa actttttcca
    47041 gaatagtgaa ccgagctttt tctcttcatt ttttttgtaa tgataaatca tatacagaac
    47101 tgttcgactt gcagttccta atgtgaaaac aggcaagacg cacaggaacc atagtagctg
    47161 taaatggata agacgtggaa tccattcaat gatttctaag aaataatcat tggctttttt
    47221 accaatcgat cgattcatca tccttttgaa cctcctgtca aatccatccc ttcaatgaaa
    47281 taacgttgtg caaaaaagaa cagcaaaatc gtcgggatca agacaagtgt tgctcctgcc
    47341 atcagataat tccattgtgt cgttgcttgg ttctgaaaaa cttgcaagcc aatctgtaac
    47401 gtgtattttt cttgatcttg gatatataac agaggaccta agaaatcatt ccaagctgcg
    47461 ttgaaggaat tgatcgcaat ggtaatcaag gcaggtttcg tcaatggaag catcaaatga
    47521 ctccaaatat acaaatgatt cgctccgtcg atttcagcag cttcgatcaa ttcattattg
    47581 atcgataagt aaaattgacg catcagaaat atattgaacg cattgccgaa gaacgatgga
    47641 acgatcaggg gcaaataagt acctacccag ccgatcttgg agaataatac atattgaggg
    47701 atcatcgtta caaaccccgg gatcatcatc gtagaaagaa ccaaagcaaa catcagcttt
    47761 ttcccaggaa aatcaagctt cgcaaatcca taagcaataa aagaatttga aaggacatta
    47821 ccgatcacta ctagcacagt gatgaataat gtatttcttg catagcgcca aaaaggaaag
    47881 gcggcaatcg tatccagata gttttcccat acgatttttt ctgggaaaaa ggtcggagga
    47941 taacgaacga tttcttccat tggtttcaat gaagtaaaca ccatccaaag caatggaatg
    48001 atcaaaatga ttcctattac tgtcatgagg acataactta gtattttttt tgtttgccga
    48061 ttcacactgg tctttttgaa ataatccatc atttgccgtc acctccagaa taatagaccc
    48121 acttaggtgc aagcttcaaa ttgacaaacg tcagaaccaa cacgatcaga aacaggatca
    48181 ttgacatagc catcgcataa cccatatcaa aagctacgaa cgccttgttc cacatatgca
    48241 gattataaaa aagcaaagaa tttgcaggtc cgcctgttcc atttttcgtc atgacataag
    48301 cttcttgaaa aatttggaaa gaaccgatcg tagaggtgat cacatcgtaa aaaataatag
    48361 gagtgattaa tggcaaagta atacttttga actttcccca aacgcctgct ccatcgattt
    48421 ctgctgattc atataaagat ctaggaacat tttgtaatgt agctaagtaa agtagcattg
    48481 ctcctccaga actccatatt ttcatcaaaa tcaacgcagg tttcgtccat tgtggatcaa
    48541 acagccaagc tggtccaggg atatggaacc agcccagaaa tgtgttgatc aatcctgcag
    48601 atggagaaag cagctgcatc cataagatgt agactgctac tcctgataag actgccggta
    48661 aatagaaagc tgtacggaat acactgattc ctttgatttt ttgattgagt actgtggcta
    48721 aaaacacact gaaaatcgtc gtcagcggta cattgaagat gacgaaataa acggtgttgt
    48781 ataacgattt ccaaaataaa tcatcgtgaa cgaacattct tttgaaattt gctagaccaa
    48841 tgaaattcat cttggatgtc aaattataat cggtgaaact accaataact gaaaaaagca
    48901 taggccctag cataaatacc aagaacccga taataaaagg cgagataaat aaataggccc
    48961 atcttgcttc ttttttcttt cggatagata aacgcttcaa attttcttgc ctcctctgta
    49021 cctagacagt caaaaatgga ttattgattt tgcttgacta agttttctac tgctttttgt
    49081 gcatctgcca atccttcttt tggtgatttt gttcctaaaa gaatctggtc aatctgttca
    49141 ttcactaatg tcgtgtaatc cggagcatct aaaggaactg gtgtgatcac cgtattttta
    49201 aagttttcgt ccgccatttg atagatcatt tttcctttat ccgttaggtt gtcattattc
    49261 actaaattct cattggctgt cttgctcgcc atgatatcaa aacttttttc gccgaatttt
    49321 tcttgtactt ctggagaaga aagatatttg atgaattcat aagaggcctc aggatctttt
    49381 gctccgtatg gtacttccaa gacgaatccg ccaccccacg accaatggcc tgaaccttct
    49441 tctttttctg ggagctgcat cacgccaaaa tcaaaatcat ccggtgcatt ttccatcaaa
    49501 ctagagtaat aattgatatt ttgggcacgc atggctacta atccggaaat aaatggatca
    49561 gatacaccag acccaaattc ggcttctaat ttattgatcg tatttttccc ataataatct
    49621 tgccagtctt ggatccactc caaggcttcc actttatttt tagtatcaat cttgactttt
    49681 tcatctttgt caaaccaact agtcccgtta tctgcgttta gcgcccatac atcagcccct
    49741 aaattccata atggataaaa accgatgcgt gtaaattctt ttccttcttt tttatctagt
    49801 ttacgtgctg tttcttctaa ttcatcccaa gttgtcggta gatcttgttc actgattcca
    49861 gcttcttaaa ataacttttt attataaaaa atgacttgtg tatctgtatt gaatgggatc
    49921 gcataaggat caccttcata ttctactgta tcccaaagct gcggataaaa atccttagaa
    49981 gtgtcttttt ctacatattt ggagagatta gttgcttgct gtgcttctgc tctttgggca
    50041 acggaattta tgtcctgtac aataacatcg ggtgcatttc cagctgttat tgcagataaa
    50101 gatttagtcc agatgtcacc ccatggctga tacttataat ttacatggat ctcgttttgt
    50161 gattgattga aatcctcaat gatttcttcg atagcttctt ttcgtgcacc ggatccccaa
    50221 aaggaccaga aatcaatatt ttttcttcca tcacttgttt tttcagaaga atttgctgca
    50281 cttgaactgg catcgcttgc attacttgat ccgcatcctc ctaataaaaa caatgctgaa
    50341 cttgccagca accctgtaaa caataatttt ttcatatttt acctccaaat tttaatgtaa
    50401 ccgatgccgg ttttaatata acgatatcat tttgttctga aaataacaat ttataaggta
    50461 tgattctaaa aaaattatta atgataccaa tactttatat aattcgcgag cgctttcttt
    50521 gaatttttta atctttcgta gcagaatgag aatgtattaa aaatagatta ggaggaattt
    50581 tgatgtttag acaccagaaa gaattgcagt ttgaagcaaa accagatcgt ccgaatccat
    50641 taatcgcgaa atatctgcag gagctgatcg gcggccaata tggcgagatg agtgtagcta
    50701 tgcagtacct gttccaaggc tggagctgcc gaggagaaga aaaatataaa gatatgctga
    50761 tggacattgc aacagaagaa atcggccacg tggaaatgtt ggcgacaatg gttgctcgtt
    50821 tattagaggg tgcgcctgtt gaagatcaag aagcagcgat gcaaaaagat ccaacaatcg
    50881 gtgccattat ctctggaatg aatccacagc acgcgatcgt agctggctta ggacctcgtc
    50941 ctgctgacag cgtgggcaat ccatggagcg gtgcctatat cattgcgagt ggcaacttgt
    51001 tagcagactt tagagctaat ttaaatgccg aatcacaagg aagacttcaa gtagcacgta
    51061 tttacgaaat gatcgatgat cgtggcgtaa aagatatgct gtctgttctc cttgcaagag
    51121 atagctatca tcaaaatcta tgggaatatg cagtgaaaga attagaagaa aaagaaggtt
    51181 caatcttagt cccaagtact ttcccgcgtg acaaagaacg aaaagacatt gcttatgact
    51241 tctataactt ctcagaggga gaccaaagta gtgaaggttc ttgggctagt ggcaaagcac
    51301 tggatggcga aggcgaatat caatggttga aagaacctaa gatcgaaggc gctgcaccaa
    51361 aattagaacc agtaacacca aaaatgtatg ggacacctcc attcaagaaa taaatatcta
    51421 cccgtagaaa cacccgtttt ttgttccaca cgctttgtga gcaaaactga ctaaagtcat
    51481 taatcataac cacccttcaa aagggtggtt ttctctagag ctataagctc aaatcaccgg
    51541 ccagcgccta aagacgctgg ctttcatatt ttatgttcaa gccatattgc ctttgccagt
    51601 tttgcccacc tcttaaaagg tttatgtact actccttagc ccttaaaagg atcgtcttac
    51661 tctcgtacac tcagcttatc taacgcacta tcatgttttt cttgttcttg aatgtacttt
    51721 ttgatggtcg cttcattttg tcctactttt gtcacatagt atccttccac ccaaaagtgt
    51781 cgatacccaa atttatattt tagatttgca caatctcttg atgatctcct gaatattggc
    51841 tcgatattga ttataaatta tttttcttct atactttggt gtgaatacaa tgtggtattt
    51901 acacatctac tttgtacggg ctaaactatt tccctttatt gctccacccg catagcaagt
    51961 ggttttgtat ttcaatcgct cggcgcgctc aattaggtct aaagacaata aatctaaaaa
    52021 cccgctgctt cactgacaga aacaacgggt tttcagaaaa aaatgaaatg aaaaagatct
    52081 cttacggcaa tctattttat ttttttgatt ttttataaat ggaaaatgct tcaagaagtc
    52141 caagaaataa agccgtataa aaacaagaac ctatgaaatc tttatttatt agatattcaa
    52201 cagaaatccc gataacacta gccaacaata tatttatcag aagtgtaaaa taaggatgct
    52261 ttttatagaa tagaactagt gttgttttca tagactctcc tttcttcata tttccaatta
    52321 atcacaaatt cacggcatta ctagaaaaat taaaggggcg cagaagtgga aaaatactct
    52381 tcgactttcc ctacaaacca ggccatcttg tgtttaataa ctataccaaa tctaaggtac
    52441 ctctaaatct aaattccatt tgtggcggtg acctccaatt tttaactctt ctatctccca
    52501 tccagtatac ataaccttga tacttcgacc acttatatat cgaacacaca aatacctatc
    52561 cattgcagga gtactaccta acttagttgc tacttgcatc taaataacag ctgaaaagat
    52621 aggacttact cttagtaaag tatctgaact attaattttt aaactatcat ttttatcctc
    52681 aactacatgc acatctgttg caacttcact ttctgtctca tccagataaa tgattaagga
    52741 atcgggaatt gcaatatctt cagctgacgc tggaatagtt gagctaaatt agtcatcata
    52801 tctttattat aaaataacca acagcaaaaa atacaatgaa aaacaaactt ggaactaatg
    52861 tatcattaat aaatgttgaa aaattcagca actcattact gtatgatttt agcagcccaa
    52921 ccaacatata ccctataaaa gctaataaga tggttaggaa tcctttagaa tttttactca
    52981 ttcatagaca cttccttaaa taacttttat tatagaaggt attgtaaata ataatattga
    53041 caaaaagtga ctcaaaataa aaaaaaactt acattatact ggaatgaact gtattgatag
    53101 tgtacctaaa agctctactg acataagatc gtgtaatcgg taaagtaatt ttattaatta
    53161 tacgggatgt aatcaattag agaataaact aatcataaaa ggtactttta cattcataat
    53221 tgtcgctttg agattctact ttggttcact atctgaccca attgcacatt ttcgatcatt
    53281 acaagtattg gtgtcgttag aacaactaaa taaaaactag cggtagattt ttcagaatct
    53341 atgctaattt ctgtatggat gttccagtga tggcaaattt ctcttttcat tgtttttctt
    53401 gtcgcatgat atgccttttt gtgttattca gttaaactat agaaattctt tcctagacag
    53461 atcttgatcc caaattttac gtttttgagc atcgatatag tttaaaatga cattactcat
    53521 atctaaagag tttagatttt ttaggactaa aactgtcagt tgttcttttt cttctttctg
    53581 ttaaagtatt gtcgcgactt ttcgtatacg ttaagatatg tcgtgaaaaa acaagttttg
    53641 tgacacaaaa aaacgaatga cttgaggaaa tcacctcaat cattcgttta aaatgctata
    53701 tattctttag tttaagatac ggaaattaat gccatcgacc acactagtag aatgaacgac
    53761 atttacttgg ccttttttta atttcgttat gtttagcata taaaaatatt atagagttta
    53821 cttacaatgc ttaaaacata tactgtataa tctgatcaat tttagccatg tcttgcaatg
    53881 gtaagttttc tatttttttg agttttcgtt ccttaaaatc aagagatttt aattgtgtaa
    53941 taattacttg tccttttata tctagctctt caggtaatga gtaacgtgtc ggtaaattct
    54001 ttatagtgga agtaattgga catatgaccg aaaacattgt tttacggtta aattcataac
    54061 gagagacgac tagtcctggt cgtctttttt gaatttcttt tcctacggag ggatcaaaat
    54121 caatccatac aatatcacct tttttaggaa tataaattct ttcttctgac actataaaat
    54181 ttctctccct tcaggagtta aatcttccca ttcgtctttc tcataatact cggcctcttc
    54241 cccaccacta aatggatctt caatttttgg aactaacgta attgttccat catcagaata
    54301 cacaacgata tattcttggt tttctgaagg tttctttccg ttatcagaag gtaaagttac
    54361 cactacagaa cttccttgta atctagattt tgtaacaagc attatcatca ctcccttaat
    54421 aaaagtatac tatataacac taagtaacgc aaaattcccc tttgtaaact atctagaaaa
    54481 ttgttttgtt taaagtatat cttattggat ataaatagaa ataaattgta gccagttcat
    54541 tttttcttta actaaaaaaa taatccaaga aacattgaac ctatggatcc aaaagctacc
    54601 caaatactat agctaacccc ccgctacctt caattttgca gataaaacgc tttgggagaa
    54661 aatttcaaag acaacaggcc atcctatcat gcccgattat aaacaaaaag ctggctattc
    54721 cttttgctct gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg aagaagtttc
    54781 aactgttcgg atcaaagaat gcccgcttca aatagaaaca ttggttcaac gaatttcaac
    54841 tagacaagac tttgctattg tagaacgtga gatcgtagct atttttgtag aagaagggat
    54901 tttacatgat ccaactcata tcaatgtgga taaatggcaa cctcttatct ataaattcag
    54961 agaatataca actgccaacc agtcgttaac tttgaatttt agattccaag aattcaaaga
    55021 gtcataatga taaacatcgt taggtataaa taaaaaagac tcgcagcacg agtaaaaaac
    55081 aaatagaagc tatacattag aaaggtcgac tgtgacccta tagatgcagt atatgcagct
    55141 tatgagcatt tcttctgttc tctttgtttt tgggatctgt gctgaagtct ttttcgtttt
    55201 ttgccgctct ttctttgaaa aatcgattat gttatacctt ctccattact aattcaggca
    55261 tctgctgagt aatgattttt cgcgcaaaag aaatatctgt tacccaaggt tcgatttgtt
    55321 cttcagtcaa gacaagcggc attcggtcat ggattggtgc gactgtgcgg ttaggttcag
    55381 tagtcattat gattgattct gccatttttt catcctgatg gctacgataa aaaccgccaa
    55441 tatacactat tttttcctta tttgaaaaca taaatttgtc tttttcttca ttccactcat
    55501 tgggaaaaca caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt cttctactgt
    55561 ctctgcacgg gcattaatca tcaattgtcc ttttttaaat ccggtaaatc cccacttcat
    55621 gatttccgga gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa gatttgacgg
    55681 aaaaacttct ccagctgcta attctgctgc ctgcttcggt tgtttcgtct gggcttctcg
    55741 ataataattc tgaaggagct ctgactctag atcaaaaaaa taacgaccac acatcctaat
    55801 ccctcccaat ctttttttct atcatacact gcaacaagaa gttcgcacca acaaaacact
    55861 ttcaattttt gtagaactaa aaaagttgtg acaagtgaca aactctccag tgaatggtat
    55921 tctcctgcca actcctcggt cacaagtcac aatattcaac aaacatgaga agctgctttt
    55981 tgaaattgtt ccttgtgact cggagtgaaa cggcaggctt acgacctctg ggtaaacggt
    56041 gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagctattt
    56101 tcacaaaatt tttcttaata ctcgaaacta agcgactttt tcacaacctc ttccttaaac
    56161 ggtgttcaat cagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc
    56221 tatttttatt tggctgttct tattacttga tgcagggcag ctttttcaca acctctccac
    56281 taaacgatgt tcaatcagct aaccttcggt attagctcaa aaaacggcaa aatatgagga
    56341 actattttgc cgtttgtttc tctaatactc aggtcaaagc gctgatttca caacctctaa
    56401 tacacggtgt tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaatttga
    56461 gaagcaattt tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc
    56521 taattattaa agaacctttt gcgaagttaa caatctttct ttgaccaatt gaaaattctg
    56581 cctaagtagt gatagatcct gtgtgacttt caacaataag atacttccct ggatttcagc
    56641 aatcaacgct ttggcttgac ggtctgcttc ttcatcggac agtttttctt cagaaagtgc
    56701 caggatattt tgtttcgtat acttgaccca ttgattgact aattctagta gcaacagacg
    56761 gtattcttca tccactgtac tcaactcaat aatcaaatta cctacaggac agccatgata
    56821 agtgatctgt gtctcatgat cagcgaaaat ccagtccaac atttcttcta atgcttcttc
    56881 tggctgtttt ccagcattta agatgtcttc gaacaattct gtctgccata cgtccatatg
    56941 cgcatggatc accgctagac aaacttcttt ttttgaagaa aagtaataat aaaattgacc
    57001 ttttcctgta tcagaagctg ctagaatatc tcggattgac gtttcatgat agcctttttt
    57061 ataaataaga tctttggtcg cttccaagat cttttccttt gttttcaatg atattctcct
    57121 ttttcatttc tcatagtcct atattataca gtaaattcat cattttttct tcttaatcgt
    57181 ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac tataaaactg ttctcatata
    57241 gctagatgtt cattgattca agaactgcga ggacaaaagc aattcctatc ttatgatagt
    57301 tgctctaata cttcctctgt tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac
    57361 gctgcatcca ttgcttcttg gccaggagca ccaattgcat ctgtcgctac cacaacattg
    57421 aatccactct ctaccaattc acgcatatgg gaatcgctac acaagtttcc gttcattcca
    57481 ccaagaatta ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc attgctttct
    57541 ggtccaaaga ttttatgagg agagctgatg atcgtatttt catccaaata aggtttcaat
    57601 tcttcgataa aatcggctcc tgaaccttct tccactgatt catattgact ttttctagca
    57661 aacatctgct gctcaagcat catatgttct cctgcaccgc caaattgcca tttatggtca
    57721 tgtgggtaaa aataatgagg agaaataaag agtttgtatc ctttttcttt tgcttgtttt
    57781 accatttcaa tcatattttc gatcgtattg tatttttcta agatatcttt tgtcaaacca
    57841 aagccaccgc ctgctggttt caagaactcg acttgcgggt cagtgagaac tactgctgta
    57901 tttttattat tgaacatggt ggattctcca ttcgttattt attttaatac atcatttaga
    57961 gcttcactca ttgtcggatg agaatagatt tgatctctca ataacgtata aggaagtttt
    58021 ccattcatag ctagcgaaat caagttgatg acttcatgag aatcttccgc atagatactt
    58081 gcccctagaa tcaagtcagt ttcagggtcg actaaaactt tgaatacacc tttaggatct
    58141 tctaatactt gtgctttagg gacaccgctt gtcatatact tgaataattt gtaattgacg
    58201 ccttgtgctt tggcttgttt ttctgttaaa cctacattgg ataaagtcgg agtgataaat
    58261 acactgtaag gcacagcttt ccggttattc gttgttcgtt tattctcgcc cttcaactga
    58321 tccataatga ttcgataatc atctagagag atataagtga actgcaatcc gcctttgacg
    58381 tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt attcatccac agcgattgct
    58441 ccgcgatctg ttagtttaac atctgtattt tctaatccaa gtgatgctgt acttggtttt
    58501 cttccagttg cagccaaaac ttttgacgct tggattgtta cttcttggcc atcttctgta
    58561 aaggtgacgg cagctgttga ttcttggtct gctacttgat ctacagatac acctagatgg
    58621 aattcgattc ccgcatttgt catgtcttct aaaatcattt gcgcgatatc ttcatcttca
    58681 cgtggaagaa attcagaatg ggcatcaaga acgacaactt tagatccgta ttcattgaac
    58741 attgatgcaa attccaagcc aatatatcca gccccgatga tcactaattt ttccggtaat
    58801 tgttcctgat ccatcgcttg cgtagaatca atcaagtagc gacttgtatt caatcctttg
    58861 attggtaaaa tgattggttc agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc
    58921 actttttcac cattattcgt cacttcgatt tgatggttag aaagaaaacg tgctgtaccg
    58981 tccatcactg tcccagttgc ctcatcgctg atcatatgat aatttttggc gcgaagcatg
    59041 cccgtcaatt tttctttccg agcaacagcc tctgtaaagt cgattcctct ttctccattg
    59101 aaaatcaatg atttagaagg aatacagccg atgttgatac atgttccgcc atacatacgt
    59161 gttgactttt caacgactaa aaccgattca ccttttgaag ctaacgcctt cgctaaagtc
    59221 ttaccgccct ttccaaaacc gatcacaata ttttgatatt tttccatcat ttttccctcg
    59281 cttctttttt acctaccgat tggtacaaaa atatgataac cgataattgt ctattctcca
    59341 aatcatctgc tttatttgtc aaaaaaaacc agacaaaaag cggtcctttc acgtttttag
    59401 tctggttcga tttcctttat tcttctaaac aatcgttact tctacatcga tatttcctct
    59461 agttgctttg gagtaagggc agaattcatg cgcatcttct gcaatttttt gggcttcttc
    59521 ttcgctgatg ccatcgatat gcacttcgaa tactacaccg atctgatagc cgccatcatc
    59581 taaattataa agagagacac gtgcttttac tgtggactct gctgtcattc ctgcttcttt
    59641 gatcatatgt tgtaccgccc cattgaaaca agaagcataa cctgctgcaa ataattgttc
    59701 tggatttgtt ccttctgcat ggattcctgg aggagtgatt ttcatatgca tcgagccatt
    59761 tggtgcctcg acttctccat tgcgcccgcc atggttgatc attgctgttt cgtatgcttt
    59821 tttcattgta ctgctccttt cgattgacca tttgctactt ggctataatt atagtgtatg
    59881 acaagtaagg cgctttctac aaaaattctg cttattcgaa taccagaatg ccgtcttcta
    59941 ctatttttcc aaaaaacaaa aaaatactac tcgtgaacaa cagcgtcata tttgttccaa
    60001 aataaatagc aatcttttct acataatctt ttatatgatt gattttaaga tacatatata
    60061 ccagaaagtt gaccccataa accaatactg ttaaaaaaat aaccatattc gttaccattt
    60121 tttcctcctt ttgctggtct ccctaccagc actcgattta accataccac tttttttgcc
    60181 gtccaagcaa ctagcctttc aaaaagactg gtttattctg ctgttaatga ttcaagatca
    60241 gaaaaatgtc cgaataattt tgctaatttt actaacgcca acttgttctt tccgaattca
    60301 tcattttcta tctgtaatac tagtaacggc tcatgtaagc ttaaacggat caaaaaccag
    60361 ccgtttccgt atggctcttc tagatcatat cgaatacctt cttcattttc cgggtcgaag
    60421 ttcatccctt tttcttcttc caacagtcgc ttcatttctt ctaatatctt gtttccttgt
    60481 tcgcgtggtt catcgctgaa caattttaat cggatttctt gtacttctac gggctgtttc
    60541 aactctttga tttgttcatc taatgtgata ccttttcttt ttaattctgg caaaagcatc
    60601 aggatctttg cgatgacata tgcaccatca tccagaaaat agttttcctt gaatgcagcg
    60661 tgtccgcttg tttcgatggc tagctgtgta tctttcccaa gacggttaag ttctaatgct
    60721 ttattgatta catttcgata gccggaaata taacgaactt ggatgcctcc tttttcttca
    60781 atgaatcttt gtagatgaga agaagtaggg gaattcgtca cgattcttgt tcctggatgc
    60841 tcttttaata cgattgtact taatactgcg atcaaattat ttcgattgat cactgttcca
    60901 gaagcactga caactgcaga acgatccaca tctgtatcga aaatgatccc aagatctgct
    60961 tcatttgcta aaacagcctg cttgatactt tccatcgctt ctttattatc aggatttggg
    61021 atatgattag gaaatcggcc atctggttcc aaaaattggg aacctgttga atccgcacct
    61081 aagctattca atactttttc agcaaagaat ccaccagcac catttccggc atcaacaatg
    61141 attttccaac catttagtgg tttgctttct agtgttccaa tccccttttt aatttttgtg
    61201 actaaatctt gcgcataagg tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg
    61261 ctttttattt tttgctgctg tgataggata aaagcaatat cttctttttc tgctcctcct
    61321 tctgaggtaa agaattttat tccattataa taatagggaa gatggctagc agtcagcata
    61381 accgcagcat cgcacgagaa ctgttcaaat tgagtggaca taaacatagc aggcgtagta
    61441 gctaattcga aatcgatgac atgtatccct tgttctttca gactttggat caacgcctct
    61501 ttcagtgctg gtccgcttat cctactgtca tgaccaatcc caatcgtcca ttttttattt
    61561 ggatcggttg atttcttctt tttctttatc cagtttgcta gtccccagcc gatctttttt
    61621 accatgtctg tcgtcaagtt tacttcatat ccttcaactg gtaatgcgat tcctcgaata
    61681 tccgatccat tttgcagcgc tttcatatct ttcatataaa agtcctcctc atttattccc
    61741 tcattttttc cagcttttct gcaaatcgct gtgcttcttc ttctgagcgg caaataataa
    61801 tgaatgtatc tacaccggcc atcgttccga caacttcagg gtaagccact tcatctagcc
    61861 aattcgttac cacatcggca ccatttcgtt cagtcaatac gataaccatg aactgaacag
    61921 actggatacg caaaacctcg cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa
    61981 cagatggctg gttaaataat gtatagcgta ctattttgtt ttcattttga ctttttacta
    62041 acttcatttc tcgaatgtct cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat
    62101 gcagccgcgc aagcagctct tcctgtgtcc caataggttg ttctgtaatg atctggcgga
    62161 tcagtgcttg tcgctgtttc tttttcatat tagacacctc tcaatgttga ttatagcaaa
    62221 agataagtaa tatttcttca tattttggta ttttttactt ttattttttg ttttcattca
    62281 ggttgctaac ctttttctat tttaacacgc aaaatcgtct tcattttttc aggtgctgat
    62341 tttcttggat cgctgatgta aatctctttg tgttctttag aagctctttc atagccttct
    62401 tttgcgatga atgcttctaa tttctcaaac gttgctggtt cttcggcata gggcccgacg
    62461 tgtaagattt gggcacaaag accttcttcc atctttttga atactacttg ttctttcaag
    62521 tcttccggaa gtttgctaga acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag
    62581 tcaggctgtc ggatcatcaa ttgataagaa aaatgttctt ttttcatcac tggttcatgc
    62641 aaatactttt cttgcagtcc ccattgtcct tccagtggat agacagtata catctgataa
    62701 tcaggaatca gccaattttt tttaggcgac atgcgtattg catagctgac tgcatataga
    62761 caggctactc ttcgtttaaa gtcttcctga ttcgggtcgc cgatccctct gatgctaaag
    62821 aatgattttt taggaacctc tagtatttgc gggctttttt tcatactata gctcttgtct
    62881 ttacgccatt caattttttc catttttctt cctccgcgaa attccattta gttatttatt
    62941 atcatacctc tttttgagtg acttggctaa tcgtgttgac actatttttc agtttgtgct
    63001 agaataagtg aagtaaataa atcgtacaga taacacgttt cggcgtgtcg agagagaggc
    63061 ggtttctatt tttataatag aaatcactct ctttttttac gaaatttttt agaggtgatg
    63121 taaatgacaa aacaaaaaca gctgctttta gtacctgcag taattgcaac agggatgatg
    63181 tcttttgcgg gcgtattgat cgagacggcc atgaatgtaa ctttcccaac tcttatcaga
    63241 cagtttgatt taacgactgc acaagtccaa tgggtaacaa cgatttatct tttgatgatt
    63301 tcgatcattg ttccgctgtc tacttatttg aatcgcaatt ttagtctcaa aaaactcttt
    63361 ttagcttcaa atctgctttt cttggcaggt ataatgatcg atttcttctc tcctaccttc
    63421 atggtcctat tgtttggtcg attgctccaa ggtgcagcga caggtatcgc tcttccgttg
    63481 atgttccata ttatcttgac atttgccccc ctcaatcgac gaggcgcgat gatgggtgtc
    63541 ggtactttga caacggccat tgctccagca attggcccca cttatggagg cattatgact
    63601 tcacatttta catggaatca tatcttcctg tttcttgtgc ccgttttgat tctttctttg
    63661 attatcggct ggtttgctat tcccgagatg gcagtacaaa aaagtggtta tttggattgg
    63721 ataagcgttt taggaatttg tcttttgttt agtggaagtc taacattttt gagtacgttg
    63781 ggaacagttt ccagctggat tgctttaatc atcggcggta ttggctggtt ccttttttac
    63841 tatcgaagta aaaaagtgga gcatccactg atccgactgt ctattctttc aaataaaaca
    63901 ttccgcttgt ttttgattgg cttcttagtt tatcagtttt tattacttgg tgtatctttt
    63961 gtcttgccga atttccttca gatcgttcaa ggaagtagtc cttttgtcgc tggattagcg
    64021 atgcttcccg gcgcagcggt tggtgctttg ctttctcctt tttccgggaa aatgctggat
    64081 caatatggtc cgaagaagcc aatttttgct gggctgattc tttctttgat tggttggcta
    64141 gcattattcc tactcatagg acacgcttca gtgggtgtat tgattgcttg tcatgtgttt
    64201 tatatgatcg gtatcggatt atcttacagc aatatgatga ccaccggaat gaatgcactg
    64261 aatgaagaac tacaaggaga cgggaacgca atgttcaata ccttgcagca gttttctggc
    64321 gctgtggcta cttcattagt agcggtcatt atcaattacg tccagcatca tacttcccat
    64381 aactatgaag tgtctactac attaggatca aaagcagcat taggcgtctt gttgctgttg
    64441 cttctcgtaa gctttgctcg attcgcctat tatctgttct ttgctaaaaa agcgtagatt
    64501 ccatatacgg caggtgttgc atctgccgtt tttttgtgtg aaaatggttg tttgtaaaag
    64561 gaggcttttt tatggaaaaa attgccatta tcggtggcgg gatcattggt atgaccctag
    64621 ccagttactt agatacatca aaattcaatg ttgctttatt tgatgaaggg acaggacagg
    64681 caactaaagc tagcgctggg attatctccc cttggttgtc gaaacgcaga aacaaacaat
    64741 ggtatcgtct ggctaaagac ggcgctgctt ttttccctaa acttataaaa gatttccaac
    64801 ttgatcaaac gatttacgca caatcaggga cacttttgct tcgacctgaa aaagatttag
    64861 ctgaattggc tgttcttgcc gagaaacgaa aagaagaagc gccagaaatt ggaaacatcg
    64921 aatggctttc acctgaacag acatctcaag cacttccgtt attgaaacca gcagtttcac
    64981 tgcgtatcag tggtggtggt cgtctggatg gaaaagcata tttagaacat cttggtcagc
    65041 gtttagcaca aaaacaaatg gagcagatcc aggcaaaagt cactttgcat aagaagagcg
    65101 attcttggct catcaaggga ccgtttggag aatacacagc tgatcgtgta attttgacac
    65161 ctggcccggc acttaagcct ttattacaag aattaggcta tgctgcagat atacgtccgc
    65221 aaaaagggca gctcttagca tttcagacat cttataagat gagtcaagac tggcctgttg
    65281 ctatgcttga cggagaagct gatttcattc ctttcatgga tggaaagatc cttttaggtg
    65341 ctacccatga aaacgatcaa ggctgggatt tggctcctac tagcgaagct tataagggat
    65401 tgactaagag tacagaacag ttcttgactg atccagatca gataaaaaac tggccatacg
    65461 agttccgtgt aggtacccgt gcttatacgt cagatttttc cccatttttc ggcgtactgc
    65521 cagatgatcc aagcttactg gctgctagcg gtctaggctc ttctggcttg accacaggtc
    65581 cttatatcgg ctatctatta gccaacttct taaatactgg tcattggcct acggaagatt
    65641 atcaaaagga catctccacc tatattacga aaaatccatc atagaaaaac agctttttca
    65701 agtaaggatc ccgagcgata ttgcgcatgg attacttctt gaaaaagctg ttattttagt
    65761 tcaatttctg aatcaaattc tccaaacttt cttttgcttc atctggcaag agatcttttc
    65821 ctatctgagc ttcaatgaat cgtaaacgaa tatcaagtcg ttgtttcacc agatttttat
    65881 aggacgtatc ctcaaaagaa acaggaaaat ctggtatagg taaatagtgg atgtcttcaa
    65941 atggaccaaa cgacttgaat tctgccgttt gttgcacgat tctttcaacg attgacaatg
    66001 tcgtttcagg tttgattttt ttatcatcga aatatccagt attcaggaca tagcaggctg
    66061 tttgctgttt caaaaacaac tctcgaaaag cttgatagtc ttccctaaga ggatagacac
    66121 ggaaaggatt agcaaatggt tcaatgacta gctcatctag ctgtcttttt gtagtgatat
    66181 tttccgcgtc tgatcgtttt gttgctaatg ttgcaccaaa agacgctgct aaaactgggt
    66241 cattgatctt gataattggc ggaagcgaat catctttcat gatccaaaaa acagcatcga
    66301 tcttttcgct aagatgatcg actcggtcgg gtgtcgcata acgtgatttg actgtccgcc
    66361 catttccgtt tcgtatatct cctgttacta ggactttttc tcctttactt gtacatgtca
    66421 cgcccacatt ctgacaagta aggaaagaag aaatggccgg atcatcagac ggatagtctt
    66481 gtgttttatc aaagtaagaa ggttccaagg cagtagcaaa accatttttt cgagaaataa
    66541 cgaaagcatc gtcatgcaag atcgaaacag agtgaccttc cgtatgtttt gctaaggtaa
    66601 tcgttgattt tccagaaccg gacaacccaa atacagccat cgtataggtc tggtcattac
    66661 tagcatattg tttcatccca ccgtggcagg caataaagcc attgcgattt cccaatgccc
    66721 aagcaagcgt caaagtcgct ttttttaatt ctccaaagta acgtaatcct agcacaaccg
    66781 ctgtattatg gagagcatca aacaaaatga gtccatttgg aaatgtttca tgtgtccatt
    66841 cgggatcaca aaagatataa agatctccct catcaaagga aacagacttt tgataagtct
    66901 ctaagatctt cgaattcgct ggctgaaaat tcagcaaata agaatacaaa ttgttctcaa
    66961 atccttctgg aatcagcaaa tgactttgca cagaaaattc ttcagatagg ccaacgatta
    67021 cttttgtatg gtaaaactgg cgcttgcgac tttgatacac agcttctctt aaaattttct
    67081 cgtatttgct ttgttccttg tctaagtcct caaagatccg ccgagcactt gctgttcttc
    67141 ccacaatgct tccatcattg aatactagtg tcctaacatc agctggtaaa tctagttctt
    67201 cagcatgtga gattgttaaa tctgtgatga tcgttcctgg actccctttt gctagttgat
    67261 aagctgtctt cctatcaaaa acttcatgaa cattattacc gtaaaatgtc gtttctacaa
    67321 tcgatcgaat actggataac agtggatttc cacttgtgat ttcgtttaat tcgagactct
    67381 cttttgtact catggctcct cctcattccc taaacaaaaa aacgttttct ttattataca
    67441 ttattcgagt ttttatttgt actgctgcgc tgtgggaagc aaacgagtta tttttcacac
    67501 aaaaaaaccg agaacttgaa taaacaagtt tctcggtttc atcattttcc ttttatcggc
    67561 ttagtaccag ccgtttgcta accagaatgt tttagcagca tcccatgaac cataacgaga
    67621 tgttacatat tgttctgcta cacgttcttg attggcagct gaatagtcgc cgtttaagta
    67681 tgaagcatct aattgataac ggccgatgta acgtccgtta gtagctgtgt atgaaccgcc
    67741 tgattctttt tgtgcgatcc attcttttgc agagcttgaa gttggcgctg ttgcagcagc
    67801 tggggcagca ggagctactt caactgtttc aacaggtgca acgtatgtat gttcttgcgt
    67861 tgctgtttca gttgtagatg ctgtattttc tgttgttttg ttttctgttg ttgctgaaga
    67921 atcatttgaa gttgggattg ttaattgttc accaacataa atgcggttga tgtttgcgat
    67981 cgaatttttt tcagcaattg catcgatcat tgagttgtct cctgcaaatt tttgtgagat
    68041 cttagataat gaatcacctg attttactgt ataaacttca tcagcgtgag catttgtagt
    68101 tcctacaaac attgcagtag caccagcagc aaaagttgta cctaaaacaa ttttcttaaa
    68161 tgaattcata ttaaactcct ttttttctcc gttttttatt ctttcgacgc tattaacttt
    68221 atcatttaga aatatttcat aggtaaaaga aacatgacat ttaatgacaa aataacgaat
    68281 tatttaatat ttgtaacatt taaacaaata tttttttgat acaaaaccat aaaagccttg
    68341 ttgtataagc aaagtaatcg tttttctatg ttttttttat ttttgaatga aaaacgcaga
    68401 ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa aaaaattttt gatttttatc
    68461 aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag taattgttac aacaattact
    68521 ggacaaaaac tttgaataat gttaactatt tttttatttt aactttctcc gcaataattt
    68581 ctgggcatgt tccaattcgt ttataacgac ttcttctgtt tctttagcta atatttcatc
    68641 taatacatca agccattttt ccggttcttt tgttcctaga cgtccaatag cccaagctgc
    68701 tgttcctctg atgacagggc ggacatctgt taaacattct gaaatctcag gcaatgccgt
    68761 tcgatcacct agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt tcttcccacg
    68821 ccatgaacca gctaaatgcc caaattgctg tttgaagtct ttattagaca tcgaaagcat
    68881 tggctttaat tttggatata tttcgtctac ttttggttcc atctcttcat gaaaatgaaa
    68941 atcttttcct tgattgtaag ggcagactaa ctggcagata tcacatccat aaatgacatt
    69001 tcgcattttt ttacgatatt cttccggcat catccctttt gtctgagttt gataagacaa
    69061 acatcgctgg gcattcattc ttccgtcacc aagcaatgct tttgtcggac aagcagtcac
    69121 gcagcgcata cagtcaccgc aaccaaattc tcctggttta tcaggctcaa atacaatatt
    69181 agtaacgatc tcaccaagat agacaaatga accgaactct tcagtgatca acaatccgtt
    69241 tcgtccaata aatcctaaac cagctcgctg tgctacagcg acatcgatca gttctccagt
    69301 atctacttgc ggagctagac gccattcctc ttctttttgc catttttctg ctcttgtttg
    69361 gatgaattcg atcaatcggt tcaaacggtc tctgagtata tcatggtaat cgatccccca
    69421 agaagcacga gcaaactgcc cgcgtttttc atccctaggc acttcttcat ggatcctagt
    69481 aggatacgca agtgcaatgg aaatgatcga tttcggctga tcaaatgtca tttctggata
    69541 aagacgctca tcgatatttg gatgttcaaa gccagaagta tggccagctg ctttttgttc
    69601 ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga ttttgtcaat
    69661 tcctaatcgt ttgctttctt gtatgatttc ttcttttaat gtcatggtct tcctcgcttg
    69721 ctgttaacgg ctgtataacc cataatatag tttttctttt ttcagctgga caaactggat
    69781 ctgctgatcg gcattcttct tttcttccat ccattttttt cttgcagcaa atacttccca
    69841 ataatttgtt gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat tcaatgaaac
    69901 tggttttgta cttaacagtt catggagcct tacctcttcc catggcgaaa actcagacag
    69961 atcgcgggaa tacaatactt cttcatagag atttttttgc tgtgtgtacg tgaatgtttg
    70021 cgggattttc ccaggcctag caatttctac tagacgatta taaaacatat tcattaattt
    70081 gctgttggca ataaattgac ttttataata ggccgactgg atctttttga ttactccttc
    70141 tgctttgatg actgaaaata atgcaggcca tgctttgacg gttatttcgt cgttttgttt
    70201 aactaatacg ccaggtgtga agccgactgg agaaaggaac acaaaataac cgataccggt
    70261 attttcatct aaaggctgaa attcatcaaa caaccatttg cctatgtaca gctcttcatc
    70321 tggttctgtt gtctcatttt gatttgctat gaataattta gctaattctg cttcaagaaa
    70381 ttgaaggtct tgatccttgt cggtattttc ctgctggctg atcaatcgaa agacttcttc
    70441 tttaatcgta tatttatctt tacgtgtaaa attcatagcc acaccttcct tccttactct
    70501 aactataacg gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc ataatttttt
    70561 ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg cacttttcag
    70621 ctttcttttg tttgtgacaa accttcatgg atcgtttcaa tattccattt catcatctga
    70681 tagtaagaat ctccttgttc tccttctttt gctatggaat cagtgaacag tttatcatag
    70741 attttcaaac ccgtttcttt tgctacccgt tccatgcttc ttgagtctac actggtttcc
    70801 acgaataaaa ccggtacttc ttttgctctt atctgatcaa tgatcgcttt catttgatca
    70861 ggcgtacctt gactttctgt attgatctcc catatataag ctgctggcaa atcatatgct
    70921 cgtgaaaaat acttgaatgc cccttcactt gttactaata attttttgtt ctcttcgata
    70981 gaagcaaaac tttccttcgc ttgtgtatct aattctttta gtttttccac atatgcttct
    71041 gcattttttt tatagagtgt cgcattttct gcatcttttt cagagaatat acgtgcgatt
    71101 tcctccacat attttattcc gttagatagg tctagccaag catggggatc tgcttttgta
    71161 tgttcttcac cgctagttaa ataaagaggt tctacatttt tgctaactgc aaaataatct
    71221 tttccttctt cttttttagc cgtttccatc aagttatcga accagctgtt acctgtttca
    71281 agattcaaac cgttgtataa aataacatct gcatcgcttg cctttttgat gtcttctggt
    71341 agtacttcat attcatgcgg atctgttccg actggtacga tactgtggat atctatttga
    71401 tctgttccga cctcttttgc catgtccgcc aagatcgaat tggtagccac gactgacaac
    71461 ttttctttac ttccttcatc cgcttggtca gaagcctgct ttccgcaacc ggctaatacc
    71521 aagaaactaa ctgccaagat taaaaagagt gatttttttg ttttcatcta tctgcttcct
    71581 ttctgaaata aaattccttt tgttggagaa aataaaaaag caaggataaa aaatgcggta
    71641 catgctaaca cgatcgtagc tcctgatggc caattgtaac tataactgaa aaacacaccg
    71701 acaactgcac ttagcatacc gattcctgca gctgtaatga tcattttcag taaatggttc
    71761 gttagcaagt aagccgtggc ggctggtgtg atcaacatgg caatcaccaa gattgttcct
    71821 actgtctgta aactgactac agccactaat gtcaaaaaga acatcaaaag ataatggatc
    71881 agcgatgtgt tcagcccata agcttttgcc attgtcggat cgaatgatgt gatcttcaat
    71941 tctttataaa agaaaaagac aaatatcaag acgattccac taacgagtgc tgtcagcaac
    72001 aaatcgcttt ccctaacagc taagacattc ccaaataaaa tatgatacaa atctgtcgca
    72061 ctctgggcat atgaaatcaa gataatccct aatgcaaaaa aggagctaaa gacaattcca
    72121 atcgctgtat catttttcaa tcggctccgc tgagtcacga aaccaatcac tgctgctgtt
    72181 agcatcccaa aagcagtggc tccaaagatg taactaaaac caaacatata agaaatggct
    72241 acacctggaa gaactgcgtg agagatagcg tctcccatca aagacatccc tcgtaaaata
    72301 ataaaagaac cgatgactcc agaagcaagt cctacaagca tggaagtgac caaagcgtat
    72361 tgcaggaatt gataattcat taatccatca ataaaggatt ggatcatttt ttctctcctc
    72421 cttttactaa atgtctgatg atctcaccat aggccaattg aaggttcttc gatgtaaaga
    72481 cttcttgtac tggaccggaa gcgatcagct gtttatttaa aagaataacc tcatcgaaat
    72541 attcttctac tttatgaaga tcatgatgga cgatcaaaat cgtttttcct gaattcttca
    72601 attcctgcaa gatgtcaaag atctttcgtt cacttaacgc atcaatccct acgaatggtt
    72661 catctaaaaa gatccattct gctccttggg ctagagctct tgcaataaaa actctctgaa
    72721 gctgtccacc cgatagttcg ctgatctgtc ttttggcata ttcttccatc cctacttttt
    72781 tcaaagcttg tcttgcacgt tctttttctt ttttcccagg tctttgtcca attcgtaaag
    72841 atggatatgt tcctaaaagt acaacgccta atacatcaat tggaaaggaa agatccaatt
    72901 cacttcgctg ttccacgtag gctatttttt tacggactga gtttaccgac tgtccagaaa
    72961 aggtgacttt accagtagta gctggtatca actctagcaa agatttcata aatgttgatt
    73021 ttcctgcacc gtttggtccg ataataccgg taattttttg tggatttatc gtcaagttga
    73081 tagttttcaa aacagttttc ccttgataag cggctgaaag gtcttgaatt acaatggccg
    73141 tacgttccaa atcttacact cctttttagg tttacctaac tttttattta aatatagttt
    73201 aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg aattttcctc
    73261 gcattttatg aaaattttct gtagaatcac atcaagagtt caataaggct aacctaataa
    73321 tgaaaaacat gtgttgaaac gtttgattat tttttcttgt tgactcaaca acgaaaggag
    73381 tttttgtatg gaagaagaaa agttaactcg aagtcttagt gcccgtcata tccaaatgat
    73441 cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa ccatacgttg
    73501 gacagggccc tcagtgatgg gagcctatgc gattgcagga ttctttttgt atttgattat
    73561 gcgtgcttta ggcgaaatgc tttacgttga tccttcgact ggttcttttg caaattacgc
    73621 gagcgagtac atccatcctg tggctggcta cttgaccgct tggagtaata tttttcaata
    73681 tattgtcgta ggaataagtg aagtgattgc tgtaggatct tatatgaatt attggtggcc
    73741 tgatttgccg gcaattattc ccggaatcat tgtcgtcttg tttcttatgc tggcaaatct
    73801 tatttctgtc aaggcgtttg gcgaattaga attttggttt tcgatcatca aagtcataac
    73861 gatcattttg atgatcattg caggtcttgg ggtaatctta tttggatttg gtaatcatgg
    73921 tcaggcagta gggatttcaa atctttggaa aaatggtgga ttcttcactg gaggcgtcaa
    73981 aggatttttc tttgcattat cgatcgttgt tgcttcctat caaggaatcg aactgatcgg
    74041 aatgactgct ggtgaagcag agaatcctaa aaagacgatc attgaagctg tccagtccac
    74101 tatcggtcga atcttgattt tttatattgg tgctattttt atcattgtga gtatctatcc
    74161 gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa actttttcta aagtcggcat
    74221 tacatttgct gcaggactga ttaattttgt cgtgattaca gcggcattat caggttgcaa
    74281 ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt gccataaatg gaaagatgtc
    74341 taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg tagcaatctc
    74401 aggtggaatc ttaattggtc tgatcttaaa ttatcttcta ccaatgttca tcaaccagtc
    74461 agaaaatatt ttcgttttcg tatacagctc aagtattttg cctggtatgg ttccttgggt
    74521 agtgattttg atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa tgcatgatca
    74581 tccttttaaa atgccactat ctccttatac gaattatgtg acacttgctt ttttagctat
    74641 cgtattgatt ttcatgttta tcaatcctga aacgagaatc tcattgatta ttggactcgt
    74701 tttcttgctt tacatgacga tccattactt tgtacgcgaa aaaagaaccg gaaaataaaa
    74761 aaagaacgaa gcttcacctt agtggaagct tcgttctttt ttattgcttt tatcaattca
    74821 attttagcgt ctcaccggga gtcaggaaat aattctccat gctcatccca ttcagcgaca
    74881 agatcgtttc tactggtacg ccagttcgtt cggctatttg atttggacct tctccttcca
    74941 aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca gaggaatctg
    75001 ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc taccgactct gctgtctcag
    75061 aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag gcgctagtct
    75121 gcaaataaat atcggaaatc ttagcgacat gattcgtata attagccgat aattgattga
    75181 tcaaagtatc taagtctaca ccgtctttat tttctgctgc ctgatacgct gcacgtaatt
    75241 ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc tttttggtta gcaactgctg
    75301 ataaaccagc tattccctct tgatttccct gaatttctgt ctggtattct tcaatcaatg
    75361 caggcgtctt ttcttcgatc tttttcgaat aatcatttac gattgcttga agttgctctg
    75421 gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc ttttgtttta gttgatgact
    75481 cacttgtttg tttcgtctct gttttctttg tcgttgtttc cgttatggtc gtacttttcg
    75541 cttctgacga attttttcca tgaaaatata gacccgcaac tcctcctgct atgatcaaaa
    75601 acacggcaac tgctgcccca atcatgatca tccgcttacg agctgcctgt ttttgctgtc
    75661 ttcttcgggt catccgaaca ttttctcccc actcattttc atcatacatt tttttcacca
    75721 ccaattttta tgtataatag cgttatcaaa cgcttcatat tcttattgta gcaaataatt
    75781 gtcgctgtgc acatttttat ctttgttatt tataagaaaa tttcaccagt tgagatgatt
    75841 ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta tctcagccat
    75901 cagtttcttt atttcatata agagcgcacg gtcttgatat tctgattttt cgcttaattc
    75961 atctaattgt tggatcagcc aatcatttgt cataatgaag ttcctttcat ttcttgcagt
    76021 gtaaaggtca agtcttcgat ctgctctttt gcctcagtca gtgcttctac gatatatgct
    76081 tgtttttcag attcttcttc ctgcattttc tgattttcct gtactctttg aataaaccag
    76141 tcaatccgct gagtcagcga tggtttgcct tccaatgaga gatactgctg ataagcaatt
    76201 agcttctccc aacgtttttc ctgggataaa tacataaatt gtgctaaaac gaatggcgga
    76261 agataggtca tatggaattt atttgcgatt cgctgatacg gcctcaaaaa ttcggaaatc
    76321 gtatattctt cttttcctcc agcttggtat tctttttccg ccacacctgt tgtcaatacg
    76381 attcctagtt ctttcccttt taatacatgt gctgctcgtt ccaagacatt atcttgccaa
    76441 atttttaaat gagcaggaga actataccag taaaacggaa actggaaaat gatccgatca
    76501 tgctgggcca agagctgtag ttcagtctct atatctattt ttccgtctgg ataacttgat
    76561 tccaaatgat gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa ttgctgattt
    76621 aaagattctt cgatcgttgg atggctaatg atgataagtg tacgcatccc ttttcctcct
    76681 ttttagtctt cgctttacag tgtagcataa ccgccacaag tttcttttgc cgatgcttgt
    76741 cattttaacc agactaatca ggttgtccaa gaaactgtgg tttgtttttc caactgtttt
    76801 ttcaaggtat ccaaagcaat attcttaaaa tttttgtttt tcatacgttt acgatagttc
    76861 gtagccgttt ctccggtact ctttttgaac attcggctaa atacgactag actattgaac
    76921 cctacttgat aggcaatact ttccacggat tcatccgtca gagaaagaag aaacgcccct
    76981 cgattgatcc gtaccccgat caaatattcc ttgatactgg tacccatatg atttttgaat
    77041 actcgcgaca aatggctccg attgaccgct aaatgctggg cgatttcctc aacagacaat
    77101 ttttcagcat aatgtgcctc gatgtatttg actgtttcaa cagctaaaga ggaatgaacc
    77161 ttttgtacac caccgctgac ctttccgcca tcttttaaaa ggactgataa aaaacggtag
    77221 gttaatgctg ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt catgcattct
    77281 aaaataatgt cgatatattt ttgtatgtca gaagagacca tcgtgtattg gtcttctctg
    77341 aaaagcgact gccgaatgat ttcttctgca gcactcccac caaatgaaag ccagcaatac
    77401 atccacggat cttctccatc tgataagtaa aacgtcgagt ctcctggacg aatcaagaac
    77461 agatcacctt ttttcaattg gaattgttga tttttcacat gataagatcc tttgccttcc
    77521 atcacgacat gcaggatgta atcattgcga atagcaggac caaaagaatg aaacggcatc
    77581 gttttagaga aaccacaaaa atcaaaatac aattcttttt ctacttgttg atgttccttt
    77641 tttaaaaaaa tcgattgctc cacgtctatc cctccttact cctttagtat aatgcaacaa
    77701 aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg ttaagtttaa
    77761 gtcattaaaa gatctttgtt attcgttgta accggtttac ttagtattat atattgaaca
    77821 ggagaggaat acagattatg aaaagcaaaa tgatccaacg tgtgtcctac gctttaggcg
    77881 cttttggaca cgacacattc tatgttacat taagcactta ttttatggta ttcgtgacaa
    77941 gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct acagttacaa
    78001 gcttagttgt aggtatccgc ttagttgaaa ttatttttga tcctttgatt ggtggcatca
    78061 tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc ggcggcgttg
    78121 ttagttccgt actcttggta gcaatcttta ccaatttctt tggcttagct actcataata
    78181 cgactttatt tatcatatta tttgcaatcg ttttcatctt attggatagt ttttattcat
    78241 ttaaggatat cgctttttgg tcaatgattc cagctttgag tacggaaaca aaggaacgtg
    78301 aaaaatttgc tacgtttgct cgtttcggct cttctctagg tgcaaatggt actactctag
    78361 tcgttgtccc tatcgttact ttctttacct atcttgttac tcataaacat attgaaggcg
    78421 cttcaggctg gttctggttc ggtgtgattg ctgctgttat ttcaggcggt actgcgatta
    78481 tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat gaaaaagctg
    78541 ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg cttgcccttg
    78601 cttatatcgc ttatgcgatt gccaatgcag caacaactgc cgtattattc tacttcttca
    78661 aatatgtact tggccaacca actgaatttt ggatcgttgg tctagttgct gccttacttg
    78721 gtttagtagc tgttccacta ttcccaatgc ttacacgcgt catctctcgt cgctacgttt
    78781 accttggagg gatcgcaatg atgatttctt cttacttttt ctttacgatc gcaggttcaa
    78841 gtttgccaat cgttatcatc gggctagtat tgttctactt ccctcaacaa ttgattttct
    78901 tatccgcttt gatgacgatc acagactctg ttgaatatgg tcaatggaaa aatggtatcc
    78961 gtaacgaagc tgttactcta tcaattcgcc ctttactaga taaaatcgct ggtgctttgt
    79021 ctaacgggat cgtagggttt gtcgctatcg cttctgggat gactggtaat gctactgctg
    79081 ctgatatcac tgctcatggc gtaacgactt tcaaagctta tgcattctat gctcctgctg
    79141 ctttgatgat tttctccgct attatttttg cttggaagat tacattgaca gagaaaaaac
    79201 atgcacaaat cgttgagaaa ttggaaaaca aattggctcc agctgataca atggaagatg
    79261 aacttcacga tgcagtagat ccttcccatt aagaaaggat cttgaaaatg aagattacag
    79321 aaaaagattt tggccaaggt tatcacttga taaccttgga gaacaaaaac aagctagcac
    79381 tttctatctc tgatttaggt gctagaatcg tcagtttaaa atcaaatgat cgagaattag
    79441 ttttgggatt tgacaccgct gaagaatata tcgaaaaaga tccgtatatc ggtgcttcta
    79501 tcggtcgcac cgcagggaga atcgaaaatg gccacttttc tctcaatgga aaaacttacc
    79561 aattagccac agatccaaaa actggacata atctgcatgg tggtgctcct ggatttgaat
    79621 taaaaaaatg gtcttatgtc attttgaatg gcgaaaatga agcttctgtc atttttacta
    79681 ctacaagtcc cgacggagaa catggttttc caggtacaat ggatgtggaa atccgctata
    79741 ctttgacaaa agataatatc tggcgagtga cctctcgcgg caccagtgac caagatactt
    79801 tattcaatcc gacaaatcat gtttacttca acttgacggg agatgcttct cagtcaatcg
    79861 atcaacatga gctttggctc aatagcgaag cttatgctcc tttgcgaaca gatagtattc
    79921 ctataggggt aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata cctaaaaaat
    79981 tagcgtccgt ttttgctagt gatttggatc aaaaaaatct tgttgacgga atcgatcatc
    80041 catttttctt aaaagaaacc ggcttgggta aagaagccgc tcgcttgact agccccgata
    80101 aaagaatcca agtagatatt gctacagatg cttctagtgt ggttattttc actgcaaatt
    80161 tcggcacaga aacaccagaa atgcgcaacc gaaaactggc acatcacggt ggcatcacat
    80221 ttgagactca aacagctcca ggtgcagagc gcttctcagc atttggttcg attcatttaa
    80281 aagccggatc agtatttgaa acagtgacag aattcaaaat caaaacaaga aaggaataac
    80341 tcatcatgga aatcaaaaga agcttaaaca caaaatttgc cgaaacattc ggacctaaaa
    80401 aaactacaca atacttctca ccaggacgca tcaatttgat tggtgaacac acagattaca
    80461 atggaggcca tgtcttcccc gcttccatca cttatggaac gcaaggtgta gcagcacctc
    80521 gagacgataa taaaatatta gtttattcca caaactttga cgatatcggt gtcattagtt
    80581 ttactttaga tgagctagaa tatgataaaa aagcaaactg ggcaaattac gtaaaaggaa
    80641 tggtccttaa attaaaagaa gctggacact caatcgatca tgggtttgag ttattagtgg
    80701 aaggaacaat ccctaatggt gcaggacttt ccagtagcgc ttcattagaa ttattagtag
    80761 gtgttgtatt agaagatctg tttgatttaa aaacagatcg cttggaacta gtccaaacag
    80821 gtaaaaaagt agaaaatgaa ttcatcggtg tcaattcagg tatcatggat cagtttgcca
    80881 tcggcttcgg tgagctagat catgcaatct tattagatac aaatacgctg aaatacgaaa
    80941 tggttccagt gaaactagat ggttatgcaa tcgtcatcat gaatacgaat aagcggcggg
    81001 aattggcaga ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc ttggcacgtt
    81061 tgcaaaaaac tttgcctatc tcttctttag gagacttaga tgaagaagaa tttgaatcaa
    81121 ctattgacca aatcggcgat gatacattga tacgcagagc tcgccatgcc gtttctgaaa
    81181 atcagcggac tttgaaggca aaagctgaat tagaagctgg gaacttagaa gcatttggtc
    81241 aactgttaaa tgattctcac cactctcttc gctatgatta tgaagtaact gggatcgaat
    81301 tagatacact agtagatgct gctcaaaaac aagaaggtgt cttaggtgca cgaatgacag
    81361 gagctggatt tggtggctgt gcgattgctc ttgtcaaaga agaaaatata cctgccttca
    81421 aaaacaatgt ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa ttttatgttg
    81481 cacacattgg aaatgggaca acaaagatcg atccagaagc tgttcatgtt tgataaaaaa
    81541 atcaacgatc tcagctaaaa acaaatagat aaaaataacc tctcagcaat ttccaaatgt
    81601 gagccttttg ctcgtatttg aaaattgctg ttttttattg acacggaaag agaacgtgtg
    81661 ttctaattgt gttgaagagg tgattgttat gtgggcgaat caaaatccgg tatttgttta
    81721 tgaaaaagaa ccttcaagag atattttatg tattgactgc aaatcttttt acgcctccgt
    81781 agagtgcgtt gaaaaggatc ttgatcccct tacaactaaa ttagtagtca tgtcctatcc
    81841 gtccgattcg acagaaacac ggggtagcgg attaatcttg gcttccagtc ctgcagcaaa
    81901 aaaagcttac ggcatcacca atatcagccg tgccagagat cttcccttcc cctatccaag
    81961 tgatttatat attgttgccc caaggatggc ctattatatg gaaaagaaca gagaaatcaa
    82021 ttctatctat aaaaaatatg cagacgaagc gaaccatcat gtctattccg tcgatgaaag
    82081 cttccttgat gtaacaaata gcatggcact ctttggtaaa acaaatgcgt acgacatggc
    82141 taaactgatc cataaagatg tgtttgagca gaccggaatc tacacgacta taggaattgg
    82201 cgataacccg ctacttgcta aactagcctt agacaatggc tcaaaagacg gaaagcaaat
    82261 gtttgctgaa tggcgttatg aagatgtacc agaaaagtta tggaaaatct cagatatcac
    82321 tgacttttgg ggaatcggca aacgaacagc aaaacgtctg aaacaaatgg gtatacattc
    82381 tgtttatgat ttagctcacg cggattatta tcacttgaaa agcaagctag gggtcatcgg
    82441 tactcagctt tatgcccatg cttggggcat cgatcgaagt tttttgggac aagaatatac
    82501 accaaaatca aaaagtatcg gaaatagtca aatcctagat agagattata caagacgaga
    82561 agaaatcgag atcgttatca aagaaatggc cgaccaagtc ggcactcgct tgagacgatc
    82621 tgcagcaaaa acacaagtag tcagcttatg ggtaggatac tctttaggct atcttgatcc
    82681 aaatggcaag accgggtttc accagcaaat gaaaatcgaa gcgacaaatg ctagcagaga
    82741 tctagcagat gctttattga ccattttcca ccagcattac cactaccagg atattcggcg
    82801 tgtaggcgtg aactgttccg acctcgtata cgcgacaggt ttacagctta acctttttga
    82861 agatcctgaa aagcagataa atgaagcgaa agttgatttt gttgtcgata cgattagaaa
    82921 aaaatacggc tttcaatcaa tcatccatgc gcatagtctc ttgcaaggag gacgcgccat
    82981 cgcacgtagt tctctcgttg gcgggcatgc aggtggtatg agtggattag aaggtggaaa
    83041 agatgagacg gacagcaaaa aaattcattg actataacga gtatcgagat cggccatttg
    83101 gattaaaatg ggggactgct tttgcgatgg aagaactagt caacggtatc aaaaaaaatg
    83161 aagaagaagc acgcaaacag cctcttccta aacaacaaat gacattgcaa gaaatcgata
    83221 gtatactgac agaagccttt ttatctcgta aagcagtaat cattcagctc aatttaaaag
    83281 atgaatttgg aagactcttg gatgaggtcg aagggcactt cattggtgaa gcctatgaag
    83341 attactttat gattgaccat cagccgatat tgtgggaaga cgtacggtat attgagttaa
    83401 aggaaacaaa aaaatggttt gtgacatgag aggttgtgac agaagtgatc aacttcaaaa
    83461 aataagaaag gatttttcga aaattgcttc ttaaattttt gtggaatttt ggcttatttt
    83521 tcgaagaagc aacttctgga acaacgtata ttagatatca gaggttgtga aaaagtcgct
    83581 tagttttgag taacaagcca aggcgctgat ttcacaacct ctgtctatct atccatctat
    83641 tcggtaagat tcatgcatga cgtcttcttt atttagtatg tagagccctt tttcttctga
    83701 ccattcaaca taaatcagct gttttacatc tgcatagcct tctttcttca agttctccat
    83761 aagccatgct tcagtcaatt gattggactg aagcacttta tgctgaattt gcccttcatc
    83821 tacaagcagg atcgataaag ctttgtcttc atctgatttt ttcaatacac tcatttgacc
    83881 ggcattctct aggataacat gtttggcatt ttcaagaaaa aagcattctt gctgtcttaa
    83941 gattgctcgc aactgctcca tctcgatatg gttatttgtc aactctgtca tgttgatgac
    84001 gccgtctttg attagaacag atggctcgcc tttgacccaa cgattgacct tttcattttt
    84061 ttggacgata cgttcgatac cataaatcat tactgcccaa agcgcaatgg caaataggac
    84121 atgccctaca tggacattgt catcataggt tgattcttct aagatcccac ctaaaacaag
    84181 cgtatagact aaatcaaacg gtgtgatttc tgacatggat ttcttcccaa gcaaacgtac
    84241 cactaataat aaaccgatca acccgaacac cagtttcatt gtaattgaaa aaatcatttt
    84301 ttctccccct aactatctgt taattaaatt atatatgctt tctcacgaac acgcatggaa
    84361 tatacaagga agaaatgtat ccttttacta aaaaaaggac tgtgacactg tagtgacccc
    84421 caaaagttag acttttttgg agtggagaaa tccactcctt ttttttatgc tctaaaatga
    84481 tatttttaca caaccgttac ggttgtttta cgaaattgga cg
//
LOCUS       DASHWW010000005        80741 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.005, whole genome shotgun sequence.
ACCESSION   DASHWW010000005 DASHWW010000000
VERSION     DASHWW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.005"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(108..461)
                     /locus_tag="U2R64_000403"
     CDS             complement(108..461)
                     /locus_tag="U2R64_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917249.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            992..1414
                     /locus_tag="U2R64_000404"
     CDS             992..1414
                     /locus_tag="U2R64_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8917250.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            1411..1641
                     /locus_tag="U2R64_000405"
     CDS             1411..1641
                     /locus_tag="U2R64_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917251.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2139..2339
                     /locus_tag="U2R64_000406"
     CDS             2139..2339
                     /locus_tag="U2R64_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEM8917252.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            2366..3559
                     /locus_tag="U2R64_000407"
     CDS             2366..3559
                     /locus_tag="U2R64_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8917253.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(3627..5192)
                     /gene="guaA"
                     /locus_tag="U2R64_000408"
     CDS             complement(3627..5192)
                     /gene="guaA"
                     /locus_tag="U2R64_000408"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEM8917254.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5251..6174)
                     /locus_tag="U2R64_000409"
     CDS             complement(5251..6174)
                     /locus_tag="U2R64_000409"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEM8917255.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            6370..6975
                     /locus_tag="U2R64_000410"
     CDS             6370..6975
                     /locus_tag="U2R64_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8917256.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7283..8299
                     /locus_tag="U2R64_000411"
     CDS             7283..8299
                     /locus_tag="U2R64_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEM8917257.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            8440..9741
                     /locus_tag="U2R64_000412"
     CDS             8440..9741
                     /locus_tag="U2R64_000412"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEM8917258.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            9787..10449
                     /gene="deoC"
                     /locus_tag="U2R64_000413"
     CDS             9787..10449
                     /gene="deoC"
                     /locus_tag="U2R64_000413"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEM8917259.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            10470..10868
                     /locus_tag="U2R64_000414"
     CDS             10470..10868
                     /locus_tag="U2R64_000414"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEM8917260.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            10934..12016
                     /locus_tag="U2R64_000415"
     CDS             10934..12016
                     /locus_tag="U2R64_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917261.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12228..13790
                     /locus_tag="U2R64_000416"
     CDS             12228..13790
                     /locus_tag="U2R64_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917262.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            13783..14916
                     /locus_tag="U2R64_000417"
     CDS             13783..14916
                     /locus_tag="U2R64_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917263.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            14916..15872
                     /locus_tag="U2R64_000418"
     CDS             14916..15872
                     /locus_tag="U2R64_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917264.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            15971..17137
                     /gene="deoB"
                     /locus_tag="U2R64_000419"
     CDS             15971..17137
                     /gene="deoB"
                     /locus_tag="U2R64_000419"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEM8917265.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17161..17979
                     /locus_tag="U2R64_000420"
     CDS             17161..17979
                     /locus_tag="U2R64_000420"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEM8917266.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            17996..18703
                     /gene="deoD"
                     /locus_tag="U2R64_000421"
     CDS             17996..18703
                     /gene="deoD"
                     /locus_tag="U2R64_000421"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEM8917267.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19001..19687)
                     /gene="gpmA"
                     /locus_tag="U2R64_000422"
     CDS             complement(19001..19687)
                     /gene="gpmA"
                     /locus_tag="U2R64_000422"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEM8917268.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(19859..20440)
                     /locus_tag="U2R64_000423"
     CDS             complement(19859..20440)
                     /locus_tag="U2R64_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8917269.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(20573..21256)
                     /gene="rpiA"
                     /locus_tag="U2R64_000424"
     CDS             complement(20573..21256)
                     /gene="rpiA"
                     /locus_tag="U2R64_000424"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEM8917270.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            21575..21988
                     /gene="rpsL"
                     /locus_tag="U2R64_000425"
     CDS             21575..21988
                     /gene="rpsL"
                     /locus_tag="U2R64_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEM8917271.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22072..22542
                     /gene="rpsG"
                     /locus_tag="U2R64_000426"
     CDS             22072..22542
                     /gene="rpsG"
                     /locus_tag="U2R64_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEM8917272.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            22636..24723
                     /gene="fusA"
                     /locus_tag="U2R64_000427"
     CDS             22636..24723
                     /gene="fusA"
                     /locus_tag="U2R64_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEM8917273.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            24895..26082
                     /gene="tuf"
                     /locus_tag="U2R64_000428"
     CDS             24895..26082
                     /gene="tuf"
                     /locus_tag="U2R64_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEM8917274.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            26489..26797
                     /gene="rpsJ"
                     /locus_tag="U2R64_000429"
     CDS             26489..26797
                     /gene="rpsJ"
                     /locus_tag="U2R64_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEM8917275.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            26828..27457
                     /gene="rplC"
                     /locus_tag="U2R64_000430"
     CDS             26828..27457
                     /gene="rplC"
                     /locus_tag="U2R64_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEM8917276.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            27485..28108
                     /gene="rplD"
                     /locus_tag="U2R64_000431"
     CDS             27485..28108
                     /gene="rplD"
                     /locus_tag="U2R64_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEM8917277.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            28108..28398
                     /gene="rplW"
                     /locus_tag="U2R64_000432"
     CDS             28108..28398
                     /gene="rplW"
                     /locus_tag="U2R64_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEM8917278.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            28437..29270
                     /gene="rplB"
                     /locus_tag="U2R64_000433"
     CDS             28437..29270
                     /gene="rplB"
                     /locus_tag="U2R64_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEM8917279.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            29313..29591
                     /gene="rpsS"
                     /locus_tag="U2R64_000434"
     CDS             29313..29591
                     /gene="rpsS"
                     /locus_tag="U2R64_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEM8917280.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            29614..29961
                     /gene="rplV"
                     /locus_tag="U2R64_000435"
     CDS             29614..29961
                     /gene="rplV"
                     /locus_tag="U2R64_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEM8917281.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            29975..30631
                     /gene="rpsC"
                     /locus_tag="U2R64_000436"
     CDS             29975..30631
                     /gene="rpsC"
                     /locus_tag="U2R64_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEM8917282.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            30634..31068
                     /gene="rplP"
                     /locus_tag="U2R64_000437"
     CDS             30634..31068
                     /gene="rplP"
                     /locus_tag="U2R64_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEM8917283.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            31058..31246
                     /gene="rpmC"
                     /locus_tag="U2R64_000438"
     CDS             31058..31246
                     /gene="rpmC"
                     /locus_tag="U2R64_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEM8917284.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            31271..31537
                     /gene="rpsQ"
                     /locus_tag="U2R64_000439"
     CDS             31271..31537
                     /gene="rpsQ"
                     /locus_tag="U2R64_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEM8917285.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            31595..31963
                     /gene="rplN"
                     /locus_tag="U2R64_000440"
     CDS             31595..31963
                     /gene="rplN"
                     /locus_tag="U2R64_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEM8917286.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            32000..32308
                     /gene="rplX"
                     /locus_tag="U2R64_000441"
     CDS             32000..32308
                     /gene="rplX"
                     /locus_tag="U2R64_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEM8917287.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            32336..32875
                     /gene="rplE"
                     /locus_tag="U2R64_000442"
     CDS             32336..32875
                     /gene="rplE"
                     /locus_tag="U2R64_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEM8917288.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            32894..33079
                     /locus_tag="U2R64_000443"
     CDS             32894..33079
                     /locus_tag="U2R64_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEM8917289.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            33115..33513
                     /gene="rpsH"
                     /locus_tag="U2R64_000444"
     CDS             33115..33513
                     /gene="rpsH"
                     /locus_tag="U2R64_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEM8917290.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            33545..34081
                     /gene="rplF"
                     /locus_tag="U2R64_000445"
     CDS             33545..34081
                     /gene="rplF"
                     /locus_tag="U2R64_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEM8917291.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            34242..34598
                     /gene="rplR"
                     /locus_tag="U2R64_000446"
     CDS             34242..34598
                     /gene="rplR"
                     /locus_tag="U2R64_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEM8917292.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            34619..35119
                     /gene="rpsE"
                     /locus_tag="U2R64_000447"
     CDS             34619..35119
                     /gene="rpsE"
                     /locus_tag="U2R64_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEM8917293.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            35134..35313
                     /gene="rpmD"
                     /locus_tag="U2R64_000448"
     CDS             35134..35313
                     /gene="rpmD"
                     /locus_tag="U2R64_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEM8917294.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            35357..35797
                     /gene="rplO"
                     /locus_tag="U2R64_000449"
     CDS             35357..35797
                     /gene="rplO"
                     /locus_tag="U2R64_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEM8917295.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            35797..37092
                     /gene="secY"
                     /locus_tag="U2R64_000450"
     CDS             35797..37092
                     /gene="secY"
                     /locus_tag="U2R64_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEM8917296.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            37154..37801
                     /locus_tag="U2R64_000451"
     CDS             37154..37801
                     /locus_tag="U2R64_000451"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEM8917297.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            37992..38210
                     /gene="infA"
                     /locus_tag="U2R64_000452"
     CDS             37992..38210
                     /gene="infA"
                     /locus_tag="U2R64_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEM8917298.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            38243..38359
                     /gene="rpmJ"
                     /locus_tag="U2R64_000453"
     CDS             38243..38359
                     /gene="rpmJ"
                     /locus_tag="U2R64_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEM8917299.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            38377..38742
                     /gene="rpsM"
                     /locus_tag="U2R64_000454"
     CDS             38377..38742
                     /gene="rpsM"
                     /locus_tag="U2R64_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEM8917300.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            38770..39159
                     /gene="rpsK"
                     /locus_tag="U2R64_000455"
     CDS             38770..39159
                     /gene="rpsK"
                     /locus_tag="U2R64_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEM8917301.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            39239..40177
                     /locus_tag="U2R64_000456"
     CDS             39239..40177
                     /locus_tag="U2R64_000456"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEM8917302.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            40205..40585
                     /gene="rplQ"
                     /locus_tag="U2R64_000457"
     CDS             40205..40585
                     /gene="rplQ"
                     /locus_tag="U2R64_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEM8917303.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            40857..41696
                     /locus_tag="U2R64_000458"
     CDS             40857..41696
                     /locus_tag="U2R64_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8917304.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            41672..42541
                     /locus_tag="U2R64_000459"
     CDS             41672..42541
                     /locus_tag="U2R64_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8917305.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            42531..43328
                     /locus_tag="U2R64_000460"
     CDS             42531..43328
                     /locus_tag="U2R64_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEM8917306.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            43531..44277
                     /gene="truA"
                     /locus_tag="U2R64_000461"
     CDS             43531..44277
                     /gene="truA"
                     /locus_tag="U2R64_000461"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEM8917307.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(44610..47279)
                     /locus_tag="U2R64_000462"
     CDS             complement(44610..47279)
                     /locus_tag="U2R64_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEM8917308.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(47517..47705)
                     /locus_tag="U2R64_000463"
     CDS             complement(47517..47705)
                     /locus_tag="U2R64_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEM8917309.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            47975..48337
                     /locus_tag="U2R64_000464"
     CDS             47975..48337
                     /locus_tag="U2R64_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8917310.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            48389..50071
                     /locus_tag="U2R64_000465"
     CDS             48389..50071
                     /locus_tag="U2R64_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEM8917311.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            50188..52224
                     /gene="recG"
                     /locus_tag="U2R64_000466"
     CDS             50188..52224
                     /gene="recG"
                     /locus_tag="U2R64_000466"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEM8917312.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            52273..53274
                     /gene="plsX"
                     /locus_tag="U2R64_000467"
     CDS             52273..53274
                     /gene="plsX"
                     /locus_tag="U2R64_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEM8917313.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            53396..53638
                     /gene="acpP"
                     /locus_tag="U2R64_000468"
     CDS             53396..53638
                     /gene="acpP"
                     /locus_tag="U2R64_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEM8917314.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            53906..54910
                     /locus_tag="U2R64_000469"
     CDS             53906..54910
                     /locus_tag="U2R64_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917315.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            54911..55855
                     /locus_tag="U2R64_000470"
     CDS             54911..55855
                     /locus_tag="U2R64_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917316.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            55855..56817
                     /locus_tag="U2R64_000471"
     CDS             55855..56817
                     /locus_tag="U2R64_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917317.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            56844..57758
                     /locus_tag="U2R64_000472"
     CDS             56844..57758
                     /locus_tag="U2R64_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917318.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            57785..59566
                     /locus_tag="U2R64_000473"
     CDS             57785..59566
                     /locus_tag="U2R64_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917319.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            59914..60600
                     /locus_tag="U2R64_000474"
     CDS             59914..60600
                     /locus_tag="U2R64_000474"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEM8917320.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            60620..64201
                     /gene="smc"
                     /locus_tag="U2R64_000475"
     CDS             60620..64201
                     /gene="smc"
                     /locus_tag="U2R64_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEM8917321.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            64210..65019
                     /locus_tag="U2R64_000476"
     CDS             64210..65019
                     /locus_tag="U2R64_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8917322.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            65030..66028
                     /gene="ftsY"
                     /locus_tag="U2R64_000477"
     CDS             65030..66028
                     /gene="ftsY"
                     /locus_tag="U2R64_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEM8917323.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            66215..68482
                     /gene="gshAB"
                     /locus_tag="U2R64_000478"
     CDS             66215..68482
                     /gene="gshAB"
                     /locus_tag="U2R64_000478"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HEM8917324.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(68571..69023)
                     /locus_tag="U2R64_000479"
     CDS             complement(68571..69023)
                     /locus_tag="U2R64_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEM8917325.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            69173..70123
                     /locus_tag="U2R64_000480"
     CDS             69173..70123
                     /locus_tag="U2R64_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEM8917326.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            70116..71075
                     /locus_tag="U2R64_000481"
     CDS             70116..71075
                     /locus_tag="U2R64_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEM8917327.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            71072..71827
                     /locus_tag="U2R64_000482"
     CDS             71072..71827
                     /locus_tag="U2R64_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8917328.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            71850..72803
                     /locus_tag="U2R64_000483"
     CDS             71850..72803
                     /locus_tag="U2R64_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917329.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(73447..73743)
                     /locus_tag="U2R64_000484"
     CDS             complement(73447..73743)
                     /locus_tag="U2R64_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HEM8917330.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            74098..74454
                     /locus_tag="U2R64_000485"
     CDS             74098..74454
                     /locus_tag="U2R64_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEM8917331.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            74464..75363
                     /locus_tag="U2R64_000486"
     CDS             74464..75363
                     /locus_tag="U2R64_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HEM8917332.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            75880..76611
                     /locus_tag="U2R64_000487"
     CDS             75880..76611
                     /locus_tag="U2R64_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEM8917333.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            76756..78783
                     /locus_tag="U2R64_000488"
     CDS             76756..78783
                     /locus_tag="U2R64_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEM8917334.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            78891..79988
                     /locus_tag="U2R64_000489"
     CDS             78891..79988
                     /locus_tag="U2R64_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEM8917335.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            80295..>80741
                     /locus_tag="U2R64_000490"
     CDS             80295..>80741
                     /locus_tag="U2R64_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917336.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        26452 a        14500 c        17273 g        22516 t
ORIGIN      
        1 tgaatataat aacaatcaaa gagccagacg ccaagacgca gagccgataa tttgagaaat
       61 gaaactctca tcttatcggc tctttttgtt tatctgaatt ttactgacta gccttcaata
      121 tttcttgctt cattgatacc ttttgctagt gcttccatta aggatagttc tttgtctgta
      181 aagctatcca tgtatttttc tacctgtaac cttcgagtgc ttttaatcaa attatctgta
      241 ggtaagaaaa attcatcaat agatacatgg agtaatgata caagatcata cagcacttgt
      301 gtacttgggt gttgtccttt gttttctata tttgttaaat aacgtgggtc aatttcaatc
      361 attgttccca cttgttcacg agtgagaccc cgtttcattc gagcctcttt aatcgctaaa
      421 ccaacggctc taaaatcgta tttatcttct tttttacgca tactaaatca cctctataca
      481 ttttactgtt cctatataac cataaacagg tatagaaaaa catgttatat agtttatgag
      541 ttcctataga acactgtgga atttattaat gcgatgaatc caatttcaaa tagaaaggtc
      601 gctgatttta tttacctata caactttata aaatttagtc atactcctag aaagtagata
      661 aaattggcga cttaatggag ggaaaagtcg ccatgagaaa gataatctgt catctagttc
      721 tcttaattaa gttcttatca aaaaaactta tccacctgta ctggatagat atgaccatca
      781 atgtggtttt gcagattaca tagatagaaa aatcaaagca tatgaacaga gaaaacaatc
      841 tgtttatgtg cttttttggt cacttaataa atatctttta ggatttctct tcatttatgc
      901 aacaaatccc cctttcgtgt cggggtttag tatgaaggga gataaagaag cacatgccac
      961 tccctttcac gacagaaagg gggtgaaaag catgaaacca tcttcttttc aagaaaccat
     1021 agaaaatcag tttgactata tctgcaaaca agttattgaa gatgaacgaa aagattactt
     1081 caaacatcta gacagactat cagcaaaaga agtctcgttt tctgatatag ataactacct
     1141 tgtcaactct ttttctactg ttgatacgta cgtcactgat ttccaactat ttaaattatt
     1201 tggattaaga atcaatgttg aaagtgattt attaagtgaa gccctgcgtc atctttcaga
     1261 gaaaaaacgg aacattattt tacttcatta ctttatggat atgagtgatg tggagattgc
     1321 ggagttacta aatttgaatc gttcgactgt ttatcgtcat cgaataagtg gactagccat
     1381 gattaaagaa ttcatgaagg agtgtaaaga atgaaaacag cttatccaag ggttcccttc
     1441 cccctcattg taaaggcgac agatggcgac gtggaagcaa ttaatcagat tgttaaacat
     1501 tatcgagggt atacctcaaa acgttcatta cgtcgcatga cagacgaata tggaaattct
     1561 catatggtta ttgatgaaac cctacgtggc agaatggaaa cgaaactcat ctctaagatt
     1621 ttatcgttcg aaattaaata gtcccatttt ttcgtggaag cgtgtcgaat cgtatccacg
     1681 cttcccgatt tgggaggttt gttattccat caaagcatat tgtgtgttca gtaggttttg
     1741 ataggctaac aagccaaacg ttctttgaca accaaataaa ggcaatcgaa tacgtttcgg
     1801 taagaaaaga gctgatgaac taacacgcca tgacctacaa aattagtgag cgattcatgt
     1861 tagtaattcg aaagtaatct ttagcaggat tgctgccatg actttcttat cgtgataatg
     1921 atactcccgt atagccatag tccgagcgtt agaagcgtca caggcaatgg gtacggctac
     1981 atgagaacca tgcagaagtg aaattcctgt gagctttgct agagctgttc gattgctaag
     2041 atattcttct cttgtcagtg tattattata aaactatttg atataattat aggtgaatat
     2101 tggagttttc ctagcctata attgggaaag gagtaataat gataacggtc acaaaaaagg
     2161 atttagttga gctaggatat ggaacttctt tttcagcaga catcataaaa aaagcaaaag
     2221 aattgatgat tacaaaaggg catatctact atcaatctcg aaagctagat agagtccctc
     2281 gtgaagctgt tgaagaaatt ctaggaattc ggttttcaaa tgaaaacagg tctgagtagt
     2341 ttttgcacag taaggagtaa aaactatggt taaagaccca ataaaaaaag caaagaatgg
     2401 aacctattat tttcgtgcaa atctaggtta tgattctaaa gggaaaaaaa ttcaaaaata
     2461 tcgtagtgga ttcactacta aaaaagaagc aagagaagaa tattcgaaac tgctattgat
     2521 gaaaccagaa gaattaagtg agaataagga taaaatgacg tttaaacatt atatctttga
     2581 aattttcctt ccatggtata agacacaggt aaagctcaga acatatgaaa atcgcttacc
     2641 aactattaag aagcatttct cttattttga taaaatggct gtttccgata ttgagcctat
     2701 tgatgtgcaa aattggcaac taaaattatc aaagaagtgt aagtcttctt atgtaagagc
     2761 tgttcaagga ctattttcag ttgctatgga tcgagcaatt gtccttggga taaccaccac
     2821 aaatccatct aagattattg gcaatgtgaa aaagcaaaag tctaaaattg aattttggac
     2881 aaaagaagaa tttgaaaaag taatctctct aatttacaaa gaagattact atcaacactt
     2941 tttatttatc tctctgtggt ttttatttat gactggaatg cgaattggtg aagctactgc
     3001 cattcaatgg gaagatattg attttgactc aggagtacta accatcaaca aaacactcta
     3061 ttacaagaat caatcgaatt atagatttgt tgaaccaaaa acaaaggcga gcgttcgtca
     3121 tattgtatta gataaatgca cattaactta tttatccgaa tggaaggaag tacaacaaaa
     3181 tctaattcag acagactttg taatgagcta taacggtatt cctacccaaa aacatacact
     3241 atcatatgct attgaacgct atgctaagct ggctggtatc catcgaatca gaatccatgg
     3301 gttacggcat tctcatgctt ccttgttaat cagtatggga gaaaatccac ttatcattaa
     3361 agatcgtcta ggacacgaag atattgagac gactttagga acgtatggac atctttatcc
     3421 taacagtaat ttcgaggtag ctaacaaatt aaatggagcc atttccttta aagaagcaaa
     3481 acaaaattat gatacttcac caaagaatca atttactgta gactacttgc gaaacaaaga
     3541 aatgaaaaaa gtgcaataaa agtgcagtaa aaagataaga agagccagaa acccttggta
     3601 taagaggatt tctagctctc ctacaactat tcccactcca ctgttgctgg tggtttagaa
     3661 gtgatgtcat acacgatacg gttgacgtgg gctacttcgt ttacgatacg tacagagatt
     3721 ttttgcaaga cttcccatgg gatacgggca aagtcagcgg tcattccgtc gattgaagtt
     3781 acagcacgga taccgactgt gtagtcgtaa gtacgtccgt cacccataac accgacagag
     3841 cggatccctg gaagaacagt gaaatattgc cagatatcac ggtcaagtcc agcagctgcg
     3901 atttcttcac gcaagatagc atcagattcg cgtacgattt ctagcttgtc ttcagtgatt
     3961 tcgccaagaa cacgaatacc aagaccagga ccagggaatg gctgacgcca aacgattgaa
     4021 tcaggcatgc ctaactgagt ccctaattca cggacttcgt ctttgaataa tgtgtttaat
     4081 ggttcgatca attcaaattg catatcttct ggcagtccac ctacattatg gtgagatttg
     4141 atcgtctgtg ctgtttctgt accagattcg ataacgtcag tatacaacgt tccttgtgct
     4201 aggaaagaga cgccttcttc accagcaagt tttgttgctt cgtcatcaaa aacatatacg
     4261 aattcattcc caatgatttt acgtttttgt tctgggtcag atacaccttt caacttgtct
     4321 aagaagcgat ctcttgcatc gactttgatg atgttcaagc cgaattttcc gcctagactt
     4381 tccattactt gttccgcttc gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc
     4441 aattggtcac cgatcgcttt ttgtaaaaga accccaacga cactagaatc aacgccacct
     4501 gaaagaccaa gcaagacttt tttgtcacca acttgttcac ggattttttc tacttgcata
     4561 tcgataaagt tatccattgt ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg
     4621 cgcagcaatt cgattccgta ttcggaatga cgtacttctg catggaattg gataccataa
     4681 aaattacgtg ttgtgtcttg gatagaagca atcggacaat ctttgcttgt tccgactgtt
     4741 tcaaagcctt caggaacttt agttaccaag tcaccatggc tcatccatac tgtttgttgt
     4801 tttggtgttt ctttaaacaa gacagcttga tcgcttgtta cttctaacaa ggctttccca
     4861 tattcgcggt ttttagcagg ctctacggaa ccgccaagtt tgtacgtgat caattgcata
     4921 ccatagcaaa tccctaatac aggaatacct aaattgaaga tctcaggatc gatcccaaat
     4981 gcattctcat catatacact gtttggtccg ccagaaagaa tgattccctt tggattcatc
     5041 gcttttactt cttctgcagt aatgcggtgg ctcaataatt cggaaaagac tccaagatca
     5101 cgaatacgtc ttgtgatcaa ttggttatac tgactaccgt agtctaatac gataatcttt
     5161 tcaacgttcg tcatatcggc aacgtttgtc aaatttatta cccctatccc tttaaatttt
     5221 atctcaaaat agtcaaacta ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat
     5281 gatatgattt tcagttttat ggagaattat atcggctctt cctcgtgtag gcaagatata
     5341 ttcctgtaaa tttttcaaat tcacattttt ccatacatct tttgccattt taaaggcttc
     5401 ttcacgatct ccgatagcaa aacgataata ataattctct ggattttgga aagccgtatc
     5461 cagtaacgca ccaaaacgat ccaaatacca tttttcgatc agcacgggat cggcatcgac
     5521 atagacagaa aaatcaaaaa agtcgctgac gtagatttgc tgattcgcag gtaattgaag
     5581 cgtattgatc ccctcaacga tcaagatatc aggctgctgg atcaattcgt acttgtctgg
     5641 aatgatatca tacacatcat gtgagtaaac aggtactttt atctcttcct gaccagattt
     5701 tacacggttc aagaaatcga tcagcatctc catatcataa ctttcaggaa atcctttacg
     5761 gtccatgatt ccacgctctt ttaatatacg atttggataa agaaatccgt cagtcgtgat
     5821 cagctgaacg tttcttcgtt tgaaggtacg agacaaaatc gtctgcagca gtctggctgt
     5881 tgtacttttt ccaacggcta cacttccggc gatcccgata ataaaaggcg gtacttctac
     5941 gtatttatga agaaataaac ctttactcaa gaacaaagat tcaaattctt tcatataaag
     6001 ataaatcaga tgagcaagag gtacatagat atctcgaaca tcctgcatgg aaatgcggtc
     6061 attcaaactt ttgatattat ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata
     6121 aaattctcgc cattcttctc ttgccacacg gtagtagttc attggatcat tcatattagc
     6181 ctcctgcgtt ctcccatcaa tggaactatt ttaacacaaa ataaacgcaa accccaccac
     6241 ttaagagaga ttgccgatct ttttgtataa tctttataat agaaagaaac ggagtcttat
     6301 tcttgacttg cgcacggata cataaaagga tagactgttg tcatgaaaga aatgagaagg
     6361 atggaagaca tgacaaatca ttactattct gaacgcccag atacggcgca cgattttgaa
     6421 caatgggctt ttgagttaaa aggcagaacc tttcaatttg taacagattc tggtgtattt
     6481 tcacgtgaaa cagtggatta tggttcacgt gtcctgattg atgctttcga ttgggaagag
     6541 ttacctgatg aaggaaagat cttagatgtg ggatgcgggt atggaccgat tgggttagct
     6601 ttggcatttg cgacacagcg gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt
     6661 ctagcgcaag gaaacgcaaa gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat
     6721 atctatgaag cagttcatga agaaacctat gcagctatcg taagcaatcc gccgatccgt
     6781 gctggaaaaa aagttgtaca tgaaattttg acaggcgcat atcctcggtt gaagaagggc
     6841 ggtacactga caattgtgat ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg
     6901 gaagaaacat ttggtaatgc agaaatcgtc acaaaagata aaggatatta tatcatcaaa
     6961 agtgtgaaag aataactagc tgaaaaatag tggagcgacg aaagagtgga actgggcgtg
     7021 catgtacggg tacgtatcag ttcttttttt gttgagaagt ttttaaaaac aaagaactat
     7081 tttttcttca aaaagaaata gtaggaacag agtcgttgtt ttttacgata aaataaataa
     7141 gatacagaac ttgtatagaa ggctgccaag tcggtagata aaggaggttt ttatcaaaaa
     7201 acatactttc cttttttctc tattcttttc ttgggggttt tggtacactg atagggaatt
     7261 tagatagaag ggagccaata ggatgaagct gaccatcaga gatatcgcag aaatggcagg
     7321 cgtatcagta acaactgtct cacagatttt gaataacaaa ggaagcagat ttagtgataa
     7381 gacaagaaaa aaagtgttgt cgatcgtgaa tgaacatcat tataagcccg attatttcgc
     7441 ttcaaatgtg atcaatcgac attcaaagac catcggaatg atcgtccctg atgtcactga
     7501 tttcttcttc tccaaactga tcgaaggtgt agagagctat ttgaatcctt tgggctatgt
     7561 gatcatgtta tgcaattctc gtcatagcca agaaaatgag atcaagtatt tacaagagct
     7621 ttcccaccgc tcagtggacg gaatcttgct ggccacacca aatattttac ctgagaaata
     7681 tgcattagac agcggttttt atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa
     7741 tcgtcgggat aacggacggc ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc
     7801 gctgtttatt gaaaatggcc atacgaagat cggcatgctg aaggaaacca ctggatacta
     7861 tcaattagaa gaacgtttca acggatatcg tcatgcgctg aaagatcatg gcctgccttt
     7921 taatgggaaa tttgttgaac atggagagtt gactgtccaa ggtggatata ctgcatcaaa
     7981 aaaattactc aaacataaag atatcacggc tattttttgc gggaatgatg ccatggcgat
     8041 cggatgctat caggcgatcg atgaattggg caaaaaaatc ccagaagata tctcagtcat
     8101 aggattcgat ggattaaagc tgtcagaata catgattccg caattgacga cagtgcagca
     8161 gccaagtttt gatattggat tttatgctgc acgtttcctg atcgatacga tcgaatttcc
     8221 tcaaagaaaa gttccgaaca aagtgttcga aacaaaatta attattcgtg agagcgtaaa
     8281 agtattgaca aagggctaac tcggcggtat attgcttatg taagcattta caaaggctag
     8341 ttagtgcttt ttttattttt agtaaaccag tttactaaag tggtttacct ttcctaaaaa
     8401 taatgtataa taccgaatga agacaaggag gatcaggcaa tgcgaatggt ggatctgatt
     8461 gaaaaaaaga gggatggaaa cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac
     8521 tatacgaatg gaaagattcc agattatcaa gtcagtgcat tattgatggc aattttttat
     8581 caagacatga caaatgaaga aatcacgaac ttaacattgg cgattgctaa ttctggtgat
     8641 gtcatcgatt tgagttctct tgaaggaata aaggtagata agcattcgac aggtggcgtt
     8701 ggtgacacga ccacattgat tttagccccc ctagtagcta gtgtcggagt gacagtggct
     8761 aaaatgtctg gacgcggtct aggttacaca ggtggtacac tagacaagct agaagcaatt
     8821 cccggatttc agatcgagct ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa
     8881 gtagcggtaa ttggtcaatc aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg
     8941 cgtgacgtca cagcgaccgt tgattctctt ccgctgattg ccagttcgat tatgagtaaa
     9001 aaaatcgcgg caggagcaga tgcaatcgtt ttggatgtga ccactggaga cggtgctttc
     9061 atgaagaaca tcgaagatgc aagacgtctg gcaaagacca tgacgagcat tgggaaactg
     9121 gctaaccgag aaacagtggc ggttatctca gatatgtcag aacctcttgg cgaagctatc
     9181 ggaaatagtc tagaagttgt cgaggcaatc gaaacattac aaggaaatgg tccagaagat
     9241 ctagtagaaa tgtgctacgc cttaggaagc caaatggttg ttcttgctgg caaagctaag
     9301 acaaccgatg aagcaagaac gttgcttcaa gaagctctgg aatcaggtaa agcgttagca
     9361 aaattcaaag aaatgatcca aaatcaaggg ggagacccag cgatcgtgga acatccagaa
     9421 cgaattttga ctgcacgcta cacaatggag cttcctgcta aacaaagcgg agttgtgtca
     9481 aaaatcgtgg caaatgaatt aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc
     9541 aaagaagaag atattgatca cgctgttgga ttgaaactgc ataaaaaaat tggtgacact
     9601 gtgacaaaag gtgagtcact attgacgatc tatagtaacg acgaagaaat cacttctgtc
     9661 attgaattat tatataaaaa tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt
     9721 catgacatca tcacagaata aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga
     9781 aaagaaatgg aactaaaccg aatgatcgac catactattt tgaaagcaga cgcatctaaa
     9841 gaagctgtga tgcaaattat cgaagaagca aaaaaatacc atttttattc tgtctgcatc
     9901 aatccagcat gggttgcgct agcgaaagaa caattacaag gtgagccagt agccgtatgt
     9961 acagtaatcg ggtttcctct aggagcaaac acacccgaga caaaagcatt tgaaacaaca
    10021 gatgccatca ataacggtgc agatgaagtc gatatggtca tcaatatcgg tgctttgaaa
    10081 tcaaaggatg atcaacaagt ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat
    10141 cgtgcgcttg tcaaagttat tattgaaaca tcgttattag atagagaaga aatcatccga
    10201 gcttgcgaaa tagcaaaagc tgcaggcgct gattttgtca aaacatcaac tggtttctca
    10261 acaggcggag caaaggtaga ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg
    10321 ggtgtcaaag cttccggcgg tatccataac gaagaagaag caatggcaat gatcgaagct
    10381 ggtgctacaa gaatcggaac aagcgcagga gtagcaatcg tatctggttc aactggtgaa
    10441 ggctattaat tttttcaaag gagaagctca tggcagaact caaacaagaa tggatcaaca
    10501 cagctattga agcgttagat aaagcctatg ttccttattc ccattttccg gtaggcgctt
    10561 gtctcgtaac ggaatcaggc aagatttatc aaggcatcaa cattgagaat gcatcatttg
    10621 gattaacgaa ttgtgccgag cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa
    10681 catttacgca tctagtcgta gcggggcaca cccccgatcc tatctctcct tgtggtgcat
    10741 gtcgacaagt aatggcagaa ttctgttccc ctgatatgcc ggttacgcta gtaggagaca
    10801 atggtgtgac gaaggcaacg accgttcgtg cactgctgcc ttatgcattt actgaaaaag
    10861 atctataact catgttcatt cagtcagctg actgttgaaa aataaaacaa ttattttagg
    10921 aggctttaca gaaatgaaaa aagcaaaatt atttggttta ggtgctgtcg cactagcagc
    10981 agggttattt ttaggtgcat gcggcaacaa cggctctact gattcatccg gtggcaaaag
    11041 ctcatcagac acaacaactg cagcattgat cacagacaca ggtggtgtag acgaccgttc
    11101 attcaaccag tcagcttggg aaggactaga aaaatggggg aaagatcaag gactttcacg
    11161 aggaaatgat ggcttccaat atttccaatc ttcaaatgaa tcagattaca tcccaaatat
    11221 tgaccaagca ttgaatgctg gattcaaaac gatttttggt attggttata aactaaaacc
    11281 agcgatccaa gaacaagcaa caaacaatac aggtacgaac tttgttatta tcgatgatgt
    11341 catcgatgga ttagataacg ttgtatctgc aactttcaaa gacaacgaag cttcttatct
    11401 tgcaggtgtt gcagcagctt atacgactga aacaaacgta gtcggcttta tcggcggtgt
    11461 aaaaggtgaa gtaatcgatc gttttgatgc tggattcaaa gccggtgttg atgcaggtgc
    11521 gaaagaatta ggaaaagaaa tcaaagtatt gaatcaatat gctggtgact tctctgctcc
    11581 agataaagga cgttcaattg ctcaaggtat gtatgcacaa aacgcagata tcatcttcca
    11641 tgcttcaggc ggtacaggta acggtgtatt ccaagaagca aaatcattga acgaatcagg
    11701 cgacaaaaaa gtttgggtta tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac
    11761 attaaacggc gaaaagaaaa acttcacatt gacatctaca ctgaaagcag ttggaacagt
    11821 agtagaagat ttggcacaaa aatcagcgga cggtaaattc cctggcggcg aacacactgt
    11881 ttatggatta aaagaagacg gtgttggtct aacagaagga caactttctg acgaagcgaa
    11941 aaaagcagtt gatgaagcaa aagaaaaaat catttcaggt gacgtaaaag ttccagaaac
    12001 tcctgaagaa aactaaaacc atttctatag ccttgttaga cacatgtttg acaaggctat
    12061 ggtttgatta gaacaagaat tgttcattta tccaagctgc cttgtgacag tttggataag
    12121 ggaacaactc cctgaagtaa tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct
    12181 tagtcaatcg ttgccctaga tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa
    12241 atattgtcat agaaatgcag aatattacca aagaatttgg aacattcaag gcaaatgaca
    12301 acatcaattt acaagtaaag gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg
    12361 gcaaatctac attgatgaac gtgctttccg gattattaga gccgacatca gggaaaattt
    12421 tgatgcgtgg gaaagaagta aagatcacaa gtccgaccaa agccaaccaa ttagggattg
    12481 ggatggtcca tcagcacttt atgcttgttg atgcctttac tgtaacagaa aacatcgtgt
    12541 tgggaagcga gcctagtcgc gcagggatgc ttgaccataa aaaagcacga aaagagatcc
    12601 aaaaagtttc tgaacagtat ggattgtcag tcaacccaga tgcttacgtt cgtgatattt
    12661 cagttggaat ggaacaacgg gtagaaattt taaaaacact ttaccgagga gcagatgtac
    12721 tgatttttga tgagccgaca gctgtattga cccctcaaga aattgatgaa ttaatcgtga
    12781 tcatgaagga attagtcaaa gaaggcaagt cgatcatttt gattacgcat aagttagatg
    12841 aaatcaaagc agtagctgac cgctgtacag ttatccgccg tggaaaagga atcggtacag
    12901 tcaacgttaa agacgtaacc tcacaacaat tagccgatat gatggttgga agaacggttt
    12961 cattcaaaac gatgaaaaaa gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc
    13021 tagtggtgaa agaaaatcgt ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg
    13081 ctggcgaagt acttggtatc gctggaatcg atggaaacgg gcagtcggag ttgatccaag
    13141 ctttgactgg tttgcgaaag gcagaaagcg gacatatcaa gctaaaaggg gaagacatca
    13201 ctaacaaaaa accccgaaaa atcactgaac atggtgtagg acacgtgcca gaagaccgtc
    13261 ataaatacgg gttagtccta gatatgacat tatctgaaaa tatcgcacta caaacctatc
    13321 atcaaaaacc ttacagtaaa aacggcatgc tgaattattc agtaatgaat gaacatgcca
    13381 gagaattgat cgaagaatat gatgttcgaa caacgaatga acttgttccc gcaaaagctt
    13441 tatcaggcgg aaatcagcaa aaagcaatta tcgctcgtga agtcgaccga gatcctgatc
    13501 tgttgattgt tgcaaatcca actcgtggac tggatgtagg tgcgatcgaa tttattcata
    13561 aacgtctgat cgaacaaagg gacaaataca aagcagtgtt actgatcagt ttcgaattag
    13621 aagaaatttt aaatgtttcg gatcgtattg ctgttatcca tgaaggagaa attgtcggta
    13681 tcgttgatcc gaaagaaaca tctgaaaatg aattaggtct attgatggcg ggctatacct
    13741 tagaagaagc acgaaaagag ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa
    13801 aaattccgta atttattagt gcctgtactt tcagttgttt taggattgat cttaggcgcg
    13861 atattgatgg ctgcttttgg ttttcagccc atccaaggtt attcttctat gctagatgca
    13921 gcccttggtt cgcaaagagg gataggtgaa acgttaaggc aagcaacgcc gttgattttt
    13981 acagcattag gtttttctgt agctaactca gctgggtttt tcaatattgg gctttctgga
    14041 caagcacttt gcgggtggat cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca
    14101 aaagttgttt tgcttccgtt atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg
    14161 gctgttccag gtttacttcg agcatttttt ggaacaagtg aagtgatcgt aacaatcatg
    14221 atgaactata tcttattata cgtaagcaca tttgctttac atgaagtgat gcctgaaagc
    14281 tatcgctcaa gtttggactc ttccaatatg atcagtcaaa atgcctcact gcggttacca
    14341 tggttaacac aagcttttgg cggctctcgc gtaaactcag gattattttt agcaatcatc
    14401 gcgcttattt tcgtttggct gctgatgaag aaaacgactt taggatttga aatccgttct
    14461 gttggattga atccttttgc ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt
    14521 ttgtcgatgg tcatttctgg cgctttggca gggcttggcg gtgtggttga aggattagga
    14581 acgtatcaaa acttctttgt tcaaacgact tcgctatcta ttggatttga cggaatggct
    14641 gtttccttgc ttggttctgg atcagcaatc ggtattcttt tatcagcgat cttgttcagt
    14701 attttgaaga tcggtggact tggcatgcag acaggagcag gtgttccgtt tgagatcgtc
    14761 aatgtatcga ttgctttgat tatcttcttt gtcgggatca acttcctgat tcgtttcgtc
    14821 atggctaaag tcttccaagg gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa
    14881 ccaacgaatc aaaaccatga agggggcgaa ctataatgtc gactatcgaa ttaattgcct
    14941 tgatccttac ttctacactg gtttattcaa caccgctaat tctaacgtca ctaggcggaa
    15001 ctttttctga acgaagcggg atcgtaaacg tagggctaga gggaatcatg gtcatgggtg
    15061 cttttagttc catcgttttc aacttgacga tgagtccatc acttggttct atgacaccat
    15121 ggatcgctat tttagtgggt ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag
    15181 caacagtcag tttgcgtgct gaccatatta tcagcgggac agtaattaat ctgatggcac
    15241 ctgctttagg tgttttcttg atcaaagcat ggtatggtaa aggtcaaact gataacatca
    15301 cgcagaatct ggggtatttt tctttcccag gattagcaga tattccggtc attggaccaa
    15361 ttttctttaa aaatacattc ttacctgctt attgtgctat tttgattgct gtcctagctt
    15421 gggtgatcat cttcaagacg aaattcggct tgcgcctccg ttcagttggt gaaaatcctc
    15481 aagctgccga cacattaggt atcaatgtat atgctatgcg ttattcaggc gtactgattt
    15541 ctggcttgtt aggcggtatg ggcggtgctg tttttgctca gtcgatttcc ggtaactttt
    15601 cagctggtac gatcgttgga caagggttca tctccatggc tgctatgatc tttggtaagt
    15661 ggaatccttt aggggcaatg ggtgcctcat tgttctttgg ttttgctcaa agcttgagta
    15721 tcattggcgc acaattacca gttatttctt cgattccgcc agtattgctg caaattgctc
    15781 catatttgct gacaatcatt gtgctggttg ttttcttagg gaaagcttct ggtccaaaag
    15841 caaacgggaa gaactatatc aaatcaaaat aatcttttag cgaataaaaa gggtgggtta
    15901 cgggaagtgt ttttcgtctc gccctttttg ttttaaaggc aataaaaata aaaagaaaga
    15961 aggaataatc atgtttaaac gcgtacatct gatcgtcatg gattcagtag gaattggaga
    16021 agcaccagat gccgataagt tcggtgatgt tggttctgat acattaggac acattgcgaa
    16081 agaagcagga ttgaacgttc cacatttaga gcagcttggt ttaggaacga tccgtcctct
    16141 tgaaggtgtg gaatcagtga aagatcatca aggctatgcg acgaaattag aagaagtttc
    16201 tgtagggaaa gatacgatga caggccactg ggaaatcatg ggattgaata tcaaaactcc
    16261 atttcgtgtg tttcctaatg gattccctga tgatctgatc aaacaaatcg aagaattttc
    16321 tggccgtaaa gtcgtatgta acaaacctta tagcggaaca gctgttattg acgattacgg
    16381 tgaacaccaa atgaaaacag gcgatttaat tgtatatact tctgccgatc ctgtccttca
    16441 gatcgcggca catgaagaaa tcattccttt agaagaatta tatcggattt gccaattcgt
    16501 tcgtgatata acaaaagatg atccgtatat gattggccga atcattgcac gtccgtacgt
    16561 gggtgaacca ggagacttca cacgaacaag caatcgccat gattatgcgt tgaatccatt
    16621 cggacacaca gtccttgatt ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa
    16681 gatcaacgat attttcaacg gacaaggaat cactgaatct gtccgcacga aaagcaatat
    16741 ggatggcgtt gaccagctgc tgaaagttat gaaaaacgat ttttcaggaa tcagctttac
    16801 caatttagta gattttgatg cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca
    16861 tgcgattgaa gaatttgact tacgaattcc agaattgctt gaagcgatgg aagaagacga
    16921 cttgctaatg attacagccg atcacggaaa cgatccgacg tttactggta ccgatcatac
    16981 gcgagaatat gtaccgttat tggtttacag taaaaaaatg aaagaacaag gggcattgcc
    17041 tcaaggatat tattcagata tttcagcaac gattgctgag aactttagtg tttcttcgac
    17101 tgaaaatggc gaaagcttct tgaaattatt aaaataatct ttttaaatag gagaaagcaa
    17161 atgaccaagt taagcgagat gttacaagaa acgacccagt ttatccttga taaaggagta
    17221 aaagaaattg attttggttt gattctaggt tcaggattag gtgaattagc agatgaaatc
    17281 gaagatgctg taatgatttc ttatgatgag atcccgttct ttcctgtttc gacagtagtt
    17341 gggcatgcag gaaagctagt ttatgggtct ctggcaggca agaaagtgtt agccatgcaa
    17401 gggagattcc actactatga aggtcattcc atgcaaacag tgacctatcc agtacgtgtg
    17461 atggccggac taggggccca ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa
    17521 tcatttgtac caggagattt gatgctgatt accgatcata tcaattttac tggtgaaaat
    17581 cctttgatcg gtccgaatga agatgcaatg ggccctagat ttccagatat gagtcaagct
    17641 tatacgcctg actatcaagc aacagcaaaa gcagcagcag aaaaactagg tttggatctt
    17701 aaagaaggcg tatatatggg ctattctgga ccaacttatg aaacgcctgc ggagatccga
    17761 atgtctcgga caataggagc cgatgcagta gggatgtcga ctgttccaga agtcatcgta
    17821 gcagctcaca gcggattaaa agtgttagga atctcttgta ttaccaactt agcagcaggt
    17881 atgcaagcga atctgagcca tgaagaagtt gtagaaacaa ctcagagagt caaacaatct
    17941 tttaaagcat tggttaaaga aacattgaca ttattgtaat aggaggaaca ataaaatgag
    18001 tgtgcatatt gaagcgaaag aaggcgagat cgccgataag attttacttc cgggagatcc
    18061 tttgcgagct aaatatattg cggagacttt tttggaagat ccagtttgtt acaatcaggt
    18121 acgcggtatg ttaggcttta ccggcaaata taaaggagaa cgtatttctg ttcaaggaac
    18181 aggaatggga atgccatcag ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt
    18241 aaagaaattg attcgagtag gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga
    18301 tttagtacta gcacaaggtg cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc
    18361 ctttcatttt cctccaatca gtgatttcaa tctattactg aaagcatatg agatagctaa
    18421 agaaaagggc tatacggttc atgtaggaaa tgttctttcg gaagattctt tctacaaaga
    18481 tgatttgaca gagacgttcc aattagctga acttggcgtt ttaggagtgg aaatggaagc
    18541 agcggctctt tattacttag gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt
    18601 tagcgaccat ttgatcaccg gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa
    18661 tgaaatgatc gaagtaggat tggaaacagc gatagcagaa taagaaggaa atgaaaaagc
    18721 tgccctgcat taagtaataa gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg
    18781 gctggactta ttattgcaaa tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc
    18841 tgccgtttaa ctctgagtca caaggaacaa tttcaaaaaa cagcttttca tgtttgatga
    18901 atattgtgac ttgtgaccga gaagttggca ggagaaaacc gtttatacga aaaaagggac
    18961 tgtgacaaat cgtgtcacag tccctttttt atagtgtttt ttataggtag tattttttag
    19021 caactgttaa gtcatcattt aattcataaa caagtggttg acctgttgga atttcaagat
    19081 ccatgatgtc ttcgtcagag ataccttcga tatgtttagc tagggcgcgt aatgagttac
    19141 catgtgcagc tactaaaaca gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc
    19201 agaatggcaa agcgcgttct aatgtcactt tcaagttttc tccaccagga atatcgcgtt
    19261 tgtctaacat tgcgtaacga cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta
    19321 atggaggaag agtatcgtaa gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt
    19381 cagctgtttc ttttttgttc aaaccttgta atttaccata gtgacgttcg tttaagcgcc
    19441 atgatttgat ttgtggtacc caaagttgat ctgaatattc taagatcaag ttacatgttt
    19501 tgattgcacg agttaaaaca gaagtgtaag caacatcaaa ttcgattcca gcttctttga
    19561 ttttgcgtcc gccttctttt gcttcttcga ttccttctgg tgctagattt acatcagccc
    19621 aaccagtaaa ttggttcaat gcattccatt cactaagacc gtgacgagaa aaaactaatt
    19681 ttggcatgtt tagctctcct tttaagatag gtttatattt ctgaaatttt cagttctgtt
    19741 ttattgtaca attttttgga agagatttcc atcgaaaaat tagataagat tctatgagaa
    19801 aacaagtaga gaatataaaa aaacgaacag tgcccacgca actgttcgtt tttaggtatt
    19861 agatgcataa ttgctcgatt tctttttcag gtaaattgat atatttataa catgttccaa
    19921 ctgaaacacc gcattttgaa gaaataaatt ggatcgtttc ttttttttca taatagagac
    19981 gtcggatttt tttgatcgtt tttgcatcga tttttggtct tccgccgatt tttccttttt
    20041 tacgagcttc atctaatcca actaatgtac gttctttgat caatgcgcac tccatgtttg
    20101 ctaggttttc cattaattgg aaatagattt ttcccatttc gcgcgtatcg attccttcat
    20161 caagactaat caagtgcagc ccgcgatctt tgaataattg cgtgagttct gttaattgcc
    20221 gcgtagattt gcctaatcga tgaagttggc aaatgactag tgcatcgcct tgttgcatgt
    20281 cagcgatcac tgactccaaa tgaacagcag tagaatcatt ttgttccact tcatatgtct
    20341 catggaaaat ttcttgacaa ccaaagtcag ataattgatc aacctgagtt gttaaatcaa
    20401 cgtcatttat ggttgtgcgt gcataaccaa taattttcat ggtgattcct ttctagcagt
    20461 gattttctaa ctggatataa cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt
    20521 tttcgcaaat tttccgctgt ctttttttat tggatgatca agcagttttt ctttatttac
    20581 gacggattgc gtcaagaatc tcaacgcctt tttctgagcc gacaactact ttagaaacca
    20641 tgtttaggaa aagcccatgt tctactaccc caacaagttc atctaaatag gtagctaagc
    20701 tttctggctg ttcgatgact tctagatgca gatcaatgat gtaatgacca ccatctgtgg
    20761 ttaagacttc tccgttttcg tctgtacgca agacgggttg gaatcttttt tcttcaaaaa
    20821 tatgaagtag ctgttgggag ccataaggga tcacttcaac tgggagtggg aacttcccaa
    20881 gtttatcgac taatttagaa gaatcaacga tccaaatcgt ttcttttgag tacgtagcga
    20941 ctattttctc gaaaagcaaa gcagcgccgc cgcctttgat cccttgaaaa tcagcactga
    21001 tttcatcagc accgtctatt gtcaaatcga ctacggggac ttcatcaata ctctttaacg
    21061 gtattcctaa tttttccgct tgttcttttg tcgcatttga agtagtaact cctgtgatac
    21121 gtaaaccttc ttcacgcata cggcgaccaa tctcttctac catataatag gcggttgaac
    21181 cggtcccgag acctacgatc atcccgtcct ttacgaattt cgcggcttca atgccagcta
    21241 attgttttaa attcatcttt gcgtccacct ttttttagtt tgagcatcgt gctttcctca
    21301 ctattttagc gtgatttacg gtaaaaagat accattcttt tttattccaa taaagctttt
    21361 tcaaaaaaaa ttgcatctct tgttgacatg ttttttcatt cgtgatattc taacaaaggt
    21421 gctttatcta caggtttctg tgaagaaacg tgctgactgt ttatcaaagc atatttgata
    21481 aggatgcaga cattgcattt attttttatc acaaaaaaag aaccacctgg atgtgtggaa
    21541 ctagacgcaa atcgtgggaa ggaggaaaca aggaatgcct acaattaacc aattagtacg
    21601 taaacctcgt aaatcaaagg tggaaaaatc taattcacct gctttgaaca aaggatataa
    21661 cagctttaag aaaactcaaa ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg
    21721 tgtgggtaca atgacaccta aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg
    21781 tttgtcaaac ttaattgaag ttactgctta tatcccaggg attggtcata acttacaaga
    21841 acacagtgtt gtattattac gcggtggtcg tgtaaaagac ttaccagggg tacgttacca
    21901 tatcgttcgc ggtgctttag atactgctgg tgttaacgac cgtaaacaaa gccgttctaa
    21961 atacggaact aaaaaaccta aagcttaatt ttaattatta aacaaatgaa acttgcttct
    22021 actatataga agtaattact atgaacaata tttcggaagg aggagttacg gatgccacgt
    22081 aaaggtcctg ttgcaaaacg tgatgtttta ccagatccta tttataactc aaaattagta
    22141 actcgcttga tcaaccgtgt aatggttgac ggaaaacgcg ggattgcagc taacattatc
    22201 tataatgcct ttgacttgat caaagaatct acaggtaacg atccattaga agtgtttgaa
    22261 caagcaatga aaaacgttca acctgttctt gaagttaaag cacgtcgtgt tgggggttca
    22321 aactaccaag taccagttga agttcgccct gaacgccgcg ttactctagg tcttcgttgg
    22381 gtagtaaact acgctcgctt gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa
    22441 atcatggatg ctgcaaacaa cacaggtgct tctgttaaaa aacgtgaaga cactcataaa
    22501 atggctgatg ccaaccgtgc gtttgctcac tatcgctggt aagattctct ctgtttggtc
    22561 ggcttttata agtcgacctc agatagtgtc cttattttta gcaactagat agtaaagaga
    22621 ggagaaacaa ggagaatgac cagagaattt tctttacaaa acactcgtaa tatcggtatc
    22681 atggcccaca tcgatgctgg taaaacgact gctactgaac gtatcttgta ctatactggt
    22741 aaaatccata aaattggtga aactcatgaa ggagcttcac aaatggactg gatggaacaa
    22801 gaacaagaac gtggtattac gatcacttct gctgctacta cagcacaatg gaagggtcac
    22861 cgaatcaaca tcatcgacac accaggacac gtagacttca cagttgaagt tgaacgttca
    22921 ttgcgtgtac ttgatggtgc tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa
    22981 actgaaacag tttggcgtca agcaacaact tatggtgtac ctcgtatcgt atttgcaaac
    23041 aaaatggaca agatcggtgc tgacttctta tattcagtat caactttaca tgaccgtttg
    23101 caagcaaacg ctcacccaat ccaattacca attggtgcgg aagacgactt cacaggaatt
    23161 atcgaccttg taacaatgaa ggctgaaatg tatacaaacg atcttggaac agagatcgaa
    23221 gaaacagaaa ttcctgaaga ataccgcgaa ttagctgaag aatggcgcga aaaattggtt
    23281 gaagctgtag ctgaaactga tgaagaactt actttgaaat acttagaagg tgaagaaatc
    23341 actgaagctg agttaaaaga aggtatccgc cgcgcaacag ttaacgtaga attctaccca
    23401 gtactatgtg gttcagcatt taagaacaaa ggggttcaat tactattgga cgctgttctt
    23461 gattacttgc catcaccgtt agatatccca gctatcaaag ggattgaccc taaaactgat
    23521 gaagaagtag aacgtcctgc agacgacagc gctcctttct cagctttagc atttaaagtt
    23581 atgactgacc cattcgtagg tcgtttaact ttcttccgtg tgtactctgg tgttttacaa
    23641 tcaggttcat acgtacaaaa cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta
    23701 cagatgcatg ccaactctcg ttcagaaatc tctgaagttt acgctggaga tatcgctgct
    23761 gctgttggtt tgaaagacac aactactggg gacacactat gtgatgaaaa gagtctagtt
    23821 attcttgaat ccatggaatt cccagaacca gttatccaag tcgctattga acctaaatca
    23881 aaagctgacc aagataaaat gggtgtggct ttacaaaaac tatctgaaga agatcctact
    23941 ttccgtgctg aaacaaacgt ggaaacaggc gaaacaatca tcgctggtat gggtgaactt
    24001 cacttagata tcatcgttga ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt
    24061 gcgcctcaag tatcttaccg tgaaactttc cgtgctggca ctcaagccga aggtaagttt
    24121 gtacgtcagt ctggtggtaa aggtcaatac ggtcacgtat ggattgaatt tacaccaaat
    24181 gaagaaggtg ctggtttcga atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa
    24241 tacattccag ctgttgaaac tggtttgaaa gatgctatgg aaaatggtgt cttagctggc
    24301 tatccattag tagatatcaa agctaaactt tacgatggtt cataccatga tgtcgattca
    24361 aatgaaactg ccttccgtgt tgctgcttct atggcattac gtgcagcagc taagaaagct
    24421 aatccagtaa tccttgaacc aatcatggct gtagaagttg ttatccctga agattattta
    24481 ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc
    24541 gctggcggcc aacaagttgt tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct
    24601 acaactcttc gttctgctac tcaaggtcgt ggtacattta caatgacatt tgaccactac
    24661 gaagatgtac caaaatcagt acaagaagaa atcattaaga aaaacggcgg aaaagctgaa
    24721 taatttctta aaaccggata gtcctgcaaa gagattatcc aaagagacta tatttttaat
    24781 atagtttcgt gtaaaataat tatcgatgat atgggcatgt ggtgtacctt gtgtacatca
    24841 tatacctatc agacaaataa aaaatatatt gtatttttag gaggacattt taaaatggca
    24901 aaagaaaaat ttgaccgttc taaaccacac gttaacattg gtactatcgg acacgttgac
    24961 catggtaaaa ctacattaac agctgcaatc acaactgtac tatctaagaa aaacggcggc
    25021 caagctatgg cttacgatca aatcgatggt gctccagaag aacgcgaacg cggaatcaca
    25081 atctcaacag ctcacgttga gtatgaaaca gatacacgcc actacgctca cgttgactgc
    25141 ccaggacacg cggattacgt taaaaacatg atcactggtg ctgctcaaat ggacggagct
    25201 atcttggtag tttctgctgc tgacggccca atgcctcaaa ctcgtgaaca catcctattg
    25261 tctcgtcaag ttggtgttcc ttacatcgtt gtattcttga acaaagtaga catggttgat
    25321 gacgaagaat tactagaatt agttgaaatg gaagttcgtg acctattaac agaatacgaa
    25381 ttccctggtg acgatgttcc tgtagttgct ggatcagctt tgaaagctct agaaggcgac
    25441 gcttcatacg aagaaaaaat tcttgaatta atggctgcag ttgacgaata catcccaact
    25501 ccagaacgtg acaacgacaa accattcatg atgccagttg aagacgtgtt ctcaattact
    25561 ggacgtggta ctgttgctac aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa
    25621 gttgaagttg ttggtattgc tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg
    25681 ttccgtaaat tgttagacta cgctgaagct ggagacaaca ttggtgcttt actacgtggt
    25741 gttgcacgtg aagacatcca acgtggacaa gttttagcta aaccaggtac aatcacacct
    25801 catacaaaat tctctgcaga agtatacgtg ttgacaaaag aagaaggtgg acgtcatact
    25861 ccattcttca ctaactaccg tccacaattc tacttccgta caactgacgt aacaggtgtt
    25921 gttgaattac cagaaggaac tgaaatggtt atgcctggcg acaacgtaac aatggaagtt
    25981 gaattaatcc acccaatcgc tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga
    26041 cgtacagttg gtgccggtgt cgttacagaa atcaaagctt aattcactta agttttaaag
    26101 taaagcaaca tttattcgga cgtaatcgct cggaacgaag gtcttaggat ctttgttccg
    26161 agctttttta tttattgcag gatcaggaaa aaagacagga gtattataaa tagaagaaac
    26221 acgaaataaa agagtcagta ttttctaaat gaaactttat gaaaacaaaa tgttttttac
    26281 aagaaaaagc cttgctttgt gagtttatat atattataat gacaaaggtg cgtttacttt
    26341 agtgaattgc acagacgtaa tcagaatgat ttcgtcggct aagaaacgag aggttgcgac
    26401 acgcccggac gctttgccac gaacgagcgt gacggaaatt ttcgtggagc tatgtctact
    26461 tttcaaaata ggcgaaggag ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa
    26521 agcgtatgaa caccgtattt tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag
    26581 aactggagct agcgtgtctg gtccaattcc attaccaact gaacgcagtc tttacacaat
    26641 catccgtgcg actcataaat acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa
    26701 acgtcttatc gacattgtga acccaacacc aaaaactgtt gatgctttga tgaagctaga
    26761 cttaccatct ggtgtaaaca tcgaaatcaa attataaaac taaaacaaaa ataatggagg
    26821 tgtactcatg accaaaggaa tcttagggaa aaaagtggga atgacacaaa tcttcactga
    26881 atctggtgaa ttaattccag taactgttgt agaagctact ccaaacgtag tactacaagt
    26941 gaaaacaatg gaaacggatg gctacgaagc tattcaagtt ggttaccaag atatgcgtga
    27001 agttttatca aacaaacctg cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg
    27061 cttcattcgt gaattcaaaa atgttgagct aggagaatat gaagtaggaa aagaaattac
    27121 agtagatgtt ttccaagcag gagacattat tgatgtaaca ggtactacga aaggtaaagg
    27181 attccaaggg gttatcaaac gccacggaca aagccgcgga ccaatggctc acggttctcg
    27241 ttaccatcgt cgtcctgggt caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa
    27301 acgtcttgct ggccgtatgg gtggcaaccg cgtaactatc caaaacttgg aagttgtacg
    27361 tgtcgatgca gaaagaaatg ttatcttgat caaaggtaat gttcctggag ctaaaaaatc
    27421 tttaattact atcaaatcag ctgtgaaagc taaataattg taggaagaaa ggaggaacta
    27481 aggaatgccg aatgtagcat tattcaaaca agatggaagc caaaacggtg aaatcacact
    27541 taacgaagaa atcttcggaa ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat
    27601 gcaacgtgcg tcattaagac aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg
    27661 cggcggacgt aaaccatggc gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg
    27721 ctcaccacaa tggcgtggag gtggcgtagt ctttggacca acaccacgtt cttacagcta
    27781 caaacttcct aaaaaagttc gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc
    27841 tgaaaacaac ttggtagcaa tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt
    27901 caaacaagtt cttgctaact tatctatcga ctctaaagta ttggttgttc tagaaaaagg
    27961 taacgacttt gctgctttat cagcacgtaa cttaccaaac gtttctgtag taacttctga
    28021 taatgtgagt gtgctagacg ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct
    28081 tactcaaatt gaggaggtgc ttgcataatg aacttactag acgtaatcaa acgcccagtg
    28141 atcactgaaa aatcaatgct tgccatggat gacaagaaat acacttttga agtggacact
    28201 cgcgcaaaca aaactttagt aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa
    28261 aacgtgaaca tcgtgaacgt acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat
    28321 acaaaaaaac gtcgcaaagc gatcgttaca ttgactgaag attcaaaaga aatccaatta
    28381 ttcgaagctg ctgaataagc actaatagat aactcattaa attaggaggg aaaaacgtgg
    28441 cgattaaaaa gtacaaacct acctcaaatg gtcgtcgtaa catgacaggt tctgattttg
    28501 ctgaaatcac aacatcaaca cctgaaaaat cattgttaca accattgaaa aaccatgctg
    28561 gacgtaacaa caacggccgc atcactgtac gtcatcaagg tggcggacac aaacgccaat
    28621 atcgcgtgat cgacttcaaa cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg
    28681 aatatgatcc aaaccgttca gctaacatcg cgttagtaca ctatgaagat ggagtgaaag
    28741 cttacatctt agcacctaaa ggactagaag tgggtatgaa acttgtttca ggtccagaag
    28801 cagatatcaa agtcggaaat gctcttccat tagaaaacat tccagttggt actgttatcc
    28861 acaacattga aatgaaacct ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg
    28921 ctcaagtact tggtaaagaa ggcaaatacg tattgatccg cttgaactct ggtgaagttc
    28981 gtatgatctt agctgcatgc cgtgctacaa tcggttctgt aggtaacgaa caacacgaat
    29041 taatcaacat cggtaaagct ggacgctctc gttggatgcg taaacgccca actgtacgtg
    29101 gtagcgtaat gaaccctaat gatcacccac acggtggtgg tgaaggtaaa gctcctatcg
    29161 gacgtaaagc accagtttct ccttggggtc aaccagctct tggttacaaa actcgtaaca
    29221 aaaaagctaa atcagacaaa cttattgttc gtcgtcgcaa aaataaataa ttactttgac
    29281 catgtgtcgc acattttgag aggaggttca ccatgggtcg tagtttaaag aaaggacctt
    29341 ttgtcgatga gcatttaatg aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag
    29401 ttatcaaaac ttggtcacgc cgttcaacag ttttcccaag ttttgttgga tataccatcg
    29461 cagtttatga tggacgtaaa catgtaccag tttacatcca agaagacatg gtaggacaca
    29521 aattaggtga atttgcacct acaagaactt atcgtggaca tgctgctgac gataagaaaa
    29581 cgaaacgcta atttgagggg aggataaatc caaatggcag aacaaatcac atcagctaaa
    29641 gcaactgcaa aaacagttcg cacttcacct cgaaaagccc gtttagtaat tgaccttatc
    29701 agaggtaaaa gtgtcgcaga tgcaatttca atcttgaaat tcacaccaaa caaatctgct
    29761 ggaatcattg aaaaagtatt gatgtcagca gttgcgaatg cagaaaataa ctttgactta
    29821 gatgttgaaa acttggtagt aagcgaagct tttgttaacg aaggacctac aatgaaacgt
    29881 ttccgtcctc gtgcaaaagg atcagcttct ccaatcaaca aacgtacaag tcatatcacg
    29941 gtagtcgtat cagaaaaata aggagggata atcagtgggt caaaaagtac atccaattgg
    30001 aatgcgtgta ggcatcatcc gcgactggga tgctaaatgg tatgctgaaa aagagtatgc
    30061 tgagttctta cacgaagatt taagaatccg taaatttatt tcaactaaac ttgctgatgc
    30121 tgctgtatca acagttgaaa tcgaacgcgc aacaggtcgc gtaaacattt caattcacac
    30181 agctaaacca ggtatggtta ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga
    30241 attaaacaaa ttaactggta aaagaatcca tatcaatatc gtggaaatca aaaaaccaga
    30301 tctagatgca aaattagtag gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt
    30361 ccgtcgcgct caaaaacaag ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa
    30421 aactcaagta tctggtcgtc taaacggagc agatatcgct cgttcagaag gatactcaga
    30481 aggaactgtt cctcttcata ctttacgtgc ggacattgat tacgcatggg aagaagcaga
    30541 tacaacatac ggaaaactag gagttaaagt gtggatctat cgtggagaaa ttcttccaac
    30601 taaaaaaaac actgagaaag gagggaaata atcatgttag tacctaaacg tgtaaaacac
    30661 cgtcgtgaat tccgcggaaa aatgcgcggg gaagctaaag gcggaaaaga agtagcattc
    30721 ggtgaatacg gtttgcaagc tgttgattca cattggatca caaaccgcca aatcgaagct
    30781 gctcgtatcg caatgactcg ttacatgaaa cgtggtggga aagtatggat taaaattttc
    30841 cctcacaaat cttatactgc caaagcaatt ggggtacgta tgggttctgg taaaggggca
    30901 cctgaaggat gggttgcacc agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt
    30961 cctgaagaag tagctcgtga agcgttacgt ctagcttctc acaaattacc aatgaaaact
    31021 aagatcgtaa aacgtgagga aatgggtggt gaatcgaatg aaggttaaag aaatcagaga
    31081 attaaccact gccgaaatgc ttgatcaaga aaaacaatta aaagaagaat tgtttaatct
    31141 tagattccaa ttagcaacag gtcaattaga aaacactgca cgtattaaag aagtacgtaa
    31201 atcgattgca cgcatcaaaa ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc
    31261 cattaagcgt atgactgaag gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc
    31321 agacaaaatg gataaaacaa ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta
    31381 tggcaaacgc atgaactatt ctaagaaata caaagtgcat gatgaaaaca acacagcaaa
    31441 agttggcgac atcgtgagaa ttatggaaac tcgtccatta tcagctacaa aacgtttccg
    31501 tttgttggaa gtagtcgaag aagcagttat tatctaataa cacgagattt tcctatatag
    31561 attgaatgca aaatctgaaa ggaggataca caacgtgatc caagcagaaa gtcgtttaaa
    31621 agtcgctgat aactcaggcg cacgtgaaat tttgacgatc aaagtccttg gtggatctgg
    31681 tcgtaaaact gctaacatcg gtgatgtgat cgttgctacg gttaaacaag caacgccagg
    31741 tggggttgtc aaaaaaggtg acgtcgttaa agccgttatc gttcgaacaa aatcaggagc
    31801 tcgtcgtaca gacggttcat atattaaatt tgatgaaaat gctgcagtga ttattcgtga
    31861 tgataaaagc cctcgtggaa cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa
    31921 caacttcatg aagatcgttt cactagcacc agaagtttta taatcttgag acacttatca
    31981 aaggaggtgc gaaacagtta tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg
    32041 aaaagacaaa aacaaagaag gcgttgtact agcagcgttc ccgaaaaaag ataaagttat
    32101 tgtcgaaggt gtaaatgtcg ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg
    32161 tggaattgtt gagatggaag cgccaattca tgtttctaac gtgatggtgg ttgactctac
    32221 tggtgtagct ggccgagttg gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa
    32281 aaaaaccggt gaagttttag ataaataaaa gtttaaggaa ggagggtctt actgaatgaa
    32341 ccgcctaaaa gaaaaatatc ttaaagaagt aactccatca ttgatggaaa aatttaacta
    32401 tagctctgtt atgcaaacac ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga
    32461 tgcggtatca aacgctaaaa acttagataa agcagttgaa gaattaactt tgatcactgg
    32521 tcaaaaacca atgattacaa aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg
    32581 aatgccaatt ggtgcaaaag ttacattgcg cggagaaaga atgtacgaat tcttagacaa
    32641 attggtttct gtttcactac cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt
    32701 tgacggtcgt ggaaactata ctttaggtat taaagaacaa ttgatcttcc cagaagtaga
    32761 ttatgattta gtagataaag tacgtggtat ggacatcgtt attgtaacaa cagcaaactc
    32821 tgatgaagaa tctcgtgagt tgttgacaca attaggcatg ccattccaaa aataattaaa
    32881 ggaggcgaac tacgtggcta aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt
    32941 ttcaacacaa gcttatactc gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa
    33001 gttccatctt tgccgtattt gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt
    33061 gaagaaagct agctggtaaa aagtaaattc gcataagaag gaggtaaaag atcaatggtc
    33121 atgacagatc caattgcaga ttttctaact cgtatccgta acgcaaacat ggttaaacat
    33181 gagtctttag aagtacctgc atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt
    33241 gaaggtttcg ttcgtgatgt tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt
    33301 ttcctaaaat ttggtaaaaa cggcgaacgt gttatcacaa acttaaaacg tatctctaaa
    33361 ccaggtttgc gtgcttatgt caaagctgac gaagtaccaa aagtattgaa cggtttaggt
    33421 atcgcaatca tttcgacttc tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat
    33481 atcggcggcg aagttatcgc ttacgtatgg taatcaagta gaatctacaa ggaggtgtct
    33541 ttaagtgagc cgtatcggaa ataaagtcgt tgttatccct gaaggagtaa cagttactca
    33601 agacggaaac aacgttacag ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc
    33661 agatatcaaa atgaatatcg aaggaaacga agtaactttc actcgtccaa acgacagtaa
    33721 agaaatgaaa acaattcatg gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt
    33781 cagcgaaggt ttccaaaaag cgttagaact aatcggggtt gggtaccgtg cacaattaca
    33841 aggatcaaaa cttgtattga acgttggtta ctcacatcca gtagaaatca caccaccagc
    33901 tggagtaact gttgaagtac cagctaacac acaagtaatt gttaaaggtg cgaacaaaga
    33961 agaagttggc gaattagctg caaacattcg tggaactcgt cctccagaac cttataaagg
    34021 taaaggtatt cgttatgttg gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata
    34081 atcgtttaga aaaattgcat agaagccagc agcaggaaaa aggcatttgg ctgaagttta
    34141 ccttcaaaaa aatacatttt tacttgtgcc gcagcttcta tttttcgaaa cgtatttact
    34201 gcttgaaata gtagtacaat aaaaataaag aggtgacaat tgtgattaca aaaccagata
    34261 agaacaaaac acgtcaaaag agacatcgtc gtgtacgtaa caatatctct ggtactgctg
    34321 agcgcccacg cttgaacgtt tttcgttcta acaaaaacat ctacgctcaa attattgatg
    34381 acgtagcggg tgtaacgcta gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa
    34441 caaaaacaga agcagcacaa gctgtcggta aactagttgc tgaacgtgca gctgaaaaag
    34501 gcattaaagt agtagtcttt gaccgtggtg gataccttta ccatggccgt gtgcaagctt
    34561 tagctgaagc tgctcgcgaa aatggactag aattttagaa gaaggaggaa taccattcat
    34621 ggtttatatc gatccaaaac atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt
    34681 aacaaaagtt gttaaaggtg gacgtcgtct acgttttgct gctttagttg ttgtcggtga
    34741 caaaaacgga cacgtagggt ttggtacagg taaagctcaa gaagttcctg aagcaatccg
    34801 taaagcaatt gaagatgcga agaaaaactt agttgaagta cctatggttg gttcaacaat
    34861 cccacacgaa gtaatcggtg cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga
    34921 aggttctggg gttgctgctg gtggaccagt tcgtgccgta ttagaattag ctggggtagc
    34981 agatatcact tctaaatctt taggctcaaa tacaccaatc aacgttgttc gcgcaacagt
    35041 tgaaggtttg aaacaattga aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt
    35101 tgaagaatta atcggataag gaggacaaca ataatggctg aattaaaagt tactttaaaa
    35161 cgcagtatta tcggacgtcc tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca
    35221 aagattaaca gttcagtggt taagccttct aatgaagcaa ttaaaggcat gatcaatact
    35281 gtttctcacc tagtggacgt tgaagaaatt taatttagaa aaatcataac tagaacatta
    35341 aggaggtgcc aaacctatga aacttcatga attaaaacct gctgaaggtt cacgccaagt
    35401 acgtaaccgt gttggtcgtg gtacttcatc tggtaacgga aaaactgccg gacgcggaca
    35461 aaaaggacaa aaagctcgtt caggcggcgg tgtgcgttta ggatttgaag ggggacaaac
    35521 accattgttc cgtcgtttac caaaacgagg attcacaaac gtgaaccgta aagactatgc
    35581 agtcattaat cttgatgtat tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc
    35641 tttagttgaa gctggaatcg tgaaaaacga aaaagctgga atcaaagtat tagctaatgg
    35701 ggaactaaac aagaaattaa ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc
    35761 aattgaagcg gctggtggat caatcgaggt gatctaatgt ttagactatt aaaagatgct
    35821 tttaaagtaa aagacattag atcgaaaatc ctatttactg tatttgtgtt gtttgtattt
    35881 cgcctaggtg cacatattac tgtaccaggc gtaaatgctg cttcattgca aaacctttct
    35941 tctttgccat ttttcaacat gttgaacttg gtaagtggta gtgcgatgca aaacttttcc
    36001 attttctcaa tgggggtttc accatacatt actgcttcta tcgtcattca gcttcttcaa
    36061 atggacatcg tgcctcgatt tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa
    36121 ctgaatcaag cgactcgata tctgacatta gtattggcat ttatccaatc tgtcggtatc
    36181 actgctggat tcaatcaata cgctcaatta ggtttcgtga ataatcctaa cgtagcaact
    36241 tacgtaacga tcggtttgat tctaacagcc ggtacgatgt ttgttacttg gctaggagaa
    36301 cagatcacag aaaaaggtat cggaaatggc gtatcaatga tcatttttgc aggtatcatt
    36361 tctagattgc ctgaaagtat cagagaaatt tatgaagatt actttataaa tattgatcct
    36421 tcagacatat ggaaatctgc tatttttgtg gccattttac tagtagcggt cttgttgatc
    36481 gtgacattcg taacattttt ccaacaagct gaacgcaaga tcccgatcca atatacgaaa
    36541 cgcgtagctg gcgcgcctac aagcagctat ctgccgttga aagtaaatgc agctggagtt
    36601 attccagtta tctttgctag ttcgtttatt gctacgccaa atgctgtttt acaagcattg
    36661 agcggtagat tcggttctga aaactggtac aaagtgatga tggagatctt taactataat
    36721 acagcacctg gtgctacgat ttatacgatt ctgatcgttg ccttcacttt cttctacgcc
    36781 tttgttcaag taaaccctga gaaattagcg gaaaacttgc aaaagcaagg aagttatata
    36841 ccaagcgtac gccctggtaa ggggactgaa gagtatgtct caagattact gatgcgttta
    36901 agtacagttg gtgcagtctt ccttggttta gtggcattgc ttccaatcat tgctcaaatg
    36961 gtttgggatc ttccacaatc aatcggatta ggcggtacaa gcttactgat cgttatcggt
    37021 gtagctttag aaactgcgaa acagttagaa ggcttaatgc tgaaacgtaa atatgttgga
    37081 ttcattgagt aagaaagcgt gttgaggttt cccctcaaca cacgttctca cacatttatt
    37141 aggagggaaa acaatgaacc tcattttaat ggggctgcca ggcgcaggta aaggaacaca
    37201 agctgaaaaa atcattgatg cttatggtat tccgcacatc tcaacaggag atatgttccg
    37261 cgcagcgatg caaaacgaaa cagctcttgg cctggaagca aagtcttata tggataaagg
    37321 tgcattagtt cctgatgaag taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga
    37381 tacagagaaa ggcttcttat tagatggctt tccacgtacg ctagatcaag caaaagctct
    37441 ggacgcaatg ctaaaagatt tgaataaaaa aattgatgct gtcatcgata tccatgttgg
    37501 tgaagaaatc ttggtcgaac gtctagccgg ccgatttatc tgcagcaatt gtggagcaac
    37561 ttaccataaa attttcaacc ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca
    37621 tgaattctat caaagagaag atgataaacc tgagacggtt aaaaatcgtc tggctatcaa
    37681 catcaaaaat agtgaaccaa tcttggctta ttataaagaa caaggtttgc taaacactat
    37741 tgatggtgct cgtgaaatcg atgctgtatt tgcagatgta caaaaaatca ttgaaaaata
    37801 gcacgattgc ccgtagccga cttgcattat gcagttactc ttgtcaagtt caataaatta
    37861 tgatagaata tgtcagtccg acttctagag aatcctctag atgatccatt ttgagaattt
    37921 tgaggtggga actgcagttt ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg
    37981 aggtactgtg cgtggcaaaa gaagatatga ttgaagtcga aggtacagtc gtcgaaactt
    38041 tgccgaatgc aatgtttaaa gttgaactag aaaacggaca ccaagttctt gctactgttt
    38101 caggtaaaat tcgtatgcat tacatccgta tcttacctgg tgacaaagta acggttgaat
    38161 tgtctccata cgatcttaac cgtggccgta ttacttatcg ctttaaataa ttgtactccg
    38221 taaaactaca ggaggtatta tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca
    38281 ttgtaaagta attcgtcgta aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca
    38341 taaacaacgt caaggataat tggaggtgct ataaatatgg ctcgtattgc aggagtagat
    38401 attcctcgtg ataaacgtgt agtagtttca cttacttata tctatggtat tggtaacact
    38461 actgctaaaa agatcttagc tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta
    38521 acgaatgaac aaacagatgc tatccgtgca gaagtagata aattaaaagt tgaaggggat
    38581 cttcgtcgtg aagtgaactt gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga
    38641 atccgtcatc gccgtggatt gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact
    38701 cgtaaaggcc cagctcgcgc tatcgctggc aagaaaaaat aattcttaag tgaaggaggt
    38761 taaaacttca tggcagcaaa aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa
    38821 gcaggtattg cacatatcca ttctacattc aataacacta tcatcatgat cactgatact
    38881 cacggaaatg cattagcgtg gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa
    38941 tcaactcctt ttgccgctca aatggcagca gaaactgcta caaaagcagc aatggaacac
    39001 ggattaaaga ctgttgaagt aacagttaaa ggacctggtt ctggacgtga agcagcaatt
    39061 cgttcattac aagctacagg tttagaagtg actgcaattc gtgacgtgac tccagttcct
    39121 cataatggtg cccgccctcc aaaacgccgt cgtgtttaat gagtgccgct cattttgagt
    39181 tttatcagta acgtcattga acaagacact tttcgttttg aaaggggtaa agataagaat
    39241 gattgagttc gaaaaaccaa gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt
    39301 catcgttgaa cctcttgaaa gagggtatgg gactacttta gggaattccc tacgtcgtat
    39361 tttattatct tctttgccag gtgctgccat cactaatatt caaatcgatg gtgtactgca
    39421 tgaattctct accatcaaag gtgttagaga agacgtcact caaatcatct tgaacattaa
    39481 aggcttagcg ctgaaaatgt atggccaaga agaaaaaacc cttgaaatcg atattaccgg
    39541 acctgctaca gtaactgctg gcgatattat cgttgatagt gatgtagaaa ttcttaacaa
    39601 agatatgtac atctgtagtg tctctgaagg agctacgttc catgctcgct taacagtgaa
    39661 acctggacgt ggttatgttc aagcagatga aaataaaaaa gaagatatgc caattggcgt
    39721 tcttccagtc gattcaatct acacacctgt tcgtcgtgtg aactatcaag ttgagaacac
    39781 acgtgttgga caccgtgaag attttgataa attgacgatg gagatttgga cagatggttc
    39841 aattgaaccg ttggaagcaa tgagtttgtc tgcgaaaatc atgactgaac atttggatat
    39901 ttttgtgaac ttaactgatg aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac
    39961 acaaaaagaa aaaatgttgg aaatgacgat cgaagagtta gacttgtctg ttcgctctta
    40021 caattgtttg aaacgtgcag gaatcaatac tgtacaagaa cttacaaata aatctgagcc
    40081 tgaaatgatc aaagtccgta acttaggacg taaatcatta gaagaagtta aagcaaaatt
    40141 gcacgactta ggtttaggtt tacgtaaaga agattaaaac cttttacgaa ggagggaaac
    40201 caacgtgagt tatcgtaaac taggacgcac atctagccaa cgtaaagcga tgttgcgtga
    40261 tttaacaact gatttattaa tcaacgaacg tattgtgact actgaagctc gtgcgaaaga
    40321 agttcgctca actgcagaaa aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg
    40381 tcgtcaagct gcggctttcg tacgtaatga agttgccagc gtgcgtgaag aaaatgagga
    40441 catcgtcatt gaatcagctt tacaaaaact gttcaacgat attgcacctc gttacgcaga
    40501 acgtcaaggc ggatacacac gcattttgaa gacagaacca agacgcggtg atggtgcacc
    40561 aatggttgtc ttagaacttg tctaaaatca cactaataac atcactttat agatgattct
    40621 tttagagtgt tatgatgttg gaagatattt ttccgagtct agctcagcgc tgctcctcaa
    40681 gcgaatatcg cttggggagt aagcactcat cataaagtgt ttttttatac cttcaattac
    40741 ctgtcatgac agatatgttt gaaggcataa aaaaacattt taagcgagaa ataattgaaa
    40801 attttgtctt tttttgatag tgttagtagg aactttagga tgaagaagga gtaatcatgg
    40861 agccaattat tgaattagaa aagataaatt ataaatacca gccagatgat cttcgccccg
    40921 cattgaaaga tgtctccttt acaattgata aaggtgagtg gatcgctatt attggacaca
    40981 atggttcagg aaaatcgaca cttgccaaaa cgatcaatgg attgcttctg ccagaatcag
    41041 ggatcgtgaa agtgggaaat caaatattgg atgaagaaaa tatttggacg atccgacaga
    41101 tggttggaat ggtttttcaa aatccagaca atcagtttgt tggttcgaca gtagaagatg
    41161 acgttgcttt tggtcttgaa aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga
    41221 aagatgcact tgagaaagtt agaatggctg agtttgcttc acgcgagcct gctcgtttat
    41281 caggagggca aaaacaacgt gttgccattg ccggcgtggt tgccttacga cctgatatca
    41341 ttattttaga tgaagcaacc agtatgctag atccagaagg tcgtgaagaa gtgatctcta
    41401 cgatcaagaa gatcaaagaa gaaagtcaat tgaccgttat atctatcact catgatattg
    41461 atgaagcagc taatgccaat cggatactag tgatgagaca aggcgaactt gtccgtgaag
    41521 gtacaccaaa agaaattttt tctgctggtc ctgaactgat cgacttaggt ctagatctac
    41581 catttcctga aaaactgaag agcgcactga aagaacgtgg ggttgatgtg cccagtgaat
    41641 atatgacaga agaaaggatg gtggattggt tatggacatc cgttttgaac aagtagactt
    41701 cacttatcag ccgaatacac catttgaaca aagagcctta tttgacatca atatgacgat
    41761 caaagaaaac agttatactg cattagtagg gcataccgga agcgggaaat caaccttact
    41821 tcagcatttg aatgcgcttg ttaagccaac aagcggtaca gtccatattg gagaacgaga
    41881 tattcagccg gatacggata ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt
    41941 ctttcagttt ccagaagcac agctattcga agaaacggta gcaaaagaca ttgctttcgg
    42001 tcctaaaaac tttggtgtca gcgaagaaga agcactagtc ctagcaaaag aaacattaga
    42061 acaagttggg ctggatgaaa gctatttgga acgttcgcca tttgaacttt caggagggca
    42121 aatgcgtaga gtagcaatcg ctggtgtgct tgccatgagg ccggaagtac ttgtattgga
    42181 tgaaccaacg gcaggacttg atccccaggg cagaaaagaa atgatggaga tgttttggcg
    42241 tcttcataag gaacagcaga tcactattgt attagttacg catttaatgg atgatgtagc
    42301 caattttgca gattatgtct atgtgttgga aaagggacga atcgttaata gcggggagcc
    42361 gcaagaggtc tttcaaaaca ttgaatggct aaaagaaaaa caactaggcg tacctactgc
    42421 caccgagttt gcagaagaat taatggctaa agggatgaac tttgctacct tgcctttgac
    42481 agctgaagaa ttagcagacg ctatcgtcca ttatgctgga ggaaatgccc atgatgaata
    42541 aattgatatt tggtcgttat atgcctggag attccttgat ccatcgattg gatccccgag
    42601 ctaaattatt agccagtttt tattttatcg gaatcatttt tttagcaaat aattgggaaa
    42661 cgtacctttt gttggcattt ttcacattac tttctgtctt cttgtcaaaa gtagatttga
    42721 aattttttat ccgaggcatt cgcccattga tctggctaat cctcttcact gtagctttgc
    42781 aggtcttgtt tacaagtggc ggagaaactt attggagttg gggtgttttc catatcactg
    42841 aatttggtgt gatgaacggc ctctttattt tctgtcgatt cgtgttgatc atttttatgt
    42901 cgactctact cacgcttact acaccgcctt tggaattatc ggatgcgatt gagtacttgc
    42961 ttcgtccatt gaaagccgta cggttcccag tccacgaaat ttcattgatg ctgtcgattg
    43021 ctcttcgttt tgtgcctaca ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg
    43081 ctcgcggtgt tgattttggt gaaggaaacc tagttcagaa aatgaaagca gtcattcctt
    43141 tgctgattcc tttatttgtc agcagcttca accgtgcgga agatcttgcg actgctatgg
    43201 aagcaagagg ctacaaaggt ggggaaggaa gaacgaaata tcgtgtattg cattggcata
    43261 atagagacac gatggttatc attgcttttg tattattaac tgtgctactg atctttttaa
    43321 gaggataaac gttcagtggg ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa
    43381 ggatgcaagc agtgtatgac aagaaatatt agggtctgtg gcagactaag gtcacaggcc
    43441 tctttctttt atctgaaaag aaagaacgaa aaaattttat agaaaaatca ttattccaga
    43501 taacctttta ggaacaaagg agagaaaaac atggtacgtt acaaagcaat cattgcgtac
    43561 gacggaacaa attttaatgg attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa
    43621 gtagaaaaaa cattacaaaa aatggcaaat ggaaaagaaa tcacggtctt tggttcggga
    43681 aggacagatg ccggagtaca tgcgatcggg caagtaatcc attttgatta tccagaggag
    43741 cgtccgttag aacgaatgcg tttcgcgcta gatacccagt caccagagga tattgctgta
    43801 agacaagtag aaattgtttc agaagacttc cacgcaagat atttggtcaa agaaaagacg
    43861 tatcaatttc gagtggatat agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt
    43921 tattttcctt acccacttga tttggaaaaa attcagcggg cgcttcctga tttattaggg
    43981 actcacgatt tcacctcttt ttgtgcatca ggaagctcga tagaggataa aatacgtacg
    44041 atctacgagg ctaagatgga ggtaaatgaa acaaaagacg aattgttgtt tacatttagg
    44101 ggaaatggct tcttgtataa gatgatacgg atcttagtag gaacgctttt gaaaattggc
    44161 aatggccgat tgcctgaaga tagtatccca gatattattg cgaaaaaaga tcgtaatgca
    44221 gcaggaccta cagcacaccc tgaaggactt tatttgtatg aagtgaaata tgaataagag
    44281 gttatgatag aagtggtcag cttcaagaaa taagaaggta tttacgaaaa ttacttctca
    44341 aaattttgca aaatttcggc ttattttcga agaagctact tctggaacac cgtttaagaa
    44401 agaggtcgtg agcctgtcat ttaactctga gtcacaaaga gcaatttcaa aaaacagctt
    44461 ctcatctttg atgaatatcg tgacttgtgg acgaggcgtt gataagtgaa tcatcttttt
    44521 gttacctatt ttttctgtaa ccaaaaaacg atggaacgtt gttttgattg cccttggtgc
    44581 ggacagtctg aacaggttcc atcgtttctt tattttctac gtcttcttct gtgtgtgttt
    44641 cgtggttgtt cttctattgc tggatcaatc gtgccataaa aggggcgatt gcggtcaagg
    44701 taccagacat aaagaataaa caatgcaata cataggacaa aaaggattgc acctatcgta
    44761 aatccttcag gcaagtaact gaaagtgaca gtatgtttac ctgctggaac ttttatcatc
    44821 aagaatgcgt ctttgaaatt gctgaccttg actggtttcc catcaatttt agctttccat
    44881 cctttgtcat aaggaatagt tgtcaccaac atggaatctt cagcggtatt tacagtccca
    44941 gaagcttttc tgccagtggc ttccatttcg acaccttttt ctttgatctg attcattgcg
    45001 gcttgatagg ctacaacatc tagaccaacg actttaggct ccatgaaact tatttctttc
    45061 gtcccataaa aacttgcagt aaatgtcact gttgtctctt gaggataata gccaagatca
    45121 tagtattgac cagaaatgtt gatttgcgtt tttcgcgatg taccattgac agtgatcgtc
    45181 gcactagaac tttctaattg cgcaaaattg gttgggaaca aacttaagta agcttgtgta
    45241 tttgcaggca catggacttc ccaagtgagc tcttttggct ggttatctgc tgtttctgag
    45301 taagtgacgc cagtcgttgt ctttgtgatc gtcgtattca actgattctt caaagtaggt
    45361 gtatagaatg taaaatactg ttcatttaga ccagacaatg tattgatcaa gtttgtctga
    45421 ctggtcaaat tatctgtcac tggctgctca acatcattaa cggacaacgg tgcagtaaat
    45481 gctagtggca atgcattgac attctgatac agtgtatagt cgccgctttg accagcttgg
    45541 cggaagccat atttactgaa cgtgctttcg tttttagaaa tgttatattt gattcctgta
    45601 aacccatcca tcagcaaagt attattgtta taacggatat tcaaatttgt ccctcttgaa
    45661 cggaaaccta atttatccag gtaagaggaa gaattacgat ttcttataga agaaaacaaa
    45721 ctgataccac tgtaaccata gttgatcgaa tcgtttgcag atactggatc cagattttcc
    45781 aagcggtaaa acgagtcgga atcttttttt gtttcattta caagagcttt caagtcagga
    45841 taaggatcag tatataaact gcgggaagca taattccaat catcaagaat gccatggatc
    45901 atactgttcg tattgaccag tgcttcagca gacatgatca ataataacaa tatactcaga
    45961 tgattgaatg aaagtttttt atgctgataa aatcccacag caaaagcata aatccctaag
    46021 aaaaccactg tcaatacaaa ggaagtcatc gtcacatagg tgtagcttcc ttcaggtttg
    46081 atgccccatg ccaccgcaaa gagagcagct acgaccaaaa tgattcctaa caacagccca
    46141 cgatcgtctt gttctatctt ttcccatcct tttcctgcaa gcaggagcac taagaaagag
    46201 aacagatagg cataacggaa taaaaacata ttcggtgcat gcataccatg ccagaacaaa
    46261 ttcaatggaa caagataaaa acttgcgata agtatggcga aaagactgcc gtacaaaaat
    46321 ttatttttca acggtacttt ccgactggca aaataaaaca gacagaggac taatggtagc
    46381 agacctgcgt aaacgaacgg aatcgatccg tattttgtcg tgtcataaac accaatcata
    46441 tttttcatga ttagatccag ataagaagtc gcttctgttt tcaacgtagt gatctgactc
    46501 agtgcctcgc catttgaccg aagatccagc actgctggca atacaatgat cattgaagcg
    46561 ccgcctgcca gtaaagaagt gataccataa ggaacaatcg tttttttata ttctgaccag
    46621 tttgtcaata gacgggcgat aaaatataag aaagaaaata cgccaatcat aaaacccata
    46681 taaaaactgg ataaaaacaa gagtaaataa ctgataaata aaagtttcgg ccgtttaaga
    46741 tccataacac gatgaatccc caaaatcact aatggaagat aaacaaatgc atccagccac
    46801 atgatgatct ccgaatgtgc agtgataaat gagatcaatg cgtaactgac gctaagtgca
    46861 acatgccccc agcgaggaat cttgaacgta cgtgcaagaa accaaaaagc caatccggca
    46921 cagccgacct taagcaaagt cagaacatac agtgcatctg gcatcatctg gtttggaaaa
    46981 aagaacacca gtggcgtgaa gatcccgcct agatagtaag aaattaaaga taaataattc
    47041 aatcctagag aagcattcca tgtataaaaa atactttgct ttccaagaag aacatttcgg
    47101 aagctggcat gaaaattaga aaactgtgaa aaggcatcac ttgccaaaat acttctgctg
    47161 cttccaggat agattccgat acttagataa acaagtgcta aaatcaaaaa cggaatcagg
    47221 aaactagctg ctgcgtagcg tccgttttct ctaaagaatg actttaaatt ttttttcata
    47281 tttattttcc accaaatttc tatgaagttg tattcagttt atcatatcct tgtttttctc
    47341 tgcttaaaaa gagtctagtt ttcacaaaaa aataaaattt agaataaata acttcataat
    47401 ttgttcgtat aacaaaaata aacgcaaaaa aagggtagga atcaaaagtc ccacccttaa
    47461 aaatttttat taaataaaaa accgttcact atctgaacgg tccaagtatc attcaattaa
    47521 acgcgttcaa cttttcctga tttcaaagca cgagttgaca cccaaacttt tttaggtttt
    47581 ccgtcgacca taacgcgaac tttttgtaag ttaggtttaa cagtacgttt tgttgagttc
    47641 atagcgtgtg aacggttgtt tccacttttt gtcttgcgac ctgtaaagta acaaactttt
    47701 gccatggtaa tttcctcctt tgccttgatt tggagcaata gaataattca gctcatacca
    47761 gactaacata tcatatagaa tgggaatttg caagtacatt ttcatagata caattgacaa
    47821 ttgagaagaa taattgtaaa ttaaacaagg ttatacctga aattttgcaa ggtttttgag
    47881 tactttgggt aactgccttt tatttcaagt tgcgctatga taaaatatga tagaagaaaa
    47941 atgggagttt tttacccgtt aaggaggctc attcatggct gtaaaaattc aaacgtcagc
    48001 tggaaccatt gaaattacca atgatgtaat tgcaacagtt gttggtggcg ccgcgacaga
    48061 tgtgttcggt gttgtaggaa tggccagcaa aaatcaaatt aaagataata ttactgagat
    48121 tttgcgtaaa gaaaattact caagaggagt agttgtccgc caagaagata atggtattgc
    48181 tgtagatgtt tatacgatta tcagctatgg tacgaaaatc tctgaagttt cccgcaacgt
    48241 ccaagaaaaa gtgaaataca atctagaggc attattaggc gtaactgcca attcagttaa
    48301 tgtctttgta caaggtgttc gtgtactgcc agactaggca ggagactggc tggtaactca
    48361 gcagtcgatc tgaaggagga ttatctaggt gagtgtaaca gaaataagtg caagccagtt
    48421 ccaggaaatg gtccaggcag gtgcgaatcg tctgcaagta aatgcagaat acgtcaattc
    48481 attaaatgta ttccctgtgc cagatggcga tacgggaaca aatatgaatc tatctatgac
    48541 tagtggagct aaggcagtag tagattcaac ctcagaaaaa gtaggagaat tagcagcaat
    48601 gctttcaaaa ggattgctga tgggtgcgcg cggaaattcc ggcgttattt tgtctcaatt
    48661 gtttcgtgga ttttctaagc aaattccaga tgttgtctca ttaaatgctt ctgatcttgc
    48721 tgcagccttc actcatggag ttgaaactgc gtataaagca gtaatgaaac cagtagaagg
    48781 aacgattttg acagtagcta gagaagcagc gaaagctgga gaaaagaaag caaaaagtac
    48841 tgatgatgtc gttgaagtaa tgacagctgt tgtaaaagga gcaaagcgtg ctttagctaa
    48901 aactccagac ttgcttccag tcctaaaaga agtcggtgtc gtagacagtg gagggcaagg
    48961 actgctgttt gtttatgagg gctttttaag tgcattgaat ggagaattcc aagcggatga
    49021 aacatatgaa ccttctccag cagaaatgga tgatatggtc aatgcagaac atcatcgcag
    49081 tgtccaaggt caaatggcga cagaagatat ccattttggt tactgtacag aaatcatggt
    49141 aaaaatcgga gaaggaccta cagtcgatag tacattcgat tacgaagaat tccgtaacta
    49201 tttagatggt ataggagatt ctttacttgt ggtcaatgat gacgagatca tcaaagtcca
    49261 cgtgcataca gaaaacccag gagaagtctt gaattatgga caaaaattcg gttcattagt
    49321 caaaatcaaa gtcgacaaca tgcgcttgca gcatgagacg attttggaac acgatgaaga
    49381 agtgaacgag tttgcgaaaa aagaaatacc acgtatcccg tatggtatcg tagcgatcgc
    49441 tgctggtaaa ggcgtccaag agctgtttga aagtttaggc gctaattatg ttatcagtgg
    49501 tggacaaaca atgaatccaa gtacggaaga cattgttaaa gcgattcaag aagtaaacgc
    49561 agataaagtg attgtcttgc caaacaataa gaacatcttc atggcagctg atcaagcagc
    49621 agaagtagca gatatcccag tagcagttgt tccttcaaga acgatttccc aaggattgac
    49681 agctatgctt tcattcaatg atcaagcttc tttagaagaa aacaaagaaa cgatgacaga
    49741 aatgttgtct agcgttgtga gcggtcaagt cactcacgcg atcagagata cctcaattga
    49801 cggtgtagag atcaaagaag gagacttttt gggcatgatc gatggaaaaa tcctgatctc
    49861 taacccagat atcacagcaa cagcgttaag tacactagaa caaatgatca atgaggacac
    49921 agagatcgta acgatcttgg caggtgatga aggaacagtt gaacaagcaa atgaatttgc
    49981 tgagaaacta acagaaaaac atcctgattt ggaaatcgag atccaccaag gagatcagcc
    50041 tgtctatcct tatctatttt ctgctgaata atttctgtgt cagaatatct ttctaacaca
    50101 gtattcattc ataaaaggcc ttcggttagt gatcaggtat gatcgctgac caagtccttt
    50161 ttttgttaaa ggagggagga aaaatttatg cgttctttag atgatccaat cactatgctg
    50221 gcaggagtcg gagaaaaaag agcagctagt cttgccagct tgggcatcca aacgattgaa
    50281 gacttactga cttattatcc ttttcgctac gaagatattc aggaaagaaa tctaaacgag
    50341 atccaggatc aagaaaaggt tactttgaaa ggaatcgtag tctcgcctcc tgtgatgaat
    50401 cgatttggtt ataaaaaaag ccgattgcaa tttcgtatga tgcaagaaca tgatgtgttc
    50461 aacgtttctt tttttaatca accttatcta aaagaaaaag tcattttatc ggaggaaatc
    50521 gccgtatacg gtaaatggga tgcaaagcgt aaagccttga acgggatgaa gattttaggt
    50581 tctcaaacaa tggatgactt ttcgccgata tatcacgtca acaaatcaat tcgtcaaacg
    50641 acattagttg atctaatcaa aaaagggttt caagaatacg gcacattgat tgaagaaaat
    50701 ctgccaaaca accttgtgga gaaatatcga ctgcttgacc gagcttctgc tgtaagaagt
    50761 atgcattttc caaaagacca cgaagaaaac catcaagcca aacgacgtgt cgtttttgaa
    50821 gagttctttt tatttcaaat gcgtcttcaa ggattgaaaa aagcagaaaa agcagaaacg
    50881 aatggtttgg agatccttta tgatgtccaa aaattgaaac aatttactca aaagctacct
    50941 tttgaactga caaatgcaca aaaacgtgta acgaatgaaa tctgtcggga tcttcgcagt
    51001 ccgcagcata tgcagcgact tttgcaggga gatgtaggta gcggaaaaac agtggttgcc
    51061 gcgattgcgt tatacgctac cgttacagca ggtttccaag gtgcgttgat ggtgcctaca
    51121 gaaatcttgg cacaacaaca tatggaaagc ttgcaacagc tgtttgatcc caatgaagta
    51181 accatcgcat tgattacggg gtcaacgaaa gcaaaagaac gacgtgagct ccttgaaaaa
    51241 ctagagcaag gggaaattaa cgtcgtgatc ggcacacatg cattgatcca agatggagtc
    51301 gaatttcaga atttaggtct agttattacg gatgagcagc accgttttgg cgtgaaccag
    51361 cggaaagtac ttcgtgaaaa aggctggcga ccagatgtct tatttatgac agcgactccg
    51421 attcctagaa cattagctat tacagcatat ggtgagatgg atgtatctat cattgatgaa
    51481 cttccagctg gacgtatccc gatcgaaaca cgctgggtaa gaacacctca attggacagt
    51541 gtactggatt ggacgaaaaa agaactggca agaggacatc aaatgtatgt catctgtccg
    51601 ctgattgaag aatcagaagc attagatgta aaaaatgcag tggaaatcta tgaaaaactt
    51661 cgtgaactat ttgcaccaaa atatgaagtt ggcttgttac atggtaaaat gaagaatcag
    51721 gaaaaagaag taatcatgga agccttcaaa gacaaccaga tgcagatatt agtttcgact
    51781 actgtaattg aagtaggggt aaacgtgccg aacgcgaccg tcatgctgat catggatgcg
    51841 gatcgatttg gattggcaca gctgcaccaa cttcgtggac gtgttggacg cggaagtgat
    51901 gcttcctact gtatcttagt tgctaatcct aaaaatgaac taggtgtgga acggatgaaa
    51961 atcatgacag agaccaccaa tggttttgta ctaagcgaaa aagatctgga attacgtggt
    52021 cctggtgaag tatttggctt ccgtcaatct ggtctgcctc aatttgcgat tgctgacttg
    52081 gtgacggatg gaaatgtttt ggaggtagcc agagaagagg ctgcagccct ttggcaaata
    52141 aaggattggc agatgcttcc tgagtatcag cctttagcgc aaagcctcca aatagaaaat
    52201 caggataatc gttatttcga ttagcagact gtgctatact ttatactgat gacggaaaaa
    52261 ggagtggaaa caatgaaaat tgccgtagat gcaatgggcg gagatcacgc acctcaagca
    52321 attgtagaag gcgtggcttt agcgcagcaa gattttccag aagtagaatt cttactttac
    52381 ggaaaagaag cagaaatcaa gaaatactta acaaatgaaa aaaacatcac gattatccat
    52441 acagacgaaa aaatcaatag tgatgatgag ccagtaaaag caattcgacg aaaaaagact
    52501 gcatcaatgg tccttgctgc acaagcagtg aaaaacggtg aagcagatgc tgtattttca
    52561 gcagggaata caggcgcgct actagcagca gggttgttca tcgtaggacg tatcaaaaat
    52621 atcgaacgcc ctggcttgat gtctaccttg ccagtagtag ggaaagaagg tgccggtttc
    52681 gatatgctgg atcttggcgc taacgcagaa aacaaaccag aacatttgtt gcaatacggt
    52741 attttaggtt ctttttatgc acgtaaagtc cgaggtatcg gacgtcctcg tgtcgcactc
    52801 ttaaacaacg gaacagaagc aacaaaaggt agtgaagtga cgaaaaaagc ctatgaactc
    52861 cttcagaatg aaacaagctt gaattttatt ggaaacgtag aagctcgtga gctactcaat
    52921 ggtgtggctg atgtagtggt cacagatgga tttacaggca acgctgtttt gaaatctatt
    52981 gaaggaacag caatgaatat gatgaatcta ttaaaatctg ctattctaaa tgaagggatc
    53041 aaaggaaaaa tgggcgctat gcttttaaaa gacggcttac gttctttgaa agcagaaatg
    53101 gattattcca aacatggcgg tgccgttttg tttggcttga aagcaccagt cattaaaact
    53161 catggagcaa caggccccga tgctgttcgc tatacgatcc gccaaatcca cacaatgctt
    53221 gagacagatg tagttggaca attagtcgaa caatttgaaa aaagcgaaga atagtatttg
    53281 gatatctgaa gcgatccgtt ccattgaaaa aaaggtggac attcctgaaa aatgccagta
    53341 aaattagcca tggtgtaggt aattgacaag tgtatgattc ttggaggtga aaaagttgac
    53401 tcgcgaagaa gtatttaaca aagtagcgaa aattatttca aatcattttg agatagatac
    53461 cgataaagtg acggatgaat tgaacatcaa agatgattta aaagctgatt caattagtat
    53521 tatggaattc gttttagagc ttgaagatga attcggtacg gaaatttcag atgaagacgc
    53581 tgaacaaatt gaaacagtcg gtggcgcagt agattatatc agcagccatc ttaaataatt
    53641 tcaaataaaa gcaaagaagg ataaaaagct gcatgcagct ttttatcctt ctttttttaa
    53701 tctttttgac acgtaaaagt catttttctg ataattctgg cgataaacag aaattatgtt
    53761 gcaaagtaaa gcggttttct atataattat taataattca ttacacaaag ataagaataa
    53821 cctttgttat aaaacgattt attctgtgta atgtcctttt ttattaagaa aaacttccat
    53881 ttaggaagca gagaggggta ttcgattgtc cgataaccaa ttattagaag ttcagaacct
    53941 acatacagga ttccgactca aagatgacta ttacgatgca gtagatgacg tttcatttac
    54001 tttagacaaa aacgagattt tagcaatcgt tggggaatct gggtgcggga aaagtacctt
    54061 ggctactacg attatgggat tacttgatcc taataacaca aaaattacag gtgagatttt
    54121 atataacgat ctgaatttaa tcgacctgaa cgaaacgctc tataataaaa tccgcggaaa
    54181 tgatatcgga atgattttcc aagatccgtt gtctgcatta aatcctctca tgagaatcga
    54241 agaccagatc aaagaaggac tttcctatca cacaaagatg aatgcagaac agcgtcaagc
    54301 tcgtgcacta gaattgctag aacaagtagg gattcctaat cctgcgagag ttggacgcca
    54361 atatccccat gaactatcag gcggtatgag acaacgtgtc atcatcgcaa tcgcaatcgc
    54421 ctgcaaacct ccaatcgtca ttgcagatga accgacgaca gccctagatg taaccatcca
    54481 agcacagatt cttgatttac tgaaagacct tcaggaagaa acaaaaacag ggatcatctt
    54541 gatcactcat gacttaggag tcgtagcaga aatggctgat cgagtggcag tgatgtatgg
    54601 cggacagttc gttgaagtag caggtgtaaa agaactgttt gatcatccta agcatcctta
    54661 tacacgctct ttactgaact ctataccaca agaaggaaat catgatgcag aactccatgt
    54721 gatcgaaggt gtcgttcctt ctctgaaaaa catgcctcgt aaaggttgtc ggtttgcacc
    54781 acgtattcca tggataccag caagcgatca tgaagaagag cctatccttc atgaagtcgc
    54841 accgaaccac ttggtacgtt gctcctgcta taagcatttc cactttagag acgaaaaagg
    54901 agaggtgtag atgacagaat taatcacaat caaagacctg aaagttcatt accctattcg
    54961 cagtggattc ttcaatcgag taacggatca tgtatatgct gtagatggtg tggattttat
    55021 tatcgaaaaa ggaaagacat atggtttagt gggagagtct ggctctggaa aatctactac
    55081 gggaaaagcc gttgtgggat tagaaaaggt aacagccgga caaatcatgt atgaaggaaa
    55141 agatgtaacg aagcgaagca accgcaaaaa aatgggttat aacaaggatg tgcagatgat
    55201 cttccaagat tcaatgtcca gtttgaatcc taaaaagcga gtgttggata tcattgctga
    55261 acccatccga aattttgaac ggttaagcga tcaagaagaa aagaaaaagg taaaaggact
    55321 gctagatatc gttgggatgc cggaagatgc gctatataaa tatcctcatg aattttcagg
    55381 cggacaacgt caacgtctag gagtagcccg tgctgttgct accaatccaa aactgatcgt
    55441 agccgatgaa cctgtatctg ctctggatct atctgttcaa gcgcaagtat tgaatttcat
    55501 gaaacgaatc cagcaagaat acggcctcag ctatttattc atttcacatg atttaggtgt
    55561 agtaaaacac atgtgcgaca atatcgcaat tatgtacaaa ggtcgatttg tagaaatcgg
    55621 tacaagagaa gacatttata atgacccgcg acatatctat acgaaacgtc tgctttcagc
    55681 tattccgcaa atcgatgtag aaaataggga aagccacaaa gaaaatcgac gaagagtaga
    55741 acaagagtat atccaaaacc aaaaagaata ctatgatgcg actggtcgag tctacgattt
    55801 gcgtacgatc acaactacac acaaagtggc gttgaaagat ggaggtgcaa gctaatgtgg
    55861 aaaacgattc tgcgacgtgt tttattgatg atcccgcaag ttattatttt aagtgttctg
    55921 atcttcttat tagcccaagc gatgccgggg gatccattta ccggtttgat caatccaaat
    55981 caggatccgg cagtgatcga acagatgcga caagcagctg gcttgaatga cccatggtat
    56041 gtccagtact tccgttggat cggaaatgct ttgcaaggcg attttggtca aagtttctta
    56101 tacaaacgct ctgttgctga cttgatcggc gaacggatca tcaacacttt atatctatcg
    56161 atcttgacag ttgtccttac ttatttgatt gctgtgcctc tggggatgct tgctggccgg
    56221 tatcaaaatt caatcttgga taagattgtc gtaatctaca acttctttag ttttgctgtt
    56281 cctttattta tcttcggctt gatcatgcta tttgtttttg gttatcgttt aggctggttc
    56341 ccaacaagtg gatcacaaac actaggtttg caaggtggat ttatcactca atggatagac
    56401 cgtttgaaat atattctgtt accatcaatt acccaagcat ttttggcgac tgccgtcaca
    56461 atccaatatc tgcgaagtga agtaatcgat tcgaaatcgc tcgattttgt cagaacagcc
    56521 cgttccaaag gggtaccgac gaataaagta ttcagtcgac atattttccg aaatgcagcg
    56581 ttgccgatgg cttctcaaat ggggtatgaa atcacttcgt tgattgctgg ttctgtagtt
    56641 atcgaaaaga tttttggtta tccgggagtc ggaaaactat ttattgattc catcggccaa
    56701 cgggactata ccgtgatcac atccttagta ttgattttag gaatcgcgac gctagtgggg
    56761 acattacttt cagatatcat catgagtatc gttgacccgc gtattcggat tcaataaaac
    56821 caatcagaaa ggagaatgga tcgatgagtg aaaaaaacaa tacagcagtt caagaaagta
    56881 ttcctcctat ggggatacga atgattgctc gagaatttaa aaaagataaa attgctattt
    56941 tttcattagg tttgctagtg gttttattat tagtgatctt tatcggtgcg atgctgaccg
    57001 atcaagacaa agtgatgtat gttagtatct tcgacaaata cgctgcacca ggaacagttt
    57061 cgacacaagg acaaaagttc attctgggag cagatgaagg cggacgtgat gtattaggac
    57121 aattgatcat aggtgctaga aactctgtta cgatcggatt tgcgatcacg atccttactt
    57181 cgatcatcgg ggttggatta gggatcatct ctggctacta cggagggatc attgacaaca
    57241 tcttgatgcg gatcgttgat tttatcatga ttctaccgat catgctgatc attatcgtct
    57301 tcgtatcgat tatttccaga tacaatgtct ggtcctttat attcatcatg agtgcatttt
    57361 attgggtagc taaagcccga ttattccgaa gcaagacatt atctgaagca agaagagatt
    57421 atgtcagtgc ctcaaaaaca atgggaacca atgattttaa aatcatgttc cgcgaaatca
    57481 tgccgaatct aagttcatta atcattacta atttgacgat gaactttgcg gcaaacatcg
    57541 gtatcgagac aactttgact ttcttaggtt tcggcttgcc ggcaaatgta cctagtttag
    57601 gtacattgat cggttatgca agtaacggag aagtcttagt gaatcggcaa tggatctggt
    57661 tacccgcatc aatccttatt ttagttttga tgttgagtat caattatgtt ggacaagcat
    57721 tcaagcgttc tgcagatgcg cgccaacggt taggctagta tagaagcgaa ggggggaaat
    57781 aggaatgaag aaaacgattt ttggatttgc agcgctgatg tctgctgtcg ttcttgcagc
    57841 atgcgggggc ggaggtacag atacctctgg aaacaactct ggaggcaacg gcaataacaa
    57901 agaggaatta acttttccaa ttgcaacaaa aaataatgat gatgcaatcg aagacggcga
    57961 attagaagct gcggtcgcaa cggacagtca gtttaaagga ttgttccagt gggagtttta
    58021 ccaagattca tatgatgcag cttttatggc tccttctcat gaaccgctat ttgcaaacga
    58081 tgacgatttc agaatcacag acgacggagc tgcaacgctt gatctagatg aagatacgaa
    58141 aaaagcgaca atcaaagtaa aagacaacgt caaatggtca gatggtgaag atgtaacggc
    58201 ggacgatgtg attttccctt acgaaatcat tgggaataaa gattacactg gtatccgtta
    58261 tgacgacact ttccgtaaca tcgtaggtat ggaagaatat catgatggaa gtgccgacac
    58321 aatctccgga atcaaaaaaa tagacgacaa aacagttgaa atcgaatata aagaagtaaa
    58381 cccaagcatg cttcaatcgg gtggtggtat ctggtcatat gcagcaccaa aacatacgtt
    58441 agaaggtgta gcaatcaaag atatggaatc aagcgatcaa gtacgtaaaa atccagtgac
    58501 ttttggccct tattacatga gtaatatcgt tgcaggagaa tcagtagaat acttgccaaa
    58561 cgagcactac tggaatggta cgcctaaatt gaaaaagatc acgatgaaat ctgtaccgat
    58621 ggcaagtgca actgaagcat tgaactctaa attatatgat atgattttcc aaatgccaac
    58681 agatacttac gatacctata aagaaattgc tggctataca aacttaggcc gtgaacaaac
    58741 ttcttatact tatctaggat tcaagttagg taaatggaat gcagatacaa agagtgtgga
    58801 atacaatcca gattcaaaaa tggctgataa atcattacgt caagcaatgg gctatgcatt
    58861 agataataat gcagtaggtg aacgtttcta tgcaggtttg agaagcaatg cgacttcatt
    58921 gattcctcca gtattccagt cataccatga tgatgagatg aaaggattca cacaagatct
    58981 agacaaagcg aaaaaactat tagatgatgc tggctacaaa gatgtggatg acgatggttt
    59041 aagagaagac aaagatggaa ataaactaac aatcaacttt gcttcgatgt ccggtgggga
    59101 aacagcgcaa ccattggcag attactatat ccaacaatgg aaagaaattg gtttggatgt
    59161 ccaatacaca acaggtcgtc tgatcgaatt caattctttc tatgataaat tagaaaacga
    59221 tgatcctgaa attgatgttt accaagctgc ttggaataca ggaactgatc caaatccaag
    59281 tggactatgg ggaccaaatg ctgcgttcaa ctacactcgt tatgaatcag aagaaaatac
    59341 aaaattgatc aacgatatca gttcaagcaa agcatttgat gaagagtacc aaaaagaagc
    59401 atatcaaaaa tggcaacaat atgcatttga agaagcattt gcgattccaa cgttgttccg
    59461 taatgaagta ttgccagtca acgaccgtgt caaagactgg gattggtctt atgatgtacc
    59521 aaacccatgg gcaaatgttt ctgttacagc agattcacgt tcataatcac taaaaatgac
    59581 cgaaaaaggg cgatgtcctt tttcggtttt ttgatatttt tctgtttatt tctctaatat
    59641 tcaggtcaag gcgctgattt catgacttct ccaataaacg gtgttcaaag tccagtttct
    59701 cggtattaag tcaaatttat gcaaaaatat ggaaagccat tttcacaaaa ttttttcttc
    59761 atactcgaaa ctaaacgaat ttttcacaac ttctcgtcaa tcactaggat tattaaagct
    59821 ttacttacct tttgaccgaa ccatttcaaa tttgacaaaa aaccagtata ataaggaagt
    59881 atcgaaaaaa tatccataaa aggaatgtgg aaaatggaca accagctgac aaaagaacta
    59941 aaagaaaact ataacatcgt ttttcacgat ctaaatttgc ttgaacaagc ttttacccat
    60001 tcatcctatg tgaatgagca tcgcaatctg caattatcgg ataatgagcg acttgaattt
    60061 ttaggagatg ccgttttaga actgatggtt tctcagtatt tattccgttt atatcctcat
    60121 ttgccagaag gaaaattgac aaaaacacga gctgcgatcg ttcgcgaaga cagcttgtcg
    60181 aaatttgcca aagaatgtca ctttgatcaa tatgttttgt tgggcaaggg agaagagaat
    60241 tcaggaggac gtacgcgacc agcattgctt tgcgacctat tcgaagcttt tttaggcgcg
    60301 ttatatcttg accagggatt cgacacgacc catgcattca tcgaaaaagt gatttttcct
    60361 aaagtcaaag caggtgcttt ttcacatgag atggatcata aaacaaaact acaagaagtc
    60421 ttgcaaaaat caggtgatgt atcaatcgaa taccgattga tcaatgaaga aggtccagct
    60481 catgaacgag tattttggat cgaagtttat gtagatgatc aattgattgg cactggacaa
    60541 gggaaatcga aaaaattagc agaacaagct gcggcggaaa atgcattggc agcactgtaa
    60601 aagtaagtga gggaaagctt tgtatttgaa acgaattgaa atagccggtt ttaaatcatt
    60661 tgcagacaag acagtcattg attttgaaaa tagcgtcaca gcagtggttg gaccaaatgg
    60721 cagcggaaaa agcaatatta cagaggctat ccgctgggta ttaggagaac aatctgctaa
    60781 aagtctgcga ggcggaaaaa tgccggatat catctttgcc ggttccgata cccgtaagca
    60841 gctgaatatt gcagaagtca cagtgatttt agacaatagt gatcattatc tgccattgga
    60901 gtacaatgag atcagtgtaa cccgccgtta tcgacggact ggggaaagcg agtttttcat
    60961 caataaacaa agctgcagat taaaagatat ccaagaattg ttcttagatt ctggattagg
    61021 aaaagaatcg ttctcaatca tttctcaagg aaaagtagaa gcgattttca gtagtaaacc
    61081 ggaagaccgt cgtgggatct ttgaagaagc agctggtgtc ttgaaataca agcagcggaa
    61141 aaagaaagca gaacagaagc tttttgaaac agaagacaac ctcagccgcg tccaagacat
    61201 catccacgaa ttggaagaac agttaactcc tttggccgcc cagagtgagg cagcaaagga
    61261 gtttttacgg ctaaaagaaa cactgactca aaccgatgtc tctttgatgg ttgctgaaat
    61321 caagacagca aaaaaagatt gggacaacaa acaagcacag cttgcgaaat tcaatctaga
    61381 attaggcaaa ctatctgagt cgatccaaga acaagaatcc attttggcga agcagcgtaa
    61441 agaaaatgcg caagccgatc gtctgatcga aaaaaatcag caagtattat tagatctttc
    61501 ggaaaaactg aagcagacag aaggacaaaa agatgttttg caggagcgga caaagcatac
    61561 acaaaaaagc tcgcaagaat atcaaacttc attagcagaa gcacaaaaaa aggttaaaca
    61621 ttttgaaaag cttcaagaaa gcttgatgaa agcagcagca gaaaaagaaa cagagatcca
    61681 aaaagctgaa gcaaatctca taaaaacaca gcaagaatta gaaaaatacc aaaaatcaac
    61741 gaaagaatta ttggcagaat taagagatca atatgttgat ttgatgcaag aacaagcagc
    61801 tgtaggaaac gaactgaagt atctagaacg tcaatatata caagaaacag caaaaagcaa
    61861 gcagacgtta gccaagcaat cggaagtaga agcatcagta gaccgattga tcttacaaaa
    61921 agaagaattg acacaaaagc aggcgcagct aaaatcatct ttaactgaaa caaaagagaa
    61981 gttagaaatg atccaacaaa acgggaaaaa gttccaagaa gcattagcaa aagaacagcc
    62041 taaaatgtat caattaatga atcaagtcca gcagctacgt gctcgtaaga aaagccttca
    62101 agaaatccaa gaaaactatt ttggttttta ccaaggggtt cgattggtct tgcagcataa
    62161 acagcagctt tcgggtattg tcggagcagt ggctgaactg atcgatgttc ctgcagattt
    62221 cacgttagct atcgaaacag ctttaggtgg ggcagcccag catgtcatcg ttgaaaatga
    62281 aaaagatgct cggcaagcca tcacgtattt gaaacagcaa agaggaggaa gagcaacatt
    62341 ccttccactg acgacaatca aaccaagaca attaccggct catatattga cacaagcagc
    62401 agctgtagaa gggtttatag ggattgccag tgaacaagtc agttatcccg atcaaatcca
    62461 aactgtggtt caaaacctgc taggaacgat ccttttagcc aaagacttaa ctagtgccaa
    62521 tgcaatcgcg caaacgatcc gctatcaata tcgagtggtt tccttagaag gtgatgtgat
    62581 gaatgccgga ggatccatga caggtggagc gaataaacga ggaaaccaag gcagtttgtt
    62641 tgtacaaaat caagaattga aacagttgac tagtgaattt gaagaagcag ataaacaact
    62701 ccaagcacaa gaaaaaaaag ttcaggagct gcaacaagaa acagctcgtt tagccgaaga
    62761 acaagaagtt ttgcgtacac gaggcgaaca attacgtttt gaagaacaag aagcgacaaa
    62821 tcagctacaa aacatcataa atgaacttga acgttttgaa aaagaaaagc aaatctcaac
    62881 ttttgagaca cgtgaactgc agcagtttat cgaagattac gaaaagcaaa cgaacgaatt
    62941 gaaagacaaa caaacagatc ttgaatcgca acgacaaaaa atcgacgaag aaatcaaatc
    63001 gttaagtcaa gaaagcgacc agatggaagc cagaagagca caagtacaaa gtcaaaaagc
    63061 acaagaacaa gcagatcttg ctgtcttgaa agagcagttt aatcatctgc agatccagct
    63121 ccgcggtgcc cgagtccaaa aagcagaggc aaccgaacgt caagaagcga tagaaaagca
    63181 gttggcgaca ttgacagcag acttttctga tcatgaagtc acagaagaaa gtttggaaaa
    63241 acaaattaac gaattatctg ctcagcgaga aacattaaaa gccgagttgg caaaagccaa
    63301 agagcagcga gatagaaggc aaaaggagat cgataagctt gaagcagtct tggcagagcg
    63361 taatcgtgag caaaaagcac gactgtcgga acaatccaaa ttagaagtcc aaaaagaccg
    63421 agctgaaatg attttagata atcatttgac ctatctgcag tcagaatatc agctgacatt
    63481 tgagaaagct tcccaagact atcaagaaac aaccgatatc gaagacagta gaacaaaggt
    63541 ttcatcctta aaagaacaga ttgaaaaact gggaccagta aacttaaatt caatcgaaca
    63601 atacgaacaa gtcagtgaaa gacatacatt cttagcaaca cagcgagatg atctgttagc
    63661 agcgaaaaac caattgtttg aaacgatgga tgagatggat gatgaagtgc ggacaagatt
    63721 caaagaagta tttgaagcta tccgtcaaga attcaaaatt gtctttccaa atatgtttgg
    63781 cggcggtaaa gctgaattag tactgacgga accaactgat ttgctgaaaa caggtattga
    63841 gattgaagta caacctcctg gcaaaaaact gcaaagtcta agtttgcttt ctggaggaga
    63901 acgagcactt acagccatcg cgttgctctt ttccattatc cgtgtctgtc ctgttccgtt
    63961 ttgtatctta gatgaggtag aagcagcgtt agatgaagcc aacgtgaaac gttttggtcg
    64021 ttacttgagc gatttccaag atgacacaca atttatcgta gtcacacacc gcaaaggaac
    64081 gatggtcgca gcagatgtac tgtacggagt gacgatgcag gaatccggtg tatcaaaaat
    64141 cgtttctgta cggatggaag atatcaatga agaggcgaaa atcaacgaaa cgaaagtgta
    64201 ggaacgaaaa tgatcaaatt agtagcaatc gatttggacg gtacattatt aaatgaacaa
    64261 aagctgattt cagatgagaa taaacaagca ttagcacaag caaaacagca aggggtcaag
    64321 atcgttctat gtacaggacg ccccttagct gcgatggcgc attatctgca agaattagga
    64381 ctggtagatg aaggtgacta cagcatcact ttcaacggcg gtttggtaca aaaaaatgat
    64441 actggtgaaa tcatggaaaa gaaagtgatg gaagtatcag atatccaacg cttatacaaa
    64501 ctggctcagc aattggatct gccactagat gttttgtctg acaatgtggt tttacagctg
    64561 cctagtgccc caaggaagca atccttgtac aatgtgttga ataagctgct gcaattccaa
    64621 ccagcggata taagcgatat tacagatgaa tttgtgctta ataaggcagt aatcgcttat
    64681 gaccaagaag aattagatcc taaaatcaaa gaaataccag cagaattcca tgaaatgtat
    64741 gagatcatca aaacaagaag tatgcttttg gaatttatgc caaaaggtgt tacaaaagct
    64801 tatggtattt ctttattggc aaaagatctt ggtttgaaac aagaagaaat catggcgatc
    64861 ggtgatgagg aaaatgattt accgatgatc caatatgctg gactaggcgt agcgatggag
    64921 aatgctgtgc ctttcgtcaa agaagcagca gatttcgtga cagccagcaa tgaagaaaat
    64981 ggcgtagcca aagtgatcca aaaatttgta ttagagtagg gggagtcaaa tgggattttt
    65041 tgataaaatc aagcgtgctt ttactggcga agagaaaaca gaagaagttg aagtacagga
    65101 gaagtacgac aagggtttag aaaagacgcg taaaacattt ggtgaacgga tgaatgagtt
    65161 gtttgccaat tttcgaacag tcgatgaaga cttttttgaa gaattagaag aaacacttat
    65221 cggtgcagat gtaggttttg aaacagcgat acgaattacc gaagcattac gtcaagaagt
    65281 gaaactcaga aatgcgaaaa aatcggcaga agtccaaaat gcgatcatcg agaaacttgt
    65341 ggatctctat gaagcggaag gaatcaatga agtaaatgaa ctaaatatcc aagaagacgg
    65401 actaacagtt attttgtttg tcggtgttaa tggtgtaggg aaaacaacaa gtattggtaa
    65461 acttgcccat cagttcaaaa acgaaggtaa aaaagtattg atggcagcag cagatacctt
    65521 ccgcgctgga gcaatcgacc agttagttgt ctggggcgaa cgcgctggtg ttgaagttgt
    65581 tcgtggcaat gcaggaggcg atccagcagc tgtcgtattc gatgctttgg aaagagcaaa
    65641 gacagagcag gcagatgttt tactagttga tactgcaggc cgactgcaaa ataaagtgaa
    65701 cttgatgaac gaattagaaa aaataaaacg agtaatccag cgggaattac cagaagcacc
    65761 ccaagaaaca cttcttgtat tagatgcaac cactggtcaa aacgcgatgg ttcaagcaaa
    65821 acaattcaaa gaaacaacag atgtgaccgg tcttgttttg acaaaattag atggtacagc
    65881 aaagggcggt atcgtacttg ctatccgtaa tgaattgcat ttaccagtga aattggtcgg
    65941 tcttggtgaa ggaatcgatg acttggagcc gtttgatcca aatgattttg tcgttggatt
    66001 gttcaaagga ttactaaaag aagaataacc catgtctaaa aagcaggagc tgtgacaaaa
    66061 gttgcagctc cttgtttgaa tgattgtttt taacatagct gtgtttttga tgccttcatt
    66121 tttatactta tttgtaagcg gttctcaaac aatttcgttc tttttcttag actttttgat
    66181 tataattaga ttcatatgaa ttggaggtca cttaatgatg aattttaagc aattattatt
    66241 gcatgtcaat gcgcgccctt ttatcgacca agctcgattt ggtatagaac gggaaggaca
    66301 gcgggttgat cttgcaggaa atctagcaaa aaccgatcat ccagcaatct ttggcgatcg
    66361 atcctatcac ccctatatcc aaacagattt tagcgaaaca caaacagaga tgatcacccc
    66421 tgttaccgat tctattcccg aattatttca gtatctcgct gctgtttatg atgtgactgc
    66481 tcgttctata ccgaaagaag agatgatctg gccattaagt atgccacctg ccttaccgga
    66541 aaaagacgaa gagatcatta ttgcaaaatt aaaaaatttc gaagatgtct tgtatcgacg
    66601 ttatttagca aaagaatacg ggaagcgaaa acagatggta agcggtattc atttcaattt
    66661 tgaatttggc gatgagttgc taagaacatt gttcagccat caggaagaat ttcaagattt
    66721 ttccgaattc aaaacagaac tttatttgaa aacagcgaga aactttatgc gctatcgctg
    66781 gatgatcact tatttattcg gtgcttcacc aatgagtgag aagaactact ttttagatga
    66841 atcacatccg caagaacctg ttcgcagtat tcgcaacagt gcgctgggct atacgaatca
    66901 tccaaatgtg aaagtttcct atgcttctat gaaacagtat ttagcagata tcgagcgaat
    66961 gatcgaagaa gggaaacttt cggaggagaa agaattttat acaccgcttc gtttccgagg
    67021 cggaaagaaa gtcgcagatt tagcaacaac aggtgttcgt tatattgaat tgcggaatat
    67081 cgatttgaat ccttatgcaa gattgggtat caatccagag caagttcggt tcttacaatt
    67141 attcctgatg tacatgttat ggacagaaga aaaagaagac tgtgaccaat gggtagcaga
    67201 aggtacgact cgaaataaca aagtagcact agaacaacca tcagatcaaa cagaatttca
    67261 tcaagaaggt agagaaattc ttgaaggaat gaagcaaatg ctggttgaat tggattggtt
    67321 ggattctctt tatttagtag aggaagcatt gactcaaatg gatcatcctg aacaaacgtt
    67381 agcagcgaaa ctctatcaag aagcacagct atcgagtcag caagaagttg ctgtggcatt
    67441 gggacatcaa tattataaag aaagccatga acgtccctat cagttggccg gttttcgcga
    67501 aatggaactt tctactcaga tatttatgtt cgatgccatc caaaaaggtg tccaagtcaa
    67561 agtattagat gagtcggatc aatttttgcg tctgcaattc caagaccatg tagaatatgt
    67621 gaaaaatgca aacatgacaa gtaaggacag ctatatcgtc ccacttatca tggaaaacaa
    67681 aacagtaacg aaaaaagtct taaaagaagc tgggttccgg gtaccaggag gcgcagaatt
    67741 ttcatccatg gaagaagcgg taaaagctta tccgagattt gccgagcagg catttgtgat
    67801 caaacctaaa tcaaccaatt acgggttagg tatcacgatt ttcaaggaag gagctagtct
    67861 ggaagattat caagcaggtt tagccattgc ttttcgtgaa gacagttcgg ttttagtaga
    67921 agaatttatg ccgggaacgg aatatcgttt ctttgtgatc gacggagaag tccaagccat
    67981 catgttgcga gtccctgcta atgttattgg tgacagtatc cgaacagtga aagaacttgt
    68041 tgaagaaaaa aatagtgacc ctttgcgtgg aacgaatcat cgtgcacctt tagaattgat
    68101 ccaattaggt gaattagaac aattgatgtt gaaagaacaa gggttgacga tcgaatcagt
    68161 tccccaagcc aatcaaattg tttatctaag ggagaactca aatatcagta caggtggtga
    68221 ttcgatcgat atgactgatg aattttctga agcttacaaa aaaatcgccg tttctgcggt
    68281 agaagcacta ggagctaaga ttagtggtat cgatttgatt ataccagata aagaaatcga
    68341 tcctacaact gataaaaaag catatgggat catcgaagca aatttcaatc cagccatgca
    68401 tatgcatgtt tatccttttg caggaaaagg cagaagattg acgatgaatg tattgaaatt
    68461 gttatatcct gaagtatttt aaaagaaaaa gcttttgaca gattgtccta tttgatgtca
    68521 atctgatcaa aagctttttt tgcatgtaaa aatttatgtg ttttttcgtt ttaaaataaa
    68581 cgatcccaga agcttttttt cttttttggt ttttcttttt cagctggcga agagttttct
    68641 tctgggtatt ttttttcgat atcaatcaca ggttcattta ctgcttcttt tgctgttaag
    68701 agcaatccga attcctcagg atttgcagtg acgtaatcgt tgactacagt gaaacggcta
    68761 ttgcttttcg ttgctagctg gatatattgg ttttggacag aaaggggtag agccccattc
    68821 aagagtatgg aagcatctgg atgttttttg agttctttta aaaagttttc tttgtttttt
    68881 ggttggatca tttcagcaac agtcatacta agatagcagc gttccctgaa tgtccctaaa
    68941 tatttatgct gttcttcagg gttcactaaa ggtgtaccat aaagtccctt atccaaatgg
    69001 ctttttacat catcttgtgc cataaaaaat accctccttc ttctctttgt ctttcttacg
    69061 attatagcat attcccaata atacctaaaa catatgaaaa agcggttgct tttgttcaac
    69121 gattcactta aaataagaat gaaaatcatt ctcaattaga aaggtggatt ggatgcgcta
    69181 cggacgacta gtagcattat tagttatttt aagtagtatt tcattgttca tcggagtatc
    69241 gaatgtacaa ttgtcagaac tgctccagtt agatgggcaa agcttacaaa tcttgctagt
    69301 gactcgtttg ccacgaacga tttgtttgat ccttgtggga gcgaccagta gtatttgtgg
    69361 gttgatcatg caacatttga cccaaaataa atttgtttca ccaacgactg cgggcacgat
    69421 ggatagtgcg cgtttaggta ttttagtggc tatgattttc ctacctggtg catccttgat
    69481 tgtccgatcc ttgacagcat tttgctttgc ttttgcagga acattgcttt ttttatccct
    69541 tacgcgattg ttcctccaga aaaatcaatt gatgcttccg ttgattggag tcatgttagg
    69601 gaatatcatt ggttcagttg ctactttttt tgcttatcaa ttccagttgg tacaaaatat
    69661 gacttcatgg cttcaaggga attttgcgac tgtgatacga ggaaattatg agttattgta
    69721 tgctgttgtt ccattgttgc tcttggtttg gctatttgct taccgattta cgatcattgg
    69781 tctgggcgaa tcgtttgcag taaatctggg aatagattac cagaagatgc agtttttagg
    69841 cattggctta gtatcattgg ctagtgcagt catgttgatc atggtaggaa gcattccttt
    69901 tatcggagtg atcattccga atcttgtctc tagaatatat ggagatcaag tgcacaaaac
    69961 aattggcgta actgctttag caggtagttt gttcttagta ttttgcgatc ttgtcgctcg
    70021 cgtgttgatt tttccttatg aaataccagt cagtgtgatc gttggaatca tcggtggggc
    70081 tatcttcctt tatcttctga taaggggacg acgatatgct taaaaaaaag ccatctattt
    70141 ttattggtat gcttgttctt gttttatttg ttacaggaat gtacttgacg atccatacat
    70201 atggaaactg gcattttgca tgtgcattga ggagtaagaa aatttttgca tttatccttg
    70261 tctcgctagc tgtcagcagt gccacaatca gctttcagac aattacgcat aaccagtttt
    70321 tgactccttc agtattggga cttgagtcgt tatatgtcct tgtccaaacg gtccttttct
    70381 tctttatcgg aggagtgacg atgcttcagc agacaggtac agtttttttc ttattgaacg
    70441 ttgggctgat ggtcgggctg agtctattgt tatttttctt tcttttgaaa aaaatgagag
    70501 cgaatctttt tttattactg atgtcaggga tgattttagg tacgcttttt ggtagtgtca
    70561 gtaccttttt acaagtcatc atggatccga atgaatatga tttgcttcaa ggcagattat
    70621 ttgcaagctt tggcaatatc cagagtcagt atcttttgcc tgcttctttg atcattatcg
    70681 gctgctggta cctgttattt cgatatcgac atgtgctaga cgttttccat ctcggaaatg
    70741 aacaagcagt aaacctcggg atagacacag atcgttttga atttttgatt ttatgttgtg
    70801 tcagtctttt gacagggaca tcaacggctc ttgtgggtcc agttactttt ttagggttta
    70861 ttgtcgcaaa tatcagttat cgtgtctttt ctacttatcg tcatggtcag ctatttatcg
    70921 gaagctttct ggtagctatg ctgtttctga caggaggaca gctcgcagta gagcagattt
    70981 tcggctggaa tacaacagtg agtgtcgtcg ttgaatttgt cggaggaatt tattttgtca
    71041 caaaattgat tcgcgaaagg aagagtatcc tatgattgat ttacaaaagg tcaataaact
    71101 gtaccatgga aaatcagtgg ttaaagatgt acagttaacg attcctgaaa agaaattgac
    71161 tgcttttatc ggtccaaatg gtgctggaaa gtcaacggtg ttgtcgatga tcagtcgttt
    71221 gataccaaaa gatacaggtg aaatctattt agaccataac gaagtaaagg cttggaaatc
    71281 caatgaatta gccaaaaaat tatcgatcct acgacaatcg aatgaaataa atgtccaaat
    71341 caccgtgaaa gaattagtag aatttggacg atttccttat acgaaaggaa aattgacgac
    71401 aaaagacgag gaaatcgttc aggaatcact ggaacacctt gggttagaag aaatagcgga
    71461 tcaatcgatt gacactcttt caggcggtca actccaacgt gcgtatattg caatggtgct
    71521 agcgcaagac acggattata ttttactgga tgaacctttg aacaatctag atatgaattt
    71581 tgcggttcaa atcatgcaga ttttaaaaaa tttagtacaa gaaatcggga aaacaattgt
    71641 tattgttctt catgatatca actttgctgc aagttatgca gacgaaattg ttgcaatgaa
    71701 agatggacag ttatttacgc aaggaacgac ccaagaaatg ataaaaaaag atgtattgga
    71761 tgaattatac gaaatggaca tacggatttg tgagattgaa ggccgcagat tctgtcttta
    71821 tttctaaaac taacattagg agagaagaga tgaaaaaatt agtagtaggt atcttgattc
    71881 tagcatcatt tggtttagca gcatgtggaa atagcaacaa caccagtcag gcagacacaa
    71941 aaaaaagcag cacacaaact gaaactacat tgacgataac agatagtaat ggagaccaaa
    72001 tcgaggtgcc aaataatcca gaaaaagtcg tcgtattcga caatggttct ttagatacga
    72061 tggatgctct tggtgttgga gataaggtag ttggagcagc tacaagcagc cttcctgagt
    72121 atctttcatc ctataaaaaa gtagaatcag caggtggaat aaaagaacca gacttagaaa
    72181 aaattaatca gcttcagcca gatctaatca tcatttctgg ccgacaaaga gattttcaaa
    72241 aagatctaag tcaaattgct ccgaccattt tcctttcttt agatgcgaaa aatccatggg
    72301 aatctttcca gcaaaatgtc actgctttag gggagatctt tggtaagcaa gaagaagcta
    72361 aaactcaatt agaggaatta tctagtgcaa tcgatcagac gaaaaagaaa gcagaagcta
    72421 ctgacaaaaa agcactagtc acacttgtga atgaagggca attatcagcc tacggatctg
    72481 gttctagatt cggtttcatc catgatttat ttggctttga acaagcagat gatcaaatcg
    72541 aagcatccac tcacggtcaa agtgtttctt atgaatatgt gctggaaaaa aatccggata
    72601 tcttatttgt agtagacaga acaaaagcta ttggtggaga cgacagcaaa gatgatattt
    72661 ctgccaatga actggtagca caaacgaatg ctggtaaaaa tcagcagatc atctcccttg
    72721 aaccagatgt ctggtattta agcgggggcg gtttagaatc aatgaaactg atgatcgaag
    72781 atgtgaatca agcatttaaa tagcataaat aacagaggat taaactctca tactatgtaa
    72841 caataatgtt tcttacattc ttaaatagca agagcctatc ctcaaagaag ttatcaaaaa
    72901 ccatccgtaa aatcgtattg atgattttac ggatggtttt tatttatttg agaaatcttt
    72961 tttcaacgtg aattcattat ctacatcata cgggttgatt ctagaatggg gagtggcaaa
    73021 aaatagtgtg atccattttt tcagcatcaa gatcgcctcc tttgatttga atcaaaggta
    73081 caaagcgaaa cttagataaa acttaaattt agatattttt attttgtacc gatctcttct
    73141 ttaaacgatg ttccatctgc tgcttctcgg caataagtcc actagactag aaaatatgag
    73201 aagctatttt ctgtccagcg ttcttattac tcaaagcaaa tcgcagttgt cacaatctct
    73261 tctaaacgat gttccatctg ctgcttctcg gcaataagcc cactagacta gaaaatatga
    73321 gaagctattt tctgtccagc gttcttatta ctcaaagcaa atcgcagttg tcacaatctc
    73381 ttctaaacaa tgttcaatca gctgaccttc ggtattagct caaagcactg atttcacaac
    73441 ctctatttag gcatgtgtct cagcaagcgg ttgatagttg atgatctgca tttttcgata
    73501 aaaatcggcg ggaagcttac tccaccgttt taataattga tagaaataac tctcttctgc
    73561 tttgatttta tactcgctta atatcaatcc aaaactattc gttttttttg aagctaattt
    73621 tttataaata tccaatgctt tggttttatc ttcattgaca aagagtgttt ttacttcaat
    73681 ataagaaccc tcgatatttt gtgtttcttc gataaaatag atgtttttta tatattcctt
    73741 catagtgatt cctccaaaga agtcttttat ttgataagtt tactctaccg aagagttgtt
    73801 aataatccgt gaacaaaaag taattctttt tccaatagtt gttaaaggtt ttttattttt
    73861 tatagtattt tttgttattt aagaaaggaa taaggttaaa caaataacag gttgcttttt
    73921 gggtcttttt ccgttcaaga aactgaacga agaaaaggga aagttgtctc ttttgtgata
    73981 agagaaatca taataaacga atgacttact ttccaataaa ttgagaacag tcagaaccag
    74041 acaaattagt tgcatctgat gaataaagtg attattctat gacatgaggt gatacagatg
    74101 aaattagaag tgacaaaaga agcacaagaa gtattgaaga ataaattaga agcagacgat
    74161 caacttttat tagatatcga aaacggtgac ggtccatttg cagaaagcca agtcagttgc
    74221 caattggata cggcatttcg attgatcatt gtcaaaaaag atacacaaac agatctaagt
    74281 ctttattctg tagtggctga tacaccagtt ggaccaatca aaatcaaaga cagtgcaata
    74341 ctttacatgg atgatccatc cacacttgct ttagaaccaa cttataatag tttacaatta
    74401 aaaggaccaa gcggcttgag aaaaggcaac ttgcaagttg ttcgaaaaga ctagagggat
    74461 aaaatgggaa aattggcgat catcagcgac ctacatgtgg acatcaataa attcggcgaa
    74521 tcagagctga tgcagctttg gcaagttttg caaaagcaca agatcactcg gcttcatcta
    74581 gccggagata cggctaataa agtagaccgt tgcctagctg ttgtcgaatt tttcgtcaat
    74641 aaaggattat ctacgacatt tcatttcggc aatcacgagt tggcagatgt gcccaatgaa
    74701 cagatgatgg accattttcc agacccacat tttttaaatg aacggtatat tgctttaaat
    74761 gagcagaccg ttcttttagg gatgaatggc tggtacgact atcagttttc cgaattgaaa
    74821 gattacgagg caatcgtacg aatgaagcgt ttgtattggt atgatcggtt catccagcgt
    74881 gggaaaacag atctcgaggt caatgcagaa atgcttgcag ctgcaaaaaa tttgctagac
    74941 cagctggaag caaaaaaact tgaggtgatt ttatccactc atttcgttcc taaacgggca
    75001 tttatcatgt atcaatctgc tccttatgag cgttggaaca aattaaatgc atttttagga
    75061 tcagaatcat tcggagaatt acttgaccgt tattcaaata tcaaacaagt agtttttggc
    75121 catacgcatc gtcgctttga agataaatcc atcggtcaca cgatttacag ctgcagacct
    75181 tttggttatt attatgaatg gcagctgacc cgagattttg tcttgaaaga acagttgcta
    75241 gacagctatg atcctatgaa attacgtgtc ctcttgcgtg cccatcaccc agcttttcag
    75301 gcctatcaaa cacaacattt gcaagaggaa tttgaacaag cgatgacaat cgttccgtat
    75361 tgagacagca ttagtaatgt gtaaaagaaa ataccttgta aaacataagg ataagtaaga
    75421 gcagtagatc catttatcgt ggatatgctg ctttttttgc ggaaaataat cagcgaatgt
    75481 ttatttgatc ggatgatttg taactcgcag agtactagat gcaagcgtgt attctttttt
    75541 tgaacgataa tcacaaaaaa aaatataata tacatttttt atttaattat aattaatatt
    75601 gattgaagtc taggcagtca agtcacattt tgatagatag gagggggact tacgaattat
    75661 tttaaaggct atgacagctg tatttctaga ttgtgtttgc atcaagttgc aataaaaact
    75721 agaaatcaaa tcgggctgat aatcatttat aactaatcga tacataggac caaatatagg
    75781 tctatgttct tttatttcat aagtatcgta aaacagaatt ttgctatgga ttaatccaat
    75841 cgactgatat gtttagtaaa taaagaaaga ggaatgtcaa tgatgaaaaa agaaatcgta
    75901 ttaacagcag caatgatgtt attcagcatg gtagcaagta cgacttttgt ttctgcaact
    75961 gaagtatacc caaaggaata taacacagaa ggaacgatta catttgaagc aggagatgag
    76021 ggtgtaactc ctcctgttga tccagagaat cctgatccca ataaacctgt cgatccatca
    76081 gatcctccaa gccctggaac aggaggggca ttatcgattg attatggatc aaaattcaaa
    76141 tttgggactc aaaaaatttc tactgcggat aaaacgtatt atgcagctgc tgatgtgatg
    76201 aacgatgggt ctagaaaacc gacatatgtc caagtgacag ataggagaag taccttatct
    76261 gggtggaaat taagtgtctc tcaaccagaa cagtttaaaa ctgccagtgg ggatgaacta
    76321 gttggagcac agctgaaatt tacgaaaggg caggctgttt ctttggttga tccaacatat
    76381 acgccgcaaa cggtgaattc tgaattaacg ttgacaccgg gaggaaacaa tacgttagca
    76441 attaatgcta aatcaggaac aggtgtgggg acttgggtct atcgatttgg tgcaaatgaa
    76501 aatgaaaatc aagatgcggt acagctttcg gtacccggta aatctgtcaa gttagcgcaa
    76561 caatattcca ctaaattagt ttggacatta gaagatacac ctaacaacta gtttactgaa
    76621 aagaactgtt aaaaataaat acgtagtcat attgtcttgc gaggtaatcg agcaaaaatt
    76681 gtcaaaggct aggctaaatt tgtttggata cgaatagttc atctaggaat ttaacgatca
    76741 ggaggaaaag atatattgaa aaagaggagg atcgtgctca ttttaagcag tctcttagtg
    76801 actaatatct ttccgatcat agggtactct ttggaattga atcagttgga gcatggaaat
    76861 agaagagacg aagaaagcaa actcacttcg acattcgaca gtttaataga atccaaccag
    76921 acacaagaaa gcagtgagga tttaagtatt tcgagtagtg gagagaccac tgacaacgta
    76981 gaagctgagg gttcggacaa acaaggacta gaagatgcac caatttctgc ggttgagctg
    77041 cctgacgatc ccaatattat ttctatcgat aaaatttttc aaacacctat cggtactagc
    77101 acgtccatat tggaaaatgg gaagttactg cagttgaacc cagcagaaag gtctcaaaga
    77161 ggagctattt ggtcaaataa gaagattagt ttactctcgg attttacatt taaatcttat
    77221 ttatacttag gaaatcaacg agatagagcg ggagatggca tgacctttac attgactggc
    77281 gatcctagaa tggctagtaa tcccagtcaa gttattggat cgccaggtat gggaattggc
    77341 tcatattcta ctcgttctgg ccaaccttac attgcgaatg cgctctcgat tgagtttgat
    77401 acgtataaaa atagtggttc ttctgatcga atggatcgag agataactgc tgataataga
    77461 gggcatggac atgtcgcttt tgtcacgcct aaaccaaata ataataatta ttctggagag
    77521 catactggcg tgacggtagc tcctacattt ctttctaatg gcacatggcg cttgttaata
    77581 attaaatggg acgcggagca aagaagtctt acttatgatt tggaaggtgt cggtcgctct
    77641 tctcggatta tacctgatct cattaggcag tttggttcta cagaagtaaa ttgggggttt
    77701 acttcttcaa caggtacttt ttttcaagaa aatgctgtcg ctgtcacgcg acttccatcg
    77761 aatgtcacat caacagctga tgtaaaagtc aacgatagtg attatggggc catcgctgaa
    77821 gctggaggaa acgataagat aactatcaga aatacattga aggtcgaggg ggattttctt
    77881 gaatataaga aaatgcagac tagtatcgac ctcccacaag aattaactat tcccgagcat
    77941 atcttgatca atggaaatca aattgatgcc aaagatatct tgataaccgg aaatcgagtc
    78001 acgctaaatc tgacagatta ttttattgct ggagatacgt taataatcga attggagaca
    78061 actttgcagg aagtaattcc tgaaaaagta ctcactatgc attttgaata ccttgaaaac
    78121 gggaatttga ttgagcaatc gaatgaaata aacctaaaga tcgcaaagct gaaggagata
    78181 gatatccatg tttattataa agataaagac agtcagattg atattgctga aatgaaaaca
    78241 atcactggga aaataggaga gaagtataaa gaaactccta ttgatattga agggtatgtt
    78301 tttgactcgg attcagcgaa tacagaaggc atcttctccg aaaatacaga ggatatctat
    78361 ttttattaca gaaaaggcaa actttatctc tcaactgctc ctcaatatgt caattttgga
    78421 aaacataaaa tatccagtag accattaagt gaattcggac agttttcagg tgggttgaaa
    78481 attatagatg aacgggcttt tggaagttgg aaattacaat tgaaacaaga gaaagttctt
    78541 acaaatggag attttgagct tccagaagct ctttcctttg ttacctctga aaatacaacg
    78601 gttataggga catccgctgt tacgattttc gaaagtgatc aaaagggtga aagcgatttg
    78661 tcctctcttt tagattctac agctcatcgt ggaatcagaa tagatattcc tgtagaaaac
    78721 caaagaatcg gaacctttga ggggaaacta tcttggatac ttgcagatgt cccaggaaat
    78781 taacaggaag agaagaatat aacaaaatta ttgagtttca agaagggcac aggtaccata
    78841 ggctcttgtg tcccacagag acaagatttt gttatagtct tctcttacat atgattaaag
    78901 gagcgatttt cttgagacca aaacaacaat tatttataac actcctagtt attttagggg
    78961 cactttttaa caatatatca gtgtcagcta gtgcatttaa tttttcagtg acgccgataa
    79021 cttcagagaa tcaaatcgac aagagaaaaa cttacttcga tcttcaactt gatccggatc
    79081 aggaagtaga agtaaaagcg gaattgagaa atgatacaga aaaagaagtg aaaatcgata
    79141 tttctgtgaa tagcgcaacc accaattcaa atgtgatggt tgaatacgga aaaaacgaga
    79201 ttgaaaaaga catgagcctg atctttgatc tggtagatta tgtgagctat ccacagatag
    79261 tgacgctaaa acctaaaagt gtccaaaccg ttgcttttca tgtcaggatg ccgaatgagc
    79321 gatttgatgg tgtattggct ggtgggatca cattccaaga aatccagacg gaaaaggacc
    79381 aaacagaaac taaggatcaa agcttatcga ttgagaatga atacacctat attattgctt
    79441 tgttgatgca acagacactg aacgaagttg ctccgaacct tactcttcat gaagttaaac
    79501 cagatcaaat caatgcaaga aatgtcatct tagcaaacgt tcaaaatgat caaaaaacct
    79561 atatcaatca agtagttatt gaaacaaaaa ttacaaaaaa aggacattct gaagttttat
    79621 atcaagagga aaaagaagga ttgcagattg cgccgaatac aaatttttct tttccaactg
    79681 ctttaaatgg tcaaccgcta accccaggtg aatatcacct tacaatgact gttttaggaa
    79741 atgaaaatga aaatggaaaa ttttcgagaa aaaaaggaaa tactacgatc aactatacca
    79801 atcaatgggt atttgaaaaa gattttacaa tagacggaaa agtagccaag gaattgaaca
    79861 cgacggatgt tacgattaaa aaagacaata attggattta tatcttagta gcttcacttt
    79921 tcttattgtt tattttatta tgcatacttt tgtttgtttt gagaaaaaaa gaagagaaag
    79981 aaaagtaagg ttaagataac aaatagtaaa tttttattat tgtaggatgg ttgggctctt
    80041 tttataacaa tataaaatat accattttat taataaaaat gcatactagt aaatgatata
    80101 attctaataa caggtttgat cgcgagaaag gccaaataaa acgctctcca aaatgttaaa
    80161 aaaaagacag gacgatgtat attatacaaa caagaatcgc tgacaacagt gactcggatc
    80221 caggaaatca gttttatccc cagctagttg gtgaatgcat ggaaagtaat atacgtagaa
    80281 agagctgatg actaatgaat tatgagtttt ttttaagcaa agaagatcac agaagttatt
    80341 cattacttaa atatttagaa gcaagctcaa atttatcaga gtcaatatcg aatgttcaag
    80401 aagagttgtc gctatcgaca tttctcttga aaaaaacgat cgataagctg aaacatgatt
    80461 tacaaaagtt cgatctagag aaaaatttgc gagtaaccgt cagtgaattg gatatatgtc
    80521 tggaaattaa tggaaaatgt tctagcaaag ctctgttatc tcgttatata acggattctt
    80581 tatctatgaa aatggtattg gctttctttc aggaaaaata tatctcagta gaaaattttg
    80641 ctaaacagca tcacgtgagt tattctgtgg cttataaagt attacaaaga ctaaaaagaa
    80701 atctaaaaaa atatcaaatt ttttttgaaa agagaaagtt g
//
LOCUS       DASHWW010000006        79402 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.006, whole genome shotgun sequence.
ACCESSION   DASHWW010000006 DASHWW010000000
VERSION     DASHWW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 79402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.006"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            591..1280
                     /locus_tag="U2R64_000491"
     CDS             591..1280
                     /locus_tag="U2R64_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8917337.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="U2R64_000492"
     CDS             1267..2475
                     /locus_tag="U2R64_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8917338.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="U2R64_000493"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="U2R64_000493"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEM8917339.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="U2R64_000494"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="U2R64_000494"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEM8917340.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="U2R64_000495"
     CDS             complement(6578..7273)
                     /locus_tag="U2R64_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEM8917341.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="U2R64_000496"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="U2R64_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEM8917342.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="U2R64_000497"
     CDS             complement(8472..8663)
                     /locus_tag="U2R64_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HEM8917343.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="U2R64_000498"
     CDS             complement(8684..9574)
                     /locus_tag="U2R64_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEM8917344.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="U2R64_000499"
     CDS             complement(9561..10328)
                     /locus_tag="U2R64_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8917345.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="U2R64_000500"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="U2R64_000500"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEM8917346.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="U2R64_000501"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="U2R64_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEM8917347.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="U2R64_000502"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="U2R64_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEM8917348.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="U2R64_000503"
     CDS             14899..15282
                     /locus_tag="U2R64_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917349.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="U2R64_000504"
     CDS             complement(15450..16208)
                     /locus_tag="U2R64_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HEM8917350.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="U2R64_000505"
     CDS             complement(16226..17044)
                     /locus_tag="U2R64_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEM8917351.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="U2R64_000506"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="U2R64_000506"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEM8917352.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="U2R64_000507"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="U2R64_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEM8917353.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="U2R64_000508"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="U2R64_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEM8917354.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="U2R64_000509"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="U2R64_000509"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEM8917355.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="U2R64_000510"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="U2R64_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEM8917356.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="U2R64_000511"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="U2R64_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEM8917357.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="U2R64_000512"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="U2R64_000512"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEM8917358.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="U2R64_000513"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="U2R64_000513"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEM8917359.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="U2R64_000514"
     CDS             27086..27385
                     /locus_tag="U2R64_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEM8917360.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="U2R64_000515"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="U2R64_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8917361.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="U2R64_000516"
     CDS             27973..28209
                     /locus_tag="U2R64_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEM8917362.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="U2R64_000517"
     CDS             28352..30325
                     /locus_tag="U2R64_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEM8917363.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="U2R64_000518"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="U2R64_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEM8917364.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="U2R64_000519"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="U2R64_000519"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEM8917365.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="U2R64_000520"
     CDS             33204..34496
                     /locus_tag="U2R64_000520"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEM8917366.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35232..36095
                     /locus_tag="U2R64_000521"
     CDS             35232..36095
                     /locus_tag="U2R64_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8917367.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36224..37846)
                     /locus_tag="U2R64_000522"
     CDS             complement(36224..37846)
                     /locus_tag="U2R64_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8917368.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38095..38616
                     /locus_tag="U2R64_000523"
     CDS             38095..38616
                     /locus_tag="U2R64_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEM8917369.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38802..40532)
                     /gene="spxB"
                     /locus_tag="U2R64_000524"
     CDS             complement(38802..40532)
                     /gene="spxB"
                     /locus_tag="U2R64_000524"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEM8917370.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40697..41515
                     /locus_tag="U2R64_000525"
     CDS             40697..41515
                     /locus_tag="U2R64_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HEM8917371.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41618..41815)
                     /locus_tag="U2R64_000526"
     CDS             complement(41618..41815)
                     /locus_tag="U2R64_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917372.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41984..42562
                     /locus_tag="U2R64_000527"
     CDS             41984..42562
                     /locus_tag="U2R64_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEM8917373.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42657..42794
                     /locus_tag="U2R64_000528"
     CDS             42657..42794
                     /locus_tag="U2R64_000528"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917374.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43607..44110)
                     /locus_tag="U2R64_000529"
     CDS             complement(43607..44110)
                     /locus_tag="U2R64_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEM8917375.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44469..45494
                     /locus_tag="U2R64_000530"
     CDS             44469..45494
                     /locus_tag="U2R64_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8917376.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45841..46719
                     /locus_tag="U2R64_000531"
     CDS             45841..46719
                     /locus_tag="U2R64_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HEM8917377.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47195..47311
                     /locus_tag="U2R64_000532"
     CDS             47195..47311
                     /locus_tag="U2R64_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEM8917378.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48239..48577
                     /locus_tag="U2R64_000533"
     CDS             48239..48577
                     /locus_tag="U2R64_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917379.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48671..48901
                     /locus_tag="U2R64_000534"
     CDS             48671..48901
                     /locus_tag="U2R64_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917380.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49301..49672
                     /locus_tag="U2R64_000535"
     CDS             49301..49672
                     /locus_tag="U2R64_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HEM8917381.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49946..50638)
                     /locus_tag="U2R64_000536"
     CDS             complement(49946..50638)
                     /locus_tag="U2R64_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8917382.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50641..51426)
                     /locus_tag="U2R64_000537"
     CDS             complement(50641..51426)
                     /locus_tag="U2R64_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8917383.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51663..53063
                     /gene="lacG"
                     /locus_tag="U2R64_000538"
     CDS             51663..53063
                     /gene="lacG"
                     /locus_tag="U2R64_000538"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEM8917384.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53088..53405
                     /locus_tag="U2R64_000539"
     CDS             53088..53405
                     /locus_tag="U2R64_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEM8917385.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53418..55091
                     /locus_tag="U2R64_000540"
     CDS             53418..55091
                     /locus_tag="U2R64_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HEM8917386.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55105..56736
                     /locus_tag="U2R64_000541"
     CDS             55105..56736
                     /locus_tag="U2R64_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HEM8917387.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57608..58798
                     /locus_tag="U2R64_000542"
     CDS             57608..58798
                     /locus_tag="U2R64_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HEM8917388.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58932..61121
                     /locus_tag="U2R64_000543"
     CDS             58932..61121
                     /locus_tag="U2R64_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8917389.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61118..62911
                     /locus_tag="U2R64_000544"
     CDS             61118..62911
                     /locus_tag="U2R64_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEM8917390.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            63111..63425
                     /locus_tag="U2R64_000545"
     CDS             63111..63425
                     /locus_tag="U2R64_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8917391.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63446..63823
                     /locus_tag="U2R64_000546"
     CDS             63446..63823
                     /locus_tag="U2R64_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8917392.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            63833..64606
                     /locus_tag="U2R64_000547"
     CDS             63833..64606
                     /locus_tag="U2R64_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917393.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64628..66031
                     /locus_tag="U2R64_000548"
     CDS             64628..66031
                     /locus_tag="U2R64_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEM8917394.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            66213..67397
                     /locus_tag="U2R64_000549"
     CDS             66213..67397
                     /locus_tag="U2R64_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEM8917395.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67394..67684
                     /locus_tag="U2R64_000550"
     CDS             67394..67684
                     /locus_tag="U2R64_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917396.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67681..67902
                     /locus_tag="U2R64_000551"
     CDS             67681..67902
                     /locus_tag="U2R64_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917397.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            67944..68723
                     /locus_tag="U2R64_000552"
     CDS             67944..68723
                     /locus_tag="U2R64_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEM8917398.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            68790..69284
                     /locus_tag="U2R64_000553"
     CDS             68790..69284
                     /locus_tag="U2R64_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEM8917399.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            69340..69978
                     /locus_tag="U2R64_000554"
     CDS             69340..69978
                     /locus_tag="U2R64_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917400.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            70050..70445
                     /locus_tag="U2R64_000555"
     CDS             70050..70445
                     /locus_tag="U2R64_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8917401.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            70429..72882
                     /locus_tag="U2R64_000556"
     CDS             70429..72882
                     /locus_tag="U2R64_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8917402.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            72879..74906
                     /locus_tag="U2R64_000557"
     CDS             72879..74906
                     /locus_tag="U2R64_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917403.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            74903..75925
                     /locus_tag="U2R64_000558"
     CDS             74903..75925
                     /locus_tag="U2R64_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEM8917404.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            75942..76871
                     /locus_tag="U2R64_000559"
     CDS             75942..76871
                     /locus_tag="U2R64_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8917405.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            77116..77232
                     /locus_tag="U2R64_000560"
     CDS             77116..77232
                     /locus_tag="U2R64_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEM8917406.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            77248..79167
                     /gene="tet(M)"
                     /locus_tag="U2R64_000561"
     CDS             77248..79167
                     /gene="tet(M)"
                     /locus_tag="U2R64_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEM8917407.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            79265..>79402
                     /locus_tag="U2R64_000562"
     CDS             79265..>79402
                     /locus_tag="U2R64_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEM8917408.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QK"
BASE COUNT        25249 a        14129 c        15680 g        24344 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca ccgcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaacaaa cggtgttcaa aagcttgcat ctacggcact aagcccaatc
    34681 agatgaaaaa tatggagtgc tatttttatc tgattgttct tactgcttga tgcagagcag
    34741 ctttttcaca acctctccac taaacggtgt tctcctgcca actcctcggt cacaagtcac
    34801 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagctaaa
    34861 cggcaggctc acaacctctt ggtaaacggt gttcaatcag ctgaccctcg gtattagctc
    34921 aaaaaacggc aaaatatgag gaactatttt ttccgttttt ttctctaata ctcaggtcaa
    34981 aacgctgatt tcacaacctc tgattcacgg tgttccagaa gtagcttcta cggaaataag
    35041 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    35101 tgaccacttc tgtcacaacc tcttattttg attagaactt gcgaaaataa accggttaaa
    35161 gtgtgtctag cgcaagagat ttgctataat agacgataag ggtaaaatgt aacgagaagg
    35221 ggttgaaaaa tgtgtatcaa attgtaacag attcttgttg tgatctgcca taccatgtat
    35281 tagcaaaaga aaaagttgat tttttatcaa tgaatctcca attgaatgat caagagttag
    35341 tagatgacct cggaaagaca ttcaattatg accgctacat gaatcagctg aaaaatggtg
    35401 cgatgcctac gacatcacaa atcaatgttg gccgatattt agaatttttc cgttcttatg
    35461 cggaaaaaca gattcctgtt ttatatgtgg ctttttccag tggattaagc ggctcttaca
    35521 gtagtgcgct tcaagcggtt gaattgctga aggaagaata tgaagaccct gagatctatg
    35581 tttttgatac aaaagctgca agtattgggg aagggctttt agtattggaa gctgtaagat
    35641 tgaaaaaaga aggtaaaagc atcgaagaaa ccctagagtg gctggaaagt aattatttga
    35701 aagtccattc atgggtaaca gtagacgatc tgaaatatct agaacgaggc ggtaggattt
    35761 ccaaagcaag tgctactctt ggcagtctat tgagtgtaaa gcctattatt acggtggata
    35821 aagaaggaag gctgacgaat gttgacaaag ttcgaggaag aaacaagtcg atccagacaa
    35881 tcgtcaatga gacggtaaaa acaatcgttg caccacttga tcaaatcgtt tatgtggctt
    35941 acgctgggga tctagagagc gcggagaagg caaaacggct tttggaagag cagataaaga
    36001 tgaaagatgt gaagctttat cccttaggac caacgatcgc cagtcacaca ggctatggct
    36061 gtatcgcgat tttttcgatg ggaatcagtc gataaaagca gtaactcatt ctgtaaaaaa
    36121 gcccagaaat tgattgtaac aaaaacagcg actcttaaaa gatagatgag catcctatct
    36181 cttagaggtc gctgtttttt tattttttaa gctaaatagg ccattatgcc cataactcgt
    36241 tcaattgttt ttgaatatct gcattttcca aaaattcatc atatgtcgta tcagctcgat
    36301 cgatcacacc tttatccgaa acggcaatga tgcggtttgc caatgtttgg ataaattgat
    36361 ggtcatgtga cgcaaataag attgagccag taaatgccat caagccgtca ttcaatgctg
    36421 tgattgattc taagtctaaa tggttcgttg gatcatctaa tacaagtacg ttagctttcg
    36481 aaagcatcat ttttgaaagc atgcaacgga ctttctctcc accagataaa acattcactg
    36541 gtttcaatac ttcttcacca gaaaacaaca ttcttcctaa gaagcttctt aagaaggtgt
    36601 tatcatcttc ttctttactt gcatattgac gcaaccagtc taaaatcgtt agatcagtat
    36661 cgaattcttt cgttgtatcc tttggtaaat aagaattact tgttgtcaca ccccaacgta
    36721 ctgttccagt atctggcgta atttcaccca tgataacttt gaatagcgtt gttgttgtta
    36781 tatcattttc tgcgacgaaa gcgaccttgt cttctttgct caaattaaaa gatatatcat
    36841 ctaaaatttt ctttccatca atcgttacac ttacattttc tacctgcaat aagtcgtttc
    36901 caatctcacg ttcaggtttg aatccaacga atggataacg tctagaagaa ggttggatat
    36961 cgtctaaagt aattttttca agcatttttt tacgtgaagt tgcttgtttt gattttgatg
    37021 cattcgcact aaagcgggca ataaattctt ggagttcttt gatttgttct tcttttttgg
    37081 catttgcgtt tgcttgaagt ttagccgcta gttgactaga ttccaaccaa aaatcataat
    37141 ttcctacata aagtttgatt ttaccaaaat ctagatccgc catatgtgta catactttgt
    37201 tcaaaaagtg acggtcatgg gatacaacga tcacagtatt ttcaaaattg atcaaaaatt
    37261 cttccagcca attgatcgat tggatatcca gaccgtttgt tggttcgtct agcaaaagaa
    37321 catcaggttt accaaatagt gtttgtgcta ataacacttt taccttttgt ccaccagtta
    37381 attcactcat ttgctgatgg tgcaattctt cagggatgtt cagaccttgc agtaaaacag
    37441 ctgcttctgg ttcagcttcc catccattaa gctcagcaaa ttctccttct aattcagctg
    37501 ctcgaatacc atcttcgtca gtgaaatcct ctttcatgta aatcgcatct ttttctttca
    37561 gcacttcata cagacgcttg tgtcccatga tgactgtttc aagtacagta tagtcttcat
    37621 agtcgtaatg gttctgtttc aatacggcca tccgttcatc tggtcccata gtaacggaac
    37681 ctgtggaagg ctgcagatcc cctgataaca ctttaaggaa cgttgattta cctgcaccat
    37741 ttgcaccaat caagccatag cagtttccgg gggtaaattt aatattcaca tcatcaaata
    37801 gtttgcggtc tgaaaagtgc aaactcacat catttacagt aatcaatttt tttcctcact
    37861 tttatcatta ttagttttga caagtcttat agaattatat aggggaaagg taaaagattc
    37921 aaggcaatcg aacattcttt gtgtttcacg tgaaacagaa tgaaaaaaat aaaaataaaa
    37981 gcggagcgaa aatagctact ataggattta ttagtttgca acagcataat ttttgacgtt
    38041 atttataaga gggagtacta taaaactgta aaagaaatga aagaaggatt gaaaatggat
    38101 gaaaaaagaa ccatcgactg gggctcattg attttgggaa ttttatttgt acttgtctca
    38161 ttgttatcat ttcaagaccc tgtcggaaat ttagttgcaa ttgtagtagt ctttgcgatt
    38221 tttgccttta ttaaagggat atttgaactg tttgtacgga acagattaaa agagctaaca
    38281 ggatataaag gaaagatgcc cttaataatc gggatcatcg atattctagt tggcgtcttt
    38341 ttcttattca atattggtgc aggagtcgca gcattgcctt ttgtttttgc agtatggttt
    38401 attgctgatt cagttttagc gttatttact gctgacttgg caagaggagt aagtgaagga
    38461 tattattggt ttacgatcat cgtcaatatt ttaggaattt tattaggaat tttcttattg
    38521 tttaatccaa tttcttctgc gttgacatta agctttttag ttggattcta ttttatgtta
    38581 tttggtatca cacatatcgt ctatgcattt agataagtaa aatcaaacaa ataaaaaagc
    38641 cggcttccga ttacagtttt actgttgtaa ttggaagccg gcttttttat catggacaaa
    38701 tatgcacgag gtgattttta ggtgtcgaga caaatttatg caaaaatgtg agaagctata
    38761 tacacaaatt ttatcttaat actcgaagca tagcgcagtt gtcacaacct cttttcatat
    38821 aattcattca atactggcaa atcatggact tcatattttt ctttgaatgc ttggatttct
    38881 tcttcagaat attttcttgg atctaaatgc agatcttcta ctggcaatgg gcgcttgtta
    38941 ttgatcttca catcgattac tacaggacga tctgattttg cagctgcatc aaaggcaaat
    39001 cgaagttgcg agtattctgt gactgtaaag ctatttgccc cgagcgcttc tccaacttta
    39061 ccgaaatctg catcttctaa aaatacacca aatttctttt gttccgtatc ttcttgttct
    39121 gcttcgatga aaccaaaaga atcattcgaa aagacaacat taataattgg aagctgatat
    39181 ttgacttgtg taatgatatc ttgcatgacc atagcaaacc cgccatcacc acttaaggta
    39241 aatacttgtt tttctgggta gcttagttgt gcggcaattc ctcctggcac accattaccc
    39301 atagttgcga accatccaga tgtcgtatgt ttttgtttac cgttcatatt caataaacga
    39361 atagaatgga tagtcgtgtt accgacatct gtgacgaaaa tcgcatcgtc ttcagcaata
    39421 cgattgattt ctttatagac agcctctgga cgaatcggtt cttcctctcg atcttcaaaa
    39481 gatttcaacc aatttaccca tttttcttta ttttcttgat ttgctaggta ccagctatca
    39541 gcagggcgag catcccctaa ctcgacaagt ctttgcaaag ctgtgtttgc atcaccgagg
    39601 atcgacaaag atgtttcatg gcgtcgtcca aattttgacg catcgatatc gatttggata
    39661 aattcagcag ttggattaaa aaatgcacgt ccaaatggga agtcgctacc gacaaataag
    39721 atcagatcgg cttctgccaa tgcttcattt ccgggtttag tagcgacacg tccagcaaaa
    39781 ccaagaaagt tttcataatc atcaggaata attccttttg ctagaacgga agcgacaaca
    39841 ggaactgaaa aatgttctga gaattctttg atttgcggaa atccgtttcg cgttccttga
    39901 ccaacataaa gaactggttt ttttgctttt tcaagataag gcaaagcagc tagcaaatct
    39961 ttttcttctg gtaatatcac acttgttttg tgagtgtgag cggtggagaa aggttgttcg
    40021 tcaatttctt caaaaccaag atcaacaggg atagtcacga tagccacgcc tttatgctca
    40081 taggcggctt taatggcttc atctactaca tgcggaagac tttgtggtgt catgactgta
    40141 cgattgtata cgctaacatc tgcgaaaata ggattttcat ttagttcctg gaaagagtta
    40201 tagttcatgg atgtagaagc aacttgtcct aagaacgcta ctagaggcac atggtccatc
    40261 tgtgcatcat acaaaccatt gatcaaatgt gtcgcaccag gtcctgcaga gccgaagaca
    40321 gcgccgactt tccccgttaa ttttgcatct gcagcggctg cgagtgcgcc gacttcttca
    40381 tgacgaactt gaatgtagtt gatttcggtt ttttcttgat atagcgcatc cataattgaa
    40441 ttgaaagatc ctccgggaat gccgtaaata tggtcgatac cccagctttc aagaactttt
    40501 accattgcga ttcctgcatt gatttttgac atggtgtttc actcctttag caatgatgat
    40561 acataaattt tttgtatcta gagtatagaa ctttttatcg aaaatcccaa ctaattcgtc
    40621 ttttcacaaa aatgtagtca tgtttttggg aatatgctag agtagtacat agatagattc
    40681 aagagagggg aatggcatgg ttgaatggct attgagactt gaaccttggc agcaagcact
    40741 tgctgggaca gcttttactt attttatgac agctcttggt gccgggttgg tttttttctt
    40801 taaagaaatc aaaaaagaag tgctaaactt gatgttagga tttgcttctg gtgtcatgat
    40861 tgctgcaagt ttttggtctt tgttagatcc ggctattaca aaagcagaag aaaatggaga
    40921 tattgcttgg ctagttgtaa gtattgggtt tggtttaggc ggtgtgtttt tatatatggc
    40981 agataaaaca ctgccccata tgcattttgg accacaacat gaagcagaag gattgcctac
    41041 ccatttaaaa cggacgatct tgcttgtttt ttctattaca ttgcataaca ttcctgaagg
    41101 tttagccgtg ggggtagcat tcggtgcagc agcaactgcg gataatccga cagccgctat
    41161 attagccgct gtttcggtgg cgctaggtat tggtatccaa aacttcccag aaggagcagc
    41221 tgtatcaatc ccgttgcgac aagaaggtct gagtcgtaaa aaggcctttg tttacggaca
    41281 agcttctgga atcgttgaac caattgctgg agtgattgga gcgctactag taacgaaagt
    41341 ggagctgctg cttccttatg cacttgcttt tgccgcagga gcaatgattt atgtcgtggt
    41401 ggaagaattg atccctgaag cacagcagac attgtccagc aaacgtcatt ttgcagtttt
    41461 tggcgtcatg agtggattta tcattatgat gattttggat gtggcattag gataaataaa
    41521 aaaaatatat atgatatatc aaatagggcc gcgaacttat atcgcgaccc tattttttta
    41581 gtaagttata tcataatgaa gtgaatggta tcatacatta ataatagttt tttctatgtg
    41641 tatttccttt gatccagcga acaagccaga tgataagtgc gattgggatt agaactttga
    41701 ccgcaaacca taaaagcccg cttaggacac tgacaaaaag actgatgacg aagctagctg
    41761 caattagcac taaaagaacc atgaagatat ttaagaacat atttttttga cgcatacaaa
    41821 accctcctct tgttcattct ttactataga aaaagtataa cagggattgt ttaaaaacac
    41881 ctccaactga agactgattt ttacttcatc tacttaaatg atcaaacaat tgctttttct
    41941 ctggtttatc atctaaaata gagcggaaaa ggaggagaat atcatgccta aaaatcgtct
    42001 tgaagcattt acagatgctg taatcgcgat tatcatgact attttagttt tagaacttca
    42061 tgaacctaac ggagacacgt gggaggcgct cgctgcatta ggttaccgat tttttatcta
    42121 tattgtcagt tttatcattt tagcgattta ttggaacaat catcatcatt tatttcaagt
    42181 tgtacataag ataaatggac gggtcttatg ggcgaacagt ttctttgttt ttgcgctttc
    42241 gctttttccg tttgcaactt catggatcag tgagtacatc aatagcctgg ctccagaaat
    42301 gacttatggt tttgttacct tgaccgctaa tattgcgtat tatatcttgg caaaagaact
    42361 tgtcaaagca aataaaggcc acgagaaagc attgaaggcg atgttgaata attacaagaa
    42421 atcgtatcta tcgattggtt tgaatgtgtt aggaattgtc ttagggtatt tagtagcgcc
    42481 agtagccgtg ctgatcgcaa acatcgtgat tctagctgct tggatcatcc caagtcgtac
    42541 catcgaatca caatatcggt aaaatgatcc gtgtttaaaa tttaagagaa aaatatagaa
    42601 aaaataaata aacgatcaaa tatccgagtg atactagtat tcaaagaggg atgcagatgg
    42661 atcaaaaaag aattcatgta ggactgatta ctagttttgt cacgatgctt atttatttgg
    42721 atcaaggtca tttgacttgg acagtagttg gtgtcgtagg atttttgaca ttattcacag
    42781 caataaaaaa ataaacatct ttatgtaatc tgatgttcta tctatttaag aaaagcatgt
    42841 ttacagcagt atgattctgt tgtaaacgtg tttttatttg tggaaaattt aatttttaga
    42901 aaagtgtatc gaaaaataga tagttagttt ttccacagtg gataacttcg taagagataa
    42961 aaataaaaaa ttagtcaaag aagggcgtat agatttcttt tgataggaga tatacaacag
    43021 aaatgaataa atattaacgt gttttcaaac agtataaaac ggtgtggttt ttggaataaa
    43081 aaaataacat atctcatttt acgcttttgt tattttatac ttaaaaaata acgacacaga
    43141 aaataccgtg tctcagattt ctctactact tctaaaaact actgtttttt tcctttgaaa
    43201 tgccttcaaa aagtaggatc aggcagaata tactggcaga atcaaggaga agggagccta
    43261 aataaggaga aaaaccatag aaaatataaa gtaattactt ataaaacaag ctttttatag
    43321 aaaaataata tacctgagta gggtataaat taagacggaa ttcctttcta gattgagata
    43381 ttgactagga agaatgttaa gattttaagc ctttaagcta aaaaaaaacc ctttttgtta
    43441 aataagggga atatagcctg tcagtttcaa actgcaagtc gtcctgctgc aataatatag
    43501 tagattagag atgaaaatag atttttttaa accaatgact gaataaaaag accgtcatag
    43561 atacacattg gaatgtgtct attacggtct ttttttacga acgattttat tgaagacgga
    43621 cagttcgggt caaaaataaa aaagctacga tcagaaataa gaataaaatg tatcccaaaa
    43681 taatggctag acggtctaac ttatttgtcg atagatgttt gtttagaagt tgataggccc
    43741 ataaacctat cagtcctcct gttgtattag ttatcaaatc agtgatgtcc gctacgccaa
    43801 taccgaatag gaattgaatc aattctgcca agaagcttac aaggaaaata atccctaatt
    43861 ttttagaaaa agaaagtctc ttgaaattga cattcaaaag caccccaaaa ggaaaaaaga
    43921 caatcaagtt ataagtggtc tcacgtaata ccgtcgtatt ttcaaaagaa aaagtagaaa
    43981 aagggacgag attgacattg ctgtaagaat aagtgagaaa ttgtggaaga ttaaatgata
    44041 gcttgaataa aatcaaccat aatagaaaga ataaataaat ccctaataaa aattttgata
    44101 cataccgcat agacatctcc tccatttaaa aagtatacca tcgaaaaccg ctgaaaaatc
    44161 ataaaaaagt atgaagttta aggaccaacg tagttatcgt acgaaaatta gaagcttttt
    44221 tttgttggga atccggtttc tttaacaaag ctaagatagc gagttgcttg gaaaagttgc
    44281 tatctttttt ctgtcaaaac gactcggaat gttcgttttt tgttctaatt tctccaagtt
    44341 gtttactttt tgatactaag tttatgaaaa atcaagaaat agttgttata ctaggtaatg
    44401 ctgacaaacg ggattggcat ttcatcttgg ttcagctttt tttccaatta ctaggaagga
    44461 gggatagatt gttcaagact tattttcgtt tcaataaaat acaagataat ccttttcgta
    44521 tcatgaatct gatgctactt atctttattg tattatggtt aggttacata aatcatgatt
    44581 ttttgatttc aagtttttca tcattaggga tctttacttt tttctattat caaaacatac
    44641 cgatgaaata tttgctgaaa cgtatgtttc tgatcggttg cggactgttg gttgctttcg
    44701 ttttggggat cttatcgact tatgttttat ggcttgaacc atttgccgta gctttggttg
    44761 ctttttccag cagattcgtg ttgcgattat tccatatttc taaaccaggt ggcttgtttt
    44821 ttgcgatgct ttctgccatg ggaacgagca tgcagctgcc aatcgctcaa ttaccgatcg
    44881 tctcacttta tttttttatg ggtgtcgttt ttgccctgat tgcggcagtg attacaaaat
    44941 tactggattc acggcctgag cagacaattg aaaaagcaac tttaaaagaa agatttcacg
    45001 aagagccttt agtgatcatt gattctgttt tctacagcgc tgccttattt ctttccgttt
    45061 atgtcagtca cggcttgaat ctgcataatc cttattggtt gaccttgtca tgtgcatcga
    45121 ttttgctagc agaaaacttg gatgcgatga agcatcgaca agtccaatat ctgattggat
    45181 cgatgggtgg gttatgtgtg tcggcattct tgtcatttgt gccgtttacg cagttgcaga
    45241 ccatttttct gatcactttt ctatatggaa tcgcacaatt tctagttgct agaaattatg
    45301 cagttgctaa tatttttctt aatccgatgg cgttgatgct atctacactt attcgtggag
    45361 catacttgat ttctttgatc gaatatcgtt ttttagggat cgtcatagga agtttcatcg
    45421 gtttaggtgt tgcgtgggta atgacggttg gtttgcaaca ttatttaacg gttgttcgtc
    45481 aaaaattaga atagaaggac aaatatatgt gccaaaagag gttatgacaa gatttttgtc
    45541 acaacctcta attcaaggtg ttcaaaagcc agattctcag cattaagtca aattcacaca
    45601 aaaatgtgga aaggaacttt caaaaaaatt ttatatttat tctatcaaaa aattttatat
    45661 ttattctatc aaaaaatttt gtttatgatg gtaactgaat aaactttcct gagatggtca
    45721 atgctttcct tgaaagtctt acagatattc tttcttcata gaaagtttaa gttttatagt
    45781 tagtgtacaa taaaagtatg tttataccat atggtgtccg gataatcagt catttaaaca
    45841 atgaggttca aagatatgaa aaggggaaat ttgatgaaga aaataagcaa tgaaatccaa
    45901 attctggcag aaactttaac tcttcccaaa gtcgttatag agcaaatgat tgtacaagca
    45961 aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg aactaatgga tcctaataaa
    46021 gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt tgcagcatta
    46081 gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc attgaagatt
    46141 ccaagaacta tctatttggc aacaatgaat gcttttacta gatttattca tgaacatttc
    46201 caagtaacag gaagctatcg ctttgaccgt ggtttttgga tttggcatta cactagtggc
    46261 ttgatctttc ggattggtga attggagtac gaaatgacat attttccgaa agggtacacg
    46321 gatctaagat tagaaggaaa gcagtgcctt tctcttcata ttccttccga tgcagattta
    46381 tctcagaata agataagaga tagttacgaa agtgccattc gtttttttga actttatttt
    46441 cctgattacc attaccaagt gatgtacaca gatacttggt tactatcacc caatcttact
    46501 aaatggttga aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg attattatca
    46561 gttgatgaac aggacgatag tggagtccct tggatctttg gacgagtaga tgcccaaata
    46621 catgattatc cagaaagtac gagtttacag cgacaagcaa aagagcaatt gcttgcaggc
    46681 gagcacattg gctctggctt aggtattctt acttcataag tttagtactt cgaaatagtt
    46741 taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
    46801 cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc
    46861 aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt
    46921 tagtgttcta tcgaacacac agtacgttca ataggtaaac tagctataac aatagatatt
    46981 aaagttaacg gacaagaggg ccttttttag gtagctaaaa cgtaataatg aaaatttatt
    47041 tccagagata ggagtcaatc agctagtctg atcgactgtt ttaacaagtt gactttcatt
    47101 ttaacttttg ataccattta aaacacaaat cgtaattgtt tcgatttgtg ttttttagca
    47161 tgactacaat caaagaagaa agtgggtcgt ccatatggaa aaaacagata tctcaagtgc
    47221 ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga agatcatcaa
    47281 agatgtgaaa cggaatagtg ggaaaaggta agaagaagga aacttaatta aaaaaatagc
    47341 cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg tgtaaggttt ccgaaagaac
    47401 tgctgttgat tttccatttt taacatatga taaattggta gaatctttct tttcaaattg
    47461 ataccattcc ctaattccag ttatatagtt aactacagaa ccacaaagca cgtacgttta
    47521 taaaagtatt atctgtagtt atttttcaat tccctttcaa cctcttattt tgaccagtag
    47581 tattgatcac tttacctttt aacacctttg ttcgtttttg aaacattttt agtcaagaat
    47641 ggaaacgtaa ctacataatc aaaggttttg cgaaatattt catgaaatat ttcatgtaga
    47701 agcgagcaat acggttgcaa ataaccatta tcgtttaata agcagttacg aaagctccca
    47761 atatctctaa cgttcagctc actccatttc ttttcttcaa aaaaatcagt gattcgtatc
    47821 tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat atgcaaaaaa
    47881 ataaaaaagc agttactatt gctagaataa catcaaggaa taataagttt tggttttcag
    47941 ataatagtcg ataagttgtg tattggaatt ttagatacag taataaagta tttttcatga
    48001 aattttgtga gaatcactat tacaagtatc tttaataaaa ttaatggtta aggaggaact
    48061 taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg tgatactaga ctcaaagttg
    48121 caggaataag tttttcaatt tgtgattgga agataaaaaa tgaaaaagaa gggctttttt
    48181 ttatactttg ttgattgtag tgtttatttt ccctctgttt agccaagtaa cattttctat
    48241 gactcaacca gtttcaagtg aggaacatga taaccttttt cgtgctacag aagagtttaa
    48301 gaaatatcag gaaaatattg ttccggagac tccattagct agtgagccaa ttactgatat
    48361 tgatggaaac caaataggat ggtatataca gtacgaagtt atggtggtaa ataatgactc
    48421 aatagtaaaa aatacagtag gcttagagct aacaccgatt gaaaaggtga gttcattgtt
    48481 aacgtatatt tatactgatg aaagtgacga gactgagatc attttaacgg attactcaaa
    48541 aattgctact gataaaaagt atatattgtg gatgtagaca ctagtgaaat actttatgat
    48601 atagaaattg atgaaaattt actagatgta gcacaagaaa tcgatcatca aaagcaggaa
    48661 gctattcgat atgctggtag aaaagggaaa agaaaatatt tattacgtga atgtagcaaa
    48721 agttagagaa gatgaaaatg agtggaaaga attcaagagt cgctactcaa ttaactcgac
    48781 tccgacattt acagtttaca gagaaggatc gatagaaaaa actgtttttt ggactaaaga
    48841 aagtggaatg tctttagctg aagtagaaga gtttttggat tatgttagta tgcaacagta
    48901 agggagttct tattatgaaa aattttgaca catattatgt tattgttttt tcgatatctt
    48961 tgctgttaat attactaact ttaatgcagt ataaagagta tccagagtat tttattttaa
    49021 cttttgtata tttagtaagt agctacacac ttctatataa attcagaagt tcttctagag
    49081 tttctaaagt ttgtttctta attagcttat tgattctata atatttttga tttatatagg
    49141 aaattaaaaa tattatagaa tcaacactca gagaacgggt tggtttttaa tagatttaat
    49201 aagtactgat aatgaaattt ctcctggttg ggaaaacgaa gttggttacc ctgtagaaga
    49261 attttttcaa gattactttg cggagtatgc cgataggata atgagagatt acgtaacaga
    49321 taaaactcaa gaagtcatca atcaatccca gtcattaaat gaattatctg ataaggcgaa
    49381 agaagaagca gttgccatta tttcttcagg gattagtgac tatattgata tgagtggtga
    49441 aatcaattat ggcgataaag acaaaattgt acgcatgata aaagctttta tcaaaacttt
    49501 tgatgtgaag gcagatctta agtttaatga tacttaccta gtaggaaaat taattaatat
    49561 ccttgggaca gagaaagata cggaaacgtt tatttcctct ttgtctatgt tgtttacaga
    49621 taagcatttt tcaactcagc ttggtggaga ggaactagtg gaaatctttt aaccattacg
    49681 cccagcatta ataaaagtat atcaaaaaag tactcctgat gatttttaag attggtttga
    49741 gaaataatgt gaaaacacta tttttaatgt taattataga tagagatgaa cgcgtcatat
    49801 ggttaaaaga atgaaaaagt caaagataca ctgctatatt tcactaagga tatagcagtg
    49861 tatctttcat gtcgtttcac tggcagtttt ttataaaagg aggtgtgcat ttcagttgct
    49921 tttctttggt agttagttga atcgtttaag aattaacgga tgtggcagac aggtgctctg
    49981 tccaaaaacc agtaaaatct ttgatggttc catctttatt tagctgtgcc tgttcaaata
    50041 ctgttttgtt tttaccgaat ggatcaattg caataattgt tccgatcccc gcacgtttgg
    50101 cagcaagtaa tcctgagtaa gcatcttcga taacaagaca atcagccgga gctaagctca
    50161 gtttgtctgc cgctttaaga aaaatatccg gttgcggttt cccagggaaa gagccgtcgt
    50221 catagacaat cttgtcccag tcaaaccagc gggctaaatc gaaaatatca aaataaaaag
    50281 caacattctc tttgacagta gccgtggcaa tcgttaatgg aatctgttgg tcagtcagct
    50341 ggtcaagagt cgcttcaagc ccttttgtca actgaagctc gttttcattt tgcaagcaaa
    50401 gcatacgata atagctttct ttttcttctg acaatacggc gatctcagag gcggtcaaat
    50461 gctctgaaat gaaatgtttc aaaatctccg tattcgtccg accatgaata ttttttaaaa
    50521 tatcctcgtc tgataaacca tcttttgtat gatcatgtat catatgcagc caagcagctt
    50581 catgcagatg agagtccaaa aacattgttc cgttgaaatc aaatataatc cctttcatag
    50641 ttacgctcct atagtggtat tttcggttga atcagcaatt tgcagatcga catattgtgc
    50701 atagtgctct tgaacctccc gcgagatctg gcgatccgta atgagcagat cgaaatcatg
    50761 caaattataa aacacataaa aatcatctcg attgaatttt ttattatcaa cgagtagata
    50821 tttcttacgg gaattattta gagcgatctg ctgtgcttct ccttcttcgg tactgtaagt
    50881 agagatcgct tcgttgtgaa cgccatttga actgataaat gcttttgtaa actttagtct
    50941 tcttaaattg tcgttggtga tcggtccgac aaatgcgccg gtatttttcc ggaaatcacc
    51001 gccaatcagt agaatttctg gtccatctgc ttgagcaaga atatcaaaaa ctggataatt
    51061 atttgtaatg atccgaattt tcttgttcag taaatgcgtc gccaatagtt cgattgttgt
    51121 acctggtcct aagaaaatcg tttctccctc gtgaatcaag gaggctgctg tggcagcaat
    51181 ttcttttttt tcttgaatct gcagagtggc tttttcagtg tgagaaagtt cttgatctaa
    51241 agtgtaggaa agactttgag cccctccatg gacacgcagc agcttgcccg atttttctaa
    51301 ttcatctaaa tctctgcgaa cggtcatatc agaaacatct aattgattga tgatttcatt
    51361 aacggtaagg attccttttt tattgaccat ttctacgata gtaagcaatc tttctttttt
    51421 caacattgtc ttcacctcta atttaaggat aatctatcat ataaacggac aacagtcaat
    51481 ctaattcgaa caaaagtaaa catttagggt ggtttttatg tttgttacaa tagattttat
    51541 tgctgttttc tggtttttat gattatttgt gtttgttttt gttgacaaat gttttggatg
    51601 cgtttacaat gcaatcagtt agaaagagcg aaaactgatt atagatttga ggagagatgt
    51661 acatgcttaa attaccagaa gattttattt ttggcggagc cacagcagcc tatcaggttg
    51721 aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg ggatgacttt ttagaggaac
    51781 aagggcgatt cagtcccgat ccggcaagtg atttttatca tcaatatgca aaggacattg
    51841 aattgtgtga acgttttggt gtaaatggtc taagattatc cattgcttgg agccgcattt
    51901 ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc tttttatcat cgtgtgttcg
    51961 aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt gcatcatttt gataccccta
    52021 aacgtttgtt tgaccatgga gattttttga atcgagaaac aatagaagca tttgtttcct
    52081 atgccatttt ttgttttcat gaattcaaag aagtcaaggt gtggagtacc tttaatgaaa
    52141 tctatccagt tgcaaccaat caatatttgt taggtgtttt cccaccagga atcaaatatg
    52201 attttacaaa gatcgtcgcc tgtcttcata atatgatggt tgctcatgcc cgtgtagtga
    52261 actatttcaa agaaaacgaa cttccgggtg aaattggtgt agttcactca ttagagacga
    52321 aatatgcggc aacagacgcg ccggaagata agcatgctgc ctttttagac gatgcattgt
    52381 cgatccgttt cttattagat gctacctatt taggctatta ttcaactgaa accttgactg
    52441 ctcttgatga gatatgtgaa gcaaatcagg ccagctatca ttttcctgaa gaagatttcg
    52501 ttgaattgaa aaaagcatcc acgcgtaatg actacttagg gatcaatcac taccaatgcc
    52561 attttgtcaa agcttacgat ggagaaaatg caatccatca taacggtacg ggtgaaaaag
    52621 ggacctctgt ttataaagtg aagggaatcg gagaacgtat ttataaagaa ggaattcctc
    52681 gaactgattg ggactggctg atttatccag aaggtctata tgacttgttg ctgcgaatta
    52741 aaagcgatta cccacattac aacaaaatct atatcactga gaacgggatg gggtataaag
    52801 atcagtttga agatggcatt attatggatc agccgagaat cgactatttg agagtctatt
    52861 tggaatcctt aagcaaggcg ataacagccg gggtaaatgt gaaggggtat tttttgtggt
    52921 cgcttatgga tcttttctca tggacaaatg ggtataacaa aaggtatggc ttgttttatg
    52981 ttgattttga aacccagaag cgttacccaa aagaatcagc ttactggtac aagttggtca
    53041 gtgaaaccaa aacgattatt taataagtga taatggagga agaaaagatg aataaagagg
    53101 aattacaaat gcttggtttt gagatcgttg catattcagg cgacgctcgc agtacattat
    53161 tgaaattatt gaaagaagta agacaaggaa actttgaaca tgttgattcg gcgttgaaag
    53221 aagccgacga aaatttaacc cttgcacata attcgcaaac aaaaatttta gcggaagaag
    53281 catctgggaa agagatggag atgggattca tttttatcca tgggcaggat catttaatga
    53341 ccactttatt gctgagagat ctgattcaag actttattgt actgtacaga cagaatcaag
    53401 gataggagaa gaacgctatg gatggaatca ttaaacaaat cgaaaaaggg aaaccatttt
    53461 ttgaaaaaat ctcacgtaat agttatttag gagccgttcg tgacggattt ttaacagcga
    53521 tgccagctat tttattttca agcattttca ttttgattgc tgcggttcct gagatttttg
    53581 gttaccaatg gcctgaatct gtctccacat ggctatggaa agtctataat tattcgatgg
    53641 gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg cttggctgat tcgatgaatc
    53701 gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt gatgctggcc tctgtggtaa
    53761 gtttcctgtt gttaagcgtc tctccgattg aaggtggatt ttcaacggaa tatatgggga
    53821 caaagggact actggcttcc tttgtcgctg catttttaac agttaattta tataagtttt
    53881 gtgtgctgaa agatattacc attaaaatgc ctaaagaagt tcctggaacg atttcgcaaa
    53941 ccttccgaga tatttttcct ttctcttttt cagtatttgc ggccgtttta attgatttag
    54001 gcattcgaca aatcttccaa atctcatttg cagaagcaat cattacggtg ctgcagccgc
    54061 tatttacagc agctgacggg tacttaggaa tcgctattat ctggggagcg atggcgctgt
    54121 tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc ggcaattgcg gcaattatct
    54181 atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg tgaacaagct tctaaagtac
    54241 tgacggtggg tttagggaat tttgtaggaa ctatgggagg aactggggca acattggttg
    54301 ttccttttat cttcctactc tttgctaagt ctaagcagtt gaaggcagtt gggaaagctt
    54361 cctttattcc agtaagtttc gctgtcaacg aaccattgct atttgcggca cccatgattt
    54421 tgaaccctta tttttttatt ccatttttgt taacacctgt tgtaaacgtt tgcctgttca
    54481 agttttttgt cgatgtattg ggcatgaaca gctttatgta cgttttgcct tgggcaactc
    54541 cagcaccgat cggtttggtt ctaggaacgg gcatgggtat cttagctttt gttctagcag
    54601 cggttctaat cgtcgttgac ttcctgatct atctaccatt ttgcaaagca tacgatgctg
    54661 tcttagtaga gaaagaagca caaaaagcag aggtgatcgc aaccgaggaa ggtgcttctg
    54721 ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt tatcagcgat gcaaataaag
    54781 aaatcaatgt gttggtactt tgtgctggcg cagggacaag tgcgatgtta gctaatgctt
    54841 taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc aatggcgggt gcttatggtt
    54901 ctcattacga aatgctgcag gattttgata tggtggtctt agcaccgcaa gtcaattctt
    54961 actatgatga tatcaaagaa gacaccgatc gcttaggaat caagctggtt gcgacaaaag
    55021 gagcagaata tatcggatta acgagagatc ctgaaaaagc tgttcagttt attctgaacc
    55081 aatttcaata aaggaggagc cataatgaaa atgggaattt ggttgcgtaa agctgtttta
    55141 tttgcagctg tgttaggggc tttgggggct gtttcaaaaa ctgttgaagc atctgccagc
    55201 gaatttattc gcggagcaga tatttcgatc ctgtcagata tggaaaaatc tggtgcaaaa
    55261 tattatgaag acgatatttc aaaagatgcc ttagagattt taaaaaataa tggtgtcaac
    55321 tatgttcgac tgcgtttgtg gcaggatcct tataatagta atggagaaag ttatggagca
    55381 gggacaaatg atctggaaac gacgattgac cttgcaaaac gagcaaaaaa tctgggactt
    55441 aaggtgctgc tggattttca ctacagtgat ttttgggttg atcctgggaa acagaatctt
    55501 cctaaagcat ggcaaggtct gacctttgaa gaaatgaata cggcattgta cgactataca
    55561 aagaacgttc tgtcggaaat gaagcagctg gacgtttatc ctgatatggt tcagatcggc
    55621 aatgaactga atagcggaat gctctggcct tatggcaagt cttggggaga aggcggggga
    55681 gaatttgatc gattggctgc ttttttgaag tctggtatcc aagctgttcg agacactcaa
    55741 cctaaaacaa ctccagtaat gctccactta gctgatggtg gcgatacagg agcatttact
    55801 tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg atttaattgg agtgtcgtat
    55861 tatccgtatt ggcacggttc aatgaatgaa cttcaaacca atatgaatgc gatcagccaa
    55921 cggtatggta aagaagtgat cgtagttgaa acagcttatg ggcatacaac agcgaatgcc
    55981 gatactatgc caaatgcttt tggtgaagcc gaagcagctg cggggggata tgaaccaaca
    56041 ccgacaggac aagcagagta tttgctggat cttgccgatc ggattcaggc agtaccgaat
    56101 aatcgcgggg cgggcttctt ctattgggaa cctctttggt acaacggaaa tgtgagttgg
    56161 gcaacacaag caggtatgaa ttatctcagt gttcaatcca ctatgggaaa cgaatgggac
    56221 aaccaagcga tgtttgattt tgctggaaac gccttgccaa gcttgcgtgc gtttaaacaa
    56281 gcaggggcgc aaataaatct agttaaaaat gcaagtttcg aaagcgatgg accaacgacc
    56341 agtccttcca attggcaaac ctggtttcaa caaggaaccg ctaagggtac gatcaaaacg
    56401 gaagcgggca ctttttttgg ggactacaaa ctaacttttt ggcaggatca agcatacgag
    56461 gcatcagctt atcaaaatgt tagtggcata agcaaaggaa cttacacatt gagtgcctat
    56521 gtaatgtctg ggggagagtt tgatactaat cagttatata tcaaaaatta tggtggagcg
    56581 gaactaaata ctgcggttgt taaaacaagt gaatggacaa aaattacaat caaagacatt
    56641 ccaattacaa caggtgtttg tgaaattggg gtttatagca aggcttcagg aaatgcttgg
    56701 acgaacgttg attttgtttc attggtgaaa caatagactg cggatcgttt cgattcaaga
    56761 tcggaggttc ccttcagcca catcgttagc gtagaaggca ggaatcgaac ctgcacctcg
    56821 cctttgccaa aaataaccag aaacgatttc cagtcatttt taccaaaacg agtaaagcac
    56881 cagacttcat ctacactttg tattatgcta aagagagttc aacgatttcg taagaagcaa
    56941 tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt gtttaagaaa gggtaacctt
    57001 agaattccgt cgtgaatatg atttgagcac ttagatggat agaaaaaagt tctcggaaaa
    57061 cagttcgttt ttcgagaact tctttttatg ataagaatga aacaaattaa cttatattat
    57121 agtctctttt ggtagggaac catcttattt ttaatgaaaa tcaagcattt tagctattga
    57181 agaatgttga tttataggga ttccccctcc atattatgtt ggctctttat tcccactctg
    57241 ttttcaacgt aaagtgtata aaacagaatg cgatactatc aagggagtta aaacaatata
    57301 cagaacagta aaacactata aataaaaata aaagtgcaat aaaagtgcaa tttttgcacc
    57361 taatcatact ctgtttatat atgaaaacta gattctgaat ccaatatttg gttaacgaga
    57421 ggcgttcgaa tttgaacgtc ttttatatat tactttcaaa taaatatgag gtagaatact
    57481 atctattttc tttttaaccc aattgttata atggagagtg taaaatattt tgtgtaaata
    57541 gaaaaaagga agtcccttct gtagaataga gttaccacaa cacattcaca gaagagagga
    57601 cttccctatg aacgatttta ctacagaaat tctaaagact ctagcgaaca aaggcgattt
    57661 gaatgaatta ttccgtgtcc atttggagaa agcagtcaat acgcttctca aaacggagtt
    57721 aacggctttc ctagattacg aaaagtatga tcgcattggt tttaacacgg gtaattctcg
    57781 taacggctcc tatgaccgta cggtcaagac cgagtatggg gaacttcatc tccagattcc
    57841 gcgcgaccgc aatggtgagt tcaagcaaca gactgttcct gcttatagac ggacgaatga
    57901 cacgttagag gagaccgtca ttcacctctt ccgaaaaggt attaccatgt cggaaatcgc
    57961 agacttgatt gagaaaatgt atgggcatta ctacacgccc caaaccatgt ccaatataac
    58021 aaaatcattt acagaagagg taacggcgtt taatgggcgg gagcttcatg accgttatgc
    58081 tgctatttat atggacgcaa cgtatattcc gttaaagcgg aaaaccgtcg ccaaggaagc
    58141 tattcatatc gcagttggca ttcgcccgga cggatcaaag gaagtattga gctatgcgat
    58201 tgcaccgact gaatccatca cgatttggga ggaaatttta ttggaccttc aagagcgcgg
    58261 tttgaaaaat gtcctcctgt tcatcacgga tggcttaaag gggatggtag gagcgattag
    58321 tcggttctat cccaaagctc gttttcaaca ttgttgtgta cacgtttccc gtaatatcag
    58381 tcataaagtg cgtgtcgatg atcgtaagga agtctgtgat gattttaaaa tggtgtatca
    58441 agcctcatct aaagaggtgg cgttggaagc acgtggtact tttgcggaaa aatggaaaac
    58501 cagctatcca aaagtggttg aatcgattct ttcgaacgat cacttgctca ctttctatga
    58561 tttccccttg gccatacgca agagtattta ttctacgaac ttgattgaat cctttaataa
    58621 acaaatcaag aaatacagcc accgcaagga acagttccaa aatgaagagt cgatggaacg
    58681 tttcttagtc tcgtcttttg atacttacaa ccaaaaattc ctaggtcgca gtcataaagg
    58741 tttccaacag gccgaaggcg agctcgaaca aatgctaagc caactgattg agaattagaa
    58801 acaatctgca gtagggaaga atcatttaca caaaattatt gacgctccct tataatgaga
    58861 acttttacta acataattta tgataaactt actatataat catattaatt aaatagttag
    58921 gagatctgct tatgtttata tctactcttc aaattcgaaa ttttagaaat tatgaatccg
    58981 aaatctttcg attcgataat gagacaaata ctattatagg tgagaatgat tcagggaaaa
    59041 ccaatgctct tactgcattg agaatcttat tagatgatag ttattactat agtagtaaaa
    59101 cactaaaaga atcagatttt tttcatggaa ttcaaaatgg gtggcaaggg cattggatta
    59161 ttatctctgc gacatttgaa ggaatcagcg aagaagaatt tgacaatgag atttgtgctt
    59221 ccatttcttt aaattctgaa agtcaaacaa tcttagaaga attgatttca aatgcagata
    59281 aaggtgtagg tagtatttct ctatttatta gacctaacaa agctattaga aagcaattat
    59341 ttgatatttc cactgaatta gactctcatc aatttaacga atttagaaat tctattcgtc
    59401 tatccgacta tgaattttac tacacatcta aatcaaatct aaatttctgt atcaatgaaa
    59461 attatgataa attggtagga agactcaatg acaatatagc tagtaatcct gaagaagacg
    59521 atgaagctct gttgggctca agaattgaca tgtcagatat tttcaagcat atttcggttg
    59581 tttatgttga cgctcttcga gatgttctta gagaaatgaa aaacaatcga aacccagtca
    59641 aaagaatcat ggaaacaatt gaatcaaaaa tatcatcaga taatgttgag tcattaaaaa
    59701 caattataca gcaattaaat gagactatta ccagtgttcc tgaaattagg aaaattggcg
    59761 aaaatattaa tcggcaacta aatagcataa ttggttcagt gtattctcct aatcttcttc
    59821 tttcctcaac tatgtcagat gatatgggtt ctttagcaaa atttctttca atgaagccag
    59881 aacaaaatat cgacttagac ttactagggt taggacatct aaatatgatt tatttagctt
    59941 tgaaaatagt cgaatttgaa gcgtgtcgtt caagagaact acttaatatt atgttgattg
    60001 aagaaccaga agctcatatt catcatcata ttcaaaaaac tctgttcgaa ggattaaatc
    60061 ttcaaaaaaa ctatactcag attctcatga ccacacattc tgtacattta gctgaagtgt
    60121 ctgaaatatc tcggatgaat gtattaaaat cgtttaatgg caaatctatc gttatgaatc
    60181 cagcaaataa tctgaactca tttgctaaag aaaagttaaa aaagaacaat ctaaatctaa
    60241 taaacgcagt agagagatat ttagatgtta aaagaaatgg attgcttttt tctaaaggtg
    60301 ttatcttagt tgaaggagat gctgaagaaa tacttattcc tcaaatagta aaaaaattat
    60361 ttggtataaa cttagacgaa cttggaatag gtttgattaa tgttggtagt acttcgtttg
    60421 aatatatcgc tagcttgttt gacgatgata gaatacagag aaagtgtgct attgtaactg
    60481 atttagatga acaggcaatc ccatcagaac atcgattgta taaaagcact gcacaagaga
    60541 aaggtcaagc aagaaaagaa aaattatcct ccctttttaa tgaaaacaat tgggttaatt
    60601 gtttttatgc taatacaaca tttgaaattg agtttttaga tgtgaataaa gaaaatattc
    60661 taacttatgt cagtccaatt atagatgacg cattcaaaga taaaaaaaca ataactgctt
    60721 ataaagaaga aatacaaagt gaacaatatt tagaaagaaa tttagcgatg ttaaaactag
    60781 ccaatcatgt tggtaagggg tggtttgcaa ttgagttagg tgaaaaaatt gactttttaa
    60841 tcaaaattcc taagtatatt cttaatgcta ttgcttttgc atgtcaggaa atagtagatc
    60901 tctcaattta taaaaaaatt ctactccata caatcgactt gtacgaggaa actacagaat
    60961 tgtcagcttt atcagctagt ttaaaaacaa gtgatacagc tgatttgaat atagcaataa
    61021 tttctttatt agagtacttt ggtaaagatg aggatgttgt gtatctaatc aatcagatag
    61081 aaaattacac aaaaatactt tatgctgagg tttcaaaatg acaaatatct tcgaaaaaat
    61141 cgtaaatgat ttaaatttag aacaaaaaga tgttgtggaa agtgaagata acctttatgt
    61201 aaatgcatgt cctgggagtg ggaaaacaag ggtacttaca aggaaaattg cttaccaagc
    61261 aattaaacac gatggatcac taaaaagaat aattgctatc acatacacta atagagctgc
    61321 tgaagaaatt aaggaacgcc taagtttact tagtatagat gatgatatta atatttgggt
    61381 ggggacaata catcagtttt gtcttgaatt tattatttat ccttttaaaa tgaatctctc
    61441 aagagtatca aaaggattta caattattga tgattatact caaagagctt acgtcagcca
    61501 aattaataat atgctgaatt taaatctcaa aacgtatgaa ctgaacaaaa ttgatttgtc
    61561 actttctcat gattttaaaa ttaatgaagt tcagtatact caagtttctg aaatgtatca
    61621 cactatgttg gaaaaaaata aagaaattga ttttgatatg attttactag tagcgtataa
    61681 aattttaact gtaaacagta acgttgcacg taatattgct agtaatataa gggcgattta
    61741 tgtggatgaa tttcaagata ctagagaatt acaatacaat gtaatagcta aattacttca
    61801 aaacaaccct caaattcagt caatgtttgt tggagatatt gaccaagcaa tttatggatc
    61861 attagatggt atagctaaat cagttgaaga actagaaatg ctaactagtc acacttttca
    61921 atcaaagacg ctacatggct gttacaggtc taatcagaga ttagtagact tctactctaa
    61981 ttttcagagt tgtccttacg agattgaaag cagagggaat aataaaaacg accgtggttt
    62041 tataagttat gattgcaaag ttactaagga ggatttaccc aacataataa aaaatataat
    62101 aaaggaaaag attgaaagcg gcattcatga aaaagatatt tgtgtacttg ctcctcaaca
    62161 ctatcctctg ttttcactgg gtgagtattt aaagaaagaa ttaccgtatt gcaattttga
    62221 tgctataaat atatcaccaa ttaaggtaaa taatcatagt ttatttttca agttagcaat
    62281 tttgtacttt actgaatcag gtgaaaaggt tcgaagaaga aagctaattg caaacgatat
    62341 tttaattata ttaaaaaatg aatttggaat agaagttaaa gattatttta ttgacttaga
    62401 tttattacag ctaataaaca gtgtgaaaag aatgtatagt ggagacgaca acggtgttga
    62461 tttatacaaa tttgttacca aacatatatt tgttaatctt aatattgacg agaaaaatta
    62521 cccgtctatt tttaagcact atctattttt tattaacgaa gtagaagatc ggataaaaaa
    62581 taattcatta tctagtagtg tatctagttt taagaagatg tttaaatctc gagatggtat
    62641 cacacttact acagcacata aagttaaagg aaatgagtat gatactgtta tcgctattaa
    62701 tcttctaaac gggaaaattc ctcattggaa tgaaattttt aatgtttctg ataaaggaat
    62761 tagttcagcg agaaaactac tatacgtaat ttgttcaaga gcaaaaaata atttatttct
    62821 tttctcagag gtgggttatt ttacgagtaa aggagacttg ctttatccca ctcaattatt
    62881 agataaaata gaatttgatt ataatattta aaatacctag gtagtcgttg ttttaaatat
    62941 agtaggaatc ggacgctcag tacggagcgt ctattttttt acccaatttt gaaaggaagt
    63001 gaacttatga aaataaaaaa tcaagaatca aaaggtcgct ctcccccctt taaaaccatc
    63061 acacaaataa gattcattca aacataaaaa cagaaaggat aggtaaaaat atggaactta
    63121 aatatgtcat tcccaatatg gaaaaaacat ttggacaatt agaatatgct ggtgaaggga
    63181 acattgaaca acgtcgaata aatggcagac caaccattct ctctcgtagt tacaatttat
    63241 actcaacgat tcaacgagca gatgatattg ttgtcattct tccctccgaa gctggcgaga
    63301 aacattttga atccgacgaa aaagtcaaac tcatcaaccc acatattacc gcagaaggtt
    63361 ataaaattgg caatcgagga tttaccaatt acattatgca cgcagacgat atggtgaaag
    63421 cataagaaag gaaaggtgaa aaaatatgag attagcagaa ggtattgtga ttgaaaaaga
    63481 ccagacattt ggcacattga aattttccgc cttgcgtcgt gaggttcgta tccagaatga
    63541 agatggtacg gtttccgaag aaattaaaga acgtacctat gacttaaaat caaaaggaca
    63601 aggacgcatg atacaagtca gtatccccgc ttctgttcct ttgaaagaat ttgactacaa
    63661 cgcagaagtg gaattaatca atcctgtggc agataccgta gcgacggcta cttttcgagg
    63721 ggcagacgtt gattggtacg tgaaagcaga cgatcttgta ttaaaaggac agacaaaacc
    63781 tcatcagaaa tataaaaaag aagcgtccga aagtgaaaaa taggtgttgc ttatgacaaa
    63841 cacaccattg attttgaaag aaattccgaa ggatgaagcc atttctttta ttcggcaata
    63901 ccattattca aagatactcc ctagattgtg taaatacttt ctagggattt tttcagaaga
    63961 aaaattatta ggcgttgtgg aattaggctg gggtacgcaa cccctacaaa ccatacgcaa
    64021 actctttccc gacagttccc ttcaaaccac agattattta gaaattggaa agatgtgttt
    64081 tcttccagaa atgaatcaaa ccaattattt tggcagtcaa gctctttcag ctctaattaa
    64141 gtggttgaaa gaacatacgg actgtcattt tttatataca ctggcagatg gaattgaggg
    64201 aaaatgtggc tatgtctatc aagcgtccaa cttcttttac tgcgggtatt tcaagacaag
    64261 tgtctatcgt gataagcagt catgggaaaa gatacaccct cgaagtgctc gccttttatt
    64321 agaggaaaat gctcgctttg aacaggtaga gaaaaagcat tggctttccc aggcattttg
    64381 cgaatacaaa gggattgaga aaatcaatgg acgcatgttt cgctatctct atccgttgac
    64441 aaaagaagcg aaaaaactgt taggacacac tctctatcga cgtcattatt atccgaaaga
    64501 aaaaaattta cgctttgaaa agcgaatcgc ttatcagaaa tatgaagcca tttctcaacc
    64561 aacttttgat aaacaggctc gtatctacaa tacacaatta ttttgatagg tggaaaggag
    64621 gatttttatg ccattgcttc atgacagagg agagcgaatc aaagccaacg ataagcactt
    64681 ggtctatcat tttgtactaa tttcattgct ggtagttttt ctagtcgtcc tactcccttt
    64741 tcattggaga gcgttacaat cggtgaactg gcaagcagtt cagttagata catttttcta
    64801 tcaacttcat acgccatact tttggagcag tattctcact gctctttttg tatgcggact
    64861 tatcagctgg ctttattatc actatcgtat agattctata aaacagttag agcaccgtca
    64921 aaagttagct cgtatgattt tagaaaatca ttggtatgaa gccgaagaaa ctcaatcaga
    64981 gggattcttt aaagatttac ccagcaagaa aaccaaacaa cgaatccgcc attttcctaa
    65041 aatatattat cgaatgaaag atggactaat ccatattcat gtagaaatca ccttagggaa
    65101 atatcaagat cagcttttgc acctagaaaa caaactagaa acaggattgt attgtgaatt
    65161 agtggaaaaa acgttgaaag attcttatgt agagtatgtc ctactttatg atactattgg
    65221 caatcgaatt ggcattgaag acgtggtagc tcaagatgga cgtgtcaaat tgatggaatc
    65281 ggtctattgg gagttcgatt ctctccctca catgttaatt gctgggggca ctggtagtgg
    65341 aaaatcctat tttattctca cattgattga atctctcctg catacaaatg caaagcttta
    65401 tattcttgac cctaaaaatg ctgatttggc agacttaggg gcggtcatga ataatgtcta
    65461 ttaccgtaaa gaagatatgt tggcatgtat caatcaattt tacgaagata tgattgatcg
    65521 cagtgaaacc atgaaacaac accctaacta taaaacagga gaaaattatg cttatcttgg
    65581 tttgtctgcc aattttctta tttttgatga atatgtggca atgatggata tgctaggtcg
    65641 tgaaagtacc accgttattc ataaactcaa acaaattgta atgttaggac gacaagcagg
    65701 cttcttttta attcttgcct gtcaacgtcc agacgcaaaa tattttagtg atgggattcg
    65761 ggacaacttt aacttccgtg tggctttggg tcgtatgtct gaaatgggct ttggtatgat
    65821 gttcggaagc gatacacaaa aacaattttt cttaaaaccc atcaagggaa gaggttacgt
    65881 ggatacagga aaaagtgtga ttagtgagtt ttatacaccc cttgtaccaa aaaggtacga
    65941 tttcttagga gaaataggaa aagtcattca aaaaaagcaa tctgagcctg taccgcacga
    66001 agtgaaaggt acaggttcag acttgctttg attggtgtgg cgttagccac gccaatcctt
    66061 tagccccctc tatctaacag gggggcacaa atacaactga aaacaggcaa ttctcatcaa
    66121 ccaatgttga tggtacaaag gattgcggaa aatatgaaag gtgtaaactc aagggtcata
    66181 gtttacatct tttttagatt ggaggtttgc gaatggaaaa cgaaaaaatt tggattaagg
    66241 aattgaaaga aaagcgactg gcttatggcg tttctcaaaa taaactggcg gttgcttctc
    66301 atattaccag accttaccta tcggatattg aaacaggcaa ggcagtccct actcaacagg
    66361 tgaaagaaga tttactgaac gctttggaac gcttcaatcc cgataaccca ttggagatgt
    66421 tattcgacta tgtacggatt cgattcccta ccaatgatgt ggctcaaatt atcggtgagg
    66481 ttttacgttt gaatatggat tatatgctac acgaagactt tggctattat tcttatcccg
    66541 aacactatcg tttcggtgat attgttgtcc tagtctctca tgatgtaagt aaaggtgttt
    66601 tattagaact gaaaggaaaa ggctgtcggc aatttgaaaa ctttctattg gctcaacatc
    66661 ggagctggta tgatttcttt caagattgca tggaacataa aggtattttc aaacgcttgg
    66721 atttagctat caacgataaa acagggattt tgaatattcc agatttggca aagaaatgta
    66781 aacaggaaga atgcatttcc gtctttcgaa gctttaaaaa ttatcgcagt ggtgaattgg
    66841 ttcaccgtga tgaaaaacca tacatgggaa acacacttta tattggctca ttaaaaagtg
    66901 aagtctattt ctgtatatat gagaaagatt atgagcaata cgtgaaaaat gatgttccct
    66961 tagaagacgc agaagtaaag aatcggtttg aaattcggtt aaaaaatgac cgagccaccc
    67021 aagccatgaa agatttattg gcacatcaac aggcggaaaa aacagccttt gaaattatca
    67081 atcgctatat ccgctttgca gataaagacg acactaaacg tcggagtgat tggaaaacta
    67141 atgaacgttg ggaatggttt atcggtaaaa atcgtggagc attacgccta accacacagc
    67201 cagagcctta ttcttttgaa cgaacattga actggttaca tcatcaagtc gcccctacat
    67261 taaaaatcgc aagcatttta gatgttctca acggtacaac cattatctcc accatgattc
    67321 aggaagccaa actgacagaa aaacatgaga aattaattga acaacaacat ctagccatgg
    67381 aggatttgat tacatgagcc ttttaacaaa agaattaaag aagttagggt ttcagtgtgg
    67441 cattgagttt caagcgtata tacaaaatac agggaaatat acgtctctca ttattgaggg
    67501 aaaacggcaa gctggtgata ccatctatac ctatgatttt tacaaggtga gattttataa
    67561 taattatacc aatcgagtaa ccgtctatgg agagcattta accccttttc aattattaag
    67621 gcgtgtaaaa agctatatct attatcgaga aaaatatctt aaggaaagga ggacaatcac
    67681 atgaattttg ggcagaattt gtacaactgg ttcttggata atgcacagtc attggtattg
    67741 ttagcgattg ttgtcattgg actgttttta ggttttaaac gagaattttc aaaactcatt
    67801 ggcttcttga ttattgctct aatcgccgtc ggacttgtgt tcaatgcagc tggcgtgaaa
    67861 gatgtgttat taaacttatt taaccgaatc attggtgctt aacagatatt tttcatgata
    67921 aaataggaag tatatatttt gttatgaaag gatttatgaa tatgtttaca aatgatcaat
    67981 ttaaatctct tttaattaaa acattagaaa gaaagagctc ttcaaattat tatgaaggag
    68041 gtaacgagat tgtttctaaa atgaaaatat cagaggtaac tttagatgag actgacgatt
    68101 ttacttatta taaaggatat aaaaagggct ggaatacgct ttgcacatat cttaaaataa
    68161 gagttccttt tgatgattta gacttttttg aaagtcataa agatttgatt acccagacag
    68221 caagctccat atatgataaa caaggtgata atgtattagt ggatactatt ttagtaccac
    68281 ttccagagaa ttacgaagta attaacttta gtcagttgaa aattagtgat gtggtttcac
    68341 aagctattga agacgctgag tcttttatga gtaatggtga atatcaacgt gcctttgaca
    68401 gagttcacac tgcttttcat ggatatttaa ttgaaatact aaaaaaatat gaaattacag
    68461 ttcctagaga cgaaaatcta tctaaattat atagtaggat acaacaatta attgaaaaag
    68521 aaattcaacc tactgaactt gctgatatag tgaagacaac gataaggtca tcaaatggaa
    68581 tgattagctc tcttaatgaa gcaagaaata ggcattcact tgcacaccct aatacaaata
    68641 ttattggaaa gagagaagca aaactaataa taggtatttc aagtacagtt acagattata
    68701 ttagcggata ccttgataag tagcgtcatt aactgattgc tacttttttt atgactattt
    68761 ttataaaaag gatgtgataa gaattggaaa tgaaagtcta tgtggcaaat ttaggacggt
    68821 ataatgaagg tgaattagtc ggagcatggt ttactccacc aattgatgag gaagaaatgg
    68881 cagaaagaat cggtttaaat gaggactacg aagaatatgc aatacatgat tttgagcttc
    68941 cttttgatgt ggacgaatac acgccgatta gtgaaatcaa ccgtctatgt gaagccattc
    69001 aagaaatcga aggtacacct atttataatg aactcaaaga aattcaaggc atgtggttta
    69061 gtagcttgga agaattactg gaaaacaaag aggatattca ttgttatagt gattgtgatt
    69121 cgatggaaga tgtcgcccgt tattacgtgg aagaaacagg acagcttggt gaagtccctt
    69181 ccaatttaca aaattatatt gactaccaat ctttgggacg tgatatggaa atagagggta
    69241 attacctagt tacctctcat ggggtatttg aatattgtca gtaagtttaa caatccgtgt
    69301 tataattaaa ttaataaata gcacggagag gtataaatta tggtaaatgt atttgaaaat
    69361 cttaaactat taaaactaga catgaaagat aaaggctggg tgatagattc cttttacttt
    69421 cgttacaaac agcaaaatta tattgtactt gttaagctat ttgaaaaaga ggaaaaagtt
    69481 ccagaatatg ctctgttaaa actagaattt ttaaaggaaa acgatttttc agatatgcta
    69541 gctgtctatg ctaattcggt aaaattatat acagacacga aaacaataag agaatatttt
    69601 ggtatcgaat acagtagtaa cttgggagat gttttatttc aatttagcca aactcttgct
    69661 cgatttattc cgacagaagt tagtgagaag aaaaatgaag accaaaaaga agccatgtgt
    69721 ttctcattaa gtcaaagtga ttcagaagat cccagaaaaa aatattgttt ttcagttaga
    69781 agaaatcctt taaagggaaa tggtgagctg ggaaaacgaa gtccttttaa tgacaataaa
    69841 acgagattgt atagacccag cttatatgaa cgattagggt cagataccaa tttaagtttc
    69901 agatattcaa tgaatccaga tgatgaagaa actgatgaag gtattattgc aaaatggaca
    69961 aaaaataaaa ttgaatagtt aaagcattga aagagcaatc acctattttg attgttcttt
    70021 ttctattttt acggaaagga cgtgaagaca tgaaaaaaat aagaagttac accagtattt
    70081 ggtcagtaga aaaagtgatt tatgcgatta atgatttaca actccctttc ccaattacct
    70141 ttacgcaaat gacatggttt atcgtttctt tgtttgtcgt catactcttt ggcagtttac
    70201 caccactttc tctgattgac ggagcactac tcaaatactt agggattccc attgttctca
    70261 ctgggttcat gtgccaaaag acctttgacg gaaagaaacc ctatggattt ctaaagtcta
    70321 tcattaccta tgctctacgc cctaaagtaa cctacgctgg caaacaaata cgattaaaaa
    70381 aagaaacaat gaatgaatcg attacgattg taaggagtga acaactagat ggcatatccg
    70441 attaaatata tggaagataa tctcgtattt aatcatgatg gcgaagtatt cgcttattat
    70501 gaattaattc cctataatta cagtttttta agttccgatg aaaaaattca agttcatgat
    70561 aatttctgtc aattgattgc ccaaaatcgt gatggcaaga ttcatgctct gcaactagca
    70621 accgaatcaa gtattcgagc cacacaggaa caatcgaaaa aagaaatcac tggacgatta
    70681 aaagagatag cttacgaaaa aatagatgaa cagaccgaag cgttaatttc tatgattggt
    70741 gacaatcaag tagactatcg cttttttatt ggttttaaac tctacctcaa tgaacaggaa
    70801 gtatccgtaa aaaatgttgg gaaagaaatt caaaaagcat ttgcggaatt ctttcatggt
    70861 gtgaatcaca aattaatggg cgattttgtt tctatgccta tggcggaaat cgaacgcttt
    70921 tctaagatgg aacagttgtt agaaagtaaa ttatccagac gctttcagat tcgtaaattg
    70981 gagaaagatg attttggtta tattattgaa catctttacg ggcaaacagg tgtccctttt
    71041 gatgactacg actaccattt accgaaacga tacgaagata aaaaagtgtt ggtaaagaaa
    71101 tacgatattc tcaaacccac tcgctgttta atcgaagaaa atcaacgcta tttacggatt
    71161 gaacaggaag ataccactac ttatgtggcg tattttacaa ttaatagtat tgttggtgaa
    71221 ttggatttcc ctaatagtga aattttttat taccagcaac agcagtttac tttccccgtt
    71281 gataccagta tgaatgttga aattgtcgcc aataaaaaag ccttatctac cgttcgcaat
    71341 aaaaagaaag aactgaaaga tttagatagc cacgcatggg aaagcgacaa cgaaaccagt
    71401 actaatgtgg tggacgcttt agaatctgtc gatgaattag aaagtaattt agaccaaacc
    71461 aaagaatcta tgtacaaact aagctatgtg gtacgggtat cagcaaagaa tttggacgag
    71521 ctgaaacaac gttgtgatga agtaaaagat ttttatgatg atctgtctat caaattagta
    71581 cgaccttttg gcgatatgct aggcttgcat aatgaattta ttccctcaag caagcgatat
    71641 atcaatgact atattcaata tgtcacgtcg gattttttgg ctggtcttgg tttcggtgct
    71701 acacaaatga ttggtgaaaa ttctggtatt tacgtcggtt acaatctcga tacaggcaga
    71761 aatatttatc tccaacctag ccttgcaagt caaggaatta aaggctctgt aacaaatgca
    71821 ttagcgtccg cttttattgg ttcattaggt ggcggaaaat cattctctaa caatatgctg
    71881 gtctattatt cagtactctt tggcggacag gcaaccattg ttgacccaaa agctgaacgt
    71941 ggtgaatgga aagaaacctt acctgatatt gcccatgaaa tcaatattgt taatctcacg
    72001 agtgagaacg acaataaagg gttacttgac ccttatgtga ttttaaaact cccgaaagat
    72061 tcagaaagcc ttgccattga tattctcacg ttcttaacag gtatttccag ccgagatagc
    72121 gagaagtttc ctgtcctgcg taaagctatt cggagtgtaa ctcaaagcaa acaacgaggg
    72181 ttgttattgg tgattgatga attgcgaaaa gaagatacgc ccatcagcaa tagtattgct
    72241 gaccatatcg aaagctttgt cgattatgat tttgcccatc tgttattcag tgatggcagt
    72301 gtcacccaat ccattagctt ggaaaaacaa ctcaatatta ttcaagtggc agatttggtc
    72361 ttacccgatt ccaatagctc ttttgaagaa tacactacca tggaattatt aagtgtggca
    72421 atgctgattg tcattagtac ctttgcttta gactttatcc actctgaccg ttccattttt
    72481 aaaattgttg accttgatga ggcttggagt tttttacaag tggcacaagg aaaagctcta
    72541 tctatgcgat tggttcgagc aggacgtgcc atgaatgcag gggtctattt cgttactcaa
    72601 aacgcggacg atttactaga tgaaaagatg aagaataata ttggcttgaa atttgccttt
    72661 cgttccactg acctagtgga aatcaaaaag accttagaat tttttggtgt ggacaaggaa
    72721 gatgaaaaca atcagaaacg cttacgtgaa ttagaaaatg gacaatgttt agtttcagac
    72781 atctatggtc gtgtaggggt tatgcagttt cacccgattt ttgaagagtt gcttcatgcc
    72841 tttgatacca gaccgcctgt gcgaaatgag gtggaagaat gacacaaaaa caaaagaaat
    72901 ttcttcacta tagttggata acgctccttt gtgtgggcgt tattttactt ttattaggca
    72961 cgctgggcaa tgcagtacaa gcgacaggct tagttgatga aaccattgat acaagcaatg
    73021 aatactccaa gtatggtttg aatcaatatc agcttgatta ttatgtggac aatagctggg
    73081 gctggcttcc atggaattgg agtgatggca taggacaatc ggtgatgtat ggattgtatg
    73141 ccattactaa ttttatttgg acaatttctc tttatctatc gaacgccaca ggttatttgg
    73201 tgaaagaagc ctatgcctta gatttcatta gtcaaacatc ccaagcaatt ggcgaaaaca
    73261 tgcagacgat tgcaggcatt acaccgaatg gcttttccag ttcagggttt tatgtcggtt
    73321 tcctccttct ttttattctc attgttggaa tctatgttgc ctatacagga ttggttaagc
    73381 gagaaacgac gaaagtgata cgagctgttt taaactttgt cgtggtgttt attctatcgg
    73441 cttcctttat tgcgtatgca cccgattata ttgcgaaaat caatgatttt tccaaagatg
    73501 tcagtaccgc cagtctgaat attgggacaa aaattgttct tcctaacacg gatagtcaag
    73561 ggaaagacag tgtggacatg atacgtgaca gcttattctc tgttcaagta aagcaaccat
    73621 ggctattgct tcaatatggc tccactgatg tagaagcgtt aggggaagaa cgtgtggaaa
    73681 gtttattgtc taccagtcca gatacaaaca atggtgaaga tagagaaaat gtagtgattg
    73741 aagaaattga agatcatgac aatacctatt taaccctacc gaagacgatt tccagattag
    73801 gaacagtctt ctttttgttt gtattcaata ttggtatctc gatttttgtt ttccttctaa
    73861 caggaatcat gattttttcg caagtgctat ttattatttt cgctatgttt ttgccaatca
    73921 gtttcctatt aagtatgttg ccgagttttg atggcatggg caggcatgcc attaccaagt
    73981 tatttaatgt gattatgaca agggctggta ttaccttgat tattaccgtt gcctttagta
    74041 tttccactat gctttattcg ctgtcagcaa gttctccctt tttcatgatt atgtttttac
    74101 aaattgtgac ctttgcaggg atttatttta aactgggcga tttaatgagc ctattcactt
    74161 tacaaagcaa cgactctcaa aacatgggca gacaagtgtt tcgcagacct cgtcaaatga
    74221 tgaatcgaca aaccagaaga tttcaacgca gtatgagtaa gatttttcgt ggaaaagcag
    74281 ggtcaacgaa gcaaaagaca atgacaacaa agcagaatca aaccaataaa gctaaccata
    74341 ctcgtcaaaa tgaacggact acaccaaaga aagaaacagc actttccaat gtgaaaaagc
    74401 aacaaggcgg tatcgggcaa cgattaggtg aaaagacagc ccatgtattg gacacgaaaa
    74461 atcgtctagt caataaaaga aagcaggcaa aacaacagat acaggcgaca ccaacccatg
    74521 tcaaatatgc ccttcatcaa ggaaaagaga atgtcactca taatgtaaca gactttaaac
    74581 aatctatggc agataccaaa gctcaacgca aacaacagcg tatgaaccag caggagcaaa
    74641 aacgaaagaa cattgctcaa aagcgtttgg agctggataa agcaaaagaa aaaagacgaa
    74701 aagaaaaccc atcatctcct gttcagaata accagcagca tgttcgcaag cgtcagcaaa
    74761 ccgtcacgcc tgttttgtca caaaacacta aacgtgaaaa tcatcagcga ccattgaaaa
    74821 aagagcaaaa acaaaagaca ccaccgaagc aattcaatca gaggaagcta aataaaagaa
    74881 cggataagcg aggacaacaa acatgaagct aaaaataaca gtgatttgta gtgtggtctt
    74941 ctctctcttc ttttttctct tattattcct agtcattttc tttgcagatg atacggacag
    75001 tggcgaaaac aacaaggatt cttctattcc acaaggcggt gtgaccgttt caccagaagt
    75061 gttggcacac cgtccgttga ttgaaaaata tggtaaggaa tatgggattg aagactatgt
    75121 ttcttatatc ttagccatta tgcaagtgga atcgggcggt acagcagaag atgttatgca
    75181 aagttccgaa tctttgggtt taccgcccaa cagtttgagt accgaagagt ccatcaaaca
    75241 aggggttaaa tatttcagtg aattattaac cagtgcagaa caacaaggag tggatataga
    75301 ttctgttatc caatcttata attatggcgg tggcttttta aattatgtga ggagtcatgg
    75361 gaaaaaatat acctatgaat tagccgaaca gttttctaaa gagaagtcgg gtggtcaaaa
    75421 agcagactat cccaatccta tagccatacc tgtgaatggt ggttggcgat ataactatgg
    75481 aaatcagttt tatgttcagt tggtttcaca atacctaacc gacacttccc caacagaatt
    75541 tgatggtgaa accgtgcaag tcattatgga cgaagccttg aaatacgaag ggtttcccta
    75601 tgtctttgga ggggcgtcgc ctaccacctc ttttgattgt agtggcttaa tacaatgggt
    75661 gtatgacaaa gctggcattt ctctccctcg tgtcgcccaa gatcagtatg acgctacgca
    75721 agaaatctct atggaagaag cccaagcagg cgaccttatc ttctttcatt caacctataa
    75781 tgcaggcaca tatgtgactc atgtggcgat atatttagag ggaaatcgct tttatcatgc
    75841 aggcgaccca atcggttatg gcgacttaag cagtcgttat tggcaagacc atctgattgg
    75901 ggctagacgt gttattcata actaagaaag gaatgaatca aatgattata aaaatcgagc
    75961 gaaaagaaaa gaaggagaaa ccaaagaaat ctaaaaaacc gagcaagcaa agaaaagttc
    76021 cgatgattaa agttggcacg cataagaaat taacctttgt tttatgggtt ttattgattg
    76081 gtagtgtcgg atttggaatc tataaaaatt ttactgccat tgacactcat actgtccgtg
    76141 aaacagaaat cattaaacag cagattgtcg ataccaacca agtagaaagt tttgtgaaat
    76201 cctttgcgaa agactacttt tcgtggcaac aatcccaaga agccattgat aaacgaaatg
    76261 aaaaattgac ccattatttg acggaagaat tgcaggtatt aaatgaagaa atgattcgta
    76321 aggatattcc tactagttct agtgtgaacg atatacaggt gtggcaggtt tctcaagtga
    76381 atgagaacac ctttgaggta ctgttttctg ttgaacaagt tattaccgaa gacaaagaca
    76441 aggaaactat atcgtctagc tttcatgtgg ttgtccatat agatgaatca gataatatgg
    76501 ttattatcaa aaatccgaca atgagtaaga aacctcaaaa atcggactac caacccaaac
    76561 agctagaaag tgaccataca gtagatacag aaacgatgga cgaaatcact agctttttag
    76621 aaacgttctt ccagctctat cctaccgcca cagaaaaaga attgacttac tatgtaagta
    76681 atcatgtgtt acctatgatt aacaaggaat atgttttcga ggaattggtg aatcctatct
    76741 ttaccagaaa agataaccaa gtaatcgtga atgtcgctgt gaaatattta gatcaagaaa
    76801 caaaggcaac ccaaatctcg caatttgagt tgatattaga aaaacaagat aattggaaga
    76861 ttgtaaaata acaaatattg gtacatgatt acagatactt tgtaatcatg tactcttttt
    76921 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtgacta
    76981 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
    77041 cgggaacaaa taattagatg tcctttttta ggagggctta gttttttgta cccagtttaa
    77101 gaataccttt atcatgtgat tctaaagtat ccagagaata tctgtatgct ttgtatacct
    77161 atggttatgc ataaaaatcc cagtgataaa agtatttatc actgggattt ttatgccctt
    77221 ttgggttttt gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat
    77281 gttgatgcag gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca
    77341 gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag
    77401 agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac
    77461 atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt
    77521 ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata
    77581 ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac
    77641 caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa
    77701 attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa
    77761 tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc
    77821 ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa gcataagatt tcagaattgt
    77881 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
    77941 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
    78001 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatat acgcctttat
    78061 agtggagtac tacatttacg agattcggtt agagtatcag aaaaagaaaa aataaaagtt
    78121 acagaaatgt atacttcaat aaatggtgaa ttatgtaaga ttgatagagc ttattctgga
    78181 gaaattgtta ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg agatacaaaa
    78241 ctattgccac agagaaaaaa gattgaaaat ccgcaccctc tactacaaac aactgttgaa
    78301 ccgagtaaac ctgaacagag agaaatgttg cttgatgccc ttttggaaat ctcagatagt
    78361 gatccgcttc tacgatatta cgtggattct acgacacatg aaattatact ttctttctta
    78421 gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca tgtggagata
    78481 gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc agaatatacc
    78541 attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc tgtatcaccg
    78601 cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata cttaaatcaa
    78661 tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg attatatggt
    78721 tggaatgtga cggattgtaa aatctgtttt aagtacggtt tatactatag ccctgttagt
    78781 actccagcag attttcggat gcttactcct attgtactgg agcaagcctt tagaaaagct
    78841 ggaacagaat tgttagagcc atatcttagt tttaaagttt atgcaccaca ggaatatctt
    78901 tcacgggcat ataacgatgc tcccaaatat tgtgcaaata tcgtaaatac tcaactgaaa
    78961 aataatgagg tcattattat tggagaaatt cctgctcgat gtattcaaga ttatcgcaat
    79021 gatttaactt tttttacaaa tgggcttagt gtttgtttag cagagctaaa aggatatcag
    79081 gttaccactg gcgaacctgt ttgccagacc cgtcgtctaa atagtcggat agataaagta
    79141 agatatatgt tcaataaaat aacttagtgc gttttatgtt gttatataaa tatggtttct
    79201 tattaaataa gatgaaatat tctttaatat agatttgaat taaagtggaa aggaggagat
    79261 tgttattata aactacaagt ggatattgtg tcctatttgt ggaaataaaa caagactacg
    79321 aatacgagtg gatactatac ttaaaaattt ccctttatac tgccccaaat gtaagaacga
    79381 aactttaatt aatgttcaaa aa
//
LOCUS       DASHWW010000007        73518 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.007, whole genome shotgun sequence.
ACCESSION   DASHWW010000007 DASHWW010000000
VERSION     DASHWW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.007"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            14..1141
                     /locus_tag="U2R64_000563"
     CDS             14..1141
                     /locus_tag="U2R64_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8917409.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1361..2503)
                     /locus_tag="U2R64_000564"
     CDS             complement(1361..2503)
                     /locus_tag="U2R64_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8917410.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGICLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2508..2693)
                     /locus_tag="U2R64_000565"
     CDS             complement(2508..2693)
                     /locus_tag="U2R64_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEM8917411.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3047..3292)
                     /locus_tag="U2R64_000566"
     CDS             complement(3047..3292)
                     /locus_tag="U2R64_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917412.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3286..3687)
                     /locus_tag="U2R64_000567"
     CDS             complement(3286..3687)
                     /locus_tag="U2R64_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8917413.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="U2R64_000568"
     CDS             complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="U2R64_000568"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEM8917414.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KLITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWKERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLQKRWSSIPNFSYKK"
     gene            complement(5703..7469)
                     /locus_tag="U2R64_000569"
     CDS             complement(5703..7469)
                     /locus_tag="U2R64_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEM8917415.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IISDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIEPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7482..8276)
                     /locus_tag="U2R64_000570"
     CDS             complement(7482..8276)
                     /locus_tag="U2R64_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEM8917416.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYYQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGEYVDIEQKFIDTFWKNLTNK"
     gene            complement(8286..9662)
                     /locus_tag="U2R64_000571"
     CDS             complement(8286..9662)
                     /locus_tag="U2R64_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8917417.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLIIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQFKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKTSNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANIQTGDVLEKLYNASTLIPSICFFIVGLILFFLYPLSKDKVLENC
                     ELLKQKYK"
     gene            complement(9782..10429)
                     /locus_tag="U2R64_000572"
     CDS             complement(9782..10429)
                     /locus_tag="U2R64_000572"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HEM8917418.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSLENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10522..11949)
                     /gene="uxaC"
                     /locus_tag="U2R64_000573"
     CDS             complement(10522..11949)
                     /gene="uxaC"
                     /locus_tag="U2R64_000573"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEM8917419.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLGYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(12023..13102)
                     /gene="uxuA"
                     /locus_tag="U2R64_000574"
     CDS             complement(12023..13102)
                     /gene="uxuA"
                     /locus_tag="U2R64_000574"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEM8917420.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLQTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13105..14736)
                     /locus_tag="U2R64_000575"
     CDS             complement(13105..14736)
                     /locus_tag="U2R64_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEM8917421.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSNIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            15042..15713
                     /locus_tag="U2R64_000576"
     CDS             15042..15713
                     /locus_tag="U2R64_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8917422.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQHGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKINNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKSI"
     gene            complement(16416..16771)
                     /locus_tag="U2R64_000577"
                     /pseudo
     CDS             complement(16416..16771)
                     /locus_tag="U2R64_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16788..16955)
                     /locus_tag="U2R64_000578"
     CDS             complement(16788..16955)
                     /locus_tag="U2R64_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917423.1"
                     /translation="MQTLINALQGKNYDYAVKILLDVAKRSLTPAQFAKFNAATIAAG
                     IAINAISCWGK"
     gene            complement(16955..17362)
                     /locus_tag="U2R64_000579"
     CDS             complement(16955..17362)
                     /locus_tag="U2R64_000579"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917424.1"
                     /translation="MSRFFKFFSLLGVMLIGLSTLVGAGTSVYAAEKVNEVPDIETQR
                     QQAVESLKFYLEEAGYVDTETHQYIVTDLEAIQKKAELDGSEGIAGKFILENFVQPTG
                     KRQKRDLQKYAACVVMNSLPFGVLFGIYLIVKI"
     gene            complement(17863..18057)
                     /locus_tag="U2R64_000580"
     CDS             complement(17863..18057)
                     /locus_tag="U2R64_000580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917425.1"
                     /translation="MKDQKTNNKTGERSACSWAFTGAGLLHSGIYTAAALGLSLTGVG
                     AAVIPFAVGTAYGIAGAAIC"
     gene            complement(18071..18409)
                     /locus_tag="U2R64_000581"
     CDS             complement(18071..18409)
                     /locus_tag="U2R64_000581"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917426.1"
                     /translation="MKRIVKIFGILGVFLIGLSTFVSAGISVDASETNNFLVKQQETE
                     INIIQNNLATHKDSKGNRLVYIIDESDLKSSLDRINSEITVSEIQQYLNEFNRSIQKK
                     WPWMANRSAS"
     gene            complement(18453..18785)
                     /locus_tag="U2R64_000582"
     CDS             complement(18453..18785)
                     /locus_tag="U2R64_000582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917427.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRKEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLVWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18799..19056)
                     /locus_tag="U2R64_000583"
     CDS             complement(18799..19056)
                     /locus_tag="U2R64_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917428.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KVYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(19251..19787)
                     /locus_tag="U2R64_000584"
     CDS             complement(19251..19787)
                     /locus_tag="U2R64_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917429.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLTTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDYMT
                     DRCIKDNSIDVDPHVQMKTTGKLHQVTQDIENPDQYLLFGEETTNEVTQFVLLQLKVD
                     QEAQKIDAIKIYYVRSVY"
     gene            complement(19808..20899)
                     /locus_tag="U2R64_000585"
     CDS             complement(19808..20899)
                     /locus_tag="U2R64_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEM8917430.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEDGGEATGLAVAFNWE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESTYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKDCYDYYGFLVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYQGAMSIIKSYNLTEYDTFAIKHWNSLPTKK
                     SSLVAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YDWTAYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSDGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20907..23117)
                     /locus_tag="U2R64_000586"
     CDS             complement(20907..23117)
                     /locus_tag="U2R64_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917431.1"
                     /translation="MAYIKRKEKKWCVWLFLTVGFGLFFVGGLVYAVEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYLLLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPAFDYMIMNTLKSFLSLMFQKSFYSVIILVAFLIY
                     NIVDDLILMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGGQVINPFELGGRSNQDLPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQSSKQQGNNQRKPLLNKGIAFVGQSIPLPAGKVPVPQLTAAGSLS
                     QQIHQVKNQAKNGSYPAMQQLLNQYSVPKSSVATLSGNRSVQRQIQRSSESKPSISVP
                     KSLQPAFSSFNNPVEQSKKIEKKNETLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(23133..25661)
                     /locus_tag="U2R64_000587"
     CDS             complement(23133..25661)
                     /locus_tag="U2R64_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8917432.1"
                     /translation="MVLVKEPVKALKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFYDVLNLIWLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRMPKEHKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEYKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTTIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAIGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVEYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILTHLRLEVNEANLSEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQIEEQDTLIMQ"
     gene            complement(25715..26125)
                     /locus_tag="U2R64_000588"
     CDS             complement(25715..26125)
                     /locus_tag="U2R64_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917433.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFFIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYVV
                     RMMNGDCVYYNWDKVSNNALEELLFANKYVYLED"
     gene            complement(26138..26356)
                     /locus_tag="U2R64_000589"
     CDS             complement(26138..26356)
                     /locus_tag="U2R64_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917434.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(26353..27345)
                     /locus_tag="U2R64_000590"
     CDS             complement(26353..27345)
                     /locus_tag="U2R64_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8917435.1"
                     /translation="MKKRQLRRKEKVYTEKVPNQRKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSQSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQEILKKEFYAQNFIQEPGSVSGIRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMDPENKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKTFIVKATVVFRDGDTSLLQKEQMTLVITKKTNQYYVEKLTHNWLDRKGDERK"
     gene            complement(27424..28335)
                     /locus_tag="U2R64_000591"
     CDS             complement(27424..28335)
                     /locus_tag="U2R64_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8917436.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLSDVETELNGGTTEKPAEPEHLQPEKPEKEPVAPEPEIPESTLPTDPIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSETNTDSSSTEQPTMSFTSEEPKEEPKQPAEKSEAIPK
                     ENKPIVPAKEVTVSVTPNGEITTNNSQGMSVPIVTSNVEELTHIPTPTTPLKAEGGQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVVLS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(28354..28698)
                     /locus_tag="U2R64_000592"
     CDS             complement(28354..28698)
                     /locus_tag="U2R64_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917437.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLGPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28718..29275)
                     /locus_tag="U2R64_000593"
     CDS             complement(28718..29275)
                     /locus_tag="U2R64_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917438.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCTIDEFYPREQDYL
                     AAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYECSVIQER"
     gene            complement(29355..29855)
                     /locus_tag="U2R64_000594"
     CDS             complement(29355..29855)
                     /locus_tag="U2R64_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917439.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPKEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPINFLKKC
                     HLRILP"
     gene            complement(29856..30401)
                     /locus_tag="U2R64_000595"
     CDS             complement(29856..30401)
                     /locus_tag="U2R64_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917440.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGTLKFIRFYRFSLPVPAILAVK
                     KGCDKMKIYENCVAALSNEKPLVEEISLATVTWEMNRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(30398..31654)
                     /locus_tag="U2R64_000596"
     CDS             complement(30398..31654)
                     /locus_tag="U2R64_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEM8917441.1"
                     /translation="MTPIELRNYRKKLSAIHASGGGKKLLSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKIVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKQTVTQNVLVQFSGQGCREYEEVMREQRTD
                     WRTWLYSIWKNQGKLEAGYKRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKKFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISEIEAL
                     TKYGIYNRYELRLANEKATQAVEAFILDHSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIENAELNDEQQSYLEWMGTSGGKIA"
     gene            complement(32017..32331)
                     /locus_tag="U2R64_000597"
     CDS             complement(32017..32331)
                     /locus_tag="U2R64_000597"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917442.1"
                     /translation="MGEVLYRVSSAAGEISPDFAVRRLYEWINKVEYYTKGSYVFRRI
                     ERETLFVTRNQIVLTKEDILRFRQVYRLCKEKNIQLRLAILQCFAPEQYKELQEKEDS
                     LV"
     gene            complement(32458..33651)
                     /locus_tag="U2R64_000598"
                     /pseudo
     CDS             complement(32458..33651)
                     /locus_tag="U2R64_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(33841..34197)
                     /locus_tag="U2R64_000599"
     CDS             complement(33841..34197)
                     /locus_tag="U2R64_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917443.1"
                     /translation="MNLDKTNQTLREIMVCCQNIQQLIEYFGDNPTIFIQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQDHQEVVWIRVVRICNMCAHPYKNRLNLFRLWFFIKCD
                     IPVLVAFCQKFLAQEK"
     gene            complement(34263..34715)
                     /locus_tag="U2R64_000600"
     CDS             complement(34263..34715)
                     /locus_tag="U2R64_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917444.1"
                     /translation="MGLKFPNNYDITEALDETCIGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNSNPKQSQEKGLDQKQPSADSKEKEKK"
     gene            complement(34717..35082)
                     /locus_tag="U2R64_000601"
     CDS             complement(34717..35082)
                     /locus_tag="U2R64_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917445.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            complement(35099..35293)
                     /locus_tag="U2R64_000602"
     CDS             complement(35099..35293)
                     /locus_tag="U2R64_000602"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917446.1"
                     /translation="MEKKNINICFLSGKECTYEECTDISVHERDGMLIVDMSPSDEPF
                     VVKHYFPLCNIESFRIDCEF"
     gene            complement(35310..35555)
                     /locus_tag="U2R64_000603"
     CDS             complement(35310..35555)
                     /locus_tag="U2R64_000603"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917447.1"
                     /translation="MEEIFFCMMVEFLFVSIGFLIMGEAIMIYLFPFDSKDECIFSSI
                     IIFFILACVWILAREIYHQFVLEDGKGIITWFLQKRK"
     gene            complement(36271..40566)
                     /locus_tag="U2R64_000604"
     CDS             complement(36271..40566)
                     /locus_tag="U2R64_000604"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HEM8917448.1"
                     /translation="MYAKTKMNWLKALALVALSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITTPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKLNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     TNRSVRVRRATNTAVLGGRKIDWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLLNNFDVRATFHNQTHTIKIGETLKVKSGNDFLQRV
                     KGIQKPKGINVSIHGNEAWITVTKEAPEKAKIHFNQIEVLGTPLAYRRPGAQTIGILN
                     PFEPGDSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KNMNGKVQAEIKDLDPGKYVLKEIKAPKGYALSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKIANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKERYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVT
                     FTLYNGKGQAIGKYTTDQNGEILVKGLVANNYYFTENVPLESFQPNTGKQAFTITFRQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQEGKEITSILTFIADKANGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAVHVDINDDNQSVRVNNPTVHTTAVFEDGLTIADPTGLFTLNDTVEINE
                     ILPGKAYLVKGILMDKATGEALLVHGQPVESAVGFIAKAENETVIVPFTFDLTGLNGR
                     EMVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLIVGKTYTVNGVLMDKVTEKPVLVDGKEVSSTLTFVAETTDGTVNLDFILD
                     AHALRSKEVVVFEDLFREGVLLASHADITDKDQTIKIVSPTITTKATNANGGKEILAL
                     PNQKVVEWVQVNGLAIGQIYKLIVQGYLTPDGTPFEGTHAEKVFMADKEMMEFLFEFI
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQFVEAPKPPQPVK
                     PNEPQPVKEVKQAAMVPMLPKTGSEDNVLWIMIGMIFVLAAGLIGYDLYKVRD"
     gene            complement(40713..40952)
                     /locus_tag="U2R64_000605"
     CDS             complement(40713..40952)
                     /locus_tag="U2R64_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917449.1"
                     /translation="MIDISIPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMIFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(41042..41314)
                     /locus_tag="U2R64_000606"
     CDS             complement(41042..41314)
                     /locus_tag="U2R64_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917450.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(41397..41648)
                     /locus_tag="U2R64_000607"
     CDS             complement(41397..41648)
                     /locus_tag="U2R64_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917451.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFVESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(42646..43557)
                     /locus_tag="U2R64_000608"
     CDS             complement(42646..43557)
                     /locus_tag="U2R64_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917452.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGQLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEISKESNRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFNKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(43754..45589)
                     /gene="lepA"
                     /locus_tag="U2R64_000609"
     CDS             complement(43754..45589)
                     /gene="lepA"
                     /locus_tag="U2R64_000609"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEM8917453.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            45736..46956
                     /locus_tag="U2R64_000610"
     CDS             45736..46956
                     /locus_tag="U2R64_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917454.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            46976..47470
                     /locus_tag="U2R64_000611"
     CDS             46976..47470
                     /locus_tag="U2R64_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEM8917455.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            47448..48134
                     /locus_tag="U2R64_000612"
     CDS             47448..48134
                     /locus_tag="U2R64_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917456.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(48285..50894)
                     /gene="clpB"
                     /locus_tag="U2R64_000613"
     CDS             complement(48285..50894)
                     /gene="clpB"
                     /locus_tag="U2R64_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HEM8917457.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(51145..52191)
                     /locus_tag="U2R64_000614"
     CDS             complement(51145..52191)
                     /locus_tag="U2R64_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HEM8917458.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(52202..52474)
                     /locus_tag="U2R64_000615"
     CDS             complement(52202..52474)
                     /locus_tag="U2R64_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEM8917459.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(52509..53417)
                     /locus_tag="U2R64_000616"
     CDS             complement(52509..53417)
                     /locus_tag="U2R64_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HEM8917460.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(53549..54781)
                     /gene="pepT"
                     /locus_tag="U2R64_000617"
     CDS             complement(53549..54781)
                     /gene="pepT"
                     /locus_tag="U2R64_000617"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEM8917461.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(54796..55917)
                     /locus_tag="U2R64_000618"
     CDS             complement(54796..55917)
                     /locus_tag="U2R64_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEM8917462.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(55914..56615)
                     /locus_tag="U2R64_000619"
     CDS             complement(55914..56615)
                     /locus_tag="U2R64_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEM8917463.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(56759..57199)
                     /locus_tag="U2R64_000620"
     CDS             complement(56759..57199)
                     /locus_tag="U2R64_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEM8917464.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(57328..58254)
                     /gene="dnaI"
                     /locus_tag="U2R64_000621"
     CDS             complement(57328..58254)
                     /gene="dnaI"
                     /locus_tag="U2R64_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEM8917465.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(58254..59627)
                     /locus_tag="U2R64_000622"
     CDS             complement(58254..59627)
                     /locus_tag="U2R64_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEM8917466.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(59650..60141)
                     /gene="nrdR"
                     /locus_tag="U2R64_000623"
     CDS             complement(59650..60141)
                     /gene="nrdR"
                     /locus_tag="U2R64_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEM8917467.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(60453..60785)
                     /locus_tag="U2R64_000624"
     CDS             complement(60453..60785)
                     /locus_tag="U2R64_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEM8917468.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(60837..61466)
                     /locus_tag="U2R64_000625"
     CDS             complement(60837..61466)
                     /locus_tag="U2R64_000625"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEM8917469.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            complement(61430..62266)
                     /gene="mutM"
                     /locus_tag="U2R64_000626"
     CDS             complement(61430..62266)
                     /gene="mutM"
                     /locus_tag="U2R64_000626"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEM8917470.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(62311..64956)
                     /gene="polA"
                     /locus_tag="U2R64_000627"
     CDS             complement(62311..64956)
                     /gene="polA"
                     /locus_tag="U2R64_000627"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEM8917471.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(65082..65765)
                     /locus_tag="U2R64_000628"
     CDS             complement(65082..65765)
                     /locus_tag="U2R64_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEM8917472.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(65758..66243)
                     /locus_tag="U2R64_000629"
     CDS             complement(65758..66243)
                     /locus_tag="U2R64_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HEM8917473.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(66550..67884)
                     /locus_tag="U2R64_000630"
     CDS             complement(66550..67884)
                     /locus_tag="U2R64_000630"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEM8917474.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(68015..68776)
                     /locus_tag="U2R64_000631"
     CDS             complement(68015..68776)
                     /locus_tag="U2R64_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEM8917475.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(68792..69274)
                     /locus_tag="U2R64_000632"
     CDS             complement(68792..69274)
                     /locus_tag="U2R64_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEM8917476.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(69294..71474)
                     /locus_tag="U2R64_000633"
     CDS             complement(69294..71474)
                     /locus_tag="U2R64_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEM8917477.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(71618..72349)
                     /locus_tag="U2R64_000634"
     CDS             complement(71618..72349)
                     /locus_tag="U2R64_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEM8917478.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(72418..73359)
                     /locus_tag="U2R64_000635"
     CDS             complement(72418..73359)
                     /locus_tag="U2R64_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEM8917479.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
BASE COUNT        21582 a        15408 c        11408 g        25120 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aaaaaaaaaa
     1321 taggctgtga cagcagcgtg acagcaaaaa agatggaaag ttaaatatca aacctcgtaa
     1381 tttcatttgc gagtgcttga tttgtttctg gatataagtg tccatatttg tccaaagtag
     1441 ttttaataga ggcatgacct agacgcttag atattgcata gatattttta ttatgttcaa
     1501 ttaaaaaggc aacatgcgag tgtcttaatc catgcatatg aattggtttt actcctgcaa
     1561 tttcagctaa tttttttatt ctgcttaaaa tagttcttgg agatggcggt aatccatcaa
     1621 aagaaaaaac caattctata tttttcccaa ttgattgttg agtttttttc catgttttta
     1681 aatcttcaac ggtttgtctg tctaacgaaa ttatccgaat acttgatgta ttttttgttt
     1741 cagcaaattc ataatcttgt cttgtacgga tgtaaattga cttatttacg ctacatctgc
     1801 catttattaa gtcaaagtct ttccattgta acgctaagag ctcctcactc cttacacctg
     1861 taacaaaaat aaaacgcatc aaacgtttat aaaattcttc ataaaaatcc ccgtgataaa
     1921 cactattata tactttctta aattcatcaa ctgtccaaaa ttctacttga ggacgctgag
     1981 tttttatttt acctatagta tctacaggat tttcttcaat aatttcaagt acaattgccc
     2041 ttttaaaaac tactctcaac ttattgaata tctgtttaat ataatttggt gataatggtt
     2101 gctcaatgcc cttttttaca acatggattt tcgataaaaa ctgttgaaat tcctgtatat
     2161 gaattggtcg aatctttaca acctgcattt ctccaaaaaa atccaatgca cgttgtaaaa
     2221 tatgatctgt tttcatatat gttttttcta cagttcccaa cttataccaa ggaaaaaaat
     2281 actctcgata aaaatcatga aacgttattc cttgcagaca aattccttgt gaatcagaaa
     2341 aactttgttt taactcttcg agtccccttc tagcttctcc ttgagttttg aagcctcttc
     2401 tggtcacttg aattcttttt ccaaagcgat cttgtcctaa agttgcagaa aaaaaccaag
     2461 tgcctctttt tctgtcttta taaacattcg caattttcct cattttacta ttcctcccaa
     2521 gaaatatgga gaacttcttc taaaattgaa ataggaattc tttttatttt tgaattacga
     2581 taaaaaaagt atcctttctc aactaaaagt tctttacatt ccttgaagat tttattagca
     2641 tagtactgag aaaaacctag attaatcaaa tcttttcgag tagctgtttt cattatagca
     2701 ccttccttac tttttttcat ttatttctat cagctgcttt tgtcaaaagc acataggaat
     2761 ttcacctctc cccaagttta cggcgagcct tacggaagta tcattatccc aactttaaat
     2821 catcgctttt tattgactat aaaaattatt ttagaatatt tatcgctcct tctttacagc
     2881 aagaaatcat ggcgcaacta aaatatgctc cttaaagtgt taacgtactg atagaatcta
     2941 tttaattttc aatgaacaat aggttttcta cctaaaagaa tctactaatt ccttaactat
     3001 tagaagattc ttttaaacag aaaaagtgga aaggagattt ttttaattag ttaattttaa
     3061 attttaagat cgcttctatt aatttaattt ctagctgact tatcatatat tcatctacat
     3121 aggtaacgaa ttgacctacc tcgttaaatc catttgtcaa acataactta gccatataac
     3181 tatgataatg tttgagtatc atcttgatcg aaattggatc tccttctaga gcagataaga
     3241 taatggatag tggaactaat aggtactgcc gctttttgga tttatctacc ataggtcata
     3301 ccccattttc aattgttcaa ctgccttctt tcgttgatac cagataccac ttgtgctcat
     3361 attgagaatt ttaccgattt cagcatcatt aaaacctgca aaataataaa gtaggataat
     3421 ctttcttctt atctccgata actgatcaat tgctgctgat aacttttgat ctgaaattaa
     3481 tatttccatt ccaaataaga aatagacatc ttgttcatca aaatgagttt gggaatacct
     3541 gccttcattt gaatctgcca atggttcctc attatccttt atgttagcat ttcgttttcg
     3601 aatagactta gcttcgtttc gtaatacttt tttacagtag gcatcaaatt ggtgttgtat
     3661 agatatgtca ttgtaatgtt gttgcatgat aatatgctcc tttttccccc tttccactaa
     3721 tacaacaatc agagagcccc tttttttcga aaaaactaga aaaaaacata aaaatattta
     3781 tcattcttta aacagaaaat ctttctataa aaaacaaaaa aacgattagg ctaggctaat
     3841 cgttttttga acattcttaa aaaaatccaa attatttttt ataactgaaa ttgggtattg
     3901 atgaccatcg tttctgtaga tagtgagcaa tcattttagg ttttctatct ctagtaaaga
     3961 ttcctttctt atttccttgc actcttaaaa tcccttgact cgttgcaaaa tctgcaaaat
     4021 tccacacttg ttcaccaaca aaattttcac atgtatctat tacttcgtga tttgcttcgt
     4081 aataagccac ttgatactct tctgtaaaca ttgttggtac tgtatcatga aatccagcta
     4141 ctgtatctgc tccatattct gtaaacatta ttggcgtatc aggacatctt tctttccatc
     4201 catctagctc ttttttcaac agatattttg catgtgccag atcccctccc gaaacatacc
     4261 aaccataata acgatttaaa cataaaacat cgacaatatc tcctacctta caaatatctg
     4321 gcgttgattt tagataagta actattgtta caggtctttt ctgcggatca agttctttag
     4381 ttaattcaac taaaggttca aaatattctt tagcaccttc ggaatccgaa tctggttcat
     4441 ttgcaataga ccacattaca acacttgggt ggttcttgtc gcgttctatc aattccttga
     4501 tcaccgtttt atgagaattt tctgttcgta tctctttcca cgtattatgt ttttccacat
     4561 tatcatctaa taaagtggcc atgaaattta aatgtaaccc tactgcaggt acttcatcaa
     4621 taactacaat accttctcga tctgctaatc gcataatttc ttctgagtaa ggataatgtg
     4681 atgttctaaa agaattagca cctatccatt tcattaaatt aaaatcttta atatttacag
     4741 cctcattcaa accacgtcca ttaacatacg aatcctcatg cttaccaaat cctttaaaat
     4801 aaaaaggttt attattaatc aaaaatttgc cattggtaac ctgaacactg cgaataccaa
     4861 attcttctgt ataggtatcg atcactttat tatcatcaat taaactaatt ttcatactat
     4921 ataaataagc atctagaggt tcccaaaaaa ttggattctt aagctgaatc attcctttct
     4981 ttccttcagc ttcagctaca agttgagcct cttcgtcata tatcgctatt aagatttttc
     5041 cggtccattc tgtatcgata ttgaattcta cacttgcatc caaatcagtt attcttgtat
     5101 taatagtaat atcacttata tagtctttcg gagttgtata taacttaaca ggtctatgaa
     5161 tacctgcata attgaagaaa tcaaaattaa ctaagttttc cttttttata tccccatttt
     5221 cctgtactgt ttccttcata atccccacag gtaaagtact atcgtcaata atattgttta
     5281 cagcaactgt aattcgatta ttcccgtctt ttacaaaccg attaatttca gactcaaatg
     5341 gtgtaaaccc acctttgtgt tgagtaatca actttccatt caaaaaaact tttgcttcat
     5401 gtgttgcaga tccaaaacga agaactaatc tttcttctaa taatctttta ggaagagtca
     5461 cttctttttc ataccacacc catccaacat gatttctaat gttctctgtt tcaaataaat
     5521 cattataaga agagggaact gaaatcggat aactctcttt ttcatttatt ggttctaaag
     5581 caagttcttc ctgtaagtca tcatttgtat ctaatttaaa tctccagaga ccgcttaagt
     5641 caattacttg cctcgtctct gtcataatgg gatacaacat ataaaccact cctatctaaa
     5701 tattaaataa atgtatcctt taaaccacaa taagcatcta ttggacttac tcccttaaat
     5761 tcagaaagac ccattagttt gtccaccaat atttctaaag tttcttgttt tccatcataa
     5821 gtattaatat aagtctttac ttgaggtaca tcagccaaat gaaacggaca ctgtacagat
     5881 acaaaaattg ttggaatttc atgaatgtaa aacggtatat ccggagttcc tttacttgct
     5941 ggccagacaa ttcgttgaac tgtgcctgga ttaacattag ctatattaat gatcaagtca
     6001 tattttttag ttaaattttt aattggtctc ttagcagcat atattccagc tatattttta
     6061 attttttctt cttgcgataa tcctttcaac tcttcttcag gtgaaatgta tttttcaact
     6121 tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa tggcttgagg tctatttcca
     6181 gcaactactt caccaaaccc accttttacc ccatgtacat ctactagtaa aatcctttta
     6241 tatttttctg gttcaatagg ccaaatatct tgtttatctt taactaatgt aattgcttgg
     6301 tcagccacct ctttaaaaat tgatttattt tcaattaaac caattttttc cagagcttct
     6361 tgcttaggta ataaaatttg ttcttttgct tttttgtgta atcccaattt agcttttaac
     6421 cctaaaattc tttttaaggc atctaataac cgatcatcag agataattcc tttacgataa
     6481 ccttccatca tataattaaa gtcttcatct ggatcattaa aaaatagaaa tagatcacat
     6541 ccagctgcaa tagaagtggg caataattct gatcgtttca ttgccccagt cattcctaac
     6601 atatgactag catcagtaac tactaatcca ttaaatccga gttttcctct aagtaagtca
     6661 gtgattaatt cttttgataa agttgcagga agtaaatctt catctttcag atcaggatta
     6721 aaatgttttg aataagctgg catatggata tgacctgcca taatcgaagg taatccagct
     6781 tctattaaac ctgagtatac ttttccaaaa gaattatccc attcttccgt acctaaacta
     6841 ttaatactaa aagatagatg ctgatctcgt tcgtcaatac cgtcaccagg gaaatgttta
     6901 gctgcaggca aaattccact ctcctgaata cctttcatat aagctaaact aagttctaaa
     6961 actttatcag ggttttgtcc aaaagatcga ctagaaatga taggatttct ccaatttcta
     7021 ttaatatcta caataggagc aaaactccag ttacatccaa tagccgatgc ttcaatccca
     7081 gaaactctcc ctaattcata agcatatttc gcatcatttg ttgcaccaat ttttacttct
     7141 acaccaactt cagtaccatc tgtacaagct ccgttaccac ctgcttccgt attagcagca
     7201 attaataaag gaattttgct ttctgtttgt aggatatagt tttgatcata tacctcatca
     7261 gcagttcctg ggttatatcg tacagctcca atatggtact gattgaccat attactcaag
     7321 taatttttat cacgactaga tcccatatta acaaacaatt gacctatttt ttcttccaaa
     7381 gtcatagaat caatcgtctc ttcaatccaa gaaatagcat cttcatctaa attatatggt
     7441 ttttttcgta agtctacttt tatagtcatt ttctttctcc tctacttatt agtaagattt
     7501 ttccaaaaag tatctataaa tttttgttca atatctacat actctcccga taaacattta
     7561 aataaaacat cagttcttaa gttttcccat gattcttttt ctttattaac caaaatagga
     7621 taaaagaaaa ctttattttt atttgcagct tctagatcac caggagaatc accaatcatt
     7681 aatatcttat ccaaatcaca accattttca attacacttc gaataatgtc ttcttttttt
     7741 cctttatctt gacaacacag ttcatcaact aatgataata attcatgtct ttcccattct
     7801 tcttgaacag cttccttatt agctgagctt acaataatta tcttcccata ttttttcaga
     7861 gcttttatag tatctctagc acttaaaaag ggtttatcta atcctttagc ttgactaatc
     7921 tgttgattga cttcttccga ccattttaaa gcttttaata aatcctctga ctgataatat
     7981 tctatttccc tcttcaaaga tggattagac aattcttttg ttagagatac ccagtgcttt
     8041 aatcgattaa tggatgttac atcatttttt tctaatgttt taactaaacc taaaaatctg
     8101 tttattccac gagtctctga atataaatta atattattcc aatcctgtag gaatttttct
     8161 ctatgatgaa catcaaaaat ctctgcagca attggtccga aaaagagatt gtgtttataa
     8221 gtcatcgtat ccataacaca gccatctgaa tcaatacaaa atatccaatt attcatattt
     8281 ctctcctatt tatatttttg ttttaaaagc tcgcaatttt ctaagacttt atctttagat
     8341 aatggataaa ggaaaaataa aattaatcct acaataaaaa aacaaattga tggaattaat
     8401 gttgaagcgt tatataactt ttctaaaaca tctcccgttt gtatatttgc taaagagtca
     8461 tagcctataa tagaaagagt ccaacctccg acgcctccag ctagagcttg acctattttt
     8521 ctagcaaaag aatataccgc atatacggtc ccatcttctc tttgatcaga ctttacttct
     8581 tgatcatcaa taacatcagt aatatttgcc caaataacag tattaaacac acccaaaccc
     8641 atatagccaa ccgaactaag aattaagaat acatacatat tactagtttt tatcaaaaat
     8701 aagatcaaat atactattgc tgaaaagaac attcctactg atgccagttc tttttttcca
     8761 tattttttac ttaaaaacaa agttaaaggt gaaacaacta ttaaaaccaa aataggattg
     8821 ataaaattca ttaaaactat tccctgtgca tcattatagt aatcaggaaa tacataatta
     8881 ttcatactca taattaataa ttgagcaagg agtaagaaaa tagccgcacc aattatagaa
     8941 agtaatgccc tatttttaac taaccctttt aaagatttta acaatgaaac tttgaattga
     9001 gattggtcaa ttcttactcg ttcagtagtt agtttataac atattaaata acaaataagt
     9061 gcacatatcg aaaatattcc cgcaacaatt gtaaaagttg atccaccacg aactatttga
     9121 gcgcctgaat catctcttgt ataaataaat aatggtgtta atacaccaat gatcaaactt
     9181 gctaaagtag ctccaacatt tcggaatgtc gatagcattg ttctttcttc tgtaatagaa
     9241 gtaatagctg atgccattga tccataagga atatttatag atgtgtaaaa aatactcccc
     9301 cataatatat acgtaacata catgtatact accttaacgc tcatagaagc tgaaatcata
     9361 gaagtttgat acattaaaaa acttgctaaa gcgactggac cactcattct taaaatccac
     9421 ggtttaaact taccctgctt agttgctttc gatctatcaa caatacgccc catagttaca
     9481 tcagtaactg catcgataaa tcttgctact aaaaataatg ttccaacggc agctccgctt
     9541 atccccaata cttttgtata aaagatcatt aaaaaagaac tagcaaaaat gaaagtaaaa
     9601 tcgtttccaa aatctccaaa catatatcct attttgtctc ttataccaaa ttttctttcc
     9661 atacaattct ctcccttctt ttgttaagcg ttttcattct tatgaaagta cgtactatac
     9721 tctgaagcgt aaagagtcag tatttatttt ttacatttca gagtattatt tgttttttct
     9781 cctaataatt ctttatctca taaaacttat ctatatattt actagctact cgacttactt
     9841 cttcaaaatc acctttttca acagaagcca ataaattccc acctacacca actgcaacaa
     9901 ctcctacttc aaaccaatct tctaagttct ctagacttac tccgccagta ggcattatat
     9961 ttacgtgtgg taatggagct tgataggctt ttacaatgga tggaccaaaa gcagaacctg
    10021 ggaatagttt aatgatatct acgccagcag taagtgcctc ctttatctca gtaattgtca
    10081 tacaacctgg taaataagga atttgatata aattacaaat ctcagctgtt tgtcgatcaa
    10141 aagatggact aacgatatat tctgccccag ccataattgc gatacgagca gtaaacgcat
    10201 ctaaaaccgt accggctccg attattacat ctttttgatc agcatatttt ttagcaattt
    10261 ctttgattat ttcttcagca ttaggaactg taaaagttag ttcaatccct ttaattccac
    10321 ccgcaataat tgaatttatt gctttaatgg cctcatcctt atttttccca cgtacaaccg
    10381 caatcactcc agccgcttct aacttactta aaatttctac ttttttcata tctatctcct
    10441 ctatctcctt cttttatgga tacatacttt gtctagctgt actaacttaa aaagaataaa
    10501 tttaagcttt tatttcaagt attattttct acttccgatt tcaaaaaaat taaaataatt
    10561 atacgcatta cgataacaaa tattctccac tatctgacta agatacattt catcatctgg
    10621 aattcggcct gctttaaccc actcgcttag taattgacat aatactcgac gaaaatactc
    10681 atggcgagga tagcttagaa aacttcgaga atcagtcaac atacctgtaa aattcgacaa
    10741 caaactttgt tgcgccatcg tagtcaactg ttgacgcatt ccttcagctg tatcattgaa
    10801 ccaccaagca catcccaatt ggattttttg aatcataccc ccttggaagc tttgcattgc
    10861 tgttgctagt ggaagccaat cagttggatt taatgaatat aaaattgttt ttggtaagca
    10921 cccactcttt tcagcggtat cgaacaatgc tacaacattt tgtgtcaaac tagcttgatc
    10981 ccccatcgaa tcaccaccga catctactcc aatttgttcc tttaatatac ttgaattatt
    11041 tcttaaagca tttaaatgca tttgcatcgt ccaaccatat cttgtatact cagacatcaa
    11101 atgtaattga atacctgtaa caaattgtgc aatttctgat aaatggaaat ccgtttttcc
    11161 tgctaaagct tttattaaca gattgtcgag tattttttca tctgctattt cataaaaata
    11221 agtattcaaa ccgtgatctg ctaatcgaca gccaatttga tgaaaatgat ccactcgttg
    11281 gctcaatgct tgcttcaacc cattaaagtc tttgattggt atagccgctg cttgactaag
    11341 ttttaaaata tagttcgaaa agcctgatga tttgatactc cagaccttat ctggacggaa
    11401 agtaggtaat accttgaaag aattatcctg tttagaaagc tcagtatgat accccaagtc
    11461 atctgtagga tcatccgttg tacagatggc tttcacatcc atcatctcca acaattcttt
    11521 cgggcgatag gaatccgttt ggattttttc gttagcacgt cgccaaattt ctggtgcatt
    11581 cttctcagaa attgtcaaat caatatcaaa gtaacgttgt aattccaaat gagaccattc
    11641 aaaaatagga ttacctggcg ccttctccac tgtttttaca aaagctaaaa atttttcata
    11701 atcatcacct ggaccactga tcaactcttc ttctatacca ttagctcgca tcaatcgcca
    11761 tttataatga tctccagctc ctttatcatt taaccatacc tgagtcaaat tcttgtattg
    11821 cttattttct agcaaatatg ctgggtctaa atgacaatga tagtcgataa ttggttggtg
    11881 ttttgcaaat ttatgaaaaa gtcttttagc tatttcattc tctaataaaa agttcttatc
    11941 taaaaacata tttaaacact cctttccttc cgttagtttt tagaagagaa aatttttcct
    12001 ctaaataaac tccattatat aattatttac tcgccccctt ttcaagcgct tcccaaatac
    12061 catttaaata aactgcacct agagctcggt catataatcc ataaccaggt ctaccggttt
    12121 ctccccaaat catccgacca tgatctggac gaatatagcc attaaatcca ttatcgtaca
    12181 ttgtttttaa tatcttatac atatctagag aaccatattc tgatttatgc ggcgcttcgt
    12241 aaaaatcgag tccattgtca cttaaatatt tgatattacg aacatgtgca aaaggaatcc
    12301 gatcccgttg acaaaattca gatagaattt catagacatc attatctggt cgttctgcaa
    12361 tacttccagt acataatgta ataccattag aaggagaatc cactacatta cacaaccaat
    12421 ctaaatcgtc acgattttta acaatacgag gtaatccgaa aatggaatat ggtggatcat
    12481 ctgggtgaac tgccatttta atcccaactt cttcacatgt cgggataatt gctttgagaa
    12541 aatatgcaaa gttctctcgt aatttctctt catcaacttc tttataggct tctaataatt
    12601 gcttaatttg tgataaccga tgaggttccc aacccggcaa ttcaaaatta ttagtagaat
    12661 tttctacttt tctaataatt tcctccggat cagtagggat attttttgaa atataggcta
    12721 acgtagaaga cccatcatct aaacgataat ccaaatccga ttttacccaa tcaaatactg
    12781 gcataaaatt ataacagata acctcaatcc caaattctgc caaattgcga atcgtctgtt
    12841 tataattctc aatgtattga tctcgtgttt gtaaaccaat tttgatatca tcatgaacat
    12901 taacactctc aataactttc aaggtaagtc cattggcttc gacttcatct tttaaagatt
    12961 taattcgttc tctcggccaa acctctccgg ctggtatatc cattaatgtt ccaacaattc
    13021 ctttcattgc tgggatctga cgaatttctt gtagtgagat tttttcttca tttgccccat
    13081 accatctaaa agtcatttcc atagttactt tcctccaact tctgttatat atttattgat
    13141 tgttttacga actgcttgag gacctactag catttcgcaa aagatttttt cagttttctt
    13201 tcctacccca acttgatata aatctaaacc aaaaatttct ttattttcta aaatttcctg
    13261 taccgcacaa tgaatatttg aaggatcttg ttcacctaat ttcaatactg ataatttatc
    13321 ctgcaactct accaataacg gatcaggact tggcacaaaa ttttcccctt gatcatcgac
    13381 tgccagtaaa taacgtaacc aagcagcaat agcgatagga ataaatgtta gattttctgc
    13441 atttccgtct ttttcgacat actttttaat tgtttcacca tagcgaatcg ctactttttg
    13501 agaagtatct gttgcaattc gttgtggtgt atctggaata tagggattag gcaaacgttt
    13561 attaattact tcatcaataa attgttttgg atcaataatg cctggatttt caactactgg
    13621 taaaccttct aaataaccta ttcctttgat taaaccaacc aaatcatcat cctgcatctc
    13681 tgctgaaatt gattgatatc ctagcagaca acctgttact gccaaagcag tatgaagtgg
    13741 attcaagctt gtcgtaacct tcatgatgtc tgctttatca accgtctctc tatctgtcat
    13801 aatcacacca gccttttcca atttaggccg gccatttgga aaactatctt caataactaa
    13861 ataatgaact acctcagtat tagtgaaagc agcaatattg gtatgttttt ttgtgtgaat
    13921 gatatctaaa tcctcgagcc ccatcatcaa tagatcttcc tttacattct ctgaaggatt
    13981 tggcgtaatt cgatcaatca tactccaagg aaaagtcact ttttctttat cctttaaata
    14041 agcaataaat ttttcagaaa catatccttc tttttgccaa gcttctgcaa tcgtaaaaat
    14101 actatcttga aaacgttgac cattctgtga gaaattatca gtagaaacca tcgcaatcgg
    14161 caactctcca gcattaaatc tgctatataa caaggatgtt acaatactca tcgtatgttg
    14221 aggattgcta ggtccagatt tgatatcagc tttgactacc gaaaagaatt gccctttaga
    14281 atcttttaaa ctgtaacctt tttcagtaat agtaaacgtt gtaaactgta atttaggatc
    14341 ttcaaaatat ttaaccactc tttgatagtc cgctatattc ttcggattgc aatataaact
    14401 atcagccgtt actgccaaaa gccttttttt gagttcacca tctccactca taacaatttc
    14461 caaaatgtca ttgttgtagt catgataagc tttttccact acttcttcat caaatgtttc
    14521 acacacaact actcctgttt ctaattcatt ttgatctgct aagcattgag caatttctgc
    14581 atgaaatcct cgataaagat ttcctccacc aaaatgaagc catactggat gttgctggcc
    14641 ttcttgctta acttctttga catcaaaaca cggcagtaga atctgcattt cattgaattc
    14701 ttcgatagaa ttttgccaat ttttaatcga aaccataatt aacctcctta aactaatatg
    14761 ttagttttga tacattttat attttaaaac ccgttgtaac cgttgtcaat ataaaaatgg
    14821 aataaacttg ctttttttct accatatcag aattattgta ttttttattc agaaaaataa
    14881 aatactcctt ctttttggac tgattttatc gaaacttatt tttttctttt tttcatgtat
    14941 tcttttattt ttataactag tgtattactt caaaatttga tattatatgg catgaacaga
    15001 attaaaatat cagctaaaat aaaagttaag gagcattgag tatgacaatt aaaactagtc
    15061 tccaaaatca agcttaccaa tctattcgcc gacaaattat ctatgctgac ttagaacctg
    15121 gaaaaaaagt atcagaaaaa aaattagaag aaacactttc tattggtcgt acaccaatac
    15181 gtgaagcact gattcaactc cgacaacatg gtcttgttga tacaattcct caaagcggaa
    15241 attatatctc attaattgat ttagattcgg ccaaaaatgc tcgatttgtc agagaacatt
    15301 tggaacgaca aattatgtta gagtgttgtg ccaaaattaa taaccaaaaa aaacggattt
    15361 tagaaactat aatttcagaa caagaaaaag ctgttagtca aaaaaatgct cgtagttttt
    15421 ttcataatga taatttattc cataaagctt gttttgaaat tgcagagcga gaagaagtat
    15481 ggcaatggtt agaaaataac aatacacact tagaacgatt tcgttggcta cgagtaaaaa
    15541 cggaaggatt aaagtgggaa aaaattatgg aacaacatta tcaactattt gaggcattaa
    15601 caaaacaaga tccagaagaa gctaactttc taacatcgtt gcatcttcat ttaatgctta
    15661 atgagcaaaa tattgtttta gctactcatc caaaatattt caaaagtata taacttttaa
    15721 ctctttttaa attaaatgat tgttctgatc agaaaaatat cgcttgtttt cttattatgt
    15781 aatatatttc ataaactatt ctgcataaca actattgttt gtacttttta cattggataa
    15841 ctaattatga ctgctgataa cttttgatat taaactagta tctccaatcc aaataaaaaa
    15901 tagatatctt gttcatcaaa attagttcat ggatacttac cttcatttac atcattcagc
    15961 ggtttctcat tttcttttat tctattattt cattttctaa tagacttggc ttcatttcgc
    16021 aatacttttt tacaataggc atcaaattgg tgttgtttag atatttagtt gtagttttgt
    16081 gacatgataa gtatgctcct ttttgtcttt tccactaata caacgatcaa agggtgcttt
    16141 tttcaaaaaa ctagaaaaat caaaataaga ttcgtatttt gattctatat atcctgtttc
    16201 aactacatct tatatttcat aatagaataa atagcctttt gcatagctgc ttaacttata
    16261 agaaattgca atttacttct tcaaagtgaa aacgaatatg agtaaaataa aattattctt
    16321 cttacagata attaaaaata gcgcgtaaca aaaatcggca ttcaatcaca taattaggat
    16381 tgatgccgat tacttatatt ctacgtatag ttttagtatt ctttttttat caccagtaac
    16441 caattgagaa cagtcctaaa gcagaatagt cttttatctc aaaacgctta atttcaggct
    16501 taggaatatg aataatcttt tgagtatatt ctttctcttt taatcttact gaagaaatac
    16561 cactgcctat cttttttaca aatatttcat ttggtgtaca gactaataaa acaatatttg
    16621 taatcaatcc ttgcactaaa gaattaaaag gaagactatt taaaacaggg tgtgcataac
    16681 tataacatgt gaagtagtta ttttgaactt taacttttaa aaactttaaa aataatctta
    16741 tttgttcttc taaacaatca tctatactca tataatcact ccactaatta cttcccccaa
    16801 caagaaatag cattaatagc tataccagct gcaatagttg cagcattgaa ttttgcaaat
    16861 tgtgcaggag ttaaacttct ttttgctaca tctaaaagta ttttaacagc ataatcataa
    16921 tttttccctt gcaacgcatt aattaaagtt tgcattagat tttcacgatt aagtatatcc
    16981 caaacaacac accaaatggt aatgagttca taacaacaca tgcagcatac ttttgaagat
    17041 cacgtttttg acgctttcct gttggctgca caaaattttc taaaataaat ttccctgcta
    17101 taccttcaga gccatctaat tcagcttttt tctgtatagc ttctaaatca gtaactatat
    17161 attgatgtgt ttctgtatca acataaccag cttcttctaa atagaatttc aaactctcta
    17221 ctgcctgttg tctttgtgtt tctatatcag gaacttcatt cactttttca gcagcataaa
    17281 cactggttcc ggcaccgact aacgtactta atccaattaa cattacacct aataatgaaa
    17341 aaaacttaaa aaaacgactc atttttatcc ctcctgaaaa gtattgttga ttatcaattt
    17401 ttatcctttt aagctgttca ataagacgtt tttacgttcc ttccgtttct attttattct
    17461 ttctgtctta taacagcttt tttcaagtaa agaacgatat aattcttctt aaaaaacagt
    17521 ctattttttc ggtatataat aaaattgtat tgttacctac atagcgaaac agtaccaaca
    17581 tcattcaaat gaagatagca aatttgcttc ttcctttttc ttaagtgact atttaaataa
    17641 ccagaaaaaa actaaaatca cactgatatc ccaaataaat tgaaataaag gaaaaagttt
    17701 ttttctacca tgatagtttt tcaaaaaata gaaactcgta ctatttaaaa gtaaaataac
    17761 tagcatcgta aagactactg atttatctaa acttctataa aaaagtgggc taaataataa
    17821 agtaattaaa aaatgaacta tttgatattg ttttttttca tattaacaga tcgcagctcc
    17881 tgcgattcca taggctgttc ctacagcaaa tggaataacg gctgcaccta ctcccgtaag
    17941 gcttaaacct agagcagcag ctgtataaat cccagaatgt agaagtccag ccccagtgaa
    18001 agcccaactg caggcacttc gttcaccagt tttattattt gttttttgat ctttcatata
    18061 attctcaact tcatgaagct gatcggttag ccatccatgg ccattttttt tgaatagaac
    18121 gattaaattc atttagatac tgttggattt cagaaactgt aatttcagaa ttaattctat
    18181 ctaaacttga ttttaaatca ctctcatcaa taatatatac taatcgattt cctttagaat
    18241 ctttatgtgt ggctaaatta ttttgaatga tatttatttc agtttcttgt tgttttacta
    18301 aaaaattatt tgtttcagaa gcatcgacac ttattccagc gctaacaaaa gtacttaaac
    18361 ctattaagaa aacacctaaa ataccaaata ttttaactat tcttttcata atttttccta
    18421 cttaaaaata agttattttt aaaatatctt gattatgaat tcatccccca aaggcctttt
    18481 aagattgata cagcagtccg ttcacttctt ttagacttgt catataagtc ttttaaatga
    18541 tcccatacca gactagtttg tctatctagc ttcaatccat taaacgctaa tgaacggttc
    18601 attttttcta ttactttaga taaagctaca gaaattttta taccttcaca acgcgcatct
    18661 tggatttcaa taatagtatc atcaattagt ttttgaattt ctttcctatc aacatattca
    18721 atcttagaaa gagaatcttt taaagctact aatgattcaa cgatttcttt tttctcttca
    18781 gacattctct tcctccttct agtgacccgt aaagccatgt agagcagagt ccattgaacc
    18841 agtaattaca ctatctacaa cgccattcca atttactcta cattttccat ttttcagatt
    18901 tgtcggtcca tacggataga ctttttgaca ttcaatgttc ggattatacc agataggatt
    18961 ataccattca gccgcagaag cagattcagt cgatacaaac aatcccacac caacaaaacc
    19021 aatacacatc acactatagc caattaattt tttcatctcg tatccatctc ctaaaaaata
    19081 gaatagttct tgtagttatt cataagacat attttttccg tttttgtttt atcctttctg
    19141 tcctataaca acttttttca agtaaagaat gacatacttc ttcttaaaaa aacagtctgt
    19201 ttttttctat tttttcggtg cataataaat atgagtgttc attttttatt ttaatacaca
    19261 cttcgtacat aataaatctt gatcgcatca atcttttgag cttcttgatc tactttcaat
    19321 tgaagtaata caaattgagt gacctcattc gttgtttctt ctccaaataa caaatattga
    19381 tccggattct ctatatcttg tgtcacctgg tgaagtttcc cagttgtttt catttgtaca
    19441 tgcgggtcta catcaatact attgtcttta atacaacgat ccgtcatata gtccctcaca
    19501 gcttgattgc gtttataaac atctgtgaaa ttactccatt ttctagcaaa atcttttaag
    19561 aaattttttg tcatttcatc tatttgttgc gctgtctcgt cttctaatga accaatttga
    19621 ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc gattgtttct
    19681 tctgtcgttg tcaattgtgt tttttgtttt tcagaagaaa accaatgaca accagtaaga
    19741 cctatcaaac ataaccaact aaatactaaa attattcctt ttttcacgct tctagacact
    19801 gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg tacgtgcgtt
    19861 gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag aaatgttgtc
    19921 cgccatctga aacatctgtt ataattccgg tgtgaccata gattccagga gacaatgcac
    19981 cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt gggttcatga
    20041 tcacttgcca accataggct gtccaatcat aatcttcccc tattaacatc gcaaacatgt
    20101 gtccagaacc cattaactgt gggccaccta gttgggatac ataccacgcc gtgccaccat
    20161 aacactctcc attatttacc gatcgtccaa tgatccgatc taaaactttc gcattacctt
    20221 tacttttccc tgcaacaagt gacgattttt ttgttggtag gctattccaa tgtttgatcg
    20281 caaaagtatc atattctgtt aagttataag actttatgat actcatcgct ccttggtaat
    20341 acggactgcc ttcggtaata cctgccgccg catagcctcc acgacctaga atcaataaac
    20401 aactcccagg atctttattg cccacacatt gattaaagtt gctttgactc gccaccaaaa
    20461 agccgtaata gtcataacaa tctttcaggt tcggaaactt catatagaag ccaccttcag
    20521 aaccaccaat cccccgtgca gaaccttgtg gatagggaca accaggaaac caggtaatcc
    20581 caaagaagtt tgtatcgttt cttccagatt gtgattgtcc ataagtcgat tcataaccta
    20641 attgagaaag aatcacactt ggtaataact gatactttac cgctgcaccg actgctgctt
    20701 gcgcatgttc atctgtgatc ggaccacgtc ctttaatctc tgaaaaaatc ggtaatcctt
    20761 cggtatattc ccaattaaaa gcgacagcta gacctgtagc ctctcctcca tcctcggaaa
    20821 gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa agcagacaac
    20881 ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt ttgaactgtt
    20941 cgtccttttg gtaaagtaaa atcggttcct ggttttgcgt ccaaaatcgg caatgtttca
    21001 tttttctttt ctattttttt cgattgctct actggattat taaaagaaga aaatgcaggt
    21061 tgtaaggatt ttggtacgga aatcgacggt ttactttcag acgaacgttg tatctgtcgt
    21121 tgcacagaac gatttcctga tagagtggct accgacgact taggaacaga gtattgattc
    21181 aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac ttggtgaatc
    21241 tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc agcaggcaac
    21301 ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct ttgattattc
    21361 ccttgttgct tactcgattg tgccaacgat tgtacctgtt gtttcggtct tactgaattc
    21421 atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt ttttgatttg
    21481 gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact ataaggcaag
    21541 tcttgatttg aacgcccacc tagttcaaag ggattaatca cttgcccccc ttttaccgat
    21601 tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc agaagcgagt
    21661 ggattcgttg ctcggtacac attccctgct aatcctgcac ctttgattgc caaattttgc
    21721 ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg acttgctatg
    21781 tttttcgtgt tatttatggt ttgatctgca gctcctaacc ctagtttctt taataaatct
    21841 ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt tcctaaaaaa
    21901 ccaaaaacag tattcattag aattaaatcg tctactatgt tatagatcaa aaatgccacc
    21961 aaaataatca cactgtaaaa agatttttga aacatcaagc tcaaaaagga ctttaaggta
    22021 ttcatgatca tataatcaaa tgctggaaca aaagaagcga gtaatgaaaa aggaatcaca
    22081 agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat cactacaagt
    22141 ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc tttataaaca
    22201 gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc ttctcctgca
    22261 gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc cttggctaga
    22321 aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt cccataattt
    22381 aacaatagat acggatcaac aacagccgct ttataataaa gttggcgcac tttttgaatg
    22441 gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc caattcatct
    22501 agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc atttaaccct
    22561 ttagtaaaag cttctccttt actaggtacg ttactaccat agccaaacca aaccattgaa
    22621 aaaatgacaa caaagagaaa tcgaataaac accatttttg cgtaatgttt ccctctaaat
    22681 atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc aataggatcg
    22741 tatattttcg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa ctcgttcatt
    22801 gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat caatttactt
    22861 aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc tccaaataac
    22921 attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc aatatgaaat
    22981 ttcccgatct catagatcga ttgatccacc tgtttttcta ccgcatatac caatccacca
    23041 acaaaaaaca gtccgaatcc aaccgttaaa aaaagccaaa cgcaccattt cttttcctta
    23101 cgctttatat aagccattgt ttcacctcgt ttctattgca tgattaacgt atcctgttct
    23161 tctatttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat ttcttcaaac
    23221 aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca acactgtcct
    23281 ttaatcatat ggctcatttc agataagttc gcttcattta cttccaaacg taaatgagtc
    23341 aaaatctttt ctcgctcact gtcttcatca aaagcgaaga caacaccaaa attccctttt
    23401 tctttatctg aacctaagtc gccaataaat tgtgtatcta gcactaattg attcatctgt
    23461 gaacgcccca cacgcgccat tgctgcaata atactacgtc ccgcgttcga attattaaat
    23521 acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt tccaaacatt
    23581 tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc atctgtatat
    23641 agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa aatcgttgtt
    23701 ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg taaaatcgaa
    23761 tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg ttccatttgt
    23821 tctaaatact cgaccacatg catcaagcca acttgttgtc cggcttcttt ttgaactaaa
    23881 acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc taacggactt
    23941 aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa acaaacaatt
    24001 ggatctaata cgccataatt acggggattt gtagcatcta acgtgacata actcattttt
    24061 tgcaaatgtt ccacaaacaa agggtaatgt ttctgataat acgggtcttg aatgagtttc
    24121 gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac attcataaac
    24181 gaactataca aaaagagcaa tccaactaaa aaggtcttcc ctttaccggt ttttccagtt
    24241 actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat agctagaaga
    24301 ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt tttttctcct
    24361 cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga ttccatacct
    24421 aattctgata ctgctgaaaa caaccattcg ccaattgctt ctacagttgt tcggtgcttc
    24481 caatgcaact gtcgacccaa tggttgccct aataaacatt tatagaacaa ttctcgttga
    24541 tcattttttg cacggtggat atggatagtc gtatgaagct gttgaataat cgttgcacta
    24601 ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat ccaatcgacg
    24661 acaggttggc cattatctac tcgttgcttt aaatgtttta ctaatccccg aacagttaat
    24721 aagcgttcgc taggttcttc atcgttttga accaattcct tatattctgt tttgaaccgt
    24781 tccgatagcc aatttagttt taaaccaata cctccctgtc ctttcaagcg tggatagtga
    24841 attttcattc gtaattctgc tgggaaagaa agatcctgtg caaattgaaa tagatcacag
    24901 tttctcatat tttcaggtgt ttctccaata ggtaacaacg ctaaataact agtccccaac
    24961 tcatcttcta attgaagaag gcctttatgt tccttcggca tacgtacata cgttccttga
    25021 ttgtctttca gtacttccca attattttgt tcttctactt tatgagccat tcctcgaata
    25081 tattgcagac gattgagata caacagctct ttttttacta agggacgaat agaaaagcta
    25141 taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa agtttctaaa
    25201 tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctacatctaa ccagattaga
    25261 tttagtacat cataaaaact ctccacggtt gctttttctt tgactttgat tcctaaaata
    25321 aaggaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc ttttgcataa
    25381 tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc aaatttcgtc
    25441 cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc tgctaaaagt
    25501 aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt gttttttgaa
    25561 atggttcgtg gaaaaacatg atagtaggcc cagatacaat cctcgccatt taacaaacaa
    25621 tttttcttta atgctttcac tggttctttt acaagtacca atagatctca cctcccaatt
    25681 aaaaaaagga acaaccagtt gattgtccct ttttctaatc ctctaaataa acatacttat
    25741 tcgcaaaaag taattcttcc aatgcattat ttgatacctt gtcccagtta taatacacac
    25801 aatcaccatt catcatacgc actacataac aaaaccaatc ccataaataa aaatgcactt
    25861 tttttccatc aggttttagt tttgccagtg ctaacacaca taaatagggt agccctataa
    25921 aaaaaacaac ccctgctggt ggaaaaaaag aaataaccca accaataaat gaacgtaaaa
    25981 ataaatattc aaagattacg accaataaaa aagttgctgc attgactaat gcaactggaa
    26041 atggaagacg ccaattgctt gtaatctgtt gtacgcgata aggctccgca taaacaatcg
    26101 aataatcgta aggttcccaa tccacttcac tatcctccta atccataaat aatttttcaa
    26161 tgattttacc aaacgcatca aatacacgcg ttggatcatt taagaagaaa tagactgcgg
    26221 cacctgctgc gatagatatt aatgcatttc ctacttttga tttcataaaa tttcgcaatc
    26281 ccagataaac aaccaccatt attaaaaaat agccaccttg cgttaatata aaatctacaa
    26341 ttcccttcag tgtcatttcc gttcgtctcc tttcctatcc aaccaattat gtgtgagttt
    26401 ttcaacataa tactgatttg tttttttcgt aataacaagc gtcatttgtt ctttttgtaa
    26461 aagtgacgta tcaccatctc gaaagacgac tgttgctttt acaataaaag tttttttcgt
    26521 ttctttataa cgcaatactt tcatctctac ttgatcaact ttagctgtct gattgagtcc
    26581 ttcaggttct ttcatcatgt atgacatatc ttttgcattg tttttcgcat acttatctaa
    26641 gaaatcttcc acaaatcctt ccacatcttt cgcttccgac gcatcaaccg tttcgtataa
    26701 tgtgtcatca taagtaatca ttcgttgttt ttctgtattc tttggtagtg ccgtaaaata
    26761 aggataagca ataatacgac agcccttgtt tgaaatagaa aagggaagat tgagtacttg
    26821 tgtgattgtc acacttgttt ctttcttatt ctctggatcc atcgagcgaa tatcataagt
    26881 tactttataa ctagctgttg gaatggtttc aatttctttt aatccaataa acgaagcagc
    26941 agttaatttt cgaatacctg aaacacttcc tggttcttga ataaagtttt gtgcataaaa
    27001 ctcttttttt aatatttctt gacgttgttg ttcttgttca tgattatcga atgtattcat
    27061 atacaaagca acaaaacgat tcataaagga ttcaatttca ggtgtgtacg ttaattctga
    27121 ctgactttgt acttctttct tttgtaattg ttggatttca tctttcaaaa acgacacttg
    27181 aaccttcgtt ttcatggatt gaaaaaatgc caagccccct gaaaaacaaa gaaataaaac
    27241 caaacaccaa atccatttca ctgctttttt tgaatggatt ttcctttgat tcggtacttt
    27301 ctctgtataa actttttctt tccgccgtag ttgtcgtttt ttcataagct actccttcta
    27361 gtatgttttt actagtacgt acgattgaca acgataagct tgtttttctg aaaaatagtc
    27421 cattcaatta ccctcatttt ctattccttt tctctttctt ttatatccaa caaatccagc
    27481 aatacttgtc aacactcctc ctagaacaga aagtacaaca tgtatttctt caccagtctt
    27541 tggtaagact tttgtttttc catctgctgt tttgacttca atattgccac ttggaagttt
    27601 ctttacagga atcgacaaat cctttaccaa attcccttca ctatcttgga ttaatggaat
    27661 tccatctttt acaccaacaa ttgtttgtcc accttctgct tttagtggag ttgttggtgt
    27721 tggaatatgg gtcaattcct ctacattact agtgacaatc ggtacactca ttccttgaga
    27781 attattcgtc gtaatttcac cgtttggggt taccgatact gtgacttctt ttgctggaac
    27841 aataggttta ttttcttttg gaattgcttc tgatttttca gcaggttgtt tcggttcttc
    27901 ttttggttct tcactggtaa acgacatcgt tggctgttcc gtacttgacg aatcggtatt
    27961 cgtttcagaa gaactggttg ttcctgattg ttctggagtt gtgactatac ttgaatccgt
    28021 tgttgttgaa ctgtgcacac cttcttcttc aattggatca gtcggcaaag ttgattcagg
    28081 aatctctggt tctggtgcca ctggctcttt ttcaggtttc tctggctgca aatgttcagg
    28141 ttctgctggt ttttccgttg ttcctccatt tagctctgtc tcaacatctg ataatccttc
    28201 ccctggcaat gtttctacaa tttctgactt aggtgtttct acagtttcat ctgcataaac
    28261 caatgaactc cctaattgaa acgaaaataa tgaaattcct agtgttgtta cgactgctaa
    28321 tgttgttttt ttcatgatta ttcctccaat tttttatgca attcgtgttt tgttcataga
    28381 cgccgcacta atattatctg aacgataaaa gaactcccgt ccgttttctt ctaacccaac
    28441 atatggatta tttttgaata attgaatcaa tagttcactg gtgttgtatt ttggatagtt
    28501 tgcaaaaaaa taatactgtg cttgtcgccc atccgaaaat tcaacaagta attcataacg
    28561 ataccgcttc aatccttttc gttgttttaa aggatctcta taccaacttg tccatcgttc
    28621 cgttcgtgga ccgagataga cacgatacac atagaacaat gccataccac ataccaccaa
    28681 aaataataat cgccacataa aaattccccc ttttcttcta cctttcttga atcaccgaac
    28741 attcataccc tcggtagaga tccgaaaaat ccatcattaa tttttcgtat aaacgttgtt
    28801 gcaaatagcg attgtttcga atacataatt cttcatagcc atcaatcact tgatcttctt
    28861 tctcatagca tcttgtagct ctatgacgct cagcttgcat gacataacca aactctgcac
    28921 catatcgttc taccgttaat aactgttgac tacgcaataa tgcaatataa caatcacaaa
    28981 aatgttcagc cgacatttga tttttctcac gtttgtgaaa taggtattct ttagaaagca
    29041 cattattcgt taaacaatct gataaatagc gataatctgg cggtcggtta ttttcatctg
    29101 tgaatttttc ccataataaa ctgattttta ttcgttcagc ggctagatag tcttgttcgc
    29161 gtggataaaa ttcatcaatc gtacaaagct tttttatcac ccgaataaac aaatccatat
    29221 aatgcgaaac gaactcttcc ttttcaattg gctctcctaa aaattccagt gacataccat
    29281 cttctccttc cttaaaaaat aaaaaagcag aaaccgattt ggcttctact tttctttcct
    29341 tttatagctc ttttttacgg aagaatccgc aaatgacatt ttttcaaaaa attaatcggc
    29401 acaagttcac gaaaacttgg agcaatttta gatagaatca cttccccatc ttgtaaaata
    29461 caatcataaa aatcatcagt tacttgatac ttacgcttct tacaataatt gataaaatag
    29521 tagcgatcat tttctatttc cattcgttgt tctactaagc gcatacgaac atcatcatag
    29581 aaataagcca caaatcgccc ttcaagttca cgtttttcaa tgggatactc ttttggtaac
    29641 aatctatttt ttcgtcgttt atacattgct ggatacctta gaagaagttc atccaaacgt
    29701 ctgtcagtat atggcaactg acgaatcaat gattccaatc gttctttata cagatagaat
    29761 aattggcgca agcaatagtg tactgcttct ggattttcta atactgttgg atcacgcgac
    29821 caatacgcac caacataaat cataattttt ttcatttaga caatcacacc agcaatacta
    29881 atcaccgatc cacaataggt agaacaagtg gcatagcggc cgatttcctc taattccagc
    29941 tcaatctctt ctaaagaaag atacgtctgt tcttctgttg gctggcgatt catttcccaa
    30001 gtaacagttg ccaacgagat ttcttccaca agaggttttt cgttgctaag tgctgccaca
    30061 cagttttcgt atatcttcat tttatcgcag ccttttttta ccgctaaaat cgcaggtacc
    30121 ggcaatgaaa atcgataaaa gcgaatgaat tttagcgttc cttttcttcg gctaaattcc
    30181 aactcttcga gttcttgttc gtacccctta cgaacttcta ataagcgtgc aatttcttgc
    30241 cagttttctt tttcctgata acgtccagcc tttaccgctt gttcaatata aggaactcga
    30301 aaacgaaaat aagacaaatc aaccatcttt tcatttaatg cttcaattgc agcctttaaa
    30361 tccaaaagac gcagccattc tgttgtcgta tatgcattca tgcaattttc cctcctgacg
    30421 ttcccatcca ttctagatag ctttgttgct cgtcatttag ttcagcattc tcaattcctt
    30481 cttgtacaaa gtctcttcct aaaatacgat ctgcttcttg taataacttt aatgtcggag
    30541 ctacttgttt caaaaaccag cgttctgaac gatctaatga gaatttttct ggctttacgg
    30601 taaaatccaa ttcttccatc gaacgaaaca attttgccca tcgttcatca acaattcgtg
    30661 catcactttc cagtcgatcc caaacaataa gttttgcatt aattaaacca acgccaatct
    30721 ctcctaaacg tttaggggaa tgatccaaaa taaacgcttc tactgcttgt gttgcttttt
    30781 cattagctag gcgtaactca tatcgattat aaatgccata tttcgttaat gcttctattt
    30841 ctgaaatttt ctcacgattc gcaatttcaa aacgtttttc gtagaaattg aaaaacaatg
    30901 gactctttcg cgatccaaaa tacaaggata acccttcgct tcggaaataa ccatcatcta
    30961 aaaaacaacc gccaatattc tgaaatttct taaagtccat ttctaataaa cctgcttttt
    31021 gtttttctag taattcaaag agatcaaaat gttcttctgt ttccaatccc caaagttcat
    31081 ctaacgcaat atcgaatcga ctacattgta ctcgtttata accagcttcc aactttcctt
    31141 gatttttcca aatggaatat agccatgttc gccaatctgt tcgttgttca cgcatgactt
    31201 cctcatattc tcggcaacct tgacccgaaa actgtacaag tacattttgt gttacagttt
    31261 gttttgaatg ccagaatacc cagatatttc cacgaacaga aagacaatca aaaagataca
    31321 agcccgtcgg acgtgtttca aattctgtta gatccattcg taacacacgt tgaatcacta
    31381 ttttgtagtc tgtcccaaaa aaggagagac gcaaatagtc gatcattgct cgaagatcta
    31441 ttccgctttt catatacaat cgaaagcgtt ccttgattcg tttttcgaaa tcctctggga
    31501 ttttcttttt tccttgttcc atcttcttta tataatctac cgagcatccc aataactgtg
    31561 caaaacgttt ttgagagagt aattttttcc ctccacctga agcgtgaata gcactcaatt
    31621 tttttcgata atttcgcaat tcaataggtg tcatattcta cctcctttat aaaataacaa
    31681 atttcgattt tcttaatctg ctagaaatcc cgatataaca ggtggtaccc cctaattttt
    31741 ctaaaaagga gtactccttc taaccttagc taaagccttg atataactga tttaaataca
    31801 cttttttatt tgtgttatgt tatttctgcc ccccatatta tatatcgggg ggctttacac
    31861 aaagaggccg tgcgcaagcg cacgacctct ttgtgggcac acatgccaag catgtgctgc
    31921 cacgactggt ctcggtggct tcgccgacac aagccgcggc agcacatact cggacaatgt
    31981 gttctcccat agtccctatg aaagccaccc cgatatctaa accaatgaat cttctttttc
    32041 ttgtaattct ttatactgtt caggagcaaa acactgtaaa atcgctaaac gtaactgtat
    32101 gtttttctct ttgcataacc gatatacctg acgaaaacgc aatatatcct cttttgtcaa
    32161 aacaatctga tttctcgtaa caaacaatgt ctcgcgctca attcgtcgga aaacataaga
    32221 accttttgtg tagtattcta ctttgttaat ccactcgtat aatcttcgaa ccgcaaaatc
    32281 aggtgaaatt tcacccgcag ctgaagaaac acgatacaaa acttcaccca tacttcacca
    32341 cttccttcta aattataaaa gtgtataact ttcctcatct accccatttg ttttcgtatt
    32401 tccttttaac gattgcgctt gacgatcaat ttgttcttcg taactagtaa acgcctcttc
    32461 tttcagtaca gaaaaatctt gcacaatcat tgtgtcaaat tttttaaatt cctcaataaa
    32521 gtgatagtct ttgtaaacaa atggcgcaaa gaattctaca ggcacatcaa aaccaggaaa
    32581 agcataccca cgaccaggtt gatctttgtt ataaaacggc ttattcttaa aatcctctcc
    32641 aaaagtcatt aaatagccaa tgggagataa acggccaaca gaaatacgga acgttaaact
    32701 atctcgaaca ccacttggaa aatattccgc atctggtcgc tgcatcgcta aaataacata
    32761 catgcctgct tgacgacctt ttaatactaa tggctgaatt aatttatcaa ctttgtttct
    32821 cgtttccata tccaacgaac catagaaagc tgcccattca tcaaaaaaga taaaatgcgg
    32881 cggtatccca taataagcat aatttttccc tggttcatac ttaggctctt tcatcgtttt
    32941 catataggta tatcgctgat tcatttcttg taacgcattt cgtaagcaaa taatcatttc
    33001 ttcattcgtt ttgtaaaaca catgtccttt gaatacatca atatcaccta atgccgctaa
    33061 atctgccgct ttcccatcgc aaatatctac tgtccctaca tctaaacaag ctttgatcaa
    33121 tgaatacaat aaataggttt ttccgccacc aatcgcacca gaaattaata gatttggcga
    33181 ttgatcatat acccaatcca atgttttcat taaatgaata cgtccatttt ctgctataca
    33241 ttgatcaata ggaatccgac cagaatcgga aagaaataca taattgattc gggctttttc
    33301 tcgttcttca cgaattaaat cacgcaaaaa tacttcggat aataagctac ccatttttaa
    33361 aaatcgttcg tggaaacggc caccatctaa aggaaaagaa accactaatt cttgtttctt
    33421 ttgataaaaa taaacttttg gtaatctcat tttttccttc gtttgtttct caccaacttg
    33481 cttctttgta taaacaaacc gattgtcaat taacattcga gcaagtaact gacgccaata
    33541 aacagaagca aaatatcctt cctttagtcg cgaccaacgc atcaaaccta aaattaatcc
    33601 actaaccagc aacaaataca tcacaatact gattccagga ataagataca tttgccaatt
    33661 cgaatacgta tttaaacgag gataaaatac tttccaacta aaccaactta atagaatcaa
    33721 aaatggtaac agaaagaaac cataataaca aaaccataaa taacgattga aataacgaat
    33781 tcgtcgacca cgatacttaa aaaaatgagg ttccaattgt cacattcctc ctttctgttt
    33841 ttacttctcc tgtgctaaaa atttttgaca aaaagcaact aatactggaa tatcacattt
    33901 aataaaaaac cataatcgaa aaagatttaa tcgattttta tatgggtgtg cacacatatt
    33961 acatattcgt actacacgaa tccaaaccac ttcctgatgg tcttgtttcc actgatacgg
    34021 taatgaaaaa cgaacaagat cacgtaaaaa catacactgc ccaataaccg cacaaatata
    34081 ctcatttgtt tgtataaaaa tcgttggatt gtctccaaaa tactcaatca attgttggat
    34141 attttgacaa caaaccataa tctctcgaag tgtttgattg gttttgtcca gattcaaaat
    34201 ctccccttcc ttctacctta aatagaaaga gtaggaagac ttcctcctac tctttaaaaa
    34261 acttattttt tctctttttc cttagaatca gcacttggtt gtttttgatc taaacctttt
    34321 tcttgtgatt gtttcggatt agaattattt gttggagctt ctactttctc taatcctttc
    34381 gcataaatca ctaaatctga atattcacga ttgccatctt gtgctggaat atataccaca
    34441 tgatattctg gatcaattaa tttcacagga tcacgtcgtt taaaaccagt caaatctaca
    34501 tctgctggaa atttaactcg tcgtgcaatc tttggttcat ctggatttcc aaaaactaat
    34561 tgtgctcgct gtgatcgaat ttctcccgta taatcgcctg tttcattatc aaatacacga
    34621 tcggactctt ctaatgcgcc aaagcgtacg gctcctatac aagtttcatc taatgcttct
    34681 gtaatatcat aattatttgg aaattttaat cccatcttac aaaacctcct caatttttac
    34741 accagttaaa aagacaccga catcttgata gccagttgtt cgacgctctg tttgtcccat
    34801 atcatttgtt tcacgactat tcactctttc tttacgaaaa acaaaataag cttcttcaaa
    34861 tgaaatacgt acctcttttt ctggtaatcg taatctttta tcctcttcag ctgtgagata
    34921 aacaaaaaaa gcaggctgtt cttctcgcga acattctgct tgtaattgaa catatcgccc
    34981 agacacacca ttaatttcct ttggtggatt aggttcccgt gaacccaata aaaatacctg
    35041 acctaaaaac tctttcttca tacgcaatgc tttttctgcc atatcatttt tcctcctctt
    35101 aaaattcaca atcaattcta aacgactcta tattacacaa tggaaagtaa tgtttaacaa
    35161 caaatggctc atcactagga gacatatcta ctattaacat cccgtctcgt tcatgcacag
    35221 aaatatcagt acactcctca tacgtacatt cttttccact caaaaaacaa atatttatat
    35281 ttttcttttc catattcttt tttcctccat tattttcttt tctgtaaaaa ccaagtaata
    35341 attccttttc catcttccaa cacaaactga tgatatattt ccctagcaag aatccacaca
    35401 catgctaaaa taaagaaaat aataatacta ctaaagatgc actcatcctt gctgtcaaac
    35461 ggaaaaagat atatcataat tgcctccccc ataattaaga aaccaattga tacaaacaaa
    35521 aactctacca tcatacaaaa gaatatttct tccaactctt ttacatcctt tctaactttt
    35581 tataaaaaag gagattattt ttataaacac ttttattcaa caactatttt caaatgaatt
    35641 acacattatc atctcaagta tagtttcaat cgtcactatt gtttggtcca tttctagctt
    35701 ttatttaaaa catcgctata caagaaaaaa gaaaagcact gaaaccctaa caaaagaaat
    35761 gtttattcca tttaaatctt caattgaaaa ttatctattt caaaaaatta caagaaaaaa
    35821 tattctagaa cgaaaacaaa caattcaaca tctaatccaa acagttgaaa ataaaaatat
    35881 agacttttat ttgccttatg aacttattta ttttgccaaa gaaatacaaa aaataattaa
    35941 cacaaataaa cattcgaaaa aaatcctctt caaagtacaa agaatgtatt ttgaattctc
    36001 atactgctac ctagcagaac taaataaagt aagaaagcaa ttaggagtag ctaaacgtga
    36061 tttcttctat agaaaaaaag aaactgtatt atcacataat tatattctat ctcttttgga
    36121 tccttaaatt cttatttatt acactcagta tttcttggtg tatcctcatg atcatttact
    36181 actcaacaca ataatttatt tgcctttgat aaaaaattct ttctaaaaac taaacaagcg
    36241 gctagttgcc taaccgcttg ttcgtcctct ttagtctctg actttataca aatcataacc
    36301 aatcaatcct gccgcaagga caaagatcat accaatcatg atccataata cattgtcttc
    36361 agagcctgtt tttggcaaca taggtaccat tgcagcttgt ttcacttctt ttacaggttg
    36421 tggttcgttt ggttttactg gttgcggtgg ttttggtgcc tccacaaatt gaaccgtttg
    36481 atctttgttt gttagatcga cgttatgttt tgcgacttct tcaaacgttt ctttttcatc
    36541 ttctgttttg gcttggagcc attccgcaaa actcaatcct tttcctgcaa ggttgcgacc
    36601 gtcaacgatg aattcaaaca agaattccat catttcttta tcagccataa agactttttc
    36661 cgcatgtgtt ccttcaaatg gggtgccgtc tggtgttaag tagccttgaa caatcagttt
    36721 gtaaatttga ccgattgcta acccattaac ttgaacccat tcgacaacct tttgatttgg
    36781 taaagctaag atctcttttc caccatttgc attggtagct tttgtcgtaa tggttggact
    36841 gacgattttg atggtttggt ctttgtcggt aatatctgcg tgagaagcca ataatacgcc
    36901 ttctctaaac agatcttcaa aaactacgac ttctttgctt cgcaacgcat gtgcgtctag
    36961 gataaagtct agattgactg taccatcagt tgtttctgcc acaaacgtta aggtacttga
    37021 gacttctttt ccatctacta gcactggttt ttccgttact ttgtccatta gaacaccgtt
    37081 gactgtgtat gtttttccaa cgatcaaatc gtggtatttc acagcgtctg taatggtgac
    37141 tttcgttaat ggattaacct ctttcaagcc agtgggttta tgtgtagccg ttgtacgtac
    37201 acttgggttc gttactcgta ccgtttgacc tttgtcgttg atgtctttat ggtttgctag
    37261 ttcttcgtca tttctaaaaa gactttcaaa cacgaccatt tcacgaccat ttaaacctgt
    37321 caaatcaaag gtaaatggta cgatcaccgt ttcattttct gctttggcaa taaagccaac
    37381 agcactttct accggttgac catgaacaag taaggcttca ccagttgctt tatccattaa
    37441 gattcctttg accaagtaag cttttcctgg aaggatctca ttaatttcaa cggtatcatt
    37501 taaggtgaac agccccgttg ggtctgcgat cgtcaacccg tcttcaaata cagctgtggt
    37561 atgaaccgtt ggattgttta cccgaacact ttgattgtca tcattgatat ccacatgtac
    37621 cgcaacttca atgccatcac ggaaaagttt ttcaaagaca acgattgttt gacctttcag
    37681 aacactagca ttaaccacaa attcaagatc ttttgtgcca ttggctttgt ctgcaataaa
    37741 ggtcaagata cttgtgattt ctttgccttc ttgtaaaatt ggcgcattcg ttgccttgtt
    37801 catcaataca cctgaaatag tgtattcttt gccgacaaac aggttggtat aagaaacact
    37861 atctttaatg acgatagttt ctaatggatc aaccactttt tcaccatcgg ctttatttga
    37921 cgcttgtgtt tctaattttg gtggaatcaa atagttacgt acagaaacca ataacgtttc
    37981 cccatcatct ggcgcatttt gtctgaatgt aatagtgaat gcttgtttgc ctgtatttgg
    38041 ttggaaactt tctaatggta cattttcggt aaagtaatag ttattggcaa ccagaccttt
    38101 tactaaaatc tcaccatttt gatcggtggt atatttacca attgcttgac cttttccgtt
    38161 atatagcgta aacgtcacac cggcaagtgg tgttttcttc ttgttccatt cttcatactt
    38221 gaacaatttt acacttttcc gtgcttgacg gttcgcaaaa tggatcactt tgatcggttc
    38281 tgtatcattg gtaatcgaga acactaatgg gttttgattc aaaacgtaat ttacgggtgc
    38341 tttgatttct tccaaacgat agcgctcttt tccataagta agtgtaccgt tagttaggaa
    38401 aaagcctttt tcattggttt taaagatatc cgttgtttct gtatcatttg gaatctccat
    38461 tgtgacataa cgattggcta aagtatcaaa aatcttgaat tctgtattgg caagtggaat
    38521 cacttttcct gtttcttgat ccactttcac cactttaaga cgttgttcaa ttactttatc
    38581 ttctaaaaca taatggaaag tttgcccatt ttcagaaatt gtgacttcaa gtggttcaaa
    38641 tagtttatac ccttcttttc ctttggtttc agaaagaatg taggtatcaa agacaacagt
    38701 atttttacca aaagtagcgt aaccatcatt gtctgtcaca acggttttca ccactttgcc
    38761 agttgttttt gacgtcaaag agatttcaat gccagctaat tttggtttgt tatctggatt
    38821 ggttgaatcg actaaatctt tattagcaat tttcactaaa tcaatggttc ctttgatcac
    38881 ttgatctttt gcggtcgcat tgacagtttt tcctggttca acaacaattt caattgtttc
    38941 atcagaaagt gcatagcctt tcggcgcttt gatttctttt aaaacatatt tgccaggatc
    39001 aagatcttta atttctgcct gtactttgcc gttcatattt ttcaaggtaa tttctttgat
    39061 ctttttccca tctgcttgat acaagccata caccgcattt tctaaagaag ctgcgccttg
    39121 tgctttcaca ccggtttctg catcttcttt aaagacacga atgtttccct gtttcaaaat
    39181 agtcaaattg acaacagagt caccaggttc aaaaggattc aatataccaa ttgtttgggc
    39241 acctggacga cgatacgcta atggcgtacc caatacttca atctgattga aatgaatttt
    39301 tgccttttct ggtgcttctt ttgtgactgt gatccatgct tcattcccat gaatagatac
    39361 attgatccct tttggctttt gaatgccttt tacacgttgt agaaagtcat tgccactttt
    39421 tacttttaac gtttcgccaa tttttatcgt atgtgtttga ttatgaaaag tagctcttac
    39481 atcaaaatta ttaagcagac gttgaatttc tgcttttcga cgatcataat caacacggat
    39541 atttttgatt gggatttttg tgcccaaagc ttcccaaatc ataaattgtg ccgcaatgta
    39601 ttgttcatcg gatttgtctt tatttgtgac atatcctaaa taagagatca agcttgtttt
    39661 tttccgtaca tttgaatttt tcaaatagtt ttccaaagca gtagctgtat aaacttgacc
    39721 ttctgcggct gagacaccag gctcaataca aaacgccact tgtccattaa tctcaaaacg
    39781 aaccatataa tttaaagtga agtttggatt gttcggacta gaagtaacac caatattttc
    39841 gccccaatca attttccgac cacctaaaac agctgtattg gttgcacggc gaacacgaac
    39901 cgaacgattg gttggtactg ttactaacag tgtaggtgta cctgtttttg gaatgtcctg
    39961 ctcttttttc ttttgatctt caatactagc cgtagattct ttgtttagtt tcgttggttg
    40021 attttgacta gctgcggttg aagagattgt tttttcaacg ttttcctcat tttttccttc
    40081 tttgtcagca gtagccgctg gttgttccac tgtttcttct attcgttgct tttcttccgc
    40141 ttgtttctca gaagactctg gcttcacaga aggcgttgct tcggcagctt tttctccttc
    40201 tggagtggac gtttctgaag caggggttgt aattgaggca gtttcttcaa ctggttgtga
    40261 agtaacagga ctattccctg ggtgttgtgt ttccccaatc gtctgatcga gagtcgtttt
    40321 ggaattaacc gttggcgctt ctgtcacagg ggcctgttca acagtggctt caccagctgg
    40381 gaccccggct tctgctggtt ggacttctgt cacttcagaa gcgacttggg caatggcttc
    40441 caccgtaggt tgtgtagccg tcgtttcttc tgcatgtgct tgagcagttc ccaccaagaa
    40501 acagaattga gataaggcca ccaatgcgag tgctttcaac caattcattt tcgtttttgc
    40561 atacacaaga attcctcctt ttcctgagaa ttttatataa taaaacaaaa caccgttacc
    40621 aaaagtgata acgacgtgaa ctgtctcttc tatttttatc tggcgctctt atctgaacac
    40681 atttcatcaa tgattttacc ctcccactat aattacagaa caaaaaaaga acctgcttcg
    40741 tggaaatcaa ctgtccattt cccaattgga ataccagctt tattggcaac ttcaccatca
    40801 ccaaatatca tgccatacca attactacct tcatccttaa tttctttcca accatatgac
    40861 atagcttcat ctaacgaatc aaaaatcatg ccactgttgc caattgttgc aggatctggc
    40921 ttaagatctt ctggaataga aatatcaatc acaccataat gatccgattc cccagtatta
    40981 ttgtcattac tagctactgg tttggttgtt ctactgactt attttgatac aacaagtacg
    41041 cttattcttc ttttacttct ccgttttcaa tttcccattc aaaccactcc gcaaagtctt
    41101 gcttaaaacc atctactcga tacctatttt gtaaataggc atcttctgac gtcgtaggat
    41161 ctaaataggt aggtttattc tctggacgag catagacacc tacccatgtt tcgtaatctc
    41221 cttcaaaata actatctacc aaatagcctt tttttctaag aatctcccga acttgatttt
    41281 taattattga tacttgttca aaaccatcac tcattctatc acctcaaata actctagatt
    41341 ctcataaata ttcccgacaa tttcaatcct atcaatgatc tctaacaaat cgctacttat
    41401 gcttccccat tcgtataaga atttcccttc cgcaaaataa attttccata aacttcttca
    41461 tgatcgtccc aaccaatatc actctcgaca aattccacgt tgttcttatc ttttagctca
    41521 gtaaatgcca taagttcaac atgttttcca acctcgaaac aatcacacca cccatcaacc
    41581 gttacacgtg tgccttcaat acctaagaaa ctttgtcctc gtgtattaaa cactaaaact
    41641 ttccgcattt tttgctcatt aattaatcac gcgcgaaatc taggaatcac aacttgttcg
    41701 cttcttcttt ataaaataaa aaaactccaa taatcggaaa ttactatctt ttcctcattc
    41761 cttttttaaa tcttcatact tcttcttatc tttgtcctaa cctaataaca caaattttga
    41821 agaaaaactc agtaaaacct gattcttttt ttatcttcac aacaaccaac tttttcttca
    41881 gatcctttta ctagaacttg tatacaaaaa ttgttgaatg ctgatacaat ttgcggttac
    41941 ttgaaaaaac gatagatgta aaaagataaa tagaatcatt tttttattct atatcagtct
    42001 atgattcatt gcttatcaat cacccaaccc attcgatgcc gtttttttaa gagaaattta
    42061 aaaaagaccg tacgaatctc gcattgtccg attacttttc tagaaaagat ccccaattct
    42121 gtataaataa ccctatcttc ttgttggttt cattttctca tataagaatt cagtcaatct
    42181 acccactatg accattacta cgtccaacac aaccgacata ttaaccacgt aagtattccc
    42241 tcacagatct ccgaatttcc atggtatgga ttcccatcct gacgctgcag aggacaacat
    42301 atttcatgtg gctctgtacc cttttgattt ggaaagacta caaatcaata ctcatctata
    42361 acttatcaag cgaactttcg ctaggcttct agtgattact aaattgttgg ataacatacc
    42421 tagcccattt tatctagctg gtattcataa cagttatttc ttgtattact tcttccgctt
    42481 gtgttgccat tgagcttgtc aaaaagttac ttagaaaaaa gctgccagta aagcaacttt
    42541 caacaaaccc tttttgtttc ttatcatatc aagaaacctc cttttataaa tttttctata
    42601 ataaaaaaac gtcgataact taataagtat cgacgtaaac tatttttata tcccgtaaat
    42661 caaaaattct aaagaaagat ttcctatata agcatattgg ataattcgat tagtattggg
    42721 tatatctcta ccattctcat acctatctat ggaccatttt gaaattgaag gagaaaaaag
    42781 ctttccaaac tcctcccttt ctagataata atctttccta attttcctca tccttaatcc
    42841 catactaaaa gaatttatct tgttaaaatc gctaactctt tcatcttttg gaagtatatt
    42901 cttataatct tctccgtaca taaggtaagg aacagtgacc ttaccaagat aggcaatatt
    42961 cattagtttt tcaatatctg gaatattaat acctttttcc catctactta taacattttt
    43021 gcctgtatag atggtaaagt ttttaccaaa tttttcaagc gtctcttccc ggttctttcg
    43081 gacttctcgt attctttttc ccataacaat tttatcgtct tttgataaac taaatatctc
    43141 actatcacga ttactctcct tcgaaatttc tttttcatta cttaatagaa aaatatcgat
    43201 ttttttttgc atttcttttg acggatttct ctttctattt aacacataac tgagtaatac
    43261 ttcactaatt cctatattat cagctaactc tttgttaagt aacttattca tatctctgta
    43321 tgcaattagt tgaccgatga gaatctcaat cttatcttcc tcatctttta ttagagtttc
    43381 tatattcaaa atcttgctta gagtattatc tacgtcttta gggatttttc ttgacccttt
    43441 ttcatattta actaaagtac tttgtgaaat acctgctaaa tcagctaact ttttttgaga
    43501 tagttttttc tcttttctta gagatttaag aacccttcca cttgaattat caaccatgaa
    43561 aaaagcacct cctatgagat gctttcatca tatactgaca gctaaaaatc ttcaagaaaa
    43621 aatattccaa ttttgttatt tttagtatcg ccgtgataac caaatgacag tttaaaatct
    43681 tttatacaga taatcctcag tgttgcatct actcaaaaag gttgatttaa taggtttttc
    43741 gattgattat aagttatttc acactatctt gctcatccat tttcagaacg gccatgaagg
    43801 cttcttgcgg aacttcgacg gagccgattt gtttcatccg cttcttccct tctttttgtt
    43861 tctctaagag tttacgttta cgagaaacat ctccaccata acatttagcc aagacgtttt
    43921 tacgcaaggc tttgatgtct gaacgggcaa cgattttttg tccaatagct gcttggattg
    43981 gcacctcaaa ttgttggcgt gggattagtt ttttcagttt ttcaacgatt gcttttccac
    44041 gttcataggc aaagtctcgg tgaacgataa agcttaatgc atcgactttt tctccattca
    44101 gcaagatgtc catcttcact aacttgcttt tttgataacc agacatttca taatccaatg
    44161 aggcatagcc tttcgtgctt gatttcaatt tgtcgaaaaa gtcaaagaca atttcagaaa
    44221 gcggaatatt atagacgaca tttactcggt aatcatctaa ataatccatc gtaatgaatt
    44281 ctccccgttt tcgttgagaa agttccatta ctgcaccgac aaaatcattt gggaccatga
    44341 tctgtgcttt gacgaatggt tcttctacat cctgaatcgt tacaggttca ggaaaatctg
    44401 ccgggttatc tactgtagca gtcgtaccat ccgttttatt aacatggtaa ataacggatg
    44461 gtgcagtcgt gatcaattct agattgaatt cccgttccaa gcgttcttgg acgacatcca
    44521 tatgaagaag tccgaggaat ccacagcgga acccaaaacc taatgcttga gaggtttctg
    44581 gttcgaattg taaagcagca tcattcaatt gcagtttttc taaagcttcc cgcaaatcgt
    44641 tgtaacgaga agtatcaatt ggataaagac cacaataaac catcggattc atttttcggt
    44701 aacctggtaa agcttcagcg gcaggattgt ctgctaacgt tactgtatcc cctactcgtg
    44761 tatcttggac agttttgata cttgctgtga tataaccgac atcaccgacc atcaaaaagt
    44821 ctctagcaac tgcttttggc gagaagaccc cgacctctgt aacatcaaat gttttgccat
    44881 tactcatcag tttgattttg tctccgggtt tgaccatacc gtccgtgatc cggacattta
    44941 gaacaacacc gcggtaacta tcataaatag agtcaaagat caaagctttt agcggtgcat
    45001 ctaagtctcc acttggtgca ggaacatatt ccacgatctg ctcgagaata tcttcaatcc
    45061 caatccctga tttggcactg gctaatacag cttcactagc atcgattccg attacgtctt
    45121 cgatttcttg acggacacgt tcgggatctg ctgcgggtag gtcgatttta ttgatgactg
    45181 gcaggatctc caaatcattg tctaacgcta aataaacatt ggccaatgtt tgtgcttcga
    45241 ttccttgtgc tgcatcgacc actaaaacgg caccctcaca ggcagcaagg cttcgagaga
    45301 cttcataggt gaagtcgacg tgccctgggg tgtcaatcaa gtgaaagata tatgtttctc
    45361 catttttcgc tgtgtaattg agttctacag catttaattt aatcgtgatt ccacgttcac
    45421 gttccaaatc catcgagtct aacagctgat cttgcatttc gcgagacgtc acagtgtgcg
    45481 tcatttctaa aatacgatcg gccaatgtag atttcccatg gtcgatatga gcgatgatcg
    45541 aaaaattacg aatctgctct tggcgttctt tcattttctt tatatccata gcgtctcctc
    45601 ttttcatata atcagcactt tccattatac caacgaaaag cagtaattta aagagttttt
    45661 aattagtcag ctatagaagt tttttttgta gaattttgct atactgttat caagctaata
    45721 aatggagatg aaaaaatgga tcaaaaagat tttagagaaa atcttgaatt aaaaccggtc
    45781 actcaagaac atatcgatca attcaatgaa ttgctttcct atgtgttcca agtgactgaa
    45841 gcagacatcg aggaaagcgg gtttgagaat aaacgagctt ttatccgttc caaaaaaccg
    45901 attttggaag tatcgaaagt gttcggatgg ttccacgaaa ataaactgat ctctcaaatc
    45961 gctatctatc cttgtgaagt caatattcac ggtgcacgtt ataaaatggg tggtgtgact
    46021 ggagttggaa cttatccaga atatgctaac catggattga tgcaagatct aattatcgtt
    46081 gcattggata atatgcgcaa gaataagcaa tggatctctt atttgtatcc ttacagtatc
    46141 ccctactatc ggcgtaaagg atgggaaatc atgtctgata aactttcctt taaaatcaga
    46201 gatacacagc tacctaaaca aatcccagta agtggtatgg ttgagcgatt accagttgat
    46261 catccagacg tattttccgt ttatgacaaa tttgcccaac aaaaccatgg tgctttattc
    46321 cgcagtgatt ttcattggga agagtattgg cgtttcgaaa atgaagatga gcgcacagcc
    46381 gctgtctact acgatagcaa ccatgaacca agaggtgttc tgttctactg ggtagctgaa
    46441 gaaatatttc acgtaaaaga aatgttctat cttgatcaag aagctcgaaa tggcttatgg
    46501 aactttattt ccgcacattt ttccatgatc tactgggtac atggagatat ttataaaaat
    46561 gagcctttag catttttgat tgaagatagt cagatcaaag agcagatcga accatatttt
    46621 atggctcgga tcgttgatgt aaaagaattc cttcaacggt ttccgtttgt tggaacagct
    46681 gatgcttttc atttcatcat tgaagatcct gtcgctcctt ggaataatgg tgtcttcgct
    46741 ttaacatggg atgaacaggg acaagtccgt gtcttaaatg aacctatagg aaaatccgtt
    46801 cgactggata tccaaacatt gacttgcttg atgatgaatt atcgccgtgc ttcttatttg
    46861 gcaagaatcg aacggttaga aacagatgaa gaaacactga agtcactaga gcgtatcatt
    46921 ccaaacatgg aagcttactt tagcgattat ttttgataaa aaggatgatg tttagatgaa
    46981 aatttatttt gccgcaccaa tgtttgctaa aagtgatttg ttatataacc aacagttagt
    47041 taaagaaatc agagagctct cttctgagct ttcgatctat cttcctcaag aaaatgaagc
    47101 aatcaatgac aaaactgctt atgcagacag tcgaatgatt gctcttgctg acacagaaaa
    47161 agtgttggct agtgatttaa tgattgcttt actagatggg ctgacgatcg atgccggggt
    47221 agcatcggaa atcggtgtgg cttatgcgaa aggcatccca gtgatcggct tatatactga
    47281 tactcgacag caaggcggaa cccacccgaa aaaaatcgct gcactacaag aaacagctga
    47341 aaatcaattt cactacctga acttatatac aataggtttg atcaaattga acggaaaagt
    47401 ggtttcttca gaaattgagt tgctttcaga agtaaaaaga tttttagatg gagggacttt
    47461 cagtgattaa agaaatcaaa aaggtgcaaa tagctttact tgcttttggt gtattcgttg
    47521 tctgctataa tttttatgaa tttatcacac aaaaatattc gacttctcaa ggaatcacat
    47581 ttatcgtgga atctttatta gggattgcat tgattttcat gccacaagtc attttgaaag
    47641 ttttcaaact taaaatacca gcagcaatcg ttttgtttta ctggtttttc ttgttcatct
    47701 ctgtcttttt aggcacaggg atgcatttga tcagtatcat ctctttttgg gacaaaatct
    47761 tacatgcggt gagtccaatg gtcctgacag ctcttggcta tggattgatt ggttacttga
    47821 tgaaagatgc tgagatatca aaaaccagtc cttggttgtt cctcttattc ggctttgcgt
    47881 ttgctggact ttgcggcgtg ttttgggagt tctgggaatt cttatgcgac cagttcttag
    47941 gcatgaatct tcaacgtttt gctgcttctg atggcacact gtttgtcgga cgagcagcat
    48001 tgatggatac gatgggcgac ttgctgacaa atacgatagg tgctgcctta atgggattgt
    48061 ttgcatggtc tcaaagtaaa aaagatgagc gttactttga aagttataaa ttagaaaaag
    48121 tgaaaaatac ctaataaaag aggttgtgac agaagcgggc agcttcaaga aatttcggct
    48181 tatttttcga agaaactact tctggaacac tgtttatttg aaaaaaggag gtctgacact
    48241 agttgtgtca gacccctttt ttcttttata gtctcaatgg aagattagac gatttcttct
    48301 agctcttctg ttttgaaatg aagttgtcca tcaagtaaag taatcgttac ttttgattta
    48361 ggcataacat gtcctgcaac gatttcttta gctagtggtg tttctacttc cttagtgata
    48421 aatcgtttca atggtcttgc accatatgct ggttcataag cattttcagc aatccacgtt
    48481 ttggcttcat cactgattgt cagcaggatt tcttgatgtt ccagacgttg tgccaattgc
    48541 gccaccattt tgtcaacgat tcctttcacg ttgtctaggc tcaatggtgt aaataaaatc
    48601 gtgtcgtcga ttcggttcaa gaattctggt ttgaagtttc cacgtaatag cgtgttgact
    48661 tgttcagcca ctgcttctgg aatcgttcca tcagcagtca cgccttccag cagtaactgt
    48721 gaaccgatat tgctggtcat gatcagaacc gtatttttga aatctactac tcgccctttt
    48781 gaatcagtca agcgtccgtc atctaggact tgtaacaaga tattgaagac atcgggatgc
    48841 gctttttcga tttcatccaa caagacgatt gtataaggat ttcgtctgac agcttccgtt
    48901 aattgaccac cttcttcgta acctacatag cctggaggag ctccgactag acgagacaca
    48961 gcatgttttt ccatatattc actcatatcg atccgtacca tatgatcttc tgagtcaaac
    49021 aagttctcag ctaacgcttt cgctaattcg gtttttccga caccagttgg tcctaggaaa
    49081 aggaaagaac ctagaggacg atttgggtct tgcaatccag cccgtgaacg aattaccgcg
    49141 tcactgaccg catcaactgc ttcatcttga ccaatcactc gtttatgaag tgtttcattc
    49201 aatttaatta gtttttctcg ttcaccttct acaagtttcg ttacggggat acccgttaat
    49261 ctgccaacga cttgagcaat ctcattttcg gtaacggact cttgaaccat cttaatctcg
    49321 ctgtcttttg ctttagcttc taattccttc aattcttttt ctaattgagg tatcgtacca
    49381 tgacgcaata cagcagcgcg ttctaaatca tagttatttt ctgcatcttc taattcgtgt
    49441 tttgctttat cgatttcagc acgttttgct gaaacagaat tgacttcttc tttttctgtt
    49501 tcccactgca tcttcatcgc atttgcttct tcacgaagtt cagctaattc ttcttgcaaa
    49561 tttttcaagc gttttttact tgcatcatct gattcttttt tcagtgcagc ttcttcgatt
    49621 tccaactgca tcaaacgtct agtaacttga tctaattccg ttggcataga gttcatttct
    49681 acccgaatcg ttgcactggc ttcatcgatc aaatcgattg ctttgtccgg taagaaccga
    49741 tcagtaatat aacggtcaga taaagtagct gctgctacta atgcgttgtc atggatgtta
    49801 acaccatggt ggatctcaaa acgttctttt aatccacgca gaatactgat cgtatcttcc
    49861 actgttggtt ctttgactaa taccttttga aagcgacgtt ccaacgcttt gtctttttcc
    49921 atatattgac ggtactcatc taaagttgtg gcaccgatca aatgtaattc accgcgagca
    49981 agcattggtt tcaacagatt tccggcatcc atacttcctt ctgtttttcc tgcccctacg
    50041 atattgtgga tttcatcgat gaacaagagg atacgtccat cacttttttt gacttctttc
    50101 aagactgctt ttagtctttc ttcaaattca ccacggaatt ttgctccagc gatcaatgca
    50161 cccatatcta atgaaaaaat cgttttatct tttaaatttt caggcacatc tttgcgtacg
    50221 atacgttgag caagcccttc aacgattgcc gttttcccta caccgggttc tcctatcaga
    50281 acaggattat tttttgtttt tcgtgaaaga atacggatga catcacggat ttcttcatca
    50341 cgaccgatga ttggatccat ttttccgctt ttgacttgct gtactaaatc aacgccgtat
    50401 ttttctaatg ctttgtattg ttcttcttgg ttttgtgagg tcactctttc tcctcctctc
    50461 atctcttcga tgtttttacg caattctttt tcagataatc cgtttttatt caaataaaca
    50521 gttaacggat aattttttaa tttcatcaac gctaaaataa cgacttccgt tgaaagaaac
    50581 tcgtcgccga agctttcacg tatttggtct gcttcattca ataatcgaaa gaaattctgg
    50641 ctgaggtttt gtccatattg gacgtttcca ccagaaacaa ctggatactc atccagtaga
    50701 cgatcaattt catgttcaaa agattcgaca tccaatccgg catccgtata gaaatttcga
    50761 ccaaaatgat taggttgtaa aaagattttc catacatggg caatgtcgat atcttgatgt
    50821 tttcgagtga ccgcaatctg ttgagcttca gcaatcgctt cttgaagcgt cgtagtcatt
    50881 ttctcaatat tcatacaggt ataccctcct aattaaaggt aagatcactt atttctttga
    50941 tctttacaaa aactattata tcgctttggt caattttggt caaaatatac acatggtttt
    51001 ttgacttttt ttctcgactt atataaatct taaaaaaaca aaattgattg tatgtatata
    51061 aaaaaagagc caaacaaacg taaaattatc ttatccataa cgtttttctt tgatttgata
    51121 aaaagggtag atcttataaa agacctaccc ttgattttct ttattctctt tttttacttc
    51181 tattatttct tctttgatca ctcttcgccg ttcagcaatc acatacacaa atccatagag
    51241 aaatggcaag ataaaggaac tgaaacgata cagtaaaagc gaagaaactg cgtcaactgt
    51301 tccaacaact ggtctgaata ataacaaata gacaaattca aaggaaccaa taccagcagg
    51361 cgtaggaata acccctgaaa gcactactgc aaagctgata aacgaaatgg tcagtagaaa
    51421 atctatttta ggatggtttt caatcagaat caaataagga agtacatacc aaaatacaag
    51481 ttttaacata ttccatagat aaatccgcaa tagcgcagtc ctgtcttgga taatggtttg
    51541 gaccgtttcc cttaaagagt agatctgctg attgcatgta tccacccatt tccgcaaacg
    51601 ctcactttta aataacttat tcgataagct gacaaaaaat atttgaacat tcaagctgac
    51661 ggacatcgcc aataaaaagg caacaatcac gatcgtcaaa aggataccag cgatgataaa
    51721 ccagatcatt gatggaccat tagaataaaa aagagagaat tggatgacca agccagctaa
    51781 tgcataagtg atcactgcca gtttgtacat aatcatatgg agtgctgtca cccctgctcc
    51841 ctgggatagc ttcattcctt ttttgttata aaaataaatc tccgagatca gcgttcctgt
    51901 accaaacgaa acgattcggt aaaacgcaat atagctagag gtcaagaacc catctttcgt
    51961 tgtaaaattc ggcgcgaaag gttcagcaat ttctttgatt gagcgccctt cagcgatttg
    52021 gtaaactgtc cctaatataa cagccgctgc caaaacaaca acactggtag acagcaattc
    52081 ggcaaagata tctgcaaatg attgattgat taaataataa ataatggcaa aaatcacaat
    52141 cagcaaaagc agattcagaa tgattttagt tttcgttcct ttagacgaca tctcctgctc
    52201 cttaatggaa aaaataaatg agaatcaaat caacaagtac acctgcagcg aatcctatag
    52261 taaacttctt tttccgagtt ttatgatgga aaacttttcg agagatcaat cctcccaaac
    52321 caccgcctaa caggctgaca aatatcaaat tattctcagg aacacgccag ccgctagttc
    52381 tagcctgatg tttatcatac cccatcagac aaaataagta aaaattcaca atgaaaaggt
    52441 aaaaccacaa aagattgtgt aacaatacat ccattactct tcttccaact ttctgttaac
    52501 tactatttct aagctttttc ttctttcttt ggtgaataaa ctgttaatcc ttttgataca
    52561 acagataatt caactggaag atcatctgtc gtgtctccat ccgttcgagt gcccacagat
    52621 ttttcctgcg cttggatttt catgcgtttg gctgtgaaat aagtaatgcc ggggatcgta
    52681 tagaatttgc ctctcatgat tctaggcaaa taaaaaataa atcggaaaat atctaaggaa
    52741 ggtacgatcg ttacatgaaa ttttccatca tctagggtcg ctgagtcgtc aaaatttgta
    52801 aaaccgccca cggagttaga catcgtgact gtcaacagtt gggattttcc tttccaatgc
    52861 tcctcgtctg tttctaaatc caaatgatat tttttcttct tcagcaataa cttaaaaaac
    52921 ttcttgataa agatccacga gccgtaacgc tgtttttctt cttgactgat ccaaactgct
    52981 gtatctgcta agattccgat tgtcagtgta gagataatga cttcatcatt gacttgacca
    53041 tagtctattt tccgtacatt gccttccagg atcacgtcag cagcttcttc ttttttgagg
    53101 ggaatctcaa gaacacgtgc aaggttgttg acagttccac ctggaagtaa tccgacatgg
    53161 tattgagata atgttttttg gaacgcttgg acgatatgat gaatcgtgcc gtctccacct
    53221 ataattacta aagtatcagc ttctatggct tctgctttct tgactaattc cgcatcatca
    53281 atcgatgggc cagtttcagc tagttctaca tataattctg gctgcttttc ttttacataa
    53341 tcttgaaacc agcgtgctaa tttctcaccc tcatctttcc ctgaactttt gttataaaaa
    53401 actagcagct tttccattct ttacctccta tttactcttc aaaaaagagg gcgggacaac
    53461 caattccatt gtcctgccct ttagccttag acagatgaca ttccatcatt gggacgaacg
    53521 ccttgtcata agctgttctt tttcgatttt aactctttgt gttcaattct gcaattttta
    53581 caatcacgtc tgttgctttt tccattactt gtaaagaaac aaattcgaat cgtccgtgca
    53641 tattttctcc tccggcaaat agatttggcg tcggaatacc catgtaagag atttttgaac
    53701 catctgttcc tccacgaact ggttcgatca ctggagagat accaagctcg atcattgctt
    53761 gtttcgctaa ttccacgatg ctcatatctt tttcaatgat ttctttcatg ttgtaatatt
    53821 gatcatacat atctactttg attcgttctt gatcaaatcg ctgattcaac tcttcttgga
    53881 tatgtgtgat ttgtgctttg cgtgcttcga atttttcacg atcatgatcg cgaatgatat
    53941 aactcataga agcttcttca ggattcccat ccaatgccat caaatggaag aaaccttcgt
    54001 atccttccgt tttttctgga acttcatcgg ctggaagctg attatgaaaa tcgattgcta
    54061 actgtagagc attgatcatt gtatcttttg ccgtccctgg atgtacattt ttcccttgga
    54121 tcgtaatatt tgcttgagca gcactaaacg tttcatactg caactcacct aaaggaccac
    54181 catcgactgt ataagcaaaa tctacatcga attgctcaac atcgaattta tccgctccga
    54241 caccgatttc ttcatcagga ccaaaagcca ctttgatggt accgtgaggg atagaaggat
    54301 tattgatcaa gatctccatt gcagtcatga tttccgcaat ccctgatttg tcatctgctc
    54361 ccagtaatgt actgccatct gttgtgatca atgtgtggcc ttcataattt ttcaaatttg
    54421 gaaaatcttt tgtattcaat gtatagcgtt cttccgcatc tagtacgatc gtagactcgc
    54481 catcatagtt ttcaatgatt tgtggattga ctcctactgc attaaaatct gctgtatcca
    54541 tgtgggaaat aaatccaatg gaacgcactt catgatcaac attgcttggt aatgttccca
    54601 taacgaatcc gttatcttca ttatagaaaa catcagctaa gcctaactct tctaattctt
    54661 ttttcaattc ttgcgcaaaa gcaacttgtg tctgagtcga tggagtcgtt ttgcttgttg
    54721 catcggagcg tgtttctgtt ttgacatatc gtaaaaaacg tggcaaaaga ttttcgtaca
    54781 tagtattctc tccttttaat taaattgaaa tgggtttgta tttgtttcag aaacgaaaaa
    54841 gttaatatcc caattttctt cttgtttcca agattcaaat ttctcgataa atcgttgctt
    54901 gcataacgat tcaatataat gaccgggatc aattgcaatc aacccagcgc tttgcatatc
    54961 atgagccgta tgataataga tatctcccgt gatatagaca tctgctcttt gggcgattgc
    55021 ttgcggataa aatttttcac cgcttccacc gcaaatcgca atgcgcttca cagaggattt
    55081 tgcatttttt ggctggacta ttctcagtcc atctagttgg aacgcttctt ttacttgttc
    55141 tacaaatgcc tctatagaaa tttcttgcgg caattcacct actcgtccta acccaaacat
    55201 ttcgactggt tcatctatag cgaaaagatc ataagcaggt tcctcataag gatgagctga
    55261 ccgcatggct tgaatcactt gtttttcgat agtttccggc aaaataacct caacttttgc
    55321 ctcttgaact tgttctgtct tccctacttt cccaatcgct ggttgtgcac cagcttccgg
    55381 agtaaatcga ccgtgtccaa tcgaggtaaa acttgtaccg gtataatcac cttgtgtacc
    55441 agcaccagct gcagctaata cttcacgcat tttctgtgca tgatccacag gtacataaac
    55501 ggccagtttt ttataatgaa tctcatgagt ctttactaaa taactctcca cttcaatacc
    55561 gagaagttca caaaaccagt cattcagtcc atcccaaata atatccatgt tcgtgtgtgc
    55621 tgcatagacg gcaatatcat gtttcaacaa atctgcatac attttttctt gtggctgatc
    55681 agtaaccagc cgttttacag gacgaaagat tggaggatgt ttagcaatca gcaaatcgat
    55741 ttttttcttg attgcttctt cgaccacttc tggacgaacg tctaatgtca tcattactcg
    55801 ttggattggc ttatccaatg ttccgatatg cagtccgact gggtctcctt cttcagctag
    55861 ccactgagga caatagcttt caaacttttg gatgaaagtg cgtccgctga ttgtcatggc
    55921 tttaaaacct cctcaatcat ttggatttcc tgctcgattt gtttttgacg tgcctcttga
    55981 ttagctgctt gtttgagctg ttcacggata gcttttcttt gttgaagctc tcttgtccat
    56041 tttgatttga agatctcact tttctcttca agcagaaatg gcccgaacat cagctccatt
    56101 tcattgtaag taactggttt ttgttctttt tcggctacaa tgatttcata tattttttta
    56161 ttttcttcaa gtattttttc tgattggatt ttatactgat tttcttgcag ccaagatcgt
    56221 aatgtacgct ctccgatgtt tggctgaagg atcaaacgtt cttgtccgct taagcgttga
    56281 ttcaacttgc cagcttctag gatatctcgg atcagtgaac ctcccatacc cgcaatcgtg
    56341 acagctgtaa taccatcttg tggctggata gcatctagac catttgcaag gcgtacggtg
    56401 atacggtctt ctaatccatc ttttttgact tgcttacgtg ctgattcata aggaccttga
    56461 acgacttcac cagcaactgc atattcgatt tttcctctta atatcaatgc aacgggtaag
    56521 taagcgtgat ctgatccaat gtctgctaaa cgagcggatt cagggacaaa gtcacccact
    56581 gcggctaagc gctgagataa atctaaatgg ttcatagctt cactccttct agataattat
    56641 agcattttcc aaataaaata aggagactag gaataaaaaa attcccatat ctccttaaaa
    56701 aatatacctt ttcgttctat aaaacaacat tttcttattt ttgaaaaaat gttattggtt
    56761 atttgttcaa tgaaacatca ataatcgaat ctccaggaac ttgcggtggg atagacatcg
    56821 tcatgatcgg catctcaact aatgtaaatt ggactttgtc accgattttc aattcattta
    56881 tgtccacgct tattttttca gcagtagcat ttaagatcac tccgtcattg ctgaatgacg
    56941 ttcccatatt cgctggatct tctttggcca tgacatcgac gagtttcaac tgaagcgttt
    57001 cttcttctgc ttctacttga gtaatacttt caatcgttcc gacaaatatg ctttgtctct
    57061 ccgttttcgt actgcttgtt tttactgttt gacccgcatc aatcgaatca acagaacctg
    57121 tgttgctatc tgcgctaccg cagcctgcta aaagaaaaaa tagaccaact acagatatac
    57181 tagaaaaaat agccctcata aaaaatcctc cgtttaagtt tctgcattac ttgttgcggt
    57241 gattgtctcc ggtcatttct gtccatataa tgattcgctg acctgctttt actactaggt
    57301 caaatgtcag ttggacttgt caactgttca accattgcgt cggttgcgac cagtcatttc
    57361 gatttctttt gtcaaataac gtatgcgttc cattatccgt ttcgctttta gcggctcttc
    57421 atctccacgt tgagtgacgg acaaatgctg ttccaattca tccattgtaa aattcgatga
    57481 gaagaaggtt ggtaactgtt cctgcatccg atattgaagg ataacaccga atacttcgtc
    57541 tcgtatccaa ctactcatcg catctgcacc aatgtcatcg atcatcaaaa taggtgaacg
    57601 tttcactgca tctaactttt ctgccacttg atcttttccg attgcctgtt tcatctcaac
    57661 ggcaaatgtc ggaaaatgga ctagcgtcgt ggtgaatcca gcaatcgcta attctctcgc
    57721 tgttgctcct aataaatatg tttttccaat accaaaactt cctactagat acagtccttt
    57781 atgataccct tttggatcag cagtatattt ctctacaaaa tctagggctt ctaagctcgc
    57841 atatcctcgt ccatctgtac gttcaaagtt ttcaaaagaa gccgattgaa tatcttttgg
    57901 catatccatt gcttttactc ggcttctgat ttcttcttgt ctttgccgtg ctaacaatgc
    57961 ttccgttggt acataagtga catccacata atgaaaattc aacgtcagct tcggctcata
    58021 gccgggagcg atcatcgttg gatcgttttt ttgatattta cgcttttctt gcacgaattc
    58081 atacaattta gcgtaacttt tttcaatatc cgcttgtgtc aattcttctt ggtgtgcgct
    58141 tagaaaagct tgaacatccg catcatttaa gacttcagcg atcatttcag catacttttc
    58201 ttgataattg cgtttgctga tgatcctctt caattctttg cctacgtctt ccactagata
    58261 tcaccctcct tttttgccag gtattcttta aaacggcggt caatctctgc ttttttctcg
    58321 ctgctgatct gtttttcatc ttttggctgg ttgacccaat caggaagctt ttcccgtcga
    58381 acatttcgct tgccagtttg ataatttgtt tgcttctttt gttttgattg ttttgcttga
    58441 ttacttattt gccgaatgtg ctggatcgct tcttctgctg tggcgatttt cttttgtgcc
    58501 cattcatttg ccactgtatt tacataactg gcatttaagc tagcattatt cttgatcact
    58561 agtacataat tcagcaaaac attgatcacg ctactggaaa gacctgattg agaaacaaga
    58621 tcttgcagta accagttttc ttgtttagaa acatatccgc ctttttctga cttgattgct
    58681 tccagatatt tcatcggtgg aatgctctgt gcttctttta tcagctgaag cgctgcgttt
    58741 gtcaaatgtt cgtttgacga gggttcatta ctgttttcag aaaccgcaac tgtttctttt
    58801 gtttgcttca ccggacgtct ctgcattgcc aaaatggctt tttgcagttc tttttcagat
    58861 actttttgtt cactaaagtc ataagattga ctgatcagtt cgccaagtgt caattcatcg
    58921 aaaccgtaaa gctgatgata catgtcgact tgtttgatga ttggatcatc aagacttgca
    58981 atatgttttt ttgccagcca atcattcaaa aactgccaat cgaatgtcga atctgcttca
    59041 agtaatgcta ctgattcaga ttcttcaaaa gatttattca gcgattcgat gttttcttga
    59101 ttagcagcgt acactgcttc attgaagcga taaacatcta aaaatttttt tgtgattttt
    59161 tgatatccct ctgctgtatg ccttttaggt tcaaagaatt gggtaagctt ctggaatcgt
    59221 cgttcaccaa ctttttccag aagaagaaaa gccagaacag agtctttgaa aaatgcttta
    59281 ggaatgagtg gttctaacag ctcataaata aaacgaggtc ccagatcact atcttcttta
    59341 aaataaacat ccagtaagcc gattccttct agcttttttc ttgcatcata aaattgcggg
    59401 ataccgcagc ctagactact aagcagatct gcatgcatcc cttcaggacc tttgccagat
    59461 tcttgagaga tttctgataa cagggtgaaa tagatactca aggcttctcc gccgattagt
    59521 ggctgataaa gatacagcaa ggcgttcttg ctgtcttctc tcagcggagc cgcttttctt
    59581 ccttggtaaa tattttttgg ttgaagctct ttccaagcat tttccaagga aatgcctcct
    59641 ttttgtttct taattgtttt ctttattatt ctctttatta ttttcttttg ctttatccac
    59701 gatatcttgc aactctttta agaaaacaga catatctttg aactggcgat aaacacttgc
    59761 aaaacgaata taagcgattt cgtctaaatc aactaaatct tccatcacat attcaccaat
    59821 tagattcgtc gatacttcgt tttctccgag actgcgtacg cggttttcga catggttgac
    59881 gatttgttcc atttgttcca tagctacagg tcttttttct gctgaacgga tgagtcctct
    59941 taaaatttta tcgcgattga actcttcgcg ttccccgttt ttcttgatta ctaataacgg
    60001 agcagcttca attcgttcaa atgtagtgaa tcggaacgaa caattctcac attcgcgacg
    60061 gcgacggatc gcacgtccat catctgcttg acggctgtcg attactcgtg aattattatg
    60121 ttgacatctg ggacatctca ttttgtctca cctcttgcat cgcattttat ataaaggatg
    60181 tgtctttctt tacaactagt tgtattataa cacgaaacaa atcacaaacg cgactgtcct
    60241 acccaaaaaa cacggatata agaacaattt tttctacttt catgcgtaat tgtgtcccct
    60301 gtccttacta aatttcaatt ttccaatact gatcaccttg attactgaga aataacttac
    60361 acaaaagctg atttagtcat ctagcacaaa aaacttgaag cagatgaaca ccttctcatc
    60421 tgcttcaagt cacatctcga ttttttacta ttttataact tctcttcgat tcctgtatag
    60481 tgtttcattc gctgttcctc gattttttgc tcatcggaaa tgtggtcact ttctgggagc
    60541 ggtgttttac tacgatcagg tgtcggattt tttcgttctt gagtcaaatc ttgccgcttc
    60601 gcttcttctt ctgcctgctg gtcttctatt tcatcgattc ttgcttggta ctgcttttct
    60661 ttttcttctg ctgtttctga ttgcgtacga ccttcatcga ttagattttc tttattgagc
    60721 atctcgccga ttttttcttt tgcgttacct acgactttat ccttttgatt ttttaatgat
    60781 cccatcgcta tccctcactt tctatatact caggatagca aaattgacac agatactcaa
    60841 agaaagcgat tagcaaaaag ccaattttcg atttgtccca caagtttttc ttttgttcca
    60901 ttgttgtcga acaaaatatc cgcacgctgc tttttttctt cgattggaag ttgactacta
    60961 attctctgct gcgcttgttc tagcgtcagt tgattacgtt tcatcaaacg ctgaagctga
    61021 gtttctggcg tagtataaac gacagctact gcatccatat agtggtcata atgaccttcg
    61081 tagagcaatg ggatatctac aattactaaa ggatgattgg aacttagaga ggcgatttga
    61141 tcttttatcg cttttcggat aaacggatct aatagctgat caagtttttg ccgtttttcc
    61201 tttgatggaa aaacaatcat cccaagtttc cctcgatcta gttgcccatc aggctgcaat
    61261 acctcttggc caaacactga tacaattttc ctcagagcaa gcgttccagg ctcaacagtt
    61321 tctctggcaa tcacatcgcc atcgatcaaa ggaaatccat gagactgaaa gactttggct
    61381 gccgtacttt taccggtagc tattccaccc gtcaaaccta aaacaaatcc tactttgcga
    61441 tttttagcct ttgacaattc ggacaatagt gcgtccccct ttgtgccact tttgttttca
    61501 cgatcggcgt tccacaacgt atacatggtt tgccagtttg ctgatagaca tgcagtgcta
    61561 cttgaaatcc gcctgattct cctaatgcat tcaaataact gcgaatcgtg gtacctccgg
    61621 cttctattgc acgatccaaa acatcaatga tcgatagacg taattgttct acctctttgg
    61681 ggcgcagtgt gttcgccggt tgttctggat ggatcttcgc ttcccataat gcttcatcta
    61741 cataaatatt acctagacca gtcactagac gttggtctag cagcaatggc ttgattgctt
    61801 tgtgggactt tttcagtcca tttgcgaaat ctgctaataa gaagctatct ggcaaaggct
    61861 caggtcccaa tttcatgatt cctcggtaag ttgcacttgc tcctttttcg acgattgtca
    61921 tacgaccaaa ttttcgtaca tcgttgtagc gaagttggct tccatcctca aaaaagaaaa
    61981 gtacatgcgt atgtttatcg attggtgtat tttctttcgt aaattgatat tttccttcca
    62041 ttcgcaagtg tgagatcagt tcacaatgat cgagatgaaa aattaaaaac ttccctctac
    62101 gtccaatgga ttggatggtt tcgccaacaa gagaagcctc aaagatgggt gtctctggtt
    62161 gctcgatgat cttgggccac aagacctgaa ctttttgaat cgtttttcct actactaacc
    62221 gttccaatcc tttacgaacg gtttctactt ctggtaattc tggcattttt tcttttcacc
    62281 ttcattatat tgctctgtct taaacaatgt ttattttgct tcgtaccacg tttttcccca
    62341 actgctgtca gtgatcagtg gtacatgaag agaaacagct tgttccataa cttccttcac
    62401 caatttatct aatgattcaa gttctttttc cggtacctcg aagacaagtt catcatgaac
    62461 ttgtaacagc atcgtagctt gaagacctgt ttcttttaat cgtttatcca attcgatcat
    62521 cgcgattttc aaaatatcag cagcacttcc ttggattggt gtattgatag ctgttcgttc
    62581 cgcaaaagaa cggatattgt aatttcttga attgatgtct ggcagatatc gacggcggtg
    62641 atacagcgtt tcgacgtagc cttggtcttt tgcttcgcgt acgattcttt ccatatattc
    62701 tttgacacct gggtattttt caaagtacgt atcgatgtat tgctgtgctg cttttcggct
    62761 gattcctaga ttttgtgaaa gtccgtaatc agagatgcca tacacgatac caaaattcac
    62821 tgcttttgcc tgcctacgca tatttggtgt gacatcctct gccttttcga ttccaaatac
    62881 acgcatcgct gtgctggcat ggatatcttg accttctagg aaggcagctt tcaaatgttc
    62941 atcatttgag atatgcgcaa gtacgcgtaa ctcgatttgt gaatagtcag aagaataaat
    63001 cagccagtct ttttctctag gaacaaatgc ctgacgtatc tttctccctt catctaatcg
    63061 aatcgggatg ttctgcaaat taggatcaac agagcttaat cgtcctgttt gggtcaatgt
    63121 ctggacataa cgggtatgca cttttccatc tgattggatc actttcagca gtccctcgac
    63181 ataggtagat tgaatttttg caatttgacg ataggtgagg atatcctcta cgattggtgc
    63241 ttgttcacga agctgttcca gtacatctac ggctgtggaa tatccagttt ttgttttttt
    63301 gataacgggt aatcccattt tttcaaataa gatcactcct aattgctttg gtgaattcaa
    63361 attgaattct tcgccggctt cttcgtagat tttttgttcg atctctctta agcgagcaga
    63421 gaactcgccc ttcatttctt gtaagcgagt cgcatctact ttgatcccgc ttatttccat
    63481 ctctgccaaa atgatagaca atggcagttc cattttccgg aaaagatctt cttggttttt
    63541 atctgccagt tcttggctca attttggtgt caacgcattg attgcagcta cttttcgcgc
    63601 taaatgagca aaaaagagtt cctcttcttc tggtaaacct tttttcgccc ctttgccgta
    63661 tacagcttca tctgattgga tatcgttgta tccgtaatga gcagctattc cttcgatatc
    63721 tgtgcttttt tcattcgtat cgagaaggta tgcacctagc aagacatcaa aatcgattcc
    63781 tttcgttttt ccagtatagc ggtttaaagc aacataagtt cgtttcgcat catatacttt
    63841 tttcagccga gtcggatcag tgatccaaga atggaacgct cggttttcga atacagatag
    63901 atcgttcgtg acataaattt tcttttctgt cccccacgct actccgacga tttcctctgt
    63961 atgataattg tcgcccatca tttccacgta caacgccata tccgtagtaa acatttcctc
    64021 tttgaattca tgaacgactt caaacaaaat atcatccatt tttacttctt cttctacgat
    64081 attcaattta gaaaggaact gattgaaatc catttcttta taaaacggaa cgagtttatc
    64141 gagatttttc ccttcatact tcaatgagtc gatagagaca tccacaggcg ctgaagtatt
    64201 gatggtcgcc aattttttcg ataagaaagc ctgctctttg tcatttatca gattttcttt
    64261 cattttgctt tgcttcattt catcgatatg ttcataaatt ccttcgactg agccatattg
    64321 tttcaatagc ttgatagctg ttttttcacc gattttagtc acaccgggga tattgtcaga
    64381 ggcatctccg gctagtccct tcatgtcaat aatctgtttt ggcgtcaacc catcatattt
    64441 ttccgctaca tgttctggtg tatagctttc gatatcgctg acacctttta cagtgatatc
    64501 cacttttact tctttactag ctaattgagt caaatcccga tcacctgaaa gcacgacgac
    64561 atcaaattga tctttgtcta ctttttctgc caaagtaccg ataatatcat ctgcttcata
    64621 attgggcaat tcgtaatact gtacccctag tcctgtcaac aaatcacgta tatatggcat
    64681 ttgttctttg aattcgccag gtgttttgga tcttccacct ttgtactccg catacatttc
    64741 tgtccgaaaa gtcgtttttc ctgcatcgaa cgcaaccaga acatgagtcg gttgctcttt
    64801 ttgcataaca ttttcaaaca tcgtattgaa tgcatagatt gcatttgtat gaagaccgtt
    64861 tctatttttg aaacgttcaa gagaattgtg aagcgcaaag aatgcgcgaa aagccacact
    64921 gttcccatca acgagtaata atttattttt tgtcatcttc ttaactcctt actgtaaagt
    64981 tcttattcat tctaacaaag aatcctgcgg aatgcgaaaa gaaaaagcgg gaccatacca
    65041 aataattcgg tatagcccca actgatgaat ttttttcttt tttagttgtt ccgtccaaag
    65101 attctcagaa acgccaagaa caagttgata aagtccaaat acagcttcaa tgccatgaat
    65161 acagcaattc cactatgtgc tgttccgttt gtctggacat agatattacg gatgctttgg
    65221 ttatcataag ctgtaatccc tgcaaagatg acgactaaca gtagggagat gaacagctca
    65281 actacgctac ttctcaaaat gaagatgttc aagactagtg caatgatcac tccgattaaa
    65341 gctgcctgtc ctgctcttcc aaccccgcta agatctcttt ttgttgttac tccgacaaca
    65401 gacatcccca tgaacatcaa agtagctgtc aagaaagctt gcgttactgt tccaatatcg
    65461 tagtatgcaa gagtaaccgc taatgttatg ccattcaaaa gagagtaggc aataaatcca
    65521 ccgattgcta agctcggatt cttttgtgct tttacgccta gaaccattac taaaatcagt
    65581 tcaacgatcc acagacccac aaagcctagt ggaaaattat tgataaaagt tgctaattgc
    65641 aaaggaaata cccaaagagc caagtaagaa gtgactgcac taagggcaag tcccatacct
    65701 aaaaatccat aaacttttgc ataaaaacga ttgatacctg acattgatgt acttggatta
    65761 ttcattcaat tcaccttcac tttcgattgc tatttccaat tcaggaactt gtggcggttg
    65821 gaccataacg acagcatcca acacacgatc ttcgttcgta ttctccgctt ctacagaaat
    65881 cgtcaccaca tccttcatct tatctacttt tatgacctca aactgaaaag tcagtgtttc
    65941 ataatggaaa accggttcaa taaaattgac agaaaaattg acaacatgtg atcctggtcc
    66001 aggaagatgc tttgaaattg cacttgtgat gatccccatc agcatcactg atggaacgat
    66061 tggctgttga tattctgttt tttgtgcaaa gtcatgttgg atatacaaag gatttgcatc
    66121 attcgtcaat cccaaataca gcaaaagctg gttatcttca atagattctg ttaaggataa
    66181 cgagtcgcct tcctcgattt catttattgt ttttcctagt tttctcggct tacctatgtt
    66241 caagatagaa accctccagt ttatttttaa tcatacatta ttgtaccaaa agtagcgtaa
    66301 aaggcaagtt ctgctccctt gatttaacag attcctatag tttacagagg tcgtgaaaaa
    66361 gctgtcctgc atcaaataat aagaacagcc aagaaaaaac agcttctcat gtttttgatt
    66421 tgattgggct tattaccgca gatgcaagct tttgaacacc gtttatcata agttgcaaaa
    66481 aagggggctt ggcaagattt ttgccactcc ccctctttct atttttataa ggacactgca
    66541 gtaattgtat tacagtacat ttttcgtcgt gctgcttaaa agtttttcat acgcttgttc
    66601 aaatttttga acatctccag cacccatgaa gattactact gcatcatgat aatctaacaa
    66661 tggagataca ttattttctt tgatgacttc tccacctttt ttgattttcg ctccaaggtc
    66721 ttcaatctta acgtttcctt gttcttcccg agccgaacca aaaatatcgc ataagtaaac
    66781 tttatcagct aaatcaagtg cttctgcaaa ttcatccatc aatgcaatcg tacgcgtaaa
    66841 cgtatggggt tggaaaactg caattatttc tttatctgga tatttttggc gtgcgccatc
    66901 aatcgttgct ttgatctctg cagggtgatg cgcataatca tcgactacgg tcatgtctgc
    66961 tacgatcttt tcactgaatc gacgttttac tcctgggaaa gtcagcattt cttctgcaac
    67021 ttctttcaga tccagttttt cgaaataagc tactgcaata acacctaaag catttaagat
    67081 attgtgttta ccgaatgctg gtacagtgaa gtgcccaaca aattcatccc catgatagac
    67141 atcaaaagca gaaccagaag ttgtgcgttc gatgtttcgt gcttggatat catcgttttc
    67201 tgtgacacca taataataaa tcggcacatt tgcttttaat ttgcgtaaat aagcatcgtc
    67261 accatacgca aaaatagctt ttttcacttg tccagccatt gtttggaaag ctgtaaatac
    67321 atcgtcgata cttgtataat aatccggatg atcaaaatcg atattggtca tgattgcata
    67381 gtctggtgaa taggcaagga aatgacggcg atattcacag gcctcaaatg aaaagaattc
    67441 cgcttgcgga tcaccatgtc ctgttccatc tccaattaga taacttgttg gacggacacc
    67501 actcaataca tgagagagca gtccagtcgt acttgttttt ccgtgagagc ctgttacagc
    67561 gatactcgta taattttgga taaaatgacc aataaagtcg tgatagcgaa tcacttccaa
    67621 acctaattct tttgctcgct ggatttcttc atgtgaatca ggaaatgcat ttcctgcaat
    67681 gatcgtcatc cctggtttta cattatctgc gttaaatggc agaatcgtga tatttgcttt
    67741 ttctaaatct ctttgtgtaa agaaatattt ttcaatgtct gatccttgga catttagacc
    67801 ttgttcatgt aaaacaagag ccaaggagct cattcctgaa cctttgatac caacaaaatg
    67861 atacaattta ttttgatttt ccatttgaat cctcttctct tatctagcgt ccattctttt
    67921 agctattaca ttcaacacgc tcctcattat cttataaacg attgaaaatt tcaaccaaat
    67981 ttatttggaa aggaggattc gcttgctaaa atggtcaagt acgagaaaaa tccgttttta
    68041 ttgactcttt aattctggtg taagaagacc aaacttcctc tgatatatca atgtgaggaa
    68101 taaaatcttt tcctttcgga ccatagccgt tctcatcgtc atggagacgt tccatttctc
    68161 ctaatactag cgcatggaaa tattccttag gccattgatg attcagttct tttgctgtaa
    68221 agatgatctc ttcagaaaag tgaaggattt ccggcacaaa tggcacagca ttcgcgaaaa
    68281 tagtttgttc attttgccat actttctcaa aagttgctcg agtcctgcgt tgcagtgtcg
    68341 gatcattcat caataagatt ttttctggta cagctcctaa ggaatgaaga atctccagtg
    68401 aaaaagtggc gttctctcca gaatttgtag acttcgattc tatcagaaaa gccttatcgg
    68461 gcaaatcata gacttctttt agatactgac gacagatttc actttcactc atgccatctt
    68521 caaaatgaaa tccttgcttt tcaaaattct cataaaggat tctagtcgca tgccccaccc
    68581 ctccgaccaa aaacaattga tctacttggc catttaaata catttgtgct gctttatcag
    68641 ctaagatagg aagacagttt ccagctaaaa taagtgtagg tgccgtcagt tcctcaaaat
    68701 ttccctcttc aggtgcggct aaaaaattta atagctgatt ccagtctttt agattcctct
    68761 gctcactttt ttccaaaggc cttctatcct ttcatctgat tttttgtgct tcattaaagt
    68821 cttctctttt tgtctcaatc catttgattt ctccatgaca tcttccacaa cgatatttgc
    68881 gtacatcgat tcttctcttg cggcagatcg tggcagaaca atcttggcat cgataatact
    68941 ccatctttat ctgtttcttc gtcaaggctg gtgcatagcg caaccctcct gtttttttca
    69001 aaagatactt gaaatccata tctttatgct gataccctct tccagctaga tgaagatgat
    69061 aatggcaaag ttcatgtttg atgattcctg caatcgtctc ttcgtctgac tcttcaaata
    69121 gcttcgcatt aaaatctaaa tgatgatcgt ttaaatgata gcgcccgcca gttgtacgta
    69181 agcgtggatt gaacattgct tggtgcttga aaggaagctg gaagcttttt aatgatatct
    69241 cttctactaa ctgctgcagt tcttcttgtg tcaatttttg ttactcctca ttgttactct
    69301 tcataagggg aaagcatcgt caaactgatt ctgccttttt tcgtatcgac ttgttctatc
    69361 caaactgtta cgatatctcc tactgacacg acatctgtag gatgcttgac gaattttttg
    69421 ctgagtttcg atatatggac aagtccgtct tgcttcacac cgatatcaac aaatgcgccg
    69481 aagtcaatga cattacggac cgttccagtc aattccatcc ctggtttcaa gtcttccata
    69541 ctcaatacat ctgtacgtaa taagggcgct ggcatctcat cacgcatatc tcgtccaggt
    69601 tgtgtcagcc cagctaaaat atcggctaac gtttcttctc cgactgatag gctttcagcc
    69661 agtttctcta cggataatcg tgtcaatttt tctactgctt cttctgtacc aagctctttt
    69721 tctgaaagtt ggactgaagt taatatttct tttgcaatag aataactttc gggatggata
    69781 cctgtgttgt ccaaaatgtt tttcccacca gggactcgca agaatccgat tgcttgttca
    69841 tatgcttttg gtcctaagcg tggcactttt ttcaattgag ttcgtgcggt gaattctccg
    69901 ttttcttcac gataaatgac aatgttttgg gcagttgttt tattcaatcc tgatatatgc
    69961 tgcaagagct gcgggcttgc tgtattcaca tccacaccta cttggttaac cgctgtttcc
    70021 acaacaaaat ccaattgttc agccaaacgt ttttgagaaa cgtcatgttg gtactggcct
    70081 actccgacag ctttaggatc gattttgact aattcagcta aaggatcttg caggcgacgg
    70141 gcaatagaaa cagcacttct ttcttcaact tgtagatgcg gaaattcttt tcgtgcaatt
    70201 tcgctagcgg agtaaacaga agcgcctgct tcgttgacga tagcgtaata ggttttatgg
    70261 tcggcggatt tcaactgctc agccacaaaa agttcagatt cccgactggc tgtaccattt
    70321 ccgatagcta ccatatctac ttgatattta ttaattaatt ggataaaagc tggtccagca
    70381 gcttctcttt ttgcttgcgc tgcaggttta tgaggataaa taacttcgat tgctaaaact
    70441 ttccctgtcg catctacgac tgctagttta catccagtac gataagccgg atcaaatccc
    70501 aggacaactt taccttttag tggcggttgc aacaaaagat tacggaggtt ttcgccgaaa
    70561 atagcgattg cttgctcatc tgccttttca gtcaattcat tgcgcagttc tcgctcgatt
    70621 gctggctgaa taaagcgttt ataactatcc tgataggctt ctctgacgaa tgaagaagaa
    70681 ggagaggcag gatttttgac tatttggcga tccaagtaag ctaaaattgc tgcttcatct
    70741 acttgaaaga atactttcag aatatcttct ttttctccac gattagtagc taatattcga
    70801 tgagaaacca ttttatggac gggttctgca aagtcataat acatttcata tacgcctttt
    70861 tcatctgctt gctcatcctt gacattgctg acatacatac ctttgttata cgtataagac
    70921 cgaatccaag tccgaaattt tgcattatcg ctgacttgtt cagcaataat ctcatgagca
    70981 ccgtgcaacg cttcttcggc agaagagact tctttttctt tgtcaatata tttttctgct
    71041 tcagattgca cctctccatc tgtaagctgc atcagccact tcgcgagtgg ttcaagtcct
    71101 ttttctttag caatcgttgc ttttgtccgt cgtttttgtt tgtatggacg atacaaatct
    71161 tccacttgtt gcattttcac ggcttgggtg atttctgctt ctaactcggg agtcagtttc
    71221 ccttgttcat cgattagccg aatcacttca gttttacgtt tttctaagtt ttcaagatag
    71281 gcataccgct cttcgatttc acgaatctgg acttcatcaa gacttccagt catttctttt
    71341 cggtaacgcg cgataaaagg aacagtgttt ccttcattta acaaattaag tacagtagtc
    71401 aactgcttag gacgatagtc tgaaagttct ttttgtacaa gctgaatgat cgtctggttc
    71461 aaattttccg tcattaaaat gcctcttttc tgctaaaaat tgcttcttta ttctatcata
    71521 ctttttatcc tgggttaaac tactgaaaga aacaatattc tctataaaaa taaaaagagc
    71581 cgcaacaaag tcacagctcc ttcattcttt ccattagtca gattccatgc caaggtcctt
    71641 cgttgttctg atattcaata tcttgaagaa taccttcctt gtcaaaaaca accccatgca
    71701 atgaccctcc gaatacagcc ccaccgtcca ttccgatttt atgatcctga atccagaggt
    71761 ctgttgtctg catatctcca tggagcattg gtgtaatcgt atgtccaaat acaattgtct
    71821 tacctgtatt gtttttccct tcatgaaatg gttcccttat ccaaataaag tctcttagac
    71881 ttgtcttacg ccagtctttc tttgtcaaat ccacaccggc atggacaaaa agataatttt
    71941 cccattcata atacaagggg cgctggacta aaaatttaat cagttctgaa tatctcgatt
    72001 ggatcatcat cgagatttca gttggggagt attcctccga tgcccctggg tgaatcaggc
    72061 tttcaaacgt ttcttttcca ccatttctca tataaggcgc ataccagtcc tccggtgatt
    72121 gcagaaattg caaaaaatat tcttcatggt ttccccggag gtaaatggct cctgtttctt
    72181 cgactaattg ctttcctaat aaaaaacatt cttttgtacg aggacctcga tcattgagat
    72241 cccctaataa aacaagctga tggatctttg gatcataata gtgaataagt ttttcaaaaa
    72301 gctcatgttt gccatggaca tccccaatag cataaatcaa tgatttcatg tggatcacca
    72361 tcctcaacgc tagtatagcg catattggaa atggtcgaca atcaaaacta ttgttttcta
    72421 tttaattaaa gctgtaaacc gcagttctgc ttcttctgga gagattccat ggtcttgaac
    72481 atagcgattg cgcggatgtt tcgcacactc tatgctacat gctcctaaat gtttttcttc
    72541 attttcaatg gaagcaagaa tctgacgatt gcactcagga ttgctacaat tgatatatcg
    72601 ttcacatggt gttccgtcaa accagtcgcg accgacgatt tgtttatcta cttggttgat
    72661 atcgacagcg atccgttcat caaacacata catcttgccg tcccataatt ctccttggac
    72721 ttcaggatcc ttaccataag tagcaatacc gccatgcagc tgtccgacat ctttgaatcc
    72781 ttcacggaca agccaaccag aaaacttctc gcaacgaatg ccaccagtac agtaggtcac
    72841 tacccgtttt tccataaatt cttctttgtg ctcgcggatc cagtctggaa gctctcgaaa
    72901 actgcgtata tctgggcgta cagcccctcg aaaatgtccc aagtcatatt cataatcatt
    72961 ccgtgcatca atcaccactg tctgttcatc taaaatagct tctttaaatt cttgcggtga
    73021 aagataggca cctgtcactt ggtttggatc aatgtcctct tctagcttta aacttacaag
    73081 ctctggacgg tatcttacaa acatcttctt aaaggcatgt ccttcgcttg gatcgatctt
    73141 gaacatcgta tcagcaaatc gaggatcagc tttcattgct ttcatatagg cagtcgtgtt
    73201 ttcaacggtt ccagacacag taccatttat tccttcttca gctactagaa tacgaccttt
    73261 aagatccaaa gatttgcaaa aggctaaatg atttttggca aattcctctg gttcttcgat
    73321 ttttgtataa ttgtaataaa gcagtacttg ataatccatg tatttcttcc ttccttcttt
    73381 tcgttcctaa acagtataaa gaaggcgttc gcatttgacg atttatttgc ttgtgtataa
    73441 ttacgcatgg aaagtttttt gtttacataa tattattatt tgaattaaaa agacttcgct
    73501 ttcctgtttc gcacagaa
//
LOCUS       DASHWW010000008        66048 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.008, whole genome shotgun sequence.
ACCESSION   DASHWW010000008 DASHWW010000000
VERSION     DASHWW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 66048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.008"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(27..725)
                     /locus_tag="U2R64_000636"
     CDS             complement(27..725)
                     /locus_tag="U2R64_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEM8917480.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(718..2070)
                     /locus_tag="U2R64_000637"
     CDS             complement(718..2070)
                     /locus_tag="U2R64_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEM8917481.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2293..3693)
                     /locus_tag="U2R64_000638"
     CDS             complement(2293..3693)
                     /locus_tag="U2R64_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEM8917482.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3854..4591
                     /locus_tag="U2R64_000639"
     CDS             3854..4591
                     /locus_tag="U2R64_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEM8917483.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4716..5195
                     /locus_tag="U2R64_000640"
     CDS             4716..5195
                     /locus_tag="U2R64_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HEM8917484.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5192..5959
                     /locus_tag="U2R64_000641"
     CDS             5192..5959
                     /locus_tag="U2R64_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917485.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6189..6758
                     /gene="lepB"
                     /locus_tag="U2R64_000642"
     CDS             6189..6758
                     /gene="lepB"
                     /locus_tag="U2R64_000642"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEM8917486.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6862..7464)
                     /locus_tag="U2R64_000643"
     CDS             complement(6862..7464)
                     /locus_tag="U2R64_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8917487.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7570..8039
                     /locus_tag="U2R64_000644"
                     /pseudo
     CDS             7570..8039
                     /locus_tag="U2R64_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8145..8729
                     /locus_tag="U2R64_000645"
     CDS             8145..8729
                     /locus_tag="U2R64_000645"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEM8917488.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8732..9805
                     /gene="prfA"
                     /locus_tag="U2R64_000646"
     CDS             8732..9805
                     /gene="prfA"
                     /locus_tag="U2R64_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEM8917489.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9798..10637
                     /gene="prmC"
                     /locus_tag="U2R64_000647"
     CDS             9798..10637
                     /gene="prmC"
                     /locus_tag="U2R64_000647"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEM8917490.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10630..10809
                     /locus_tag="U2R64_000648"
     CDS             10630..10809
                     /locus_tag="U2R64_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917491.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10831..11856
                     /locus_tag="U2R64_000649"
     CDS             10831..11856
                     /locus_tag="U2R64_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEM8917492.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12031..13275
                     /locus_tag="U2R64_000650"
     CDS             12031..13275
                     /locus_tag="U2R64_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEM8917493.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13428..14375
                     /locus_tag="U2R64_000651"
     CDS             13428..14375
                     /locus_tag="U2R64_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8917494.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14509..15138
                     /gene="upp"
                     /locus_tag="U2R64_000652"
     CDS             14509..15138
                     /gene="upp"
                     /locus_tag="U2R64_000652"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEM8917495.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPGGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15277..15519)
                     /locus_tag="U2R64_000653"
     CDS             complement(15277..15519)
                     /locus_tag="U2R64_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917496.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15640..15712
                     /locus_tag="U2R64_000654"
     tRNA            15640..15712
                     /locus_tag="U2R64_000654"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15673..15675,aa:Thr,seq:cgt)
     gene            complement(15831..16469)
                     /locus_tag="U2R64_000655"
     CDS             complement(15831..16469)
                     /locus_tag="U2R64_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEM8917497.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16592..17224)
                     /locus_tag="U2R64_000656"
     CDS             complement(16592..17224)
                     /locus_tag="U2R64_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEM8917498.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17575..17874
                     /locus_tag="U2R64_000657"
     CDS             17575..17874
                     /locus_tag="U2R64_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8917499.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18369..20534
                     /gene="acm"
                     /locus_tag="U2R64_000658"
     CDS             18369..20534
                     /gene="acm"
                     /locus_tag="U2R64_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HEM8917500.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20806..21291)
                     /locus_tag="U2R64_000659"
     CDS             complement(20806..21291)
                     /locus_tag="U2R64_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEM8917501.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21381..21726
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21771..22412
                     /locus_tag="U2R64_000660"
     CDS             21771..22412
                     /locus_tag="U2R64_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8917502.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22431..23066
                     /locus_tag="U2R64_000661"
     CDS             22431..23066
                     /locus_tag="U2R64_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8917503.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23084..23899
                     /locus_tag="U2R64_000662"
     CDS             23084..23899
                     /locus_tag="U2R64_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917504.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24218..25654
                     /locus_tag="U2R64_000663"
     CDS             24218..25654
                     /locus_tag="U2R64_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8917505.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25843..28290
                     /locus_tag="U2R64_000664"
     CDS             25843..28290
                     /locus_tag="U2R64_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEM8917506.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28520..29587
                     /gene="rlmN"
                     /locus_tag="U2R64_000665"
     CDS             28520..29587
                     /gene="rlmN"
                     /locus_tag="U2R64_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEM8917507.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29780..30883)
                     /locus_tag="U2R64_000666"
     CDS             complement(29780..30883)
                     /locus_tag="U2R64_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8917508.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31436..31984
                     /gene="aac(6')"
                     /locus_tag="U2R64_000667"
     CDS             31436..31984
                     /gene="aac(6')"
                     /locus_tag="U2R64_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEM8917509.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            32530..34191
                     /locus_tag="U2R64_000668"
     CDS             32530..34191
                     /locus_tag="U2R64_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917510.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34261..34608)
                     /locus_tag="U2R64_000669"
     CDS             complement(34261..34608)
                     /locus_tag="U2R64_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HEM8917511.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34692..35633
                     /locus_tag="U2R64_000670"
     CDS             34692..35633
                     /locus_tag="U2R64_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917512.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35634..36677
                     /locus_tag="U2R64_000671"
     CDS             35634..36677
                     /locus_tag="U2R64_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917513.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36683..37753
                     /locus_tag="U2R64_000672"
     CDS             36683..37753
                     /locus_tag="U2R64_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917514.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37743..38696
                     /locus_tag="U2R64_000673"
     CDS             37743..38696
                     /locus_tag="U2R64_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8917515.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38708..39718
                     /locus_tag="U2R64_000674"
     CDS             38708..39718
                     /locus_tag="U2R64_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8917516.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(40003..40824)
                     /locus_tag="U2R64_000675"
     CDS             complement(40003..40824)
                     /locus_tag="U2R64_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEM8917517.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(40921..41199)
                     /locus_tag="U2R64_000676"
     CDS             complement(40921..41199)
                     /locus_tag="U2R64_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917518.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            41467..43476
                     /gene="metG"
                     /locus_tag="U2R64_000677"
     CDS             41467..43476
                     /gene="metG"
                     /locus_tag="U2R64_000677"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEM8917519.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(43955..44542)
                     /locus_tag="U2R64_000678"
     CDS             complement(43955..44542)
                     /locus_tag="U2R64_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917520.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            44717..46039
                     /locus_tag="U2R64_000679"
     CDS             44717..46039
                     /locus_tag="U2R64_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8917521.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            46194..46970
                     /locus_tag="U2R64_000680"
     CDS             46194..46970
                     /locus_tag="U2R64_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEM8917522.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            46963..47532
                     /gene="rnmV"
                     /locus_tag="U2R64_000681"
     CDS             46963..47532
                     /gene="rnmV"
                     /locus_tag="U2R64_000681"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEM8917523.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            47525..48409
                     /gene="rsmA"
                     /locus_tag="U2R64_000682"
     CDS             47525..48409
                     /gene="rsmA"
                     /locus_tag="U2R64_000682"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEM8917524.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            48860..49489
                     /locus_tag="U2R64_000683"
     CDS             48860..49489
                     /locus_tag="U2R64_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917525.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(49613..50722)
                     /gene="ugpC"
                     /locus_tag="U2R64_000684"
     CDS             complement(49613..50722)
                     /gene="ugpC"
                     /locus_tag="U2R64_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEM8917526.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            50931..51353
                     /gene="mgsA"
                     /locus_tag="U2R64_000685"
     CDS             50931..51353
                     /gene="mgsA"
                     /locus_tag="U2R64_000685"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HEM8917527.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            51676..52212
                     /locus_tag="U2R64_000686"
     CDS             51676..52212
                     /locus_tag="U2R64_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEM8917528.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(52252..54015)
                     /locus_tag="U2R64_000687"
     CDS             complement(52252..54015)
                     /locus_tag="U2R64_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917529.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(54018..55733)
                     /locus_tag="U2R64_000688"
     CDS             complement(54018..55733)
                     /locus_tag="U2R64_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917530.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLVTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(56512..56736)
                     /locus_tag="U2R64_000689"
     CDS             complement(56512..56736)
                     /locus_tag="U2R64_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917531.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            56927..59704
                     /locus_tag="U2R64_000690"
     CDS             56927..59704
                     /locus_tag="U2R64_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8917532.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            59785..60204
                     /locus_tag="U2R64_000691"
     CDS             59785..60204
                     /locus_tag="U2R64_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEM8917533.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            60216..60686
                     /locus_tag="U2R64_000692"
     CDS             60216..60686
                     /locus_tag="U2R64_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8917534.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            60703..61482
                     /locus_tag="U2R64_000693"
     CDS             60703..61482
                     /locus_tag="U2R64_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8917535.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            61469..62290
                     /locus_tag="U2R64_000694"
     CDS             61469..62290
                     /locus_tag="U2R64_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8917536.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            62307..63356
                     /locus_tag="U2R64_000695"
     CDS             62307..63356
                     /locus_tag="U2R64_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8917537.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYIQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            63369..64373
                     /locus_tag="U2R64_000696"
     CDS             63369..64373
                     /locus_tag="U2R64_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8917538.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            65006..66025
                     /locus_tag="U2R64_000697"
     CDS             65006..66025
                     /locus_tag="U2R64_000697"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEM8917539.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        22105 a        11477 c        13456 g        19010 t
ORIGIN      
        1 ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata gggcagatcc
       61 aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc caggttctca
      121 tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta aatgacacct
      181 tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa aggtcgttca
      241 ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt ttcattgaat
      301 tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact taacgtgtag
      361 tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta gtagtgacct
      421 agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat atagttgatc
      481 aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa gtcttgacca
      541 ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat actaacgatc
      601 tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa aaggtttccg
      661 ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag ttcataatta
      721 gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac gaagctgcaa
      781 tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt tgattttttc
      841 gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc cggcaacttt
      901 tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg ggatatccat
      961 atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc cgtctgcgta
     1021 attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa tcatatcgat
     1081 tacttgattg atacctacag gatttttgac aagtactaat gtacattttt tcccattgat
     1141 attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt gtttgatttt
     1201 atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat tgtagacatt
     1261 atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat ctgctgacac
     1321 attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt tgaagtcaca
     1381 atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat gcaagatgtg
     1441 atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt cacgatcttc
     1501 ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat tgaagattgg
     1561 tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt ctacaatcat
     1621 tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa tatttgtaaa
     1681 taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt catctatttc
     1741 taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag tcgatacaat
     1801 tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt gctggcgcaa
     1861 aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga caacgacgac
     1921 ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg ctagtttacc
     1981 tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg tttttccaac
     2041 tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga tttgctgacg
     2101 aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt ttcttattct
     2161 taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga tttaacaaaa
     2221 aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt ccctcttacc
     2281 tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc ctagatctcg
     2341 tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc caataaacat
     2401 cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc ctaaagataa
     2461 accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg tttgttcttc
     2521 tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca taaagacaac
     2581 gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga tgttatcttc
     2641 acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg ttcgaatccc
     2701 gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa tgatcagtgt
     2761 tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag tcgtaatcga
     2821 ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata aatggtcctt
     2881 ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag ctaacacagc
     2941 taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt tgtataatag
     3001 ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa tcaaaaacat
     3061 gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc cagtgacgtc
     3121 aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa cggcatcacg
     3181 ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc caaaaagtaa
     3241 ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac cagacaaacg
     3301 cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc gtcgtttaga
     3361 aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt gaaataatat
     3421 ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag tcgatagtcc
     3481 agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa catggctatc
     3541 tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca tcaatatata
     3601 ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct gtcctcgccg
     3661 ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac aatagtcgtt
     3721 tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca gataacaata
     3781 cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa aaagaaggag
     3841 gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa atcaaaaaat
     3901 aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag aagtaaagcc
     3961 taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg aattcatgtc
     4021 tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta aaagtgagta
     4081 tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga aaactgacca
     4141 tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa tggttttaac
     4201 aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct tcaatatgcg
     4261 attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg gaagtgccct
     4321 gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg atatccaaaa
     4381 gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct atgaacgctc
     4441 tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt gcgtgttcgc
     4501 tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag cttacttaaa
     4561 aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac gtaagaaaaa
     4621 aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag taaagtaagg
     4681 aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca cctattttga
     4741 agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt attgtgaata
     4801 gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca acaccaacta
     4861 cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc actacgacaa
     4921 gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca actgacagct
     4981 caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc aatccaagta
     5041 caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact gtagatgata
     5101 acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca ggaaataccc
     5161 aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc ttatcaacgg
     5221 ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc gtggatatac
     5281 gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac tttggcaaaa
     5341 ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg tttattttac
     5401 tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg tcactcagct
     5461 ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat cgatagataa
     5521 tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg acgaagatta
     5581 tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga tcaaaacaaa
     5641 tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc cttattacta
     5701 tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct actcggacat
     5761 ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac ctgtcggatt
     5821 gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc cttatcgtct
     5881 gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata gtcgtagcca
     5941 aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg ataaaaacgt
     6001 ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt atataacgag
     6061 aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt gtagaataaa
     6121 gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat acaagtagga
     6181 ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta ttagcggcta
     6241 ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat tcgatggacc
     6301 ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat gaacgaatgg
     6361 atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa cggatcatcg
     6421 gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat ggcaaaaagt
     6481 atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag ttacaaggag
     6541 aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc tttacgagtg
     6601 actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac cgcttgattt
     6661 caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga aaagttgttt
     6721 tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa aagaagctgt
     6781 gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct tggagttgct
     6841 cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa gcgaagcgtt
     6901 tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag agacaaagcc
     6961 cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga ctttcggatg
     7021 actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag gagctaaaat
     7081 ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta caagtgatag
     7141 aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt ggatcgttcg
     7201 gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca tagtttctga
     7261 agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa caagcccagt
     7321 tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat aagtagttag
     7381 ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat ggttagcgat
     7441 ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg aaattttaac
     7501 ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa gggagaatct
     7561 agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa gtgtgtccga
     7621 gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga aaaatatatc
     7681 gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata tttaggcttt
     7741 atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt atgggaataa
     7801 aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca gaaggttacg
     7861 cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac tactctatat
     7921 atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa gtttttccaa
     7981 atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa caaaagtgag
     8041 caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa atgctgaaaa
     8101 tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca caactatttt
     8161 ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc gcacataatt
     8221 atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca agagatggtt
     8281 taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata tttgaagaaa
     8341 cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg ctgatcgatg
     8401 aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg gacgaattgg
     8461 atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta tttgaaggat
     8521 caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc tgttggttct
     8581 gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt tatgaaggcg
     8641 atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa cattactttc
     8701 acccatcaat gattacagaa ggagaataag catgtacgat caattacaag caattgaaga
     8761 ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg atacaaagcg
     8821 ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag tttatcgtcg
     8881 ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg aaaaactgga
     8941 tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag aaaaagaagt
     9001 cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg ataaaaatat
     9061 catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg ctggcgatct
     9121 tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag tgatggaagc
     9181 taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg gagacaacgt
     9241 atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc cttcaactga
     9301 atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag aagctgaaga
     9361 agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg cttcaggtgc
     9421 tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact taccaacagg
     9481 gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa aagcaatgaa
     9541 aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg agtatgatgc
     9601 caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga cgtataattt
     9661 cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat tagatcagat
     9721 tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc aaacatcaaa
     9781 actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca cgggcttctt
     9841 cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt ttggaacgaa
     9901 aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca gaagaagaac
     9961 agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct cagtatttgc
    10021 taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca ctgatccctc
    10081 gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt gtaccgttag
    10141 aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa gcagcaagaa
    10201 aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta gcgaaagaaa
    10261 atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta ggaccagtaa
    10321 tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg aatgaatggg
    10381 aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt gctgagaacg
    10441 atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta aaatcaaatg
    10501 gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa atatttcagc
    10561 aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat gaacgaatga
    10621 tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt tattataaaa
    10681 aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt ttatccacta
    10741 ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag acaaaataag
    10801 aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga tgaaacagaa
    10861 ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc taccgaaaca
    10921 gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt gttttctgta
    10981 aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga acaagtaaaa
    11041 gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt ctggcctgga
    11101 ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt gacgggagga
    11161 ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt aatcgaactt
    11221 tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag tccaacgact
    11281 gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga tgatggagct
    11341 acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc catgcctatg
    11401 attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga atctcctgtt
    11461 gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg gatgaaatac
    11521 aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg gtcaactgca
    11581 gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc cgaaattgcg
    11641 gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc agtagaagcg
    11701 gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact tggattagat
    11761 ttgatttttg tacaagtgta tccagaaact ggattgggca atgcttacat gaatcgcttg
    11821 aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg tcgcattctt
    11881 ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa ctaagcgtaa
    11941 ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg aaaaataaaa
    12001 ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt tgaccctgat
    12061 ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga gctgattgcc
    12121 tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt gacaaataaa
    12181 tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt cgatatcgtt
    12241 gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc gaacgtccag
    12301 cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga accaggggac
    12361 acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc accagtcaac
    12421 ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac agaagttatt
    12481 gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat cgtagcaggt
    12541 gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc agatgaagta
    12601 ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc aggacttcat
    12661 cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac attgcgtggc
    12721 cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat aaatagtgcg
    12781 gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa agcagtagca
    12841 ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat cgccaatgca
    12901 aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc aggggcgaca
    12961 gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa agaagcagag
    13021 agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt tgaaacacta
    13081 agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac tcgcgggttc
    13141 aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca agcaaaagat
    13201 gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga aaaatttccg
    13261 ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa tgttgggctt
    13321 ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct ctctagtata
    13381 tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg actgatcgta
    13441 tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat ccgcgtatct
    13501 atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa tcacctgtga
    13561 acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg ggaaaactca
    13621 atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt ttttatattc
    13681 atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc agagaacttg
    13741 cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca gaagcaaaat
    13801 atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa ttagccaagt
    13861 caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt ggtaacatgg
    13921 ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc aagcaattgc
    13981 tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa ttcggagaaa
    14041 actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg acgaatgaag
    14101 aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa ctaaatgatc
    14161 ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa ggtgaggctt
    14221 atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc caaggaatca
    14281 tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt gcagcaatgg
    14341 cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc aggaaaactt
    14401 cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa tcacttgatt
    14461 ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat gggcaaattt
    14521 caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga caaaaactgc
    14581 ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc atatgaagta
    14641 tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga aacaacacaa
    14701 aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg tattggaatg
    14761 gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg tctttatcga
    14821 gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga cattgatgca
    14881 cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat catggcaatc
    14941 gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt agcagcacct
    15001 gggggagtaa aagctttgca agaagcgcat cctgatattg acatctatac agcttctcta
    15061 gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc gggtgaccgt
    15121 ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt gtcacatcct
    15181 tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc gtttgcatat
    15241 aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atctttttta gttctttgta
    15301 gttaacgatt actacaccct tactttgcgt catcaagttc gcattttctg cagtttcatc
    15361 aatctcaaca acagcggaat ttttcaattg ctttgaaatc gttccagttt gcgacttgcc
    15421 gtgaattgtg aacattacgt gagtattgat cttgaatttt tcaccaattt ccgatggtac
    15481 gatagttgta tcaaattttc caaaagttgc cattttcata aaacctgcct ttcacatcaa
    15541 ttataccacg ttttatgaaa aatatcatga aattaaacta attttccatc ggactcttta
    15601 caatcagcca aatagagtat ataatttctt ttggataagg ccagcttagc tcagttggta
    15661 gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg cattaaaaga
    15721 gaagacagat atatcaagga tttttaatcc attgatacat ctgtcttttt gtttaaagga
    15781 aataaagtat gctttcttag caatagagca tgtattattt ctataaaaat ttaggagaat
    15841 aaaacgacta gcaatatagc tgtgaaatca aatatcacat gaactgccca acttgtaatg
    15901 atcgagttgc ttttaatggc agcttggttg aataacaatc ttgccacccc ttgtatcaaa
    15961 aggatgtgtg ctacagtgtg taaaatattt ccattatcat aagtactgta atggataaat
    16021 ccaaagatga ttgctgacaa gaaactagcg acaggaatgc tgaacttact agaaaaaata
    16081 gcgagaaaat acactgagaa caattcttct ccaagtatca tgataggcaa aataataaat
    16141 aataacgggc tgaaagcctc atttattgga ttgcctgtta aaccccattt caaaatttgt
    16201 tgcaaaaata ccgagactgc ggcactgatt actacattga taaaaaaata tttggctata
    16261 tttttgacag gagcgacagg tttcgagaac atttttttcg tatctttttt accaaaaaca
    16321 agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa tgctaataat ggatggcgca
    16381 aatagcaacc ctaacaaacc gagtacaacg acaatagtgc ccaatatccc ttttttaagt
    16441 tctatttttt ttcctaaaat gttattcatg ataataactc ctactattca gtttttgaag
    16501 atagagtcag tatacatgaa gagttaaaat aggcaatgtt tttttatgga tatttgtatt
    16561 gctaaaaatt tatcttatat attcattttg attatactac ttttatttgt aaaaattttc
    16621 tagcaaaacc aagtgcttgc aactgattaa gcgtacaatt ttttagatgt tccgagcgta
    16681 cttcaatcat ttcaaaggag ttgctactta aatcgatatt ttttaaatca gtatcaaaaa
    16741 agctagcatt ttctaaatca ttagtagaaa acattatttt agtgagggaa cagtctacaa
    16801 aatctgcgct tgataagaca gagtgctcaa aggtactttc ttttatgttt gaaccagata
    16861 aatttacata gtccatttta caattctcga ataacgtgtt cccaatataa ctttccatca
    16921 atttagtacc tgttaattta caattgacaa atttcacgcg atgcaacatg ctttttgtca
    16981 atatacagcc tgaaaaatca cagttttcga atatacagtc ggtaatctcc attctttgaa
    17041 aatcattgga agcaaaaaat gcatacttga aaatagattt gtaaataatt ggatggcaga
    17101 ttatttggtt ttcgatgacc tctttttgtg aaaggatatt atacagttca aaatcttcgt
    17161 tttcatagat atgaaaaaag gatcctttat tcaagcttgc ttcattaact ttaggaaaaa
    17221 tcatatttaa ttacctccat tttcataaag tcatattaac aaaagctaaa ccaacttaca
    17281 ttagcagaaa atgagatagg ttttcgcctt tttcgataac gatagtgtcg ctatctcttg
    17341 aaacgttctt agaattgccc tgagagacac aaattaggcg taattctaat aaaaatctta
    17401 gaataaaaat ttttactgat ttaatttaga atgtttttaa aataaaaatc gttgccataa
    17461 cagtgtattg aaaggtttta acaatccagt aatgatttaa aaaaatctag atgtagcgta
    17521 tactttgttt atagaatgta gtgggaagaa atatattttt gggaggaaat cgtgatgtct
    17581 aaaagtgaag aaatagaaaa catggtacta aaattatatg atctcgtttt aaatccagag
    17641 atcaaagaaa aggaacgtat acttttgata gacgcaaaga caggcttaga aaaaggtcag
    17701 tattatccta aagtcataaa taatttggaa cgtagtttac gtccgttagc aatcagggga
    17761 gaattgtcta aaccagtatc accgttttat atggagatat caacaatagg aaaatttgaa
    17821 aaagaattag gtcgaggaat ggcttcggca ccgattactt ttgggcattt ataaaaacga
    17881 gttattcatc tcaatgaatt aaaaagtata gtcaatctca taatgcaggc taggttcatt
    17941 tatttgaaca gagtctgtat ttttttattc taaataaaga aacagatgtt tctttatatt
    18001 gtattttatc ctttaattaa cacaaaaaca gctagtataa actaataatg ttaattaaaa
    18061 gtgtatttta tgaaactatc gttatttatt aatgttgcat ttttgtaagt taaaaattgg
    18121 aaatatagat tgaaaaaaag aaagcaataa gtaaaataaa atgaatatat gcgaaaaaat
    18181 aatttacatt aggaaaaacc ttgtaaaaac agttttttgg catatttatt ttttataaat
    18241 atttgtaaaa taactatcaa ttttttagtt aaaagattgg aaatgagtgg gggaggaatt
    18301 gaagaaagga tttttgagag atgatatagt aggttttatt tttagttaaa ataggggaga
    18361 tagaaaaaat gaaaaagtgt agaaatatta ttttatcaat gttatttatt attactaata
    18421 taacatcact gattcctgtt catgtctatg cggatgcagg cagagatatc agcagtaatg
    18481 tcacttcgtt gaccgtggac ccaacgaata ttacagatgg aggaaacata aaagtaaaat
    18541 tctcgtttga cgaaaaaaaa caaaatatcc aaccaggtga ttatctttgg atcaattggc
    18601 caagtgaagg aaatattcgc ggtgaaggat tccaaaaaga aatcccatta atgattgaaa
    18661 ataaaaatgt tggaacttta acggtcagaa aagattctgc gcaggttgtg tttaatgaaa
    18721 atattaaaaa cctagactca gtagaaggtt gggggcaatt tgagatacag gccagaaacg
    18781 taaccgatac cggtgaagaa aatacgggac cattcaccgt gacgagcggt gataaaacag
    18841 ctactgtaaa tgtgacaaag ccagcttctg gttcttcttc tagcgttttt tattataaaa
    18901 caggagacat gctacctgaa gatactaagc acattcgatg gtttttgaat attaacaata
    18961 acggcactta tgttgaacaa ccagttaaaa tcagtgatga aatccaaagt ggacaaagat
    19021 tagatccaag tacgtttgaa attaatcaaa tacacttagg tgaacagaag gtttatagag
    19081 gagaagaggg aatccaacaa tttttacaag atttccccag cgctacattt aatttttcag
    19141 taactgataa ttacattgaa ataactatac caaaaaactt tgtcaatctt aggaaaataa
    19201 tggtgagtta taagacgatc atagaaaacc cagaacaaat aaattttgag aatcattcgg
    19261 aagcttggtt taaagaattt aataaacctg ctgttgatgg agaaagtttc aatcatacag
    19321 ttaaaaatat ttcagcttct ggtggagtca acggtacagt tagaggcgaa ttgaagattt
    19381 tcaaatatat caatgacaca gagattggta tcccaaatgt gactttcgaa ttaagacgag
    19441 cagatgaaca gcctattcaa ggacagtcta gtatcctgtt gacttcgaat gaacagggag
    19501 aagctagtat caaaggcctg caagtaggag actatgttgt aaaagaaaaa gaagcaccca
    19561 attggattga ttttgatcca ctaagttcaa atgaactcaa attctccata aacgaaaatg
    19621 atacagaggg agtcagttta cctatttata acaagaaaaa ggttacgaac atcacagcaa
    19681 ctaaaatttg gaacggtgga accactccaa gaccgagtat ttattttaaa ttattcagag
    19741 caagtacaaa caattgggaa ccagttcctg atgcagaaac aaaacgatta gacaatggaa
    19801 taacttcagt gacttgggaa gatatccaac agtatgatga tagtggaaac gaatatacgt
    19861 ttaaagtgca agaagtagat caaaacggaa atgattatgt cccttcaggt tatcaaaaaa
    19921 ttgaaaacgg gctagtcgtt acaaatgaga ataaagaagt catttcagtc tcaggacaaa
    19981 aaacatggga agacaatgag aaccaagacg gcaaacgacc gacgacgatc acagtaaatc
    20041 tattagccga cggtcaaccg atccaacaca aagaagtaag tgaaaaagat gattggcgct
    20101 atcgtttcac aaatctgcca aaatacagag acgggcaaga aatcatctat actgtaacgg
    20161 aagacaacgt gcccgaatac agtacgacga ttgacgggta taacatcaaa aacagttata
    20221 caccggaaaa aacaaatata tctataccag gtagccatat aacaccgtgg aaaaattttc
    20281 cagagaagac agagagagag aaaattagaa atctattctc tcaaaaattg caaatatttg
    20341 ctcatacagg agaatccagc gaacaaagaa gcaattatat tagtaagaga gctgtaccta
    20401 aacagataac aaataaatca aaaagcattc ttcctaaaac aagtagtaaa aaatctagtt
    20461 ttgctgtaat cattggttta ttgatagtaa ctatctgtgc tgggatattc ttacaaaaat
    20521 ataaaaaagt ttagttagaa tataatattt tttgttaaat atgactgaaa tcaaaagaat
    20581 aaaattccga tttataatcg aaaaaagaag catttttata tatgcttctt ttttcgtaga
    20641 atcaataaat atggatttgg ctaactatgg aagaatactc gtattagttt tcagcgttca
    20701 tactagttgt tacattgttt gattggccaa aagaatttct gatatatttt gtgctaaata
    20761 aagaaaaaga cgcttgaatt gggaaataag aaaactactc tatcattaca aattttcata
    20821 aactggcaga tgttctaagt aaacaagtat cttttcaaag tcggaaaaat ccataatcaa
    20881 cgtagtggta ttgatatttg gatgaaagcc tacggtatct tgacgatcaa tagcagcatc
    20941 gatcacgact tggatttttt tctctttgtc gtgcatcaat gctaatggag tcactgtacc
    21001 tgctggaacg cctaggaggt caggaagctg ttcttcagaa acaaaagata agcgcttttc
    21061 ttttaattgt tcagctagtt gttttaaatc ggcgtgcttt tcatcaggca agatgacaag
    21121 atagatttgt tttccttttc ttgatttcaa taatagattt tttacttgcg gaccaggtag
    21181 ggaaaaaggg acatttttga ctgacgtaat cgcaggatga tcgacttttt gaaaagagat
    21241 acccagtttt tttagtagtt cataagcttc ttgttcggtt gcacgactca tcgcgcatca
    21301 ccctcctttt tttattagtg tatcataaaa aagagttgac aaatgaaaaa taatcatgta
    21361 aattacacgt aaagttaaaa caaatgacat cgaaaagaag agtagccgtt aggtgttttt
    21421 agagagtctc tggttggtgg aaagaggcag cagttaaccg tgaaacacat cttggagtcg
    21481 attttctgaa gcgtatagta ggaaaatccg gggagcccgt tacagctgcg gtcgttgcta
    21541 gatgaccaga taaggctggc ttttccgtga ggagtcggta aaaaaaggtg gaaccacgtg
    21601 attaacgtcc tttgatcttc ggatcaaagg actttttgtt ttcatctgaa cggcaacgac
    21661 tgtgtgaggt tttttctgca aggaaaaaat aaacagaggt ggaaccacgt ataatacgtc
    21721 ctcttggcat ttgccaagag gattttttta ttttaaagga ggaaaagaag atggagtatt
    21781 tgattgaagt tatgccgcaa ttattagtag gagcactcac aacattgaaa ttatttttat
    21841 ttaccttgat tggctcatta ccattaggga ttgttttagc attaggattg tctttgcatt
    21901 ttaagccgct acgctacttg cttcaaacat atgtatgggt tatgcgggga acaccgctgt
    21961 tgttgcaact gatttttatt ttttatgggt tgccgacgat tgggatcgtt tttgatcgtt
    22021 tcgaagcagc actcattgcc tttatcttaa actatgcagc ttattttgca gagatctttc
    22081 gtggagggat acaatcgatt cctcaaggtc aatatgaagc agcgcaagtt ttgcaattaa
    22141 gtccctttca aacggtgacg aaaatcgtca tcccacaagt gacaaagatt gttttacctt
    22201 ctgtagggaa tgaagttatc aacttggtca aagattcttc cttgatctat atattaggtt
    22261 taggtgacgt aatgcgtgct gggaaaatcg cgatggaacg cgacgcgact ttactgcctt
    22321 tgctaggcgt ggcaatcatc tatcttacat tgactggtat tctaacaatc ataatgaaac
    22381 aagttgaagg aaaattaaat tattaccgct aactgatagg aggaagaaat atgattgaat
    22441 tgaagaaagt gaacaaagca tttggtgaaa aaaaaataat caaagatttg aatctaatca
    22501 ttccagatgg gaaaacatta gctatcgtag gtccttccgg tggcggtaaa accacgcttt
    22561 tacgtatctt ggctggctta gaaagttctg acagcggaga attttattta gacggtgtac
    22621 cgttcaaccc attcgagctt aaaatgaaag aacaagttgt aggagtcgta ttccaagact
    22681 tccagctatt tccacatctg aatatttttg aaaacattac cttagcacca aaaatggtat
    22741 tgaaacagac aaaagaagaa tacaccaaaa aagcagaaga attagcggct tcattaggga
    22801 ttagtgattt attgaatatc tatccttatc agctttctgg cggacaaaaa cagcgggtag
    22861 cgattgccag agcattggct atgaatccac gggtattggc ttatgatgaa ccaacaagtg
    22921 ctttagatcc tgaattacgc cagcaagtcg agcgtttgat cctatcattg aaagaagatg
    22981 gggtaaccca aattattgtc acccatgatt tagtatttgc agaaaatgtc ggtgatcaat
    23041 tactaaaagt ttccccaatt cattaagaaa ggagaagata gagatgaaaa aaaccagttt
    23101 tctattcgct ttgatcgcag gtcttcttct ttttgcaggc tgttcgaaca aaaaaacttc
    23161 agcagataat tgggcgacta tcaacgaaga gaaaaaaatc gttataggtt tagacgatac
    23221 atttgttcct atgggattta gagataaaga cgggaagctc acaggatttg atattgattt
    23281 agccaaagca gtctttgaac aatatgggat tacggtagac tttcagccca ttgactggtc
    23341 aatgaaggaa tttgaactga acaatggaac gatcgatttg atatggaacg gctattccaa
    23401 aacgccggca agagaaaaga aagtgcaatt tacaaaacct tatatggaaa acgatcaagt
    23461 gctgatcaca cctaaagaat caggaatcac aaactttgga caaatgaata ataagagatt
    23521 aggtgcgcaa aatgggtcat ctggttatga tgtatttacg aaacaaccag aagtattaaa
    23581 agagatagtc aaaaaccaag atgctgtttt gtatgatagt tttaatgaag cattgatcga
    23641 tctgaaaagc agacgggtcg atggtctgct gatggataaa gtatacgcag actattattt
    23701 gaaacaaaga aacgaactag aagacttcaa cataacaaaa ggttcttatg agagtgagga
    23761 ttttgcagtt ggtgcacgca agtcagatag tacattagtg aaaaaaatca atgaagccct
    23821 agatcaacta gagaaaacag gtgaattcca aaaaatatcc gataaatggt ttggcgaaga
    23881 tgttacgccg agaaattaac aaatagggga ctgtgacaaa agacgtgtca cagtcccttt
    23941 ttccgaataa acagtgttct cctgccaact ccttgtgact cggagctgaa tggcaggctc
    24001 acaacctctt ggtaaacggt gttcaaaagc cagtttttcg gtattaagcc aaatttatgc
    24061 aaaaatgtag aaagccattt tcacaaaatt tttcttacta ctcgaaacta agcgactttt
    24121 tcacaacctc ctttacataa ttttattttg ttgtggaagg ggtttcgtgt tattctaaaa
    24181 gaggaacgat tgaaggttat aggaaaggaa gagatgaatg gaacacaaag aacttacctc
    24241 atttccaaaa gattttctgt ggggctctgc ttctgcagcg tatcaagtag aaggagcttg
    24301 gcaagaagat gggaaaggag aatcagtctg ggatcgattt gtacggatac ctggaaagac
    24361 atttaaagga acgaacggtg atttggcagt agaccactat catcgttata aagaagatat
    24421 tgctttaatg aaagaacaag gtctgaaagc ttaccgcttc tctgtagctt ggacacggat
    24481 ttttcctaat ggacgaggag aagtcaatca agctgggctc gctttttatg agagattgat
    24541 cgacgaattg attgaaaacg atattgaacc tatgttgact ttatatcatt gggatcttcc
    24601 acaagcattg caagatgaat ataatggttg ggaatcacgt cagatcattg aagatttcac
    24661 tcattatgca gaaacattat ttgaggcatt ccgcgggaaa gtccattact ggattagttt
    24721 gaatgaacaa aatatcttca cttcattagg ttatttgtta gcagcacatc cgccaggtgt
    24781 gacagacccg aaacgaatgt atgaagttaa ccatattgct aatttagcaa atgcatctgt
    24841 catcaataaa tttcacgagt tagaaatgcc tggaaaaatc ggaccaagct ttgcgtatac
    24901 gccaaattat ccaattgaca gtaatcctga aaatgttctg gctgctgaaa atgcagaaga
    24961 cctgatggcc aattattgga tggatgtcta tatgtgggga aaatatccga ttgctgccat
    25021 gaggttctta gaagaaaaag gatgggcacc aacgattgaa gctggcgatg cagaattgct
    25081 agaatctgct aaaccagatt ttcttgggat caattactat caaacggcga cgaatgcatt
    25141 caatccatta aacggagttg gtgctggaaa aatgaatacg acaggaaaaa aaggttcatc
    25201 agaagaaact ggagttcctg gaatgtataa aaaagttgag aatccatttg tcgaacgaac
    25261 aaattgggac tgggagattg acccagaagg attaaggatc ggactgcgtc gtatcacaag
    25321 ccgttaccgc atgccggtac tgattacgga aaatggctta ggagagtatg acaagttgac
    25381 agaagataaa caaatccatg acgactatcg aatcaattac ttacaaagcc acgtcaaagc
    25441 catcaaagaa gcaatttcgg atggagcaga agtcctaggc tattgcacct ggtcttatac
    25501 agatttgctt agctggctga acggttatca aaagcgatat ggatttgtat atgttgatca
    25561 agacgaaaca caagaaggat ctttggaacg atataagaaa gacagttatt actggtacca
    25621 aaaactgatt gaagaaaatg gagagaacct ttagttcaca tacttaaaac aagaaggtac
    25681 ggctggatat ggccgtgcct tttcttgata aaatcattta gaaattaaga aaaactgtaa
    25741 aataagctga aaaatgaaag aaagcgtcag ttctttcaaa caaaacttta gttcccttac
    25801 ttttttttgt ataatgaaac ttgatgaaat gagggataat aaatggcaca aaagaaacgg
    25861 cctactaaaa aaaggaaaaa gacgaaaaaa acgaaaaagc aaaaacagca gcaggaacaa
    25921 atgctgacga ttggtgttgg gtttgccttg attttatttg ctgtcttcgg ctttttaaaa
    25981 ttaggttttt taggaatatt gattgcaaac ggctttcgga tcattgcagg aaatacttac
    26041 caaatcctct gtcttttatt agccgtatta ggattttgga ttgtcattaa gaatacagag
    26101 ttttcaattg gtaaaaaccg acgctggttt ggcggcatac tcttttattt cggtatctta
    26161 ttattgttac atgcccattt atttggcaaa ctccatactg gggaaccaaa tatcatgggg
    26221 acgacatggg atttgttagc cagtgatata aaacaaagtc aagtagacaa taacgttggt
    26281 ggtgggatga ttggagcaat cctttatcat tttacttact tcttgattgc acagcctgga
    26341 agttatttag cagcagtgct attactggca ggaggagcat tcctgttcag taatctggaa
    26401 ggctatcagc tgttaaatgg tatccaatca attggagaac gagtacagga attattggaa
    26461 ggtgatcctg ccaagcaagc tcgaaagcaa gcggcaaagg aagagagaat gaaacagcgc
    26521 gcagaagcga aagaagcaag gcgcttagct gcaaaagaag ctgcagaaaa agaagctgca
    26581 gaatatgaga agaaaaaagc ggtgagccag caaagggaaa atactgctga tgaatggcag
    26641 gaaccagaaa atacagagcc ggagcagcta agttttgttc caatcgacag ttttcaagaa
    26701 aatatccatc ctgcgaatct agagaaacca gtaccagata caccaaaaca gaccaataca
    26761 gcagaaggtt tttcagatga gttgccagag gatgacggta cctcattaga atttgagatt
    26821 gaagcagaac aggaaaatca agactatgaa ttaccgacag ttgatttgct tgattctata
    26881 ccaactgtgg atcaaagtga tgagtataaa aaaattgaaa aaaatatcgg cgtattagaa
    26941 caaactttcc aaagtttcgg tgtcgatgcc aaggtcgtca aagccagctt aggaccatcc
    27001 gtcacaaaat tcgaagtcca gccggctgta ggggtaaaag taagtaaaat tgtgaactta
    27061 acagatgata tcgcgcttgc tttagcggcg aaagatgtcc ggatggaagc accgattcca
    27121 ggtaaatcac tgattggtat tgaagtacca aatggaaaga tcagtatggt ttcctttaga
    27181 gaaatcatcg aagcacaacc aaaccaccca gataaattac tagaagtacc tttaggacgt
    27241 gatgtttctg gacgggtaca aacggctgat ctttcgaaga tgcctcactt actcgtggct
    27301 ggttcgactg gtagtgggaa gtcagtagca attaatggga ttatcacaag tatattaatg
    27361 cgtgctaagc cccatgaagt aaaactgatg atgatcgatc cgaaaatggt tgaattgaat
    27421 atgtacaacg gcatacctca tctgttgacg ccggtcgtga cgaaccctag aaaagcagcg
    27481 caagccttac aaaaagtagt acaagaaatg gaagaacgat atgaaaaatt cgcggcaacc
    27541 ggagtaagaa atatttctgg ttacaatgaa tttgttcaac agaaaaactt ggaaaacgga
    27601 acgaaacatc caaccttacc attcatcgta gtgatcgtag atgaattagc tgatttgatg
    27661 atggtagcca gcaatgaagt tgaagatgcg attattcgtt tagcgcaaat ggctcgggca
    27721 gcggggattc atatgatcct agctactcaa cgtccaagtg tggatgttat cacaggaatc
    27781 atcaaagcaa atgtaccttc cagaatggca tttgcggtat caagcggtac agattctcgg
    27841 acgatcattg attctaatgg ggcagaaaag ctcttagggc gaggagatat gctattcttg
    27901 ccaatgggtg agaataaacc gatccgtgtg caaggagcat tcatttctga ccacgaagta
    27961 gaacgggtcg ttcaatttgt tacagatcag caagaagctc attatgaaga gaaaatgatg
    28021 ccgacagatg aagttgaaac gacaggtgct ccagaacagc cacaagatga gctgtttgaa
    28081 gaagcaaaag cacttgtcgt tgaaatgcaa acggcaagta tttcccttct ccaaagaaga
    28141 tttcggatcg gttacaaccg agcagcacgt ttagtagatg aactggaagc tcatggagtt
    28201 gttggcccgt cagaaggaag caagcctcgg aaagtattca ttgagcagga agaaacatca
    28261 gaaacgttgc cggacgataa tgacatgtaa aacttgtgtg atgaagggtt gaaaaacgaa
    28321 taaccaataa aaagacaagg catgatgata ccaaaagaaa aaatggtttt tttccatctt
    28381 ttctaatacg gtatgatgtc ttgtcttttt agtttttgtg agattaaagt tctattcgat
    28441 ttatttgtga agtattgcat taaggaaatg aatcatgtat agtatgtagc gaaactttga
    28501 gaaaaagagg gaaaatactt tggaaaaaca gtccatttat ggcttgacga atgaagaatt
    28561 aatcaattgg tttatagaaa acggcgagaa aaaattccga gctgcccaag tttgggaatg
    28621 gttgtatcaa aaacgtgtaa gtaatttcac agaaatgacg aatctatcga aacaattgat
    28681 cgaaaaatta tcggagcatt ttatcatcaa tcctctaaaa cagatggtcg tccaagaagc
    28741 ttcggatggt acagtaaaat atttgtttga actccctgat aaaaacatga ttgagactgt
    28801 actgatgaga caagaatatg gcttgtcagt ttgtgtgacg acacaagtag gatgtaatat
    28861 cggctgtacg ttttgtgcaa gcgggctgct caaaaagaac cgtgatctga ctgctggaga
    28921 aattgttgca cagatcatga tggtccaaca ttattttgat gagcgcaatc ttggcgaacg
    28981 cgtttcacat gtcgttgtaa tggggatcgg tgagccattt gataattacg acaatgtaat
    29041 ggactttttg catatcatca atgatgccaa aggattggca attggtgctc ggcacattac
    29101 agtttccact agtggattag cacacaaaat caaggaattc gctaataacg gcttgcaagt
    29161 caatctggct atttccttgc acgcgccgaa taatgaggtg cgaacatcga tcatgcggat
    29221 caaccgaagt ttcccaattg agaaattgat ggaagctgtg gatgagtatt tagagaaaac
    29281 aaaccgtcga atcacgtttg aatatatcat gttgaatcaa gtaaatgata gaccagagca
    29341 tgcgcaacaa ttagcagatc tattaaaaga taagaaaaaa ttagcatatg tcaacttgat
    29401 tccatataat ccagtcagtg aacatgatca atattctcgc agtccaaaag ctgatgtatt
    29461 gagattttat gatgtattga agaaaaacgg cgtaaactgt gtgatacgta aagaacatgg
    29521 tacagatatt gatgcagctt gcggacaatt gcgaagcaag caaatgaaaa aaacagttgc
    29581 caaataatcg tatcctactc gttttttcaa ttaccataaa aggagcagtt ttcttaatta
    29641 aggaactgtt caacttaaat aagagaaaag attctatagc gaaagctata aagctttttt
    29701 tgacaagaaa aaccctcatc aagcaaagaa atgtcctcaa tttgatgaca gcctgcttga
    29761 tgggggtttt agcaattatt taactgattt tcttatatcc ttgctggctt tcttgtgtag
    29821 catgataagt ttctacgtca agaatggcct gtttaaattt ttctcgggtg atttcataag
    29881 gcacatgttt aatatcattt gttgccatgg ctttatctaa gattgcttct aaatcggtcg
    29941 tgacattgag attcatgtcg gttaacgata ctggaagttg gttctttttc ataaacacat
    30001 agattttatc aaacaaatcg aactgctgat ccatcatcaa taaggtcagt acaccataac
    30061 tgacagatgc tccgtgaagg tatccctcca ttttttctag aacagtcgta ccgtaataga
    30121 atgagtgtgc catagcagaa ttatagttat tgttaactaa aacagaaacc aatccggtag
    30181 taacaatgat atccgaaacg acttgttcaa ttgcatatga gggacgatcg tcggcactat
    30241 ctttcaatgc ttgcgtacca taagtcaaga gacgatcaat gcacattttt ccgatttgga
    30301 ttcctaatct atccgtgtag cctagatcat cgccacgagc agaaaaagta gattcgactt
    30361 ctttggataa agcatcgcca atacctgccc ataagtattt atcaggtgct tcggcaataa
    30421 ttgctgtatc aatgaaggtg tgtacaggtg gttttgaagg aaagaagagt ccgtccatta
    30481 cgccttcttc gttatagatg acacataccg cagtgacggg cgaacagttc gaaccaatag
    30541 tgggaaaggt gaagactggt ttagctagtt tttcaccaat gacttttaca gtatcgcaag
    30601 cacggccacc accgactgca aacaggacgt ctgctttttg gacactttca tgctggatca
    30661 actgttcaat atttccataa gttgaattac ccccgtacca gagactggcg acaacctcta
    30721 tttcctgtgt caaagctact tttattttgt tttctgcctt tgaaagtgca gtcttccctc
    30781 caatcagcac tacttttgtc ccatattctt tgacgattcc atttgctttt tcatacgcat
    30841 ctgttccaat ggtataattt ggtaagaaaa cactttgact catattcatt tccttctttc
    30901 ttcgttgaaa cgggttaaaa ttttaaagag tgatcgatct gactgcggct gtagatggag
    30961 tagaggtgaa cctaagacag gataagtgat gaataaggtg gcatgaacac cttgaaatca
    31021 tcaataagta tcctaaaaac gaacaagtac aaaaacattg aaaacgacaa taatgaattt
    31081 ttgttcctct tagtatttct accgattccc tttgcttttt tgtaattatc taaaaattct
    31141 aaaaattaag attattatat gaaaacaggt tttatttgtc aattcataat tggttttttt
    31201 taaagcaaaa gataatctat atcatgatga acaaacagag ttttttcctc caattgatgg
    31261 ctttcctgat ctttcctatt ttgaataaag tgtttctgta taattttttt attttataag
    31321 taagataaat aatgaaagaa tagagatact gattggtagc taaagatttt tgagcgagaa
    31381 catttcgttt tttcaaaagg actgttagaa taagcaagaa caagggggaa gacgtatgat
    31441 aatcagtgaa tttgaccgta ataatccagt attgaaagat cagctttctg atttactgag
    31501 actgacttgg ccggaagaat atggagacag ctcggcagaa gaagtagaag aaatgatgaa
    31561 tccagaacga atcgcggtag cagcggtaga ccaagatgag ttagtaggat ttattggtgc
    31621 aatccctcaa tacggtatca caggttggga attgcatcca ttagttgtag aaagctcccg
    31681 acgaaagaac caaataggta ctcgattagt caattactta gaaaaagaag tagcttccag
    31741 aggaggaatc acgatttatt taggtacgga tgatttagac catggaacaa cgttaagtca
    31801 aacggacctg tatgagcata catttgataa agtggcttcc atccagaacc ttcgtgaaca
    31861 tccgtatgaa ttctatgaaa aattaggtta taaaatcgta ggtgtcttac caaatgcaaa
    31921 tggctgggac aaaccggata tttggatggc aaaaacgatt attcctcgac caaattctca
    31981 ataataaaaa gaggttgtga cagaagtaat cagcttcaag aaataagaag gaatttacga
    32041 aaattacttc ttgaattttt gtgaaattcc aacttatttc cgaagaagct acttttggaa
    32101 caccgtgtac cagaggttgt gaaaaagtcg cttagtttcg agtagtaaga aaaattttgt
    32161 gaaaatggct ttctacattt ttgcataaat ttggcttaat accgagaaac tggcttttga
    32221 acaccgttta ttcagataag ggactgtgac aagacttttg tcacagtttc tttttgttta
    32281 ttctttttta tctttgtatg gcaataatag acaatataac gaaaattatt taatggcttt
    32341 tggaagacca tggaaaacct tgtacaaagc tattttttct gaaaaattcc ttgaaacctc
    32401 acgaaaaaat cattatttta tgaaaaagac aaaaaaaagt gttgattttt taataattat
    32461 tcattaaact cttaaacaac ttcagaaaat attaattatt ctgaaaattc caataaaggg
    32521 gtacgtaaaa tgaaaaagaa atttacattt ggtttggttg cggtatgcgg ccttgtactt
    32581 gctggatgtt atggcggcag ttcagccaca agcagtagtt cagcaaaaag cggttcagca
    32641 gatggaggag gcgtatttaa cttagtcgtg cctcaagaaa tgcctacagc tgacttatca
    32701 gttgcaacag atacaatcag ttttacagca ttgaataacg tttatgaagg aatttaccgt
    32761 cttgatgaag acagcaaacc acagccggca ggagctagcg agttggcaga agtcagtgaa
    32821 gacggattaa cttacaaaat caaattacga gaagacgcaa aatggtcaaa tggtgatcct
    32881 gttacagcag cggattacgt ttatggctgg caacgaacag tagacccagc tacagcttct
    32941 gaatatgctt acctgtatgc gccagttgaa aatgcagaag acattacagc tggaaagaaa
    33001 gataaatcag aactagggat caaagcagtt ggtgactatg aattagaaat caaattgacg
    33061 aaacaaacac catatttcca atatctgctt gctttcccat catttttccc acaaaaacaa
    33121 tccgtagtgg aagaaaatgg ggatgcctat gcatctgcaa gtgataaagc tgtttataat
    33181 ggaccattca cattagaaga ttttgatgga ccaggaacag atacagaatg gacttataag
    33241 aaaaatgatc attactggga caaagataca gtaaaacttt ctgaaatcaa agtcagtgta
    33301 gtaaaagaat cttctactgc attgaactta ttcaaagatg gccaagcaga tgacgtgatc
    33361 ttgtctggtg agttagcaca gcaaaacgca aacgatccag cttatacttc tgttaaagaa
    33421 gcgcggacaa gctatatcga attcaatcaa cgtgaaaaga attcaccatt caacaatgtg
    33481 aacctaagaa aagctatttc ttattctatc gatcgtgaag ctttagtaaa acaagtacta
    33541 ggtgacggat cagttgtctc tacaggattg atcccatcag atatggtaaa aagtccaaca
    33601 acgaacgaag actttgcaaa agaagctgga aaattagttt cttatgacaa agataaagca
    33661 aaagaatatt gggaaaaagc gaaaaaagaa ttgggcgttg attctttaga atttgatttg
    33721 atggcttctg atgatgattc atcgaaaaaa gtaatcgaat atgttcaaaa ctcaatccaa
    33781 gaaaacttgg atggcgtaac agtcaaacca acacctgttc cattctctgt acgtcttgac
    33841 cgctcaactt cgggtgattt tgacgcagta ctaggcggat gggctgctga ctatgcagac
    33901 ccaagcagct ttactgattt gtttgtcaca ggtaattcat acaaccgtgg tcgctggagc
    33961 aatgcagaat atgacgaagc agttaaagca gcttcatcaa cagacgctgg cgatgaacaa
    34021 gcccgttggg atgatttcca aaaagcaatc aagatcatct ctgatgatat gggtgtcgtt
    34081 ccggtgtacc aaaaagcaga aggtcaccta gtgaatgaaa aaatcaaagg tatcgttcac
    34141 catgcggcag gcgcttcatg ggattacaaa tggacatacg ttgaagaata atcgttaata
    34201 ccgtgagcat gagaaaaaac gaggctgcgg caaatgtcgc aacctcgttc tcatattcac
    34261 ttatcctaac aaagaaaaaa gcatgaaaat agcagaaaga gcaattagta ttccggcaat
    34321 gatcagccaa aagctgtaca taccgtagct ggcagacgag agcgaggaaa attctggttt
    34381 tttctttcgg ttccttgttc gtgcaagatg gaccgatcgc tgaaaatgat cgaagaaacc
    34441 cgaagaaaag acccataaaa aaccgccgat aatcagaaac ggcaatgacc ataagaatag
    34501 atcattagat aattgaatga gtgtaaagga atggttgatg agatttttta ttaaaataac
    34561 cagaatcagt agaaaagcta ctgcgtaggg gatagatttt tttttcattt gattgctcct
    34621 ttatttttgg ttcattatct aataatgtag cgaaacatct gtcagaagtc aaaagctagg
    34681 gggaaacatt agtgaatagt tatatcaaat atgtattaaa acgtgtcttt ttcatgatca
    34741 tcacgctttg gttaattgca acaatcacct ttttcttgat gcaattgctg ccgggcacgc
    34801 catatacgaa tcaggaacgt ttgagtcctg aaacaatcga gatgctaaat aaacaagtcg
    34861 gtttggataa accagttatc gtacaatatg ggatttatct ttctaatttg cttcaaggag
    34921 attttggaat ttccttccaa tttaaaaacc agccagtcgc acatttgtta gctggaagaa
    34981 tcggaccatc cttgcagtta gggttacagg caattatctt tggaacagtc ctagggacga
    35041 ttttaggaac gatctctgcc atgaagcaaa atacatgggc agatacatct tctacactcg
    35101 tagcgatatt aggtcgttcc attccaaact ttgtatttgc tgttttatta caatatatct
    35161 ttgcaatcaa attacaagtt ttgccaatcg caaaatggga tggctttgtg tacacaatct
    35221 taccaacaat tgcgttggcc atgtcgccgc ttgctgactc tgctcggttt atccgtacgg
    35281 aaatggtgga agtactgcat agtgattatg tggaattagc aaaagcaaaa ggattgagcc
    35341 gttgggaaat cgcctttaaa catggtcttc gaaatagttt gattccattg atgactttat
    35401 taggaccgtt agctgtagca ttgatgaccg gatcactggt ggtagaaaat atctttgcta
    35461 ttcctggtat cggggaacaa ttcgttaagt caatcacaac aaatgattat cctacgatca
    35521 tggctgtaac gatcctttac tcatttatgc tgatttttgt tattttgatc gtggatctat
    35581 tgtacggtct agttgatcca agaattcgtg tttcagaagg gagccgagga taaatggaaa
    35641 tgataccaaa gcgttatgaa acagttgcag atatccctgc ggatgaattt cttccattac
    35701 aaaaaaatac cgaagaagaa cgtgaacaga ttactgcacc ttctttgaat tttatccaag
    35761 attcatggcg ccgtttaaag aaaaacaaag ctgccgttat ttcaatggtt ttactattgg
    35821 tcatcatttt gatctctgtg atcacaatct ttgtttctcc tcatgatcca actgcccaaa
    35881 acgtggctta tatcaatttg cctcctcgta ttccgggaat caatatcgat ggattgaatg
    35941 gaaaagcaat ggttggtggt gaacttgttg ataaatatgc tcaagcaaac gtcccttcaa
    36001 acgtaaattt ctttttagga acagacggtt tgggacgtga tgtattaagc cgcttattta
    36061 tgggaatgag aatctcgttg ctgatcgcat ttattgctgc attactagat gtaacgattg
    36121 gtgtagctta cgggttggtt tctggtttgt taggcggacg tgtcgataac gtgatgcaac
    36181 gttttttgga aatcttatca ggaattccaa acctcgttgt catgattttg atgttggtcg
    36241 tttttgaacc aggaattttt tcaatcgtgg ctgctatggc catcacaaac tggataccaa
    36301 tggcacgtat cgttcgtgca caaacaatga aattaaaaga tcaagaatat gttttagctg
    36361 gattgacatt aggtgaatca agaatgaaaa ttgcattcaa acatattttg ccgaatatct
    36421 ctagtgtcat tattattcaa atgatgttta gtattccatc tgctattttc ttcgaagcct
    36481 ttttaagctt tatcggttta ggtcttacgc ctccgtcagc ttcattagga acgatgttga
    36541 gcgaagggta caagacattc ctgtatctgc cttatctatt atggattccg gcagtaactt
    36601 tatcggttat catgattggc tttaacttac ttgctgatgg attgcgtgat gcctttgatc
    36661 ctaaaatgaa agagtgaaga cgatgacgaa aattttagaa gtgaaagact tagaaatctc
    36721 ttttgatacg tatgctggaa aggtacgagc gattcgcggt gtcaattttc atttgaataa
    36781 aggagaaaca ttggcgatcg ttggggaatc tggaagtgga aaatcagtga cgaccagaag
    36841 catcatgcgc ttgctgtcaa gcaacgccaa tatagatgct ggtcaaatcc tctttaaagg
    36901 taacgatatc gttggaaaat cagaaagaga gatgcaaaaa atccgtggta aagaaatagc
    36961 gatgattttc caagatccaa tgacctcttt agatccgacg atgcccattg ggaagcaagt
    37021 cgctgagtcc cttagaaagc ataataaagt ttcaaaaaaa gagggacaaa aagctgcatt
    37081 agaattgctt aaattagttg gaatacccga agctgagaaa cgtatcaaca gttatccgca
    37141 tcagttctca ggaggtcagc gtcaacggat cgtgatcgcg attgcactgg tatgttatcc
    37201 ggaaatcctg attgctgatg aacctacaac agcgcttgat gtgactattc aagcacagat
    37261 tttggagctg ctgaaagaaa ttcagacaaa aatcgataca tcaattatct ttatcactca
    37321 tgaccttggt gtagtagcga atgtcgctga tcgtgtcgct gtcatgtatg gaggaagaat
    37381 cgttgaagtt ggaacatcgg aagaaatttt ctacaacccg caacatccct atacttgggg
    37441 actgcttggt tcaatgccga cattagatag tgcgaacgat cgattgtatg ctattcctgg
    37501 ttctccaccg gatttattga acccgccaaa aggagacgca ttctatccaa gaaatgaatt
    37561 cgcgatgaaa atcgatgcag aacaagaacc accatttttt gaactatcaa aaacacacaa
    37621 ggcagcaact tggctacttg ctccgcaggc acccaaagtg acaccgccag aagaaatcca
    37681 acgtcgctgg gctatcttta aagagaaaca aaaacatact tacggtcaag gaggaattgc
    37741 tgatgccaaa taaactactt gaagttaaag gattgaaaca gtatttcaat gtaggaaaaa
    37801 agaatgaagt acatgctgta aatgacatca gctttcacat ttatgaagga gaaacattcg
    37861 gtttagttgg agaatctgga agcggaaaat ccactactgg ccgtacgatc attcgcttga
    37921 atgaacctac tgatggtgag atattattcg acggtcaaga tataacgaag atcaaagata
    37981 aaaaaggttt gacgaaattc cggcatgatg ttcagatgat ctttcaagat ccatacgctt
    38041 cgttgaatcc tcgtatgaaa gtcagagata tcattgccga aggaattgat gttaatggac
    38101 tagctaaatc atctgaagag cgtgcaaaaa aagtcgatga tctattgaga actgttggat
    38161 tgaatccaag ccacggtact cgttatcctc atgaattttc aggtgggcaa cgccagcgta
    38221 ttggtattgc acgagcattg gcagtaaaac cgcgttttat catttgtgat gaaccaattt
    38281 ctgcactaga tgtgtcgatc caagcccaag tggtcaattt gttgcaagat ctccaaaaag
    38341 aacatcaatt gacctatcta tttattgcac atgatttgtc gatggttaaa catattagtg
    38401 accgaatcgg tgtaatgcat aacggcttgt tattagagat gggaacaagt gatgaaatct
    38461 ataatcacgg tgttcatcct tatacagaaa gtttgttatc tgctattcct ctaccagatc
    38521 cagaccatga gagaaaacgc agaagaatca aatatcaacc tgaaccagat gacggacaag
    38581 tacgtcaact tcgtgaaatc gcaccagaac attttgtcta tgcaactgag caggaagtcc
    38641 catattacgc aaaaaaacta aaacgacaaa aggaatctct tctggttgct aactaggagg
    38701 gacatagatg ctaaaagctt ttaaattccg tatgtatccg acagaagaac aaaaacagca
    38761 attgattcgt acttttggat gtgctcgatt tacctataac catttgctga aaaagcggca
    38821 gaaaagttgg caacaaacag gagtagccaa tttttcgctc acacccgcta cattaaaaaa
    38881 agaataccca ttcttaaaag aagtagacag tcttgcttta gcaaatgcac agcttaattt
    38941 ggatcgggct tttcgcaatt atttcaaggg acgtgccagc ttcccaaagc ttaaaacgaa
    39001 aaaaagtatg tggcaatctt atacgaccaa caaccaaacc cgtacgatct atctggaaaa
    39061 tggctactta aagttaccaa aacaaaaaga actaatcaag ataaatcagc atcggccagt
    39121 tgaaggatcg attcgctccg ctacgatttc tgctcgatat aatgaagaat tttatgtcgc
    39181 actactttgt gatgtttcgc cagtaaaaaa agaatcttta gctaaatgga tcgggatcgc
    39241 ctatcatccg aagacattga tccaaacatc tcgacctcta gaagtaactt taccaaaatt
    39301 tcaccagaca gaagaaaagc tgcaacatgc acagcggaaa ttgaatgtga aagtccgctc
    39361 cgctcaccat agaaagatca ggttagatca ggcaagcaat tatcagaaac aaaagagaaa
    39421 agtaatggat ctttatctga aacaaaagaa ccagcgagaa gattatcttg aacaattatc
    39481 tgggaaattg gtcaaacaat atgactactt atttgtagaa tcttttccaa aagaagaggc
    39541 acatgctgat ttttctattc acgactggca taaattaata acaaaattgc gttataagtc
    39601 ccaatggtat aataaaaaat ttcttttgat caataccgac ggagcagaag aaagcaattc
    39661 cgtaagaaag agccaagtag tagaaaaaat gggcagacat tcggttatca agggataaaa
    39721 aatgaatgaa actgatagga gcgttagggt tagccttgtt aataaaaagt cttaatgact
    39781 tttgtttcta ggaatttttc ttttgaagaa aagctcacta attatgacaa accaataaaa
    39841 caatagcaga aaaagttcgt acgagctttt tctgctattg ttaatttttt attcagaaag
    39901 tttacgaata catcaaaatt ctgaaacaaa aaacgtaact cacaaagagt tgtttttgcg
    39961 ttttttcttg aatgattagg tctgaatctt ttgctcacaa ccttattcat ggtgccccgg
    40021 cttgagctga tagatttttg aaggacggcc gattcctaca ggacgttcac cgatctcatc
    40081 gaaatattgg agcatagctt tcttaaaatt ggaatgatcg atcgttttat aatcgatccc
    40141 taagaattta gcaaatactt ttcgagcttc cgtaatcgtg aaatctttac ctaaaacttg
    40201 tagaacttgc ggctcgtgtt ccattttatt gactacacgg ttgaatgctt tcaagatgat
    40261 ttgactatgg tcaaaagcca aagtatcttt gccagaagac tctccagtga ctaaatcaag
    40321 cgagatagcc acttctccgc tagataaatg gatcttgtta ctatgacgtt ctagtgtgaa
    40381 ccagcgtact tccttggcat catctccggc gattagcggt tcttctccaa taaaggctaa
    40441 gtagctgact gtgacgaccc agcctcgcgg atctcgatta ggcgtactga atgtatgcag
    40501 ttgctcaata ttttcttttg aaataaccac accagtttct tcctttgttt ctcttaagac
    40561 gctttctcca gttgactcat ccttttggac aaagccacca ggcaatgccc atgaatttcg
    40621 ataaggatgc ccttttcttt ggatcaacaa aactttcagc tgatcttctt ctttgttata
    40681 gcacatcagt acgatatcga cagtcaaaga gggcttgtca tattctggac gttcctgttt
    40741 ttgataccag ttaagaaatt cttcttcact tgctttatgt tcataatata atttttcttc
    40801 ttctttagaa gcaaaacggt tcatctgacc acctccattg acagtaaaag tactttttac
    40861 cttattgtag cagactctga aaaaaaacca aggatttact tgaaaaatct aggttatcat
    40921 ttaaatatga aaaataaatg gaagtatgag attgaataaa aagaaaagca gataaaacgg
    40981 caatacttta taccgctctt cacgaatggc aaagaagcca caaataacga tatatacgtc
    41041 aatgataaaa cgcaaaatcc aagctgctgt cataaaactg ttcaaatgcc catggaggtt
    41101 aaaataacca tacatacgaa tataaaaata gctgaatatt aaatgtgcta atgaaagaaa
    41161 agcaatacta agtgtaaaaa aaagatgttt cttctgcatg attgttccag tcccttacta
    41221 agatagatag tctttattat accacgtgtg aggggagaaa taaaaagccg ttttttagta
    41281 gatatgaaac aaaacaaaaa cccgcattta ttcaacctat tcatcctttt aaaggataga
    41341 ttgaacgtag atagaagtcg tttatccagt ctttttcatt ttgaaaaaaa gctaacagca
    41401 tgcttttttt atggtatact agcaaggaaa cgaattcgca tcatgcgata aaggaggaag
    41461 agccccgtgg cagaaaagga aactttttat atcactacgc caatctatta tccaagcggc
    41521 aaacttcata tcggcaactc gtatactacg attgcatgtg acgcaattgc tcgttataaa
    41581 cggttgatgg gctttgatgt gttttatctc actggagtgg atgaacatgg tcaaaaaatc
    41641 gaaacaaaag cagaagaact aggtgtaaaa ccgcaagaat atgtagataa aatggcggct
    41701 gatgtcaaga aattatggaa aacgcttgat atcagttatg ataaattcat tcgcacgaca
    41761 gatgattacc ataaagcagc tgttcaaaaa atatttgatc gtttattaga acagggagat
    41821 atttacttag gtgaatatga aggctggtac tctgtttctg acgaagaatt ctttacagaa
    41881 acacaacttg cagaagtgta caaagatgac gaaggtaacg tgatcggtgg taaagcgcca
    41941 agtggacacg aagtagaatt ggtaaaagaa gaatcatact tcttccgcat gagcaaatac
    42001 gcagaccgtc tattggaata ctatgaagaa catcccgaat tcatccagcc agaatctcgt
    42061 aaaaacgaaa tgatcaacaa ctttatcaaa ccaggattag aggatcttgc agtttcacga
    42121 acaactttta cttggggagt accagtcaag agtgatccga aacatgtggt gtatgtatgg
    42181 atcgatgcat tatccaatta tattactgca ctaggatatg gctccgaaga tgaaagtcta
    42241 ttcgaaaaat actggcctgc agatgttcag atggtcggta aagaaatcgt tcgctttcat
    42301 acgatctatt ggccaatcat gctgatggcc cttgatttgc ctctacctaa aaaagtattt
    42361 gggcatggct ggctattgat gaaagacgga aaaatgtcta aatcaaaagg aaatgtcgtt
    42421 tatcctgaaa tgcttgtgga acgttatggt ttagatgcac tccgttatta tttgcttcgt
    42481 gctgttccgt ttgggtcaga tggtgtcttt acgccagaag attttgtttc ccgtgtcaat
    42541 tatgatctgg caaatgatct agggaactta ttgaatcgaa cgattgctat gatcaacaaa
    42601 tattgtgatg gactcgttcc tgactatgcc tcacttgtca ctccatttga tagtgaactg
    42661 tctacgacgg ctgctaacgt tgtcggacgt taccatgatg caatggaaaa aatggaattc
    42721 aatacagcat tggctgaaat ctgggtgctg atttctcgtg caaacaaata cattgatgaa
    42781 acagaaccat gggtattagc aaaagacgaa gaaaagaaag ctgaattgaa tagtgtcatg
    42841 atccatttag ctgaatcttt gcgtatcgca gcgatattac ttcagccaat catgacagaa
    42901 acgccagaga agatcttcaa tcaactagga ttggactctg aaacaatgaa tcttgaagga
    42961 ttacactttg gcgaatttcc ttcaggaaca aaagtagttg caaaaggtac accaatcttc
    43021 ccacgtttag atatggaaga agaagttgct tttattcaag aaaaaatgtc tgaaggtact
    43081 caaacaaacg aagatacagt caaatgggat ccagaagaaa cagaacttgt ttcaacgaaa
    43141 gaaaaacaaa tcaaatttga tgtatttgaa aaagtagaac taaaagtagc agaagtcatc
    43201 aactgtcaaa aagtagaagg ggcagataag ttgctgcaat tccgactaga tgctggagac
    43261 agccaagacc gtcaaatctt gtcaggaatc gctgaatttt atcctgatcc aagcgaattg
    43321 atcgggaaaa aagtcgtcat tgtagcaaat ctgaaaccac gaaagatgcg tggacaaatc
    43381 agtcaaggaa tgatcctttc tgcagaagca ccagatggct ctttacaagt aatcgaagca
    43441 ccaaaatcca tgccaaatgg ctcagaaatc gcatagaaat tcaaaggggg tatgacacta
    43501 gttgtgtcat accccctttt tccgaaattt gagaagcaat tttcgtaaat tccttcttat
    43561 tacttgaagc caatcatata atacagaaac agagaactat ccaaaataaa tcctagaaaa
    43621 agaagtacga gcttcgctga tttttgttaa tttagaataa tactaatagg aatcgtaaaa
    43681 acagaaaaaa agcataatga taaagggtcg ggcagatttt aattgattca tctggtactc
    43741 ttttttattg tccttacatt cataaagttt gaatgcaatg actttattac atctatattt
    43801 atatctaaca gtagcgttga tgtgttaatt ataagttcta tcactttatg ttcaattagt
    43861 ttgtgctctt atatgtgtga ttgaaaatat agataaaaaa acaatcatcg gctttgactt
    43921 cgatgattgt tttctttatt ttgtaaaaat cctatcactt gattttatgg taacctttta
    43981 tttttgtctt caaacggctt ggtaagagag cagtaagcag tgcaaatggg atcgaaaaga
    44041 cataccagaa aatcgtacgt ccgataccat aatgttgata gagctttgtc aacatcacgt
    44101 gtaacaagat caaccctaaa agcaaggagc cagctataaa ccaatgatta tcccaatgca
    44161 tgacttcact aagtgccatc actccaaaag gatagaaata aaaatagatc ccgactaagg
    44221 tcatccgcca gttctttgta aatgttccga tattcaataa aaagaaaatc gctgaaagca
    44281 aaataccgat aggcggaaaa agcccaacca aaaaggaata caacatcccc cacaagatca
    44341 tcacaggacc tttgatcaat gcaacgattg cgatgaacaa agtcagcaat attagttttt
    44401 gtgataacgt tgcaacagtc attaatccaa ataaaattaa tgtgaaccaa tgccaatggg
    44461 actgctgttg ttctttacgg gaaaaatcga cccggttgga taaataatct gctaatttcg
    44521 gataagaacg cttaaaatcc ataaactgtt cctccttcgt ggaaaaggta ggtttagtat
    44581 acgaaaaata aaaaagaaat acatccgtct taagagggag tttttcactg aaagtggaga
    44641 aaaaagaatg gtaaattaaa atattctcag ttatactgaa aattatacca aatttcaaag
    44701 aagaaagagg atgggaatga aaggcaaact aaaacgagaa atcaatctgt ttggcgcatt
    44761 agctaccgtt atgggaaccg tgatcggtgc aggcgtcttc ttcaaaactg ctgctgttac
    44821 tgctagtact cagtctacaa gtttgacatt gctagcttgg cttttgggtg gtttcttaac
    44881 gatctgtgct ggattgacag tggctgaatt agctacagca atcccggaaa ctggtggagc
    44941 tgtaaaatat attgaagctg cgtatggaaa attgcccagc tttttattag gatgggcgca
    45001 aagcttgatt tactttcctg ctaatattgc tgcattatcg attatctttg cgacacaatt
    45061 gacgaactta ttacaattat ctaccgatta tcttttgttg attgcagtga tcaccgctgt
    45121 ttctgtgaca gggttgaatt tgttagggac aaaagtcggt gcttctgtac aatcagtgac
    45181 gttgattgtt aaattaatac caattgctgt gattgtcata tggggattat tgaccccagg
    45241 acaaggaact gtccagttat ttccaatcga agctggaaaa gatgttactt ttgtcgaagg
    45301 attgagcagt gcgttgttag caacgttgtt tgcttatgac ggctggttag gtgtcggtgc
    45361 aatggcaggg gaaatgaaac ggccggaaaa agatttgcct aaagcaatta ttcttggttt
    45421 gagttttgta acagtcgttt atctattgat caattttgtt tttttgaaaa ctttgccgat
    45481 tgatcatctt gccggtaatt tgaatgcagc ttctgaagca tcagacgtca tttttggagg
    45541 aatcggtgga aagctggtca ctattgggat cttgatctcg gtatacggtg cattgaacgg
    45601 ttatacacta actgggatcc gcgtgcctta tgcgatggct ttagaagacg agctaccttt
    45661 cagtaaacag ctgacaaagc tttcaaagaa gtttacggtt ccttatgttc ctgcggtttt
    45721 ccagttagca gtagcttgta ttatgatgag ccttggttct ttcgactttt taacagacat
    45781 gttgattttt gtgatgtggc tattcagttt actgattttt atcggtgtct ttattttaag
    45841 aaaaaaagcg ccggaattgc cacgtccata taaagtacca ctttatccaa tcgttccgat
    45901 tattgcgatt ctcggtgcta ttttcatttt aggtatgacg atgatgacgc aaacgaaatt
    45961 agcattgatc ggtataggtg ttaccttgat aggtatccca gtctattatc aaaaaaagaa
    46021 aaaacgctca gaagagtaaa atatttcaac aacagacaga aaaagtacga actaggtcct
    46081 ctagatcttc gtgctttttc tatttcaata aaacaagttc ttctattttg atttttgcta
    46141 cttctgcaag tagtgcttat gtgctaaagt aagaatgaaa aggagagata aacatgatat
    46201 ttgattctca tacccattta aatgctgaac agttcaatga agatattcca gaaacgattc
    46261 agcgagcaca agaaatgggg gtaacgaaaa tggcggtcgt gggcttcgat acgccaacga
    46321 ttgaaaagtc tttgcaatta agccatgact atccaaatat atacagtatt atcggctggc
    46381 atccgacaga ggctggcagt tatacgaaag aaatcgaaaa taaattacaa gaacaattga
    46441 ctttaccaaa ggttgtagca ttaggggaaa ttggcttgga ttatcattgg atggaagacc
    46501 cgaaagaagt ccaagataaa gtatttcgca gacagattgc tatcgcaaaa gaaatgaacc
    46561 taccaatcag tattcatact agagaagcac ttgaagacac gtatcaaatc ctaaaagaag
    46621 aagatgttcg agatatcggt ggaatcatgc atagtttcag tggtgattat gaatgggcaa
    46681 aacgatttct tgacttaggg atgcatattt catttagcgg tgtcgtcact ttcaaaaaag
    46741 cattagacgt ccaagaggct gcagcaaatg taccaatcga acgattactt gtggaaacag
    46801 atgcccctta tctggcacca gttcctttta gaggaaagcg aaatgaacca ggctatactc
    46861 gttatacagt agaaaagatt gctgaacttc ggaatcttcc gacagaagaa gtggctgccc
    46921 aaacatggac aaatgcgcac cgattatttg gtctaagcga acatggataa gatgaagatc
    46981 caagagatta tagtcgttga aggaaaagac gatacaagaa ggctgcggga agtagttgat
    47041 gcagatacga tagaaacaat agggtctgca atcaatgaag agatcctgat gcaaattgaa
    47101 catgcccaag agactcgtgg agtgatcgtt tttaccgatc ctgatttttc aggagaaaaa
    47161 ataagaaaaa tcattatgga agctgttcct caggcaaaac atgctttttt gccgcgcaca
    47221 caagctaaac caaagaaaaa gggaagcctt ggtgtcgagc atgcaagtga tgctgctatt
    47281 ttagaagcat tgaaaaaggt cgtgacgcca gacatttccc aaacggctgt ttctgaaatc
    47341 actagacaag accttttaga ctatggttta atagctgggg cacaagcaaa agaaaaacga
    47401 gaaaaactag gtgacgagtt gcgcatcggt tacacgaacg gcaaacaatt ggaaaaacgt
    47461 ttgaagatgt ttcgtattac gccgaaagaa ctcgcccaag caatgaaaat agtggaggaa
    47521 caacatgagt gaatatcgtg aaattgcgac accctctaga acaaaagaga ttttattgaa
    47581 acatggtttt tcatttaaaa aaagtttagg acaaaatttt ctgactgaac caaatatttt
    47641 aaggaaaatc gtagaaactg cgcaaataga tgaacatacg aacgtgatcg aagttggacc
    47701 aggaatcggt gcattgacgg aacaattagc caagcatgca aaacaagtcg tagcatttga
    47761 gatcgatgat cgtttgatcc ctgtattggc tgatacgatg caaccctatg acaatgtgac
    47821 tattgtacat caagatattt taaagaccga tttgtcaaca gctgttagag aaacatttca
    47881 tgaggagctt ccgttaaaag tcgtagcgaa tttaccttac tatattacga caccgatcat
    47941 gatgcatttt cttgaatcag atttggttgt ggatgaacta gtcgtcatga tgcaaaaaga
    48001 agtagctgat cgtatctctg ctgaaccagg aacgaaagct tatggttcat tatcgattgc
    48061 tgttcaatat tatatggaag ccagtttagc attcatcgta ccaaaaacag tatttgtccc
    48121 tcagccaaat gtagattcag cgattttgaa actgacaaga agagatatac cggcagtcga
    48181 agtgacagac gaaaaagcat ttttccgatt gacaaaagcg gcatttcagc aaagaagaaa
    48241 aacgctttgg aataacttgc agcattcgta tggcaaagat gaccagacaa aagcatggtt
    48301 agcaaaaagc ttggaaacag ctggaatcga tccaaaacgt cgtggggaga ctttgtcatt
    48361 acaagaattc gccgcattaa gcaatgcgat gtcagaaaat atgcagtaaa aaaagaggtt
    48421 gtgacagaag ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat
    48481 agttcctcat gtttttcgtt tgtttgggct tattaccgca gatgcaagct tttgaacacc
    48541 gtttaagaaa gaggttgtgg gcctgccgtt taactctaag tcacaaggaa caatttcaaa
    48601 aaacagcttc tcatgttttt gagttagttg gtcttattac ttgatgcaag cttttgacca
    48661 ctattatgcc gaacaaggag atgtgacaca aattttgtca catctcctat ttttgtttct
    48721 tgatcaaaaa attcttatac ttgatactca cactcatttt gtatggattt agaaaagaat
    48781 atgtgtcttg acagttatta gtaagtgagt tatactaagt cgacatttat gtgtcaagac
    48841 atattaggag agagaaaaaa tgagaaaaaa ttcagttcga aaactaacga tttctgcttt
    48901 attgattggg atgggggtca ttatcccaat ggtcatgcct aaaatcatga ttccaccagc
    48961 ttcctttact ttggcgtctc atgtgccatt atttattgcg atgtttttta caccaggagt
    49021 tgcagtggct gttgcgctag gtacgacatt tggtttcttt ttaacaacgc cggttatcat
    49081 cgcattgcga gcattgtcac atcttgtgtt tgcgttgatt ggggcttggt acttgcaaaa
    49141 gcatccgagt atcgttttaa aaaatggaca gtttactttt gctaattggc gtttccaagg
    49201 gttcaatttt gtgatcggtg tgattcattc tttagcagaa atgctagtag tcagcatctt
    49261 ttactttatt ggtaatatgc ctgaaacata ttattctcaa ggatattttt atacagtatt
    49321 catcttgatg gggattggtg ggcttatcca cagtttagtt gattataata ttgcttattt
    49381 tatagcagga acactcagca aatattttga tatccccgta tttacggcag caaaaaaaga
    49441 aaatcggaaa gagtcgattc aagggtacgc gaagaaaacg acatattaga catgatctct
    49501 caaaaaaaaa actctcatct agtaatggat aataaatcct ctaagatgag agttttttgt
    49561 cctaaaaaga gctgcaccaa catcttctgg cacagctcta acagggggca atttatggaa
    49621 gtttgatgac ttgttctgtt tctttatcaa agaagtggcc tttgctgatg ttgaaggcaa
    49681 ggtcgactat ttcgcctggt ttatggaaat ctcttgcatc tacttttgag atgaactcag
    49741 tagaaccagt ttttgtgtaa agcatcgttt cagctccaag taattcggaa acgacaactt
    49801 ctgatttcac tacggcttca ggtgaagctt caagggctac ttgttcactg tggatgtctt
    49861 ctggacgaat accgaagata acttcttttc cttcataacc tttttcaact aatactttgt
    49921 tttttccttc aggaatacga agcttaagcc catgtccatc tgtgataaca ccatttttca
    49981 atgtcacatt aaagaagttc atggcaggag atccaataaa gccggcaacg aacatattga
    50041 cgggtgtatc ataaacttct ttcggtgtac cgatttgttg gataaatccg tctttcatga
    50101 taacgattcg gtcagccata gtcattgctt ctgtctgatc gtgagtaaca tagatggtcg
    50161 ttgtttcaag acgctggtga agtttggcaa tctcagcacg catggctaca cgtaatttag
    50221 catctaaatt tgataatggc tcatccatta agaagacttt tgcatcccga acgattgccc
    50281 gtcccaatgc cacacgttgg cgttgtccac cagataaagc agctggtttt cgtttcaagt
    50341 attctgtcag acctaagatc tctgctgcat tgtccacacg ttttttgatg tctgctttat
    50401 catatttacg taatttcaag ccaaaagcca tattatcaaa aacagtcata tgaggataca
    50461 atgcgtagtt ttggaaaacc atggcaatat cacggtcttt aggtgccacg tcattcatga
    50521 cttttccgcc gatatttagt tctccttcag agatatcttc cagtcccgcg atcattcgca
    50581 aagtagttga ctttccacaa ccggaaggac caacaaaaac gataaattca cggtctttga
    50641 ttgatagatt aaaatcagtt acagaataat tttctgcatt gtcatatttt ttatatacgt
    50701 ttttcagagc catttctacc ataatacgtt ccacactttc ttttttagtt ttattaacta
    50761 tttaaagtat aaatgaaagc gttaactaac ttcaatgtca tgttgaacaa gaattttttc
    50821 ttttttttgt caatgtgcta gttttaagct ttaataaata tccataagaa ataaaaactg
    50881 atacactgga gtaaataagt atgttaacaa tatcaaaagg agtgtctctt atgaaaatcg
    50941 ctttgatcgc tcatgaccga aaaaaaccta tgatggtgaa attagcaaca gcgtataaaa
    51001 caatattgga aaaacatgaa ctttttgcta ccgggacgac tgggcagagg atcacggaag
    51061 caaccggctt gccgatccat cggtttaaat ccggaccgtt aggcggggat cagcaaattg
    51121 gagccatgat ttcggaggat cagttagatt tggtgatttt tcttcgagac ccgctggctg
    51181 cacagcccca tgaaccagat gtaacagcac ttatccgttt atctgatgtc tatgagattc
    51241 cgttagctac gaatatcgga acagctgagg tgctactaag aggactggaa gccggcttcc
    51301 tagattttcg aagaatcgtc catgaaatag acaagcatcc actttcattt tgatggataa
    51361 gcgtatggaa aaataacgtt taatgttcgc ctatatgtag ctataaaagc taaacaaact
    51421 gataatatgc gatataatac gaacgtattg gataatataa acaataatat tagtttttcg
    51481 tatttgcagt aaatgtgaaa atatgctata gtttctgtgg gaaaagatcc caaaaataat
    51541 acagagtaga aaataaagcg ttaagtgcta agaggatggg atgttgcctc ttggacgaag
    51601 gacgtaatgt tcgcggtttt attttcgcat tcgctgcatg atacgatgta gcagctctta
    51661 aaggagatgc taaaaatgaa gaaacaccgg ttagacgcac gtatgattgc tattatgggc
    51721 ttattgattg cattgatggt cactttgtcc cgactggtag caatcgagac cccatttatt
    51781 aaaatcagtg tcacatttat tccacaagtg atcatgggca ttctttttgg tcctttttgg
    51841 tcagggatag gcgcagtttt agctgattta gtaggaatgg ccctcttctc gaaatctgca
    51901 ttctttattg gatttacatt gaatgcattt attgaaggag caatctacgg attctttttc
    51961 tatcgaaaag agatcacttg gaaaaatgcc attctggcta cgcttagtgt cacgctgatc
    52021 atcaacttat ttttgacacc attatggctt gcgttgatgt accatgtgcc attgttcagc
    52081 tgggtcgttt gggcgccccg cctgttaaaa acagtaatat ggttaccgat tcaatcaatt
    52141 gccatttatt acgtaggacg tagtattcct tacaaaaaaa ttttaagaag tttagcgatc
    52201 cacgctaaat aaaaaacaag cagtcttccc atcccagaag actgcttgtt tttattgtgc
    52261 tgtgaattgt gcttgataga gccgtcggta ataaccatct ttttgaagca gctcatcatg
    52321 ggtgcccatt tcgacaatag ctccctgatc catcactaat atctggtccg catttttgat
    52381 tgtggacagg cgatgggcaa tcacaaaact ggtttttcct tccatcattg ctaagaaggc
    52441 ttgttggatt tttttctctg tcaatgtatc gactgagctg gtagcttcat ctaagatcaa
    52501 cataggggga ttactgatca tcgttcgagc aatcgtcaac agttggcgtt gtccatctga
    52561 tatctttaac ccttgaccgc caatcttagt atctaatttt tccggcaaac gttctacaaa
    52621 ttcatacata taagaggctt ttagggcatc attgatttct gcgtcacttg cttccggatt
    52681 cccaaaacga agattttctc gcaatgtact gtcaaatagc caagtatctt gtaacaccat
    52741 tccaaaactt ttacgtaatg tatcacgttg gatagagcgg atgtcatggt catcgactgt
    52801 aattgttcct tttgttgtgt cataaaaacg catcagcaaa ttaacaagtg tggattttcc
    52861 ggcccctgtt tttcctacta tagcaatggt ttgacctgga taagcagtaa aattgaaatc
    52921 ttcgatcaaa cgctgcttgg ggtcataaga aaaagaaaca tgatcaaaag agacttttcc
    52981 tttgatattt ttgggttcca aggcataggc atctggcaaa tcaggctttt cttctggctg
    53041 atcgatcaaa tcaaatgctc gttctagacc agaaaaagcg gtttgcagtt gtgtcgtgat
    53101 tccagaaagt tcgataaatg gtttagaaaa ctgacttgag tagatcgtaa agctggaaat
    53161 cacaccaaca gtgattgacg aaccactctt caatgccaat aggccgccaa ctaaaccaat
    53221 cgataaataa gcaaggtgat ctacaaaacg agaagacggg tttgtcaagg aagaagaaaa
    53281 ttgtgcccgt tgtccttttt catatagatc agcatttagc agttcaaatt gctgttgact
    53341 agcttcttct tgctgaaaag ctttcacgat tttctggtta ccgattcgtt cggtcacaaa
    53401 gcccgagata tccccaataa tcctttgctg tctatcgaaa tttgtttgtg aagcacgagc
    53461 aacgatccaa ctcacaagga aaataattgg tgtagaacaa agaacgacca atgtcagaag
    53521 tggacttaga cgcatcataa aaataaacga aagaatgatg attgccactc cagaaaataa
    53581 ttgattgaag gccgcagaaa ttgcaatgga aatattgtcc atatcatttg taaatcgact
    53641 gacgatattt ccgtgggagt tttgatcata ataacgaagt ggcaatcgat tcagatgagc
    53701 aaatgcatct tttcttaatt ttgcaacgga taagtaagct aaccgattgc ttaacacttg
    53761 gatgagccat tgactgacta cgttgattaa aacgatacca ccgaatagaa taagtaaatg
    53821 gaacagtcga ttgaagcgga cctgtccttc tccaatcatt tgatcgatac tttgaccaat
    53881 ttgtaacgtc atcacaactg ttgcaatccc attgatgatt cctagtatca cagctagcca
    53941 aatgtctttt gcataggcag taaggtaagg aatgaatcgg cggagcgtct gcaaggataa
    54001 tttttttact ttcataacta ttcttcctcc tgtgatgcga cgatttcctg atattctgct
    54061 gattgagcaa gtaattcttc atgggtaccc tgagcagcaa tcttaccttg atccatcact
    54121 aagatatgat gtgcttcttg aatagagcgg acacgttggg agataataat cactgtactg
    54181 ccaagataag tctgtagcgc cttacgcaaa tccaagtctg tttgataatc caacgcactt
    54241 aaagagtcat ctaaaatcag taatgctggc ttggcaatca aagctcttgc aatcgtcagt
    54301 cgctgttttt gtccgccaga gaaatttttc ccattttcca tgacttttgt atctaaacca
    54361 tttggaagct gacggacaaa ttcttctgcc tgagcgattt tcagagcttc ccaacattct
    54421 ttttctgtgg cgtctttctt accccattga aggttttcac gaatagtccc ggtaaatagt
    54481 acagaagttt ggggaacaag agcaatttgc tgacggagat gatccagctg ccaagaacga
    54541 acatccattc cgtccattat aactgtaccg gaactgacat catagaaacg cggaatcaat
    54601 tgtgtcaaag tcgttttccc gcttccggtt ggaccaatga ttccaaggac tgtatttcgc
    54661 ttcagctgaa atgtaatatt ttggagagaa agaccagaat caggagtata acggaagtca
    54721 acatggtcaa aagcgataat tgcttcagaa gaaaaatcgg gagtagtact gacctcagct
    54781 tcaagaatcg aattttctgt gactagcacc tctttcaccc gatttcctga agcttcggca
    54841 cgtgtgaaga tcacgacgag gtttgaaaca acgatcagtg ccaaaagcat ttgattcata
    54901 taattgatca aagcaagaac ttgtccttgt tgcaagctac caatatttac tttgatcccg
    54961 ccaactgtca gcaaacagat gatcccgaca ttcatgatca aggttgtagc aggtgataat
    55021 agggcagaga tattggaaac acgtaaataa ttgttcgcta gatcatttgt gcttttatcg
    55081 aacttctctg tttctttttt tgtctgcgca aatgcgcgga tgacacgaac accgctaaga
    55141 ttctgactaa cgtgttcatt gagctgatct agtttttctt gcactttttg gtagagagga
    55201 acggtttttt tgatgataaa aaataaaatg attgagaaaa taggcaataa tgctaagaaa
    55261 aacagaccta cttcccagtc gatcacaaaa gccatgacca ctgacccgat acttaaaaac
    55321 ggtgctctga tcaataaacg aatgaccatt gctaaagcta gctgaagctg attgatgtcg
    55381 tttgtcattc gggtgatcaa ggtatctgtt ccaaaatgat tcaactcgtt gtgagagaaa
    55441 gtattgattt ttttgattag ctgattacgt aactctgtac caaatccttg tgaagctact
    55501 gaagcatagt attggcaaat gatagcacaa atcagaccaa tcacagacat agcgaccatc
    55561 cataagccca tttcaatgat ttttcctcgg tcattcattt ttagtccatt atcgatcaag
    55621 gaagccatca ttaaaggcag gacaagttcg aagacagctt caagaaattt gaagaacggg
    55681 cccaaaatga tttgcttacg atagtctttt gcataacgta ataactgaat catatgattc
    55741 ctcctattat ttatttgtcc acaattgaaa aaacaagtac taccacattg tagcttagga
    55801 aatttagaat gaaaagagaa caagcctttt cataaatgaa agttttatta tgaagaagct
    55861 ttagaaattg aatagactat tttttttaaa aaaaagaaaa tgagaaaaca tgccagtctc
    55921 ttcattcata ggaacgtcta ttttacttaa tttttctata aatgaattct gcataaaaaa
    55981 tatatcaagt aaatgtttat agatgaaact ctatttactt cttttttaat ttgttcttgc
    56041 aatctttttt gctacgtaat ttttgtaaaa aagtgggttg agagaaatct aattgatttt
    56101 caaagaagga gtatgaaaat gagaaaaata tttattcgtt tattgtgggt actatcttag
    56161 aggaataaat aatagtggag aaaactatgg tttggcgcag attctatcag gtttgatgga
    56221 acgaagacaa cctcccgaca tcaagtcaaa agctacttga gattttgatc tgaaaataaa
    56281 aaaagaaaac aaggtaggaa catcaatgtt tctaccttgt tttcgtaatc aatgggaaaa
    56341 aactaagagt ggtgtacgta atcaataaaa aggatggtga caacagtacc tctttactct
    56401 ctgaaagcat cataactcgt ttttcctcat tatgccaata aattgttgtt ataccacata
    56461 taaggatttg taatagctaa aaacagacag gaaagttgaa atctgtgaat cttattttgt
    56521 atggaaggat ttatagaacg caaaaatcaa gataaagatg aataaaaatc ctgtttcggc
    56581 tatatattgc gtatctacgc caataaaacg agtttgttct gtcatagcca tataaagcaa
    56641 aggcaaaaat acaactacag cgagataaga tccgatgatt tctcgaaaag ttttccagga
    56701 agtatgtttc ctgtttttat atttatccga tttcattgaa tagtcatagc ctccttattc
    56761 tttcatatgt tgaaattcca gtataaaaac tggaaggaac tgtacgtttt ttagaataaa
    56821 aattataagg gataagtagg ctgctgtcta taataagata tatttttcaa ttctttatta
    56881 aagattttat tgacaaaatg aatccgtttt ctatgatgga ggaggggtga ataagttgtt
    56941 gaagaaggaa attttatgtt acttagagaa ccagacagcc tttttcgatt tagaacatat
    57001 gaacgaggtc tttacagcac aaaggttagc tgatcatttt ggggtaaaaa gaaacacagt
    57061 cagtcattat ttgaaccagt taaatgatga gcaactacta gtcaaaatca attctcgacc
    57121 agtgatttat ttccacaaag aagcttttga aaaacaattt tttaagttac gcacgaattt
    57181 ttatttttct atcgatgatc tcaaagagga acagcctttt ttcgcgcaac caaaagactt
    57241 attctctttt atgatcggat acgacgccag tttgaaagaa agtatcgaac aaatcaaaac
    57301 agctctttac tatccagatg gcggattacc acttttgatt acaggcgaaa gtggcacagg
    57361 taaaagttat ttagttaatt tggtctatca gtattgtctg cttcatgatc tgctagaaga
    57421 ttctgcacca ttcatcactt ttaattgtgc acaatatgca gataatcctg aacttttgac
    57481 tagcaatttg tttggacatg ttaagggagc gtacactggt gcagaagaaa ataaaaaagg
    57541 ggcttttgaa gcagcagatg gtgggatctt gtttttagac gaggtacatc gcttaacacc
    57601 agaaggtcag gaaaaactgt tcacctatct tgatcaaggt gtgatttatc gtatgggaga
    57661 acctaatttg tcacgccgga tcaaaacacg tctctttttt gctacgactg aagagattac
    57721 tagtcatttc ttaacaactt tcattcgaag aatacctatc cgaatcgaac tacctgcact
    57781 taatcagcgt agtcgtaatg aacggctaga actgatttac tctttttttc tcgaagaaca
    57841 aagaaaaatg gggagccctt tgtcagtcag tggaccagct ttgtcacttt taacaagtca
    57901 gaaattatcc ggaaacatag gagagctgaa aaatatcgtc aaagtttcag cagcaaaagc
    57961 atatgctgaa cagcgtgaac agcctgaaat ccatgtcacg atccatcatt tgcaaaaaga
    58021 actacttgcg cagcctatta ctaaaaatac agcacagcaa ggaatctata ttacgcaaga
    58081 ccagacctta gagcaattaa tggagaagca acagcccgaa cagcagcgaa tcgttaaaag
    58141 ttttgagcaa atcctaattg atttcaagaa aaataactgt ctgctatatt cttgcgaagg
    58201 aaaattaaag caagaagtga ttcaattatt tgattttttg ctgtttgaga ccagtagaca
    58261 agaaaaacac gagctgctgg tttattggac acaatctatc cgagagacct ttcgacaaat
    58321 ggaaactgcc tatcaaatca aattcgatgg aaacagtgtc tatgccttga gttactatct
    58381 ctatcagcga agcactatca aatggttacc ggaagaacat gatattatcc aactaatcaa
    58441 agaattagaa caacaagttt ctcagtctta tccatctagt tatcactatg tccaacgaat
    58501 tctggaatta agtaagatca aattagatat tgaagacaca agtatggatc ggattttact
    58561 gacgatctat ctaaaaaaag cgaaatggtc aaaagaaaaa cgactgccaa aagcgatgat
    58621 tgctgctcac ggttatgcaa ctgctagcag tatggcaaat gtagtaaatc gtttattaca
    58681 agaggatcta tttgaatcat ttgatatgcc actagatgtc acaccacagc agattgcttc
    58741 agaaatcctt gattattgcg aaaacagcga tgtttcaaat ggattgatca tattagtaga
    58801 catgggatct ctgaaagaaa tccatcagtt ttttaaaaaa cagttatccg taccgctttt
    58861 gattttgaat aatgtgacga cacctttagc aatcacagta ggggaatgcc tgcaaaaaaa
    58921 tgtatcatta gaagagatag cagaagagac tgttcgacag atccagccag aatggcgact
    58981 gctctatcca gaggaaaaca aacccaaagc actcattact acttgcttca ctggaatcgg
    59041 tacggcggtc cacttaagtg aactgctaga aaaaagctta cctacggctt gtcagttgaa
    59101 aatcatccca tatgaatatc agcaattaaa agataagaaa aacagtgacc cattattttc
    59161 catatacgaa gtcgtaggaa tgattggcac cacagatcct gatatcacca atatcgacta
    59221 tctttcatta gaagacctca tctcggggga aaagatgtct gtactagctg aatggttgga
    59281 cactactatg aatgcttcag agaaggaaat attcaatcag cgcatcattc gtaatttttc
    59341 attggaaaaa gtactggatt ccgtgactat tctagataca gagaaggtga tgggagaaat
    59401 cgatcatttt atgagagaat tagaggtgca gttgaatcga agcatcagca atcccaaaaa
    59461 attagcgttg tatgtccatg tgagctgtct cattgaacga ttgatccgac aaatgccaat
    59521 cgaaacctat caaggattag agaaatggaa gcagtgtcaa aaagaagggt tatctgctat
    59581 taaatctgcg tttagtgtca ttgaagagca ttatagtgtc atgatcccca attctgagat
    59641 tgcctatatc tatgatattt tgagtgaaga tacagagttt ctctcgatag aagaagaatt
    59701 ttgaacataa gcaagttgtt gccactaatt ttggcatgca acttgctttt ttagtatgtg
    59761 taagtgaaaa gaggagatga aaaagtggat agagaaatta tcttagcttc ccatggaaaa
    59821 tttgcttcag ggatattaga ttcattagag ctgatctatg ggaaaaatca ttctattact
    59881 gtattcgatt gctatactga tgagaatttt gatttagcgg aaacagtaag gcagcttttt
    59941 atgaggtaca aagataaaga aatcattgtt ctgacggatc tttttggcgg aagtgtcaac
    60001 aacgaattct tacaatatat caatcgggat catgtctatc tcgttgccgg attgaatttg
    60061 ccactattga ttgagctagt atctcggttg gacgctgaag tagagacaac tgttttgatc
    60121 cagcaggtgc taactgattc aaaaaaaatg atccagtttt gtaacgagcg gctcaatcag
    60181 aaaatagaag aagacgaatt ttaggaggaa gaaaaatgat tgtattgaca agagtcgacc
    60241 atcggttatt acacggacaa gtagcttttt catggacaca aacaataggc gcagactgta
    60301 ttttgattgc taatgatgat gtacctacga atgagatacg aaagacaacg atcaaattag
    60361 ccaagccaca aggagtcaaa ctagtgatca aatcaattga tgactcgatt gccgcgttga
    60421 aaagcggggt gacagataaa tataagttat tcatcgtagt ggaatcgatc gaggatgcat
    60481 ataagctggc agaagcgtat ccagaaatca aaaccatcaa cttaggaggg atcaaggcaa
    60541 aacctggtac tcgcagcatc ggaaaagcgg taaatatttt accagaagag gaggaacgct
    60601 tgaaacgatt aattgacaaa caaatagaag tagaaatccg tcaagtacca gcagataaaa
    60661 aagtggatgt aagagaagtt ttgtaagaaa ggaagaacct caatgattgt acaagcagtc
    60721 ttattaggaa ttgttgcatt tgtcgcacaa tcagaatatg cactagggac atcgttgctt
    60781 tctcgtccga ttgtgacggg gctgtttaca ggaatcgtgt taggtgatgt aaaaactggg
    60841 atcattatgg gcgcaacttt agagttagca tttatcggat cgttctcagt aggtgcttcg
    60901 attccacctg atgttgtgac cggtgggatt ttagggacgg cttttgctat tacagctgga
    60961 gccggtacag aaaccgcgct tttactaggt ttgccgattg ctacgttgac attgatattg
    61021 aaaaatattt acttagggct tttgattcca attatgaacc ataaagcaga caattatgca
    61081 gaagaaggaa attataaagg agtcgagcat atgcacttgc ttgccggtat cggtctttcc
    61141 ttgatgcttg gtgttgtggt aatggtttct tatatggtgg gaagcaatac gatcggaaat
    61201 ctattaaata tgattcctga cttcgttcaa aaggggttgt cagtagctac agggttgatt
    61261 ccagctcttg gttttgcgat gcttgctcgt ttgctgatca acaaacaagt tgcaccatat
    61321 tttttcttag gttttgctat agcttcttac ttagagattc ctgtgaccgg agtagctatt
    61381 tttggtgcga ttttagcagt tgtggtagtc aatattatga atgtccgtca actaccactt
    61441 caaacaactg caggggaggt agaagaagat gaagaattct gagatcaaaa acagcaaaat
    61501 aacgaaaaaa gagctaaatc acgtattttg gcgttctttt caaatggagt tttcttggaa
    61561 ttatgaacgt cagatgaata tggcttatgt ttatgcaatg attccgattt tgaaaaagtt
    61621 atatcagtcg aaagaagaaa tggcagcagc tttgaaacgg catctagagt tttttaacac
    61681 gaccccacat atcgttacac tgattttagg aatcacggct gcaatggagg aagaaaataa
    61741 ggatgatcct gaatttgatg tgactgcgat cgatagtatc aaaacatctt tgatgggacc
    61801 tcttgcaggg ttaggagatt ctttcttttg gggaactttg cgattgattg ccacaggtgt
    61861 gggtacctct ttagccatgc aaggaaatat tttaggccct atcttgttca ttttgatttt
    61921 caatattccg cacattctgt ttcgctatct agcaacaggt tggggatatc gcttaggaac
    61981 gggttttttg aaaaagatcc aggcaaacgg tatgatggaa agtttgacat taggcgcgtc
    62041 tattattgga ctgatggtcg ttggagcaat gactgccacg atgatcacca tcaatattcc
    62101 tttaaaaatc ggttcaggag aaaatgctgt gactgttcaa agtatttttg atgatatcgt
    62161 tccaaatatc ttatgtcttg gagcatttgg catagtgttt tatctattga agaaagaagt
    62221 gaaaccatta acgatcttga tcggactagc tttctttgga atttttggtt cgtggatagg
    62281 gattttttaa aaaaggagca gagaaaatgt ttacgatgca agattatatc tatgaagaaa
    62341 aggaagtact aagtacgatc ttgaaaaaga atgatttttc gacaagagaa catatgaaaa
    62401 aaacagtgaa tttactgatc ttagcaacgg gttcatctta taacgcttgt ttagcagcga
    62461 agccagcatt ggaatcttat ggtgatctta ctgtcgatat tcaagaacct ttttattttt
    62521 tcaattatgg aaaactttct ccttcaatcg atactgtgat tgctgtgtca caaagcggga
    62581 aaagtgcttc tactgttgaa gcagtaaaaa tgatacaaaa acaagggtta cctgttgttg
    62641 ctatcacaaa tgacgtgcaa agtccacttg ctttagaagc tgcacaaatt attgatttag
    62701 gtgccggggt agaatcagta ggcttcgtta caaaaggcta ttctgcgact gttttacagt
    62761 tactactctt agggatagga attggaataa gtaaaaataa aatcagcaaa aaaatagaac
    62821 aagactacat acaacagttg cgcaaaataa tcaaccattt accagcgatt attcaaaaaa
    62881 cggaagaatt ttttgatgga tatcaaagtt tatttcgttt agcacagcgt ttcgtcacca
    62941 ttggatatgg tccaaactgg ggaacagcta aagaagcaga gacgaaattg actgaaacaa
    63001 tccgcgttcc gtcacaagga tttgagttag aagcttatat gcacggccca tacctggagg
    63061 cagatgcttc gcatttgcta ttctttattg aaggggaaag tgtaaataag gaacgttcgc
    63121 aaaagttgca aagatatatg agtcggtacg ttggagagac tctcaccatt accacaaaaa
    63181 aagcaagaaa cgagaaaaca cttggattag caatagaatg tgatgaatat ctgtctgtat
    63241 tagcgcttgt cgttccgttt caactattcg cttataaaac cgcagtagct aaaggtattg
    63301 acttgaacaa aaagattttt gaagactttg atacagtctt gaaaagtaaa ttataagagg
    63361 tggaaatcat gctgaaattc aatgaagaag aacaaatcaa agcaataaaa ggcgcactag
    63421 ctttacgtcc gcaagtagaa gaaatcatcg ataaacttta tgcggaaaaa tttgacgctg
    63481 tctattatct aggaatcggt ggaacgtatg cttcctcgat gcaagctgtc acttatatga
    63541 atgggaaaag caacttgcct gtctttgtac agcatgctgc agaatattac actactggaa
    63601 acaaaagatt aacaaaagat tctatcgtta ttttgtcctc tgttaccggt acaactcaag
    63661 aagtagtgaa agcagtagaa caaatcaaga aagtaggagc gacactgatt ggatttatcg
    63721 ataaagcgaa cagtaagttg tctcagctat gcgattttgt ggtcacttat ccagctcctg
    63781 gaacagaaca aatcaaattt tttatggcag cagatcgatt gatgtatttg aatggagaat
    63841 tcgaagctta ttcagaatac tatgaacagc tcgaacgtta tttaccaaca gggttagtgg
    63901 aagcagagaa aaaagcagat gcatttggct tatcatttgc agaaaaacat cgacgtgata
    63961 gtatgcatta ttttattgga gcagggaatc aatggggagc tgtttattca tatgccatgt
    64021 gttactggga agaacaaagc tggcttccat cgaaatctat ccatgctgcc gagtttcttc
    64081 acgggacgtt agagatcgta gaagaaacaa ccccagtcac attattttta ggcgaagatg
    64141 aacagagagt gttatctgaa cgtgtggcta aacttttgcc aaaaatttgc agcaattata
    64201 cattgataga cacaaaagac tatccagtag aaggtatcag tgaaaaatat cgcggacgtg
    64261 ttttgtcttt cttattgatg catgtagtga cacaacgcat cgatgctcat gtggagcagt
    64321 tgaactgcca tccattagag atacgccgct actatcgtca gtttgattat taggatagac
    64381 tggataaaaa gaatataaaa aataaagaga gcagcgataa ctgctccctt tattttttta
    64441 aaatattggc atcaattacg ttataaaaca cattttttgc attatctaca gttcaactta
    64501 taatctgttt aatgggacat gtgggtgcca accatttttt gttatgcaat agtactattt
    64561 agttgttgca tggatccgta gtaaaagtcc aagtacaacg agttgcgcca gtttacatag
    64621 cgttttgtat ccagaatgtt gactaaaaca aaagttccta tgtcaaccgt caacagagac
    64681 aatctgtccg ttgcaggacc tgacagattt agaaatgttc aatctgtctc ttatgtattt
    64741 taaatcaata ctcactagga gaagtttcct aacctcctaa tagtaatgct ggtagtaaca
    64801 ttgtcaaaac tgcttcctct taggaacaag caaagcataa cgagtgtaaa aataaaatgt
    64861 agactattgt aacatatcat tgattatttc aagtaaaaac gataaaagaa gtaaacaaac
    64921 acttaaaaac aatggaaatt agtcccaact ttaagaaatg tatactataa tggaaattat
    64981 caattattta tttggaggaa tatccatgaa acaaaaaatc gcagttcttg gtcctggatc
    65041 ttggggcact gctttagcac aaacattggc agaaaacggg catgatgtcc gtatttgggg
    65101 aaatgtacct gaacagattg atgaaatcaa taagtatcat acaaatcagc attttttacc
    65161 tgatttgacg atcccagaat cgattatcgg atataaagaa ttggcagaag cagtggataa
    65221 cgcagatgct attttatttg ttgttccaac aaaagcgatt cgttcagtcg cacaggaact
    65281 tattggtaaa atgaatacta agccaatcat tatacatgca agtaaaggac tagaacaaga
    65341 tacgcataaa cgaatctcag aagttttggc tgaagaaatt ccagaagaaa aaagacaggc
    65401 aattgttgta ttatctggtc ctagccatgc tgaggaagtg gcagtacatg atatcacaac
    65461 aattacagct gcaagtattg atcaaaaagc agcagcctat gtacaaaaac tgttcatgaa
    65521 tgattatttc aggatttata caaataatga tgtgattggc gtagaaactg gtgcagcact
    65581 gaaaaatatc attgcaattg gtgccggcgc tatccatgga ttaggattcg gagatgatgc
    65641 aaaagcagca atcatgactc gaggattggc agaaatcagc cgtcttggtg tcgcgatggg
    65701 tgccaatcct ctgacattta tcggtttgag tggtgtgggg gacttgatcg ttacttgtac
    65761 aagtgttcat tctcgcaatt ggcgtgccgg taacttgtta ggacagggac ataagctgga
    65821 agaagttcta gaaaacatgg gaatggtcgt tgagggtgtg gcaacgacaa aagcagcagt
    65881 agagctagct caacagctag gtgttgagat gccaattact caaacaatct ataatgtttt
    65941 gtataatgga gaagatatca aaaaagcagc aaaagaaatc atgttacgtg acggaaaaat
    66001 ggagaatgaa ttttctcttc gttaaataga tgatcaatag ttaatcgt
//
LOCUS       DASHWW010000009        61138 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.009, whole genome shotgun sequence.
ACCESSION   DASHWW010000009 DASHWW010000000
VERSION     DASHWW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.009"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(500..943)
                     /locus_tag="U2R64_000698"
     CDS             complement(500..943)
                     /locus_tag="U2R64_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEM8917540.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(1161..2501)
                     /locus_tag="U2R64_000699"
     CDS             complement(1161..2501)
                     /locus_tag="U2R64_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8917541.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2770..3666
                     /locus_tag="U2R64_000700"
     CDS             2770..3666
                     /locus_tag="U2R64_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEM8917542.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3816..4757)
                     /locus_tag="U2R64_000701"
     CDS             complement(3816..4757)
                     /locus_tag="U2R64_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEM8917543.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4883..6004
                     /locus_tag="U2R64_000702"
     CDS             4883..6004
                     /locus_tag="U2R64_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEM8917544.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            6262..7764
                     /gene="eat(A)"
                     /locus_tag="U2R64_000703"
     CDS             6262..7764
                     /gene="eat(A)"
                     /locus_tag="U2R64_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEM8917545.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7792..8358
                     /locus_tag="U2R64_000704"
     CDS             7792..8358
                     /locus_tag="U2R64_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8917546.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8569..9630
                     /locus_tag="U2R64_000705"
     CDS             8569..9630
                     /locus_tag="U2R64_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEM8917547.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9633..10529
                     /gene="murQ"
                     /locus_tag="U2R64_000706"
     CDS             9633..10529
                     /gene="murQ"
                     /locus_tag="U2R64_000706"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEM8917548.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10543..12525
                     /locus_tag="U2R64_000707"
     CDS             10543..12525
                     /locus_tag="U2R64_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8917549.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12590..13036)
                     /gene="nrdI"
                     /locus_tag="U2R64_000708"
     CDS             complement(12590..13036)
                     /gene="nrdI"
                     /locus_tag="U2R64_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEM8917550.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            13247..14671
                     /locus_tag="U2R64_000709"
     CDS             13247..14671
                     /locus_tag="U2R64_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8917551.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14852..15625)
                     /locus_tag="U2R64_000710"
     CDS             complement(14852..15625)
                     /locus_tag="U2R64_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8917552.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15622..16527)
                     /locus_tag="U2R64_000711"
     CDS             complement(15622..16527)
                     /locus_tag="U2R64_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8917553.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16681..17001)
                     /locus_tag="U2R64_000712"
     CDS             complement(16681..17001)
                     /locus_tag="U2R64_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEM8917554.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17475..18161
                     /locus_tag="U2R64_000713"
     CDS             17475..18161
                     /locus_tag="U2R64_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEM8917555.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18163..19107
                     /locus_tag="U2R64_000714"
     CDS             18163..19107
                     /locus_tag="U2R64_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEM8917556.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            19306..19950
                     /gene="pcp"
                     /locus_tag="U2R64_000715"
     CDS             19306..19950
                     /gene="pcp"
                     /locus_tag="U2R64_000715"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEM8917557.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            20029..21306
                     /locus_tag="U2R64_000716"
     CDS             20029..21306
                     /locus_tag="U2R64_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917558.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(21490..22239)
                     /locus_tag="U2R64_000717"
     CDS             complement(21490..22239)
                     /locus_tag="U2R64_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEM8917559.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            22569..22949
                     /locus_tag="U2R64_000718"
     CDS             22569..22949
                     /locus_tag="U2R64_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8917560.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            23045..23554
                     /locus_tag="U2R64_000719"
     CDS             23045..23554
                     /locus_tag="U2R64_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917561.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            23631..23810
                     /locus_tag="U2R64_000720"
     CDS             23631..23810
                     /locus_tag="U2R64_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917562.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            23835..24428
                     /locus_tag="U2R64_000721"
     CDS             23835..24428
                     /locus_tag="U2R64_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917563.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(24475..24990)
                     /locus_tag="U2R64_000722"
     CDS             complement(24475..24990)
                     /locus_tag="U2R64_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917564.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(25016..25885)
                     /locus_tag="U2R64_000723"
     CDS             complement(25016..25885)
                     /locus_tag="U2R64_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8917565.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            26011..26691
                     /locus_tag="U2R64_000724"
     CDS             26011..26691
                     /locus_tag="U2R64_000724"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEM8917566.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            26844..27824
                     /gene="pta"
                     /locus_tag="U2R64_000725"
     CDS             26844..27824
                     /gene="pta"
                     /locus_tag="U2R64_000725"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEM8917567.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            27947..28420
                     /gene="tsaE"
                     /locus_tag="U2R64_000726"
     CDS             27947..28420
                     /gene="tsaE"
                     /locus_tag="U2R64_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEM8917568.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            28413..28937
                     /locus_tag="U2R64_000727"
     CDS             28413..28937
                     /locus_tag="U2R64_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917569.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(29427..29960)
                     /locus_tag="U2R64_000728"
     CDS             complement(29427..29960)
                     /locus_tag="U2R64_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HEM8917570.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(30824..31576)
                     /gene="xth"
                     /locus_tag="U2R64_000729"
     CDS             complement(30824..31576)
                     /gene="xth"
                     /locus_tag="U2R64_000729"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEM8917571.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            31689..32609
                     /locus_tag="U2R64_000730"
     CDS             31689..32609
                     /locus_tag="U2R64_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8917572.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            32682..33617
                     /gene="murB"
                     /locus_tag="U2R64_000731"
     CDS             32682..33617
                     /gene="murB"
                     /locus_tag="U2R64_000731"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEM8917573.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            33915..35393
                     /locus_tag="U2R64_000732"
     CDS             33915..35393
                     /locus_tag="U2R64_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917574.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            35670..37730
                     /locus_tag="U2R64_000733"
     CDS             35670..37730
                     /locus_tag="U2R64_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEM8917575.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            37813..38382
                     /locus_tag="U2R64_000734"
     CDS             37813..38382
                     /locus_tag="U2R64_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917576.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(38557..39363)
                     /locus_tag="U2R64_000735"
     CDS             complement(38557..39363)
                     /locus_tag="U2R64_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917577.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            39501..41015
                     /locus_tag="U2R64_000736"
     CDS             39501..41015
                     /locus_tag="U2R64_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HEM8917578.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(41418..42401)
                     /locus_tag="U2R64_000737"
                     /pseudo
     CDS             complement(41418..42401)
                     /locus_tag="U2R64_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(42406..43053)
                     /locus_tag="U2R64_000738"
     CDS             complement(42406..43053)
                     /locus_tag="U2R64_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8917579.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(43138..43770)
                     /locus_tag="U2R64_000739"
     CDS             complement(43138..43770)
                     /locus_tag="U2R64_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8917580.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(43786..44337)
                     /gene="coaC"
                     /locus_tag="U2R64_000740"
     CDS             complement(43786..44337)
                     /gene="coaC"
                     /locus_tag="U2R64_000740"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEM8917581.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(44334..45071)
                     /locus_tag="U2R64_000741"
     CDS             complement(44334..45071)
                     /locus_tag="U2R64_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEM8917582.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(45068..46057)
                     /locus_tag="U2R64_000742"
     CDS             complement(45068..46057)
                     /locus_tag="U2R64_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEM8917583.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            46315..46857
                     /locus_tag="U2R64_000743"
     CDS             46315..46857
                     /locus_tag="U2R64_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8917584.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            46874..47959
                     /locus_tag="U2R64_000744"
     CDS             46874..47959
                     /locus_tag="U2R64_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917585.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            47971..48777
                     /locus_tag="U2R64_000745"
     CDS             47971..48777
                     /locus_tag="U2R64_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917586.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            48778..49605
                     /locus_tag="U2R64_000746"
     CDS             48778..49605
                     /locus_tag="U2R64_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917587.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            49602..50675
                     /locus_tag="U2R64_000747"
     CDS             49602..50675
                     /locus_tag="U2R64_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8917588.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            51103..53799
                     /locus_tag="U2R64_000748"
     CDS             51103..53799
                     /locus_tag="U2R64_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8917589.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            53876..54364
                     /locus_tag="U2R64_000749"
     CDS             53876..54364
                     /locus_tag="U2R64_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8917590.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            54376..54870
                     /locus_tag="U2R64_000750"
     CDS             54376..54870
                     /locus_tag="U2R64_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8917591.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            54891..55700
                     /locus_tag="U2R64_000751"
     CDS             54891..55700
                     /locus_tag="U2R64_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8917592.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            55697..56518
                     /locus_tag="U2R64_000752"
     CDS             55697..56518
                     /locus_tag="U2R64_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8917593.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            56569..58668
                     /locus_tag="U2R64_000753"
     CDS             56569..58668
                     /locus_tag="U2R64_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HEM8917594.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            58665..59783
                     /locus_tag="U2R64_000754"
     CDS             58665..59783
                     /locus_tag="U2R64_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HEM8917595.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            59822..60700
                     /locus_tag="U2R64_000755"
     CDS             59822..60700
                     /locus_tag="U2R64_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8917596.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            60846..61043
                     /locus_tag="U2R64_000756"
     CDS             60846..61043
                     /locus_tag="U2R64_000756"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEM8917597.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
BASE COUNT        19759 a        10754 c        12662 g        17963 t
ORIGIN      
        1 ataaaaaggg attgtgacaa gacttttgtc acaatccctt ttacgaataa acggtattca
       61 aaagccagtt tctcggtatt aagccaaatt tatacaaaaa tgtggaaagc catttcacaa
      121 aatttttctt aatacgcgaa actaagcgac tttttcacaa cctctcgata aacggtgttc
      181 aatcagctga ccctcggtat tagctcaaaa aatggcaaaa tatgaggaac tatttttcca
      241 tttgtctctc taatactcag gtcagaacgc tgattttaca acctcttaat aaacggtgtt
      301 caaaagcttg catctgcggt aataagccta accaaacgaa aaataggaga agctattttt
      361 gtttggctgt tcttattact tgatgcaggg cagctttttc acaacccctt attcacggcg
      421 ttccagaagt agcttcttct tatttcttga agctgataac ttctggaaca tcctcttttt
      481 ttatttggac ggataatggt cattccattt ctttgatcat ttttttcatt ttgtcgatct
      541 cttcttcttg tgcctgaatg atttcttccg ctaatttttt tacttcagga tcttttaaat
      601 cagctcgttt acttgccagg atagcgatag aatgatgagg aatcatggcc ttcatccaag
      661 ctgtgtcgtt gacagtagtt tggcttcgta ccataaacaa ggaaccggca aaaacaagaa
      721 gactagcggc taagatcata acatttatct ttttgttttc atacattttc cacatgaaca
      781 acagcatgat gactgccatg actgcaccca tcatcaacgc catgaatact cgtgtacgac
      841 tgaagaagat atgatcgagc gcatagacat tcaagtacat cataccaaac ataactaccg
      901 ttgaaacacc gatcatcaac aaaaacttcc aatacttttt catttaaaac aaactccttt
      961 ttttcattcc tttcttctat catgtcatga gcatggagaa caatcaatta ttttgcacag
     1021 agggtttttg aacaccgttt accaagaggt catgagactg tttattcgga aaaaggagtt
     1081 gcaacaagac ttttgtcaca actcctttct tcaatagctc catctattcc acataaataa
     1141 aataaaattt tctatcgatt tcattcattc gtcaatacga acgcatcatt ctttttttga
     1201 taactgaaat aaatgaacag gtaaagcagg ccagtcaata cagttacccc aatggagttc
     1261 gtgaacagga taccaaggaa aatcaatcct aagacagcta atgcaaaaaa gctgattcct
     1321 ttatcccata atgttccttt tcttagtgcc agtacaaagg atgccgcact gataatgatc
     1381 cagatcaata atactgtata cgaaagggaa cctgccagat agccaaataa tttgtcaccg
     1441 acaaaataag aaagagctac accaagataa agaacactgg tacaaaataa aacagcacgt
     1501 tgcggtactt gatgcttgtt taaaacagct agttttctag aggaaccttt tcgatccttc
     1561 aaacggaaga acaaaattct tgaagatgca tacacacccg aattgataga tgagaacaaa
     1621 gcaaggacaa tcacaaaatt gacgatatcc gctgcaaatg ggatattcat tttttcaaat
     1681 accatcacaa aaggactgac attcgtgcct gctaaagtat tccaaggaaa aagaatcaaa
     1741 agcaaaaaca aaggaatgat gtaaaaggaa atgattcttc ccatgacacc tttgattgct
     1801 ttaggaatcg cacgtttagg atcatctgct tcgcttaccg tgatagcaat cagttcagaa
     1861 ccgccgtaag aatagataac tacaagcaaa gaactgatga ttcccttcat accatgagga
     1921 gtaaacccac catggtcagt caattgctga agggtaggga aaacgcctgt gcccaacatt
     1981 tgctgaccga caagataagt agcaaaaatg atcagtaaga taatgacact gattttagca
     2041 aaagccagcc aatattctgt ttctgcgaat aaccgtaccg aataaagatt gatgatcgta
     2101 gttaaaacag ccaacataaa aacaaatacc caggctggaa tgtgcgggaa ccacaactgc
     2161 aaaaaggaag cagctgcaac agcttcagcg atgatattga taatccacat agaccagtag
     2221 acccaatcag taaaatcagc agaatgagca cctagataag ggcgtatcaa accagataat
     2281 ccgtgatgcg tgtcgccacc gcttaaaacg atttttccca gacctttcat cacgatatat
     2341 aaaatcagcc caccaatcaa aaaagcaatc aatacagaag ggccggcgat cccaatcgct
     2401 tcgccacttc ctttaaatag acctgcaccg attgctccac ctaaagctaa catggtgata
     2461 tgtctggagc taagttgttt tttcaatttt ttatcttcca taaatgacct ctttctttta
     2521 aattcacaat caaaatttat attaagaata aatagcaata tttaacaatg actaatgata
     2581 acaaattttc agacaattac aactattcag aaaactttta ggcgaatttt aatagaagaa
     2641 tgatttattt catcatattt tcatacaaat gttaaatttt catacaaata taggaaacgt
     2701 tttactggct ttttactatt taaacaggct atcataggaa aaagtgacag agaaagtgag
     2761 gcggaaaaga tgaacaaaaa tgacgtactg ctagttgcaa aaaataaatc actttatttt
     2821 ttgccttcca tccgctcttt agatgtttgg tccggaaaag atttactaca gtcggaattc
     2881 attaaatcag ctagacaaca gttggcaaat tatcagctga tcgttttttt agattatgga
     2941 tttgatatgg agatggctcg acgcgtgcgc ccatttacca atgcaaaaat tgtgttattt
     3001 ttttggaatc acttcaaagc agaacacgag gcgatgctga agcaggcaca agatgaaccg
     3061 gcaatcgatg agatttatca ttttgatttt ttggaagcaa aagaacttgg gctgaaacat
     3121 aatagttcat tttattcgaa acatatgaat ttttcttcta gcgaaccaaa gacggatcta
     3181 ttttttggtg caacgaataa tgggagaaaa gaacgagcag aaagctataa gcaggaattt
     3241 ataaaaagag atgttacgac caactatttc attcttccac atcgagggaa tgaacaacct
     3301 ggatatctta cttatgaaga gtacctgaaa aaaacagggg aatcgcgcgg gattctggaa
     3361 ctgttgcggg agggtcagca aggagtgact ttgcggacat ttgaatccat gtattttcaa
     3421 aagaaactag tgacggataa tcaagcgatt gctcattatc atttttatcg tcctgaaaat
     3481 atttttttgc ttcgagaacg tgatttagat gaattaccgg aatttctgca tacaccattt
     3541 aagccaatcc tatcagagct attggaattt tatgatgcag aaaattgggc aaaacgattt
     3601 atcactaacg attccactat ttatgagcaa tacgaatatg acctctcctc tgttgaaaac
     3661 aaataaaaaa cctacatttt gaagagatta tgtactgaaa caaacaagca caattcttat
     3721 ggcatcatga gagttgtgtt ttctttttga tcttttattg ggcttaaaaa aagagaacca
     3781 gctgctgatt cagctgattc tcatcagaga gccttttatt ctgcgccaag gattccttct
     3841 tttgcatgga ctaattgggt caaaaaggca caatatggtg tagcaatatc atatttttgt
     3901 ccttttcgcc aaatggcacc attgatgtag tcgatttcag tcaaacgatg gtttttgatc
     3961 aggtcttggt acatagatgg gtaatgcaac ccgatgttgt caggatcata agtagaagca
     4021 atatgttggt acacttcttc ttgatctagt atgattcctt cttttgctgc gatagaagca
     4081 aattcagata cgattgttcg aaccatgctc tctgccgctt tttgcgcgcc tagttcagca
     4141 atattacaat ccaaaatcgt gcataaacca ttcaatgttc catttacaca agcttttcgc
     4201 caaatggaat aacgaacgtt atggctatag atcggattta aatttgcttc ttgaaagact
     4261 tctacaactt tttttgtaaa tgcttcgcct tctggttcca agttctctag ttcgatttct
     4321 ccatcaccta acaatgtgac ttttccggga ccagctagac cagctgtcca catcgtgatc
     4381 ccaaataaga tatttttctt tggcacatat ttttccagta catcttcatg acctaatcca
     4441 tttagtaaac acaaaacata agtattgtca gtaataatgg attggatcga acaaaacata
     4501 tcatctaatt gattggcttt tgttaatgct acgatcaagt ccacgtgttc gttgctttcg
     4561 atgatttctt ctggtgaata gattggcagt tttgcgacca cttctttacc gttaaagtca
     4621 gcaatcaacc catttgtacg aatggcttca atgtgagcag gccaacgatc gatcaagagg
     4681 acctcatttc cgctttgatg tagcatcaat ccgattcggc tgcccattgc tccggcccca
     4741 gctattgcga ttttcatgtt ttttctctcc tttattcaat gagttccctt ttagtatata
     4801 gaaaaatgga agaaaatagc attgttttgt ttgaaaaaaa tgaaaaaaag tgtcttactt
     4861 aagaagaaag tgagggatac agatggatat tttggcggca attgattcat ttaaaggaag
     4921 tgcttcttca tttgaactaa atcaggcagt tctaaatggc tgggaagatc gtaaaggaag
     4981 aaaaatcaat gtgccgattg cagatggcgg agaaaatact gcagaagcaa tctattacgc
     5041 gctcagggga acatggcgta ccattgatgg gatggatctc ttattccgtc agcgaaaaat
     5101 cagctattta ttgacaactt ggcaaggaaa aaacaccgca gtcatcgaat ctgcacaagc
     5161 attggggtta gatctacttg ataaaccaac ggatcaaact atccgacttg cttccagtta
     5221 tgccttagga gaacttatta aagatgcact gcttcaagaa gtagaacaaa ttattgtcac
     5281 tttaggagga agcgggtgta gcgatggtgg tctaggatta ctccaatcct tgggtgcttc
     5341 tttagaaggg tacacagaag gaaatccttt attatctact aaaaaacttc attttgatcg
     5401 aagaaacgtt cttgtttcta aagtaaaatt gattatcgct gcagatgtta ccaatccata
     5461 tacaggtcaa caaggagctg cttggcaatt tggaagacaa aaaggaggaa tagatacgac
     5521 gctagctttc ttagataaac aagcaggaaa gattgctcag caaataaaag atttctggga
     5581 ggtggattta gatgatattc caggaagtgg agcagcaggc ggtattggtg gagccctttt
     5641 tttgttggga gcgaagatgg tttctggttt cgatttagtc agccaaatca ctggattgga
     5701 aaaaaagatc gaacaagcag atgtcatcat tacaggagaa gggcggatcg atcagcaaac
     5761 gatccacgga aaagttccat acggtgtagc agtgcttgca aaaaaatatc gaaaaccaat
     5821 aatcgctatt tgcggaagta gagaccaaga gctagaagga ctttctgatt ttctcccaat
     5881 tgtcttaagt attcatttgg gtccaatagg tttagaagaa gcaatggaac acaggcaaac
     5941 attagaaaaa acaaaaatct taggacagac acttagcaga tttttcacca tcctcccgaa
     6001 gtagttgaca aaatcatttt ctttatgcta tcgtaatttc aaatatagga caaagtgagg
     6061 gatccgtgca ttgaaaaatt aagtcgattg atgaaagctg cattcagact gtaccttgtg
     6121 gagacaagga agcagtgtgc agattttcgg gattggcttg gttttttcga tgtatgggtc
     6181 tttttgtgtg tatccaaccc ttgcatcctc tttagccagt tctgaaaata ggactggtct
     6241 ttttttacga ggtgatggaa aatgtctaaa atcgaaataa aaaatctgac attcggctac
     6301 gacagccaag gcacattatt atttgaacaa gcaaatctaa attttgacac acaatggaaa
     6361 ctaggactta tcggacgaaa cggtcgagga aagacaactt tactgaatat tctacaaaac
     6421 aaactacctt atcaagggca agtaatccat cagcaagaat ttgcctattt cccgcaacag
     6481 acaaaagata aagaacgttt aacctattac gtgttaaatg atattacgga ttttgagata
     6541 tgggaaatcg aaagagagct ccaattgatg caaacagatc ctgaaatctt atggagagaa
     6601 ttcagcacac tatcgggggg agagaagaca aaagtcctac tggcactttt atttgtggat
     6661 gacactcatt tcccgttaat cgatgaacca acgaatcatt tggatatctc tggtagaaaa
     6721 caagtagcgg cttatttgaa aaagaaaaaa caaggcttca tcgtggtcag ccatgaccgg
     6781 ggatttatcg atgaagtagt ggaccatgtt ttagcaatcg aaaaaagtca actggaactt
     6841 tatcaaggga atttctctat ctatgaagaa cagaaaaaac ttcgtgatga atttgaaatg
     6901 gctcaaaatg aaaaattgaa aaaagaagtc agtaggctaa agaaaacagc agctgaaaaa
     6961 gccgaatggt ctcgttcccg agaaggagat aaaacaaaga aacaagtcgg attcatcgat
     7021 actgaatcta gacgagtgaa taaaggagca gtgggtgctg atgctgcacg gacgatgaaa
     7081 cgatccaaag caatcgtgaa tcggatggag acccagatca gcgagaaaga aaaactatta
     7141 aaagatatcg aatatatcga ttctttgacg atgaatagcc aagcgtctca ccataagcga
     7201 cttttaagcg tagaagatct tcaattaggg tatgaaaatc tgttattcga gccaattcat
     7261 tttacaatcg agcctcatca gcgggtggcg atttcaggtc ctaacggtgc aggaaagtca
     7321 tccattatcc attatcttct gggggcattc aacggcaagg ttataggaga aaaataccag
     7381 ccaaaacatc tgagcattag ttatgcaagc caaaattatg aagacaatcg aggaacgttg
     7441 gcggaatttg cagagaaaaa ccaagtagac taccaagcat ttttgaacaa cctccgaaag
     7501 cttgggatgg aaagagatgt ttttcataac aagatcgagc agatgagtat gggccaacgg
     7561 aaaaaagtgg aattggctaa atctttatca cagccagctg aactatatac atgggatgaa
     7621 ccattgaatt atttggatgt cttcaatcaa gaacaattag aacaactgat cttgaacgtg
     7681 aaacctgcca tgttactagt ggaacatgat caaaccttcc tggataaagt atctactgag
     7741 attatttctc ttgagagaat ctaacccttg taatctcaag aacaacaagg tatggttaag
     7801 gggaactttg ccaacgaagg agagaatcac atgctttatg taacgagaca cggagaaaca
     7861 acttggaacg cacaaggatt agtttgcgga cgggcagatg tgccgctgac tgaaaaagga
     7921 cagatgcagg cacagaaact agcagaaaag gtagtagatt tgcctgttcc aatcacgaaa
     7981 atcatccatt cccctcttca acgagcaaga gatacagcac aagcagttgc tgatcgtctc
     8041 agcttgccgc tgaccgttga tgaacgattg gtagaaatgg attttgggga ttatgatgga
     8101 ctgccaagca aagatgagaa ctttcaaaaa gcacgtttag cgttcgctgt acgattccca
     8161 aatggggagt cagtcttaga tgtgtatgca cggatcgttc ctttattgaa agaatgcatc
     8221 gaagacgaag aaaatgtcta tctgttagtt tgccataatg ccttgataag agtgatcaat
     8281 gcttattttc atccgatgcc taatgagggg ttctttacat tcatggtaga taatacagaa
     8341 ttggtttctt atgagtaatt atgtttttgt gttatttaaa taaaatattt caaggcactg
     8401 cttttgctta gcagtgcctt ttttaggtta tgacaattct tttgataata taaactcaac
     8461 ctttagaaat gaaatttaat tattttaata aaagtattga aattttgttt ctttagatat
     8521 atactctagt catagaaatg aagacggata cagaaaaaga gggataatat gtttggcttt
     8581 tcaatattta tgaacgattc tttgtcagaa gagaagaaac agtatatccg ccaaatggca
     8641 tccaatggct ttgtcggtat tttcacttcc atgcatatac cagaagatga tgtttcggca
     8701 tatcaaaagc gattgatcga actaggaagc gaagcgaaaa agaataaact agaattgatg
     8761 gtcgatattt caggagaggc attggaacga gcgggttttt cattagaaga tctaacgcct
     8821 ttgaaagcaa ttggtgtaac aggtttaaga atggattatc atatttccaa tcagcagatt
     8881 gccgactggt cacatcaatt gaaaatcagt ttgaatgcta gcacgatcac gcctaaagat
     8941 atcgatgaat tgaaagaagc agaagctgat ttctcacaga ttgaagcttg gcataattat
     9001 tatccacgtc ccgaaacagg gctggacaaa gaatggtatc agaaaaaaaa tcaatggctc
     9061 aaaattcaag gtctccttgt ccaaggtttt gtaccaggag atacagagtt gagaggccca
     9121 ctatatcaag gattgccaac tttggaagaa catcgaggga tccatcctct tgcaggcgct
     9181 ctagatctat tagcaagtaa cacggatatt gtttacatcg gagatgcagg tctgtcagaa
     9241 aacgttcagg agcaatttgc ttctttccaa aaagaacaga cagtcttgct ccatacggaa
     9301 cctgtagatg aagaatttta cgaatatata ttagggaagc atacgaatcg gcaagacgat
     9361 gcaagagatg tcatacgaag cgtagatgca cgttttcgag agattccgcc tatcccagca
     9421 agaaatacag ctacgcgtat gaaagggtct attactttag ataacgaaaa gtatttgcgc
     9481 tatatgggtg agatccaatt aaccaaatat gatttgccag cggatgaaaa agtgaatgta
     9541 gtagctaaag ttatcaaaga agagctacca ttgatcaacc aaatcaaagc tggtatgaac
     9601 tatcaattta taagaaaaga aggaagataa aaatgagcaa aatcaattta gagaacctaa
     9661 caacggaacg cagaaaccaa gaaacttttg gattagatga gatgagtatt tctcaagccg
     9721 ttcaactaat gaacaaagaa gatcagaaag tggccgctgc ggttgaaaaa gaactgacaa
     9781 gtatcgaacc agtgattgct aacacgattg agtcctttaa aaaaggtgga cgtctgattt
     9841 atatgggagc cggaacaagt ggaagactag gtgtgttaga tgctgctgaa tgcgtaccga
     9901 cattcggtgt agaaccggaa atggtcatag gtctaattgc tggtggagaa gaagcaatga
     9961 ctgtagctgt cgaaggggcc gaagattctt atgagctagg gcaagaagat ctaatcaagc
    10021 tgaatttgac aaaaaatgat atagttattg gtatcgcagc tagcggtcgt acaccatatg
    10081 tgatcggtgg attagattac gcaaaatcga tcggtgctgt cacaggaacg atttcttgca
    10141 ataaacaagc cgaaatcagt aaacacgcgg atttcccaat cgaagtcgat gcaggtccag
    10201 aatttttgac aggctctact cgattgaagt caggaacagc acaaaaactt atcttgaata
    10261 tgatttctac tatcagtatg attggtatag gtaaagtatt caataacttg atggtcgatg
    10321 tcaaaccaac aaatgaaaaa ctaatcgaac gctcaaaacg aatcatcatg caagcgacag
    10381 aagctgatta cgaaacagct gaaaagtact ttgaagaagc agatcaaaat gttaagctgg
    10441 ctatcgtcat gattttgaca aatagtgata aagaggaagc tcaagcaaaa ttagctgaag
    10501 caaacggatt tgtaaaaggg accttatgag ggggaaaaga ccatggcaaa aaacgaactg
    10561 actttggaag aactggcaaa acaaatttat aaaggggcag gcggcatggg caatgtagaa
    10621 agcattgtcc actgcatgac tcgtgtgcgt atgaagatca tcaatgatga tcttgtaaat
    10681 gtctctgaat taaaagcgat tccaggagtg cttggtgtag tagaagatga acagcttcaa
    10741 gtcatcatcg gacctgggaa agtgaacaaa gtagcacagc aaatggttga tttggcaggc
    10801 gtgaaattag gagaaaaact ttcttctgta agtacagcta cagcaaattc atcagcatct
    10861 ggaaaagacc gtgtaaacga acgggcacaa gaaatgaaag cggcacaaaa atcgaaacaa
    10921 aaaccatcta aaatcaaatc ggtattaaaa gacatttcta atatctttgt gccaatgatt
    10981 cctgcatttg tcggtactgg gatcgtggca gggattgccg cagttttagc aaacttagtc
    11041 acagccggaa cacttgatgc agcaacatgg caacaatata tcgatgtgat gaacatcttg
    11101 aaaaacggga tgtttagcta cctagttatc tatacaggta tcaatgctgc acaagttttt
    11161 ggtgcaacac caactcttgg tggagttatc ggggccgttg tgatgctgac agggatgaat
    11221 ccggaagcac cactgaaaaa cttatttact ggtgaagctc ttgcagctgg acaaggtggg
    11281 atcctaggtg tcatcttcgc tgtttggcta ttgtcaatcg ttgagaaaaa actgcataaa
    11341 gtagtacctg atgcggtaga tatcatcgtt acaccaactc tttcgttgat tgccatcggt
    11401 ctgattgaaa ttttcttcat catgccttta gcaggtttca tttctgatgg catggtcggt
    11461 gggatcaact gggtacttgg cgttggtgga gcatttgccg gcttcgttct aggcacatta
    11521 ttcttgccga tggttatgtt cggactgcat caaattttga ctccaatcca tgtgcaaatg
    11581 attgatgaaa ctggtcgtac gctattgctt ccaattcttg cgatggctgg tgcaggacaa
    11641 gtgggtgcag cattggcatt atggattcgc tgcaaaaaag ataaagaatt aacagaaatg
    11701 atcaaaggag ctttaccagt cgggatccta ggaatcggcg aaccattgat ttacggagta
    11761 acattacctc taggacgccc atttattact gcttgtatcg gtggaggtat cggcggggca
    11821 gtgatcggaa tgatcggaaa tgtcggggct atcgctattg gaccttcagg agccgctttg
    11881 atcccattga tctctgacgg taaatggtta ggctacatcc ttggattatt ggcagcttat
    11941 gctggtggct tcgttgctac attcttcttc ggtattccta aagaccgttt agaaaaagaa
    12001 gaattagcga ctgaaacagc cacagtaaat gaagtgcctg aaaaagtagt acctcaaact
    12061 tcagctgaaa gtgtgactat cctctcatca gttgctgacg gaacagttgt ttctttagat
    12121 aaagcaagtg atccagtttt tgcacaaaag atgatgggtg aaggctactt tgtagaacca
    12181 gaaaacggac atatctattc tccagttact ggggtagtca gctctgtctt cccaacgaaa
    12241 cacgctattg ggatcacaac gccaaatggt ttagaaatct tgcttcatat gggaatcaac
    12301 acagttgact taggcggtac gccatttgat gtgaaagtaa cagaagggca gcaagtgaca
    12361 cctgatacgc ttgtagcaga agctgactta gaagcgatca aagcagcagg caaagaaaca
    12421 tccatgatcg tcttggtaac caatatggat cgtgtaaaaa actttgtctt ggaaaaaaca
    12481 ggtaaagcaa aagcaaaagc acctgtgatg gatgtcaaag cttaatatga tagaaacaat
    12541 agaaacgaaa gaagaaactg aaatctattt ttcagcttct tcttttttat tatttattgt
    12601 tttctgctaa aatctgataa attcgtgtca catcagatgg tgttccccgt aattcataat
    12661 ctgccaagaa aggaaagcca aatgtttgtg catattgttt ggctgttaga caatactgat
    12721 tattgaagtt tttatttccg ctaccgacta caccaagaca aagtttatga ttgtcttcat
    12781 gttccagata ttcacgcatc gtttcggtca agatttctgt atcaccgtta tctaaaccat
    12841 ttccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct ttcgtaaaat
    12901 cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct tctgcatgca
    12961 ttttttcagc atattctgct agatgtttgg caaaggcacg cgtatttcct gaaatcgata
    13021 tatataaaat gttcatggat catcctccaa ttctttcctt ttagtatagc atctttttta
    13081 agttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata atgagaaaaa
    13141 agccggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat aaaaaaggtt
    13201 tgttatactt tttgataaaa gcggttttat tttggaggat gcttacatgg atacagagca
    13261 acagaaaaaa ggaattggtt taattccact tgctgcctta gtaattggtt cagcgattgg
    13321 aggtggcgta tttggtatta tgacggacat ctccggatcg gctggcggcc cagctatttt
    13381 cagttgggta ctcgtaggaa cagcaatgtt gatgctctcc ttgtcgatca ataatatcaa
    13441 taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag gttttggccg
    13501 tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag gcaacgtagc
    13561 ttttgcaaca ttgttgatga gcgcattagg atatttcttc ccagtatttg aaggtgggca
    13621 aaatctggca tcgatcgtga tgagtacagt ctttttatgg ggatatgcat ggctagtgaa
    13681 tcggggagtc gaaaatgcta gtttcgtcaa tgctatcgtc acattctgta aattagtgcc
    13741 attattttta tttattgtag tagctatcag cacgttttcg atccaacaat tcattgataa
    13801 cttttctagc gacattatat tgaatgcgaa tggacagccg atcccgtttt ccagtcaagt
    13861 attgagttgc atcatggtga tgctttgggt atttgttggt attgaaggag cctctgtcgt
    13921 aggttcacga gcaaaaaaac aatcagatgt tgggaaagca acgattctag ggatattcgg
    13981 cttgattatt atttacgtct tggtttccat gcttccatat gggacaatga cgatgaatca
    14041 gctgcaaacg atcaaggcgc agcctgctat gggctatgtg tttgaaatga tggttggtaa
    14101 atggggagca gtcgtgatca acggcggttt gatcatttct ttagttggtg tttggctctc
    14161 atggacgatc ttaccgattg aaacaatggg aaacatggct gaagacggac ttttgcctaa
    14221 agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat tgacgacgtt
    14281 atgtacgaat gtctttttac tttcattatt attcactgac agtgcttata actttgctta
    14341 cacacttggt acagcagcta ttttcttcac gtggcttttc ttaggattgt accaaatgaa
    14401 actttcttat cagcggaaag aatgggtcca atttttagta gggcttttag caagtgcctt
    14461 tcaagtatgg gctatgctag tcgtagcctt taatgaagta atgcttgttc ttgttctttt
    14521 cttgccaggc atttattttt acctcaaagc acgtaaggag caaaacgagc ctgtacaaca
    14581 tatccactta gataagattt tacttatagg tgtgacgatg gtcggagtga ttgcaatggt
    14641 tttatttgcc actgggatgc ttcacgtata gaagtataaa agaagtataa agagaggttg
    14701 tgagcctgtc gtttattcaa aaacatacta ggaaaggagc tgtgacacaa atgttgtcac
    14761 agctcctttt tcagaataaa cggtgtttaa gagacagcca atcggcaata aggctgaacg
    14821 tctctttcac agcctctttt ttgatgagtc atcatacatt ttttcgctta aatacgagat
    14881 atcctaatgc taagaacaaa acgatgtaag ctaaattacc gaatagcatt tgattagtag
    14941 aaagatgagt caattgcttc atgatctctt cgtttccaat ttggttttgc agattcaaca
    15001 tactgatcgg attccatttg atccactccc atttttggat gagtgcaata aggataccag
    15061 atatgattga cgaagcaaaa taaaagacga ttcctgctga gatggatgcg ccggaactat
    15121 tgataaagca agcaatcatc aacactaaac ttaaaatcag ccataaaccg atataactac
    15181 ccaaagtata agtgaacaag ctttggatca gtgtttgacc agtagaaacc ttctccgtga
    15241 aggaaatcga agggaaaaga atcagtttca tcaacacagt gacaataata gctaaaaggt
    15301 ataaataaac agaataaata actaatgtga tccatttgct tactaatatt tctcctcgag
    15361 aatactttcg ataaaggaga tttttcaatg taccatattg tgcttccatc gaaatgatcg
    15421 tgcttgcagc tgcaatcatg ataaagacaa tccaagatgt ggcactaaaa agctgagcag
    15481 tcatttcaac tggatcaatg atcgtcgtgt attttttggc tagaagtgct gttcctatga
    15541 gcaaaacaac taatagaaca gataaaacag cagttgactt tttcttgatc aatttaaata
    15601 attcttgttt tacaagcaat gtcatttttc ttcttccccc tttactgaat ccagaatttc
    15661 caatagagaa gattccaaat cattcgtcag atgctggacg tctgtcacat ggatattttg
    15721 tgcagacaat agctggatca cggttcctaa taattcttcg ttttctttta aaagcttgat
    15781 tttatcagga tcttccaaag tatatccagc ttctgtcaag atcgttcgag cagctagatc
    15841 atttgttgta gagataacga tgaaatcttg cgctgtttgg ttcaattcag ccattgtaca
    15901 ttgtttgatg atctttcctt gattgatcag gatcagctca tcgaccattt tttcaagctc
    15961 gctgagtaag tgactggaga tcaagaaaga ggtgccctga gtagccaagt cggtaatgat
    16021 ttttcgcaca tctcttgttg cttgtggatc caaaccgttc atcggctcat ctaaaataac
    16081 gatagacgga tggttcagta aggcaagagc aattcccaat ttttgtttca ttcccaacga
    16141 gtaggatttc gcttttttgt gaatgtactt ttccatcttg agctgattca cgatagtgtc
    16201 gatagcagat acatcgttgg tttcagagaa taacttcaga tgatcatagc ctgttaagaa
    16261 tggatagata cccgggtatt cgatcaatgc tcctacttgt tccaaccctt tatgactaga
    16321 gggagaaatc tcattttcac caatacagat tgttccatct gagtaatgga tcagtcctaa
    16381 aatagctttc atgatcgttg tttttccagc gccattagga cctactaatc caacgatttt
    16441 gccaggggat aagctaaaac tgacatcgct gagggcttgt ttgtgaccaa agttcttgga
    16501 taattcttgg accgaaagac ttttcaaaaa tattcactcc ttttctatag atagtacaag
    16561 catacacctg atgagtggag aagtcgctag gtcattggac ttatttctta ttttttcata
    16621 aaaaaattga atattaaata aaaaggctta ttttttctga tcagtactta ttccaagtgt
    16681 ctagtggccg ctagtaatct tgatgccaat gatactgatg agtagcatcc ccacaaagaa
    16741 ccaagtggaa agattcagct tatcatgaaa caagaccaca ccaattatga ccgaaccaac
    16801 tgcgccaatc cctgtccaga taggataaga gagactcatc ggcaaacttt tgattgcctt
    16861 tgacaaaaag taaaaactag caatcatgcc aatcactgtg taaaaagaat aattgatttt
    16921 agaaaaacca tcactccatt tcatcatcgt tgaccagaat acttccaaaa ttcctgctat
    16981 gattaattcc atccatgcca tacttacatt cctccttaac tataaaaaaa tacacaaaaa
    17041 gaggaaaatc atcccttcaa agacctaatg gaatgatcat cctctttatc ctacccggtg
    17101 gcagattgta tatctttttc tgtagtatag cacacctatc cagatatcgg caatctcata
    17161 ctttttagta aagtgtacca agcactgacg gatatatcgt tagcggaaaa gaagatgaat
    17221 gctttgcaat ttcatagaaa gaagttgtta tttattaatc atttaaaaaa aacagtaact
    17281 agaccttatt tctatatatt atcgggcaat aaattaaaaa aagctttacc ttacaataag
    17341 taagataatt tttgtgataa aaaaataacg aaaaatattt aaaaatagtg tctatttcgt
    17401 gagaaaacaa ctatattttt tatgtgtttt gctttataat taaaaaaata ttgtcatttt
    17461 atggaggaaa atatatggaa aattatctta gccttttagg cgtcttgatt gttattctcg
    17521 ggtttgcatt taaattagac tcgatattga tcgtaatggt tgctttagtt gttacagctt
    17581 tgactggcgg tcttggcatt caaggaatgt tagaactttt aggtacaagt tttgtaaaca
    17641 atcgcgggat ggcgattttt atcatcatta tgttggcaac aggaacgctt gaaagaaatg
    17701 gtctgaaaga atcagcggct tccttgatca agcgattcaa gaaagtatct gctggtatga
    17761 ttgtagatat ttatgggatc tttcgaatga tctttgcggc ttttaacgtg agttttggtg
    17821 gagttgctgg atttgttcgt ccaatcattt taccgatggc attggggacc atcgaatcaa
    17881 aagggttaga agtccatcct aagcatgaag aagaactaaa aggtatggct tcagctatgg
    17941 aaaatgtctg ctggttcttt ggccaagtac tattcatcgg aggagcaggg gcgttgctag
    18001 tccaatcaac actgaaagat ctaggatatg acgtaacatt gggacagctt gctttagtgg
    18061 aagttccagt ggctatcacg gctttagttg tggcaagtgt ctacttctat cttaaagaaa
    18121 agaaattagc gaagaaatat tatccaggaa aggggcaata agatggactt ttttacaaat
    18181 cctgatattt tattaggcga taaattactg gagatccttt atatcgtgat gggactcgta
    18241 ttgatttaca ctggagtaag aaatttaaca gataaaacca atcctcatcg ttatgggtca
    18301 gcctttttct ggacggtctt aggggtagtt attgcaggag gaagatggct tccggcaatc
    18361 gtgaacggtg gcttgatctt tgcgatgacc ataccagcaa ttgctaagaa agtcagcaaa
    18421 ggagaaagcc ggcttccatc aaaagaatat atggaaaaaa tgtcagacaa actaggaatg
    18481 aaaattttta ttccagcttt gagtatcggt gtctttgcga tcttgtttgc tctatttacc
    18541 aatttaggtg ctttagtcgg cgtgggcgtc ggtgtttttg cagccatgct aatcttgatg
    18601 ttcttttctc gagataatcg accaagtaca tttttagatg atgcagcaga tatgctgggc
    18661 acagtagggc cgttaagcat gttgccaatg cttttagctt ctctaggtgc ggtatttaca
    18721 agcgctggag ttgggacagt gatttccaat gcagtaggta cgatcgttcc agaaggaaat
    18781 gtgaacatcg gcatcatcat ttacgctctt ggcatggtga tatttacggt aatcatgggg
    18841 aatgcatttg cggccatcac cgtgatgacg gttgggatcg gtgcaccatt cgtatttagt
    18901 catggagcga atccagcgtt aataggaatg gttgcattga cttgcggttt ttgtgggacc
    18961 ctgctgacac cgatggctgc taacttcaat atcgtgcctg tagcgatgct ggagatgaaa
    19021 gacaaatacg gagtgatcaa aaaccagttg tttattgcgt tatttatgct agttttccaa
    19081 attgcttata tgattctatt taaataatag aagagagggg ttgtgacaga ataattgtcg
    19141 caacctcttc taacattgta gtggaacact atttttttat aagaatatat taagtttgat
    19201 ctgttatgtt atttaaacta ttgtttcctt tatttacgct gttcaaggaa aatggtatga
    19261 taaaagataa ccatatgtta aatcaatcgg acggaggaac aacagatgaa agtactagta
    19321 acaggttttg atccatttgg tggggacaaa gtgaatccag cctatgaagc agtaaaaaaa
    19381 atgccagatg aaatcagcgg tgctgaaatc atcaaagtgg aagtaccgac cgtattcgaa
    19441 aaaagcagtc aagtagtcaa agaagccatc caacagcacc aaccagatgt cgtgatctgt
    19501 gtcggacaag caggtgggcg gtcagcagtc tcgttcgaac gtgtcgcaat caatctagca
    19561 gaagcaagaa tccctgataa tgaaggaaat cagccattcg atacggcttt agaagaaaac
    19621 ggtccagccg cttactttac ctcattgcca atcaaagcaa tgacaaaaaa tgtacaagat
    19681 catggtctac cagcgtacat ctcttataca gcaggaacat ttgtctgcaa tgatatcatg
    19741 tatcgtttgc ttcatttgat cgaaacacaa ttcccggcaa ttcgaggtgg gttcatccac
    19801 gtgccattct cacccgatca agtgatcgat cgtccagtgg gtacgccttc tatgtcttta
    19861 gaagacattg cttcttcttt gacttatgca gttgaagcag cagtagaaaa taaagaagat
    19921 atttccggaa atgccggaac aactcactaa tttagcaaga aacactggct ggttgctaac
    19981 gttatgttag tagccagctt tttgtaatta gaaaggaaag aaacagccgt ggaagaatgg
    20041 caatccgtct ttgaagaatg gtttccaaaa gaaatcagca aaagctatcc catcaaaatt
    20101 tctaaacaat acacaagcag tcaacgttgg gagatctatg caaaattaac gaaaaaacag
    20161 cgggaactag tcgataagca ccgccgatat ctaatcagct ctcgttttat ggaagaacat
    20221 tatttagctg caacagattg ggtgttttct gacttcaaga tcaatccgtt ttttcgaaca
    20281 aaacgaagcc agcaaaaatt gtattgtgag tgtggtagag aattaaaagt gcaatacatc
    20341 gttaaatcgc caaaaaccgg aaagatccta aaactaggca tcaaccactt tgccgatcac
    20401 ctgcatgtct ctccgacagt ggcagcttcg atccatcagg gaatgacaaa agttgatctg
    20461 gccttagacg aattattatg gcttaagcag aagaatatcg attttcctga aggactatgg
    20521 caaaaatact gttttgtctt gtaccaaaat cgtcggatga aacagccata tttaccggat
    20581 ataaaattag ctcagcggct cgcagaattt cgccaagtag aaatgccgat ttacatagcg
    20641 gattatcaag cattggaaaa tgaaatcaag aaaataagtg aacacatcaa tgggcagtca
    20701 aaaaagcgac agataaaaaa agaactattt gacgactttg cagaagaatt agtaaaggat
    20761 gtagaagaat tcttgatcaa ctatcgcgca tttttacgta aagattggca atccatcgta
    20821 tatgaagaag tgccagtaca tcctaatgct tattttgaaa catttatttc cgtgttgaga
    20881 aagacaaaac gtcaacgaac accagaagtc actgctcaga tggaatattt tgcgaaaaac
    20941 caacgattca tccaaccaaa aatctatcta tttatttgga agcaatattg tcactatggt
    21001 tttacagaag ggttcttcga cagcattcct cggatagtca gaaatggttt tttaaaagta
    21061 ttgcgtaaag aacgagaagc tatacaatct gctgataaga aagaccgtac agtctcaaaa
    21121 gaaaaatggc aactagtagt gaaagatatc caatctggaa atgtgcaaga gacaatcgac
    21181 aaatggaaag gaaaacatta tcgttttact gaagctcaga aacaagcgtt ggaatattat
    21241 cagaagttag aagaatcact gcgtttcaat gatgaggcaa gaaagtatct gaaggaatta
    21301 ctataaaaaa tagaggctgg gacagaagcg tttaactcca agaaataaga agaaattcac
    21361 gaaaattgct tttcaaattt ttgtgaattt cagcttattt ccgaaggagt tgcttctgat
    21421 tccgccgttt atacgtgttt agagcgtgag acaaaagtgt tctttacttt tgtcccacgc
    21481 tcagtttttt tatgcgtgtt gttgtgcgtt gtagtattct tcttccattt tttgcatacg
    21541 ttcacgttct ttttggttat accaaggtga aacggtaaat gcaaggacat cattcagcaa
    21601 gtaaacagag ctgttcacga acatcgccaa acttgcagat ccatgcgtaa atgaaatata
    21661 ccaaaggacc atttgagcaa gccctgaagc taaccaccag taatattggt tgttgtaacg
    21721 caagaaactg atgataccag cagtcaagct aatagaaaaa gcaatggcat ctacccacgg
    21781 ccgaggatca tctgtataac gaccaatcag gaatcctgaa acaagataga caaggaaagt
    21841 actgatgatt gcgataaacc agctttttcc agtgaatttt cggatttttg aagccatatt
    21901 atgattccat tctttactta acaatacggg gatatccaat gtgatcatat aagcaatctg
    21961 ttcaccgata cttaaatagt tctttgctga aaacccaacg ataataaaac aaatcgcaga
    22021 caaaatacct aaaataccgt tgactgattt tgccgcattg atggataaaa tacacaatac
    22081 accaagcgtg gtaccgataa atgtaataac ggacagccaa gtgatgggac tattgacaag
    22141 agtcatgacc tggcagccaa gactgaaaaa gaaaagataa taattttgtt gcggccagcc
    22201 ttttagctga tgagctaaaa actgaaaata tgacttcatg tatgaggact ccttaagaca
    22261 ctaaatgtag tgtgttctgt atttactaac acaatctatt gtatgctttt cttgaaaaaa
    22321 aactagtctt tcaattataa ataatttgtg ttatgataat tttctgtttg ttttcttgaa
    22381 aatataattt cttactttca tttattatat tgggaacagg aagagtgtct tggaggacct
    22441 actttctgtt ttttttgcct tttttcttat aaaaaggaaa aacagctatt tttttcaatc
    22501 tgacacattt acaatggaac tggagattaa tatagatccg agcttaaacg aagaatagga
    22561 gtgctcatat gaaccttaca acgatccatc atatagccat cattgtttca gattatcaga
    22621 aatcacgtga tttttatgtt aataaattag gatttgaagt aatcagagaa aattaccgca
    22681 aagaacgaga tgactataaa ttagatctga aactaggaag tgctgaattg gagatttttg
    22741 gaattgctaa tgcgccacaa cgaccaaact atccagaagc ttgtggcttg cgtcatcttg
    22801 ctttcaaagt agacgatatt gaagaaacaa ttgcagaatt gcagtcctta gggatcgaat
    22861 cagaaccgat tagagaagat acctttacag gaaaaaaaat gacgtttttc tttgatccag
    22921 acggattgcc attagaactg cacgaataaa gataacaaaa ttgtcacttt tttttcgttt
    22981 cattcgattt ttcattcgtt catttcttga tattctttaa aaaaaagaaa caggagaatg
    23041 aagaatgaaa aaaatgatgt ttggtgttgc tgccctcatc gtaataggga ttaccggtat
    23101 gacgggactg ctcaatgccg cttttcacat ggatgatatt agtgaccagg aatatcggat
    23161 ctcattgaaa aaagcagcag caatcgtaaa aaacgaaaca aaagaacata acatatctgc
    23221 tattcatttt gcagttgaaa aagatttgga gaatcctacg aatgcaacat atgaatacca
    23281 gtttttttgt gaaggacaag tcatagcagt caatccatcc actgggaaaa caaccgtacg
    23341 aaatgacacg gaaaaggccg cagaacatct ttttgatata gaaaaaacgg aagagttcaa
    23401 acaaccgcaa gcagcgatga aggaagcagt cagctactac gggaaaaaag caaaagtgaa
    23461 agagtggaca cttctagtca aagatgaacg tccttattat aaagtccgat taatagatgg
    23521 agaacaggac cgtcaggtat ggatatctgc atagaagaag gatattgctt ctctttttta
    23581 caatataaga gtaagctaag agagtaaaga tgaaaggaag ttgagataac atggaaaaaa
    23641 tgaaatgccc taattgcgga aaaaaatttg catacgaaga agtcaataat gtagtcgaac
    23701 ataatgataa agaaatgcca gtcgtctgcc cttattgccg aactgaagcg gcaagaatcg
    23761 ttactcatgg ttatttcatt actgaaaaga ttgaagattt tttaaaataa cgattttgcg
    23821 atttcttttt ctgcatgtta gaatggagaa aaggagagga aactatgatt cgttttgcga
    23881 gaaaagaaga tgctccagaa atcgccccat tgatcttagt gattctaaaa gatatggaac
    23941 tgccattttt gaagcagaca ggggaacaaa agactttaga gattttagaa gaagcaatca
    24001 ctgatccaaa ttatcgttac agttattcac gaggtatcgt agaagaaata gacggtaaag
    24061 ttgcaggagt tgcttacggt tatacagatg aagaagaatc aatcatcgat cagccactgg
    24121 tacctatctt agagaaatat cagctagatg cgtctacacg tttgttcatt gataaagaaa
    24181 cgtttcccaa cgaatggtat ttggactcta tcagtgtatc agaagatttt agaggacaag
    24241 gcatcggttc gcgattatta gaagcattac ctaaattggc gaagaaagct aatcgctccg
    24301 tcatcggtct aagtgtggat gaaaaaaatc caaaggctaa aaaattatac gaacgccatg
    24361 acttcaaagt tgtcggtcag cggatgatca gtggtcatct ttatgatcat atgcaaaaga
    24421 atatctaaaa agatgtacct gaaatgcgta tttccgcatt tcaggtacat ctttttaact
    24481 taagttaagt cggtaagaaa caggcttatc gcgacttttg tctttacggt agagccagta
    24541 atctaaaacc gcagcaatac aaatacaaac tggagcatct tcatcatttg agacatccaa
    24601 tacatagtaa tctcctgaaa aaagtgttgc tttatccatt ttcatgattt gctgattgaa
    24661 atgatggatt tgatattgat gattatagat atcaccttgg actgtccagt gaagtctacg
    24721 aatataataa aagtcaccgg gccaattgaa tattttctgc atggttccca ccttttcgaa
    24781 ctctttatac agctcaaaac gcgtaccgaa tgtcaggctt atctgcttga tgtgagcaac
    24841 gagatcgcca ttcatggcat aaagagacaa tgcatcgccc tttgttcccc agcgaccaac
    24901 catcaaaaac agggaatgtc ctttttcgtt tttgacaatt gtccgagttg cacgtccaag
    24961 ctgcttttcc tgaatgaaaa attctgacat ctatatccct cttttctaga taaaactaca
    25021 agtcttctgc aatcgcgcgc aatatggctt ttcctacgcc agattcaagg tttgtgtccg
    25081 ttgtatattt ggcataatct tttacttcga tttctgcatt tcccattgcg aaactgactc
    25141 ctgctacttg cagcatgctg acatcattga agttatcgcc aatcgtcatg acttcttcta
    25201 aagaaatccc acgctcgtga gcgacatggg caacagcaat tcctttttga gcgtttttat
    25261 ggttcacttc gatattgttt tgaccagagg aagtaacggc tagatcgcct aaaagagaaa
    25321 tctgctttcc aactggacct aatacagctg gcccttctgt atgaaaacaa ataattttta
    25381 aaacttccag attcttttct tccaaaatag cacgaatact gtccacgtat gtgatgtgca
    25441 ataactccag cttagctgag gccatggcaa tcgccatttt atacgtaagg tgaggtaaat
    25501 gggtagccac catggaagca aaactttcaa ttcgtttcgc ttgattttca gaataaagac
    25561 catcgttggt tgctacttca tagtaaatac cgttagcatc tagaatatct aaaacagaga
    25621 ttgcttgatt atttggaatc gacacggtaa acaatgaatt tccttcttta tcaaatacct
    25681 gtgccccgtt caaagtgatc atcgcacaat cgattcctac ctcatctaaa gctgcgcgag
    25741 cttcttgata gtttcgacca gtagcgacca tgaactcaac accggcatca tttgcaaaac
    25801 gtatcgcctc ggcattttca ggagaaacac tcatatgggc atctaataat gtgccgtcca
    25861 tatctgatgc aattaatttg atcataatga ttatcgttcc tttctgcttc ttgttcctag
    25921 tttaccatat taatcaagtg ctgagggtga agattgtccc ttgtgattga agaaaatgtg
    25981 agttattctt tttattagga ggtggagttt ttgaaagaaa tcattcataa cagttggcaa
    26041 gaagttttgt cctcagaatt ttcaaaagat tattatctgc atctaagaga atttttaaaa
    26101 aaagaatatg cgtcccaaaa gatccatcca gatatgtatc atatctatga agcattggaa
    26161 ttgactcctt atgaagaagt taaagtggtg attttaggac aagatcctta tcatggagaa
    26221 aatcaagctc atggcttatc tttttctgtg caacctggcg taaagatccc gccatcgtta
    26281 agaaatatct ataaagagct ttatgatgat cttggaatcg cacctgttca acatggaaat
    26341 ctagtgtcat gggctaaaca gggagtcctt ttactcaaca ccgttcttac cgttcgggaa
    26401 gggcaagcgt attctcatcg cgggaaaggt tgggaaagat taacagacac gatcattgaa
    26461 aaattaaatg aacgggaaaa accaatcgtg tttatcttgt ggggaaaacc ggcacaagaa
    26521 aaaatcaaaa tgatcgataa gagtcgccat atcatcataa catctccaca tcccagtccg
    26581 ttatctgcaa gtcgtggctt ttttggttcc aaacccttct cgaaaacgaa tgatgcgctc
    26641 cttgcgttag gagaagaacc gattgattgg caactgcctg aaacagtgta ataaaacagc
    26701 gctttcctgt tatagtgcag ttcgctttgt atgtgaaaaa cttaattttt ccagcatttt
    26761 tgactgatac agataaaata aactgttctt tttttctgga atagtgtatg ataatacata
    26821 taaaaacgtc tggaggtcat cttgtggaat tgtttgatag tttaagattt aaaattgttc
    26881 gccgtgggat caaaatcgtt ttcccggaag ctactgatgc tcgtatttta ggcgcagctg
    26941 cccggttgaa agcagaagaa cttgtggaac ccattttagt agggaacgaa gaagaaataa
    27001 gaaatgcagc gcatgccaga ggaatcaaaa catctagctt tacgatcatc agccctgata
    27061 attacgataa gtgggatgaa atggtggata cttttgttga acgtagaaat ggaaaggcat
    27121 ccaaagaaca agcagaaaag attttaaaag atgtgaatta ctttggtacg atgcttacgt
    27181 atatggggat tgcagacgga atggtctctg gagcgatcca ttcgactggc gacactgttc
    27241 gcccagcact tcagatcatc aaaacaaagc ctggcatcag tcggacaagc ggagcgatga
    27301 tcatggtacg tggaagagat caagaaaaat atgtcttttc ggattgtgcg atcaacgtga
    27361 atccaactgc gcaagaattg gctgaaatcg ccgtagattc tgcaaaaaca gcagaattgt
    27421 tcgatatcga accaaaagta gcaatgatga gcttctcgac aaaaggctca gcgaaatcgc
    27481 cagaagtaga caaagtagtt gaagcaacta aaatcgctaa aaaactagcg ccacaataca
    27541 tgatcgacgg cgaattgcaa tttgatgctt cttatgttcc ttcagttgca caactgaaag
    27601 cgccagattc agaagtagct ggtcaagcaa cagtctttgt atttccagaa ttgcagtcag
    27661 gaaatatcgg ctataaaatt gctcagcgtt tcggtaactt tgaagcaatc ggaccaattc
    27721 tacaaggctt gaacaaaccg gtttctgatt tgtctcgtgg agcaaatgaa gaagatgtat
    27781 ataaattatc gattatcaca gcagcacaaa cattgattga ttaacaaata cacgcgaact
    27841 agccaaaaac agcagctgct gttcttgact agttcatttt ttctttaaaa aaacttcatt
    27901 acgcgatata ctggcaaaaa gaaagaagag cgggagaaga tgaaaaatga tcgaactatc
    27961 aggattaaca atgacagaac aattcgcaga ggcaattggt cattccgcaa tgccaggtga
    28021 caatctgata ttgactggtg atctaggtgc gggtaaaaca acgttgacga aaggaattgc
    28081 ccaaggatta gggataacgc aaatgatcaa aagtccgaca tacacgatta ttagagaata
    28141 tagtcaaggt cggattccgt tgtatcatat ggatatttat cgggtagcag ctagcggagc
    28201 agatttaggg ttagatgaat attttgaagg tgatgggctt tccgttgttg aatggggaaa
    28261 tctattagaa gaagcactgc cggaggatta tttggaactg attttagaaa aaagtgatac
    28321 agatttagaa aagcggtatg tgaaactaat ctcatacggg gagcaaagtg aaaccttcaa
    28381 acagcgaatt ctagaaaaat gggctgaaaa tcatgagtga agaagttggg atcatcttgc
    28441 gggaagcagt gccaggagat gcaaaagaca ttcttttgat gatgggacaa gttaataagg
    28501 agacagaatt tttagttttg gatgaagcag aactcctgtt accaccagaa accttagaag
    28561 aagagttgga ttatatatac gaaagcaata ataatttatt gctgcttgca atctatgaag
    28621 ggacgattat tggaacagca tctgtcaagg cagacagtca atttcgtttg tctcacgtgg
    28681 gagaagtcgg tatcagtatt ctgcaggaat attggggaat gggactaggc actcttatgc
    28741 tagaagaaat catcagttgg gcgaaggaaa tgggtgtact ttttcgattg gagcttgacg
    28801 ttcaagttcg taatgaaaga gccgtacacc tttaccgaaa aatgggcttc caaatcgaag
    28861 cggtcatgcc tagaggggca agaacagatc taggtgaatt tttagatgta tataaaatga
    28921 gttatttgat tgaatagaag aaataggaaa agagtgagaa actgtcatcc ttttgagaag
    28981 gcagaaaaac acacgaaggg actgtgacaa aagtcgtgtc gcagtccatt ttttttgaat
    29041 aaacggtgtt caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa
    29101 ctattttgcc gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttgg
    29161 taaacggtgt ccaaaagctt gcatctgcgg taataagtcc aaccaaatga aaaatatgag
    29221 aagctatttt tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct
    29281 ccaataaacg gtgttctcct gccagctcct cggtcaccag tcacaatatt taataaacat
    29341 gagaagctat tttttgaaat tgctccttgt gactcggagt gaaacggcag gctcacgacc
    29401 tctttgtgtg tttcataagt attcttttac tttatagtca caagtttttt caatggatct
    29461 gtcccgaatt ttttttcttg ataaagcagg atttccgcac atgcacgact atcttccaat
    29521 gcatcatggt gatgatctaa ttggatgttc aaattttcgc acacagtgtt caatcgatga
    29581 tttggaaatt caggaaacag gcgacggcta cttttcactg tacataaaga aagataatta
    29641 ggctgttcaa gatgataata atctaagcat cccgctaaga cctttgtatc aaaagcagca
    29701 ttatgtgcaa cgactaaacg atttttttga aaatatggtt ggatagtttg ccagacttct
    29761 gggaatttcg gcgcattgcg tacgtcttct tgatggattc cgtgaatttg gacatttcgc
    29821 cagaaaaaag gagtctcagg ctgtatcaat gtatagaatt catcaacgat ctggctattt
    29881 tttaccatga ctagcgcaag agaacaagca ctataaggct gatgattggc agtttcaaaa
    29941 tccatggcaa caaaattcat ttctgtaaaa cctccttggg aaattactgt aacatacttt
    30001 tgaaaaaagc aaataaattt aacaaaaaac atagaatttt ttatgtaata tttgttgaga
    30061 aaagctagtt tttgaactca ttccttgtga tttggagtta gatggggatc atgacttctc
    30121 ggtattaagt caaatttatg caaagttgtg aggaaccatt ttcaaaaaaa tttcttacga
    30181 ctcgaaagta ggcgactttt tcacaacttc tccactaaac ggtgttcaat cagctgaccc
    30241 tcggtattag ctcaaaaaat agcaaaatat gaggaactat tttgccattt gtttctctaa
    30301 tactcaggtc aggacgctga tttcacaact tctcaataaa cggtgttcaa aagcttgcat
    30361 ctgcggtaat aagtccaacc aaacgaaaaa tatgaggaac tatttttgtt tggctgttct
    30421 tattacttga tgcagtgcag ctttttcaca acctcttaat aaacggtgtt caaaagcttg
    30481 catctgcggt aataagccca accaaacgaa aaatatgagg aactattttt gtttggctgt
    30541 tcttattact tgatgcagtg cagctttttc acaacctctt aataaacggt gttcaaaagc
    30601 ttgtatctgc ggtaataagc ccaaccaaac gaaaaatatg aggaactatt tttgtttggc
    30661 tgttcttatt acttgatgca ggacagcttt ttcacaatct ctcgataaac agtgttcaaa
    30721 agccagtttc tcggtattat gccaaattta tgcaaaatgt ggaaagccat tttcacaaaa
    30781 tttttcttaa tactcgaaac taaacgactt tttcacaacc tctttatttc aaatctaatt
    30841 ctactggaca atgatcactg cccataatgt ccgtatggat ctttgcatca gctagtcctg
    30901 gctctaaatc tttgctcgtc aaaaagtaat cgatccgcca accagcattg tttttccttg
    30961 aattgaatcg gtagttccac caagagtaga caccttcctg ggttggataa aaataacgga
    31021 atgtatcgat aaacccgtta tccaacagtc gagaaagagc cgctctttct tctggagtga
    31081 atccagcatt tttttgattc gttttccagt ttttcaaatc aatcttttga tgagcgacat
    31141 ttagatcccc acacacgatg actggttttt gtttttttag attttccaaa taattataaa
    31201 aggcttcttc ccattctaat cggtaatcta aacgttttaa ttcgctttga gaatttggcg
    31261 tgtaacaggt tacaagaaag aaatcggaat attccaaagt aatcagacgg ccttctgtat
    31321 catggatatc gatacccatt ccgtaagtgg cattcaatgc tggtttttta gcaaaaatcg
    31381 ctgtgccgga atagcctttt cgttccgcgt aattccaata ttgataataa cctggaagat
    31441 ctaaatcaat ttgtcctgct tggagtttcg tttcctgcag acagaaaaaa tcggcgtcta
    31501 actcatgaaa aacttctaaa aaatttttat ttacgatggc acgaagcccg tttacgttcc
    31561 aagagataaa tttcaataaa agcacactcc ttcgaattaa tttccttacc tttgcgatac
    31621 tattgtacct cattttagta aaaaatggtg taagatgaaa gtaactaaat gatccaggag
    31681 gaaagtagat gaagattggt gtaatcggtg tagggaatat cgcagaaaaa gcatatttac
    31741 caacttatgc gaaaaaacaa ggaacacttg atttttattt tgcaacaaga aataaagaaa
    31801 caaaagaaag aattcaaaaa gagtacgggt tccaacatct atatgaaacg atcgatgagc
    31861 ttttagaaga aaaaatcgaa gcatgtatga tccacgcagc aacaaaagta cattatgaat
    31921 tagccaaaaa atgtctagaa aatggtatcc atgtttatat tgacaaacca ctgagtgtcc
    31981 atctaaatga agttcgtgaa ttgcaagaat tagctgataa gaaccaaata attttgatga
    32041 tcggtttcaa ccggcgcttt gctcctatgg tagaagaatt gaaacgtatc ccagataagc
    32101 ggttgatcca cctgcaaaaa aatcgaatag cggcaaaaga aacgacagag ttcgtccttt
    32161 atgatttgtt tttacatctt attgatacag ctgtgtattt attagatgaa cccattttga
    32221 gaacaaaata ccagataaga gaaacaaagg aatttttgga atatgccatt ttacaattag
    32281 aaacacaaaa tcaaacggct attttaacga tggatttagc aagtggcgct aatatagaaa
    32341 aatatcaagt aacaagtaaa aatggtactt atgaagtaaa cgatctgacc cagcttgtca
    32401 ttcaagatgc tgatggaaaa aaagtgaaag aatttggcga ctggacaaac acgctagtca
    32461 aacgcgggtt tgagccaatg gtagaggcct tcttttctca gatccgttta ggtaaatcgg
    32521 aaacagaatt gcttaaacaa aaagaagttg taagaagtca tgaattatgt gaggaagtgc
    32581 ttaaagatca ctaccgtcat caactttgaa caagactggc aagattgtat taagcgtgat
    32641 agaataatga ggacgtttga gaaaagaaag gaaaatcctc agtgaataaa gaagaaatag
    32701 ttgaaagctt agccacgatt actatattgt ttgatgaacc attgatgaac tatacgttta
    32761 cgaaaacagg tggaccagct gatgtccttg cattcccgaa aaaacaagaa gaagtaaagc
    32821 aaatcatcga ttattgccga atccatgata taccttggat ggtattagga aatgcaagca
    32881 atctgatcgt tcaagatggc gggattcgcg gtgtagtcat catgctgact gaaatgaaac
    32941 agattcatgt caaaggaacg atggtcattg cggaagcagg tgcctcactg attgatacga
    33001 cttatgcagc tttggcagaa tcattgactg gatttgaatt tgcttgcggc atcccgggaa
    33061 gtgtcggtgg agcggtttat atgaatgcag gtgcgtatgg cggagagatc aaagatgttt
    33121 ttgctgaagt ggatcttttg cttgaagatg gaacattgaa aactttgaca aaagacgaaa
    33181 tggtattttc ttatcgtcac agtaaagtcc aagaattacg tgctatcgta ttggaagctc
    33241 gattcagttt gcaaacaggg gattatgaag caatcaaagc aagaatggat gagttgaccg
    33301 aattgcgtca atcaaaacag ccattagaat acccttcatg cggaagtgtc tttaagcgcc
    33361 cagtaggaca ctatacaggt cagctgatcc aacaagcagg attgcaaggc ctgaaatggg
    33421 gcggtgcaca agtctctgaa aaacatgctg gattcatcgt caatatcgat catgcgacag
    33481 cgacagatta tattgaattg attgcgcaca tccaagaagt aatcaaagaa aaatttgatg
    33541 tgtctttaga aacagaagtg cggatcattg gagaaaaaca agcaatatca gaaacaagca
    33601 gaagtttagc caattaataa gtaatggaac ttaaaataag taaaagagca ggacggtggc
    33661 cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca aatcttgtac attttaacac
    33721 aataaaacaa aaaatataga atatttcctc ataaattttt ccattttttg caatattctc
    33781 aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca agcataatcc atcataaaat
    33841 cagtataggt gaaaagatga actttcatct gcatatcaag taattggtat gaggcatttt
    33901 ttgaggtgta ggatatgaag ttggattacc ttatagaaga ggaagataga gaaaaactgc
    33961 tgctagctag atatttagaa tttgagaaaa agaattatgt agtgctgcct aagttatatg
    34021 aaacattagg tttgtctaaa tttaaaacaa gaaattatat catagaatta aataaagaat
    34081 ttactgaatt caaaacaaag ccagagatcc aaatttcaga agaagcagag atccatgtcg
    34141 aacgtctgaa tttgacggat atcaaaaatt taagaagaat ctactttcaa cgatcaaaaa
    34201 ttgctcgact gttaacggag atcgtggatt caaaagtaac gatcgaaaaa tttgcagaga
    34261 atcatttttt aagcatatca agagcctatg taaaaagaag agaattagtc tcttttcttg
    34321 aacagcatca aataaagtta aagaaaaaca tattagttgg ggaagaaata aacatacgga
    34381 acgtattatt tggggtatat ttcggggtct ttaatggttt ttctatgcca tttagagaaa
    34441 gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga atatctgttc aatttaaaac
    34501 tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac tattagtttg ttgagggcct
    34561 atgggaatca accaatcgga aaacgtttct tttcagatga atactttaag agctcagaag
    34621 gaatgaagat catcaaggat ttatcacata tttcttttct tcatatccct aaagagcaga
    34681 tcattgatga gatttcttat atcatgttgt ttttgatcac ggaagaagaa tttgaattag
    34741 atggcgcatt tggacttgcg gaagctcatt ttcatgatat ccacatgatt agtcaaaaaa
    34801 tgtcagtgga attgattgat caattaccat tttcgattga aatctctgaa gaagaaagac
    34861 tatatatacg aaaagaactt cgtatgggta tgatgcatgt caatcgaaaa aattggatat
    34921 tcgactttga gatgactagc tttacgtcta aaaagcagct acagtttttc ttcgagacgt
    34981 atccaatatt cagtacagca atccaaaagg tcatacaaga gaataaacgc tatttcttgg
    35041 gaaaagatga acgtttcatg attcgcttat tttatgatta tctcttttta ttggtcggta
    35101 tttgtccggt atcatatttt gaagcaccga ttcatgtctg tattgatttt tcgcaaggat
    35161 ctgcttatac cgattacatt atttctcaag tgaaaggatt taaaaattac aatattgtga
    35221 ttgagagtcg aatcacttct cgtacgaata tttatttatc tgattgttta cttgaaaaat
    35281 ttaataaaga acagataatt tggaaaaatc caccgactcc agatgactgg gaatattttg
    35341 gaaataccat catcagagaa aaaaatagac atttaactga aaaaatcagc tagtatttat
    35401 ggatggcagc tttgtctcac atatttatta gctgatttat gtttttttca aagaaaaggt
    35461 aactagatat aactagatat aactagatat attacttaac aaaattaaaa agtacataag
    35521 ttattattcc gattttcttg aaacaataaa aaatcaaaaa aaatactctc ctaatagtcc
    35581 atcttctttt gattttattt atataatgaa atcatcttat gaaaattact acttcatgtt
    35641 tagacaagag tagggaggac taagaataaa tgtgttcaaa aagacgttca aaacaactaa
    35701 ataaacacgc ttgtcgttta gataaggaac ggtcgtgttc tgaaaaacac tacgttaagt
    35761 ttatgatgcg cacgatgctg atcagtttat ctgtaggtgt ctatatgcat gtacccgttc
    35821 aggcaacgac acaaaccatc aaggtcgtac gtacctctgt ttctgagacc actgattccc
    35881 ctatcactat tactcatact ttcactgatg caaatggaaa acagctactt cctgcattga
    35941 cttcctataa taaagtcagt tatcctccaa cgataaacca ctactggtta attcctaaca
    36001 aaacattatg gacatcggaa accggaagca gtgtgccgct ttctatcttt tccgatatga
    36061 ctgatcctac aaaaggtgat cagttaaaac agatcactga tattttgaat catgctttga
    36121 cagatataaa ggacggtgga agcgcacaag tttcttatgt atatgaaaaa gattattcac
    36181 agtttgaaag aaagaaaatc gatgttctgg cagggacaaa agtttcgata tctgatctgg
    36241 tagaaaggct gaagaacgca gatggaacac aaggagatat gtccaaagta atttcaaaca
    36301 atgggaatat cgtggatacg actaatacag gaacatctac tatttccttg tcctattttg
    36361 atccaattgc tttaaaaaca atgactgcat ctgctgtgat ccatgttcgt gctgatcaaa
    36421 cagctatcaa aggaaaagat cttcacttaa gaacaggaga gagttacgcc cctaaagatc
    36481 ttgttgaata tgtaacaaaa agcgatggaa cttcaggaaa taaagaagaa atcaaaatga
    36541 acgggacagt agatactaca actccgggag aatatcccgt tgtattaact tatatagact
    36601 cgaaaacatc aaatgtggca gaaacaacag ctgtagttta tgtagaagca tctgctgctt
    36661 catcgactgt catcactcat tttatagata gtcaaacaaa taaagaactt caagcagaaa
    36721 cacatatgag tagtgtaaat cgtattcctg atttgcgcct acctgctgaa ttttctgatc
    36781 gagtgccaaa tatagattta tcgacttatg aacaaaatgg gaaagtcact tctatttctg
    36841 attggatgca agcaaacgga ttagacagaa aaagtcactg gtcggagatc cttgaagtac
    36901 ttcactcaga actgatgaat aataggaagc aatcaggagg ggaaattacc tttacttatg
    36961 tttatatacc agacaatcgt tcattagaag gtcatgatct tattgttcat ccaaacgaaa
    37021 aaataaacaa agaagagttg atccaatcag caacaaattc cttaggtaaa cccgtaccgt
    37081 taaaggatgt atcggttaca atcaatgaag taccattgga ggatggttat ttgaccaaac
    37141 aaacaggtga ttttacgatt atgtatagtt atcatgaccc gtattcactc caagaactcc
    37201 atgctcagtc actattacat gttttaccat taaacaaaca gatagatcaa aaagaacaaa
    37261 aaagacaaga agaaagcttg tcagaaaaaa aacaacaaat ggctcatgca gtttctccaa
    37321 cagggaaagt aaaacaaaca agaagcctag agttagcaag aatatctaga aaaatctcag
    37381 aatctaataa aacgataagg caagaagctc atttggcccc acaagtttct ggattggaaa
    37441 atgaaatttt agagcctaaa ataaaacaac aatcagaaaa agaatttgtt gctaaacagt
    37501 cggaagatca gaaggaatca gatgaccaga aggaaacgaa gaaaaaacgc ttgtcaacta
    37561 ttgattccac cgatgagcat ctgcagccgc aagtaccact tcctagtccg ggaacacccg
    37621 cacctggtgg aggtattcct tcttctgctt taggagattt catgcgaggt atggcaggaa
    37681 catgggtata cgctaatcga aatgaatttg acgcagatga ctggttctga tttatatctc
    37741 tatctgttat agtcaaataa gtagctgagt catatgttat ttggcataat ggagacgagg
    37801 agggatagaa aaatgttaga taaaacgtta ccttacgcag aaatctggat gacaagacca
    37861 cttcaacaaa atgttccaat cacgccttta gcggaaggtt ttgaatttcg attttatcaa
    37921 aaagaagatg aatctgcttg ggcggagatt gagacttccg ttggggaatt tcaaacgaca
    37981 gatgaagcac ttgagtattt tcaacaaaac tttgctcctt atcctgaaga acttgaaaga
    38041 aggatgtttt ttgtagagac aaaaaaagga gaaaaagtag caacctgtac cgcttggcga
    38101 aaaaaatcaa gagagcaagt gtatccggtt tttcattggt tagcagtgaa accagattac
    38161 caaggaaaag ggctcgcaaa agcattgact gccagagtct tgcaagaatt tcctaccctc
    38221 catacggacg gaccaatcta tcttcacaca cagacatgga gccatcaggc gattgctctt
    38281 tataaaaaaa tgggttttac ttttattgct gaaaatctag acggcacacc taatccagat
    38341 tatgaaaaag ttatgcaggt tttaagtaaa ttagataaat aacgaaatgg tgaaataagt
    38401 cctcagtatt gggataaaaa acgaaatagt cattcctcat atcttacttt tttgagttaa
    38461 tactatcgga taactaatgg catgccatac attcaaaaaa gaaggggcag tgacaaaagt
    38521 attgtcactg ccccttctct tgttttttag catgttttat cgtttgattt ttttaggaat
    38581 aaaattcttg atgaacgtaa atttttggta atcgtttcga ctatagaggt aaccaaatac
    38641 actgaaaaca actgctccaa taaaattaac aaataaatcc ttcatagtat ccatgattcc
    38701 cacgtctaag taaccatttt ggatgattgt tttatctgtt ttaccatctg cattttgact
    38761 ttcaatgatt gtccgagtga tatctggaac atgatagaca gtgtttccgt ctttacttaa
    38821 ctccacacta ttgatttgct ggatgatcgt atctttttgc atatcgaatt gcagtaattt
    38881 atctgctgaa aattccacaa actcccacat aacaccaact gtcatcgaaa aacagaagga
    38941 aacaactgct agtaataaag gagtcaagtt catggttttt gtatttttat tgagcaaata
    39001 aacaagggaa aagccgacac ccccagctaa aaatccgctg aatgcatgta gaaaagtatc
    39061 ccacattgaa aaatagccat aaaaatcact taactctcct aaaactgttg aactaaaaat
    39121 aaaagataac aaaatgattt ctagcatatt tggaatctgt atctttaata tcttttccag
    39181 aaaataaggg atttcaaata aaattaatgt cagtaataaa agcattgtat ttccccagtg
    39241 ttggttccag acctgatcca ctagcataat aacgacgatg atacgtaata aaatatagat
    39301 tccgtttgtg attctacctg cagtttttgt actgttcgta aaaaaggttt tcaaatgatt
    39361 cataaaataa ctccttcatg tatatcctta attatactaa gaagcgtgtg tttaccaaag
    39421 ctatatgact taaagaaaaa cagagttgat attgtgaaaa aaatcactta atatagtata
    39481 aggagaaaag ggggatacaa atgaaaaaat tagttgctgg tttattaaca gccgttgcac
    39541 ttcttgctat gagcgcatgc ggcgcagatc agaaaaatac agcgcagaca agttctagta
    39601 cgaaggaatc tgccgaagta tcatcaggcg cttctgaaca agtatataca gatccaaaag
    39661 aaatgaaaga atcttatgat gtcgtgatta ttggagctgg tggtgcaggg atggcagcag
    39721 ctatcgaagc aaaagatgct gggttgaatc cagtaatttt ggaaaagatg cctgttgccg
    39781 gaggaaacac atctaaatca tcaagcggta tgaatgcttc agaaacaaaa tttcaaaaag
    39841 aagaaggaat caaagactcg aatgatgcct tctatgaaga aacgctaaaa ggtggtggag
    39901 gaacgaatga taaagaaatg cttcgatact ttgtcgatca ctctgctgat gcggtcgatt
    39961 ggctagatca aaacggtatc aaactggaca acttaacgat cactggaggg atgagtgaaa
    40021 agaggacaca tcgtccgtct gatggctcgg ctattggtgg atacttagtg gaggggttat
    40081 tgaataacgt ccatgagcgg gaaatcccta tttttgtcaa cgcagatgtg acagacatta
    40141 agaaaaatgg ggaaacggtc aatgaagtga ctgtacatgt tcaaggagaa gaaccaaaag
    40201 aggtcaccgg aaaagcaatc gtagttacca caggcggttt tggtgccagc aaagaattta
    40261 ttgaaaaata tcgtcccgat ttagctgatt atattacgac aaatcaagaa ggatcaactg
    40321 gagatggtat caccatgatt gaaaaattag gtggacaaac cgttgatatg gataaaatac
    40381 aaattcatcc aactgtgcag caggatgagg gggtcttgat tggtgaggtt gttcgcggag
    40441 aaggagcaat cttggtcgat caagagggga aaagatttgt caatgaaatg gatacaaggg
    40501 ataaagtatc tgcagcaatt acagcattgc ctgaaaaatc agcttatttg atttttgacc
    40561 aaggcgtgcg tgatcgtgcc acagctattg aattttatga ccaaaaagga tatgtcacaa
    40621 ctggaaagac aatggaagaa ttagcagaaa aaatcgattt accaaaagaa acactagcaa
    40681 aaacagttga tggatggaat acggatgttg cggagaaaaa agatgctcaa ttcaaccgtg
    40741 ccacagccat ggaacatgac ttatcgtctc cgaattatta tgcgatcaaa atcgcaccag
    40801 gaatccatta cacgatgggc ggtgtgaaaa tcaatacgaa cactgaagta ttagataaag
    40861 aaaaccagcc aattaggggg ttatatgctg ctggtgaagt cacaggtggc ttacatggaa
    40921 acaaccggat cggtggaaat tcagttgcgg agatcattat ttttgggcga caagcgggca
    40981 tacaagcagc tcgatttgct tcggaaaatg aatgaaatag aacgtaaata aaaagaggtt
    41041 gtgaaatcag cgttttgagc taataccgag ggtcagctga ttgaacactg tttagtgaag
    41101 aggttgtgaa aaagctgccc tgcatcaagt aataagaaca gccaagtaaa aacagcttct
    41161 tatgttttta acttggttgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    41221 cggaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    41281 aaacggcgga agcagaagaa attccttcgg aaataagctg atattcacaa aaatttgaaa
    41341 agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    41401 ttttgatcag catgatttta ttcagttatc ttcaaaatga tttttccgat gtttttgttt
    41461 gcttccatat attcatgcgc ttgtttgact gcgctgaatt ggaatgtacg gtcaatgatt
    41521 ggccgaatct tgccattttc tagaaaaggc ccagcttttt gcataaaagt ttgtgcgagc
    41581 tctgctttat actgatcact tctaggtgtc aataatgtac caagcagttg gacacgtttc
    41641 ccaatcaata caccaaggtc tatctcaggc acgatggtcc cacctagcat accaatcaag
    41701 acccaacgtc catcaacggc tatagaagct aaattctttt cccagtaaga agcgccgatg
    41761 aaatccaaaa taacatcgac tccccgacct tcagtgattt ttcgtacctc ttcttgaaag
    41821 tcttgttttt tatagttgat caattcatct gcaccaagtt ctttacaaaa ggcgagtttt
    41881 tcttctgatc ctgcagtaac gatgattttc gcgtgagaaa gctgtctagc taattggatc
    41941 gctgctgttc ccacaccact tgctcctgca tggatcaaga cagtttcgcc ttcttgtaat
    42001 tttccaagct agtaaagtgt ttgataagca gtcaaaaaaa cttctgagat tccagcagca
    42061 gaaacatagt ctagcgtatc agggagaagg attgcacgat cggcaggcat cacagcatat
    42121 tcggcataac cacctagatt gactaatccg tatacttttg tcccaggagt aaaagtggag
    42181 atatcacttt tattctcaac tacctctcca gctacttcga ctcccaaaat agggtaggga
    42241 ggtttcaaag agactgattc tcttttcata atatctgttc gattgacagc tgctgtatgg
    42301 actttgatca gtaattcgcc ttgttttggt ttaggaacag gcacttcaat ttgttctaat
    42361 acatctacag aaccaggatg cttgattgaa atggcacgca tggatctatt cctcctttgc
    42421 ccattcttgg aatgctgtat tcaactcttt gctaccttca gaaagtacta gagtcgtacg
    42481 agaaatatcc gtttcttcca ctagagcggc aagtacagca gcaactgtag agcgagtgat
    42541 cgtttttgat gccttctcat taggcttagt taattgaatg gaagtaactt cttcatcgtt
    42601 agtcaatgtg actggttgaa gaatgacaaa atctaagtta gttcgtttca gccattcatc
    42661 tgcataatgt ttagtaatat aataatctgt catggactca ggccattttg ctggttcatc
    42721 tgcataaaca gcactgacca tcagatagcg agagacatgc gcattttcag ctgcgatcac
    42781 tgttttgatt gcgccatcca agtctacttg cagaagattc tttccttgag agccggcagc
    42841 aaaaatcaat acatcgatgc ctttgaatgc ttcggtcatt ttttccacgg accaagttaa
    42901 atcaaaagag acatacgaaa cattctcttt ttttactaat gtttgggaag caacatctct
    42961 cacccctgca aaaatttcat gggaacttgg agctaaatct tttatcaggt gtcggccaat
    43021 ttgtccgttt gcacctacaa caaaaatttt catttggatc atcctttcga cgtcaaatct
    43081 ttccattcaa tagtaacacc aaaagagaaa aaaatcagag atcggctacg atgactatca
    43141 gttagtaaga gaagggtgct tgaagtatct taacaagaca ttgcatactg ctgcagtcgc
    43201 aagacctgcg acgattcctt caggtatacc acttgtaaaa ataaccgcta gaatagctga
    43261 ataaacagca tttaaatttg ttccgatgac tttggcataa tcttgctgga ataaaaagta
    43321 gatcatattc atcactaaaa tcgtattggt caatgaaccg gaaagtccag ctaagaataa
    43381 agaaacggaa tctgcttttt gtttcattag tttgcgcaga cctttataaa cgaaataagg
    43441 aaccacccca atcaagatgc gaggaataaa cgcgatcagc aaggctttcc agcttccatg
    43501 ttctgttccg atgactggga taaacggaga aaagacaaaa gacaaaggtg tttggataac
    43561 tgtgctacgg atcatgctga tcagtccaaa tgtaccgcca agaaaagcac ctagtcttgg
    43621 tcctaaaacg atcgaagcaa tgattacagg aatatgcatg gttgttgcat tgattggacc
    43681 gatagggata aaacctaaag gcgtaacagc taataaaatc aaaatagcta aaaacatcgc
    43741 agttaatgta aagttttttg tatttttcat aagtactcct tttttctaag catttctttc
    43801 attaagagtc agcatgacct gttcgatgat cgtctgaata tcagctaagg caccttttcc
    43861 aaaatctcca caagctaaaa gagattctct tggttcaatt tcctgatagc cgacagatct
    43921 caatgtttcc agattacgct gagtgatcgg gttttgatac atattcgtgt tcatggcagg
    43981 ggcaatcaat tttggtgttc ccactggaag cgccattgcg actgttgaaa gaagatcgtc
    44041 tgcaatgccg tttgctagct tgccgataat gtttgctgta gcaggcgcga tgagaaacaa
    44101 gtcagcttgt tttgctagtt cgatatgatt gattacctgc ggatttgatt cttgcatgac
    44161 gtctgtatgg actgcgcgct tcgacagaga ttgcaaggtt aatggcgtga taaaatgtgt
    44221 gctgctttta gacataatca catctacctg ggcacctaat ttgacgaatt gacttgtaag
    44281 atcagcgctt ttgtaagcag aaatacttcc agtaacgcct agtaagatct ttttcatttt
    44341 gattcctcca gtctaatttt ctcagtaatc aatgcagcaa tctcagattt actttgagct
    44401 tcttccactg ttccatcttt agataagaga tagccgtggt gtgtctcgcc atggatttcc
    44461 gtcaaatcat ttgcgaaaat aaaatcagtt ttgttattta tcagactatt ttttgcgact
    44521 gccagaagag attcctttgg tacatctact aatagtttga aaccaatgat ttttgctttt
    44581 ggctgccatt cacgtagata agaaatgatt tttggtgttt tcttcaaaac gagcacaaga
    44641 tgctcggtgt tagaagagat ctttgaaaca gtggtatctg tctgttcatt ttccgcaaac
    44701 caattgtcca gttcttcttg cgttgaagaa gtgggtaggt tttttgccag ctgttcttct
    44761 gaaaaactaa aagcaggagt aaaatcactg actgccatac tgtggataat cgcatcgtag
    44821 tgttcttttt tcgttagttc ttctaattgt aaaaataagt ccagtgcaga ttcgatcgta
    44881 taaatcgtta tattggagtg tcttttcggt ttcagtgctt gtttcgtagt cacgtaatcg
    44941 attgtggtat ccggattggc agctaaataa tcagctaatg cttgccctaa tcgtcctgtc
    45001 gaatgatttg taatagcacg tacttgatcg attttttcag tcgttcctcc agctgtgatt
    45061 agaatcttca tttatggtca cctacattta ctagtgttct tccttggtgt gttccagcaa
    45121 gtagtttaga tgctgtttca ggcaattgat ccagagtaat ctcttggacg accagttcat
    45181 ctgcaatctg caaatccgcc atctgttgcc ataaagaaag acgttgatct attggtacat
    45241 tgacagaatc aattccaatc aactggatgt ttcgcagaat aaaaggcaag acagtcgcgt
    45301 ttagtttgat tcccccagca ttgccacata aagctactgc accgttataa gagatcaatg
    45361 gaagaagact gcttagctgc tcgccaccta ctgtgtcgat gacatagtcg atttgctgtt
    45421 ttcctaaagc ttttgttgtc tctggcagaa attcatcagg tcgtacgact tgcaaagcac
    45481 ctagactttt tagccatgtg acagactctt cttttctgga aaaggcaatg attgactgga
    45541 atcctagttt atgtaacagg gctatcgctg tactgcctac accgccagaa gcaccagtaa
    45601 cgacaacttt tttatcggag gtcatacctt gacggattaa agcgttcaca cacaacatag
    45661 cagtaaaccc tgctgtacca aggatcatcg cttgacgcag cgtcatattt tttggtagag
    45721 gaactaacca gtctcctggt actttttgat attggctata accgcctgga tgggtgacgc
    45781 caagcccaaa accagtagca agtacaagat cttcttttga aaaacgtgga ttgttacttt
    45841 ggacgacagt tccggataaa tcaatccctg gagtcatcgg atatgttcgt atcacctgac
    45901 cagactcgct cattgccaat gcatctttat aattgacatc agaataggca atttttacca
    45961 agacttcatt ttcagccaac tcagtaaatg gcagatcact gattgctgta tggaaaacag
    46021 gttcctttat tacctgaaaa gatcgaaaag cgttcattcg tgagacactc cttttaaaat
    46081 tttcttttat cataccataa agcctactct tttattcttg ttcttccgta aatttagaca
    46141 aaaattaggt gaaaaataaa gaatcaaaca actagaattt attccaaaag ataaagaaat
    46201 attcagcaaa aaaaatttta caaagggttg cctttttcaa taaatttcgt atactaatac
    46261 gagtggtagt aaacaggaag tttactatta gaaaacttcg attcggagga aattatggaa
    46321 attggtgaga agttaagaaa tttgcgcatc caaaagaatt tgacacaaga agaactaggc
    46381 gaacgcacag atttgtcaaa agggtatatt tcccagttgg aacgagattt aagttcacca
    46441 tcaatggaaa cattcttttc tattcttgaa gtcttaggtg tgactccaga agaatttttt
    46501 catcaagaag cagcgaatct gcaagtggtt tattcaaaag aagatcatac ggtttatttc
    46561 gatgaagaaa acgggtatga attggaatgg ctcgtggctg attcgaatga aaaagaaatg
    46621 gagcctgtct tgctgacttt tgaaggtgca ggagaatata agacgtttga accttcatta
    46681 tctgaaacgt ttatttttgt attagaaggg gaattagagt taagcttagg agagacggtc
    46741 tatgtggcaa aagcaggaca gtcgatctat tatcaagcga caaaacaaca tcaattaagg
    46801 aatcatctca aaaaacgaac aaaagtattg attgttgcaa cgcaatcata tttgtaatat
    46861 agggggtaaa aacgtgggga aaccaatcat ttcatttgat caagtagtga aacgctatga
    46921 tgatgaaaca gtattaaaaa aagtaagttt tgagatcgaa caaggaaaat tttatacact
    46981 gcttggtcct tccggctgtg gtaaaacaac gatcctacgt attatagctg gattcaccga
    47041 agctacagaa ggggacatct attttgaagg gaaacggttg aatgatttgc cagctaataa
    47101 gcgacaagta aatacagtct tccaagatta tgcacttttt cctcatatga atgtttttga
    47161 taacgttgct tttggattga agatcaagaa aatgtccaaa tcagatatcg aaaagaaggt
    47221 aaaagatgct ttgcgtatgg tccagcttcc tggatacgaa aaacgggaga ttagtgaaat
    47281 gtctggtggt caaagacagc gtgtagcgat tgcacgagca attgtaaatg aaccgaaagt
    47341 attgctatta gatgaaccgt tatcggcgct tgatttgaaa ctacgtacag atatgcagta
    47401 tgaactgcgg gatctgcaac aacgattagg aatcacgttt atttttgtta ctcatgacca
    47461 agaagaagcg ttggcaatga gtgatgagat ttttgtcatg aataaaggga aaatcgtcca
    47521 aagtggtaca cccgtagata tttatgatga gccaatcaat catttcgttg ctgattttgt
    47581 tggggagagc aatatcgtgg acggtgtaat gatcgaagat aatctagttg agtttgttgg
    47641 taagcaattt gaatgtgtcg atggcgggat gcgtctaaat gaaccagttg aagttgtttt
    47701 acgcccagag gatttgacga tcacgacacc agataaagga aaactagtcg taacggtcga
    47761 tactcagctg tttcgtggtg tccattatga aatcatctgt tatgatgaac agcaaaatga
    47821 atggatggtc cattcaacga aaaaagctaa agaaggaagc aaagtaggat tggcctttga
    47881 gccagaagat atccatgtca tgcgtttcaa cgagtctgaa gaagaattcg atgcacgtct
    47941 tgacagctac gaagaatagg ggggacaaga atgaaaacaa tgcgcaggat ctattccgtc
    48001 ccttatattt tgtggctcgg tttattcgtg atcgcgcctg tattaatgat catttatcaa
    48061 tctttttttg atatgaatgg gcaattcacg ctgaataatt atctatctta ttttacgtcg
    48121 gggacatcgc tttctatgac gatcaattct gtatggtatg catttttgat cacgtttttc
    48181 acgctgatca tcagttaccc gactgcttat tttttaacaa aactgaagca caagcaatta
    48241 tggctgatgc tgattatttt gcctacatgg gtgaatctgc tgcttaaagc ttacgcattt
    48301 attgggattt tcagtgtgca cggcagcgtg aatcatttct ttgattttat cgggatcggg
    48361 ccgaaacaga tattattcac agacttcagt tttctgttcg tggcaacgta tatcgagatt
    48421 ccatttatga ttatgccaat tttcaatgca ttggaagaga tgaatccttc tttgatcagt
    48481 gctagtagag atttaggcgc gaatagcttt gagaccttcc gacgagtgat ttttccgtta
    48541 tcattaaatg gtgtgaaaag tggtgtccaa gcagtattta ttccttctct ttctttattc
    48601 atgctgactc gtctgattgg cggaaatcgg gtgatcactt taggaacggc tatcgaacag
    48661 catttcttgg ttacacaaaa ctgggggatg ggttctacaa tcggtgtgat tttaatcatt
    48721 gctatgttca tcgtgatgct cctgacaggc gagaagaaaa aaggaggtcg ctcataaatg
    48781 aaaaaattta aatggtcgta tctttattta gggatcgtct ttttattctt atatgcaccg
    48841 atcttctatc tgatttttta ttccttcaat gaaggaggaa cgatgaacag ctttacagga
    48901 tttacttggg aaaattatga agctgttttt gaagatacac gtttgatcat tatcgtattg
    48961 aatacgttca tgctggcttt cttatctgca ttgatcgcca cgatcatcgg gacatttggg
    49021 gctatgggaa tctattacac gaaaaaacga cgtgcacgga cagcgttgtt gagcatgaat
    49081 aacatcttat tagtctctcc tgatgttatt atcggtgcta gtttcttgat tttctttaca
    49141 ctactaggat tcggattagg ttttcagagt gtattgcttt cccatattgc tttcagcatt
    49201 ccaatcgtcg tcttgatggt cttgccaaaa ttgcaggaaa tgaacgattc aatggtcgat
    49261 gcggctagag accttggtgc taataatttc caagtagtca aaaatatcat tttgccttat
    49321 ctttctccag gaatcatagc tggatatttt atggcattta cctattctct tgatgatttt
    49381 gcggttacat ttttcgtcac aggaaatggc tttacgacgc tctcagtaga gatctattct
    49441 cgtgcaagac aaggaatcag tttagaaatc aatgcgctaa gtgcgttagt tttcttgttc
    49501 tccatgatat tggtcattgg atactacttt attagtaaag aaaaccgtcc aaaacggctg
    49561 aagaaaaaca gaagagtacg cgagggggtg gcacggctgc gatgaaaaaa ttacaatctc
    49621 tgtttttagg tattctcatc attattgcgg tgctgctgct tggtgttcgt caacttgaaa
    49681 aaacaagtgg catgagtgga gcaaaggtac ttaccatcta taactgggga gattatatcg
    49741 atcctagttt gatcacgaaa tttgaaaaag aatatggata caaagtgaat tatgaaacat
    49801 ttgattctaa tgaagcgatg ttcacaaaaa tccagcaagg tgggacaaac tacgacatcg
    49861 ctataccaag tgaatatatg atccaaaaaa tgatcaaaga aaaactagta cttccattag
    49921 atcattcgaa gatcaaagga ttaaataata ttgatccacg atttttagac ttggattttg
    49981 atccagataa tcagtattcg attccatatt tttggggaac tttagggatc gtatataacg
    50041 ataaattctt tgatgcaaat caaattaagc attgggatga tttgtggaag ccggaattaa
    50101 aagacagttt gatgctgatt gacggtgcac gagaagttat ggggctttct ttgaatagtt
    50161 taggctattc tttgaatagt aagaatatgg cacagctgac agaagcagca aataaattga
    50221 atcatttaac accaaatgtc aaagcaatcg tggcagatga gatcaaaatg tatatgatca
    50281 atgaagaagc ctccgtggca gtgacatttt ctggcgaagc tgccgatatg atgtgggaaa
    50341 atgaacattt acattatgtg atcccaccag aaggatccaa tctttggttt gataatatcg
    50401 ttatgccaaa aaccgtgaaa aataaagaag gtgcctatga tttcatcaac tttatgctag
    50461 aaccggaaaa tgcggcacaa aatgcagagt atattggtta ttctacacca aatgaagaag
    50521 caaaagcgtt attgccaaaa gacatttcgt cggacgaaca attctatcca tctgatgaca
    50581 cgatctccca tcttgaagtc tacaaagatc taggatcgaa atacctaggc atctataatg
    50641 acctattctt agaattcaag atgtatagga gataatggca aaactcagta agaatgggga
    50701 cttatcaacg ttctaaagag ctaaaaatcg tcctttttct atctgagttt tccaatcttc
    50761 taccaaaagc ggatgaaacg ccgctttttt tgtgttattt tattttttct accacgtttt
    50821 tctaccagag aaaagtggac aaaaccattg taaaataggg cccgagacgg gctagtaaat
    50881 ctaagattga aaaagttaca gaaggataaa gtaattggaa actatgcaaa tatacttaac
    50941 ccttctgtaa tctattaata aaactaatat atgaatccag ttcaatattt gtagctatga
    51001 aaaaacataa aaatcatatt agataaaaac taaattggta gataaattat tttgtcagat
    51061 atctgaggca aatattcgac tatttgtgtt tcaaagtaaa aattggaata caaatataga
    51121 atagacatat tgcagccgat agtttattat gcttttagac acattaaact ggaggaaaaa
    51181 atgaaaaaga gcgctaaaga tcgagttttt gatgagctga tacgactaac agggaatatg
    51241 tcttctgtca ctgccgagaa aatttcgaag aatctaggta tctctcgtca gaatgccagc
    51301 cattatttga cgagattagt ggaagataaa aaggtcgaga aattaccggg aaagcctgtt
    51361 ttgtggaagc ctttagatga atatgcggtt gtagataata cggagcaaat aaacgaagcc
    51421 tttcattctg tagttggtca tgacggaagt ctgagagagg tcattcaaaa atgtatagcc
    51481 gctgtcaaat atccgcctaa cggactcagt gtattaataa atggagccac gggtgttgga
    51541 aaaagttttt tagccacaaa aatttttgaa tacgctatcc atgagcaaat tattgaaaaa
    51601 gatgcaccat ttgctatctt aaactgtgcc gattatgcgg acaatcccga actgctttcg
    51661 gcaacactgt ttggatacaa gaagggggcc tttacggggg ctgaaaagga taccgatggt
    51721 ttattggcaa cggccaacaa cggctatctt tttctcgatg aggtccatcg cctatcgaaa
    51781 gaaaatcaag aaaagctctt tctatttatt gatactggaa actatcgtcc agtcggtgaa
    51841 aatgtaaatt ggcattctgc taaggttcgt tttattttcg ccacgacgga aaaaggtgaa
    51901 aattatttat tagacacctt tgatcggcgt attcaaatta gtgttatgtt gccaactttt
    51961 gaagatcgcc ccattcgaga acgattagag ctgattcaat tattttttca aaatgaagcg
    52021 gatgttttac aaaaagatat tattgtttca agagaagcct tgtctttaat gttatctcat
    52081 ccctttagtg ggaatattgg taagctgaag aatatcatta aaatcagttg tgcggatgtg
    52141 tatagtcgaa cacaagaaga accattaacg attgggaaaa atgagatctt gattcagtta
    52201 aatatgctgg aatccgaagt agaaagcttg ccgattgcta gtttattgat aaagaaaaat
    52261 caaaagataa aaacggatcg aatcaaaccg tttgattatg attcgatttt ggaaaaaatt
    52321 actcagctga taaatgaagg taatttcaat gaaaattttt cttcgataaa gaatgaagta
    52381 cagcatttgg tgcatcacat tgataaggat tcttttttat caatgagtag aaaattgatg
    52441 attcagatgt ttagaaaggt ctgggtatcc gttttaggaa aaacgtacgg attgacgacg
    52501 agtggacctg ttgcagaaat tattagcaga tcctatgtca tttccccaag ctataagaca
    52561 gacttaaccg ggataaatcg tacattagct gcaaatctac ctcggacgac ttacttatgt
    52621 aatcagttct tggagcattt accaccgctc tcagaaaagg acgagaactt tctaagactg
    52681 cttattgtcg tgactttatc tgattatgta gatgaatcca tcgagctgaa gggcctgttg
    52741 cttgctcacg gagatagtac ggctagcagc attcaagcag tagtgaatca attatgcggc
    52801 aattatgttt ttgaagcgtt ggatatgcca gtagagagta atgtgtcaga gattgtcgaa
    52861 tcgacaagga atttcgtgaa acggcaagtg aatacagata gtctagtgct gatcgtagat
    52921 atgggctctt taaatcaaat ttacacacag atcaagaacg atttaaaagg ggagttactt
    52981 cttctgaata atttgacgac ttccattgca cttgatattg gcttgaagat gacgatgaat
    53041 gcgccattta aacagattgc ggaggatgca gcagacaagt attcaatcaa tgttcaatac
    53101 tttgaaggct tttctcaaag tagcaacatt atcatttcct gtatgtcggg tttggggatt
    53161 tcggacaaat tgaaagatgt ttttcgtcat catttatcgg atgaatccat cgaagttttc
    53221 acgaaggact acagagaact acgtgaatta atcgaccaaa atgatgaaac ttattttgac
    53281 aagacaaaat tggtcatcac gacttcggat cttccacgtt ccttttcaat tcctaatatt
    53341 aatgtttatg acatcttaga cggtgatgga gcagccaatt tggagcatat tttgagtcct
    53401 gaaatgaagc cggcagaatt taaccgcttg attcaggagc tagtaaaatt cttttcgttg
    53461 gaaggaattg cggaccgttt gaactttctg aacccaacga tcgtgatgag tgaagtggaa
    53521 acagtcattt ctaaatatga aaattactat catttcactt taaatggccg tgtaaaacta
    53581 aatctctata tgcatacggc attgatgatg gaacgtttat tcttggctcg gacagaaaaa
    53641 tctgaagaac cgaattatga tttgaaacca gatgaagatg aattttatta tgtttctaga
    53701 agtatttttc aatcaatgga gatgaaatat aattttaaag tcaatgctta tgagctttcg
    53761 ctgctctatg aattattagg accgtatatt caaaaataaa gtgtctaaaa aagtgtctaa
    53821 tctgtttttt ttaggttaga cacttttttt aatgtgaatt aacgtgatta aaccaatgtt
    53881 tttaaaagtt ggcacaggaa ttgcttatat aaaagtgaac agaaagaaag gaattaacca
    53941 tatgaagaaa attctaatag cgactcacgg tcacttagct tcaggctttc ttagcagtat
    54001 tcaattactg acggggaagg ttcaagagat tacggtgatt aatgcttatg tggatgagtg
    54061 tgattttgaa caggagttga atgtatttgt aaaccaggtg aacgagcagg atcagatttt
    54121 tgtttttacc gatttatttg gcggaagtgt caatcagaag attaccaaaa cctttttgga
    54181 gaaagagatt gctgtaacta ttttgtctgg ctttaatctg ccaattctgc tcgaaatagt
    54241 attggcaacc aaggaattaa caaaggagga tattcaggaa ctggtaaata aatgccaaca
    54301 ggaattaaag atgaccattc ttgatgaggt acatgtagta aatgaagagg aagatttttt
    54361 ttaggaggaa gaaaaatgat taaagcagtg cgaattgatg aacgattaat tcatggacaa
    54421 gtagcgatga cttggacaaa gagtctaaat ttaaccgggt tagtagtagc aagcgatgag
    54481 gcggctacca acgatattca aaagatgaca ttgaagatgg ctgcaccatc gaatgtcaaa
    54541 gtcattatta aaacagttga tgacgcgatt catttgttaa aagatccgcg ggcgaaggac
    54601 atgcgcttga tggttttagt ccctaatgtc aaagatgcgg taaaagttgc gaaagctttc
    54661 ccaacggaaa tcgaattaat gaacgtgggg aatgctggga aaatgacacc gccatcggaa
    54721 gataagaaaa ccttatcaaa ggaagtgatg ttaacgacgt cagaaattca agacttaaaa
    54781 gaattagttg aactttatcc agataccgtt tttcagccta caccggcgat ggaaaaacgt
    54841 tcagctatct ctattttgag tgatttttag aaaaaggaag gagaaaaatt atgtatgatg
    54901 catttgtagt cgctttggcc gtttttattg gagttgctgg acatgaaatg ttcgggatgt
    54961 ccatgctgag tcgtccgatt gttgttgctc cgttagcagg agcgttgatg ggggatttgc
    55021 agacggggtt gattgtcggg gcgtcactag aagccatctt tatgggtgtc gtcaatatcg
    55081 gaatctctag tacggcggag ccttctttgg ctgctgggct ggctacagcg ttcgcaatca
    55141 aaatgggagg aaacgtggat gcgattattc ccattgtctt tccactagca gtattaggat
    55201 tacagttaat gaatatgatt ttttcttttg tatgtggacc gatggctgct aaatttttca
    55261 aatttgcaaa atctggtgat caaaaaggaa tcatcaatct gcacttcttt atgtggtttg
    55321 tccactatgc gctttatgct cttattccat tctttgccgt tttatttgga gcagatgttg
    55381 tcaaaagcgt cttggataat attccagagg tcatcatgaa cggattaaca gtcgctggaa
    55441 atctgctgcc ggcagttggg atggcgatgc tgttacggat gctttggagt aaaaatattg
    55501 ctgtgtggtt tttctttggg gccgttgtta tggcgtatct cgagttacca ttgattgcaa
    55561 ttgccgcagt tggaacgatt attgcaattg ttatagccca aagagatcta caactaaaaa
    55621 atatatctgt tcatgcagtt caaagcgatg ctgctgtaaa tgcaacgctt gaccaagaag
    55681 aggaggattt ctttcaatga aattagctga tggaatttct aaagatgaga aaaaattggt
    55741 tcggaagatg ttttggcgct cgatgactat gtatgcttcg gtgaatccgg tgacgatggg
    55801 cggcggtggt ttcgcctatt ctatgatgcc cttcattaat catttctaca aaagtgaaga
    55861 agatcgagct gcggcgctgg aacgtcatac acagtatttt tcgacgacca ttccttgcgc
    55921 gtcctttgtc atggggattg cggcatcgat ggagaaggaa aattctgaaa aagctggttt
    55981 tgacgtggaa agtatcaacg cgatcaaaac gagtttgatg ggaccattgg ctggaattgg
    56041 cgattcattg ttctggggag tttggcgtgt cgttaccgcg ggactagcga tcaacttagc
    56101 caatgccgga aatattttgg caccaattat ctttttagtt atgttcaata tacctaatta
    56161 cttgatgcga tactatggcg gcgttttagg ctattcatta ggctctaaat atattgaaaa
    56221 gctgtatgcg aacgggttaa ttgaaattct gacaaaagct gctagtatct tgggtctgat
    56281 catggtaggt gcaatgacga tcagtatggt caaattcaat accgttttga gcttttcaat
    56341 gaagggcgaa gaactaatga atgtccaaga aatcctcgat agtattttta aaggaattgt
    56401 accgttattg gtaacattga gctgtttcaa attactagat aaaaaagtcg gcgtcatcaa
    56461 aattattttt ggaatggtcg tcttgggaat tttattgtca ttacttggaa tcgcatagta
    56521 ggaagctgca gctactaggc tgcagttttt ttagcaagga gggaaaagat gactattaat
    56581 gaagtaattt attcacccaa acacccattt tttaatgctg agttaaacga cggaaatgtg
    56641 actacttcaa acgaatacag ctactatcgg aatattcctg atgtaaaggg attgaccttc
    56701 gatgtaagta atcaaaagac attagcaaac cttgatgttt gcgggacgat tcaaacgttg
    56761 accttttatc gagaaaattt actaactgag gaaaaaccag gtgtttgggt caataaacag
    56821 ctctctcaaa ccaattcgtt atccttaaag gttgaagtaa acgggattgt ctaccatttg
    56881 tcagaatcgg atcatcgtat tgaagtcgat gtgattcaag actgtttgcc tagatatatt
    56941 catcattatt cgacgtttaa ggtcattgta gtatcctttg ctcccatact ggctaataag
    57001 cgtttaagta tgcttgttca acaggtttac attgtgaatg aaacacacga aagccttcaa
    57061 gtttcagtga aagatgtgcc ttcgtatcaa gagaagtatt cggatcagca aaatgtgttg
    57121 atttctcaaa aaggaaataa ggacacgatc gcacaacagg aagtggcaag cttcgccatt
    57181 gcttttgtgg acccaaatgc ttttgaagaa gtaatgactt ttcaggaatc tgatatcgaa
    57241 aaatggctga aggaaacatt gaactatttt gctcagctat ttgggcagct gtcaatgcca
    57301 aacgatagag ttgtccatct ctatcgtcgt gcactttatc aaagcttttc tagtttcggt
    57361 atgaatcgac agggacaggt cgtcggcagc aattggggca gctatcctgc tactaatcga
    57421 atttggaata aggatatgta ttacgcatca ttgccattca ccatgtttga accggagtta
    57481 tgtcaaaaaa cggttctatg gtttgatcaa tatggcgtta agtttcctgg ttcaaaattt
    57541 acaggaggta tcaatcattc tctgagtaat tcgttatcca gtgcgttact ggctagtctt
    57601 tattttgaac atactgggga tacaaaattc tttgagcggt gtccgcaggt tctactgaat
    57661 gcttcaagaa ttattgagga catattagct caacgtcggt caggggaacc aatgcttttt
    57721 ccatctgttt ggttatcaga cgcctttgca cttggaaagt atcataccgg cagcaatctt
    57781 tgtctttgga aggcctgtat tggacttgca gaaatttttg aagccctaga acaactgagt
    57841 cttagcaagc gatacaaaaa cattgcctgt aaactaaagg aatcaatttg taaacaaatg
    57901 actatcgatg gtccttttgg tgagcaattt ttggagggaa tcggtgatga ggagaaaaca
    57961 acctattcag tgaagcacta tcaaaaaccg attcttgagc aagggttaat ctttttaagt
    58021 gatgtgattg tggatggaaa aattaattta ttgatgcatg atggagaaga atcagacact
    58081 acgttgatgc ctttttatca atttttagat aataaagatc atttatatca gaacaccatg
    58141 gccttttctg ctagttcttt caatccaacc tatagcgagg aaatcaaagg catcacttgg
    58201 ggattagaat ccggcgccac ttttcctggc tttatcactg ttttaatgag cgagctgcac
    58261 aaccctcaag ctttcgtaac ccgattagaa gaactaattt gtttggcaga tttagacggt
    58321 tcgtggtggt ggtggccgta tcgcttagag gctcaacaag gagaagtcgt gcgagacttt
    58381 ggctgcggca aatgcggctg ggcatcgggt ctttttgtca gcctaatgat cagtcaatat
    58441 ttcggattga aattcaaaaa aggagtattg caaattgatc ctgttgataa tttaacgttt
    58501 tcttggaaga atttgaagtt cggtcaagcc ttcatttcga ttgaatgtac gcaatccgag
    58561 ttgagtattt caaatttgtc agaaaagcca ttgaaaataa gtgatacgaa aaaaattctt
    58621 cacgtagaaa agggaaaaac gattcacatt caaaggagaa aaagatgagt atactaaaaa
    58681 atattaccca atttaaaaaa atccagagtc gagcaatcac tcccgaaaat ccaacaggcg
    58741 agaaaggtaa agctgcgatg ttgccaagcg agctaggacc aagccgcaaa ggtcgtggcg
    58801 caattccgct gacttctggt gaagaaactg tgattgcgga tattactgga acgggaataa
    58861 ttcgtcatat gtggatgacg attcgtgatc gaacagaatt tggcagtttt gttttacgtg
    58921 atttaatctt aagaatttat tgggatgggt cggatagccc tgctgttgaa agtcctttag
    58981 gggatttctt ttgtaatggg tttggagagc gttgcgaggt gaactcgttg ccgatagtgg
    59041 ttaatcctac agggggcttt aattcctatt tcgaaatgcc tttccaaaca tccgctaaaa
    59101 ttacgatcga gaatttacat ccgaaggata tgtcctcatt tttttatacg ataaattacg
    59161 ctttggtgga cgaattggaa gaaaatagcc tatattttca cgcaaattgg catcgggaac
    59221 gcattaccaa attacaggag gattataagt taattgatcg attaaagggt caaggctatt
    59281 acgtgggtac ttaccttgcg cttacctgcc tagaacgtta ttggtggggc gaaggcgagt
    59341 ttaaattcta cattgatggg gatagtgagt atccgaccgt aacctcaaca ggttcagaag
    59401 attattttgg cggggcgtgg gcctttcatg agtacgatga gttcggacgt ccacatgcga
    59461 aaaactattc aacagccttt ttagggtatc cttaccaatc aaatagagat gccacaagag
    59521 atcgttttga aacgggaaaa ttgaatgccg ttcatgcctt tggtgacgac gcaatgccac
    59581 gacatggtct ttatcgttgg catcttcaag accccatctg ttttaccgaa gatttatcgg
    59641 tcactttaca acaaatcggc aacgatgatg ttcgcttatt tgagcggcaa gacgatgttg
    59701 ctagtgtcgc ttactggtat tcaacagaag cttcaggaaa tactaaacgt catttcactg
    59761 atcgagaacg cttgccgcgt taatgaagtg tttttcacat attcgaaggg aggaacctat
    59821 gatgatatat ggggcaattg aagctggagg gactaaattt gtctgtgcag tcggtactga
    59881 ggaattaacg attttggaaa gagtcagttt tcccacaaca actccagttg aaacaatgaa
    59941 gcaggtcatt gattttttta aaccttttaa ggaacaattg gcaggcatcg gggtcggctg
    60001 ctttggtcca attgatattc aatgcaaatc aacgagtttc ggtcatatca catcaacacc
    60061 aaaacttgct tggcaaaatt tcaattttgt aggaacgcta aagcaatatt tcaatattcc
    60121 gattgaatgg acaacagatg tcaatgcggc ttgctatggt gaatatgttg ctggttctgg
    60181 caaagggtta gcaggtgttg catacttcac tgtgggaaca ggtatcggag gtggtgcctt
    60241 gttcaatggg actttcgtgg aagggttcag tcatccggaa atggggcata tgttgatcaa
    60301 gcgacatcca aaggacaatt tttcaggaaa ctgtcccttc caccaagatt gtttagaggg
    60361 gatggcagca ggaccagcga ttgaaaaacg gttgggtgta aaaggccaga atttattggc
    60421 tgacgattcg ttttggcaga ttgaagcctt ttaccttgcc caatgtgcat acaatacaac
    60481 actgatgttt tcgccagata gaattatttt tggcggtggt gtaatgaaac aagaacacat
    60541 gaagaaaaaa gttcaggata aatttgttga gcttataaat ggatatgttg aaataccacc
    60601 aattgatagc tacattatta cgcccgaatt aggtgataat gccggaataa tcggcggatt
    60661 agcattggcc agaaaagcgg taagaaataa gcaaccataa ttaatgaatg tttcattgat
    60721 actcatgtca aaagtattta accgagtaat caaatgatca aatgaagttg gataaagcga
    60781 aaatgaattc aaataaaaag gctctaagtc aaatcgtgtt gttttcatta aatcactgaa
    60841 aggaaatgct tctgcgtttc cttttttctt tttgttgtgc gctgtatacc ttgaggatat
    60901 tcactggtgg cgtacactta aatagtaata tattgtgtta ctttatgtct gtggtaatag
    60961 ttatagttgc ttaccaatgt atgttcattt ttcgaaatgt tgacttcata atccttggct
    61021 taatgtttga atttttttgg tgatagattt tttcagccgt ataaaataaa tcgtaattct
    61081 attatagaga gttgtgatta taaaaagata gcaagaaaaa aaaagaaagt ttctatac
//
LOCUS       DASHWW010000010        56528 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.010, whole genome shotgun sequence.
ACCESSION   DASHWW010000010 DASHWW010000000
VERSION     DASHWW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.010"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(592..1983)
                     /locus_tag="U2R64_000757"
     CDS             complement(592..1983)
                     /locus_tag="U2R64_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HEM8917598.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2196..2582)
                     /locus_tag="U2R64_000758"
     CDS             complement(2196..2582)
                     /locus_tag="U2R64_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEM8917599.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2638..3261)
                     /locus_tag="U2R64_000759"
     CDS             complement(2638..3261)
                     /locus_tag="U2R64_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEM8917600.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3325..3993)
                     /locus_tag="U2R64_000760"
     CDS             complement(3325..3993)
                     /locus_tag="U2R64_000760"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEM8917601.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4005..4445)
                     /locus_tag="U2R64_000761"
     CDS             complement(4005..4445)
                     /locus_tag="U2R64_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917602.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4504..5175)
                     /locus_tag="U2R64_000762"
                     /pseudo
     CDS             complement(4504..5175)
                     /locus_tag="U2R64_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5360..5758)
                     /locus_tag="U2R64_000763"
     CDS             complement(5360..5758)
                     /locus_tag="U2R64_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HEM8917603.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5755..6528)
                     /locus_tag="U2R64_000764"
     CDS             complement(5755..6528)
                     /locus_tag="U2R64_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEM8917604.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6525..7208)
                     /locus_tag="U2R64_000765"
     CDS             complement(6525..7208)
                     /locus_tag="U2R64_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEM8917605.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7375..8262)
                     /locus_tag="U2R64_000766"
     CDS             complement(7375..8262)
                     /locus_tag="U2R64_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8917606.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8259..9128)
                     /locus_tag="U2R64_000767"
     CDS             complement(8259..9128)
                     /locus_tag="U2R64_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8917607.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9265..10551)
                     /locus_tag="U2R64_000768"
     CDS             complement(9265..10551)
                     /locus_tag="U2R64_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8917608.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            10824..11402
                     /locus_tag="U2R64_000769"
     CDS             10824..11402
                     /locus_tag="U2R64_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEM8917609.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11402..12331
                     /locus_tag="U2R64_000770"
     CDS             11402..12331
                     /locus_tag="U2R64_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8917610.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12328..14064
                     /locus_tag="U2R64_000771"
     CDS             12328..14064
                     /locus_tag="U2R64_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEM8917611.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14127..14963)
                     /gene="pheA"
                     /locus_tag="U2R64_000772"
     CDS             complement(14127..14963)
                     /gene="pheA"
                     /locus_tag="U2R64_000772"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEM8917612.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(14960..15469)
                     /locus_tag="U2R64_000773"
     CDS             complement(14960..15469)
                     /locus_tag="U2R64_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEM8917613.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15462..16757)
                     /gene="aroA"
                     /locus_tag="U2R64_000774"
     CDS             complement(15462..16757)
                     /gene="aroA"
                     /locus_tag="U2R64_000774"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEM8917614.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(16770..17861)
                     /locus_tag="U2R64_000775"
     CDS             complement(16770..17861)
                     /locus_tag="U2R64_000775"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEM8917615.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(17878..19044)
                     /gene="aroC"
                     /locus_tag="U2R64_000776"
     CDS             complement(17878..19044)
                     /gene="aroC"
                     /locus_tag="U2R64_000776"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEM8917616.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19046..20110)
                     /gene="aroB"
                     /locus_tag="U2R64_000777"
     CDS             complement(19046..20110)
                     /gene="aroB"
                     /locus_tag="U2R64_000777"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEM8917617.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20143..21165)
                     /gene="aroF"
                     /locus_tag="U2R64_000778"
     CDS             complement(20143..21165)
                     /gene="aroF"
                     /locus_tag="U2R64_000778"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEM8917618.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(21824..22798)
                     /locus_tag="U2R64_000779"
     CDS             complement(21824..22798)
                     /locus_tag="U2R64_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HEM8917619.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(22779..24662)
                     /locus_tag="U2R64_000780"
     CDS             complement(22779..24662)
                     /locus_tag="U2R64_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HEM8917620.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24680..26905)
                     /locus_tag="U2R64_000781"
     CDS             complement(24680..26905)
                     /locus_tag="U2R64_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEM8917621.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27020..28054
                     /locus_tag="U2R64_000782"
     CDS             27020..28054
                     /locus_tag="U2R64_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8917622.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28121..29134)
                     /locus_tag="U2R64_000783"
     CDS             complement(28121..29134)
                     /locus_tag="U2R64_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8917623.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29212..29400)
                     /locus_tag="U2R64_000784"
     CDS             complement(29212..29400)
                     /locus_tag="U2R64_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HEM8917624.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(29840..29968)
                     /locus_tag="U2R64_000785"
     CDS             complement(29840..29968)
                     /locus_tag="U2R64_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEM8917625.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(29971..31344)
                     /gene="rlmD"
                     /locus_tag="U2R64_000786"
     CDS             complement(29971..31344)
                     /gene="rlmD"
                     /locus_tag="U2R64_000786"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEM8917626.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31455..32510)
                     /locus_tag="U2R64_000787"
     CDS             complement(31455..32510)
                     /locus_tag="U2R64_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEM8917627.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32520..33950)
                     /gene="gatB"
                     /locus_tag="U2R64_000788"
     CDS             complement(32520..33950)
                     /gene="gatB"
                     /locus_tag="U2R64_000788"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEM8917628.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(33947..35419)
                     /gene="gatA"
                     /locus_tag="U2R64_000789"
     CDS             complement(33947..35419)
                     /gene="gatA"
                     /locus_tag="U2R64_000789"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEM8917629.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35419..35724)
                     /gene="gatC"
                     /locus_tag="U2R64_000790"
     CDS             complement(35419..35724)
                     /gene="gatC"
                     /locus_tag="U2R64_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEM8917630.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(35830..37866)
                     /gene="ligA"
                     /locus_tag="U2R64_000791"
     CDS             complement(35830..37866)
                     /gene="ligA"
                     /locus_tag="U2R64_000791"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEM8917631.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(37883..40117)
                     /gene="pcrA"
                     /locus_tag="U2R64_000792"
     CDS             complement(37883..40117)
                     /gene="pcrA"
                     /locus_tag="U2R64_000792"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEM8917632.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40272..41831
                     /locus_tag="U2R64_000793"
     CDS             40272..41831
                     /locus_tag="U2R64_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEM8917633.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(41942..43873)
                     /locus_tag="U2R64_000794"
     CDS             complement(41942..43873)
                     /locus_tag="U2R64_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8917634.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(43891..44805)
                     /gene="pfkB"
                     /locus_tag="U2R64_000795"
     CDS             complement(43891..44805)
                     /gene="pfkB"
                     /locus_tag="U2R64_000795"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEM8917635.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(44802..45554)
                     /locus_tag="U2R64_000796"
     CDS             complement(44802..45554)
                     /locus_tag="U2R64_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8917636.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(45713..45922)
                     /locus_tag="U2R64_000797"
     CDS             complement(45713..45922)
                     /locus_tag="U2R64_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917637.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(45933..47261)
                     /locus_tag="U2R64_000798"
     CDS             complement(45933..47261)
                     /locus_tag="U2R64_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917638.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47397..47552
                     /locus_tag="U2R64_000799"
     CDS             47397..47552
                     /locus_tag="U2R64_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917639.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(47626..48213)
                     /locus_tag="U2R64_000800"
     CDS             complement(47626..48213)
                     /locus_tag="U2R64_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEM8917640.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48296..49546)
                     /gene="clpX"
                     /locus_tag="U2R64_000801"
     CDS             complement(48296..49546)
                     /gene="clpX"
                     /locus_tag="U2R64_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEM8917641.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(49793..51082)
                     /locus_tag="U2R64_000802"
     CDS             complement(49793..51082)
                     /locus_tag="U2R64_000802"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEM8917642.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51236..52168)
                     /locus_tag="U2R64_000803"
     CDS             complement(51236..52168)
                     /locus_tag="U2R64_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917643.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52325..52984)
                     /locus_tag="U2R64_000804"
     CDS             complement(52325..52984)
                     /locus_tag="U2R64_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEM8917644.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(52987..54012)
                     /gene="sppA"
                     /locus_tag="U2R64_000805"
     CDS             complement(52987..54012)
                     /gene="sppA"
                     /locus_tag="U2R64_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HEM8917645.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54025..54315)
                     /locus_tag="U2R64_000806"
     CDS             complement(54025..54315)
                     /locus_tag="U2R64_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917646.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            54724..>56528
                     /gene="glmS"
                     /locus_tag="U2R64_000807"
     CDS             54724..>56528
                     /gene="glmS"
                     /locus_tag="U2R64_000807"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEM8917647.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
BASE COUNT        15805 a        12166 c        10040 g        18517 t
ORIGIN      
        1 ctgttctaac attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag
       61 ctctcaacag aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt
      121 ttttgttatt tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata
      181 aaaaaagagg tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca
      241 actcctcggt cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct
      301 ctttgtgact cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag
      361 cttgcatctg cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg
      421 ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag
      481 aagtagcttc tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa
      541 acttcttctt atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt
      601 cacatcgatc actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc
      661 acttgtcacg ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc
      721 gattaatggt tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc
      781 taaaacgatc agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact
      841 gattgttaca attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc
      901 tgctggtgcg acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc
      961 aatagacaaa ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt
     1021 tgtctgagtc tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa
     1081 gctcaatacc ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa
     1141 aatcagtgag tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt
     1201 acctaaattg acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa
     1261 tactccataa ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag
     1321 actgtcgact aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag
     1381 ataagcgatt ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact
     1441 acctgctaaa tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga
     1501 taagttttca actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc
     1561 tccttgtgtg aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa
     1621 tgctgcaata gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag
     1681 cttttcagaa actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat
     1741 aactagcatt tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga
     1801 ttgagtaacg actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat
     1861 accaactcct aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg
     1921 atagaacaca tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt
     1981 catttttctc ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga
     2041 gaatgattct tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac
     2101 gatttttatc gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg
     2161 atagctttaa tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa
     2221 ttcaatttta ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt
     2281 acgatatcga ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga
     2341 ccttcaattt tccgattgag gatatgattg atctgactca cacttccaga taaaacatat
     2401 gtatcaaaca ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag
     2461 ttttcgatcg tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg
     2521 ttcggcaatc tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc
     2581 atataatttt atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta
     2641 ctttttaatg atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc
     2701 cgggatctca cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt
     2761 ccctgcttcg atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg
     2821 aaaagtatcg atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc
     2881 gatccctact acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt
     2941 tgattctgtc aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc
     3001 cagtacttgt ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg
     3061 gtgaaataat tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt
     3121 agaatacttt ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt
     3181 tagtgcttgc catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa
     3241 gtcccatata taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct
     3301 ctcactttta gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc
     3361 tgctaatgta tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc
     3421 aggaacatct tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag
     3481 taaatcttgc cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg
     3541 attcactgtc atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata
     3601 tctgcggtca aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca
     3661 tgtttttact tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag
     3721 atccccataa tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc
     3781 catttcttct agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac
     3841 ggcatcgaat tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt
     3901 tcctttttct gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc
     3961 gctttcgcca tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg
     4021 aattttatac cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc
     4081 tgcttttgat gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact
     4141 tgctttttgt tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa
     4201 cgttgattct catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat
     4261 ccgaaaaaga cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa
     4321 ctaaagacaa gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt
     4381 ccctgcataa gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc
     4441 atcatattat ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa
     4501 gccttaattg gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc
     4561 aatcacaatc actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg
     4621 aagaaacagc ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat
     4681 caattgagga aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt
     4741 cgttttgatc agattccgtt ttttactgat cactttttaa aagcttttta gaatcttttg
     4801 ctgacgtcta aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg
     4861 cagttctgct gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg
     4921 aaacagttca accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac
     4981 tggtaattcc aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata
     5041 gatttctcct aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt
     5101 attttcctgc aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac
     5161 aactaaaaaa ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa
     5221 aagaaagtct gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac
     5281 gagaaaaata caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat
     5341 ttcctcttca aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa
     5401 gttcttgcat tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt
     5461 ctacatcaat actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa
     5521 tcgcatccat tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt
     5581 ctggcgaaat gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat
     5641 gtaagatcgt tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca
     5701 ttcctccgtc aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt
     5761 gctttccccc aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt
     5821 ataaatatat cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac
     5881 accaaacccg tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat
     5941 tgataaaata aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat
     6001 tgctaaaaag atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat
     6061 caagaaataa taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc
     6121 gccgatccca attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa
     6181 ttcttcaacc tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc
     6241 cattaaaaag ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc
     6301 taaatgctgt cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc
     6361 aatagtcgtt atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa
     6421 actaatgata ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc
     6481 catggtaacg atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc
     6541 cccaaaatca tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg
     6601 tcattttcat ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata
     6661 aatggaacag ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat
     6721 tcggaactgg tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga
     6781 taataggata gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg
     6841 acgctgacga tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact
     6901 tgttgtccca aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat
     6961 cccaaactga ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct
     7021 ccgacttcca tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg
     7081 attgccgcac caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac
     7141 gttaaaatga caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt
     7201 tttagcatgt atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga
     7261 gcacaaactt aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa
     7321 agtatctttt tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt
     7381 tacagagccg atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt
     7441 tggtaaagta gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc
     7501 acccatagca gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa
     7561 gggccataaa taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt
     7621 atttttagcc gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa
     7681 tcgagcggct tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat
     7741 caaaaaagca gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac
     7801 cgttccgttc aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac
     7861 catcatcgat agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc
     7921 aaatccatat cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat
     7981 catcgctgaa ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa
     8041 attgatgatc aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt
     8101 cgtcattccc aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa
     8161 tgctgtatac tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac
     8221 gttggggcgt tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact
     8281 ttcgtttgga ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc
     8341 gcatatccaa aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg
     8401 gtcgttgcat ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat
     8461 gtcccgatcg tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc
     8521 actttgataa actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc
     8581 gaatcaatat tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa
     8641 gtgatcgaaa gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt
     8701 gtgtcaatca taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga
     8761 cttttcatga tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt
     8821 cgaaacaacc ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct
     8881 agaaacaaca tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt
     8941 ttaaaagttg catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg
     9001 acagggggac cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg
     9061 attgatatca aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc
     9121 tgcttcattc ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga
     9181 caatatctgt aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga
     9241 agaaattcac ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt
     9301 atctgctagt accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac
     9361 gactgcttca attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca
     9421 tgttgaaaaa tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc
     9481 ttcttgttca ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc
     9541 catcagttct tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc
     9601 agctactcct ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg
     9661 cagattttct ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc
     9721 tccttggatc gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg
     9781 tatcgcagtt actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag
     9841 agtggcaaac aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc
     9901 cccatcttca gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag
     9961 gtcagaagga ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac
    10021 ttgaatatac tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc
    10081 catcagatcc gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat
    10141 tttatctcct actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat
    10201 agcagacaaa ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc
    10261 ttcaatcaag acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag
    10321 tttctgaacg atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc
    10381 ataaactttt tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac
    10441 agtgactttt tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc
    10501 tgatgctgcc gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg
    10561 ctccttttcc atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa
    10621 cggtttcttt attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa
    10681 tcaactatga caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt
    10741 ctttaaaata aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga
    10801 ctattcttaa ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga
    10861 cgattttaga tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag
    10921 ggactttttc cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg
    10981 tggtcacaga tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac
    11041 agcaacaacc tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta
    11101 aagattcttt taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt
    11161 tttttctaaa ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc
    11221 caatcaccaa tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa
    11281 ctcgtccatt gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga
    11341 aaaacggcca ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt
    11401 gatggatagc gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg
    11461 ctatgtaatc aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca
    11521 agaagttttt ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa
    11581 tgaaatattc caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa
    11641 gaaccttgct tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag
    11701 tagttattta acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa
    11761 tttcttcacg acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat
    11821 caatcgtttc tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact
    11881 ttctttgctc aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt
    11941 ttctattctt gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa
    12001 agacaatttc gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga
    12061 aatcaattta caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat
    12121 ctttactgaa aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa
    12181 agccaagctc tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg
    12241 ctataccgaa ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc
    12301 tcaataccgt aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt
    12361 gccaaacttc tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg
    12421 tttatttatc atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg
    12481 gtactaaaaa agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta
    12541 gccgcttttg attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat
    12601 atggaacagc ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc
    12661 catccaatga tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga
    12721 aacgacatgc tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga
    12781 gtgaatgaac gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc
    12841 gataagaaag cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt
    12901 tacggatatg ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta
    12961 gtaaatcctg agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca
    13021 aatgaagaaa atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa
    13081 acaacgattt caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca
    13141 ttactcagtc aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt
    13201 attttgtata atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat
    13261 cgacacacaa aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc
    13321 ttaaaagcta ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc
    13381 aatcaattgc taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag
    13441 aaacgttcgc ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat
    13501 acgctgacta gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga
    13561 atcgacagtt tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca
    13621 gtcaaggaag aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc
    13681 gaaagaatct cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat
    13741 atgatccttc aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa
    13801 ggattcatca cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat
    13861 aacggcgatg gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc
    13921 ggcatcagcc atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg
    13981 atccaatcag tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa
    14041 aatcaatcag aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta
    14101 aataaatcaa tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga
    14161 taacagccca atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct
    14221 actaatgtca ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta
    14281 gttttcaatg gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc
    14341 agcattttat gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt
    14401 actggagctg actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg
    14461 ttcaactcat tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt
    14521 tctaatgaag caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca
    14581 gcagttgttg attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt
    14641 tgtgattgtg ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg
    14701 cctaaaagct gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt
    14761 ttggaaagaa gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg
    14821 acagccagat cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac
    14881 gcagtcaatt gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct
    14941 ggccctagat agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct
    15001 tttctggtgt ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa
    15061 gtcgttgtgc caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa
    15121 tagacgtttc atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa
    15181 gaacaatcgg ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac
    15241 cagtcgcgat aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc
    15301 gaaagctttt ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct
    15361 caatctttgt atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga
    15421 ttgttgtttt tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct
    15481 cctgacacaa gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca
    15541 gctccttcta gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg
    15601 attcgatgat cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg
    15661 atcagaccgt ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc
    15721 gcatcaattc tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt
    15781 ccttctgctt gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg
    15841 atttctccac caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat
    15901 tggttctgtt cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct
    15961 aagataccag ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga
    16021 acaagaagtc ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc
    16081 tgttgaccag ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc
    16141 cttccgccaa attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg
    16201 attacggatg tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca
    16261 ctggctacag gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt
    16321 ggtagatact ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc
    16381 atcactcgcc ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa
    16441 ggctgtccag ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca
    16501 attgattcgg ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct
    16561 tcctcttctt cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct
    16621 tctgcgcgca aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg
    16681 ctgcgatggg aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt
    16741 tgttgtaata attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta
    16801 gacataatga ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt
    16861 attcctaaaa tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct
    16921 tttccgatca gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat
    16981 aaatcaaaaa aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct
    17041 tttgcccgat tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct
    17101 atttgtgtca tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc
    17161 aacaaaatat ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag
    17221 cctcctgctg ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg
    17281 actaagccag ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt
    17341 tctcttgctg taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt
    17401 tcaacatctt ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt
    17461 ttagcatctg ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca
    17521 aaccgaagat ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc
    17581 gtaatgatga cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt
    17641 gtacggacgg gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca
    17701 cttgcaacgt aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta
    17761 tcccaaccaa ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca
    17821 ccaatcagtc caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta
    17881 gtaatgtttc aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc
    17941 acttgggaat tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac
    18001 gacgctagct gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc
    18061 ttttgtatcg atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac
    18121 cccgcgaatg acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt
    18181 ggtacgtcgg aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc
    18241 tggtaatgaa ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact
    18301 aaccacagct tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa
    18361 tccagctgga acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt
    18421 ctttgtctga tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac
    18481 ttctgacgct tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc
    18541 ttggattcca ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat
    18601 tttcttggca attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc
    18661 aagcacattc cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc
    18721 tggacgcgga cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga
    18781 catgacagtt gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc
    18841 aattgttttg ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat
    18901 ccttcctcct ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc
    18961 tgacagaggt aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga
    19021 ttctcccgca gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg
    19081 tgggaacagg aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc
    19141 ttcctcttgc tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat
    19201 cgtacgtaat cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag
    19261 ttggagacaa gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc
    19321 cttctccatg actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat
    19381 gaccaaaatt taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc
    19441 gtttgatttc caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt
    19501 ctttcagctc gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga
    19561 tttcagcgat tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa
    19621 tcaatacacc agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga
    19681 ctgctgtctt cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa
    19741 cgaaatggat cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc
    19801 ctccaccaag tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt
    19861 ataactcagc tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga
    19921 ctggttcaaa attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa
    19981 cgtttgtatc agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc
    20041 cagcctgttc tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta
    20101 cagtaagcat tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat
    20161 cttttccatt gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc
    20221 attcaacgat tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat
    20281 catgccatct gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat
    20341 tcctgtacca tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg
    20401 gacagcactt aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc
    20461 gataaaaatg acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc
    20521 attgatcgta ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc
    20581 agatagcagt ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc
    20641 agccaccata tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc
    20701 atcagccgct tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg
    20761 agaagtacgt ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat
    20821 tcgcgcacat tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac
    20881 gaaactgccg tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa
    20941 ttctcgagaa gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata
    21001 gcgtgtaaat gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg
    21061 ttctgttcct tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt
    21121 ttttatttgt tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt
    21181 cttttgttta cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt
    21241 aattcctact aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat
    21301 gacccagata atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc
    21361 ttcaacgagc cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc
    21421 tacgtggctg taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt
    21481 ttgtacccac gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca
    21541 gttttgtaag ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc
    21601 tagtatagac ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct
    21661 gatagttaac tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg
    21721 aacaaaagta tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct
    21781 ttgtcttgta aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc
    21841 cgatttcatg gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc
    21901 tattgatacc cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg
    21961 gcggtagttc ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg
    22021 aaaaagcaaa tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat
    22081 ccgtattatc caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc
    22141 cgcattcttg gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt
    22201 cgacaccacc agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa
    22261 attttgcttt cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt
    22321 tttgtccata ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa
    22381 ttgtcacttg ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt
    22441 cagcgtattc attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt
    22501 tattgtccac cagtacttct atttctttga cttttggata caatccggct cctaaccaca
    22561 taccggattt aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa
    22621 ctggaagtgt ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc
    22681 ctcttgtata agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc
    22741 cgaagacgat tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa
    22801 taatatctta cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc
    22861 cctgagaatt catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct
    22921 ctgcctgtga ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct
    22981 ccttggtaca tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa
    23041 ttccccatgt catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg
    23101 tagtcaatga tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct
    23161 tcgaatgctg gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt
    23221 ttgaagtaat cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac
    23281 caaaaaagaa tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga
    23341 acagccgcct gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc
    23401 attttttgcc atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct
    23461 tggtcgcata aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg
    23521 atctttgcat tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt
    23581 ccttttttcg gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg
    23641 aagtagatga ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac
    23701 tccgttactc ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga
    23761 aaatgccccc acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt
    23821 aacggatatt gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc
    23881 tgactgtttt tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat
    23941 ttgtcatcta agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact
    24001 aagaagacat ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca
    24061 gctgtacttc ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt
    24121 aaatcaaatt cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac
    24181 caaataaaca ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga
    24241 ccttcttcta atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa
    24301 aagatccctt ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt
    24361 ccctcccacg gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata
    24421 tgactaggaa cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt
    24481 tttggtcgta ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt
    24541 ttaagggagg atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt
    24601 gcatttgatt ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc
    24661 atactttttt ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac
    24721 cttgaaaatc ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct
    24781 tcgaggtctg ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga
    24841 acgctggttg agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag
    24901 gagacacaaa catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat
    24961 ggccatactg gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct
    25021 tttcttcttc aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag
    25081 ctgtttctcc tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg
    25141 atacatgagc tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca
    25201 tacgctccac tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc
    25261 cggcatcaaa ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag
    25321 ttgtcaaatg ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt
    25381 gtctctgtgg gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt
    25441 tgatgtagtc aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc
    25501 gaacatctaa ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac
    25561 ctggctcctg cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca
    25621 tttcaggttc aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt
    25681 cacgtaatcc atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt
    25741 ccgcatctct ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct
    25801 ttgcttcatc aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc
    25861 agttattgac cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac
    25921 gtagcaactc atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga
    25981 tcatttcagg tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt
    26041 tgatcccacc gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt
    26101 tgccggaata aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat
    26161 gaactaaagc aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata
    26221 cttttgttcc agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg
    26281 gcaaagcaat gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg
    26341 ctttttctag tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca
    26401 ctgctctatc agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct
    26461 taagtgaaat caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc
    26521 cttcgatctc tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt
    26581 ctgatccatt cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag
    26641 aagagtattc ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat
    26701 ttcctgaaaa tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg
    26761 gtttgccaaa ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa
    26821 gaaatgtatt tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat
    26881 ctgtttttct atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt
    26941 ttttttataa ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt
    27001 ttttgaggag tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc
    27061 tcctgctaca gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac
    27121 tcggcaacgg atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata
    27181 tatcaaaaag agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga
    27241 acaggatatc tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca
    27301 tttagggatg aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga
    27361 tcagttaggt gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt
    27421 aaaacaaaac atgcaaatag tcgtcgtgga taaccctgac atccaacaag aggtcgatat
    27481 ggtgtatgca gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg
    27541 tcataaaaga atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa
    27601 gcagatttct ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca
    27661 cttagaaaaa tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact
    27721 tgcgactaat ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga
    27781 tccaatggca attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga
    27841 gattgttgta gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac
    27901 cagtgttcaa atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg
    27961 aattgacggt atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag
    28021 ggaaagtttt atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg
    28081 tttcttcata ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa
    28141 aatccaatgt ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt
    28201 catgggtaat ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt
    28261 ctgtcaaccg attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag
    28321 ttatatacgt tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt
    28381 gctcactcgt tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa
    28441 acttcataaa tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc
    28501 aataagaaat ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt
    28561 tagcatacgc atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac
    28621 tatctccacc aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta
    28681 ataaatcttt gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg
    28741 ctaattcata attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa
    28801 attctttgac acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa
    28861 caggaacagg ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact
    28921 tggactcata cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt
    28981 ttttatcagt gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc
    29041 tgggggaaag ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga
    29101 accatccgat aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa
    29161 gcattctgat tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt
    29221 ttccccaaac ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa
    29281 caaaacattt tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc
    29341 caaaggcaga tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat
    29401 ttcgccattt ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct
    29461 ctaaaagaac aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat
    29521 tttcttgagt aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg
    29581 aataataatt tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa
    29641 taaaaatctt tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa
    29701 tgacgttcat tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc
    29761 gccaaaataa tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct
    29821 tagtctttct ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac
    29881 gatcattctt aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca
    29941 attctttcat tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa
    30001 ttcgatatga tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc
    30061 tgcttctgca aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac
    30121 gattcgttct ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg
    30181 tggagggtca actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac
    30241 tttttctgct tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa
    30301 ctgtgcatct tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc
    30361 tgctaaagac aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt
    30421 atctaactcg gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac
    30481 ttgataaaat gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata
    30541 gtctctgcca tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt
    30601 gatattttgg atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc
    30661 cttggattta aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata
    30721 atgaccacga cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc
    30781 tcgtacttgg aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg
    30841 atcttggata taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc
    30901 ggtggctaac tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa
    30961 tggttctgcc attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc
    31021 cattacatgc tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc
    31081 taaaggtgcg atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga
    31141 ttgtgtaata aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag
    31201 tatttctact tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt
    31261 tgctaccccc attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt
    31321 ctttactatt tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg
    31381 aactctacta taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca
    31441 gcaccggctt ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg
    31501 tcgatatctt catccgttaa acgttcgact tcttttacga attctttgct gacaacctct
    31561 aattcttctt catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag
    31621 aactcaatgt gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca
    31681 tctaagttga tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt
    31741 gttttggtat agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct
    31801 gcaatatgca agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca
    31861 tcatccaatt tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct
    31921 aggaaaaaca tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg
    31981 attggcttta ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa
    32041 atactcttta gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg
    32101 atattgatga agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt
    32161 tttatcactt ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag
    32221 tcgttcgttg taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt
    32281 ccattaacca cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct
    32341 agttctgcga ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag
    32401 gcgctggctt caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc
    32461 aataattctt ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc
    32521 tatcgtttcg ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct
    32581 ttagttgctt tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg
    32641 aaatcatcga cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg
    32701 ttcggatcag ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca
    32761 tttgtgatca attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg
    32821 atcaaacgaa tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt
    32881 ttctcactgt tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca
    32941 tctgcaccat tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat
    33001 accattgcgt catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct
    33061 ggcatctcag gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc
    33121 gggatatcag gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa
    33181 actgttttat tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa
    33241 agaagaactt ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa
    33301 gagttcaagt ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga
    33361 gaaatattgg catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta
    33421 aattggataa ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata
    33481 tcagcttcag aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa
    33541 taaccgccaa taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc
    33601 cggatttttt tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt
    33661 tgatcaaatt gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg
    33721 tcaaaatgag tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat
    33781 tccagcgcag ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt
    33841 gtattgctgt ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg
    33901 gtttttaact cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc
    33961 ctcctaaaat agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg
    34021 cttgatacat cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc
    34081 cttctgataa acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg
    34141 ttaagatgtc actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg
    34201 caactgttgg tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat
    34261 ctcgtttgat caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg
    34321 cgcttaagga gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg
    34381 aacgtgagtt gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc
    34441 ggataccatc gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa
    34501 cagccacacc gtattttgaa tgaggcaagc tgacttcttc cacaacagca cctaatgaac
    34561 ggaatgtttc tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta
    34621 agtattcttt aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa
    34681 aatcaggaac tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg
    34741 tcaatgctaa tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg
    34801 aagcaaaggc aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga
    34861 tgccgttaaa agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg
    34921 gaatttgtcc agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg
    34981 ttgggtccca agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag
    35041 caaattcatc catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca
    35101 tgaccgttgc atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca
    35161 agatatcttt tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc
    35221 tttcatcaat ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca
    35281 atgtaatgaa tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg
    35341 tcaaatcttg tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac
    35401 gattgtgtaa ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt
    35461 gataaagccg tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc
    35521 ttgcgcccga tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac
    35581 accttccgta tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc
    35641 ggtaaaactt gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt
    35701 cacttgttct tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc
    35761 tctctatttt aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa
    35821 actcattttt cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc
    35881 tgtccaaact tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc
    35941 tgctaccacg atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc
    36001 gatcgtctct tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt
    36061 tttttcttta aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc
    36121 gaaattgacg cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa
    36181 ataagtgact acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc
    36241 atagtcactt ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc
    36301 tttcgctccg acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt
    36361 gctgttgtcg attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt
    36421 caataactct tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc
    36481 atacatctgt tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac
    36541 aaagtggttc aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc
    36601 tacttcttca tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg
    36661 gtattcttcg ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat
    36721 gtctcccgct ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata
    36781 atcaccgtta tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat
    36841 gatagctgtt ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag
    36901 cgtttcaact tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt
    36961 aaaaccaagt tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc
    37021 atagggcaaa tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat
    37081 cgaatgacat agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag
    37141 cgcatcatac tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt
    37201 gtccagattt cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc
    37261 gttccgagga ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac
    37321 aaatgaccgt tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa
    37381 tttgattggg accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc
    37441 atccccgcga gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag
    37501 tccatctatt tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg
    37561 ttgatcaaaa gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat
    37621 atcatgagtg actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga
    37681 atcagacgtg atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt
    37741 atcataaaca tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg
    37801 gttcagtctt gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg
    37861 ttccatcatt taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac
    37921 gttttactcc ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta
    37981 ctcggacgac tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc
    38041 tgttattttc ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat
    38101 agctatatgc tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt
    38161 cgatttccag taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg
    38221 tccgtccata taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg
    38281 tgatccccac atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc
    38341 gagataaagg aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc
    38401 ctttggctgc atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa
    38461 tgtcggaaac aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag
    38521 cgtcttcttc attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt
    38581 cctccaagtt ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta
    38641 gatatccgct acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca
    38701 tctgagtgac ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac
    38761 cgatatttgc cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag
    38821 caaaactgcg tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga
    38881 tacgctcaaa actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat
    38941 ctttgatttc tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg
    39001 ctttcaacag agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa
    39061 agtcgccgta attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac
    39121 gggtttcgtc tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt
    39181 ctgtccacaa gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc
    39241 taaggatgtt tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat
    39301 aatctttttc aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt
    39361 gatctgcatc tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg
    39421 tatactgtgc gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt
    39481 gataatacgt gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt
    39541 cgtcaaagtc catacattga ttatattgaa gctctttttg gtaagcagca taacattttg
    39601 ccgcaatctc ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc
    39661 tgttttttgc ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa
    39721 tgttcagttc ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg
    39781 taaagttccg gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg
    39841 agtgaaaagt cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt
    39901 ctttcatttc ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga
    39961 cttctttttc ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc
    40021 ctgcacctgc cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg
    40081 ggttcatccc gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca
    40141 atcttgttaa ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg
    40201 tttcttttta tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc
    40261 gaggcgtttg aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt
    40321 ttattctaaa aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat
    40381 tatctatcga aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc
    40441 cgatttactt aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc
    40501 tggtcaaaaa tgaaccggat atcaagggaa gcgggattcc acaagtagtg ggacagcttc
    40561 gcggggaatt atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac
    40621 tttcagttgg tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat
    40681 ccattggaca aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa
    40741 tttctagcgg tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac
    40801 tctttgtttt agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg
    40861 cttcagcaat cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat
    40921 atctaggtga ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag
    40981 tacttctagg catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt
    41041 acaaccgatt gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc
    41101 caattggtta tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg
    41161 gacatgcttc cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt
    41221 ccatgatttc ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg
    41281 gggctttaat cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct
    41341 acatcaagga ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac
    41401 cgctgacagc aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt
    41461 taggattggc tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt
    41521 acgaatcatt attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa
    41581 ggacaacttt tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag
    41641 acttcaattg gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct
    41701 tgactcacgg tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag
    41761 caaacttgcc aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc
    41821 aatcatttta acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga
    41881 ttctatatga ttctataaaa aaagaagagg ctgggaaaac ccagcctctt cttttttatt
    41941 tctatgcttc tgctactgca ggagcttttc tcaataaacc ataaatcaca ccagatacga
    42001 ctgctccgat agcaataaac accaaataca tgaccgggtg actcagtaag aatacaacga
    42061 aaatcccgcc gtgaggagcc agtaatttga ttccgaaagc tccgactaat ccgccagtta
    42121 aagcagaacc aataataaaa cttggaatgg cacgaatcgg gtcagctgct gcaaatggaa
    42181 tcgatccttc cgtgacaaac gatagtccca tcacgatgtt cgtcaaacca gcatcttgat
    42241 ctgttttgct gaatttattc ttaaacaaac gtgtagcaac gaaaattgcc aatggaggta
    42301 ccattcctcc agccataaca gaagccatca cgacacttcc gccagttgca acagtcgtag
    42361 ctaaagttgc tgtaccaaac acataagcgg ctttgttgat tggaccgcct aaatctgccg
    42421 ccatcattcc agctaataat gcaccaagta aagcagcatt cgaaccactc atacttgtca
    42481 agaaaccgtt caatgcatca ttgattgctt tcatagggac attgaccagc aacatcaaga
    42541 aaccagtaat cagtaagcca aacactggat aaaagaggat cgttttaatt ccatccaatg
    42601 attttggtaa gttcttgaat aatttacgta aaaatacgat gacataacca gctaagaatc
    42661 caccaatcag tgcacctaag aatcctgcac cgcctgtatt agctaatgca ccagcagcaa
    42721 atccaacgat caaaccaggg cggtcaccga tacttgaagc aataaatcct gctaataccg
    42781 gcagcatgaa accaaatgca gcttgtccga tttggttgaa ccagctagca gcttgattgt
    42841 aattccctag atttgataat tgatcatgtg gcacgccaat aaattggtcg atcatgaaag
    42901 aaagcgcaat agcgattcct ccaccaataa cgaaaggtaa catgtgtgat acgccgttca
    42961 tcaaatcttt gtaaattctt tgtccgatag taccatccgc atttccttct tctgaactgc
    43021 tttcttttcc atcaccatgg aatactggtg cagtaccact aagggctaga ttgatcaact
    43081 cttctggttt acggatacca tcactgacag gacgattgat cagttctttt ccgtcaaagc
    43141 gattcatctc tacttttttg tctgctgcaa cgattacacc ttctgcacgg gcgatgtctt
    43201 cagcagtcaa tcggtttttg attccttctg aaccgttcgt ttcgactttg atctccacac
    43261 ccatttcttt cgcttttttc ttcaaagcat cttctgccat gtaagtgtga gcgatccctg
    43321 ttggacaagc tgtaacggca acaacgaatt ttctttctgg atgagcagaa gcttctgcag
    43381 cttgtgtttc ttgttctgct ttttcttctg cttctttttg ctcttcagct gtttggaaca
    43441 agtcttggac ttcttctggt gtatttgctt cttttaattt tcctacgaaa tctgcatcaa
    43501 tcagcaatcg agatagtgct gctaatgctt gcaaatgtgt gtcgtttgcg ccttctggag
    43561 ctgcgatcat gaaaaacaga taagttggct gtccgtctaa ggcttcataa tctactcctt
    43621 tttggctttt tgcgaataaa actgttgctt ctttaactgc actgtttttc gcgtgaggca
    43681 tggcgattcc atcaccaaga cctgtagaag tttgtgcttc gcgggctaga attccttctt
    43741 tatatgtttc gatatcggaa atccggccgg catcaaacat tttttggacc atttcatcga
    43801 ttgcgccttt tttatcagtc gcttgcaaat ccatgatcat cgcttctttg accattaaat
    43861 ccttgatatt catgattatc ctccttgaaa ctaatcaatt tttgtgattt caacttctgg
    43921 cagcaactca tcaatcaatt cgcgagctgc caagtcatca gaaaaagctg ttgcgcttcc
    43981 gcaagcaact ccccatttaa aggcttcgat tggatctttc gtacggctgt aagccccaat
    44041 aaagccagca atcattgaat cccctgcacc tactgaattt ttcaatgggc gaactaatac
    44101 attcgtttta taagttcctt gttccgtgaa gagcaaagca ccgtctccag ccattgagat
    44161 cagcacattc tgtgcccctt cagctagtaa ttttttccca tacggaatga tttcttctac
    44221 agattggaag gttgtgttgt aaagctcagc taattcgtga ttgtttggtt tgatcaacaa
    44281 cggtttctta acaagtgcat tttttaggtc atcacctgtt gtatcaatca cgaaatctgc
    44341 acctttttct cgaatgatat caatcagttc ttgataaaat ccttttcgca ggctagctgg
    44401 cgcgcttcct gacaatacga cgatatctcc ttgtcctact gttcctaatg cttgcttcaa
    44461 ctcatcgatt tcttcatctg aaatagatgg gcctaagcca ttgatctcag tttcagtgtc
    44521 tgattttagt ttgatattga ttcttgtatc ttcttttacg gttgtgaaca aagactggat
    44581 ttgttctttt tcaagccact tcgaaataaa ttcgccagtg aaccctccta aaaaccctag
    44641 tgctgtagat tgagaatcga tccgtttcaa aatacgggaa acattgatcc cttttcctcc
    44701 aggtaacttg aagtcttcct tcattcggtt caaatcgcct agttttaacc catctacgcg
    44761 tacgatataa tcaattgatg gattaagtgt tactgtgtaa atcattgtat tgcctcctta
    44821 attgttgtct tttcacggaa ttcattaacg aattctaatg gacaacgctc ggttatgatc
    44881 gtggctgctt ccaaaggtgc aacagaggtg aaggacaact ggttgaattt ggtatgatca
    44941 atcaatacaa atgtctcttc ggaatttttc atggctaaac gtttaacagc tgcctcttct
    45001 ggatccggag tcgtgaatcc ttgttcaaga tgggcaccgt tcattcccat aaatgcttta
    45061 ttaaaatgaa aattttttag ttgttctatc gcattagatc ctaaaacagc attagttgcc
    45121 agctttatcg ttccacctaa aataatggta gcaagctcca aatcaactaa atttgccgca
    45181 tgttgaacgg aatttgtcac tactgtgatc tgttttcctt gcagaaaagg aatcatttct
    45241 aacgtagtag agccagcgtc taaataaatg acatcttcgt cattaatggt ttcagctgcc
    45301 gatttggcga tttgctgttt ttcgtgaacg tttttgagtg atttttcact catattctgc
    45361 tcaaaattca ataattgctc tttcttagct ccgccatgaa ctctttctag aaacccacta
    45421 ttctccagct cttgtaaatc acgtcttatc gttgattcag aagcattcaa aaggtttaca
    45481 agatcttgtg atttcacgat tttctgctgt tcaagcaagt ctaggatttt ttgtctgcgt
    45541 tcctctgtaa gcattttcac gatcacctca atacaaataa tagcatattt tttttctact
    45601 agcaatataa atcagtcaaa aacgttcata aaaattataa atcagtcaaa aaaaaataaa
    45661 aaaccagtca gaaagactgg ttttttattt ttttgtctat catcaagccg ttttatcgtt
    45721 ttttattttc gcttcttgtt tttttcatat aaacagaagc aggttttctt tccttatgaa
    45781 gaagataata ataaagtccc atcccgccaa acatgaccaa aaaaccgatg actgatcgaa
    45841 taggaaaatt aggaacaaaa aagagacaga cggataataa tgatgccgga accattattc
    45901 gataatagag ttgtttatcc attttcttca cctcatattt tttgtaaagt aatcaattgt
    45961 tctaattctc ggtaatctaa aaattgcaca cgcagatgct gctcaccttt cttgacatcg
    46021 aattggatac ttcgccgctt tttctttatt cgtttgaagg taacatcaga gagtctatgt
    46081 ttgatttcct ttaacggtaa ttctgacagg gattctgaag gaacatagat tcttaaggat
    46141 aaaagatact cttgatattt ttcatctgtt acctctactt ctagatattc cctaatataa
    46201 taacaataag cttcgattcc attatccaaa gcaacagtcg gatcgataac tttatagcac
    46261 atcatgcgtg atcgattctc gtcaacccaa ggaaaatacg cctgagcatt tagtgttccg
    46321 cgaacacgcc tttctttata atctccttgt tggatatcat aactttttgt tacaaaaaat
    46381 gaagcattct ttttaggaac aggttgcatt tgtgcattct gatactggac agattggatc
    46441 gtatggtcag tgtaaatgta ttcaacgaat ggcggtttca ataaaccgac accattgtcc
    46501 caagcaagat gatcaaaccc aagctggtcc ctaaaatagg attgaaacat ttgattgttt
    46561 ggcttttgcc agttaaaggg gtctcgataa agctggatac atatgacttc gttttctaat
    46621 tccttcactt tttctacttg ttggatgtcg agaaaaatcg gtttagggat gatttgatga
    46681 taatagcgac tataatacat ttcccaacac gaagtgaaac ataaaccttg gtaaaaaaga
    46741 tcgtatcctg gaaattggtt gcaatcgact actacttccc cgttttgttg tttcatttta
    46801 ggtaaatgtt cgatttcatc ctttttctca aacaatagcc gttgagagat ctgttttgta
    46861 ttgtgataga taaactcgct ataagctcgc atataggcga acaccccatg agcaatcatt
    46921 tttttctgaa tgaagtctcg aatcaaaaat tgcttttctt tgaaaacaga gatagacaat
    46981 acatttttta tcaataattg attatcttcc aagcgaaaac tacattcgtt ctcgtcattt
    47041 cctacaacta accaactttc gtctcttacc gatgctagca ttattttttc ttgaagcttt
    47101 cgaagatcat acggatccgc ttgttgtgtg aaagagcgga taaatgttgg ctggatcaac
    47161 agacgtgtca aaatagccca atcgcttatt tcctgttttt tttcttcttc atttaagtct
    47221 gtgagctgga tagtcatcaa taatttatct tcgccaatca ttttctcacc tctttcaaat
    47281 ctttttataa tttaattata accaatgata aagaaaaact aaaactttat gtcttagaaa
    47341 ccaatttgga cgattacatg atagactaag taaaaagaaa caaagaggtg tttacaatgg
    47401 ggttgaaatt tgaacgtaca gataatttag ataaactttt cgaatcattt gctgtcgatc
    47461 cggaaaaaac agttgcacca aaagaagaga tcgatcgatt tctaaaacca cagccacaaa
    47521 atgaaaagaa aaaagacaag aaacaaaagt aagttaagct caaaaaaaga cttaccagcc
    47581 aaacttttat gaaagagttt gactggtaag tcttttttat tctttttatg attcaattgc
    47641 ttgttcgatt gctgcccacg cttcttcttt tccctgtttt gtaacggaag aaaagagaat
    47701 aaacgtgtca ttgcgatcaa aatccaacgc ttttttgatt tcgctctcat gcttgttcca
    47761 tttaccacga gggatcttat ctgccttagt ggcaacaaca attacaggga tatcataata
    47821 cttcaaaaat tgatacatct ggatatcttc ttgagaaggc ttatgacgca aatctactaa
    47881 agaaacgacc gcacgtagct ggtctctagt cgttaaatat gtctcgatca tctttcccca
    47941 ttttgctcgc tcagttttgg atacttttgc atacccatat cccggaacat cgacaaaatg
    48001 taatgcgttc tcgatcaaat aaaaattcaa tgtctgggtc tttcctggct taccggaagt
    48061 acgggctaaa ttctttcgat caatcaatgt gttgataaaa gaagatttcc ctacatttga
    48121 tcgtcctgcc agagctattt ctggcaattg tgtatctgga tattgttttg gtgccactgc
    48181 acttatgata atttcagctt gatggacttt catggtctct ctccttaaca aggtgatgaa
    48241 taaagcaagc ggctgtcgca aaagccaaaa tgacttttac ggcagcctct tttcatcaac
    48301 ccgctttttt ctctgaatct ttatagatta ctgttggctc accagacaat tcagctgctt
    48361 cttttgtgat aatcactttt tcgatgtttt catttgaagg gatatcaaac atcacatcca
    48421 tcatgatttc ttcaatgatg gaacgaagtc ctcgagcacc ggtattgcgt tcgattgctt
    48481 ttttcgcaat ggctctcaac gcttcaggtt cgaattcaag ttcggtatta tctagagaaa
    48541 gaagtttttg atattgtttg actagcgcat ttttcggctc agtcaagatc cgtaccagat
    48601 catctgttgt caatttctct aaagctgcca taacaggtaa tcgtccgata aactcaggga
    48661 tcaatccgaa ttttagtaaa tcttcaggaa tgatatgctg catgacactt tcgtcttcag
    48721 aaagtttttg gttttgtgta ccaaatccaa tcgtcttttc gcccatacga ttcttcacaa
    48781 tcgtttcgat gccatcaaat gcaccaccta cgatgaacaa tatgttcgtc gtatcaatct
    48841 gaataaattc ttgatgtgga tgtttacgtc cgccctgagg tggcacactt gcaacagttc
    48901 cttctagaat tttcagcaag gcttgttgga caccttcgcc ggaaacgtca cgagtaatag
    48961 atacattttc gcttttacgc gcaattttat cgatctcatc aatatagatg atcccttttt
    49021 ctgcaagttc cacattgtaa tcagcagatt gaagcaattt aagcaaaatg ttttctacat
    49081 cttcccccac ataaccagct tctgtcaaac ttgtcgcatc tgcgattgca aaaggtacat
    49141 tcaatgtttt tgctaatgtt tgtgctaaaa atgttttacc agaccctgta ggtccgatca
    49201 agcagatatt gcttttttgc agttcaacat catctgtgtt ttcttgtgct tgctgattga
    49261 cacgtttata gtgattgtat acggcaacag ctaacgagcg ttttgcgcga tcttgtccaa
    49321 tcacgtagtt attcaatact tcaagaattt ctagtggttt agggacttca gtgaattcgc
    49381 gtacagcttc ttcataaaat tcttcatcaa tgatttcttt acataggtcg atacattcat
    49441 tacagatgta gacccctgga ccagctacga tctttttcac ttcttcttgg gttttcccgc
    49501 aaaaagaaca gcgtacggtc tcattgctac ttggattgtc atacatggtc ttcacccctt
    49561 aacttgcaaa aagtatgcaa gaaactatca aagactttac agtcttttac tatcataaca
    49621 tagtttagta aaaagaaaaa gtgtttaaca aaggatcaac tgacctatac ctttgcattt
    49681 tttactctta acaaaaaata aggaactgtg acaaaatcgt gtcacagtcc cttatttcga
    49741 ataaacaatt ttctagaagt agcttcttca gaaatgattt attacttgat ttctattctt
    49801 tcgcttctgt cgctgtacct gtgatcaatt cgattgcttt tttcattgtc acatcatgtt
    49861 ccagcatatc ttctgtcaac acgcgtttga tttgttcgat tggcatgttg tatgtttctg
    49921 ataattcttg gatttctgca ttgatttctt cttctgttgc ttgaagattt tcagcagctg
    49981 caattgcttc gatcacaaga tttgttcttg tgcgcatttc tgcttcacct tcgaattgtt
    50041 tatgcaagtc ttcttctgta gaaccagtta attgatagta catttcagga gagatacctt
    50101 gacgttgcat gttgttcaag aattcgtcca ttgaacgatg tacttcatca tgaaccatca
    50161 cgtgtggcaa ttcaacgatt tctgcgtttt caacagccat acggatcgct gcttcatctt
    50221 ttgcatcgtc cgctgctttt tcttttgttt ctactaattc tttgcgatat ttttctttca
    50281 attcgtctaa tgttgatact tcgtcatcaa catcttttgc gaattcgtca tctaattcag
    50341 gcacttcttt tgcttttact tcatggattg tcactttgaa gactgcttct tttccagcaa
    50401 gatcttctgc ttgataatct tctgggaaag ttacatttac atctagactt tcacctgatt
    50461 tatgaccaac taattgatct tcaaaacctg gaatgaatga gcctgaacct aattcaagtg
    50521 agtaattttc gccttttccg ccatcaaacg cttcgccatc tacaaagcct tcgaagtcga
    50581 ttactactgt atcgccattt tcagctgcag catcttcttt gataactaat tcagcttgtg
    50641 cttcttgttc acgtttgata cgtgcatcca cgtcagcatc tgttacttca cggtcttgtt
    50701 tttcaacaac tagatcttta tattgtccta attttacttc tggtttcact gttacttcag
    50761 cagtgattac ccagtcttga cctttttcca tgctttcaac atcgattttt ggttgagaaa
    50821 caggatcgat gccagcttct ttgacagcag cttcataagc ttctggtaat acagcattca
    50881 atgcatcttc atataaagct tcttcaccgt acatacggtt gaatacttga cgagaaactt
    50941 tccctttacg gaatccaggt acgttcaagc tttttttcac tttattaaac gcagttgtta
    51001 atcctttttg gatttcgtct tgcgcaatcg taaattttaa aacaccatca ttcgtgcctt
    51061 ttttttcaaa tgttgcagtc atttaattcc ctccgagttt agaaattcat tttatacatc
    51121 aaaaacgttt catgcatacc tttaaatagt acactaaccc tttcaaattg taaacatatt
    51181 gaatggatag aatccttgtt tttcataaca tttttatctt tttcactgat aaaatctaat
    51241 ggaagaagat catttgctgc aaaatttttt ctcttttttt taaaaaatct tgtttttcat
    51301 cttctgtacc ttcatacatc gtttttcctg tacacgcctc tacagtcagt tgaaaccagc
    51361 gcttcgggtc ttcgatgtat gtatcataga caggataaac aattgcagat tgcaacgtga
    51421 attcttcttt taacacggaa ctaagcagcg catcttcatt cccgtaacga tctgaaaata
    51481 cacataattg ctggtaactt gcctgctgct gcggctttgg cagatctttt ggtatgactt
    51541 tgactaactt ttcttcaatc gtcaaataga aaacaggatg gcattcgttc aattgcctaa
    51601 gtgtctccag taattttgcc cttgctaaaa tatggacctc tggcgataca ataagtttac
    51661 tcgctgtttg gataaactca tgataaggaa gctgttcgat ctcatcaata gacgcaagct
    51721 gacgtgcagg ttccaacgaa ggaagttcct ccgatttatt gtggagtgcc ttgatcttct
    51781 gcctctccat ttgtccggat aattcttctg caaattggat tttttcaatg acccgctgct
    51841 cgaaagcttc ataaaaatct gtacttgcta tcaattttct agcatataaa aaatcttgtg
    51901 tactgattaa caagtcaaaa taaaattcag caaactcctc attttgaaga tactgttttt
    51961 catgcaagag tgcttgcttc aatgcttctt ttttctcgtc caactcgtaa agacaaaaaa
    52021 caagcaggct attagcctca aagctttctt tcaactcgta agctcgttga aataattctt
    52081 ttgcctgctg atattgctgg tttgctagtg cttgttgtgc cactcgcatt aaattctcat
    52141 atttttctgg aaaatcaatc ggcttcacgc agtgtcctcc tcttgctcat attcagctca
    52201 tgttcaatag tagcaaaaca aaaaaagcat gacaattaaa aataactgaa gcaccctcta
    52261 aaagctagat tttagatctg acttttagaa ggtgctttca actgttactg ctttttattg
    52321 ctcatcagct gttgacttcc tggttgaacg ctttgatcag attgatcgta acaacacttg
    52381 tattagtgaa aaaatcgccc agatgttgct ttttctgatt aaagactgct ggaagatacc
    52441 ctaacatcag caaaggaaat tttagaatga accggcaagc accttctcta actaaaacgg
    52501 ttgaccagct aagttcttct tcatcaaagc tgatgactcg aataccaaag atcattttcc
    52561 caatcgtttg gccatgattg aatttcgtca ataaaataaa atacgctaga taaataagta
    52621 aggctgtgaa tccgtagaga ctcagataag aatctgaaaa attaagccaa cctagatttt
    52681 tggcaatacc aagtgttaaa cgcgtaatag ctccgataca caaaagatcg accaagaagg
    52741 caaacattcg gataaaaaaa cctgcataga aatacttagg aaaatcattt gcttttggcg
    52801 gttcatttct tgtgtccgta tactttttcc atttacgttg tttctttttg atttcttcgg
    52861 gcgtcaaagg ctctctttca aaagagctca gtaccttttg ggaaaagttg gagtcaggtc
    52921 ctacagcagg ctgctgttgc ttatcttttt cttgttcctt attttcattt gaaagctctg
    52981 acatgcttac tcacctccgt aataatacat tgcttttggt gattccgctg tccctagatt
    53041 ctcaagaacg gataagatct gactagtctc agaaggcttc aatccctgga attctgctag
    53101 tttacttcct aaccatgtac tagcaaaccc agatggcgtg gaagaatatt ctactagttc
    53161 cgcatcttca agctgttgtt cctttcgtat agcttttaaa gcatcttcag gaaatcccaa
    53221 ttcatcgact aaacctactt cttttgcttg gacaccatca taaatccttc catcagcaat
    53281 ttttttgact tcttcttcag atttattccg tccctcgctg acgattgcta caaaacgact
    53341 atatgcgctg tcgatatatg cttgaagcac cgcttcttct tcttttgtct ctggtcgcgt
    53401 tcctgaaccc atatctttca acgctccgct tttaactgtt gtatcttcca cacccagttt
    53461 ttctagaagt cctgaataat tcaatcctga catgatcaca ccaattgagc cggtcactgt
    53521 ttcttctgtt gcaaagattt tatctgcttg agcagaaata tagtagccac cgctagctgc
    53581 catgtttttc atgctgacat acattgggat atcatgttct ttacgaatcg tatccaattt
    53641 cttagcgatt tccgcacttt cgtagacacc gccaccagga gaatttactt ctaaaaagat
    53701 acctttgact gttggatctt cttcaatcgc cttcagttgt tccataaaat ttttatgatt
    53761 gtaaccttca gaagcaaata aacctgaaga ccctcccgca gcaatcgttc catctactga
    53821 taattttacg attttttgcg tactgtctcc ctcttccaac acatttggag ctagttcttc
    53881 atccccatat aaccaactgt tcaatccctc aatttgatcg ttttcctgag gcttagtcaa
    53941 actagctgaa actaacgaaa ccacaaataa tcctgcagca atcagaactg ctgcccaacg
    54001 tcttttattc attctttctc ctttctaata caagtttttt atgacgatca cagtttctga
    54061 ctgctcagaa gtgtcgaacc gctctgcttt ttcttcccgc gcatacccgg aaaacgactc
    54121 ttttgttaat tcatcttcta ccgtaaactc acgagcttga gcaacttcca aggcatcagg
    54181 tgcgatttct tggatgctat cccagccagt atctaaaaat attttcgtat catctgatac
    54241 accagctgat gcttcgaatt tggacaattg tttttttaac attcccagtg tcatgatctc
    54301 aatttttgaa tccattttta ctcctcctct atccgattac tttctattgt accgaactcc
    54361 tgaaaaagat gatagataaa aacccattat tttttgacat aaaaaggaca tttgacaaag
    54421 aatttgatat ataccaattt attttttatt ctttttttgt tgacaagaac attcgcaaaa
    54481 ggttatgatt ttaaatgttt ccagataaaa aacaaaaagg aggatagtta taccttttag
    54541 gatagcgcca ggtctgtgta aacagatgac gaggagaggg tttatcgaaa gattcggcgg
    54601 atggccctag ggactgcact ctacagaaaa tccacaaaaa atgtctgcaa agataaaaca
    54661 aaaggatttt cctgcagctg gaagcattca tacgaattca ttatagaaag taggatgttt
    54721 tttatgtgcg gaattgttgg aatgattgga ttaaaaaatg taacaccagg attgattgac
    54781 ggtctagaaa aattagaata ccgtggttat gattcagctg gtatctttgt ctcagatggc
    54841 acaactgatt atctggtcaa agcacaaggc agaattcaaa atttgaaaaa caaaataaat
    54901 attgatacta caggaaatat aggtattggt catacacgat gggcaactca cgggcaacct
    54961 tctgaagaaa acgcccatcc acatacttcc caaagtggac gcttcgtgct cgttcacaac
    55021 ggcgtaatcg aaaactttga agaacttaaa attgcttatt tagcaaatga ccactttatt
    55081 ggtgagaccg atactgagat tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca
    55141 acgcaagagg cgtttttaaa agctttgcgg gtcatcaaag gttcttacgc tttcgctttg
    55201 attgatcgga cagcacctga tgttatttac gtcgctaaaa ataaaagtcc actattaatc
    55261 ggactcggcg atggattcaa tgtgattgcc agcgatgcaa tggctatgct tgctcatacg
    55321 aaggaattcg ttgagattga agatgaagag atggttaccg tcacatcaga aaaagttatt
    55381 attcaaaatt ttgcaggtga catcgtagaa cgttcttcat tcgaagcaca agtagatgct
    55441 tcagatatcg agaaaggtac ctatcctttt tatatgctga aagaaatcga cgaacagcct
    55501 attatcatgc gtcgtatcgc tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat
    55561 caaaagctgg tcgatacatt gtctgatagc gatcgaatct atatcgttgc ttgcggaact
    55621 agttaccatg cggggttagc aggtaaacag actttggaaa aattgacaca gattcctgtt
    55681 gaggttcatt tagccagtga atttggctat aacacacctc ttctttcaaa aaaaccattc
    55741 tttattttct tgagtcaaag tggcgaaaca gcagacagcc gccaagtgct ggtaaaaatc
    55801 aaccgtctcg gctacccttc acttacgatt acaaatgttg ctggttctac tctttcgcgg
    55861 gaagcatcct ttacactgct attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa
    55921 gcttatactg cacaaatagc tgtactaact ttattagcca aagctatcgg tgataaaaaa
    55981 gaatttgaaa cttctcttgt attcgatatc actcatgaat tgagtttagt tgctaatgcg
    56041 atggaatcgg tcatcgccca aaaagattat ttagaagagt tggcagaagt atatctcagc
    56101 gatacaagaa atgcctttta cattggacgt ggtgctgact acaacgtttc tcttgaagct
    56161 gctttgaaat tgaaagaaat cagttatatc caggcagaag gttttgccgc tggcgaattg
    56221 aaacatggaa cgattgcttt gatcgaagaa ggaacaccag tgatcggaat catcagtgaa
    56281 gaagtgactg gtgcgcatac tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa
    56341 acactagtta ttgtctcaga gggattagaa aaggaaagtg accagctggt gctaccaact
    56401 gtccaccctt atctaactac tctaaccaca gtcgtaccga ctcaattact tgcatattac
    56461 gcaacgctat tacggggatt cgacgttgac aaaccacgta atttagcgaa atcagtgaca
    56521 gtagaata
//
LOCUS       DASHWW010000011        52527 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.011, whole genome shotgun sequence.
ACCESSION   DASHWW010000011 DASHWW010000000
VERSION     DASHWW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.011"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..705)
                     /locus_tag="U2R64_000808"
     CDS             complement(<1..705)
                     /locus_tag="U2R64_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEM8917648.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
     gene            1393..1551
                     /locus_tag="U2R64_000809"
     CDS             1393..1551
                     /locus_tag="U2R64_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8917649.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1623..2849
                     /locus_tag="U2R64_000810"
     CDS             1623..2849
                     /locus_tag="U2R64_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8917650.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="U2R64_000811"
     CDS             complement(2938..3330)
                     /gene="rpsI"
                     /locus_tag="U2R64_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEM8917651.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="U2R64_000812"
     CDS             complement(3346..3789)
                     /gene="rplM"
                     /locus_tag="U2R64_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEM8917652.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4308..4775)
                     /locus_tag="U2R64_000813"
     CDS             complement(4308..4775)
                     /locus_tag="U2R64_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEM8917653.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4895..6433)
                     /locus_tag="U2R64_000814"
     CDS             complement(4895..6433)
                     /locus_tag="U2R64_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HEM8917654.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6513..7199
                     /locus_tag="U2R64_000815"
     CDS             6513..7199
                     /locus_tag="U2R64_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEM8917655.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="U2R64_000816"
     CDS             complement(7400..7927)
                     /gene="msrA"
                     /locus_tag="U2R64_000816"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEM8917656.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="U2R64_000817"
     CDS             complement(8011..8688)
                     /gene="pgmB"
                     /locus_tag="U2R64_000817"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEM8917657.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8685..9815)
                     /locus_tag="U2R64_000818"
     CDS             complement(8685..9815)
                     /locus_tag="U2R64_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEM8917658.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9815..11998)
                     /locus_tag="U2R64_000819"
     CDS             complement(9815..11998)
                     /locus_tag="U2R64_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEM8917659.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11995..13020)
                     /locus_tag="U2R64_000820"
     CDS             complement(11995..13020)
                     /locus_tag="U2R64_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8917660.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13065..13892)
                     /locus_tag="U2R64_000821"
     CDS             complement(13065..13892)
                     /locus_tag="U2R64_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEM8917661.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13889..14956)
                     /locus_tag="U2R64_000822"
     CDS             complement(13889..14956)
                     /locus_tag="U2R64_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HEM8917662.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14982..15818)
                     /locus_tag="U2R64_000823"
     CDS             complement(14982..15818)
                     /locus_tag="U2R64_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8917663.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDFFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15815..16684)
                     /locus_tag="U2R64_000824"
     CDS             complement(15815..16684)
                     /locus_tag="U2R64_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8917664.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16754..18037)
                     /locus_tag="U2R64_000825"
     CDS             complement(16754..18037)
                     /locus_tag="U2R64_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEM8917665.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18051..19736)
                     /locus_tag="U2R64_000826"
     CDS             complement(18051..19736)
                     /locus_tag="U2R64_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HEM8917666.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20011..21036
                     /locus_tag="U2R64_000827"
     CDS             20011..21036
                     /locus_tag="U2R64_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8917667.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="U2R64_000828"
     CDS             complement(21631..25305)
                     /gene="rpoC"
                     /locus_tag="U2R64_000828"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEM8917668.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="U2R64_000829"
     CDS             complement(25363..28980)
                     /gene="rpoB"
                     /locus_tag="U2R64_000829"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEM8917669.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29708..30676
                     /locus_tag="U2R64_000830"
     CDS             29708..30676
                     /locus_tag="U2R64_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8917670.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30694..31599
                     /locus_tag="U2R64_000831"
     CDS             30694..31599
                     /locus_tag="U2R64_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917671.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31596..32402
                     /locus_tag="U2R64_000832"
     CDS             31596..32402
                     /locus_tag="U2R64_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8917672.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32538..33527
                     /locus_tag="U2R64_000833"
     CDS             32538..33527
                     /locus_tag="U2R64_000833"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HEM8917673.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33844..34368)
                     /locus_tag="U2R64_000834"
     CDS             complement(33844..34368)
                     /locus_tag="U2R64_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HEM8917674.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34655..36436
                     /gene="scm"
                     /locus_tag="U2R64_000835"
     CDS             34655..36436
                     /gene="scm"
                     /locus_tag="U2R64_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEM8917675.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTSSTTSDSSDSST
                     SSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSN
                     NWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(36591..37577)
                     /locus_tag="U2R64_000836"
     CDS             complement(36591..37577)
                     /locus_tag="U2R64_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEM8917676.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(37600..38166)
                     /locus_tag="U2R64_000837"
     CDS             complement(37600..38166)
                     /locus_tag="U2R64_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HEM8917677.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(38180..38596)
                     /locus_tag="U2R64_000838"
     CDS             complement(38180..38596)
                     /locus_tag="U2R64_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEM8917678.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(39053..40987)
                     /locus_tag="U2R64_000839"
     CDS             complement(39053..40987)
                     /locus_tag="U2R64_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8917679.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            41268..42224
                     /locus_tag="U2R64_000840"
     CDS             41268..42224
                     /locus_tag="U2R64_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HEM8917680.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            42314..43417
                     /locus_tag="U2R64_000841"
     CDS             42314..43417
                     /locus_tag="U2R64_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEM8917681.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            43430..44383
                     /gene="menA"
                     /locus_tag="U2R64_000842"
     CDS             43430..44383
                     /gene="menA"
                     /locus_tag="U2R64_000842"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HEM8917682.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(45318..46664)
                     /gene="gor"
                     /locus_tag="U2R64_000843"
     CDS             complement(45318..46664)
                     /gene="gor"
                     /locus_tag="U2R64_000843"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEM8917683.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(46798..48051)
                     /locus_tag="U2R64_000844"
     CDS             complement(46798..48051)
                     /locus_tag="U2R64_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEM8917684.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGEHRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(48057..48980)
                     /locus_tag="U2R64_000845"
     CDS             complement(48057..48980)
                     /locus_tag="U2R64_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEM8917685.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(49201..51693)
                     /locus_tag="U2R64_000846"
     CDS             complement(49201..51693)
                     /locus_tag="U2R64_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEM8917686.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(51700..52167)
                     /locus_tag="U2R64_000847"
     CDS             complement(51700..52167)
                     /locus_tag="U2R64_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEM8917687.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(52304..52377)
                     /locus_tag="U2R64_000848"
     tRNA            complement(52304..52377)
                     /locus_tag="U2R64_000848"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52341..52343),aa:Arg,seq:acg)
     gene            complement(52435..52508)
                     /locus_tag="U2R64_000849"
     tRNA            complement(52435..52508)
                     /locus_tag="U2R64_000849"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52472..52474),aa:Pro,seq:tgg)
BASE COUNT        15247 a        11070 c         9606 g        16604 t
ORIGIN      
        1 aataaatata gtatctccat aggctttttt taaattctct tcattaaata cagattctac
       61 acttccgtga gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac
      121 cttgcttaaa tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa
      181 cgtatccata attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa
      241 tatgaaatcc gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc
      301 agataattct cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt
      361 tgaaactctt tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt
      421 tcccatagat acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg
      481 ctctacatat gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc
      541 tccctgatga gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt
      601 tggaccaata atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc
      661 taaaaaatcg ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta
      721 aatgataatg attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa
      781 ttttataatt tagatttttt tctgttgctg aagattagaa tgacaaaact atttgaaact
      841 acgcgtatag taagtagctt tcaaaatata taaaaaagga gcgttctcaa atgagaacat
      901 gctcctaaaa ctactttatt ggcgtatgga aaaattatac ttaaagtgga tagcgggttg
      961 aataagttga taagcatcaa aacatttata aaaattattc aagactatgt ctgttccata
     1021 tacaaatatg aaaatcagta aactccattt aacttttttc gtagtgtgtc tttttataca
     1081 tgtttatcgt tattaatagt gaataggaaa aaacctattt ttgatcattg acaattaaat
     1141 acaatttttg aataacgatc cctgctattc gagctagaaa ctcaagtacg ccatgacctg
     1201 attagcgaca aatacttaga gatttctttt tgttctggga aaacaaaatg ccatgacaat
     1261 agcagcaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
     1321 atgtgcttac ccaaagcaat tcaaaaattc taatcttttt taggagatga ttttataaaa
     1381 ttgagagtct acttgaataa aaaacaaacc tgtgagtttc taggaattga taataatact
     1441 ttagataagt ggattcgtat atataatttt ccagtaatca gaattgacgg tatagttcgc
     1501 tttgacatag aggatatcaa agattttatg aatacattta aaacaatttg aaaatttctt
     1561 ctcgccgcat atactaagaa tagcgaaata tactgcctta ctttttaagg gagtgaggaa
     1621 ttttgcctac aaaactttca aatgggaaat ataaaactaa tctgaggtat ccaaaaaaat
     1681 tcagagaaat cactggaatt acatcagaaa agtatcaaaa agtatttcca actaggcaat
     1741 tggctattaa agccgaaaat gcaatgaaaa ggaaaattga aacagtttta agagaggaga
     1801 atgcaaattc actagaatta aaaggaaaaa taaaatttaa ggaattctat gaatcaaaat
     1861 ggcttcctag atatgaacta ggtcagacta ctagatcaaa aagagctcca agttacgtaa
     1921 caattagtaa tactaaagat atattccgat tgcacatcct tccaatgttt ggtgagtatg
     1981 caatgaacta tctaaattca aatactgaga taatatcaga tgaattaaca aaaaaatcga
     2041 aagaatacgc aaatataaaa attatcaaag gatatgtccg ttctatgttt gatattgcag
     2101 aaatactaaa ttatattgaa tttaaccgaa ctaccaaaat tattcaatgt atcactgcac
     2161 ctaaaaaaat tgctttagaa gaaagaagga tacgggaagg taatcaagca ttatcgtcag
     2221 aagagcttat tgcttggata gaagcagtaa acactgactt gaataatcac ttgcttactc
     2281 ttcatgacta tactcttttc atgcttaccc tatatcttgg tgatagaaaa agtgagacgt
     2341 atgctttgca atggaaatat atcgactttg agaaacaaac ggttcgcctt aaacatgctt
     2401 tggataaata tcaaaaaaag aaatttacaa aaggtcgaaa ggataccgta attcaagtac
     2461 ccgaaattgt aatggcatta ctaagcaaat ggaaatcagt gcaagctgag caattgttga
     2521 gattaaaaat taatcaaaca ccagatcagt atctctttac ctatactaaa ccatccggag
     2581 aagtaaattg ccctgttcac gctgattacc taaactatcg aatcaattca attaaaagac
     2641 gacatcctga attggctcat ttatctccac ataagcttcg tcatacctat gcaactatag
     2701 ctagacaagg cggagcaaat atgaatcaaa tatctagtgc tttaacacac tcagatattt
     2761 ctacaacgag aatatacgta aatacaccag atgtagtaga taaaactgtt tttgaagcct
     2821 ttcagagagg attgaataaa tgtgattagt atgtgttctt aaatgtgttc ttaaacaaga
     2881 aaaagacact tttcaaacaa ttgaaaagtg ccttgaaaca ttgatatata aataatatta
     2941 acgtttagag aattgagatg ctttacgagc ctttttgaga cctggttttt tacgttcgac
     3001 catacgtgcg tcacgagtaa gtaagccagc acgtttaaga gctaaacgga agtcaggatc
     3061 aacttctagc aatgcacgag cgataccatg acggatagct cctgattgtc cagcgtatcc
     3121 tccgccgttt acgttaacaa atacgtcata tgcgcctttt gtttcagtaa cagcgaaagg
     3181 ttgattgatt acttcacgca agtcagcatg tggaatgtat tcttcaacat cttttttatt
     3241 tacagtaatt ttgccagttc ctggtactag acgtacgcga gcaactgcgt ttttacgacg
     3301 gcctgtgccg atatattgaa cttgtgccaa tgaaattccc tcctattaga ttaagtttgt
     3361 gatgtctaaa acttctggtt gttgtgctgc atgtggatgt tctgctccac cgtatacgtt
     3421 caattttgta aattgtttgc ggcctaaagt gtttttagga agcatacctt ttacagaagt
     3481 ttcgatcaaa cgacgagaat ttttagcacg caattcgcca gcagtgattg atttcaatcc
     3541 tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc gcttttttac ctgttaattt
     3601 cactttgtct gcattgatga cgatgacgaa atcaccagta tccaaatgag gtgtgaaagt
     3661 tggtttattt ttaccacgta gtacagatgc aacaactgtt gaaagacgtc ccaatggaac
     3721 atcagttgcg tctactacat accatttacg ttctacttcg cctggtttgg ccatatatgt
     3781 tgtacgcacg ttattttcct ccaatttaag ttctgatgtt tgacatacac ttcgagtttc
     3841 cggggctctt tgtggggcaa acaataccat ttaacatatt acccgctaat ctagtcaatg
     3901 tcaacgtttt tctgcttgat tgaaaaattt atatgaaact ttacttcttt tctttctttt
     3961 atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa gaggctgtga caaaagtctt
     4021 gtcacaaccc cttattttga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca
     4081 caatatccat aaaacataag aagctgtttt ttaaaattgt ttcttgtgac tcggagctga
     4141 acggcaggct tacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
     4201 caaaaaacgg caaaatatga ggaactattt tgacgtttgt ttctctaata ctcaggtcaa
     4261 aacgctgatt tcacaacctc tttttcggtc aagttcaaca acagttttta cgcgtcgatc
     4321 tctggcgctt tgcccaaatg agcttggatc atccagatac gtttttctgt ggctgttttg
     4381 aattcgataa agatatcttg tgttggatcg tcgccttctt ctccagaaac ttcgattcct
     4441 ttttggtaaa gatctgctag ataacgatag cctgcaacaa gtgtttccaa acgttctgga
     4501 atagtacgat cccagcggcc aatttcatca gggatttttg tgttatctgc aaattcacgc
     4561 aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt cggatacttc atctaactga
     4621 gcgttcaaat catccatgaa ctcatccatc attgggtgca atgtaaggaa acctggtcct
     4681 ctcatgtacc aatgtgtttg gtgaacaaca acagacattt ggcttagatc tgcaactaat
     4741 tgatttaata cttctttggt ttgttggaat ttcatctttc ttgcctccta acattttctt
     4801 acacttaaaa taatagtaga ctttcaatga aaagtacaac aaaatcattt acctgagaac
     4861 gattttcagt tcgctttttt atccgtaaag ccaatcattt ttcagaatca gctaattctt
     4921 ctcgcagttg agcaaattgc tgataagtct gtgctaaatg cttttgtgtc gaaacaaata
     4981 atggatagat tttctgatat tttttatgat cagtttcttg tactccaact tgctctttca
     5041 attctatcaa ttcctgtgct tcactgatac tttggatctt tccgatgctt ctccagccta
     5101 aaatcacagc tcctaatgcg gatgcttctg tgacagtagg gaaaacaagc gggtaaccca
     5161 gtacatcagc catcatctga cgaaaaatcg gagattgagc aaacccgcct gtagcacgga
     5221 tctctgtgag ctgattttcc tggcaaactc cttttaaaat ccgataaagg ttgagacaga
     5281 tcccttctag aatcgccttc atcatttctt tttctgtatg ttgccgctgt aaaccgataa
     5341 aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc accaagtaaa tagggatgaa
     5401 aaatcagacc attggcaccc gctggcacaa aagcgatagc cgaaagcagt gcatcatatg
     5461 gattttctcc tttttcttta gcagattgaa cgacttcctg taaaaatgta tgccctgccc
     5521 aatcaaagat gccagcacca ttgctagtcg ctcctcccac tacccaatgt ttctgatcca
     5581 gaacataaca aaacgtctcc atttctggat ggaactgagg ctgagtagta ataaaacgaa
     5641 gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc accaaaagca cctaacccta
     5701 gattagaaag cggcccgtct gcccctccca aaacaaatga tatatcattt ggcaaaccta
     5761 gttctgctgc tgtttttgat ggtagacctg ttacttgata ggtggaagga aagacttgcg
     5821 gcaattgctc tattcgaatg ttcaagtagt caagcacttc ttctgcccat tggaattcat
     5881 ggatatcaaa atatccagtt cctgaagctg ttccgtagtc gctgatcagt tcgccaaaca
     5941 atctataaaa gatatagtct ttgataccga caaaataagc agtttttttg aataattcag
     6001 gttggctgtt ttgcagccac ttgattttgt tcaatggtgt cattggatga atcggcgtcc
     6061 cagtctgccg ataaaattct ttgccaagca cggtatattt cagtttttct gcttcgtccg
     6121 ctgctcggtt atctgcccaa gtgatcattc gagataacgg tgttttctct tcatccaaca
     6181 atatcaggcc atgcatcgca gaggagaagg agacaaattg aatgattgtg tctgaaggca
     6241 actgtttaat tacttctttt ataacggtgc agacaccttg aaagatcaat tcctgatctt
     6301 gttctgccat cccttgtgtt tcttggatca aagggtagcg aaaataagcg gatgctgctt
     6361 cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt ggttccgata tctaatccga
     6421 ttgaaacgtt cattttttca cctcaaattt tatgtatgta caaaaattta gtttaagctt
     6481 gcgtatcttg gttttgaaaa gggggagatg gcgtgttact ttattttatc attggttgct
     6541 gtatcggatc atttttatgt ttaaccgccc agcggattcc gttaggtcac tctattattt
     6601 atcctagatc tcattgtgtc aaatgctgtc gttcgctttc ttggtatgaa ttgattccga
     6661 ttctctcgat catcgtccaa cgatttcgct gccgctattg caggtgtcgg ttgcccttct
     6721 actatttgtt ggcagaagcc ttatgtggtg gtctttttgc ctggttcttt actttttctt
     6781 ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc tttgctattt tcgttgatgg
     6841 atttatttta cttcatggtc cattctcaca cgctattctg ttcttgggca attttatgga
     6901 ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt gctgttaacg tttatcgtag
     6961 gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc tggcgatact ctgttgatgc
     7021 tttcttggag tggtggcttg tctctagaag agttgcttca gatcttgttt cttgctagtc
     7081 tgtttggaat atccgttttt tctgtttact ttatctgtca taaaaaaaag ttggaaaagc
     7141 tgcctttcat tccttttttg agcagtgcgt tgctgattgt ccttcatctt aggtattgaa
     7201 aaaaggttgt gacaaacgac ttgtcacaac ctctgatata tagtgttctc ttaccaaatc
     7261 cttgtgactt ggagctaggc gacaggttca caacctctcc actaaatggt gttcaatcag
     7321 ctgaccctca gtattagctc aaaatgctgg ttttacaacc tctgatatac ggtgttccat
     7381 aagtagcttt ttcggcttct tatttcttga cgccccaatg tcgacgaagg aaacctgcac
     7441 gtccagaacc ttctcgataa agattgtaat ggagcttgtt tttcttgtaa taatcctgat
     7501 ggtaatcttc tgcaggataa aattcgcttc ttggttcgat ttttgtcacg attggcttat
     7561 cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc tgcaatattt cgttcttctt
     7621 catcattata gtagatcact ggacgataag aatcaccgcg atcagcgaac tgtcctaatg
     7681 cgtcagtcgg atcggtttgc tgccaataga tttccaccaa ctgatcataa gaaataactt
     7741 ctggatcata ttcgatctct actgcttctg tatgccctgt tgtgcctgtt gttacttgtt
     7801 cataagttgg atttggtaca tgcccgccag tataaccgga tgtcacagaa atgatccctg
     7861 gctgctcttc aaatggtttg accatacacc aaaagcatcc gcctgcgaaa actgcttttt
     7921 ttgtcatata aaatccccct tttttctcat cataccttga tttccaaaag gaggataacg
     7981 ttttgcttgt gacagaaaaa acggaaacta ttatatacgt gatacggctt ctgataaatg
     8041 ccaaaacgaa cgtacttgat caaaaacggt taaatcagga atcacatatt cagcagaagg
     8101 aagatttatg ttttcaccta ttcccaatac atgcatgtta ccagccaaag ctgcttgaca
     8161 accagcttct gaatcttcaa tgaccaagca tgcatttggc ggtacattca attgctgtgc
     8221 tcctttgaga aaaacttctg gatcaggttt tgcttttgat acttgcgtgc cgtcaataag
     8281 gacatcaaaa taacttgtca aattcgtttt ttctaaaatg aggcgtgcat ttttgcttgc
     8341 tgatcccaat ccgatcttga tgtttgtttt tttcaagtac tcaagaacag ctattgcacc
     8401 aggcaaaacg gatgtttcat ccattttttg aatcgcttga agatatagat tgtttttttg
     8461 ctcagcaaag gctgatttct ctttttctga gaatttctgt tccatttttc caaatgacag
     8521 caatcgctct agtgactcgg ttctggatat tcctttcagt tgctcgtttt ctttctcagt
     8581 gaatggaatg gacagctggt tagctaaaac cagccacgct tcgtaatgat aacgagctgt
     8641 gtctacaaga acgccatcta aatcgaatag tgctgctttg attttcatcg attacctcct
     8701 tgaaaatgaa cgacttgaag taaagatgcg atgtttttag ctgtgcgatg aagattatca
     8761 gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag gaaggatcgg aaaaacggcc
     8821 gaaatgccaa catctgctgc tttttcgctt cctttaccaa cacttccgca aatagctatc
     8881 acaggaacgc cctctggtac tcttctagca atcccaactg gcgcttttcc ttttagactt
     8941 tgtccatcta gacgtccttc gcctacgatt acgaggtctg cttgctgtac ccgtttatcg
     9001 aactccagta aatccaatac gtagtcgatg ccagagacta ttttccctga agcaaatgct
     9061 aacagtcctg cacccattcc accaccagca ctactgcccg atgcctcgat tacttgaggg
     9121 gcaaatctca tataaaaatc atgcatggct tggtcagcca ctgctaattc attttctttc
     9181 aagccttttt gtggtccgaa aacaaaagaa gcgccttctt ttccgcataa aagattagta
     9241 acatcagtaa tgacagtgat tttggcttta atcagctcaa taggcacgtt cgttttatca
     9301 actgtagcaa ttttacctag attttctccc agtgcttcta ctttttgatt atcttgatcg
     9361 taaaaagcat aacctagacc ttctgccatg ccgatgccgc catcgttggt actacttccg
     9421 ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca attgtcgtat cagttctcct
     9481 actcctcgcg tggataacct aagtggctgt tgttggttta gtgggacatc tttcaatccg
     9541 acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg aagcgtactg gatttctttg
     9601 tttttgccaa atgcattagt aacgactgct gtttgccgct tcaaccttaa actgtctgct
     9661 aatgatgaaa ccgttccttc tcctccatcg cctataggta gcagatcata ttcagcctga
     9721 acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg cctctaaggc tgtcagactt
     9781 tctttgaaag aatctggcgc aatcagaata cgcattattt tcccctccgt tccaagatca
     9841 gttctttttc cagctggtat tggtctccat tgacaaaaat aggtaatgtt tctttcgtct
     9901 ctttttttat tactatttgt ttttttgtca aaacaaatag caacctgtga tttttccaaa
     9961 taaaaggaaa agaaattttt tcccatgctg aaggaagtct tggagaaata gaaagagttc
    10021 cattcgttac tgtaatacct gaaaaaccaa atataactgc tagccatagt gctcctaatg
    10081 aagcagcatg aattccgtca tctgatgaat gcggatctgg tcctaaatca atcaggcacg
    10141 cttcttggaa taaatgatac gcccattcca tttcttggat acggcaagcc tctatggcgt
    10201 gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt ttcatagtaa tgcaaattct
    10261 tagaaacgat tggttgagaa aaatactcag gtaataagta taacagcatg acaagatctg
    10321 cttgcttgct gacttggagt tcatttactt cgctacgggc ataatcaagt aaaatagact
    10381 ggctgccagg acgttctttg taagtggtca aatcaataac tggcttactg agatacgtgt
    10441 catcttgcgg aatcagctgt tctttgttag gcactggcaa atataactta tctaaaaaat
    10501 tttgacattc tttcaaaaaa agcggatcgc cagcttgata tttaacagct aaggccacat
    10561 tataatgcgc cagatagttc gtatatgcat tattgtcgat atattctgtg tattcatctg
    10621 gaccaatgac tctgtgtatc tctaaatgat catcgacttt tacagctctg ctcagccaaa
    10681 aagctgctgt ttcatgaatg agcgtttttc cctttgtttc taaaaacgat tgatcctctg
    10741 ttgcttggac atactcttga acggcataag caaggtctgc actgatatga tgttctgcgg
    10801 cagctgaagc aacttcttgt cttgttccgg ttttgatatt caatgcagca aatttgggtg
    10861 tctcttcctg accagtgtgt gcgctttccc atgggaaaag tgcaccttga tagtgataat
    10921 ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg gtacagcagc aaattctttg
    10981 ctacttcagg aaactgatat aaaaagaaag gcaggataaa aatttccgta tcccagaaaa
    11041 catgcccttt ataaccttcg ccagttagtc ccttcgcccc tacactaaca cttggatcat
    11101 tgcggggagt cataatctgt aaatggtaag cagcgaagtc catcgctaac tgatcgaaag
    11161 aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa atctgtccaa taagacatcg
    11221 actgctctaa aatttctgta taactaacgc ttttctgggc ttgggcaata cttttcttaa
    11281 acgggtctgt ttgctgaaga gaggtagaga gcacgatgat cttctccagc gtaaaggacg
    11341 tattttttct gatcttttct gaaaaggaag cggtgatccg gcgatttttt gcttggaata
    11401 cacctgcttt attgaattta gctgcaatcc caatatcaat tttactttct gttgtctggt
    11461 aggatgcact gatcaaatcg tcaccaaata ctcgcagttc tttttcaacc aactgctgtg
    11521 taccaaaatt ggtttgctgt ccatcgatac ccgttttcac atctacttgg cagtcttcgg
    11581 tcaacggctt gatgaccact ttcagggctg cctgatggag attattttga tcagcaacac
    11641 gacaagtaat gacttccact ttttttcctt gagcagtttc aatgagcgca tagcgtttaa
    11701 gctctcccat ttctaaatct agtgcccgct cgtatgcaag aactttcatc gtctcaagag
    11761 aaaaatgttc accgtcgatt tttatttccc atctgatgac atctgggaga ttcactaact
    11821 cggctgattc tgctcctaaa ggtcggttat atacaccagc tgcaaacatt ccccttactt
    11881 gattccgata gtcttcctcc tggcttcctc tgataccaaa aaatccattt ccaatggtca
    11941 tctgactcgc atacttattg atatactcta aatcaaactg tttttcttct actttcataa
    12001 ggtaataact tctcctgttt ctgccgaacg atataaattt tccaccagat tctggatgac
    12061 atatccttgc cagccatctg caatcatctg agtctggtca ccgagcgccc gattcacaaa
    12121 atgagccata cttagttcat gtgggtcatt aactggcgtg gtcttttgta aggaaaccag
    12181 ctttccatct acatcttcga atagttcgcc tggatacaga ttagcacctg cctgatcgcc
    12241 acaaaaagcc acattcagtt tgtcttctct gatattcaaa gcaaacgaag tattcagttg
    12301 gatgatcttg ccgttttcta attccagtgt gccaaaaatt gcatcttcta ctgtgaattt
    12361 gcttggatcc catttcccga atttccctga attttttttc gtaccaattt tttggaagct
    12421 gtacgcccga acgcttttta ctttaggaaa tccagtaata tacatcgctg tatcaagcat
    12481 gtgaatgcca taatcgatca aaggcccgcc tccttgaagt tctttgtcga taaacgttcc
    12541 ccagcctgga acaccagacc gacgaagcgc attcgcttct acgtaataaa tatccccgag
    12601 aacatcaaga tgattcttga tcattgttgc ttcgtcagaa aaacgatgct ggaatccata
    12661 agccaaaatc tgcccgtttt tatcggctgt ctctgccatc tttcttgctt gatcagctgt
    12721 catagctggt ggtttctcgc acatcactga agcattagct tcgagggcag ccaatacatg
    12781 ttcgaagtga aagcgattgg gtgtacagac actcacgata tcgggagaaa tctcattcag
    12841 catttgtgta actgatgtat acgcatgaga aaatcctgta cgtcggcaaa agtcttctgc
    12901 tcgctggctg actggatcaa ccacagcggc caattctaag acatctgatc ttttttgata
    12961 ataagcagca tgtacttttt ctgctacttg tccagcgcct atgattgcta ctttcttcat
    13021 ttatttctct ctcctttgct tatttactta ttgttattct ttctctattc tttctctaaa
    13081 tcatttaaat gacgcgctgt ttccagacag tttttcaagt attgcaatga ttcctgataa
    13141 attttcactt cattttctcc tcgcaaacga cattcatata ccatataacc ttcatactca
    13201 ttttgaagta gcgtttgaaa atggcgagta aaatcaattg cgccagatcc tggttggtag
    13261 cgatgattat ctgctaaatg gatatgaccc acatactctt tttgcgtagt caatgctttt
    13321 gaaatatcat cttcttcaat attcatatga taaaaatcag cgatgatctg cacatgtttc
    13381 aattgattag agtcaatgta atgacgcgca tccgctaaca aattgatcat atggtcttgg
    13441 tatcggttca aaggctccaa ataaataacc gtacctgttt cttcggctac tttatctaaa
    13501 taacgaagtg attcgctgac tgctttatag tctccttctt tgcttcgggg tgaaaccatc
    13561 ggcggtaatc gataagtgaa cattccccaa gctgctggga taacgattcc tttgcctcca
    13621 acctcgctta gtgcacgcaa aatctcagca atttgacgta caccattaag acgccgttct
    13681 tcgataaagt caccgatcca cccatcgtag ccgttacaag ctgtcactac tgggatccct
    13741 gtttctttga ttgcctgttt gactgtgtcg atattttcta ttaacaactt accgtcgatt
    13801 tcgtattctt caaatccaca gtctttgata aatctaaatt tttctaaaat gtctcttggg
    13861 aaaaatgctt gatcttgcgt accgaatttc attgttctcc tcctcggact tgaacgccca
    13921 ttttgatact ttcttctggg tgctggtcta cataacgcat gtaagcttct gcgctttctg
    13981 caaatggcac aactggatca atgatttctt cacaatccaa gtaaccgttc atcaataatt
    14041 cccaacatgt gtcctcgatt cgtttacggt tccatcttgg gtaatctggg tttggttcac
    14101 tagatgctcg agcaaagacg atttttgcat tattgaaatg tgcttcgcga ccaagattaa
    14161 acccagctgg aaaaggttta gcaaaggcaa cataagaaat gatcccgcca tagccgatcc
    14221 ctcttaaaga agcttgtaat gcggcagcac tgccactcgt ttcaataact gaatctactc
    14281 cacgtttatc tgtcaattcc tttagacgaa aaccgacatc tgctttcata ggatctagcg
    14341 tgtaatcggc accgtatttt tctgctaatt ctctacgctg cgctatggga tcgatcccaa
    14401 cgatggtagt agcacctgct tttttagcta attgaatcgc aatttgcccg atagcgccta
    14461 aaccgaagat tgctacagca tcacctgctc gaacatgtgc ttcccggata ccacctaaag
    14521 cgaattgagc aggatcgtaa catactgcat ttttccattg atccaaccga tcaagtttac
    14581 gtagtttata attatcaaca ccgtttgtaa tcagcgtttc acgaatgggt ccataagtgc
    14641 agactaactc tcctttttga tactctgtca ccaaactgcc cgtttcttcg atcgtaccga
    14701 caatcatatt tcctaattga aattcgccaa ataccacacc gcgttggctt ccttcttctc
    14761 ttggcaagaa taggcgccat tcttctgaaa attcttcatc gataaatgga cttaatcctc
    14821 taaagtcgac aatttctgtt cctggttttg gagtagcgaa aattactcgg atacgtactt
    14881 cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc ggctattctt ggttctaatg
    14941 caactaattt tttcatcttt tctttcctct ttcttttctt tttatccttt tacgccgcct
    15001 tcgactaaat cacctttaat aaatcgttca gataacgcat acataatgat gactggtaaa
    15061 gcggtcacca atgaagcggc catcattcgt ccccaaatgt agtctggtgt actgaataat
    15121 gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg acaggaaaat cgaagcaaat
    15181 aaataatcat tccacgaaac cataaagcaa taaacgaaga cagaaatgat tccagaaata
    15241 gccaatggta taatgatccg aataatgatc tggatccggc taagaccatc gatcattgct
    15301 gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt ttagcatgaa tatcgcagta
    15361 ggaagtgttt gaacgaccat cgtgataatc agtgctgtat tggtatcata caaacctaga
    15421 ccggaaatga ttttaaataa tggaacaacg atcaaaatac cggaaaacat ataaacggtg
    15481 taaaagctag cattgatttt cgagcgagct ttgaagcgta gttttgacaa agcgtatgcc
    15541 ccgctgatcc caatcactac tgcagttacg gaggctatca aggagatcac taaactattt
    15601 ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa aatcctgata atgttcaaaa
    15661 gtccattctt tcggaaaaat agtttgtgtc gttgcaattg cttcttgtga atccttgaat
    15721 gatgtcatca gcatgatcaa aaatggaaac aaattgacag ctaatagcaa caaaatcgtc
    15781 gcgtaaaata agattttcct gctcttttta tttttcattt caagtccacc ttctttcgtg
    15841 agagcaagac gaccgctgca ataatgatga acaatagaat cgatatagct gctgcttttc
    15901 caagatcatt gaacgcaaag gctgtctgat acaaataaac gcctaagata ttgactttat
    15961 tcgtcagtag atagacatct gtaaacatat agaacatcca gatagatcgt aaaacaatca
    16021 cagttgctag tactggtttg attgccggca gtgtcacgat cttgaacttc tgccaagcat
    16081 ttgcaccgtc catttcagct gcttcataaa gcgttttgtc gactgtttgc aaaatagcca
    16141 aaaatgaaat aaacgcatac ggatagtatc tccagatagc aaacaaaacg accataaaga
    16201 agctagcaac tggctggtcg aaccacagcg gtgcttcgtt gaaaagctgc aacctatcta
    16261 ctaacagatc attgacgatt ccataactat tattgaacat atatttccaa gcaaaaatca
    16321 aagaaataga tggcgtaaca taacttaata aaatcagtga acgcaccgtt ttcctaaatc
    16381 tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa agctgtactg cctgctacaa
    16441 ctaagaatgt gtaagcaact gttaaaccta aagaacgata aaattcacta tcacttaaaa
    16501 tttcaagata attgcttaat ccgataaaaa cggcgtctga gttaggattc agcggcatat
    16561 cgaaaaaact gatctgaata ttggaaagca ttggaatcag cactaaaaca gctaataaaa
    16621 gcatgcttgg tgctaaaagt cccatggcta attttaagtc agaatgtttc cttggacgat
    16681 tcattgaaac ctccccctga taatctgcca atagctatct acttttttcg aacaccattg
    16741 gcagaacttc ttgttatttc gtattttttt gtgcgtcagc taaagcttga tcgacatctt
    16801 cgtttccgac agttacttgg ttcactgctt ttccgatcac acctgagctt gtgatatctc
    16861 ccattttcgt gaaattcttt tccccgacta gtccaaagac ttgtacttca tcaaaagcac
    16921 tagcaatctc agatggcagc tcgccaaaag acttgatgac ttcattttct ttgtaaccat
    16981 ccagttcgac tacttgttta ttcactggtt gagcaccacc aggagacatc aagacccact
    17041 tttccatgtt tttcggttga gataagaaag ctgtgaatgc ttcagcagcc tctttttgtt
    17101 tctcgtctag accagaagaa atcgtcaatc cagatactgt gccatagaca gcttgatctt
    17161 tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc cgcttcataa acagaaggca
    17221 aaatgtaagt tgaatagatt gccattggtg ctgttccatt catgaaagca tctttgattt
    17281 ctgtcacatc attagagcct ggcatcgtgt attgggataa gttttgataa aacgacaatg
    17341 cttctctcat cttttccgta tcgatcgtta cctcgccttc atcatccaaa acatttgctc
    17401 catttgacaa agcaaattga gagaacgctt gctcactcat tgttccttca gcagtaggca
    17461 tagcaattcc atattgttta ttctctttat ctgtgaaatg ttgagcaatt tttaaaatat
    17521 catcccaatt ttctggttct gaaaaaccag cttctgataa tttttctttg tcataccaaa
    17581 taccttgaac ccagccgcta attggtgcag caatatagct ttttccatct tctgaacgaa
    17641 caaggttttt ggctccgtca taataattat cttctccagc ttcctcgata acgttttgga
    17701 ctgccgtctg atcaatcagt tcatctttat ccatcacttt agcaaaatcc tgactgactt
    17761 ccattacttc tggtaattta ccggaacgag ctaacgtaac gatttttgta ttgaacgctg
    17821 attcttctac cggcacttgc ttgattttga tgtctggatt ttctttttca aaatcagcaa
    17881 ccagttcatt gatcacactt aatcgttcct gttcgacaga agagtgcatg aattgaatcg
    17941 ttgtctgttg tgattcgtta gagctttgac tttcaccaca agcagtaaga agaaatccag
    18001 tagctagcag acaggtagta acaataattt ttttcatttt tttccacctc ttattttatt
    18061 attttcagcc acatatattc atacggctgg aatatcaact ttcgttcttg actgcaatgg
    18121 ataatttgtc cagaaaacag gtctaggtaa tctccttttg gtaaaagata acctgctgat
    18181 tgattggaaa aattatggat aactaagact ttctcttcct tcgcttcgcg aataaaactg
    18241 ataaaagaat ctgctgagtc cagtaagtaa atcaaactat tcggatggaa ggctttttct
    18301 ttttttcgaa tagatagcat ctgggtcaat tcaccatata ctgctgttct taatggatct
    18361 gtctgcaact ctttctcaat atctgctaac aaaaattttt gccgattgat ttttcgattc
    18421 tctcctgttt tttctacgcc tttgtaatca tttcgacttc ccagcacact ttgaatataa
    18481 attgccggca cgcctggtaa cgttaccaaa aatgaatgag cagctaaaaa gcgtttgctt
    18541 ctccattccg tcgtatctgt tggagaactt aacgcatcta gatacgtagc gtttatctca
    18601 tatggactgg tcgttccatc tgggtttttc ttgtagttta ctcgggcacc ctctttcttc
    18661 agctgttcca ctaattcaag gatcgttttt tccggcagaa tacctcgtac cggattcaat
    18721 ccgataccgt catgggaggc taaaaaatta aaaaaagttg tttttttcga tgcgaaatcg
    18781 atggttttta accattcttt caacttactt gtattacccg aacgaatcgc ttgaagggtc
    18841 aaaggtggta gcgaaaactg atagaccatc tgtgcttcat tctcgccatt cccaaaataa
    18901 ctgatattat ctttgtgtgg cacatttgtc tcagtgatca ataccgttcc tggagctgct
    18961 tcatcagcga ttgcacggaa taattggatg attttatgcg tttctggcag gtgtatacaa
    19021 gaagttccta gttctttcca taaaaatccc acagcgtcca agcgaataaa tgaagcgcct
    19081 ttttctaagt aaaacaaaag aatatcgatc attttcaata aaacttctgg atttttaaaa
    19141 ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt gtttttcttt cccgtttttg
    19201 tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag tcacgctgct tgtatctgta
    19261 tccagtggca aatcaataaa aaaatctttg tacgtatcat tcaagtttaa atattcctga
    19321 aaccaagtac tttcggcaga catatgattg cagacaaagt cgaacattaa ccgtgtttcg
    19381 cttctcattt cttctatatc ttcccatgtg cccaaacggt cgttgattgc ctgataattt
    19441 acaacggaga aaccatcatc agatgtatat gggaaaaatg gcaagaaatg tacaactcta
    19501 aatgtatctg ccaaatactt ttgataaaat ttcttaaatg tacgcaaagt tggttgctgc
    19561 tcttcaaaaa attgatcccc ataagtaatc aagaaaatat cttcttcgtc ccaatgcagt
    19621 ttgcctgcct ggcctttctt ctgctgataa acactgactt tttgttcaat catagaggcg
    19681 gttttctcag acaaatctga gtcgcgataa atcgcttgta aaagttttgt atacatcgga
    19741 ttcccctttc ttttttggga gcgttcccaa cgatttgatc atattatgga aaacgcttac
    19801 tgtcaatagc atttttttaa atatttttga tatacacaaa aatacaaata agaaagctta
    19861 tgtatcaata attaatagct tcttaaaaaa atatggtctc tcatgatcat gcaagctatt
    19921 cctaaatttt caaaatcata gacaaaaaag aatgtctatt gtactatgga attattctaa
    19981 aacgctccca aaaaggaggt gcatataaaa ttgaaaccta ctatttatga cattgcgaaa
    20041 aaagctaatg tctcaaaatc aactgtctcc agagtattaa ataaccagcc aaatatctct
    20101 gataaagcaa aagcaagtgt acttcaagca atcaaagaat tgaattatga accgagcaaa
    20161 attgcaagag gactgtcagg aaatggtttt gacgcgattc tagcattatc tcatcgtact
    20221 tctcatacga cctatggcaa tccttttttt tcagatgtta ttcaatccat ttctgccgtt
    20281 tctgaacaaa ataacttcga cttgattcta caaacggcaa aaacaccaga agaagagcta
    20341 gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag gaattattat tttaagctct
    20401 acgatggatg aaacacttct ttttgaattg gatcaataca atattcctat tgtggtaatc
    20461 ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg acacggataa tttccaggat
    20521 agttacgatt tggtggaaac actgatcaag aatggacacc gtcatatcgg ctgtctccat
    20581 gctccgacag aagtttatgt atccaatgat cgtctcaatg gttaccgtca atgcttattt
    20641 gatcaccacc tagatatccg taatgaatgg attatagacg gcggctttcg cttagaagat
    20701 agcatggcag caatgaatga tttaatgaag ctacgagaaa gaccaactgc gattttttct
    20761 accgatgcat taaaatcatt gagtatttac aaagtggcag aacaatctgg aaagcagata
    20821 cctgatgatc tttcgatcgc aggattcagt gatcccttat tgtcctccct attttcgcca
    20881 cagttgactc ggatagacat tccgacaaat cagttaggaa tcaaagccac agaactttta
    20941 ttccaactaa tccaccacca ataccctgaa gaaaaaagaa tcattctttc aaccgagatt
    21001 actctcacag attcgatcca acaacaagaa atgtagaaca gaattataaa agaacagaaa
    21061 cactgaggat aagtcagtta ctctgttctt ttttcaatca ctcatccctc gttaccccct
    21121 cccggtattt tagcgaattt ttcttatttt ccatctgttt tagatagctg tggataacta
    21181 taatgtttgt gttaaactat tttttccaca gggaagaaaa aactattttt aaccacgttg
    21241 tgtataagtt tttatagttc gtttttttaa acacatttac ccttatttca atccatgtta
    21301 tttggggata cttatctcta aaacataaat agaataacag acatgtctac tggttttgtt
    21361 ttattcgagg aattattcaa taatagctag caaaatatta aaaataaccg ctctatcttc
    21421 ccatcaattt attttgcatt caaaaaatga tctatcttta cttttgttga ttgacttctc
    21481 ttggaagatg atcgttccga taccttaatt ggatacgaac cgatgttgtt aagatccttt
    21541 cccacttttc ttctagttag acaaattatt ttagacaaac caaaaaagag gttgtgacaa
    21601 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
    21661 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
    21721 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
    21781 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
    21841 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
    21901 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
    21961 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
    22021 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
    22081 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
    22141 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
    22201 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
    22261 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
    22321 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
    22381 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
    22441 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
    22501 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
    22561 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
    22621 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
    22681 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
    22741 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
    22801 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
    22861 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
    22921 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
    22981 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
    23041 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
    23101 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
    23161 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
    23221 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
    23281 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
    23341 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt tgaatcgttt
    23401 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
    23461 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
    23521 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
    23581 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
    23641 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
    23701 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
    23761 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
    23821 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
    23881 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
    23941 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
    24001 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
    24061 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
    24121 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
    24181 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
    24241 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
    24301 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
    24361 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
    24421 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
    24481 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
    24541 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
    24601 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
    24661 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
    24721 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
    24781 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
    24841 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
    24901 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
    24961 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
    25021 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
    25081 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
    25141 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
    25201 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
    25261 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
    25321 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
    25381 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
    25441 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
    25501 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
    25561 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
    25621 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
    25681 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
    25741 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
    25801 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
    25861 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
    25921 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
    25981 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
    26041 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
    26101 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
    26161 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
    26221 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
    26281 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
    26341 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
    26401 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
    26461 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
    26521 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
    26581 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
    26641 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
    26701 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
    26761 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
    26821 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
    26881 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac cgtcatgttt
    26941 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
    27001 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
    27061 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
    27121 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
    27181 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
    27241 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
    27301 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
    27361 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
    27421 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
    27481 acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca attcgccaag
    27541 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
    27601 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
    27661 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
    27721 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
    27781 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
    27841 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
    27901 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
    27961 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
    28021 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
    28081 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
    28141 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
    28201 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
    28261 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
    28321 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
    28381 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
    28441 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
    28501 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
    28561 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
    28621 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
    28681 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
    28741 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
    28801 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
    28861 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
    28921 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
    28981 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
    29041 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
    29101 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
    29161 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
    29221 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
    29281 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
    29341 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
    29401 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
    29461 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
    29521 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
    29581 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
    29641 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
    29701 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
    29761 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
    29821 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
    29881 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
    29941 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
    30001 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
    30061 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
    30121 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
    30181 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
    30241 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
    30301 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
    30361 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
    30421 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
    30481 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
    30541 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
    30601 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
    30661 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
    30721 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
    30781 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
    30841 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
    30901 gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
    30961 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
    31021 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
    31081 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
    31141 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
    31201 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
    31261 atttctaatg gatgcattgc tctttctggc tccttacttg cgcaaaacaa cggctttgct
    31321 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
    31381 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
    31441 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
    31501 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
    31561 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    31621 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    31681 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    31741 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    31801 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    31861 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    31921 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    31981 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    32041 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    32101 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    32161 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    32221 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    32281 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    32341 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    32401 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    32461 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    32521 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    32581 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    32641 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    32701 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    32761 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    32821 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    32881 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    32941 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    33001 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    33061 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    33121 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    33181 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    33241 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    33301 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    33361 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    33421 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    33481 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    33541 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    33601 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    33661 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    33721 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    33781 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    33841 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    33901 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    33961 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    34021 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    34081 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    34141 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    34201 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    34261 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    34321 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    34381 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    34441 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    34501 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    34561 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    34621 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    34681 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    34741 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    34801 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    34861 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    34921 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    34981 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    35041 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    35101 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    35161 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    35221 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    35281 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    35341 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    35401 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    35461 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    35521 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    35581 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    35641 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    35701 tgatagctca gattcatcaa cttcaagcga cagtacagat actacctcta ccacaagtga
    35761 tagcacggat acatcagctt caagcgacag tacagatact acctctacca caagtgatag
    35821 cacggacaca tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgacagcac
    35881 ggacacgtca gcttcaagcg acagtacaga tactacctct accacaagtg atagcacgga
    35941 cacatcagct tcaagtgaca gtacagatac tacctctacc acaagtgata gcacggacac
    36001 gtcagcttca agcgacagta cggatacatc taccacaaca agtgatagca cggacacgtc
    36061 agcttcaagt gacagtacag atactacctc taccacaagt gatagcacgg acacgtcagc
    36121 ttcaagtgac agtacagata catcctctac cacaagtgat agctcagatt catcaacttc
    36181 aagcgatagt acagacacgt cgtctaccac aagcgataca cgtcatgcaa gtgtctcctt
    36241 ctcaaaaaca agttcggata acaggacgaa ctttaactta actaataaaa caagcaatga
    36301 caatggaaac aaatcaaaaa gagcacttcc taaaactgga agtcaatcga ataattggat
    36361 aacactcgca ggcgttatat tacttgtaat cggtttaaga atcactttta tgagttataa
    36421 gaaatcgaaa aggtaaaaaa atattcaaga taaaaaagag caacgtcgct aacggacgtt
    36481 gctctttatt tttgcttttt atcataaata caagaactac aattcaattt gtcaaaaaac
    36541 acgtagattt ccttctgaga aatttattta cgtatcgaac ctttccctat tcagtctttg
    36601 cgatccaaaa tcagttgggt aagggaaaag agattctctt ttgttcgaag agaggtggca
    36661 ggtaatttct ttatttcctt caaagccttt tctgtgtaag aggccgctaa cttcctagct
    36721 tcttccacgc ctcctgtatg ttcaacgatt ttgcgtacgg cgtcgacatc ttcttctgtc
    36781 attgccgctt tcttctctaa ataaggtagt agctttggtt tgtttttttg caaagagtag
    36841 atcaacggta aagaatagac cccttgacgc atgtcttcta gtacaggttt gccgatttcc
    36901 tggctctctt ttgtataatc taaaatatca tcgataatct gaaaggccat cccgatagaa
    36961 agtccgatat ctcctgcttt ttttgcgaag cgctcgcttg ttccactttc aaaagcgcca
    37021 acagaacaac ttaattggaa cagttcagct gtcttacctg aaatattttc caaatattct
    37081 tttacagaaa gttcataatt atagcgatca tccatctgcc ctaattcgcc attcaatact
    37141 ttttccatac tgcgagaatt caattggaga cttttcaagg aagtggagta atcagacaat
    37201 agtttaaaac agcagacaaa taaatagtct cctgcataga cagaaacgac attaccaaac
    37261 tgactacgga tattaggctg accacgtcgc agatccgctt catcaacgat atcatcatgg
    37321 atcagtgtgg ccgtatggag catttcgata gaagctgcca aagcgatggc tttgtctcga
    37381 tcttgctctg gtccaaattg tgagaacaat agctgatagg caggacgcaa cagctttccg
    37441 ccggcatgga tcgtttcttt gatggcttgt tcgacaggtt tgtttttcag gcggacagtt
    37501 tcttccatcc gttttagtgt ttctgtcaat tctttactta aagcaggata gttttcccac
    37561 attggatgta gcttcataaa aaaactcctt gtgtgacgat tattttttgg taaacattgg
    37621 gctccatttt tgtttggttc cctgctcata atctttttgg aatcgttgaa gtgtctgcac
    37681 atgtcgtaaa agataattcg ctgcgatccc gattgcaatc cctgataaaa tccctaaaac
    37741 tgaaaggact ggcaagtaca acatgactgt ccatgattgt gcaatgaaag aagccatcaa
    37801 aagctgtccg acattatgca tgaaaccgcc ggccgcacta attccgatga tactgacacg
    37861 ttttggtcct aattgcttga ccaataacat tccaaaataa ctaagcaaag caccactcat
    37921 actataaagg aatgtggaaa tcgttccgcc tagcaaagta gtcaggaata gtcgtagcca
    37981 aagtagtaag aagctgtctt gttttttcat ggtaaaaatg gcaacgatcg tgattagatt
    38041 ggctaagcct agttttgcac caggcgcaaa agaaaaagga taagggatca tattttccaa
    38101 taaaccaatg atcactcctt gtgcaacaag tagcgaaata taaatcattt tttgtaattt
    38161 actcatggtg tgtgaaggtc taataaatca gactgtcttc gtcacctcca tctgttgaac
    38221 ggacttcgat cactaattta tgtggcaaac agacgatggt ttcgccattt ttcgttgccc
    38281 agcctcgacg tacgcagatc tggtcatcgc aatctgcttc ttttatccgt actcgatcgc
    38341 catctatctc gatcaagtta taatctccgt gttcatcttt gtaagtatat gtgttgctct
    38401 cttctccagc catcaaaggg aatgttttga tttctgtgcc atccacacgc agtaccgctt
    38461 ctttttctgc tgttgcggtg ttttgctgaa gaccaaaaat catgactggt aaaaaagaaa
    38521 gaacagtcaa aagcaaaata ataaaaacat cccaaggttt gagcagactt ttttcagcaa
    38581 attctttaag gctcattttt gttctccttt ttccagatta actcacccaa ttttagcata
    38641 aaaacaagag gttgtgacac ctgtgtcttg ctttgagtaa taagaacgaa gaatagaaaa
    38701 cagctttcca tgttttctaa ttctttgggc ttattaccga gaagcagcag gtggaacacc
    38761 gtttataaca agaggttgtg acagaagtgg gcaacttcaa gaaataagaa ggaatttacg
    38821 aaaattactt ttcaagtttt tgtgaaattt cggcttattt ttcgaagaag ctacttctgg
    38881 aacaccgttt ataacaagag gttgtaacag aggttgtgac acctgtgtct tgctcatgga
    38941 ggcttatctc gggcatctta ttcctttaat tttacataaa aaggaggctg tgacggtttg
    39001 tctcagcccc tttctattga aatcttgcat tcaaataacg ttctttatct atttatttct
    39061 tgccgtactg ggaacttggt ctaccgtacc accaattacc tagtgtacgt tgtagccatg
    39121 gaattaccca gcgatccaac ccaatcgcac gtccggaacc gttcatcaat gcgaaagcaa
    39181 caaaaatgaa ccaaatgttt acccagtaaa acatgcctga taagcagaac gtgatcacca
    39241 atacaatcgt tgtcgcactg catagccatg tgaataatcc agcaatcaat gctaatgcca
    39301 aggcaatttc aaagaatacc atgaattttt ggaagaacat tgctacatca ttgtttggca
    39361 tgatcacttg catgatcttt gtgaaccagt ctggtgactt ctcaatcaca gccattggtt
    39421 cttcaccgta tgcataactc aaaccaaaat gtgcagcttg agtcgctgct tctccggcac
    39481 ttgcccctgc tccgctggca gctgtggttg catcaccagc agcagaagca ccactggcaa
    39541 catctgttac attgtattcc catgtccaag ggaacacact gtttccagtg aaccatgatc
    39601 cttcaccaaa ccaagtactt ggtttgaaca cttcaccatt cccaatgatt tttttggaag
    39661 cttcaacgaa ccaaactaaa ccatagaaaa tacgaagtgg cacactccat aagacattgc
    39721 cgtaacgaga agaatgtcct cgagtcacgt tgcgatcatc tttgatatgg aaaaactcat
    39781 gcattaaata ttggaacata taataaccag aacgaatatc aaagaagtat ttcaaattca
    39841 cgatatgttt cattacgata gctaaaaatc cgcttaaatg gatcttatca aataggttag
    39901 ctacccccca tttggcacca atagaaacca taaatccttg atagtttcct ttaaatttat
    39961 gcttttctcc gcctttgatc gaagccacga tattcgctgc ggctgtgtgt cctgtttgtt
    40021 cagcagcttg aacgatctgc ggtgtcggtg ttcctgggaa ttcttcataa aagactaaat
    40081 caccaatgat atagatgttt ttatcttcgt agccttttgc ctgcatatat tcattggcga
    40141 tcaaccgctg tccgcgtgct gattctaatc caaagtcagc agcgtcagaa gttcctttga
    40201 caccagctgt ccaaatcagt gtgtgagtcg gaatgttgcg tccgtctttc aatttgatat
    40261 gatcagcagc cacttctacg attggtgcat tcaataataa ttccacgttg tgcttacgca
    40321 aatagcgttc agcttttgca gcatcatttc gatccaacat attcaagatc gtcggcattg
    40381 cctctacgac catcagtgtg atttcgtttg gatctaattt ataatctttg gctaggcgat
    40441 ttttccagtc gatcagttcc ccaatcattt caataccggt aaatccagaa ccacagacaa
    40501 cgaaagtcag catggcttta cgcagttcat catctggttc caatgcagct tttgctactg
    40561 tcttctcaat atgttcccga atccttacag aatcttcaaa tgaccaaagg gtgaatccgt
    40621 gtgctttgac accaggtgta ccaaagtcat tcggctctcc gcccattcca aggatcagct
    40681 gatcaaaagg ataggaacct aatttggtct tgacgatttt tcgttcttta tcgataccga
    40741 ttacagtgtc tgtgacaagt tgtacattct tttgacgagc aaacaaatgc tgcagatcgt
    40801 attggattgc ttctggttct acacgtccgc cagctacttc atgcaactcg gtcatcatag
    40861 tatggtacga atgacgatcg atcagagtaa ttgctacatc ttcttttttc agtttctttg
    40921 ccaagtattt tgtagctgaa acaccggcat atcctgctcc tacaacgaca atattttgct
    40981 ttgccattga tcatccgctc cttatagact atctatataa tgaatatatg ataattcttt
    41041 tagtttgata cttattacac aatctccata tattatatag atgttctgtt cttttgtcta
    41101 actccttttg gatttttttc aaattttaaa ataaagcgtt ttttcacgaa atttgctgaa
    41161 agaaaacgtt tgaaatatta catgggttat ttatcaaaaa tagttgactt ataggctaaa
    41221 aagattagaa tgtataatga atcacaaaga aaaattgtgg actagaaatg gaatggtggg
    41281 gtattaaaat gaagaaaaaa cgttttgtaa ctggatttgc cgtattagca ttttcagctc
    41341 tagtgttagg cgcttgcggc gcagatgaca acggaagctc aaactcttct tctgaatcat
    41401 ctacagcaca atcttcgact gcaaaaagca caacagaatc atctgcaaaa gttgtagctg
    41461 gcggagattt gcaagacggc acatataaat tagaagaaaa aaattattca aatggttacc
    41521 gtgcagtctt tgaaatggtt gtaaaagacg gcaaaatcac tgaatcaaaa tatgataacg
    41581 tcaatgaaaa cggcgaatca aaaacaaaag atgcagaata caacaaaaac atggaagcaa
    41641 aatctggcac aaacccagaa aaatacattc ctgagttgaa tgaccaattc ttaaaagcac
    41701 aaagcgcaag cggtgtggaa gtcgtaactg gagctactca ctcatctgaa agcttccaaa
    41761 actacgcaca acaattgatc caagctgctc aagctggtaa cacagataca atcgaaatcg
    41821 acaatggtgc tgatttgaaa gacggcactt acaagcttga agaaaagaac tactctaacg
    41881 gctaccgtgt gcaattcgaa atgacagttg ctggcggcaa agtaactgaa tcaaactttg
    41941 attatatcga caaagacggt aaatcaaaac aagatgatac agaatataat gaaaatatga
    42001 aagcaaaaag cggtacagaa ccaaaaactt acatccctac tctgaacgac gaattcgtca
    42061 aagcaatggg cgaagaagat ggctcacctg ctaatgtaga agttgttaca ggtgctacac
    42121 acagctcaca ttcattcatc atgtacgcac aacaattagt gaatgcagct gaaaaaggcg
    42181 acactcaaac aatcgaagta gataatatcg taacagaaaa ataatcacat aatcatacta
    42241 ataaaagttg gagggtggga cgatagccag attaggcagt cgtctcacct ttcaaaatga
    42301 agagaggaaa aagatgcgga aaaaactact attttcctta atcacactgg gcatctcttt
    42361 tatggtgcta actggctgca gcaactcagc aaataaaaca accactgaaa gttcagcagc
    42421 taccaagata ttgaaagatc catattctga tgaacagttc ttgttaggga cttacgttcg
    42481 tatccgtgtg tatgatgaag gcaaagaatc agcattgaaa cctgccttcg atcgagtaaa
    42541 agaacttggt gataaaatca cgatcaatca aaaaggttct gagatcgatg aagtgaatga
    42601 gcaagctggg atcaaaccag taaaagtttc tgatgacgtc tacacgttag tcaagcgggc
    42661 ctacgaatat agccaagatt ctcaaggcgg attcgatatg gcgattggtg caatcacaca
    42721 attatggcga atcggttttg atgacgccag aaaaccttcc caagaagaaa tcgatcaggc
    42781 attgaaatta gtggattatc ataagatcga actaaatgac aaagaaaaaa ctgtttatct
    42841 aaaagaaaaa ggaatgatca tcgatttagg tgcaatcgcc aaaggttaca ttacggacga
    42901 agtagtgaaa gtcttgaaaa aacaaggagt gaccactgcc atcgttgact tgggcggtaa
    42961 tgtctatgtc ttaggccaca gcccaagagg cgaaaaccaa gactggacag tcggcatcca
    43021 agatccgaac atggctcgcg gatctgtttt aggttctatt aaagaacgga acaaaacatt
    43081 agttacctct ggaatttacg agcgttattt agaagtagat ggcaaaaaat accatcattt
    43141 gtttgatcca aaaacgggtt atccgttcga caatgatatc gcaagtgtca cgatcataac
    43201 agataaatca attgatggtg acgggttgtc tacagcagtc ttttcaatgg gtgtgaaaaa
    43261 aggactggaa tacgtcgaaa gcgaattgaa taacgggacg gaagcgatct tcgtgacaaa
    43321 agacgataaa gtatatgtga ccgatccaat caaagacacc ttcaaattat cggaggactc
    43381 ccattacacg atgggtgacc gttctgaact aaaataagga gtacgaacca tgacactaaa
    43441 aatcttttta gaagtagttg aaatacgaac aaaggtggct agtgtatttc cttttgcggt
    43501 aggggtatta ttctctatcg ctttttttca tgagatacat tggctaaaca cttttttatt
    43561 ttttattgga atgctagttt ttgatttagc gactaccgct atcaataatt acatggatta
    43621 tgaaaaggct cattctgaag tatataagta tgaagaaaat gtcattggcc gcagaaatct
    43681 atctcctgta ttgattcgaa acatgatttt agctatgatt gcatttgttt ttgttatcgg
    43741 cgttattcta acgatcaata cgggttggct tttacttttg atgggattta tctgttgttt
    43801 tattggagta ttctatacat tcggaccgat tcctttatct cgaatgcctt taggggaaat
    43861 tttcagtggg gtgactatgg gccttggaat ttttgccatg gtcgtttatg tcaatacatt
    43921 cggttcagat gtctatgatc tgacagtcaa cttttcatct ggacaatttg atttggtagg
    43981 aaatctttgg gctatagcag caatcgtatt agcttcctta cccttggtgt ttacgattgc
    44041 caatatcatg ttggctaata atttgcggga tcttgaccgt gatattgaaa atcatcgcta
    44101 tacactagtt ttttatatcg gacgtcctgc gggaacagtc ttattccagc tattgatgta
    44161 tgcttgctat ttcgtgattt taatggggtt gttgagcggt atctatgaat ggccgatctt
    44221 ggtcaccttc ttgaccttgc caattgtgaa gaagcatttg gatcaattca agcaaacgtt
    44281 accccagcct atcagtttca gctattccat caaaaatatg gtcttattca atgccagtta
    44341 tgtattgggg ctattactaa caatcattat gcaagccatt taacagcatg aagaggttgt
    44401 gaaaaaactg ccctgcatca agtaataaga acagccaaat aaaaatagct ccttatattt
    44461 ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt atcaggaggt
    44521 tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
    44581 tttttgcata aatttggctt aataccgaga aactggcttt tgaacaccgt ttatcagagg
    44641 ttgtgaaaaa gtcgcttagt ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac
    44701 atttttgcat aaatttggct taataccgag aaactggctt ttgaacaccg tttatcagag
    44761 gttgtaaaat cagtgttttg tcctgagtat tagagaaaca aatggaaaaa tagttcctca
    44821 tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacacta tttgttcgga
    44881 aaaagtgact aactatgaca caattttttt cacagtccct tttttcactt gatttgattc
    44941 gtaccagcga acttgacgag aactttcttg gtttggtaac tatatggtat tcttttaaca
    45001 tcctcgtttg cttcttctaa tttatttata caaagtcaca cttttttaaa catctgttct
    45061 tcgatacatt tctatttctt ttaaacatcg ataccaatat tttgaactta agagtgcata
    45121 ccaaatggat tcatttactc ttcgtcagtt acgaagataa tcaaaatctc caacttccct
    45181 acttatttcg ttttgagaat tatcgaagca atcttacata aataactaaa aaacaaaaaa
    45241 ccagaaaatc agtatactga ttttctggtt ttacatggtt tgttcaataa aaagctgttg
    45301 gaactgttaa tattaaatta tcgcatcgtt acgaattctt ccgctcctgt tggatggatg
    45361 gctactgtat tgtcaaagtc ttctttagtt gcacccatct tgatagccac ggcaaaacct
    45421 tgcagcatct catcgacacc aacaccaata gcatgtaagc cgacgattct ttcttctttt
    45481 ccgacacaga tcaatttcat ttcgcatttt tggcgataat catttaatgc aaagtacatt
    45541 ggggtaaagc gtgaacgata aactttcaat tcattttcgc catatttttc caatgcttct
    45601 tcttctgtca aaccaattgt tgcaattggt ggatgcgtaa agacgactgt cggaacaagt
    45661 ttatagtcaa gataagaatc tttctttcca ttaaataaac gttctgataa acgtctacca
    45721 gctgcgattg caacaggagt cagatctaat ttaccgatca catcaccaac agcaaaaata
    45781 tgttcatccg ttgtattttg gtatttatct actttgataa accctttttt gtccaattcc
    45841 acatttgtat tttccagacc taatttttcg gtattcggta cacgtccacc ggcaaaaagt
    45901 acacaatcac cagttaaggt ttcaccattt tcaaatagca ccgtatattc gtcattgttt
    45961 ttagtaattt ctttagcaat atgatgtgcg taagttttta ttccagcttc ttggtacatt
    46021 tggatcaaat tgtccgaaag cattttatca aacgttctaa gtggtcgttc ttttcgatat
    46081 gcccacatga cttcactacc taaaccacga aatacacctg aaagttcagc cgcaatgtat
    46141 ccagcaccta aaacgattgc tctcttaggt aactctgtta attcaaaaaa tccatttgaa
    46201 tcaattgcgt attctccacc aggaatggtc attttacttg cacggcctcc agtagcgatc
    46261 aagattttag gagcacgata ggtttcaccg tttacttcga tcgtttgact atcgataaaa
    46321 gtagcgtaac cttttatagc ctcgacatga ttgctatcta atcctctttg ataagcaccg
    46381 tgtagaaaat caatatattt ttctcgtctt tctactagac cggcgaaatc aacatttttt
    46441 aaatctgctt ggataccgta acttgaggca tctcgttcaa ttgtttccaa aatcgtactt
    46501 gcttgccaca taactttttt aggtacacaa ccgacgttga cacatgttcc gcccaattca
    46561 ttcgcttcaa tcagcaaaac ttttgcgcca tgcatccctg ctctgtttgc tgaagcaata
    46621 ccgccagagc cgccaccaat tacgatgtaa tcatatattt gcattttgtt cctccttatt
    46681 gaagagatca atcaaaacct ttatttaacg atcctttttc tacagaaaac aagtgtaaca
    46741 cttttcttga attttgtatg cgaagatgct taaaacaggg atatatcagc tttttcctta
    46801 tttacgtttt cggatcatat ctccaggttt caccggctgt gcgactggca tagttaaaat
    46861 catcattgga tttggtgctc ggtcaatgga ttcgccttct tcattatgca taacttcaac
    46921 ggtttgactg aaatgactga atcctggacc ataaaattcg atttcatctc ctacagaaaa
    46981 caagtttctc tgacgtatcg tagcaatctg tgttgcctca tcataagata atacttcacc
    47041 gacaaattta tatactggga ttttacgatg ttcaccgaat aattgttcgt tttcagttgg
    47101 tgtattgtag taaaaacctg tagctaattc tcgttgtgct actttccata actcgtcgat
    47161 ccattcttgc ttgcagacat agttttcagg atcttccata taactgtcta cagccgcttt
    47221 atagacattt gacaccgtag atacataatg gatcgatttc attcttcctt cgatcttgaa
    47281 gctgtctacg ccgttttcaa tcaattctgg aatatgttcg atcattgaca tatccactgc
    47341 actcatcgag aattcttctt ccacttcgcc tgtatcagtt aaactgtttc gttcttgacc
    47401 aaaaggcata tcgaacaatc catacttcca gcgacaagat tgagaacatc cgccacggtt
    47461 tgcatcccgc atcgacatat ggttggacaa tgtgcatcga ccagaataag agatacacat
    47521 ggcaccatgg ataaatgctt cgatttcggt atccgtattt ttacgaatct ctgccacttc
    47581 ctccattgaa acttcacgag ctaaaacgac acgttccaac ccttcttctt tccagaattc
    47641 caatgtctca aaattagttg ctgaagcttg agtggataaa tggatcggca gacctggggc
    47701 ttctgtcgca caaatttcga tcaaagctgg atcagaaaca atcactgcag aaataccgac
    47761 atcacgcaaa ctgcggaaaa attcccctgc tccatcttca tttccttcat gggtgaccat
    47821 attagcagca acgtatacct tcgcatcatg ttcttttgca aaagcaactc cttcagccat
    47881 ttcttcataa gtaaaattac ctgcacggct tcttaaacca tatgcattcc cgccaatata
    47941 tactgcatct gctccataat ggatcgcggt ttttaacttt tccagtgttc ctgctggcgc
    48001 taggatttct ggtcgtttca attttctttt tactgtcatt tctttcatca tactccttat
    48061 ttgatagcag aaggatcaat ataaaagaat cctgtatcta attcacggtt ttcaggatgc
    48121 aatttactga tttcgctagt cattttttcc gctttttctt gatcccagct accttctaaa
    48181 atttgttttt ttgcttcggc gaatagtcga gtgatgttta cgaatttttc gcctggagta
    48241 aataatccgt ccaatttcca tgtacagtaa tgatgctgat aaagttcatt caattcattc
    48301 gagagattca gatcattgct ggcaaaaata tgtgtgccat gactatcttc ataaatagaa
    48361 taatgtgtct cttctttttt aggttccgag ataaaaagac ctctttcacg atctttttgt
    48421 tcgtcttgtt tcgtatagtt atagtaattc tgtagcagtg gacgtttgga ttgatggatg
    48481 catgtagcac catacacaag ggtttctaca ggaatatcga gtttttcttc catcgccttc
    48541 atctcttcaa aaggaacttc acgagcaagt actgctccaa ctgcgccttt tttcgcccag
    48601 aaattgattt gacgtgcgct cgttactaat gtttcagcat cataaatata cggtatacgc
    48661 aattcaggat tttttttcat cgtataaata atacctgtat caccaactgt gatcacatct
    48721 acgtttattt cttttaaaaa agccaaatat tcaggtacat ttttcatttt ttcaggatga
    48781 atgatcccat ttacagcaat attcgctttt ttaccatact tgtgtgctaa ttctaccaat
    48841 tgtcgctgtt cttctcgtgt aaatgaagca ggcagacgca atccaaattg ctcttcaccg
    48901 aaatatagtg tatctgcacc tgcagcaagc aactgttctg cttgttcaat agtttctact
    48961 gtggttatga gttcgatcat aattttctcc tcctacaact tcataatagt agcatagctc
    49021 taaaaacttt ccaatacttc ttctatttaa agtcggattt ttgaaaatta tttcacaaaa
    49081 aatcaaaata aagttcgata tattctgtcc aaatataaaa agagattgtg acaaaaatct
    49141 tgtcacaacc tcttaatcaa gtcttactat tataaaaatt cagctacaca ggccaagtaa
    49201 ctatagggaa cctactgttt cctttttagg tccgcgaaca ttcaatgtga tcttaccttt
    49261 tgaagcacct actgttacgt ggtcacctaa acgaatttct ccgccaagca aagcctcgct
    49321 caatcgatct tcaatttctt tttgaagtgc gcgacggatt ggacgtgcac catattcagg
    49381 atcaaatcca gctttcccga tcacatcgat tgcagatggt gtgattttca cttgaatatc
    49441 ttgttctttc aatcgtttga taatcgcttt gctcatgatt tggacgattg tatggatttc
    49501 atctttactc aatgaatgga agacgacagt ctcatcgatt cgattcaaga attcaggtcg
    49561 gaaagctttc tttaactctt ctaagatacg tttttgcatg gctttgtgat ctttagtaac
    49621 atcttggaca ttgaatccga catttttttc ttctcgaatt tgtgtcgctc cgatatttga
    49681 agtcataatc atgattgtat ttctaaagtc cacttttcta cctttagaat ctgttaaatg
    49741 accatcatcc aatacttgca gaagtaaatt gaaaacgtct ggatgtgctt tctccacttc
    49801 atctaagaga atcactgaat atggtttttg acgaattttt tctgtcaact gtccaccttc
    49861 atcataccct acgtatcctg gaggagaccc gattaatcgg cttgtactgt atttttccat
    49921 aaattctgac atatcaacac ggatcagggc atcttcactt ccaaacatga cttctgaaag
    49981 tgctttggcc aattctgttt ttccgacacc agttggtcca aggaacatga atgaaccaat
    50041 tggacgatca ggatctttca atccgcttcg tgcacggcgg atcgcacgtg aaactgcttt
    50101 gacagcctca tcttgaccaa cgacacgttc atgcagaagt ccttccagtt ctaacaagcg
    50161 ttcgctttct tttttctcca actgctgtag agggacacca gtccactccg atacaactgt
    50221 agcaacatct tcttctgtta cacgatcaga ataaccttgc tcctgttttg cttcaattgc
    50281 agaaactttt tgcagctttt tacgtagtgc tttttcttgt ctgcgtaatt gagcagcatt
    50341 ttcaaagtct tgtttttgga tcgctgcttc cttttcttgt actagttcat cgatttctag
    50401 tttgatcaca gttgattttg ttaagtgatc ggtttgatcc aaacggactt tcgctgctga
    50461 ttcatcgatc aaatcaattg ctttatcggg tagttgacga gaagtgatat aacgaacaga
    50521 aagattgact gctgctcgta cagcttcatc tgtgatctcc actccatggt gctcttcata
    50581 tcttgtacgt aatccttgaa gaatcacttc tgcttcttca ggagttggct catctacttg
    50641 aatgcgagca aaacgtcgct ctaatgcaga atctttttcg atatattttt gatattcatc
    50701 tagggtcgtt gctccgatcg tttgtaattc tcctcgagct aacgccggtt tcaagatatt
    50761 cgaagcatca attgctcctt ctgctccacc tgcaccaatt aaggtatgca attcatcaat
    50821 gaataagatt acttgaccat cattatagat ttcgtcgatg acctttttca ttcgatcttc
    50881 aaattcaccg cgatatttcg taccagcaac caaagatccc atatcaagca tcatcaggcg
    50941 cttttcttgc atgtcttctg gcacttcacc taaaatgatt ttttgagcta acccttcagc
    51001 aatggctgtt ttgcctacac caggttcacc caccagtaca gggttattct ttgtccgtcg
    51061 gctaagaatc tggataagcc gtttcacttc tctcgaacga ccaacaactg ggtccagctt
    51121 gttttctttt gctaatttcg tcaaatcacg tgctaatgaa tctagcgtag gtgttccttg
    51181 cggtgtttgc cgtttatctt gtacatttac atttctacga cgattcattc cttttccagc
    51241 agaatcacca gctagcccca ttttttgttt cagaacttga cgggcttttg aaaggctgat
    51301 acctaagttg atcatgattc gagtagccat gatactttca tcttttaata agctcatcaa
    51361 aatatgttct gttccaactt tttgagaacc agttttcttc acttcgctgc tagctaaagc
    51421 aaaaacttgt ttcattcttg gtgaatatgg aagaaagact cctttagggt aagaacggat
    51481 accaccataa ccaatcagat gttcaatttc ttcataaatt tccgtttcat tcaaatccat
    51541 ttcacgtaat acttttccag caattccatt ttgctcgacc actaaggcta gtaaaacatg
    51601 ttctgaacta actgattgat gtttcaaccg ttttgcttct tcttgtgcaa tttctaatac
    51661 tgcttgggct ctttcagtaa aaagttcttc catctaatct cacttcccat cttcataact
    51721 taaacgttcc agaaatgctc ggagaatccg agcacgtgta tgatcttcat attcattgaa
    51781 attcaatgtg ttttttgcaa ttgcactcaa catcaagttt ccttcttttt ttgtaattat
    51841 ttggtcttca taaagttttt gaataatagc aaaagcattt ttctcactga ttgtatcatc
    51901 aaataactga tttatctgct caagtaattg ttttttatct gaaatcctta cttttgcaat
    51961 tcgtatataa ccaccaccac cacgtttgct ttctactaga taaccacgtt ggatggtaaa
    52021 acgggtatta atcacatagt tgatttgtga aggaacacag ttaaagaggt ctgccatttc
    52081 aatccttcga atctcgatca tttcactatt ttccagaatt ttctttatat atgattcaat
    52141 taaatccgag gtattctgat gtgccatctt attcattccc tttgactaat attgacctta
    52201 attataacga atttgataat agaaagaaag aagaacgctt tttgttaaat aaatccttta
    52261 gaatcaacaa aaaaaaaata cggaatatac tattccgtat cgacgcgccc aagaggagtc
    52321 gaacccctaa ccttttgatc cgtagtcaaa cactctatcc agttgagcta tgggcgcata
    52381 ttcaatttaa aaaaattata aatcatttga aaacaaaaag caagataaaa aaaatcggga
    52441 agacaggatt cgaacctgcg accccttggt cccaaaccaa gtgctctacc aagctgagct
    52501 acttcccgtt taaaaaataa aaaagac
//
LOCUS       DASHWW010000012        51328 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.012, whole genome shotgun sequence.
ACCESSION   DASHWW010000012 DASHWW010000000
VERSION     DASHWW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.012"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            330..1175
                     /locus_tag="U2R64_000850"
     CDS             330..1175
                     /locus_tag="U2R64_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8917688.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="U2R64_000851"
     CDS             1456..2676
                     /locus_tag="U2R64_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HEM8917689.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="U2R64_000852"
     CDS             2673..5393
                     /locus_tag="U2R64_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8917690.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="U2R64_000853"
     CDS             5377..6321
                     /locus_tag="U2R64_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8917691.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="U2R64_000854"
     CDS             complement(6390..7400)
                     /locus_tag="U2R64_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8917692.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="U2R64_000855"
     CDS             complement(7580..7924)
                     /locus_tag="U2R64_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEM8917693.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="U2R64_000856"
     CDS             complement(7917..8351)
                     /locus_tag="U2R64_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEM8917694.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="U2R64_000857"
     CDS             8489..9226
                     /locus_tag="U2R64_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917695.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="U2R64_000858"
     CDS             9219..10430
                     /locus_tag="U2R64_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917696.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="U2R64_000859"
     CDS             10634..11416
                     /locus_tag="U2R64_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEM8917697.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="U2R64_000860"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="U2R64_000860"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEM8917698.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="U2R64_000861"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="U2R64_000861"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HEM8917699.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="U2R64_000862"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="U2R64_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEM8917700.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="U2R64_000863"
     CDS             15018..16067
                     /locus_tag="U2R64_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HEM8917701.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="U2R64_000864"
     CDS             16064..16342
                     /locus_tag="U2R64_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEM8917702.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="U2R64_000865"
     CDS             16317..16787
                     /locus_tag="U2R64_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEM8917703.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="U2R64_000866"
     CDS             16804..17106
                     /locus_tag="U2R64_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917704.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="U2R64_000867"
     CDS             17123..17494
                     /locus_tag="U2R64_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HEM8917705.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="U2R64_000868"
     CDS             17466..17825
                     /locus_tag="U2R64_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917706.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="U2R64_000869"
     CDS             17997..19004
                     /locus_tag="U2R64_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8917707.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="U2R64_000870"
     CDS             19029..20213
                     /locus_tag="U2R64_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEM8917708.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTMMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="U2R64_000871"
     CDS             complement(20650..22233)
                     /locus_tag="U2R64_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8917709.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="U2R64_000872"
     CDS             complement(22811..22954)
                     /locus_tag="U2R64_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEM8917710.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="U2R64_000873"
     CDS             complement(23177..23656)
                     /locus_tag="U2R64_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8917711.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="U2R64_000874"
     CDS             complement(23729..24013)
                     /locus_tag="U2R64_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917712.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="U2R64_000875"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="U2R64_000875"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="U2R64_000876"
     CDS             complement(24357..25643)
                     /locus_tag="U2R64_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEM8917713.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="U2R64_000877"
     CDS             25781..26452
                     /locus_tag="U2R64_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HEM8917714.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="U2R64_000878"
     CDS             26418..26906
                     /locus_tag="U2R64_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEM8917715.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="U2R64_000879"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="U2R64_000879"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEM8917716.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="U2R64_000880"
     CDS             27867..28631
                     /locus_tag="U2R64_000880"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEM8917717.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="U2R64_000881"
     CDS             28864..31077
                     /locus_tag="U2R64_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEM8917718.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="U2R64_000882"
     CDS             31088..31534
                     /locus_tag="U2R64_000882"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEM8917719.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="U2R64_000883"
     CDS             31705..32964
                     /locus_tag="U2R64_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HEM8917720.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="U2R64_000884"
     CDS             complement(33053..34000)
                     /locus_tag="U2R64_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8917721.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="U2R64_000885"
     CDS             34394..35686
                     /locus_tag="U2R64_000885"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEM8917722.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="U2R64_000886"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="U2R64_000886"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEM8917723.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="U2R64_000887"
     CDS             37579..38454
                     /locus_tag="U2R64_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8917724.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="U2R64_000888"
     CDS             38720..40603
                     /locus_tag="U2R64_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEM8917725.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="U2R64_000889"
     CDS             complement(40678..40962)
                     /locus_tag="U2R64_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEM8917726.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="U2R64_000890"
     CDS             complement(40952..41686)
                     /locus_tag="U2R64_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEM8917727.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="U2R64_000891"
     CDS             41815..42438
                     /locus_tag="U2R64_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEM8917728.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="U2R64_000892"
     CDS             42630..43751
                     /locus_tag="U2R64_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HEM8917729.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="U2R64_000893"
     CDS             43758..46886
                     /locus_tag="U2R64_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEM8917730.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="U2R64_000894"
     CDS             46905..50099
                     /locus_tag="U2R64_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEM8917731.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="U2R64_000895"
     CDS             complement(50245..50952)
                     /locus_tag="U2R64_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEM8917732.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16801 a         8959 c        10646 g        14922 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaatgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcac tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgctatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttata
//
LOCUS       DASHWW010000013        48011 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.013, whole genome shotgun sequence.
ACCESSION   DASHWW010000013 DASHWW010000000
VERSION     DASHWW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.013"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(22..1806)
                     /gene="pyk"
                     /locus_tag="U2R64_000896"
     CDS             complement(22..1806)
                     /gene="pyk"
                     /locus_tag="U2R64_000896"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEM8917733.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(1880..2842)
                     /gene="pfkA"
                     /locus_tag="U2R64_000897"
     CDS             complement(1880..2842)
                     /gene="pfkA"
                     /locus_tag="U2R64_000897"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEM8917734.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKIGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(3010..6324)
                     /gene="dnaE"
                     /locus_tag="U2R64_000898"
     CDS             complement(3010..6324)
                     /gene="dnaE"
                     /locus_tag="U2R64_000898"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEM8917735.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKIDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            6555..6740
                     /locus_tag="U2R64_000899"
     CDS             6555..6740
                     /locus_tag="U2R64_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HEM8917736.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(6802..7998)
                     /locus_tag="U2R64_000900"
     CDS             complement(6802..7998)
                     /locus_tag="U2R64_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEM8917737.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(8168..9604)
                     /locus_tag="U2R64_000901"
     CDS             complement(8168..9604)
                     /locus_tag="U2R64_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEM8917738.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            9897..10706
                     /locus_tag="U2R64_000902"
     CDS             9897..10706
                     /locus_tag="U2R64_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8917739.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(10892..13045)
                     /locus_tag="U2R64_000903"
     CDS             complement(10892..13045)
                     /locus_tag="U2R64_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEM8917740.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(13440..14288)
                     /locus_tag="U2R64_000904"
     CDS             complement(13440..14288)
                     /locus_tag="U2R64_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8917741.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(14512..16452)
                     /gene="thrS"
                     /locus_tag="U2R64_000905"
     CDS             complement(14512..16452)
                     /gene="thrS"
                     /locus_tag="U2R64_000905"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEM8917742.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(16789..16968)
                     /locus_tag="U2R64_000906"
     CDS             complement(16789..16968)
                     /locus_tag="U2R64_000906"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEM8917743.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(17015..18838)
                     /gene="cadA"
                     /locus_tag="U2R64_000907"
     CDS             complement(17015..18838)
                     /gene="cadA"
                     /locus_tag="U2R64_000907"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEM8917744.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            19116..21395
                     /locus_tag="U2R64_000908"
     CDS             19116..21395
                     /locus_tag="U2R64_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8917745.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(21488..22135)
                     /locus_tag="U2R64_000909"
     CDS             complement(21488..22135)
                     /locus_tag="U2R64_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917746.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(22314..23033)
                     /locus_tag="U2R64_000910"
     CDS             complement(22314..23033)
                     /locus_tag="U2R64_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8917747.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(23164..24315)
                     /locus_tag="U2R64_000911"
     CDS             complement(23164..24315)
                     /locus_tag="U2R64_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEM8917748.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(24532..25272)
                     /locus_tag="U2R64_000912"
     CDS             complement(24532..25272)
                     /locus_tag="U2R64_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8917749.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(25276..25599)
                     /gene="rsfS"
                     /locus_tag="U2R64_000913"
     CDS             complement(25276..25599)
                     /gene="rsfS"
                     /locus_tag="U2R64_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEM8917750.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(25656..26249)
                     /gene="yqeK"
                     /locus_tag="U2R64_000914"
     CDS             complement(25656..26249)
                     /gene="yqeK"
                     /locus_tag="U2R64_000914"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEM8917751.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(26233..26883)
                     /locus_tag="U2R64_000915"
     CDS             complement(26233..26883)
                     /locus_tag="U2R64_000915"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEM8917752.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(26893..27204)
                     /gene="yhbY"
                     /locus_tag="U2R64_000916"
     CDS             complement(26893..27204)
                     /gene="yhbY"
                     /locus_tag="U2R64_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEM8917753.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(27220..28329)
                     /gene="yqeH"
                     /locus_tag="U2R64_000917"
     CDS             complement(27220..28329)
                     /gene="yqeH"
                     /locus_tag="U2R64_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEM8917754.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVGAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(28326..28853)
                     /locus_tag="U2R64_000918"
     CDS             complement(28326..28853)
                     /locus_tag="U2R64_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEM8917755.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(29033..29818)
                     /locus_tag="U2R64_000919"
     CDS             complement(29033..29818)
                     /locus_tag="U2R64_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEM8917756.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(29811..30680)
                     /locus_tag="U2R64_000920"
     CDS             complement(29811..30680)
                     /locus_tag="U2R64_000920"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEM8917757.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(30681..32060)
                     /locus_tag="U2R64_000921"
     CDS             complement(30681..32060)
                     /locus_tag="U2R64_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEM8917758.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(32068..32487)
                     /gene="fabZ"
                     /locus_tag="U2R64_000922"
     CDS             complement(32068..32487)
                     /gene="fabZ"
                     /locus_tag="U2R64_000922"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEM8917759.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(32512..32988)
                     /gene="accB"
                     /locus_tag="U2R64_000923"
     CDS             complement(32512..32988)
                     /gene="accB"
                     /locus_tag="U2R64_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEM8917760.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(32991..34226)
                     /gene="fabF"
                     /locus_tag="U2R64_000924"
     CDS             complement(32991..34226)
                     /gene="fabF"
                     /locus_tag="U2R64_000924"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEM8917761.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(34245..34982)
                     /gene="fabG"
                     /locus_tag="U2R64_000925"
     CDS             complement(34245..34982)
                     /gene="fabG"
                     /locus_tag="U2R64_000925"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEM8917762.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(34994..35911)
                     /gene="fabD"
                     /locus_tag="U2R64_000926"
     CDS             complement(34994..35911)
                     /gene="fabD"
                     /locus_tag="U2R64_000926"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEM8917763.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(36018..36242)
                     /locus_tag="U2R64_000927"
     CDS             complement(36018..36242)
                     /locus_tag="U2R64_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEM8917764.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(36295..37257)
                     /locus_tag="U2R64_000928"
     CDS             complement(36295..37257)
                     /locus_tag="U2R64_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEM8917765.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(37267..37707)
                     /locus_tag="U2R64_000929"
     CDS             complement(37267..37707)
                     /locus_tag="U2R64_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8917766.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            38013..38978
                     /locus_tag="U2R64_000930"
     CDS             38013..38978
                     /locus_tag="U2R64_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEM8917767.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(39035..39265)
                     /locus_tag="U2R64_000931"
     CDS             complement(39035..39265)
                     /locus_tag="U2R64_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEM8917768.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(39351..40238)
                     /locus_tag="U2R64_000932"
     CDS             complement(39351..40238)
                     /locus_tag="U2R64_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEM8917769.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(40327..41550)
                     /locus_tag="U2R64_000933"
     CDS             complement(40327..41550)
                     /locus_tag="U2R64_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8917770.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(41567..42613)
                     /locus_tag="U2R64_000934"
     CDS             complement(41567..42613)
                     /locus_tag="U2R64_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8917771.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(42777..44504)
                     /gene="ptsP"
                     /locus_tag="U2R64_000935"
     CDS             complement(42777..44504)
                     /gene="ptsP"
                     /locus_tag="U2R64_000935"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEM8917772.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(44504..44770)
                     /locus_tag="U2R64_000936"
     CDS             complement(44504..44770)
                     /locus_tag="U2R64_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEM8917773.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            45249..47483
                     /locus_tag="U2R64_000937"
     CDS             45249..47483
                     /locus_tag="U2R64_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8917774.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQKAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            47631..47951
                     /locus_tag="U2R64_000938"
     CDS             47631..47951
                     /locus_tag="U2R64_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEM8917775.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        13694 a        10311 c         8405 g        15601 t
ORIGIN      
        1 tttatttttt attaagctaa attagatagc tgttgtttcg ccacggtaaa cgatgccgcg
       61 acgtgaatca acggtaatca attcaccttc tgtaattgtt gttgttgcgc ctttagcacc
      121 aacgattaca ggaatatctt gtgcaattcc tacaactgca gcgtgagaag tcaatccgcc
      181 ttcttcaacg ataacagcag ctgctttttc gattgcaggc atatattctt tgtcagttga
      241 tggtacaact agaaccattc cgtcttttgc tttttttaca gcttcttcag cagatgaagc
      301 aataactgca tttgcaacga cagatttttg tccaacgcct tgagcttcta ataatttaga
      361 accaatcatt tgaattttca tcacgttagt tgttccgcgt tcaccaactg gtacaccagc
      421 agtgatcaag attaaatcgc cttctgatgc gaaacctaat tcaacagctt ttttagctgc
      481 tagttcaaac atttcatcag ttgttgatgg tttttcagca actgttgggt aaacgcccca
      541 gtttaacatc aaaccacgtt ttgtgcgttc gtcaaaagta acagccaaga tatctgcatc
      601 tggacgatat tttgaaatca tttttgcagt gtatcctgat tcagttgcag caacgattgt
      661 tttcacgcct agattttttg cagcacgagc tacagataaa ccgattgttt cagttacatc
      721 tgttttatcg aattcgttca attggaatgt acctaattct gataatgcat tttcagcttc
      781 ttggtcgata cgtgccattg ttgaaacagc ttcaactggg tagtccccgt ttgcagattc
      841 accagatagc attgttgcat ctgtgccatc aaatacagcg ttagcaacgt cagaagcttc
      901 cgcacgtgtt ggacgtgggt tttcttgcat tgattctaac atttgtgtag cagtgataac
      961 tgggatacca gcagcattac attttttgat aatgcgtttt tgaaccattg gtactagttc
     1021 agctgggatt tcaacaccca tatctccgcg ggcaatcata acaccgtcag aaactttgat
     1081 gatttcgtca atgttgtcga taccttcttg agattcgatt ttagggaaga tttgaacatg
     1141 agtcatgtct ttttcttcta agatttcgcg gatatctaga acgtcttgtg ctttacgtac
     1201 aaaacttgca gcgataaagt cgatatcgtt gtctaaacca aaacgaatat cgtcagcatc
     1261 ttttggagta atacctggca aactaataga aacgcctggt gcatttaccc ctttacgtga
     1321 tcctagcata cctgcatttt taacttctac gactaattca cggtttgctt cgtctttttc
     1381 aatgatttgc atatcgatca aaccatcatc aaataaaatg tgtccgccaa cgtgaacatc
     1441 gtcaaataat cctgggtaag taaccgcgat tttttctttt gaacctacat gttcaggatc
     1501 catagagatg cgtgtttgat ctcctacttc aaatttgatg tatcctgcac gaccaaaatc
     1561 agcttctgtt gtgccttgaa cagttgtacg gatttcagct ccttttgtat ctaaaagaat
     1621 accgacatct tttcctgtct ttttaactgc ttcacggacc atagtcatac gtgataattg
     1681 ttcttcatgg tcaccatgag aaaaattaaa gcggaagaca tttgccccag attcaatcaa
     1741 ttgagaaata atttctactg agttacttgc tggtcctaat gtactaacga ttttggtttt
     1801 tttcatttaa aaaactctcc cattcaattt tgtttattta aagctgtaca cagcttaaat
     1861 agcttggttt ctttcactct taaaatgaaa gtgaattatt tagatcatat agtgataagt
     1921 ctggtttatg tttgttgttt tcaagtgtat caatgatgtc agacgcaacg atttcgttgt
     1981 catggatacc gacacataat ccaccttttc cttcttgaag caattcgaca gcgtaagcac
     2041 cgaatttact tgccaacacg cggtcgcgtg cgcttggtgc tccaccacgg acaacgtgtc
     2101 ccaagataga tacacgtgta tgatagtcac caaattctga aagtttctca gcgaattcat
     2161 ttccgcccat tacaccttca gccaagatga tcaagcaatg tttcttcccg cgatcgcggc
     2221 cttcttggat ttttttagca actgaagcca tatcaaaatc atgttctggg atgatgattt
     2281 catccgctcc gccagccaca cctgaccata aagcgatgtc tcctgcattg cgtcccatta
     2341 cttcgataac gaatgtacga acatgagaag tcgctgtgtc acgaatacgg tcaattgatt
     2401 ctagtactgt attgattgct gtatcaaaac cgattgtgaa atcagtccca ggaatatcat
     2461 tatcgattgt tccaggaata cctactgctg ggaaaccgcg ttttgtcaaa gccattgcgc
     2521 catgataaga gccgtctcct ccgataacca ctagaccttc gattccgatt tttttcaatt
     2581 gttcgattcc ttttaattga ccttcttcag ttgcaaattc tggataacgt gcagaataca
     2641 agaatgtacc accacgttgg atcttgtcac ctacatctgc cacatcaaga cgacgaatat
     2701 ctccagcaac taaaccggca aaaccataat tgatcccgta tacttccagt ccttcgtaaa
     2761 tacctttacg aacaacggca cgaacagctg cattcattcc aggtgcgtct ccgccactgg
     2821 tcaaaattcc gatgcgtttc ataataaaca ttcacctcat taaaatactt tatcctaagt
     2881 atgacttagg tttacaacca tttttgcgtt aaccacgact aacattctaa cattattttt
     2941 ctcacttgtc ttgatttacg gataaaaaaa tgaaaaaaaa tgaaagcaag tagtattttt
     3001 taccgtaagt tatttgaaaa ccacattatc ttcgccaagc agataaataa gttgcccctt
     3061 tatactcttg ctgtcatcca cccaataagc atctgacaga actacttttc gttgcgtttt
     3121 ttcgtgatac ataactactg gtatatatcc tgggtgtttc tgaaaaatca cttgtaattg
     3181 tttcattatc tcgggatctt cccgttcttc tgtaatacgc aaatagcaag tttgtgaagg
     3241 atactgggct tctaactggt taggatcagc aaagctttct ccaattagtt gcagttcctg
     3301 attatatttg ctgatttcgc tccgcccttg aacaaagatc actcgatcaa cggcaaacaa
     3361 attacgatat ttacgataaa gagttggaaa aactgtgaca gaaatttctc cactactgtc
     3421 ggttccttca acaaaggcca tcagttctcc tttttttgtc cgaatttctc taacttcctt
     3481 gatcatcact aataaattga ctggttgatt agggacgata tctgtaatca gctgaacttg
     3541 tttagctaaa cgaagacgat caaacccttc tgcaggatga cctgacaaat aaatacctaa
     3601 gtactcctct tccagcttca agcgttcttc tagtgtatag tcagcgactt cttcttcttt
     3661 taatgccatg attcccagca agtcaagact tccaccactg taaacgatat tttggatttt
     3721 tccttcgaga tcaagcatca attgtttcct gttaggagat aattcatcaa aaactcctac
     3781 tgctgtcagt gattgcagta actctaattt cagccaacgc ttatcgatcc gtatgaggaa
     3841 ttgatccact gactggaacg ggccattttg ttttctttcg tttaatatat cttctacaaa
     3901 atcacgccga atacctttta tcgctgtcag tccgaatctg atttcttcct tattgaccaa
     3961 ctcaaaactg gaattacttt gattaatgga cggcgaggaa agtttgagtt tatttttacg
     4021 tgcttctgca atatattctt tcaattttga tgtgttatgc cgaacagaat tcatcaggct
     4081 ggtaaagaaa gcacctggat gatgggcttt tagatacgcc atttggaatc ccacgaatga
     4141 ataagcaaat gcatgtgacc gattgaatcc atagtttgca aatttttcga tatattcata
     4201 tacggtcgct gctgtttttt ccgaatatcc ctgttgtaat gctcctgata caaaatgcga
     4261 cttttcttca tctaatacgt cttttttctt tttactcact gcccgtcgca gaatatctga
     4321 ctgccctaat gtaaatccag ccatagtcga ggcgatctgc atgatttgtt cctgatagac
     4381 gatcactcca tatgtgtttt tcaaaatcgg gatcagtgaa tcatctgggt agcgaatggc
     4441 ttcttttcct ttcttcctgg caatgaaggt atctatattt tgcatagggc ctggtcgata
     4501 caatgcattg actgcggcaa tatcttcgat gttttctgga tctaatcttc gtaaaacgtt
     4561 ccggatacca gcagattcaa attgaaatac tcctgaggtt tcgcctcgtt gaaacaagag
     4621 cagcgttttt gcatcattta gcgggatctc ttttaatcgg atctcatacc cttctactcg
     4681 cttaacagct ttcaaagtaa aatcaataat cgataagttg cgtagtccta aaaagtcaat
     4741 tttcaaaaga ccgattgctt ctacctcatt catcgtatac tgggtcagaa aagcttcatc
     4801 agaaccgcgt tggagcggaa ctagttcaag tagattctta tcgctgataa ctacacctgc
     4861 tgcgtgagtc gaaacatgtc ttggcaatcc ttctaaaatc actgcagttt tgaataaaag
     4921 ttggtttttt tcgcttgcct gaactaattc tactaattga tgcgaagttt tataagcttg
     4981 ggtcaatgtg attttcaatt gattgggtat tgcttttgac cagcggtttg cttcactttg
     5041 cgataaacca aacactctag ctgcatctct aagaaccatt tttgctgcca ttgtgccaaa
     5101 tgttgcgatt tgtgccatat gatattgtcc atacttttct cgaacataat tcaatacttc
     5161 ttcacgtcga ttgtcaggaa tatccaaatc gatatctggc atcgtaaagc gttcggggtt
     5221 taaaaagcgt tcgaacagca aatcatattc taatggatcc acatctgtga tttctaacac
     5281 ataggctact aatgaacccg cagcagaacc acgacctgca ccggtaacga ttttgtttct
     5341 atgagcaaaa gccattacat cccatacgat caagaaataa tcatcgaatc ccatttgatg
     5401 gatgacagat aactcgtagt ccaaacgttc ttggtattcc tttgtatagt cagtgattcg
     5461 gcgttccact tgcgaatagc ataactctct taaatattct ccagcttgtt ttccattagg
     5521 aactggataa tgcggaagta atttctgatg gaactggaat tcaaatgaaa tcgattcagc
     5581 taaacgctgg gcgcctatta cagcttggga aagacccgct ttttcgaatc gtttgatcat
     5641 ttcttgttct gaaagaagat agacatttgc tgttagtggt aaagatgcag ataaattttc
     5701 taaaggtatt tggcttccct ctttgatatg tttcatcact tcaagtgcaa aaagttcttc
     5761 ttgttgtaaa ctagcgatgg gatgtaatgc acaaagcgaa taattttctt ttatcacata
     5821 ctgataccat tcaggcaatt gatcaggcgt gttttctgtc aagccgatat aaaaatttct
     5881 agtaaaaaca ttttcaagta aaaactgcca atgaccgaaa aagttatcct ctttattgaa
     5941 agcctcagaa acagaatgat ttgccggaac aacaaacgct agatggtcgg tttctgtcat
     6001 ttctgcaagt tccaattttt cttggatcat ttttcggctg gaaagtttca tcagctgctg
     6061 ataacctatt tcatcttttg cgtacgcaag caagccataa tttttttctt cataagtata
     6121 actaagatgt aatccaatga ttggctgtac tccttcttct acacaaatac gatagaattc
     6181 aggtgcaccg tataagacat ctttatccgt tatggctaat gaagtgtagc cttgtttttt
     6241 tgcttcttgt acatattctc gaatacgtat cgtactttgt aaaagagaat aagaagtaat
     6301 tgtataaagt tgtgggaaaa acatcttgca ttccgccttt tttttcgtta aaattcacta
     6361 gcgttaaaag gtttgatcct tttactttca ttaagatagc aggcgctgaa gttgattatt
     6421 ccacttcatt tgcttgcttg taatctgtag gaatgagttc tttcgcaaga actcaaattt
     6481 tattgagatt tggtctcgtt tctttacatt caaagaaaat ctggtaaaat taagatagaa
     6541 aagaggtgtt ctttatgcga tatatcgtta cattattctg ggctgtcgtt ctaggtcaag
     6601 tagtcggtta tattggtgct gcattaacaa gcggaacata tgattttact ttgacaacaa
     6661 tcatttcatt cattgcgggt gtcattatcc ttttgattgg tgcagttgcg ccaagaaaag
     6721 aaacctctgc ccattcgtaa aaaaacagcc aagagcttga gatttctcaa gctctttttt
     6781 attttctact cctcaccacc attataatct gctgcgaaga actttacgaa agttgaataa
     6841 agaaagaaga atatttgaca gaacaaacaa acttgtcaca ataaaaacag cactgtaatt
     6901 ataagcatgc gcgactgtcg atcctagcat gggacctaaa acttgtccaa agttgctaaa
     6961 catctgattg tagctataga ttcggctgac tccttcttga ggcgtaatct tactgatcag
     7021 tgtattgaca gaaggcatca aagcgccagt tgaaaagcct aaaataaagc gaagtatacc
     7081 taattggagc ggtgtagtga cgaatgccat aggtaaataa cagcaaaatg ataaaatgag
     7141 tcctccaatt agaacttttt gattcccaat cttatcccct agttttccta gtttcggtga
     7201 agaaaagaca gcggaaacac cagctatcga aacaatcaag ccgctgacaa aaaggatatt
     7261 ttctgtactt ccgctcaatt cacgaatata taaggtcaaa atagggctga tcgtagtgat
     7321 tcctatctgt aaaatcaagg tcgtaatgaa gagaccgatc aaaatagaga gatgatccat
     7381 ttttgaaaaa atttctttgg tgcttatcag atcttttttc tcgattggat ggaaatcttc
     7441 tttgactaag aaaatggtca ataccgttgt gatcatcaac aaagcccctg tgatcaagaa
     7501 tacattttcc ataccaaacc actgagccag tgcaccgccc attgaaggtc cgatcagatt
     7561 tccagcaatc gctccggtag acaatgttcc taacgcccat ccgctctttt ctctaggtgc
     7621 ctgtgaagca atcatcgctg tggcatttgg aatatatcca gacaaaatcc cattccaaaa
     7681 ccgcatgatc aaaagccaat acgcgtttgg tacaaaagcc aaagatccca ttgttaatgt
     7741 catccctgct gctgcacgga tcatcatgag ttttcggcct tttcgatcag ctagatttcc
     7801 ccagattggt gcaaccacgg cagatgcaaa agcagtcaca gagattgcta gtcccgaaaa
     7861 caattcgatt tgatcttttg gtgttcctag ttgctcaaca taaactggta tgaatggcat
     7921 aactaaacta atacttgcac cagtgaaaaa acagccaatc cacgcaatca ctaaattttt
     7981 tctccaatta atctccatct atcatccctc tttcgtctct tttatcatac ctattttcga
     8041 ataaacaagc aacgatctcg ccagtaaaaa gagaaaaatc ccgcaaaggt cattttatat
     8101 gtaacgttct ttttatgtaa aacaaaaaga gatcagaaca aatactgttc caatcccttc
     8161 tctttagtta aattgttgct agaatgatga agttgataat gaataaaata tcaacgatcc
     8221 acaaagcaac agaaacttga ttgtattttc ctttgattac tttcacaatt gtatagaaaa
     8281 taaatcctgc tgcaatccca taggaaatgc tatagcacaa tcccataaag atcgatgcaa
     8341 agaaggccgg taaagcttct tccatatcta gccatttgat gtctgcaaaa gaagccatca
     8401 tcattactcc aactaaaatc aatgctggcg cagttgcttg atttggtaca atggcgatca
     8461 gtggagagaa taaactactt aatgcgaata gcactgccac tactactgaa gtcaaaccag
     8521 tacgtccacc ggccccgatc ccagctgcag attcgacata agttgttgta ttcgatgtac
     8581 caaagatagc ccccacagaa gtagcgatcg catcggcaaa tagtgcttta tccatttttg
     8641 ttttgaaccc acgaccatct tccaacgcga tctcgtcttc ttttgagaaa atacctgtgc
     8701 ggcgtcctgt accgataaat gttccgatcg tatcgaaagt atcagataaa ctgaatgcga
     8761 tgatcgtcat caatacttga ggaatcttgg aagaatcact gaataaagat tgcatgcctt
     8821 cagaaccaaa tgctgcaccg aaagttgttc ctaattcttt aaatgaatta cctaacgaat
     8881 tcgtttgcca atcaatggaa cttaaatcaa caacacccat aaaaatacca aggactgtgg
     8941 tcgctacgat accgataaga atagccccac ggacattttt tacaactaaa atggctgtca
     9001 gtaccaaacc aatcacagcc aataagatag gagcgttgtc aaagttggct aacgcaggga
     9061 cgattccacc atttatcgta acatttgtcg cttttccgcc ttcaacgaca gagctcgaaa
     9121 tagctgactg gtctgctgaa aaagataaga atcctgcatt tttgattccg acatacgcaa
     9181 cgaaaatacc gatcccgcca ccaatcgcat gttgaagact ttcgggaatc gcccgaataa
     9241 tcatttttcg aatatttgtg acagtaataa aaatattgat taatccgcaa ataaacacca
     9301 ttgccaaggc ttgttgccaa gaataaccaa gcccaaaaac gaccgtaaaa gtgaaaaatg
     9361 cgttcaatcc cataccaggt gcctgagcat atggtacatt tgcgaacaat cccattacca
     9421 gcgtaccaat aatcgatgca atgattgtcg ctagaaatac tgcttggaag ggcatacctg
     9481 atgctgacaa aatcgtcgga tttacgaata agatataact catggcaaag aatgtcgtta
     9541 ctcccgccat tatttcagtt gatacatttg tattgttttt ctttaaaccg aaaaactttt
     9601 ccataaaaag ttccactccc tgaatttttt tctgatggaa aactataata ataaaaaata
     9661 agtaaaatag ggcaaatcca tcgaacaatt tcaaattata tagacgtttc attcgctttt
     9721 caacgttttt ttaacaaaaa aagcgaaaat aatacttaac gttcgtgttt agcttatgtt
     9781 tagctattta tatagccata actgtagttt ttgttaggaa tagctgattg ctcttgttaa
     9841 ttacctaaaa tatgctagac taaaacaaat gctagttgag gaaggaagga cccttattga
     9901 ataaaaaatt aattgccatc gatctggacg gaactaccct caatcaagat tcgatgatta
     9961 catctaaaac aaaagagact ctaaaaaaag caatcaatgc cggtcatcat gtcagtattg
    10021 ctacaggacg cccattccga atgagccatc agttttacca acaattagaa ttaacaacac
    10081 cgatggttaa ttttaacggc gcattagtac acatccctaa tcagcactgg gatggtgaaa
    10141 gagaaacgtt gatcaatcgt gaaatcgctt ttgaaatctt atcgcaaaaa aagcagctaa
    10201 atttagattt tatcgctgct gaaaatcgtg atactttttt tattgacagt tttgatttct
    10261 ttgatgaaaa aatttttgct tcttctcgtc caggagagaa gaatttgctt tctcctaaaa
    10321 atttgacgac aaatcctaca tctttgcttg tccgaacaga caaacgtttt gcaggagctg
    10381 tatctgctga attaacacgt caatttggca gttatgtcga tgttcggaca tggggtggac
    10441 ctactgccat cttagagatt gtttcaaaag gaatccaaaa agcaaaaggc gtgcaagaga
    10501 ttgctaacta cctgtctatc gatcaaaaag acgtcattgc ctttggtgac gagcataatg
    10561 atttggaatt gttggattat gcaggttggg gagtagctat ggctaacggt actgaccaac
    10621 tcaaaggcat tgcaaatgat gtcactcctt tgagcaatca ggaagacggt ttagctgttt
    10681 atctggaaaa actacttaaa ctataataga gaattagatt ccacaaaaaa gaggttgtga
    10741 caatttttgt cacaaccttt tttgccgagt aaacggtgtt caaaagccag tttctcggta
    10801 tgaagtcaaa tttaagcaaa aatgtgagaa gctattttca caaaattttt cttcatactc
    10861 gaaactaagc ggctttttca cgacctcttt tttattttgc catgaacata tcataatacg
    10921 cgtccattat ttctttagca atcgtcaagt ttatgtggtc ttgttcgtct aataagttcg
    10981 gcaagacaac actgatggca atttccggat tgtctgttgg tccgtatgcc acgatattac
    11041 tattgactgt cgcaatatct ggatgacctt ccgcaaccgt ttctgcagtc cctgtttttg
    11101 cggaaaggtc cattttcgca ctggctaatg gtttggctgt tgtgtaagga tcggtaccat
    11161 ggacaacttg gtggaatcct tcacggagga tcgccatatt ttctgcagaa atattgaccg
    11221 tattttctac tgttgtgcca atttctttct tcacttcacc caagtttcca ttttcgtcat
    11281 tgccatagat cgctttgact aggtgcggct gtactcgttt cccgccatta gcgactgttg
    11341 aagcatattg agctaattgg attggtgtat atgtgtcaaa ctgtccaaat gccaaatcgg
    11401 taaagttacc tggagcatac cattctttgc cattatccgc attgaacttc ttcatataat
    11461 caacagaacg tgagatccca ggagattcat tcggcaaatc gatcccagtc gttgtaccaa
    11521 gaccaaactc tttgaaagag tctctcaatt gctgataagc tttagcttct tcatctaaac
    11581 taggtagtcc cattccaggt gtatagtcta gtcctaacat ctttaacgcc actttgatca
    11641 tatacgtatt agaagacaat tccgatgctt tgactgcatc aagagcaact tgtccgcttc
    11701 gattaaagac agagcttttt tctgaagcac cttgcagacg aatcggctca tcaatcaaaa
    11761 cttgatttcc gctgatcgcg ttacttgccc agcctgctgt caaagtacca gccttgacta
    11821 cagaccctgg atcaaaggcg ctagtaatcg tgcctaaagc attctcggtg atttctttgg
    11881 aaccttgttc atgactgaaa ccagtcattg ctagcacttc tcctgtctga ggattcatag
    11941 ccactgcata agcaccaggc gaatactgtg ctttgccgtt gttgatcaat gtttgataat
    12001 tccttttcaa aatttcttct acttttgatt ggaattctgc attcatagat aacattaaat
    12061 tagaaccttt ttccccagag aagatttctt tttgattcga aacatttcct tcattatcaa
    12121 gggaaacttc atattgggtt ttggttcctt gcaggacatc ttcatattgt ttttccaaat
    12181 aactttgtcc tacacggtca ttccgagaat aaccttttgc taggtatttc tctgcttcat
    12241 ctgctggaag tccttgcttt tcagtcgtca cactgccaag aatacttttc agtgaacttg
    12301 ctgcattata ttctcgtgtc cagtctgtgc cagtcgaaac tcctggaagt tcagaagcgc
    12361 gttctgccac aacagctaac tcttgatcag taacaccaga gtttttgata tagacagtgt
    12421 ttaattcata tgcactattc atccgtttaa agatggtagc aatttttaat tgctcctcgt
    12481 ttaaattaat ctcatcagct gtgactttat tgaccatcgc actatattgt tcgctgttcc
    12541 ctaattgctt ttcttttgcc gaaagtcttt ttgtggcttc tttcaaatgt ttgggatcag
    12601 ccagccaaaa atctttttta tctctatctg tcagattttc atctaccgga acatcgatca
    12661 gcgagttcag cttcgttgcg atttcaagca aatctttagc cgtaacttgt gttcctctcg
    12721 tatatgtgat ggcctgattc gctttattcg taactaaagc ttttcctgtg gagtcgtaga
    12781 tcattccgcg aggagtactt tcttggaccg taatcgtaga agtagacttc actcgcgcct
    12841 ccatctcttc gccgttcacg atctgcaaat aacccaatct agcaatcaac gcaacaaata
    12901 acgtaaatat aatgaaaaaa agaaaattta agcgaaaagg aacatgggac cggcgaaacg
    12961 ttttgttctt aggttcttgt gcaccttttc ttattttttc taaccaagaa gtatttaata
    13021 tttttttcat aaaatctttc atcatttcct atccttccgc ctatttacat tcatgcttca
    13081 ttgtacccaa aaacttctta ataaacaaga agtatttaat atttttttca taaaatcttt
    13141 catcatttcc tatccttccg cctatttaca ttcatgcttc attgtaccca aaaacttctt
    13201 aataaaaaag aaaaaatggg cggagcaaga aattctttac ctaatttcaa gataaaatca
    13261 actttttgtt tcacagcaat cacttaaagt tacatatcca actatttttt tcattaaaaa
    13321 ataaacttat ttttgaaaat tatgttttct taagtcgtga aacactttga tggatcattt
    13381 atttgtggaa aactacgttt tgttattcta aaaaacttat ataaaaaata gtaaggtttt
    13441 tatttcgaat ccataaaata ttcttggatt gcttctcgtg tttttttcac tttttcgcta
    13501 agcttttcgt ttttagccat atagaaataa aaaatgatat cgatcgtagc aaattgggcc
    13561 aaaagtgaat tagttgccgc acttcgattc gtgatttctt ttggtctaga tgtttgtacg
    13621 agtacatcgg ctatcttgct aagcgggtta tttccaaatt gcgtcaacgc aatgatttcg
    13681 atattcatgc ttttcgccag ctcggctaat gcgactacat ctgcacttct acctgagttt
    13741 gaaacaagcc aaagcacttt ctttttctca ttgctgacaa gttgcgggag caagacgtgg
    13801 atatcttttt caaaaatgat tggcttaccg acacgagacc atttttgcag aatatcttct
    13861 actactaaag aagaggcgcc aaccccatat aaaaaaacag tctctgccga ttccaaacac
    13921 tctacgactt tttggatcgt ttcttcttct agaatatcta ctgtttcttt tatcgctact
    13981 tgtgcattgt taccaagttt gtttttgata gagtaaaagg actcatttgc ttctatatca
    14041 ctaaaacctt catcgattcc agtctgtagt tctgttgaaa tcgtgatttt gaagtccgtc
    14101 agactttgaa aaccgatttt tttggaaaaa cgtacaactg tcggcgcact caacccggaa
    14161 gcttctgcta attcattagc tgtcattgta gggaccttct caatattacc gataatgtag
    14221 ttggccaact ttttttctgc tgaagaataa tcttccatca tactttcaat acgactaatt
    14281 acgctcataa gttcctccac ccttttaatg atagtctatg taagtatacc atatcagacc
    14341 cttattcacg gtcgtatact ggataaaaaa caaaaaaaca atccgcccaa cagaatatct
    14401 tatcccatca atcccacaga ttctattgag catctgtgtc tttgaggaat acctgttatc
    14461 tattgttcgg attgctttct atctactact tttttacagg aaatttacct attagttttc
    14521 tctgctgtaa tttttgactt ctgcttccat agcatcaata aagatattca aatcttctac
    14581 agctgtttct ttacttccat aacgacgtac gttcactgtt gcatcttcca attccttgtc
    14641 tccaacaact aattggtaag ggatcttttg tgtttgagag gcacgtatct tatagcccat
    14701 tttttcatta cgatcatcaa cttctacacg caaccccttc atttgcaaac gttctttgat
    14761 ttcataagca taatcgccat gtgcatcaac agaaacaggg atgattgttg cttgtatagg
    14821 tgccaaccat gttggaaaag cgcctttgta tacttctgtt aaataagcga caaaacgttc
    14881 cattgtagaa acaattccgc ggtggataac tactggacga tgcgtatttt ccccgtcttc
    14941 tccaacatat gtcaaatcaa agcgctctgg caataagaag tctaattgta tagttgataa
    15001 tgtttcttct gtaccaagag ctgttttgac ttgaacatct agttttggtc cgtaaaaggc
    15061 tgcctcgcct tctgcttcaa agtaatctag ttctaattca tccatagcgg ctttcagcat
    15121 tgcttgggct ttttcccaca ttgcgtcatc atcaaaatat ttatctgtat tgtttggatc
    15181 gcgatagctc aagcggaaac gataatctgt aatattgaag tcagcatata ctgccaccat
    15241 caattcaagc gtacgtttaa attcatcttt gatttgatca ggacgaacaa atgtatgacc
    15301 atcattcaac gtcatttctc gtacacgttg taaacctgac aaagcacctg atttttcata
    15361 gcgatgcatc attcctaatt cagcgatacg aattggtaat tcacgataag aatggatcgt
    15421 gtttttgtag accatcatgt gatgagggca gttcattggg cgaagaacaa gcatttcgcc
    15481 atctcccata tccattggcg ggaacatgtc ttcttgataa tgatcccagt gtccagatgt
    15541 tttgtacaac tcaacatctc ccattattgg tgtatataca tgttggtaac ctagactaac
    15601 ttctttgtct acgatataac gttcgatcgt gcgtcggatt gttgcccctt ttggaagcca
    15661 gaatggcaaa ccagaaccta cttctgggga aaccatgaac aagtcaagtt cttttcctag
    15721 tttacgatgg tctctttctt ttgcttcttc acggagacgg atatattctt tcaaagcttt
    15781 cttgtcaaaa aaggctgtcc cgtatacacg ttgcatcatt tgattgtttg agtttccacg
    15841 ccaataagca cctgccactg ataataattt aaatacttgt atacggccag tggatggaac
    15901 atgtggtcca cgacacaaat cgatgaattc gccttgttga taagcagtaa tcacttcttc
    15961 ttctggcaat tcactaatca gttctacttt gtacggatca cttgcaaaaa tttctaatgc
    16021 ttcctgtttt gaaagaacac ggcgttcgat cggcagattt tctttgacga ttttcatcat
    16081 ttctgcttcg attgccggca aatcttctgc agttacttgg ttttgtccat tatctgtatc
    16141 gtagtaaaac cctgaatcga tagctggtcc aacgccaaag tggatatttg gatagaggcg
    16201 acgcatggct tgggccatca aatgagctgc tgaatgacgg actaagccaa gtgcatcttc
    16261 atggtctggt gtgatgatct caatacttgc atcttcctcg attggacgag tcaaatcaac
    16321 gagttttccg ttcactttac cagctaaagc tttttttgct aagctttttg aaatgctttc
    16381 agcaattgcc aatgttgttg ttccagactc aaattctttg actgcaccat ctggaaaagt
    16441 aatttttatc ataatagttt cctccttgaa atgttttgat tgatcagatc atcaagctga
    16501 aaaacaaaaa aatcctagca tctcttgaaa agagatacta ggacgaaaag ttcgtggttc
    16561 cacctaatgt tcaaacgcaa atgcgttcct caagcgttgt aacggtccga ccgcccttgc
    16621 ttcaacaagg gtttcgaaag tggtcatcct ttggttttct cctggaaaag tttcagccta
    16681 gcttttcctc tcttatcgaa gactctcaaa ttcagttggc tttctcatca atcaattatg
    16741 tgtttattta accactaata aatagaaaaa tcaagtggga aactaaactt attttttcca
    16801 ttccccattt acaccgtatg ttcctttttt catctcattg atgatgacat ggatgtgttc
    16861 ttttggtgcc tgcgtgtttt tatgaacagc ttccgtgata tctttcatca tattttctaa
    16921 ttgttccgga ctgcgacctt ctactaattc gacatgtacg aatggcataa tgctctctcc
    16981 tctttctgat cgttcttttt tcaactcgat tctatcatac tatgtttgtc ttgggtactg
    17041 aatcaggaaa aatggctgga tctttttttg ctctcaaggc actcaaaata gagaccgtat
    17101 ccacgacttc ttgcaaaaca gctccgaata atgcggggat tagtcccgta cttgcaatta
    17161 acatcaaaaa aatacaaata aagatgccaa tcagtacaga ctgtttcgct attctcatcg
    17221 tatctcttga aatcactact gcttttgcta cacgcaagag atcatctttc aagatgaccg
    17281 catctgcact ttcactagca gctgtagaac catgagcccc cattgcaata ccgatatctg
    17341 cagcagcaag tgctggtgcg tcattcacgc cgtctcctac catcgcaaca ggtctttgat
    17401 ctttagggat actttctaaa atggtcagtt tatcttgagg caagctacgg gcatgtacag
    17461 aatctaattg gactttttct gcaatcgttt gagcaatggc agatccatcc ccggtgatca
    17521 tcatcaaatt tttcacatca agttttctta gctccttgat tgtctttgct gcttctgggc
    17581 gaatctgatc cgaaaatagg atcgttcctg caaaagatcg atcaattgtt acatagattg
    17641 ctgtattgga cgtttctatt tcttcagctg aaacaaaaga ggcacgtcca atctttactt
    17701 catgattatt gactactgct tggattcctt gaccggtcac ttctttcagt tgactaacag
    17761 gatacagttg gctgtttttc acgttgttca ctaacgaacg agctaagata tggctagatt
    17821 cctgttctgc actagctgca tacagaagta gctcttcttt ttttattcca ttgactggct
    17881 gaatcgcctc tacttccaat atccctttgg taagcgttcc tgttttatca aaagcaatcg
    17941 tttttgtacg tgcgagcttt tcaatcgttg ttccagtttt tacaacgatc ccgtttttac
    18001 ttgaacggct cattcctgca actaaagcaa tgggcgcagc tagaatcagt ggacaaggtg
    18061 atgccactac cagtacctca gcaaatcgta aagggtcttt tgagaaccac caagaaatac
    18121 caccgatcaa ataagcaatc aacgtgaaag ggactgcata acgatcagct aaacggacaa
    18181 atcgggcagg cttttctttt gattcttcga ctagtttaat aatcatttga tactggctgt
    18241 ctgcggcacg tttttcagcg atcatttgga tcgatccgtc tccatttaaa gaccctgaca
    18301 taatctgatc tccaggtttc ttggtttccg ggcgggactc acctgtcaaa gaagattcat
    18361 cgaccgaaga ttctcctttg gtcactcgac catctgcggg tacaagttcg ccaggtttga
    18421 ctagtaactg gtcatcaata tttatttcat cgattactat atcctgcaat tttccttctt
    18481 tgaatcgatg ggcaattctt ggggtgttat ctaacaaaga ctgcagttct ttacccgctc
    18541 gtttattcgc gtaatcctct agactatctc cgcccgtaag catgatcaat atcatcaaac
    18601 tagcccagta ttctttgacg gctaatgttg caaggattgc ggtaatcgct aatacatcta
    18661 cgccatatct tcctgaacgt aacgtcttga tcatttccaa aaacatcaag aaggcgagaa
    18721 tccctccagt aaatgcgaca atcgcaaatg caagggccgg ctggtgaaaa acaaattcac
    18781 ttaataaagc tatcccacca ataagcaaag taagtaaaaa ttttttgaaa tgtgtcattg
    18841 ttttttctcc tcttttatgt gacttagaga ggttagtaat aaatttccag ctgcctcttt
    18901 catcttaagc atagtccttg actagcactt tttaaaacaa taggccttaa ttgaaaacaa
    18961 ctatcactat cagcgtttcc aaaattcatc agttctacaa acaaaaatat tcagcaagga
    19021 ttactttttc gattcatcag ttaaaaagta ccttttttcg aaaaactatg ctatactttt
    19081 aattcgttat ttacggcgga aggagcaaac atgcgatgaa tgagaaacaa ctagaacaaa
    19141 cgcacgtgga tgaaacgatc gaactaatcc agatcgaaca aaatatgctg gatacaaaac
    19201 aacaagaatt gactcaggaa atgaatcatt cgacaaaaga cacagctaat cacaagattc
    19261 gagctggttc caatgaagct ttttatgaat ctgctgttga atatcgccaa catgagcagg
    19321 aattgctttt gaaataccat actcttgaag cacagcaaaa acgcctgcaa acgttgtctg
    19381 tcatgaaaga tagtccttat tttgcccgta tcgactttaa agaagaccgt gaaacagaaa
    19441 cattatatct aggtatcgct tctttaagag atctggcaga agaaacaatc gttattgact
    19501 ggcgcgcacc aattgccaat ctttattatg aaggtgagat tggtcccgca ttttatgaaa
    19561 ctgaaacaga tagaatagat gtcgatctgc agttgaaacg acaatttaaa atccaagaag
    19621 gacgtatttt atctatggta gatacgtcgg aagtaatcaa tgatgacttt ttgctagaga
    19681 tattggatga atcatcaagc aaccatatga aaaacatcgt ctctacgata caaaaagcac
    19741 aaaatgcaat cattcgggac acaacaagta aagtaatgct gattgaagga atcgccggaa
    19801 gtggaaagac atccgctttg cttcaacgta ttgcttttct gttgtatcat aatcgcaagt
    19861 ggctcgaggc tgaaaacgtt cttctatttt cacccaacca tttgttttct gattacatct
    19921 cgactgtatt gccttcatta ggtgaaagcg gcgtgcctac acagacattc aaaaattatt
    19981 tggtgcagct gctgccagag ttttctttac tagatgaaca gcaacaagaa agtggttttt
    20041 tgctagggga aaaagatccg atacaagtga tgaaaagcgg attgacctta gtcgatcaga
    20101 ttgatcgcta tatccaaggc atcacaaact acggtccctt gttccgtgat atgaaaataa
    20161 atggccgtac gatcctatca aaggaatcga ttcgccaatg gtataaagaa acaaatgaac
    20221 aattaccttt acatcataga ctttctctat tacaaacgaa gctcctgaaa aaattaggcg
    20281 gtctgcaaaa agacgaaaca cgtcagcaat gggtcaaaga tctggcggaa gaacagctcc
    20341 aagaactata cgcaacagat ccaaatcttg aatatacaga acaaaaggag cgttcattac
    20401 gtaaaaaact ggccaaccaa atcgtacgta aaagattccg tcgaatccat cgagggatca
    20461 tgaattatca atttgtcaat ataacgaaac aatatctcca ctttctacaa actgtgccac
    20521 tttctcttct aacacgacat aaaatcagcg agaccaggtg gcaggaacat ttgacaactg
    20581 ttcgtacaca cttgcgtcaa agagaattgc gtcaagagga tgctgtacta ttctttttac
    20641 tgatgcgccg aacatatcca gtgacggtta cacacaaagc tcgctatatc tttattgatg
    20701 aaatgcagga tttcgcacca tcacaagtgg cattgctgca agccttgttc ccaaaagcaa
    20761 atttgacttt ctgtggagat ctaaatcaaa atgtctttgg aaatgaaacg atcgttggat
    20821 cattggaaga ccttttcgtg gaccgtgaag tcactcgttt ccaattaacg acaagctatc
    20881 gctccacaaa agaaatcact gattttgcta atcattttat tgtgaaagaa catcaagtag
    20941 aaacaacagc aagaaaagga gaccttcctt tgctcatcca aggaacaaca gatgatatca
    21001 aattgaattg gttagcagat accattcgaa cgactcaggg aaaagcccgg tattggcgta
    21061 cagcaatcat agctaaaaca caagaagaat gcgaagctct ttatgctcaa ctgccagacg
    21121 agttgaaaca acaagtccag ctgattttaa atgagagtga ctttatgaag cgttccatta
    21181 ttttacttcc agccttttta gcaaaaggtc tggagtttga ccgagttttc ttgtgggatg
    21241 tagatgcaga acatttttct tctcagcaag acaaattgat cctttacacc atgtgtacac
    21301 gtgcgatgca tgaattgacc ctttttacct ccaataatga aagtcctttg ttaaacaata
    21361 tggatatttc atcttatgag aaaaaagtac tgtaagtaaa aagacaactg ctatcattaa
    21421 tgttagcagt tgtcttttta tttacaataa taattgcaga aaaagtaatt caatcattta
    21481 aggtcattta ttctatatat aaatccaaat ctgtttcagg atattttaat ttgacaagcg
    21541 aaataatcat tttcagttct tccatgtttt ctggatattc tgggtcaaat accttgctat
    21601 gacggccaat cccgccattg tcgatcaatc ggtaaattcg attccattca atgaattggt
    21661 caattgattg gaaattgctg attggatagc cgccacaatc caaaatctct gatacacgaa
    21721 atgctaggta tgcactatcg atcactttat tttttttcgt gtctatcttc tcatttcttt
    21781 cgataagaat tttttcagga cgatgtttca agctccactc taatagtaga aagaaagcct
    21841 ccatccgata ctcttcttca aataaccgaa aggctgaatc agaacgacga aaaagcagcg
    21901 gaatcagata attttgtcta taaatcagca ttggtgcgcg gtccaccata cactctaaat
    21961 aacggttcag ataccctgta ccgacatagt ttcctaatcg atagccttca acgccgaatc
    22021 ttgcgtattt ttgcgctaat tttgaacaat cagttacgtt cacagctaac tcttctactt
    22081 tgcggtaacc gcttaagata cgttcaaaag gttctaaagt gatttttgct tccatattct
    22141 tccccgtcca tcttccacat acttcatatc atttcacatg atacttatgc tctcatcata
    22201 ccacaggttg aattagaaaa gaaaataaat cacacaaaaa agcaagacaa tctgttagtg
    22261 agattgtctt gcttttcgaa aaagactgaa tacttttcgt taaaactggt tgcttagtct
    22321 tctaatgcca cattatggaa cacatgctgt acatcttcta gatcttccag tgcatcaatc
    22381 attttttcaa atgtttcttg atcttctgga gatagtgtta cctcgttttg agggatcatt
    22441 tggatctcag cgattgaaaa atcagtgatt cctttttctt ttaatgcttc ttgtatacta
    22501 tggaaatccg ctacttcacc gtaaacgatg atttgtcctt cttcttccat tacatcgcga
    22561 acatcgatgt ctttttccat taggtattca aggatctcgt cagcgtcttc tcctgcaaaa
    22621 gcaaagattg ctgtattgtc aaacatgtaa gaaaccgctc cggaaacacc catgttcccg
    22681 ccatttttcc caaatgctgc ccgtacgtct gctgctgttc gattcacatt gttcgtcaat
    22741 gtatcaacaa tcaccattga gccgcttggt ccaaatcctt catagcgcaa ttcagagtat
    22801 gtttcatctc ctgcaccttt tgctttttcg attgctcggt caataatatg ttttggtaca
    22861 ttataagttt tagcgcgatc aatgacgaaa cgtagttttt ggtttgcatg cggatcagga
    22921 tcacctgatt ttgctgccgc gtagatttca atcccaaatt ttgcataaat ccggctatta
    22981 ttagcatctt tagcagtttt ctttgctacg atatttgccc atttacgtcc catattttca
    23041 cttcgctttc tgatttgata gtttcataac gcaaaaacgt cctgttccat tatacttgtg
    23101 aatcacgatt ctgtgaagct ttttttcttt cttccttcat tcttctcatt tttagtcaat
    23161 tatctatact cggattggga tttgcccgaa attctgttcc ggaatattgc ctcccaattg
    23221 atagatttga tcacttctaa ctaacagttc cgcttcttgt gcctcttttt ttccgattcg
    23281 ggaataaata gaaatctctt ttttttcttt taagaatctt cttccagcat cggtaaatcc
    23341 aagtagtcga agataatttt tattttgttg gacaggaatc tcttgctttt tgatattcag
    23401 caagacataa caagataatc gttggatccg tgtccatgta tatctttttg tttttacctt
    23461 tgacacaaaa tcctcaaaac tatcagcagt tgcagctgct gttttcatgc gcgattctat
    23521 tccttcggtc atctgataga tatctgtcag ttccagcaaa gtagaagata acaaccgata
    23581 acgcaaatac ggccaataag attcccaagt ctgcagcgaa caagttgaaa gatcttcttc
    23641 tgtctgaggc ggcacaagtc cagctattct ttttccttct tctaacgcat ggcgaatggc
    23701 tgttgcactg gctatcctct gatctgtgat gattttttca tgatagcctg cacttttacg
    23761 tcggatcgga tgtaattcca tagggtggac atacttggca ttttcctttg cataacttaa
    23821 tcccaagata tgatttggcg aagaaaaatc aagcgtaata tcgggataca gactgcgaaa
    23881 aacctcagtc attttttgcg gataactata cgtttgatca gacagttctt gaaatgcctc
    23941 ttctatccta tcttgattct cttggacaaa gcgtccgaaa ctgctgtaat caaacgaagt
    24001 ctcttcttct gttccaaaac acaaactgtc acagtccagt gtttgcaaga tttttactgc
    24061 acctttagca aaatagtcag ctgactgaac cgcccattcg acgggaagct ccactactaa
    24121 atccacacca ttttgtaaag cttcattcgc gcgatgccat ttatcgatga tagccggttc
    24181 gcctctttgc aaaaaattcc cgctcattac agcaatgacg acctctgctc ctgttatttt
    24241 tcgtgccatt tccacatgat agcgatgtcc attgtgaaaa ggattgtact ctacgataat
    24301 cccgcagctt ttcatgcgca tcctccttca tagttatcga taaaaaagaa atagagacaa
    24361 gtaaaaaaag gcaaaaatcg gaaaaaatac ccgaactata taaactattc tcgcaaacac
    24421 aatacttctg cgacgaaaag ctgcactgca agagcaatgc ctatatcgtt cggatatata
    24481 atttatgttg aagatttatt cttttcttgt taactcgagc aggcaaaacc gctagtcttt
    24541 gtatgctaca aagaaccagc gctttgattt ctctgatgct gcttcgtctg taaaatcaga
    24601 aaatgcttcg actttcgaaa agccgctgtt ttccagcatt cttaaataac tttccaatgg
    24661 ataggtacgc tcttgatgta gttcatcttc acgaataaat cgaccagacc cttcttgttc
    24721 ttcaacgaaa aaggtaagaa aatgttcgat gctgtgtttc tcgcttcctg gataactatc
    24781 ccacaaaaaa gcaaaattat ccccttgata atgatagcta tattctggaa aaacctcatc
    24841 tacttgatag gtggagtgta cgtcaaataa aaatcggcca ttttcttcta acgcttgata
    24901 gacttcatca aacacttgct gtacctcttg tctatttttc atatagcaca gcgaatcaga
    24961 aaaacaggta attgcctgat attgtccgat ttctgataaa tcgagcatat tgccttccac
    25021 aaattggatc gatgcgtctt cttcatatgc tcgctggctg gcaatcatca acatctcttc
    25081 tgaaaggtct aaccctgtca ctttatatcc atcttttgca aaggcaaccg ctaatgctcc
    25141 agtaccgcat gccagttcca aaatattttt tgtgtcttct tgtaaatgac gtttcgaaaa
    25201 agctaaccat tgctgataaa gtgtttcgtc catcacttca tcgtaaatga aagcaaatgt
    25261 ttcataagcc atatgttaat ccaaccattc actaagatcg actagcggag catctgacca
    25321 tagtttttcc agattataga aatttcgttc tggcgcatgg aaaacatgta cgatcacatc
    25381 tccaagatcg atcaataccc attttccgcc ttcttttcct tcaatacgtt ttacttcata
    25441 tttgttttct tcttctttat caatgatttc ttctgtaatt gcgttgattt gacgttcgct
    25501 atttgctgaa cagatcatga aataatctgc caacaaggaa acatttcgaa cgtctaaagc
    25561 gataatgtct tctgcccgtt ttgaatctgc tgcttcaatc gcaattttta attgttcttt
    25621 actatctatg atgatttcct cctaatatga gcagcttatt tttttgctac ccagtaatta
    25681 tatgtttcga ttgtttttgg ataaatctgt tgttcttgcg caagcaaatg ggccaatgta
    25741 tgttttgttt caaatgctac agcttcgtct agatcagccc atgcaatggc tcgtgcatct
    25801 tgtaccccag gaaaatctcg acctggttca atatagtctg ctacataaat gattttgtca
    25861 aggagactca tcttagcagc cccagtcgta tgcacccgga ttgcatgaag aatctctgca
    25921 tcggtgattc ctaattcccg ctctacaaac gaagcgccaa caagaccatg ccagattgca
    25981 ttattataat tcaataactc cggatcaaaa ccgtctctta cgattaccat tttgaactcc
    26041 tcatctggtc gttcttttgc ataatcatgt gtcaatgcag caatactagc tttttcagga
    26101 gaagcaccgt attttttggc aagagccacg gctgtttctt ctactccaag cacatgcttg
    26161 aagcgttgtt cgctcattct catctgtatt ttttgcatca ggttttctct agaataagca
    26221 gtatattcat tactatagtc catattcata caacccttca ttttgaatat aatcaattac
    26281 tttatctgga acaaggtagc ggatagaaca gccttctttg atcttttgac gtattttcgt
    26341 ggaactgatg tcgatctcag gtacatctac ccaaattaca ggatatggag tatccgttgt
    26401 gtatcctggt cgacgtatac ccacaaagtt gaccatagaa gtcagctcat cgattttata
    26461 ccattttggc aaatattcta ccatatcccc accgataata aagtaataat ctgtatccgg
    26521 attgttttgc gtcaattcct tcatagtatc ataggtgtaa cttttcccac cacgagctaa
    26581 ttcaatcgtt tcaatctgca aaaaaggatt gtcttccacc gctaattcca acatgttgag
    26641 tcgatgtttt gcatcaatcg tctgtttctc atcaacatga ggtggctgat aagaaggcat
    26701 caaaaatacg cggtcaagac ctaaattccg gccagcttgt tcagccatca ctaaatgtgc
    26761 aaggtgaacg ggattgaatg ttccgcccaa gatccctact tgctttttct tctctaagaa
    26821 ttgaggcatt tcttcaggaa ataattgtga acgaacaaat gtcttagctt gcgtattcat
    26881 catggtcact ccttatattg cttttacttc ttttgatagc ctttgatact tttcttttgt
    26941 ggaaggtttg tataatacaa taacacgtcc aatgatttgg acgatttcgc aatctatttc
    27001 tttttctaat acttgagctg cttcttctgc aatctcatct gtattttgaa gtaacgatac
    27061 tttgatcagt tctctttttt ctaaagcttc ttcaatttga acgatcattg ctgaattgat
    27121 cccacctttt ccgatttgaa aaatcggctg aagatgatgc gctttgctac gtaaaaaacg
    27181 cttttgtttt cctcttaaac tcataatttt ccttcttcct taaatcaatg ctttgcgttt
    27241 caatacatct acaccctttg gcgcccagcc cgcaattact actggcgctg ttacagtgat
    27301 ccagcctaga ccggcaaaaa cgatgtctgt tttttctttc acagaaaact caaaacgaac
    27361 aagctccgga aatgccccga cttcatcagg acgaggaggc tgtaataatc cacctacatg
    27421 tttttgataa aattcgtctg ctttttccag tttcgttcga tgaatattta catcatttga
    27481 cacataagca ataaatgaag cacgattgcc gctgataaaa tcaaatcttg caagtccgcc
    27541 caagaaaagt gtttgccctt cattcagctg ataaacttta ggtttgattt cttttaacgg
    27601 tgcaatgatc cgcaaatctt ttttacctaa gtagtgcgcc atttgatggc gatggataat
    27661 tcccggtgta tcaatcaaaa aatgcccgtc atctaaagga atctcgattt tatccaaggt
    27721 cgttcctgga aactgcgaag ttgtgattac atcttgtact cccgctgtat ttttgatgat
    27781 ttgattgata agcgtcgatt ttccgacatt tgttactccg acgatataga catcccgtcc
    27841 atcgcggtat tcttcgattt tttctaatag ttccgtcatc tcatgagatt tcttagcact
    27901 agttaataat acatctactg gacgaattcc tgcttcgtaa gcacgttcct tcatccattg
    27961 tgttaattta gtttttttca atgatttagg taatatatcc actttgttcc caactaaaag
    28021 tactggattg tcaccgacaa aacggtgtag tcctgggatt agtgaaccat tgaagtcaaa
    28081 aatatccacc acattgacga tcaatgcatc tttttgccct aattcattca gtaagcgcaa
    28141 aaagtcgtca tccgtcaatg agacatcttg ggtctcatta taatggcgta atctgaaaca
    28201 acgctgacaa tagacttccc cggaagctaa acctttttcc aaagccgttt gcggcgtgta
    28261 tcctaattca ccgggtttgt ttgtttgtat aacggcacca cagccgatac attgtaattc
    28321 ttctgtcatt cgattccacc tcgccagccc atatcagggt gttttgctaa tagataggcc
    28381 ataattcttt tttcccaaaa acgattaaat tgtgtcttcc aactatctgt tgcgataatg
    28441 ggttttacaa ggatgctacg tatccctgca cgattggctc cacgtatatc agtcataatc
    28501 tgatcgccta ccattactat ctcatcatct gctaaatcca attgtttctt tgctatgttg
    28561 atccctcttg ctaaaggttt cattgctcgt gcaacataca aaagatcaaa tttttcaatc
    28621 gctcgcgcga cacgttttga attattgttt gaaacaacaa caacagggat tcctgcattt
    28681 ttcatttcta aaatccaagt aagcaactct tctgttccat ctggattatt ccatgcaatc
    28741 aacgtattgt ctaaatcggt caatactgct ttgatgccta gattctttaa ttgggcaggt
    28801 gtaatctgat agatggcttc taccatccat gttggtttgt aatttgaaaa catgctgtct
    28861 cctcatctgc aaaaaatgaa ggagcacata aagtactcct caaccccgta ttatactgca
    28921 tatcagcaaa aaaaactacc tctatactcg ttcgtctttc agaaaaagca tttctttaca
    28981 aaatgaccaa aaataaagat tgatcacaga aaaatttaga aacaaaaaac aactaatatt
    29041 ggcggaacct cttgtatcgt ttttccagta atttatgctg atctaatcga acaagttccg
    29101 tcaatctttc aatcaacgct tttttcataa tgtgtgcgac tttatatcgt ggcaactgct
    29161 cgccgttgaa cgtttcagga ataactcgat caacgattcc taactcgcgt agttctggcg
    29221 cagtaatttt catcaactca gctgcttctg cggcgcgact accgtctttc cacaaaatcg
    29281 acgcaaatcc ttctggagaa agcacagcat aaatcgtttc ttccagcatc cagacttcat
    29341 ccgctaaacc tagagcaagg gcaccgccac ttccaccttc accaatgatg atggcgatga
    29401 tcggtacctt taaatcagac atttcgagca gatttctggc aatagcctct ccttcgccgc
    29461 gctcttctgc tcctacaccg caatatgcac ctgctgtatt gatcaaggta atcaccggtc
    29521 tattgaactt ttccgcttgt ttcatcagtc gtaaagcttt tcgatagcct tcaggatggg
    29581 gagaaccaaa atttctgcgg atattttcct gcagatcccg tcctttttga ataccgatca
    29641 ctgttaccgg tttgccatct aatcgagcga ttccaccaac aatcgcttcg tcatctgcaa
    29701 ataaacgatc accatggcat tcctcgaaag aatcgaagat ctcttcaaaa aaatccaagc
    29761 ttgtccatcg ttctttagct cttgctaact gaacgacatc atgtgctgtc ttatccacga
    29821 tctatccatc ctttctgtgt atgcaattca agaagcgtat ggattttctg tttcaattcc
    29881 atgcggggaa caatctgatc gacaaaacca tgagataata agaattcagc cttttggaaa
    29941 tcttctggaa gttcctgctt gatcgtctgt tcgatgacgc gtcttccagc aaaaccgatc
    30001 aagctttggg gttctgctag aataatatcg ccttccattg caaaactggc agttactcct
    30061 ccggtcgtcg ggtccgttaa aacagttaga taaaaaagac cttcattgct atgccgtttg
    30121 acagcagcag agatttttgc catctgcatt agagaaaaga ttccttcttg catccgtgcg
    30181 ccacctgaag ctgtgaacaa gacgactgga agactttcct ttgttgctcg ttcgaataat
    30241 ctggtgatct tttctccgac aatcgttccc atacttccca tgataaaatt aggatccatc
    30301 actccaataa tgaagggaat cccctgaatg gttgctttac cagtgaggac tgcttcatga
    30361 agtcctgttt tatcttgcat ttttttaatt ttttccgtat attcgggaaa tgctagcgga
    30421 tctttggtta caagatccgt atcccattct tcaaaacttt tttcatcaat aatcaaagct
    30481 agacgctgcc atgcaccgat tcgaaaagcg tatccgcaat gagggcatac tttttcttca
    30541 ccgatgtctt tcgtataaag gatatgtttg caatttggac actttgccca catgttatca
    30601 ggaacagatg gcgagttagc aggtttgctc tctctattag gattgatccg aatatatttc
    30661 tttttcttaa acagagccat ctatgcgcct cctatctccg tttctggtgt ccaattcggt
    30721 aaaaattctt cttgtaaaaa tgctgtgctg taatcacctg ctatgactgc aggatgacta
    30781 atcaaatcca tctgaaattc tgcgttcgtg atgattcctt ctgtgataaa ttcacttaag
    30841 gctcgctgca tcttcattaa tgcttcaaaa cgcgtatttc catggacgat tatttttgca
    30901 atcattgaat cataatatgg cgggatcgta tatcccgggt aaactgcact gtctactcgc
    30961 agtcccatcc cacctgctgg aagcagtaag ttttggatct tccctggaga aggagcaaaa
    31021 tggaaagcag gattttctgc attaatccgg cattcgattg cgtgtccttg gaatactact
    31081 tcttcttgac acacattcaa aggctcaccg gctgctatct ccacctgttt ttttactaaa
    31141 tcgattcctg tgaccatttc tgttactgga tgttccactt ggattcgagt attcatttcc
    31201 atgaaataaa aatcgccttc ttcatccatc agaaactcga tcgttccggc attttcataa
    31261 ttgactgctt tagctgctcg aacagcagcg tctcctagtg cttctctttt tgtttgtgag
    31321 atcactacag aaggagattc ttccagtact ttttgattgt tgcgttgtaa agaacaatct
    31381 cgctcgccta aatgaatgac atgaccaaat cgatcaccta agatctgaac ttctatatgg
    31441 cgagcaggat aaatgatttt ttccaaatac atatcatcat ttccaaatgc cgctgctgct
    31501 tcttgctgag ctgaagaaaa atgctgtggg agctcttctt ttgattgaac tttccgaatg
    31561 cctttcccgc caccacctgc agctgctttc agcatcactg gataaccaat tctgtctgct
    31621 atttccaatg cttcttctac tgtagataat acaccagtac ttcctggaat gactgggaca
    31681 tttgcttctt gcatcaattg acgcgcattg atcttatttc ccattgcatc gatcgttgca
    31741 cttttaggac caataaatgt gatattgcac tcttcacaca tggaggcaaa tcggctattt
    31801 tcagataaaa aaccaaatcc tggatgaatt gcttcggctt ttgtcacgat tgcagcgctc
    31861 agtacttcct gaacattcag atatgaatca acggcttttg ccgggccaat gcagattgct
    31921 tcatctgcta actgtgtatg aagtgcttcg gcatctgctt ctgaatatat cgctacggtt
    31981 tggatcccta gttcgcggca tgcacgaatg atacgtacag cgatttcacc gcggttagct
    32041 atcaatactt tagaaaacat atttcaccta tccaatcata aaggttaatt ccgcttcggc
    32101 tactttttta ccgtctactt tagcgattcc tttgcctatt ccggctgaag ctttcacttt
    32161 caatatctca acttcaaggt ataaggtatc tcccggtgta actttcttac ggaattttgc
    32221 tttgtccaat ccgccgaaat aagccgtctt tcccttgaat tgttcaagag aaagtaatgc
    32281 aactgctcct gcttgagcca ttgcttcaac aatcaatacc cctggcataa caggttcttc
    32341 tggaaaatgt ccttgaaaaa agggctcatt gatcgttaca tttttcttag caacgatccg
    32401 ttctccttca accatttctt ccactcgatc aatcaaaagc attggataac gatgtggaat
    32461 gatttctttt atttcttgta tgttcattgt tttccctctt tcctgctttg cttatttttg
    32521 ctgaatccta aagagtggct gtccatattc gacaactgac tcgttttcta caaggatttc
    32581 tgtgatcact ccgtcggcct cactagttat ctcattcatc agtttcatcg cttcaataat
    32641 gcagataact tctcctttgg caacttgatc acctactttt ttgaaagctg gtttgtcggg
    32701 cgctggttgc agataaacga ttcccacgat tggcgaaaca acctcgattc catcaaatac
    32761 tgccgattct ttttctttca ttatttctgg agcagttgtt gcttgttcag gtatgacatt
    32821 gactggctcc gaaactggca acgtttcgtt tgtttgaacc atattcatgc ctcgacttgt
    32881 tttattttta ttcatataca attcaaattg accttcacgc aaatcgaatt ccgttagcga
    32941 ggattgatca aattgactga ctaattctct gatttcattg atatccaaaa ttattcctcc
    33001 cagcgtttca tgcacagaac cgcattatgt ccgccaaacc ctaatgaatt actcattgca
    33061 taagtaaaac ttgcaggttt gctttcgttt ttgacaactg tcaagtcaat ctcaggatct
    33121 tgtttttcta cattgatcgt aggtgggata aattgatgtt ctaatgccag caaagttgcc
    33181 aaggcttcga tcccgccggc tgctcccaat aaatgtccag tcatcgattt cgtgctgctg
    33241 acgtaagtat ctctgaaatt ttcacctaat gcgatttgga ttgcttttgc ttctgcctgg
    33301 tcattggctg gtgtacttgt tccgtgagca ttgatatatc cgacttgttc cggctgtaca
    33361 ccagcttctt ccatcgcaag cttcattgct ttagatgcac cagaaccatc tggagtagga
    33421 gctgtcatat ggtaagcgtc acagtttgca ccgtatccaa cgatttctcc atagattttg
    33481 gcaccgcgag cttgtgcatg ttctaaagat tcaagaacta gaacgcctgc tccttcaccc
    33541 atcacaaaac cattccgatt ttcgtcaaac ggaatcgaac cacgattagg atcagttgat
    33601 tctgagagtg ctgttaaagc tgcaaatcca gcaatcccca tctcacaaat cgttgcttct
    33661 gttcctccag caagaatgac atcagaatag ccatgtttga tgttacggaa tgcttcccca
    33721 attgaattcg ttccgctagc acaagctgtt acgatagctg tacaaatacc ttttgcacct
    33781 acacgcaaag caatatttcc agctgccatg ttggcaatcg ccattggtac gaacattgga
    33841 gaaactcgtt ttgcaccttt ttcatgtaga cgaataactt ggttttcgat tgttggaaga
    33901 ccaccgatcc cagatccgat gatgacgcca aaccggtctt gattcatttt ttctttatct
    33961 aaaccgctca tctccattgc ttctaaagca gcgtagattc catagatcga aaacatatcc
    34021 attcgtttgc tatctttttt aataaaatat ttatcgtaag ggaaatcttt gacttcaccc
    34081 gctaaggtaa tccctgtttc tgaagcatca aatttagtga tcggtgcgat gccattcgtc
    34141 ccctctttta agctattcaa aaagctgtct gcgtcatttc caataggtga agtgactcca
    34201 tagccagtaa ttaccactcg attcatttgt ttgctctcct tttcttatcc gtgcatgacc
    34261 aatccgccat cgacattgat gacttgtccg gtgatatatg gattttgtgc taagaaaact
    34321 gctgtttgtg caatatcttc tacttgtccg aaacgctgca tcggaatttg cttttccgct
    34381 tgttccttga ctttgtctgc taaaacttcc gtcatatcag ttgtgatgaa tcctggcgca
    34441 atggcattac atgtaatgcc tctagttgca gcttctcgtg ccacagattt tgttaatcct
    34501 actacgccag ctttactagc tgcataattt gcttgaccaa tatttccaat caacccagat
    34561 acactagaga gattaatgat ggccccttct cgctgcttca tcattttttt caatacgtgc
    34621 tgcgtcatat tgaaggttcc aatcaaattg atatccagac attttttgaa atcttctgca
    34681 tccattcgca tcacaagttt gtcatttgtg attccggcat tgtttactaa cacatggatc
    34741 gatccaagct tttcttctgc ttctttgatc atttgtcccg ctttctcata atcagagatg
    34801 tcaccggaaa ctcctacgca ttttacaccg aatgcttcga tttcttctat cttttctttt
    34861 ggaatctctc cgcgaccatt caaaatgata tttgctccag cttttgcaaa agctaaggcc
    34921 atcgctttgc cgattcctct tgtactacct gtgataaata cattttttcc ttttacatcc
    34981 ataacgttcc tccttatagt attgctattg tttcatcaaa tgtctgctta ttctcaacac
    35041 gcagaactgg tattgtttta tcgatttttt tcataaatcc gcttaatact tttccggggc
    35101 cgacttcgat gacttgttcg atgccgattg tttttaactt atggatactc tcatagaaac
    35161 gaacaggttg catgacttgc tgttcaagta gtcccgcgat tgtttctttc ttcattattt
    35221 ccgttgttgt gttgcttatg ataggaaaag aaggttcaga gaattgaatc tgacttaggt
    35281 ccttcgccag tttttttgct gccggttcta aaatagctgt atgaaaaggc ccgctgacat
    35341 ttagagggat cattcttttg aacccttttt cttttaatag taaaacagct tcgtctactg
    35401 ctttttcttc gccaccaatc acgatctgct gaggtgtatt ataatttgca ggagatacga
    35461 tgccgtactt gctagcttca tgacagcttt cctcgatcgt ttcaatcggc gcattcatca
    35521 ctgcaaccat tttcccgctt ccagctgggg cagcttctgt catataagcg cctctttttg
    35581 ctactaacgc aactgcttca gtgaaggata gcgcattact agctactaat gccgaatatt
    35641 ctcctaaact cagtcctaaa gctgcatctg ggatgattcc atgctccttc aataagcgat
    35701 aatacgcgat gctgactgtt agaatagctg gctgtgtata ttgcgtctga tccaaacgtt
    35761 cattttctgt aaagcaaagt tcagccatat cgtagccgag aatctcactt gcttcatcaa
    35821 atgtctgctt tacaacggct tcttcatata aatcttttcc cataccttga tattgtgcac
    35881 cttggccact aaataagaat gctgttttca tgtttttctc caatatatcc agaatatatg
    35941 tttgattctt cctattcaaa aaggccgaga cattcctatt tcaggaaatg tcccagcccc
    36001 caacctaatt ttaatgatta tgcagtttgt ttttctacgt aagtcactaa atcttgaacc
    36061 gttttgattc cgtcttctgt ttcgattttc acgtcaaatt catcttcaat ttcattgatg
    36121 atttggaata aatccaagct gtcagcttct aagtcttctt ggatgtcagt agtcaatttg
    36181 atttcttcag tttcttttcc taattcttct gcgatgattt cttgaatttt ttcgaatacc
    36241 ataataatat attcctccga tattgtttgc tttttatttt tataatttaa cagtctacaa
    36301 ctccatgaga atacttcccc atgttaaacc tccgccatag cctgtaaata ttactttctg
    36361 ctgttttcct aaggtgatct ttccactaga aactgcttca tccaataaga tagggatgct
    36421 tgcagcagat gtattcccat atttatccat attggtcagg aacttttctt gcggcatctt
    36481 tacttttcgg gcaattttct caataattct gaggtttgcc tgatgcaaaa gcagataatc
    36541 aactggtttg tctttcatga cttcttggat attgtttgca acgtctcgta cggcaaaatc
    36601 aaaaatatct ctgccagtca tttgcaaata atacgaacct tctgaatctt ctgaatagaa
    36661 cggattttta ttttgctggt agccagcggt caatgagcta cttctggtac cgtcagctgc
    36721 taatttttct ttcagcaatt ttttctgtgg attcgcttct aagagaatcc cacctgctcc
    36781 atcgccaaac aacacagcag tcgtacgatc agaccaatcg attagcttag atagtgtttc
    36841 accaccaatc accagtccct tagttgagcc gcagcggatc attttttcag ccatgcttaa
    36901 cgcataaaca aatcctgagc acgcagcact gatatcaaaa gcgatagcat gagttgctcc
    36961 caatttccct tgtacttgtg ctgctacaga tggtgtcgtg taatcgggcg acattgttgc
    37021 tactaaaata aaatccaaat ctttagggtt tagatttttc tgttttatca atttttccgc
    37081 cactaaaatg cataaatcag aagtctcctg atttgttaca catcttcgtt cacgaatacc
    37141 cgtccttgac gaaatccatt catcagaggt atccatcatc ttggaaagat cattattagt
    37201 aataatcttt tcaggaagga cgctggctgt tgcagtaatc attccaaatt gttccattaa
    37261 atatcctcac ttatagtctt gcaagaagtc gtgcaagttt ttcagtgcat ccagcaaggc
    37321 atgctgttcc tccgtagcca ttccgtctaa gatgttcttg accatttcac gatgaaaatg
    37381 ctgatggacc cgaaatagta actttccttt tttcgttagt cccaacttta caacgcggcg
    37441 gtcatcttca ctgcggatac gttcgacata gccttttttt actaacttgt taatagcagt
    37501 ggtcaaggtc ccaacagtaa ttgatagttc tttggctact tctgaagttg tttttttctt
    37561 gtacatcccg attgcctcga tcgtgtgcat ctctgtgatt gacagatctt tgaattgaga
    37621 ttttttcagc tcagactctt cgattgtcaa aatatcattg aagacactaa caagataatc
    37681 atttactgtt tttaaatctg gttccatgtt ccaccgtcca ctaattagtt tgattatcaa
    37741 atcttttgat gttcaaacta tatcttaact tttttcaaaa tgcaacctta aaagatcatt
    37801 tttttactat atgagctttt tttaagattt tactcattta aaacaactga taaatcagca
    37861 tttataattt cttttattag aaaaatcatc tatctcacat attttgatta tcaaagtatt
    37921 ttctgtgaac agaactatag aattccctaa aacttgtcca ttatttcaaa atttgttata
    37981 gtctttttat tcaaagcgta aaaggagatc ctatgttaaa agaaaaaatg aaaactctcc
    38041 ccatgctgcc gggtgtctat cttatgaaag accgagatgg taaggtcatc tatgttggta
    38101 aagcaaaacg gctcaaaaat agagtaagca gctattttca tcagaataaa cagcattcaa
    38161 aaaaagtatt acgtatgatt catcatataa cagattttga tttcgtcgta gtagacacgg
    38221 aattagatgc tttattgctc gagtgtcaat tgatccaaca ttaccgtcct ttttataacc
    38281 gacaaatgaa ttatttcagt aattataatt atgtacatat taccaataag ggatttgtat
    38341 taacagatac tcctacggct cgaacatacg ggccttttcg tctctataaa aaaatgccgt
    38401 ctattttgcg tataatggaa gaaacttatc aaatgccttg gttgtctgaa attagtttgt
    38461 tagctttgcg agtccagctt cctgacctac aggaaatgac ttttgaacag aaaaaaaagg
    38521 aactccaagg gctgtttcaa ggccgaaata aaaagctact gacttacttg aaaaaaagac
    38581 aacaacattt catctatcag ttgaatttcg aaaaagccgg tatgcttcaa aaagatatcg
    38641 aattagttac ttattttatt agacggatcc aggaacaaaa gcagttttta agaacaccat
    38701 cgctcacctt cagcatgcca ttagcagcag atgagagtca gaaaaagcac tacctcgttt
    38761 gttatggtca acttgcagaa acaatgatta cctctggtga cgtttctcct gacttctatt
    38821 atgaaaagaa agaagctcat ttatctttga aacgtcaatt gtcaaaagaa gaaatcgatc
    38881 ctgtacaaat cttgatcagt taccgcaaaa aattagaaaa agaacagttt gaaattgaac
    38941 tgttaaacaa aaaagaagct gaaaagcaac taaattagtt gcttctcggc ttcttttagg
    39001 catcttcaac ttcaaatgtc aattatccta aaatttattg gattaagtca tagatttcca
    39061 tcgctacgat atcgatatta tcaaattcgt attgctgatg agtatctgtt tcagttaatt
    39121 caaatgtatc ggtcgcttta tcataagtta ctgtacactt ctctacgcct tctttttcaa
    39181 aacggcgaac ttgcagttca ttatctgctg actcgaccat agcctccagt cgttttatga
    39241 ttgcgactaa ttgtgaatgt gtcatcggag gtcctccttt tcttatttct gttatattgt
    39301 atcaaaagca tagcctactt gcattgattt tctctaaaaa aactcgtttt ttatgatttt
    39361 ttttctggta tttttccttc aggccaccaa agtttgatca aagcttgggt tccgtcattc
    39421 tcaaaacctt tatctgccaa ctcttcatat agtttcaatg cttgggtagt tgctggcaat
    39481 acaagatcca ttttttctgc ttcttctaat gcaatcttta aatctttgat aaaatgtttg
    39541 acaaaaaaac caggtgtgta atcttctttt aaaatacgag gagaataatt gcttaaagac
    39601 cagttagctg cacttccacc tgaaagcgtc tcaatcactt tctttaaatc aagtccgttt
    39661 ttttgtgcat agacaagcat ttccgtcatt cctgtcatcg tacctgcaat catgatctga
    39721 ttagccattt ttgtatgctg acctttccca gcagaaccat gcaatgtaaa tgtcgtacca
    39781 aattctttga ataaaggcag tacttgatca taaacggctt cttctccacc gaccatgatc
    39841 gtcagtgtac cattctttgc tcctaagtca ccaccggata ccggtgcatc taacgcatct
    39901 gcgccttttt cttttgctgt ttttgcaatt ttttctgcca ggcttggtgt acttgtagtc
    39961 aaatcaacta aaatatgtcc tgagatatct gcagaaaaaa tccccgactg tccatagtag
    40021 atttcttcta catctttggg gtaacctacc attgtaaaga gaatattact ttgttctgct
    40081 accgcttttg gtgtatctgc ccagatagct ccttctgtta ctaaaggatc agcttttgct
    40141 tttgtccgat tatagacagc tacttcgtgt cctgcttcta gtagatggcg tgcgacagca
    40201 cttcccatga cgcctgttcc gataaaacca agtttcattt tttcgacctc ctaaaaatca
    40261 aaaatccttg cttctatgct agtatacgct agaaacaagg attttttcat aaaaaatgtt
    40321 tgaattttat cttttaaatg aatttaattt tattttgatt cgttcaatcg agtcttcttc
    40381 ttcttttctt cgcatctctt cttcatgata aacaaccatg tcttgataaa attcgatcat
    40441 agcttcgccg aaatgtgtag atgaaatatc ataaagttta gcttctaaaa cttttggatc
    40501 tttaggaact tcactggaaa tataatcaat aagtgctggt gcaaagtctt cgtcggtttc
    40561 aaaagttttc cctaatgaag gatgatcgaa caatcggttc aaataagcat ttccttccac
    40621 gacacaaggt gttccggctg ccatcgcttc tgtataagta agcccttgtg tttctgaagt
    40681 agaagcactg acaaaataat ctgccgcttt ataataaagt gctacatcat tgttgtccac
    40741 ttctcctgtg aactgcacaa attcttctaa ctgcagttct gagatcaatt cctctaactc
    40801 ttctacataa ggtccttttc ctacgataac taatctggcg ttaggataag cggagatgac
    40861 ctgaggaaac ccattaatca aggcttggat atttttctca taagaaatcc tgcttaaaga
    40921 aagaatcatc aaatggtttt cctgaagacc tagtgactcc cttaatttgc tgatatcctg
    40981 ctgagtgata tcagaacgtt tgaatttttc aatgtcgata ccagtaggaa tcacgcgaag
    41041 cggtgctatt acaccatagc tgcgtaatgt atcaataaca cgttcacttg gacaaactac
    41101 acctgtcgta tgatttgcaa ataatctaga caagtatttt acatgggatt gcctgatcac
    41161 ttttccttta ccgatataat gaaggtagtc ttcatacatc gtatggtaag tatggatcag
    41221 aggtattttc aacttcttag ctaccatctt cccaagtatc cctgctccga attctgtatg
    41281 ggtatgaata agatctagtt ctagttcttt ggcaaccaaa taagcatacc acatgcctct
    41341 aacaacaact cttcgatcct tgaaagaaat aaatggtaca cttggcattc gaatcacatc
    41401 tttttccaac ttatccgcat taggatcggt cgttgtaaaa atatagactt catgcccatg
    41461 tctttctaat tcttgtttta atgttttgat cgatgtagca actccgctga cttgcggaaa
    41521 gtaggtatcg gtaaaaaagc cgattttcat gtttttcgcc tccaaactag tccttgacct
    41581 gatttacttt ttttaatttg ctagagactt tttcattcag tacactttcg tatacatttt
    41641 taagttcttc accgatttta ttgatacttc gctcttttgc tgtttgataa ccggcttgtg
    41701 tcgtactcgg tagttcttga ttggtaatct gttggatcag tcggataaat tcttcgtttg
    41761 tcttccccat atagcagttc ttgctatctt ctaaccagcc attatacact ggaatatctc
    41821 gaacaagtac gttttgtttg cttgctaaag cttctaaaac aacgatccct tctgtctctt
    41881 cataagaagg gaaaaagaat agatctgcac ctgaatacgc accttctatg atctctccac
    41941 gaatgtaacc aggaaacagg acattttcag gatgatcttc ttttacaatt ttccggatgt
    42001 tccgaggaat cgagtacatg ggaacatgac caaaccaaat aaatgtgtat tcgggcatct
    42061 tcttagcaat ttctacgaaa tcaatgattc ctttacgttc gaaaaacaaa ccgacacaaa
    42121 tgattacttt ttgatccgga gacagtttga aatattctct gaacttttgt tctttcattg
    42181 gatcagggtg atatttctct aagtcgatcc cattggaaat agcttgaatc ggcacacgga
    42241 taccatagct ttccaacaac tgttttgaat aaggtgttgg cgtgatcaga tagtccgctt
    42301 tttggtacaa tcctaccaga tattttttta cgataggaga aagctggttc gatccgataa
    42361 aggaatttcg gaaatcttcc tctgtagaat gcgcatgata gacaactttt tttccttctc
    42421 ttctggcttt attgaccata ttatgactat tgattccgta tgtattgatg tgcaggatgt
    42481 cataatcttc tttttcatct agtgtataag agataccgac ttccgtcaga gcacgttttt
    42541 gatgatcaag cgcacgcccg attccagatt ttgcaagcat cttttcactt tcaaaatata
    42601 ataatacctt caccttacgt cccccttcac ttatatagta taacatagcc tacaaactgt
    42661 cactcaaact taagccctat ttttgtctat tcttactgac aaaaacgttt tcttaaaaaa
    42721 gaacaaaaaa actggcgtag ctcttttaca agccacacca gcttttgata cgttgtttat
    42781 tttacatatt catgaacaag ttcaacgact tcttccatcg tatcgcattc tttcaatgca
    42841 cgatcagcaa gttcagccat tttcgctgtg tccaagcgtt tcattaaact acgcgtttta
    42901 agaatagatg tcgcactcat tgagaactca tctagaccca tacctactag caatggaaca
    42961 gctgtttgat ctccagccat ttctccacac atacctgccc attttccttc agcgtgtgct
    43021 gcatcaatta catttttgat caaacgtaaa attgatgggt tatatggttg gtacaagtaa
    43081 gaaacgcgtt cgttcatacg gtctgctgcc attgtgtatt gaatcaaatc gttcgtacct
    43141 acagagaaga aatctacttc ttttgcaaac ttgtctgcta agactgctgc tgctggaatc
    43201 tcgatcatga tgccgacttg gatcgtatca gatacttcct tgccttcact tatcaatttt
    43261 tgtttttctt cttcaaagat cgcttttgct gcgcggaatt ctttgagtgt agctaccata
    43321 gggaacatga tacgtaaatt accatgaaca gatgcacgaa gcaatgcacg catttgtgta
    43381 cggaacattt cgtcgccttg ttcagataaa ctgatacgca atgcacgata tcctaagaat
    43441 ggattcattt catgaggtaa ttgcagatat ggtagttctt tatctccacc gatgtccatt
    43501 gtacgaacaa ctacaggttt tccttccata ccttctaata cagctttgta agcttcatat
    43561 tggtcatctt ctgttgggaa gtctggagaa tccatataca ggaattcagt acggtacaga
    43621 ccaactgctt ctccaccatt attatggaca ccaactagat cttttggtgt tccgatgttt
    43681 gcagctaatt caaaatgctt gccgtcagct gtgacagttt ctgcattttt taatttttcc
    43741 cattctgctt tttgtgctgc gtaatctgca cctgcttttt caaattcagc tttttgttca
    43801 tctgtaggat cgatgattac atcgccttcg atcccgttga cagccaaaat atcgccttct
    43861 ttgactttag cagtaatttc ttttgtccca acgattgctg gaatttctaa agaacgtgcc
    43921 atgatagcag aatgtgaagt acgtccacca atgtctgtta caaacgcttt tacaaaattg
    43981 cgatctaatt gtgctgtatc acttggagtc aagtcatgtg caacaacgac cacttcttcg
    44041 ttgatcattg atggatttgg taaagtaacg cctaataagt gcgctaaaat acgtttagca
    44101 acgtcacgaa tatctgcagc acgctcttgc atataagcat tatcttccat tgcttcgaac
    44161 ataccgatat acatatccgt tacttctttt agcgctgatt cagcatttac gctgttgtct
    44221 ttaatatttt gcttgatttg acctaccatt tctggatctg aaagaaccat caaatgggca
    44281 tcaaatactt gcgcttctgc ttcacctaag ctttgcgctg ctttttcacg aatttgctgc
    44341 aattcttcag tagatttagc taatgcagca tccaaacgag cttcttcagc cgcagtatct
    44401 tctactgttg ccttactgaa tgttaaatcc ggttgaacta gcaggtaagc ttttgcaacg
    44461 gctacaccgt cactagcggc aatccctttt agcatttcaa ccattattca gataagcctt
    44521 ctttcttcat tgtttcaacg attgctgcca ttgcatcagc ttcgtcagca ccttctgcag
    44581 taatagtaac atcagaacct tgacctacac ctaaagacat aacgcccatg attgatttca
    44641 agtttactga tttaccttta tactctaagt ttacatcaga gttaaatttg cttgctgttt
    44701 gtactaatag tgtagctgga cgagcgtgga tcccagtttc tgctactacg tgaaattctt
    44761 tcttttccat attaatcggt ctcctttaag tgagtgttgt ttttatgtga gggttttctt
    44821 ttttagtaat tcagagaatc ctaacaaatg ccaccctttc atctgtaaag attaacattt
    44881 tttttcgtta gatacaacag ttttcattca atttcagata aaagtattca aattattccg
    44941 gattcttttt catccttttc ttcacatttt ataacaaacg tgtttatttc ctttttcttg
    45001 tcgctttctc ttctcctgac gtttatcatt ctttcctttg accctctttg ttttcatatg
    45061 aaacgaatta cttgcttccc tttttatttt tagtataata agagtcaaag gtcaggaatg
    45121 gtcaatagag atttcacctt ttctacctca taaatctctt aaaaaactag gggttattct
    45181 tttacctcat gaaaaacgag atgtaaaata tggatgtacc catttttgtg aaaggacgtg
    45241 aatgattcat gctttgtcaa aactgcggca agaatgaggc aacgattcac ttgtatgcca
    45301 ctgtcaatgg tcagcggaca caactcgatt actgtcagag ctgttatcaa aaaatcaaaa
    45361 atcaacaaaa tggaggtctg actaatatgg cccaaaatga tccatttgga tttggcagtt
    45421 tggacgatct tttccgttcc atgtctcgcc aaatgcaaca gcaaggaaat tatgagcaaa
    45481 caccaccaac acaatttggc ggaaacaaca acttcaatgg tggtcagcca cctcaaggca
    45541 atacagaagg tttattggga gaatacggaa tcaatatcac agaacaagca cgacaaggtg
    45601 atatcgatcc tgtgatcgga cgcgatgacg aaatcaaacg agtcattgaa attttaaatc
    45661 gccgaaccaa gaacaatcct gtcttgattg gagaaccagg tgttggtaaa acagcagttg
    45721 ttgaaggttt agcacaaaaa atcgtagatg gtgatgtacc gcaaaaatta atggacaaag
    45781 aagtcattcg tttagatgtc gtatctttag tccaaggtac tggtatacga ggacaatttg
    45841 aagaacgtat gcaaaaattg attgaagaga tccgtcaagc agaaaatgtg atcctattca
    45901 tagatgaagt tcacgaaata gtcggtgctg gttctgctgg tgatggaaat atggatgctg
    45961 gtaatatttt aaaaccagct ttagctcgag gagaattgca aatggttggt gctactacct
    46021 taaatgagta ccgcatcatc gaaaaagacg ctgctttaga acgtcgtatg caacctgtac
    46081 gggtagatga accaactgtc gaagaaacga tcagtatttt gaaaggtttg caaaaacgtt
    46141 atgaagacta tcatcatgta aaatatactg atgaggccat cgaagcagcc gcaactttat
    46201 ccaatcgtta cgtccaagat cgcttcttgc cggataaagc catcgatttg ctagatgaaa
    46261 caggttctaa gaaaaacttg acgatccaaa tcgttgatcc taaaacaatc gagaaaaaac
    46321 tgcaaaaagc agaagaacaa aaagttttag cttctcgaga agaagatttc gaaaaagcag
    46381 cttattatcg cgatcagatc aataaacttc aaaaaatgaa agaacgtcag ctcactgaag
    46441 aggaaacacc tgtgattacc gaaaaagata tggaaaaaat cgttgaacaa cggacaggta
    46501 ttccagtggg tgaattaaaa gaaaaagaac agacacaact gaaaaactta gcagatgact
    46561 tgaaagctca tgtcatcgga caagataacg ctgtagatcg agtagcgaaa gcgattcgcc
    46621 gaaaccgtgt tggattaaac aaacagaatc gtccaatcgg ctccttctta tttgttggac
    46681 caactggtgt aggtaaaaca gagcttgcga aacaacttgc ctacgaacta ttcggttcac
    46741 aagattcaat gattcgtttc gatatgtctg aatatatgga aaaacatagt gtctctaaat
    46801 tgattggttc tcctccaggt tatgtcggat acgaagaagc tggtcaatta acagaaaaag
    46861 tacggagaaa tccttacagt cttgtcttgt tagatgaagt agaaaaagct catccagatg
    46921 ttttgcatat gttcttgcaa atcttagatg atggtcgatt gacagatgca caaggaagaa
    46981 cggtcagctt taaagatacg atcatcatta tgacaagtaa tgccggaact ggtaaagtag
    47041 aagcaaacgt tggttttggt gcggcacgcg aaggtgttac tcgttctgta ttgaaccaat
    47101 taaacaacta ctttacacca gaatttctga accgttttga cgggatcatc gaattcagtg
    47161 cattatcaaa agaaaacttg atgacaatcg tcacactaat gctagacgat gtcaaccaaa
    47221 tgctggcagc acagcaactt cacatcgaag ttcctacgaa tgtcaaagaa aaattagttg
    47281 acttaggcta tgatccatct atgggtgctc gtcctcttcg acgcacgatc caagaacaaa
    47341 tcgaagatgg tatcgctgaa ttttatcttg atcacccttc tatccatgag ttgaaagcaa
    47401 aactggataa agatggaaaa atcatcgtta cttctaaacc agaacgtttg gctaaagaat
    47461 cagccgaaga aacggctgaa taaatccagt tttatagcgt gagacggtat ttctttgaga
    47521 aatgccgtct cattcttttt tcagaaaagt caaaatactg ttcattttat aaaaaagaaa
    47581 ttataataag agaaacaagc aattaaaaat acataaaaga ggtgagcgcc atgaaattgg
    47641 taaatgtaac aaacagccat tcccgtcttg tattaaacca gcttgaaaac actgatgccc
    47701 atctagtcaa ggtctacaca gccggaaata ccactattgt ctacactgaa gcccctgaac
    47761 ataatgaaat tctgctgatc aatgacaaac gtaaaatcca gccgaaagaa atcgaagatg
    47821 ctaaaaatta tttcttagat aaaatcaaag acgccgttta ccacgaggat gaaatcaaag
    47881 taatcgaatt ggcaggcctt gttgaaatct cgattccaaa acatgaatta ggcgctacat
    47941 tagccgtgta aacaaatttt gaacataata attaaagagc gtgggacaaa agtaaagagg
    48001 ctctttgtca a
//
LOCUS       DASHWW010000014        47337 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.014, whole genome shotgun sequence.
ACCESSION   DASHWW010000014 DASHWW010000000
VERSION     DASHWW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.014"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            26..1390
                     /locus_tag="U2R64_000939"
     CDS             26..1390
                     /locus_tag="U2R64_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8917776.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            1561..2627
                     /locus_tag="U2R64_000940"
                     /pseudo
     CDS             1561..2627
                     /locus_tag="U2R64_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            2642..3310
                     /locus_tag="U2R64_000941"
     CDS             2642..3310
                     /locus_tag="U2R64_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917777.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            3330..3908
                     /locus_tag="U2R64_000942"
     CDS             3330..3908
                     /locus_tag="U2R64_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8917778.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            4309..5220
                     /locus_tag="U2R64_000943"
     CDS             4309..5220
                     /locus_tag="U2R64_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8917779.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(5598..6515)
                     /locus_tag="U2R64_000944"
     CDS             complement(5598..6515)
                     /locus_tag="U2R64_000944"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEM8917780.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            6717..7154
                     /gene="zapA"
                     /locus_tag="U2R64_000945"
     CDS             6717..7154
                     /gene="zapA"
                     /locus_tag="U2R64_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEM8917781.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            7212..7760
                     /locus_tag="U2R64_000946"
     CDS             7212..7760
                     /locus_tag="U2R64_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEM8917782.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            7875..10235
                     /locus_tag="U2R64_000947"
     CDS             7875..10235
                     /locus_tag="U2R64_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEM8917783.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            10322..10636
                     /gene="trxA"
                     /locus_tag="U2R64_000948"
     CDS             10322..10636
                     /gene="trxA"
                     /locus_tag="U2R64_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEM8917784.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            10818..12596
                     /gene="uvrC"
                     /locus_tag="U2R64_000949"
     CDS             10818..12596
                     /gene="uvrC"
                     /locus_tag="U2R64_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEM8917785.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            12741..13640
                     /locus_tag="U2R64_000950"
     CDS             12741..13640
                     /locus_tag="U2R64_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917786.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            13633..14895
                     /locus_tag="U2R64_000951"
     CDS             13633..14895
                     /locus_tag="U2R64_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917787.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            15056..16954
                     /locus_tag="U2R64_000952"
     CDS             15056..16954
                     /locus_tag="U2R64_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HEM8917788.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(17284..18003)
                     /locus_tag="U2R64_000953"
     CDS             complement(17284..18003)
                     /locus_tag="U2R64_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEM8917789.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            18339..18671
                     /locus_tag="U2R64_000954"
     CDS             18339..18671
                     /locus_tag="U2R64_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917790.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            18658..20661
                     /locus_tag="U2R64_000955"
     CDS             18658..20661
                     /locus_tag="U2R64_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEM8917791.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            20680..21150
                     /locus_tag="U2R64_000956"
     CDS             20680..21150
                     /locus_tag="U2R64_000956"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEM8917792.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            21171..21755
                     /locus_tag="U2R64_000957"
     CDS             21171..21755
                     /locus_tag="U2R64_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEM8917793.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            21770..22756
                     /locus_tag="U2R64_000958"
     CDS             21770..22756
                     /locus_tag="U2R64_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEM8917794.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            22746..23057
                     /locus_tag="U2R64_000959"
     CDS             22746..23057
                     /locus_tag="U2R64_000959"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEM8917795.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            23079..24860
                     /locus_tag="U2R64_000960"
     CDS             23079..24860
                     /locus_tag="U2R64_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEM8917796.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            24853..26229
                     /locus_tag="U2R64_000961"
     CDS             24853..26229
                     /locus_tag="U2R64_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEM8917797.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            26236..26871
                     /locus_tag="U2R64_000962"
     CDS             26236..26871
                     /locus_tag="U2R64_000962"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEM8917798.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            26901..28256
                     /locus_tag="U2R64_000963"
     CDS             26901..28256
                     /locus_tag="U2R64_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HEM8917799.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(28448..29842)
                     /locus_tag="U2R64_000964"
     CDS             complement(28448..29842)
                     /locus_tag="U2R64_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEM8917800.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            29934..30905
                     /locus_tag="U2R64_000965"
     CDS             29934..30905
                     /locus_tag="U2R64_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HEM8917801.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            30902..31684
                     /locus_tag="U2R64_000966"
     CDS             30902..31684
                     /locus_tag="U2R64_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HEM8917802.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(31853..32224)
                     /locus_tag="U2R64_000967"
     CDS             complement(31853..32224)
                     /locus_tag="U2R64_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8917803.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            32358..32801
                     /locus_tag="U2R64_000968"
     CDS             32358..32801
                     /locus_tag="U2R64_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEM8917804.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(32844..33653)
                     /gene="yidA"
                     /locus_tag="U2R64_000969"
     CDS             complement(32844..33653)
                     /gene="yidA"
                     /locus_tag="U2R64_000969"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEM8917805.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(33672..35039)
                     /locus_tag="U2R64_000970"
     CDS             complement(33672..35039)
                     /locus_tag="U2R64_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8917806.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEYIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(35023..35853)
                     /locus_tag="U2R64_000971"
     CDS             complement(35023..35853)
                     /locus_tag="U2R64_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEM8917807.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            36016..36453
                     /locus_tag="U2R64_000972"
     CDS             36016..36453
                     /locus_tag="U2R64_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEM8917808.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            36529..37149
                     /locus_tag="U2R64_000973"
     CDS             36529..37149
                     /locus_tag="U2R64_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEM8917809.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            37338..37844
                     /locus_tag="U2R64_000974"
     CDS             37338..37844
                     /locus_tag="U2R64_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEM8917810.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            37861..38760
                     /locus_tag="U2R64_000975"
     CDS             37861..38760
                     /locus_tag="U2R64_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HEM8917811.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            38847..39731
                     /locus_tag="U2R64_000976"
     CDS             38847..39731
                     /locus_tag="U2R64_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEM8917812.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(39923..39994)
                     /locus_tag="U2R64_000977"
     tRNA            complement(39923..39994)
                     /locus_tag="U2R64_000977"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39959..39961),aa:Arg,seq:ccg)
     gene            40054..41388
                     /gene="rpoN"
                     /locus_tag="U2R64_000978"
     CDS             40054..41388
                     /gene="rpoN"
                     /locus_tag="U2R64_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HEM8917813.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            41537..42628
                     /locus_tag="U2R64_000979"
     CDS             41537..42628
                     /locus_tag="U2R64_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HEM8917814.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            42669..43670
                     /gene="gap"
                     /locus_tag="U2R64_000980"
     CDS             42669..43670
                     /gene="gap"
                     /locus_tag="U2R64_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEM8917815.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            43780..44970
                     /locus_tag="U2R64_000981"
     CDS             43780..44970
                     /locus_tag="U2R64_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEM8917816.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            45074..45829
                     /locus_tag="U2R64_000982"
     CDS             45074..45829
                     /locus_tag="U2R64_000982"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEM8917817.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            45945..47243
                     /gene="eno"
                     /locus_tag="U2R64_000983"
     CDS             45945..47243
                     /gene="eno"
                     /locus_tag="U2R64_000983"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEM8917818.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        15746 a         8194 c        10064 g        13333 t
ORIGIN      
        1 aattgaattt aaggatgaat aaaacatgaa aatcgtgatc attggtgctt cccatgaagg
       61 catcacagct gccctaaatc taagaaaact tcaaccgaaa gcagaagttt tactgatcga
      121 tgaagatcat aaagatggac taggctatgt ttcaaatgga atcaaccttt atttaaaagg
      181 aaagatacgt agtttagctg aagttgccca taacatgcgg actcttcaag aaagtggggc
      241 aaaactgatc accgaatgga gagtaactga acttgatcca gacaaacatc agctcatcct
      301 cgcatccaaa gaaggaaaaa acgagaccat aacctatgat aaattaatcg tagcgacagg
      361 ttcctctcct gtcaccttgt ataaacaaat tgaagctgaa aatgtctaca cctataaaaa
      421 tctagtgcaa tctaagcaag tacttgccgc tttaaaagaa gcaaaagaag tagtgatctt
      481 cggtgctggt tacattggat tggaattagc agatgctttg agaaataaag gatacattat
      541 tcatctagtt gattatatgc cgaatgtttt atcaagatat ttcgataagg atatgatcaa
      601 cagttttcaa aatcagctgc aaactaagca aataaatttt tatccaaatg aattcttgat
      661 cgattggaaa aaatcagaag agaaagtagt atccgtacaa cttctgtctc aaacaataaa
      721 ggcagatatg gtcatttttt ctgcccaaac tcgtcctaat acgacattgt taaaagaaaa
      781 agtggctttg tatgaggatg agactgtgat agtcaatgaa tatctgcaga caagtgatcc
      841 ggacatctat gcgattggag atatcgtccc agtcagtttt gacaaaaata aacggcatct
      901 ctttttacct ttagttactc gagctgtaca tatggcaaga gcagtagcgc taactttgag
      961 tggtcagcca accgcttacg acctcagaca aaagataaca gcagcagtca ttatagacta
     1021 ctttttagga actgtagggc tgacagaaga tgaagcgcca ttcttggaac aaaataccgg
     1081 ttcgtgttca ggagaatttg atctatttcc acaatacgac gaagaaaaca aaacagtaaa
     1141 tgcaaagctg atctaccatc cggatacatt agaaataatt ggcggacagc tgataagcca
     1201 agaattctta ttatcagatt tgaacctgct tgcggatatc gtgaaacaca aaactacgat
     1261 tccacagcta gcagttgagg attttggatt tctgtctgaa tacacctctc gttttcacta
     1321 cctcaatgag ttagctttta aagtactagc taagagagca aatagcaata gagtagataa
     1381 aagactgtga gaaatatcac ggtcttttat tgtgtgggga tataataaat attaatcaat
     1441 cgagaataaa aaattcatat aatgaaatag cggaagaatt ttttgagcat aatattcgcc
     1501 aaaaatttat caagtgataa aattgttgta taaaatgatt atttcaggag gaggagttaa
     1561 atgtttttag cattaaatga aattatgcat tcaaagttac gttatgcgtt agttgcaggg
     1621 gtgatgtttt tgatcgccta cctggtattt tttttgactg ggtttatggc ttagctcaag
     1681 ataatcgaac agcagtcgac aagtgggagg cagattcgat tgtgctttcg aaagatgcaa
     1741 attcaaatct agggatgtcc atgattacta agaagatagc agaagaagtc gaaggtggga
     1801 aagtggcgta tcttgcccaa acacctggag tcgtgactag taaagacagt acagaagaag
     1861 gaaaaatcaa tgttagcttc ttcggtatcg ataaaaatca attcatcatg cccaatcttg
     1921 ttgaaggaaa agcttttgat aacgatgatg aggcagtagg cgatattagt ttgaaagaag
     1981 aatatggtct agccatagga gatacagtta agttatctgg tagtgacaag acgtttaaac
     2041 taactggctt tacggatcat gccaaattca atgtctcacc agttctctat acaaccatca
     2101 atgcttacca agaaatccgc ttcgaaaaag aagatacaag tgaaaatgca cggattaacg
     2161 caatagttgt cagaggtaaa atcagtaatt tacctgaaga tttagaacag atcaaaattt
     2221 ctaaattcat caatgaatta cctggatata atgcgcaagt attgactttt ggatttatga
     2281 tcggattttt gatcgttatt gcggctattg tgatcgggat tttcatttat gtactgacga
     2341 tgcaaaagat taatatcttt ggtgtaatga aagcacaagg gatcacagga ggatttattg
     2401 cgcgttctgt agtggcacaa acattcattt tatcatttgt tggtattctt cttggtctat
     2461 taggaacagt gggaacatcc cttgttctac ctgatgcggt tccattccaa agcaattggc
     2521 tgttttttgg cgtcattagc ttgttgatgt tagtagtagc tgtgttaggc gcactatttt
     2581 ctgttcggac aatcgtaaaa atcgatccgt tgaaggcaat tggataagaa ggaggaagaa
     2641 catgaaagca atagaattta aagaagtaga aaaaagtttc caagatggcg accaagtagt
     2701 taaagcattg aaagaaacaa ccatgagtat cgataaaggg gaatttgttg caatcatcgg
     2761 tccttctggt tcaggtaaaa gtactttttt gactttggca ggcggattgc agacgcctag
     2821 cagtggctct gtatttatca atgatcaaga attcagtaat caaaaagaaa gcgaacgcgt
     2881 taaactacgt tttaaagaaa ttggctttat tttgcaagct tccaatctgg ttccttttct
     2941 gacagtaaaa aagcagttat tattagtaga taagattaaa catgaacatc gtcaaaaaga
     3001 agcaaacgaa ttatttgagc agcttggcgt ggataagttg atcaacaagt atccagaaga
     3061 actatctggt ggagaacggc aaagggtcgc aatcgctcgt gcattgtaca atgatccgtc
     3121 cattattcta gcagatgaac caactgctag tttggattca gaaaaggcac gagaagtagt
     3181 cgatatcttg gcaaaagaat caaaagacaa aaataaagca acgatcatgg ttactcacga
     3241 tacacggctg attgacaaat gcgatagaat atttatgatg gaagatggtg tattgaaaga
     3301 aaaagaataa ccaaaaagca ggtggaaaaa tggtccatcg atacaacaaa gatacacagc
     3361 aaaaaatttt gaaagaagcg actgacttgt ttatgtccaa gggatatctc ggcacttcaa
     3421 caagagaaat cgcacaaaaa gttgggatca cccagcccaa tctctatcat tatttcggtg
     3481 ataaagaaaa actatatacg gcagttttag aaaaccactt aaaagatgtt ggaaaagctt
     3541 tgagagaaat cgttcaaaca agcgaaacgg gatttcaagt aaccttgaca aaaatggcgc
     3601 agtttttgat tgagacacat ctggtcgatt tgtttctgat gcttcacgat cttgaaagca
     3661 atctttcaaa ggaaacaaga gatcatcttt tctttctatg gaagaaaaat tatcgtgaac
     3721 cttttgaaga aatcttttca gcaaaccaat ctgtgctaag aaatgggatt tcaaaagaaa
     3781 tcgcagcaag gcattttttc ttagtgttag caccttacat cactcggtcg aaaagacctg
     3841 tggaagaacc gctaaatgtg gcgcaattga tcgatttata tttgaatggt gtattaggag
     3901 aagcgtaaag ctgttatata gggagaaaat agttaggtga agaagcaaga tatgacgaag
     3961 atcgttatat cttgcttctt tatataggta gtttttcata aatacaaatt tgttattctc
     4021 tcatgattat cagggtatat ttttatttat tatgtcggtg ttccaggaag tgttttaatt
     4081 taataacgaa gaaattaatt gtttgtagaa tgaaggaaac tatttattgg gtagatgaat
     4141 caccacgaat agtcaaaagg agatttcagg atatgccaaa aatgaaaaaa atcattttag
     4201 cagtaatgtt attttctacg gttatatctt ttacagcccc ttttttgctt acttaagctg
     4261 attttaagtt ttggccctta gtctggatct acgaggtgag agtcaagaat gaaaaaaata
     4321 attggagctt ttgtatttgc aatcattatc attattatct gttttcaaat agatgttttt
     4381 ggtcaaaaaa agatagttgg acaaacggtc agcagtacga acagtacggt tacaaagaca
     4441 aaggaatcat ttgatgatac agaacaagag acattaatca aaatcggaaa aaatgaccgt
     4501 acactatata cagatgactc gctaactacc ccacttgcaa ctataaacgg cggagagctg
     4561 gcggagtttc tttctgaaac aaaaaatgct tatcagatca agacaaatga tggctatact
     4621 ggatatttag ccctcgaaga tggaaccaaa gtcacaaaga atatacaaac aaaaccggaa
     4681 gagctatctg atgcagtgat tgtattagat cctgggcatg gcggaaatga tactggggca
     4741 ttaagcaatg atgaacaaac agaagaaaaa gatataacat taagtacagc cataaaagta
     4801 aaaaaggcgc tagaggatgc tggagcaacg gtttatttga cccatactac agatgaatta
     4861 gtacagcttg gagatatatg cgactacagt gaagaaaaaa aggcagatgt ctttatcagt
     4921 ttacacgcag actctacgga atatgcgaat gaagcaactg gaatcacgac atattattac
     4981 tatggacaag aggaaacatt agcacagaca attgctgact ccttcactga tctgcctctg
     5041 gattcaagag gaatctccac tgggaactat caagttcttc gagaaaatct tcaaccttct
     5101 attttaatcg agatgggtta tatgaataat gatagtgatt taaaggaatt agtaacagac
     5161 agttatcagc agcagattgc tgcaagtttg acacaagcat tgaccactta ttttcagtaa
     5221 taaataagcc cagccaaaca aaaatagctc ctcatatttt tcgtttggcc gggcttatta
     5281 tcgcagatgc aagcttttaa acaccgttta aggaagaggt cgtgagcctg ccgttcaact
     5341 ctgagtcaca aggagcaatt tcaaaaaaca gcttctcatg tttgatgact attgtgactt
     5401 gtgaccgagg agttggcatg agaacaccgt ttaagaaaaa ggttgtgaaa tcaacgtttt
     5461 gttctgagta ttagagaaac aaacggaaaa atagttcctc atattttgcc gtttgttgag
     5521 ctaataccga ggatcagatg attgaacacc gtttattcgg aacaagggac tgtgacatga
     5581 cttttgtcac agttccatta tttttttagt agcttcaaag ctttttctgt attggcaaaa
     5641 tgaagtttgg catatttttc aagcataggc atgccgcctt tctccaatag ttttgccgct
     5701 acttggtcag atttcgttcc agctcctgac ggaagggtga ttccagcttc agctgatgct
     5761 ttgtctaact cttccaaaaa gctggcacga ctgatgatag aagcagcagc aacagctaaa
     5821 tgatattgtt ctcctttagt aacgaagtac agtttttctt gtaattgatt tttttctaaa
     5881 cgcgcatatt ttttaaaatt tgcttccggc gtaaactgat cgatcaaaat cgcttctggt
     5941 ttttctggct cgattttttt tagcagcaaa tggatcgctt gattgtgcaa agcgactttc
     6001 atccgaacgg cattgtattt tggttggatc tcattgtatt tttctggaga taagacaagc
     6061 agtttatagg ggatggtttt ttttaagatg tcagcaagct ggatgatttg gctatctttt
     6121 aactcttttg aatctctaac accaagttta cgtaattctg caagctgatc acgtttcaca
     6181 taagcagcac atactgttag cggaccgaaa tagctgccat ttccgacctc atcactacct
     6241 aaaacggata attgactgat attttttggc aaagaagagg ctgtttttgc tggcttggct
     6301 tgtttatcct gtgcctcccc ccatttatca gcttctattg ctgcattcgt accttgaaac
     6361 atcacttttc cggatgtata agcggtaatg gtcgtcccgt ctttttttgc agcaaagcta
     6421 gtataaggaa tctgtttatt taacaaataa gagcgatagt atgctttcat ttgactaagt
     6481 tggtcgtttg ttgctttgat aatgacgttg ctcataaaat tctcctcgtt tttatacata
     6541 aaactatacc gcaactcacg acttttcgtt ttctaagaga ttgcgagaca tagcattttt
     6601 ttaaagttta tcatataata gttaagtatg tgaaaaatat ttgtggagaa cggtgaaaga
     6661 accaacttca tggtacacta aataaaactt tcatcaaata ggaggaaatg attcgtatgg
     6721 cgcacgaaaa aacacgctac aaagcggtga ttgccaacca aacatatact attatcggac
     6781 gggaaaccaa gcatcatatg gatatcgtaa cgaagctgat caatgaacag ttagcagaat
     6841 tgaaacaatt atcaccacaa atggataatg aacaagcagc aatcttgatg gctgtcaatg
     6901 cgctttcgga tcaattgaag aaacaagaaa gaatattgga gctggaagaa gaaacagcag
     6961 aattaaagaa aaaaatgatc aaatttacag agcttgaaaa tcgtgtgaaa cgcattgaag
     7021 caatcgagaa cgaagctcgg gaagtattga aagaaaatgg tcaagcagat cataccatta
     7081 aaaatcatgt ggaagcacaa cagattttaa acgagaaacg aaaaggacaa attaaacaaa
     7141 aatcttctaa ttaagatcct tttatcaaaa taagaaaaat ttaaaaaagt tagaagagaa
     7201 aggaacgtag catgctgagt ttgctgattt tatttttatt gctaattgcg tttttttctg
     7261 gagcacgtcg cgggtttgct ttgcaaatca tattcgcgat tggatatgta ttgtcattta
     7321 ttgctgccca gcatttttac aaaccattag caagtcattt ggaattatac attccatacc
     7381 cagctgtcac cccaacatca aagttagcat tttttgatca ggtatttgcc tttcacctag
     7441 atgaagcttt ttatgcagga actgcttttc tgattatttt gctaattggc tggctgctta
     7501 cccgatttgt gggggttttt gtccatggat tgacgtatgt gccgatcttg agacaggtag
     7561 actggattgc aggaggcatc ctgtcactaa tcatggctta cgttactata tttttgattt
     7621 tgcagttact tgcctttgtt ccattagatg tggtccaaaa tcaattcggc gagcatagtt
     7681 tcgctcgttt tatcgttgag agaacgccat ttcttaccaa caagatgtat gagctttggg
     7741 taacgaatat tttgaattaa ggaaaatagt gctggaaaat atttcgtttt ttgtacagag
     7801 tagtttattt aagaaggctg cgtagcgtat gtccggcaca gctctttttt catagtgaaa
     7861 gataaggtga taaaatgaat aaccgaatcc ttgaaacatt ggaatttgaa aaagtcaaac
     7921 agatggtcag acaatttgta gtgactgcac aaggaaaaga agaactggca gaattggtac
     7981 cagtgagtga gaaacaaacg atcacaaact ggcttcaaga aactgaggat ggattgaaag
     8041 tgcaacgtct gcgaggcggg atccctatac ctaaaattga aaatatccgt ccccatatga
     8101 aacggattga gatcggagca gacttgaatg gagtggagct tgcacaagtt tccagagtat
     8161 tgtctacgac aagcgaattg aatcgtttca ttgatgatct ttctgacagt gaaatcgaat
     8221 ttgcacgttt gtatatgtgg gcagatcagt tagtcacgat ccctgttttg agccgccgtt
     8281 taaaggaagc aatcgatgaa gacggacgcg tgactgatga cgcttctcct gagttaaaga
     8341 gcataagaca gaacattcgg cgaagtgaac aagctgttcg tgaacagtta gatgggatcg
     8401 tccgtgggaa aaatgcaaag tatttaagtg atgcgatcat caccatgcga aatgaccgct
     8461 acgttatccc agtcaaacaa gaataccgcg gtgtatttgg cggtgtagtc cacgatcaaa
     8521 gtgcttcagg tcagacttta tttattgaac caaaacaagt ggtggatttg aataatcgtt
     8581 tgcgtcaata ccaaatcgct gaacgaaatg agattcaacg tattttaagt gaactttctg
     8641 ctgaacttgt tccccatcgt caagaaatca tccacaatac ttatgtgatt ggtaaaatgg
     8701 atctgatgaa tgcaaaagca cgatttggta aagaagtaaa agccatcgtg ccgggaatca
     8761 gtgaagacaa tcatgtcgtc ttgaaacaag caagacatcc actgatcgat caggaaaaag
     8821 tagtttctaa tgacatcaca atcggaaaag actatcaagc catcgtcatt acaggaccta
     8881 acacaggtgg gaaaacgatc acgttgaaga ctttaggtct gttacaactg atggggcaag
     8941 caggattacc gattcctgca ggtgaagaaa gtcaaatcgg tatttttgag gaagtatttg
     9001 cggatatagg agacgaacag tcgattgagc aaagtctatc gaccttttct tctcatatga
     9061 cgaacactgt agatatttta tcaaaagtca atgaaaaaag tctggtatta tttgacgagc
     9121 tcggtgcagg aacagatccg caagaaggtg ctgctctagc aatcgcaatc ttagatgatc
     9181 ttggtaaaaa gtctgcttat gtgatggcaa caacgcatta tcctgaattg aaagtttatg
     9241 gatataatcg ggcaaatacg attaatgcca gcatggagtt tgatgtggat acattaagtc
     9301 caacgtatcg tttgctgatt ggcgttcctg gacgaagcaa tgcgtttgaa atctctagcc
     9361 gattaggtct tgatacagaa gttattgatg aagcgaagca gttgatgaat gatgagagcc
     9421 aagatttaaa cgaaatgatc acagatttag agaatcgccg gaaaatggca gagaccgaat
     9481 atctggaaat gcgtcatttt gtttctgagg cacaagaact tcacgatgat ttgaaagaag
     9541 cttacagcta tttctttgaa gaacgtgaaa aagaaatgga aaaagcaaag aaaaaagcaa
     9601 atgaagtcgt gtcagaggcg gaagaaaaag cagaaaaaat cattgctgat attcgtaaaa
     9661 tgcaacagca gattgggcaa ggaaatgtga aagagcatca gttgatcgat gcaaagaccc
     9721 aattagcaaa tctacatcaa gaagaaactt tgaagaaaaa taaagtattg aagaaggcga
     9781 aagaacaaaa aacgttgaaa ccgggagacg aagtgttggt tacgacttac ggccaaagag
     9841 ggacgctttt acgtaaaaac gggaatcagt ggcaagtaga aatcggtata ttaaaaatga
     9901 atgtgtccga agacgagctg acgcctgttg ctcctcaaaa agagccgaca caacgagtta
     9961 tccatgctgt acgatctgaa tctagtagtc acgtgccgaa tcaattggac cttcgaggaa
    10021 aacgatacga agaagcgcta agtgaggtag atcaatattt ggattctgcc attctagctg
    10081 gttatcctca agtgactatt gtccacggaa aaggaacagg cgcacttcgc aagggaatta
    10141 ctgattatct taaaaaccat cggagcgtca aaagctttga gtttgcaccg gcaaaccaag
    10201 gcggaaatgg tgcgacaatt gttaaattta agtaaagctt actaaaggta agcagatggt
    10261 tcgctatcca agtatagaaa tgctatacta gtcatagatt ttaaaaatgg aggtctttga
    10321 tatgtcacaa gtaattacag ataagacatt taatgaagaa acagataaag gacttgtatt
    10381 gattgatttt tgggcaactt ggtgtggtcc atgtcgtatg caagcaccga ttttggatca
    10441 gttggaacaa gaatatgatg aagaagaatt cagaattgct aaaatggatg tggatgaaaa
    10501 tccagaaact cctcaacaat tcggtatcat gagcattcca acattaatgt tgaaaaaaga
    10561 tggtcaagta gtagaaaaag ctgttggtgt tcattcaaaa gaacaactac gtcaaatgat
    10621 cgatcaatat ttataaaaac ttacagcaaa aataagctga gggtgggact gaatccagtt
    10681 ccgtcctcgg tttttttgcg gttgagttaa ggttattcaa attaatattt tttgagtata
    10741 attacgttgt caggctggat tgtttttttg acagacatgc tataataact ttaattgaat
    10801 atgaagggga gtaccagatg aacgaacgaa tcaaaaacaa attagcttta cttcctgatc
    10861 agcccggctg ttacttgatg aaagataaaa atggaacgat catttatgtc ggcaaagcca
    10921 aaatattaaa aaatcgtgtc cgctcatatt ttactggtag ccataatacg aaaacggaac
    10981 ggcttgttag tgaaatcgaa gactttgaat acatcgttac agaatcgaat atcgaagcat
    11041 tgctcttaga gatcaatctg ataaagaaaa atgatcctaa atacaacatt atgttaaagg
    11101 atgataaaac ctatcctttc cttaagataa cgaatgaaaa atatccccgt ttggtgatta
    11161 ctcgtaaggt actaaaagac aaagcactgt attttggacc atatcccgat gtcggtgcgg
    11221 cgaatgagac aaagaagatc ctcgatcgat tatttcctct gagaaaatgc aaacctagtc
    11281 agacgaagga gccttgtctt tactatcatt tgggacaatg cctgtgtcct tattatttcg
    11341 acgtagatcc gaaagtctat acgaaaatcg ttgatgaagt gaaaaacttt ttaaacggag
    11401 gacacgaaaa aatcgagtca gagatccatc agaaaatgga aaaagctgct gaaaacatgg
    11461 agtttgaaaa agctgcagaa taccgagacc agatccgtgc cattgagaca atcatgactc
    11521 gccaaaaaat gacaaatact gatttactgg atcgagatgt atttggttat gcgattgata
    11581 aaggatggat gtgtgtccaa gtgtttttcg taagacaagg aaagctaatt gaacgagatg
    11641 tttcaatgtt tcctttctat aacgaagcag aagaagattt cttgacttac ctcggtcagt
    11701 tttatcagga aaatgagcat ttcattccta aagaagtctt gattcctgat acgatcgaca
    11761 agcccagtgt agaagctttg ttagctacga aagtgctgca accaaaacga ggagaaaaga
    11821 aaaaattagt tgaattggcg agtaagaatg cctcagttgc tttgaatgaa cggtttgatc
    11881 tgattgccag aaaacaggaa cggacgatcg gagcagttga acgtttagga aacgcgatga
    11941 atatcccgac cccaatacgt atcgagtctt ttgataactc taatatcatg gggacgaatc
    12001 ctgtggctgc gatggtcgta ttcattgatg gaaaaccggc aagaaaagaa tatcggaaat
    12061 ataaaataaa aacagtcaac ggaccggatg attatgcatc aatgagagaa gtcatctatc
    12121 gcagatattc gcgagtgatt cgcgaagggt tgcctttacc tgatttgatc ttgatcgatg
    12181 gaggaaaagg acaagtagat gtggcaaaag atgtcttaga aaatcaatta ggaatcgata
    12241 ttcctattgc tggcatggta aaaaacgata aacataaaac aaatgagttg ctattcggta
    12301 cagatttggc tgtagtaccg cttgagcgaa attcaccaga gtttttctta ctccagcgaa
    12361 tccaagatga agtccatcga ttcgcaatca ctttccatcg gcagctacgc agtaaaaaca
    12421 gttttgcttc ccgattagat gaaattgaag ggttaggacc aaaacgaaaa aaaatgctgc
    12481 ttaaagagtt caaatcgttg aaaaatatca cagcagccac gacagaagaa ttacaagaaa
    12541 tcggactgcc gaaaaatgtc gcacaaaacg tatttgataa attacatcag gaatgaggaa
    12601 agggcacttt acaaagaaag taaagtgtcc tatcatttta tgtacaacaa aaagagcgtt
    12661 tacgttttgt tggtaaataa taaatcgctt acgtctggtg tctaaggata tatgtgattt
    12721 cttgaagaag gagtgaagaa atgttagaag tcaaggatct tgttaaaact tttgggaact
    12781 acacagctgt cgatcatgtc tctttccaaa tccccgatgg aaaaatcatg gggctaattg
    12841 gccaaaacgg ggctgggaag acaacgactt ttcgtttgat cttggatttt ttgacacaag
    12901 accaaggaga agtgttatgg aatggccatc atcttgggga gaaagattat gatgtcatcg
    12961 gttatcttcc ggaggaacgg ggactttatc cgaaagtaac gattcaagac caactgcttt
    13021 attttgcaga acttagaggg aaatcaagaa aagagattga accaaaaatc gacttttgga
    13081 tggaaaaatt tcaggtaaaa gggaaaaaga cggataaagt aaaatctttg tctaaaggaa
    13141 atcagcaaaa agtccagctg atcgccacgt taatccatga acctaaattg atcattttgg
    13201 atgagccatt cagcgggtta gatccggtaa atgctgaatt gctaaaagat ggaatattgg
    13261 aattgaaaaa acatggttca tgtgtcattt tttctagcca caatatggat aatgtagaaa
    13321 aaatctgcga tcatttgatc atgttgcgaa acggaaaaat ggttttgaat ggaaaagtac
    13381 atgagattcg tgaatcattt ggccgtacga agttattctt ggaatctggt ttaagccaac
    13441 aggaagtaga agaaatcgaa ggcgtgaaaa aagtgatcct tcatgaagac aatacgttag
    13501 agattacctt agaagatcct gaagctggga aagaaatctt tactcgtgcg actcagttcg
    13561 gctacattcc tatgtttaac cagcaaccgc caactttgga agagattttc aaattgaaag
    13621 caggtgaaat cgatgcgtaa gttttggatt attaccaaag atgtctattt aaaaaatgtt
    13681 aagtcgattt ctttcttgat catgatatta gtccctttta tcatgctggg tatcatttat
    13741 gtagcaggaa actttgctca acaaaatagt gatgtcaata aaatcggcgt attggctgat
    13801 aatgagcaaa tcagtcagca aatgagccaa gtcaaaacag atgattttga gttcaaagca
    13861 gttgattctg aagaaaaagc acaaaaagag ctttcggaag aaaaaatcga tgcgtattta
    13921 gtagtctcaa ctgagaatga taagataaat gggatgcttt atagcgaaaa ttcattagga
    13981 caaagtacac aactactgat acaacaacaa ctgactggct tgcaatcgat gcttcgagcg
    14041 agtcaattag gcatttcacc agaagaagta gctagcttga gccaacaagc aagtttgact
    14101 cgacaaaaag tcaattttga ttcaaaagga aaaatgacag tcggagaaga taactcgaca
    14161 gtccaatacg tcgtaagtta tgtagcaacg attgtcttgt tcattattat tttgacgtat
    14221 gcgcagatca ttgcacaaga gatcgcttct gaaaaaggca cgcggatcat ggaagtgatc
    14281 ctgtccagta cgactgcaca aaagcatttt tacggaaaat taacaggtgt tttacttgtt
    14341 gcattaacgc aaatggcatt atacggtatt atttttggta taggatacag tcaattcaaa
    14401 gatatggaaa tggtcaaaaa tatattagac ggtatctcat tggataactt gattggacca
    14461 ttcttgtggt attctcttct attcatgatc tttggcattt tgattttttc tgttttagca
    14521 gctttatgtg gctctttggt caacaaagca gaagatacag caaaagcaat tttgccagtg
    14581 acttatctat ctctaggcgg atacatgctt ggattgatac taggagcttc agatccaaac
    14641 aatatcgtta ttcggatcac ttcgtatatt ccattcttat cttcatatat tatgccgatt
    14701 cgcttagcaa atgagacagt cggtatgggt ggagcattga tttccttgtt ggtacttgta
    14761 gccgtaacat tcttattgat gatcttgtct gcaaacatgt acaaatcgaa tgtactcgtt
    14821 tatagcgaag gcggattatg gagttcattg aaacaatcga tttcaattat gaggaatgaa
    14881 cgaaaaaaag cataaaacaa tcctaaaata cagaaggaag ctggacatct attgttccca
    14941 gcttcttttt gtatagacct attttattta ttttactata ttggatatat attcattgaa
    15001 aatagtgtat aacaacttta taatattgag tataccaatt tttggaggcg ttttaatgga
    15061 ccgttattta gatttacttt cagaaaaatt cccctcaacg gaggatgtca tcacggaaat
    15121 catcaatctc gaagcaattt tgcagcttcc aaaaggaaca gagttatttt tgagtgatat
    15181 acatggcgaa tttcctgctt ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga
    15241 aaagatcaaa gacctttttt ctgaacaaat gacggaaacg gatatcagcc aattcactat
    15301 ttttacggct tatccagaat atgcattaac gactgattgg tacaaagaac aagataaatc
    15361 gcagctgatc catcatttga tcgatctttt acggtttacg acagtcaaat atacccggtc
    15421 aaaagttcga aaaggattgc cgaaagaata tagctatatc attgaggaac tcttgtatat
    15481 cgatgaccgt atcaatggaa aaaaagacta tgtaaaaaaa atcattgaac aacttgtttt
    15541 gatgaaggaa gaagaaaaat ttttaacgaa acttgcacag acgatccaaa aatctgtcat
    15601 cgatcatttg catatcgttg gagatatttt tgaccgagga actcaagcag ccaaagtgat
    15661 ggatcgaatc atggattttt cttctgtaga tatccaatgg ggaaatcatg atattttgtg
    15721 gattggtgcg tattgcggct ctgaggcatg tttactgaca cttttacgga ttgcagcacg
    15781 ctataattat ttatttgaat tagagaaaga atatgggttg aatttacgtc cattgttttc
    15841 ttttgctcat caaacttatc agaagaatcc agtatttgcg cctaaaaaca gtaaaaatct
    15901 atccgaaaga gagcaagaag aattagaaaa aatccatcag gcactttcta tccttcaatt
    15961 caaatcagaa catcagttat tggatcgtcg acctgaattt aaaatggacg atcgtaaatt
    16021 gctggaaaaa atcgactatg aagcatcaac gattgattta gaaggtcagc tctatgagtt
    16081 gaaaggaact tgttttcaaa cgatccagcc agatgatcca aaaaaattct tggaagagga
    16141 acaaaaagtg attgatagtt tgatgtattc attccagcac tctttgagaa tgcaaaaaca
    16201 tatgacgttt ttgatcgaaa aagggggaat gtatctcacg aacaatcagc atgtgctgtt
    16261 tcatggctgt atacctgtag acgagaaggg acagctctta gcatttgaat tagaccaatc
    16321 ttatcgcgga aaagaactgc tgggcttttt tgaaaaacag ataactgaaa gcgcaaaaga
    16381 tctgactgca aaagaagatt tagcaaccga tttgatttgg tatgcgtgga gtgggccatt
    16441 ttcgccttta ttcggcaaga gtaaaatggc gacttttgaa cgttattttc tcacagagcc
    16501 tcatacgcac gtcgagaaaa gcaatcctta ttatcacttg cgagatgaag agtggttcag
    16561 tgaaaaaatt ttagcagaat tcgacacaaa agaagaaggg tcagcaatca ttaatgggca
    16621 cacgccagta aaagtaaaaa aaggggagtc accgatcaaa gcaaatggaa aagtatttgt
    16681 cattgacgga ggtttatcca aagcttatca aaaaacgaca ggaattgccg gttattcact
    16741 attatgcaat tcttatggtt tccaaatcgt gacacattat ccgtttttgc ctattgaaca
    16801 acaatttgca aaaaaatccg accaaacaaa tgtgaaaaaa gtaatcgaac agcaactacc
    16861 acgcaaactc aatcgtgata caacaaaagg tatggaactg cagcagcaga ttacccagct
    16921 caaaaggctg ttggactatc gaaaggacga ttgagaagaa ttccagtgaa cattgttcca
    16981 tagactggag actgagacaa aagtcgtgtc gcagtctctt tttccggata aacggtgttc
    17041 ttctgccaac tcctcggtca caagtcacac tattcaacaa acatgaaaag ctgttttttg
    17101 aaattgctcc ttgtgactca gagttgaacg gcaggctcac gacctcttgg tataaacggt
    17161 gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtga aaagccattt
    17221 tcacaaaatt tttcttaata ctcgaaacta aacagctttt tcacaacccc ctcagaaagt
    17281 ctattaaaat tcattcacaa agaaatcgaa taagcgctgt tcagatggat gtacacggtg
    17341 ggtaagttcc ggatgccatt gaacaccgag gattttatgc atatcatctt tgctttgaac
    17401 cgcttcaacg agtccatcgt tagaaaaagc gatggctttt aataaaggtg aaagatcttt
    17461 gactgcctga tgatggtaag aattcacaaa atatggatcg gggagaaggt tgcttaacaa
    17521 actgtctgaa acaatcttga cttcgtgagt cgtaaattgc ggggcagtgg gctgttgttc
    17581 atgttttact gaccactttg gatataatga aagatcttga taaagtgtac cttccaaaac
    17641 gacattcaat agttggagtc cccggcagac tgcaaaaatt ggttttcttt gtttcaatgc
    17701 ttccaagatc agtgcctgtt caaattggtc tcgttgaata tttgtttccg ttagctttgg
    17761 atgaggatct tccatgtaaa gttgtggact gacatcttga ccacctgcaa gaataagttt
    17821 gtcgatttgt ccaatcagtt gaggagctga atctggagac atgactggca gaataagagg
    17881 caatccttga gcatctaaaa ctgcatccac gaatccttgc ggtgtatagc tcacttgatt
    17941 tccttggaaa gtatctgttg ctcgaatcag ttgatttccg gcaatgccga tgattggttt
    18001 catttgtatt ccccctaaag tagacttatt gtaacaagga tttaaaaaaa ttaaactatg
    18061 taagacttgc ccctatactt atctgttctt gctgtgttac tatctgtaaa gagaaatttc
    18121 gtgtgaaatt catgacgata gttgaaaata ttgcttaatt tgttataata aaaagtaagc
    18181 agaaataaaa aggttgggcg taagcttcaa ggatctagtt cttcaagggg tgagaaggac
    18241 attttattga aggggcctgc ctatactaag ttatctttag aggtacatac tttcaatgaa
    18301 aaaagaaagc atgtacctct tttttaaatc gaaaggaagt gaagcaagtg ttagaagctt
    18361 tggaacaaat ccgaaaagca gaagaagaaa atgaaaagcg tgctcaaaca ctgcggcagc
    18421 agctgaagat ctatgcaaca gaaaaagagc aggaattgga aacgatccaa acaaactatc
    18481 gacaacaact aaaacagttg gtggaagaaa aagaacaatt tgaaatacaa gaattagaaa
    18541 aagaaaaaat gaaattgaaa gcagaagcag acaaggtgca agcaactttg aaagatcaat
    18601 atcaaaagca tcagagtcaa gcgatcggtg cgatcattga aagggtgaaa gaaacttatg
    18661 gccgtcacta agatggaaaa agtgaccctc atttcagata aaagaaatca ggagaggatt
    18721 ttacaagcag tacaaggaat ccaaaacgtt gaaatccggg atctgtatca aaatagaaca
    18781 aacaaccagt gggtggagaa gtattttcca gataccacga ttattgataa agaagcaaaa
    18841 ttaagcgctt taggtaatcg gttgaaagac atccaagaag ctatccaatt catacaacac
    18901 cacggcgata gccgtcaaaa gaaactccat ttgaaacgtc aagaactttc cttacaagat
    18961 ttggaagcca attattccga agaaaatttc ataaataaat tgaaagaagt ccttgattta
    19021 aaagaaaagt gggaacaact aactgaagaa cgtgatcgtt tagaagaaga ggaagaatgg
    19081 cttcttcatt ggcaacagct ggatattgct ccaagtatgt atgcaagtaa gacgaccatt
    19141 tttgagatgg ggactgtgag tgcagcaaat tttgaaagtt tcaaggaaga actgagtaag
    19201 cttgatgacg tttatatgga agaaatagat tatacgccaa aacaagttta tctttcgtat
    19261 gttgctttaa aaaaatcagt tgctgttata gaagaaattg ctgggaaata cgggttcaat
    19321 aaagaaacgt atccttatga acaaaatcct aaagaaaaac tgcaagagac caagcagcaa
    19381 ttatccattg ttcacgagca gcaaaagaag ataacgacag cgttaggtca gtgcagtggc
    19441 tatatccaag aatttgaatg ggtagaagaa gtcacacttg ccgttgcaga acgagaaaaa
    19501 ataaaagaac ggtttatcca tgcgacttat ctgatcgttt tgcaaggttg ggtagatgca
    19561 gaagaaaaac agaatttgct gcatgtgtta aacgaaaccg tatcagaaga agatatatac
    19621 gtcagtttcg aaacaccaaa ctcagaagag attcagcagg aagtccctac taaattgaaa
    19681 aaccatccgc ttgtcgaacc ttttgaattg ctgactgaaa tgtacagtct gccaaaatat
    19741 gaagaagtag atccaacacc ttggatgaca ccattttatc ttgtcttctt cgggatgatg
    19801 gtcgcagatg ttggttatgg tttgctgatg ctcattggga caatactagc tcaaaaacta
    19861 cttgttctac cacgcgggat gaaacgtttc gtaaaattct ttgagattct ctcgatacca
    19921 tcgatcatct ggggattgat ctacagttca tttttcggac agtcattacc aaaagaactg
    19981 tttggcatcc gcttgccttt cccaatccta tctacgacgg atgacgtcaa tacgattttg
    20041 attttatccg tgattttcgg tctgatacag attttggttg gattatttgt ggcagcaaag
    20101 gaaaatatca ggagaaaaga ttacttgagt gctgtcagtg atggatttgc ctggcaaggg
    20161 atcctaattg ggatcgttat tgcgttggtt ggtgccatgt tgataaaaaa tacagcattt
    20221 gtttaccttg gcgctgggct atcgatcatt gctgccttat gtatcttgat cgttccgatt
    20281 atccaaacgc cgtctaaagt caaaggtgct gccaaaggtg cgtataatct ttacggactg
    20341 accggctata tcggtgattt agtcagttat acacgtttga tggcattggg tatttcaggc
    20401 ggaagtattg gagcggcatt caatatgcta gttgctttca tgccgccagc tgctcgattc
    20461 agtgtaggga tccttttgat catcgcttta cacgcactga atatgttttt gacactgcta
    20521 agtgcctatg tccatggcgc acgattgcag tatgtcgaat tttttgggaa gttttataca
    20581 ggaggcggac gtgcctttga tccgctgaaa acggcggaaa aatacgtcaa catcaatcac
    20641 aagaaaaaaa acaataaata attggaggat ttttatataa tgatggatta cttaattagt
    20701 caaaatggtg gaatggtatt tgcggtatta gcgatggcaa cagcgacgat tttttcaggg
    20761 atcggttcag ctaaaggtgt tggaatgaca ggtgaggcag cagcagcatt gacaacaagt
    20821 caacccgaaa aattcgggca ggctctgatt ctgcaattgc ttccaggcac gcaaggtttg
    20881 tatggattcg ttattgcctt tttgattttt atcaacttag gaaatgacat gtcagttgta
    20941 caaggactga actttctagg tgcttctctg ccgattgctt ttacaggctt gttttcaggt
    21001 attgcccaag gaaaagtcgc agcggcaggt attcaaattt tagcgaaaaa acctgaacat
    21061 gctacaaaag gaatcatttt tgctgcgatg gttgaaacat acgcgatttt aggtttcgtt
    21121 atttccttcc tattagtgtt gaatgcctaa gcataaagga ggaaaagcag atgaacgcca
    21181 ttgaaaaaat catctctcag atgaacgaag cagcagagca ggaaagagcg gcgttagaac
    21241 aagaagagcg aatgaagatc gatcaaaact ttgaacaaaa acgtacgcaa gttgaaacag
    21301 aacatcaaaa acaaaaagaa aaacaaatcg aattactcga aaaaaaatac cgtcagctaa
    21361 ggaatcgcca gcaagtagaa gtacgacaag aaaatttgaa tgcgaagcag gaatttttaa
    21421 gacgattgtt tgcagatgcg gtaactgaaa tggaaaattg ggatgaatct gaacaaatcc
    21481 agtttatcaa aaatgcattg tattcattac ctttgacagg aaaagtagca ttcattgctg
    21541 gagaaaaatc agcagcctat ctttctcaga cgttgttgga tgaatggaac aatgaacttc
    21601 cctttatgat ggttttaagt gatgaaactg ttgctgatca agcgggtttt ctgataaacg
    21661 atcaaggagt tcagtataat tttcttttca gcagccttgt acaagatatc caaggaacga
    21721 tgagttttga gattgccaat caattattcg aataaggagg gatcagtgta tggaatacca
    21781 cgaactaaat cccttgattc gcggaagaga gcttgaactt ttgtccaatg agacatttga
    21841 acggatgatt caaacaaatt ctgtcgaagc acttggtgaa atattgaaat ccacgattta
    21901 cagtccatat atttatgacg gatatgaata tgacttcgaa cagaatcttt taaaggagca
    21961 gagccgtcta tttcgctggt taaaggaatc agcaccggag cctgaaatcg tttggatcta
    22021 tacgatgcgt tatactttcc ataatctgaa ggttttgaca aaagctgaga tgacaaatca
    22081 aaatctggac catttgtata tcgacgatgg attttattca ttagaaacct tgaaggatgc
    22141 cattcatacg caagtttcaa atgaacttcc tgaaagcatt atggacagta tacgagaagt
    22201 acgtgattat tttgaagagt ctaccattct tcagggaatt gacgtgattt atgatcgaca
    22261 gtttttgaca gagcagcgac ggcttgccga taagctagga tatcaagaat tgctgacaga
    22321 agtcattgct tttattgact tgaccaatat cacaacgatg gctcgaggaa tattgcagaa
    22381 aagaacatat gggttcatga cgacggtact ttccagctcg ggaagtatcg aaaaagaagt
    22441 atttttgaac tttgtagata aagatatgga agattacacg aattttctat tagagacaga
    22501 ttatgctgat tttctgcgcc ctgtcatccg tgagggaaat attgatctcg taaagcttga
    22561 acagttgaaa gatgattatc taagttcatt gtatcaagaa gcacaaaccc aggctttcgg
    22621 accactgcca ctactagcct ttttgaacgc aaaagaggta gaaagcaaaa accttcgttt
    22681 actggttatc ggcaaaagaa gccatttcga atcagaaaca atcagaaagc gggtgagaca
    22741 agtctatgac gcataagatc ggtgtagttg gcgacaaaga ttctgttttg ccattcaaat
    22801 tgtttggctt tgatgttcgt tatggtacaa ccaagcaaac cgttcgtcag gcaattgaag
    22861 aaatggcaaa gaatgagtat ggcgtgattt atgtcacaga gcaatgtgca gcattgagcc
    22921 cagaaacgat cgaacgttac aaggaacaaa tgatacctgc tatcgtattg attcccaatc
    22981 atcaaggatc attagggata gggctggaag aaattcaaaa aaacgtagaa aaagcagtag
    23041 gtcaaaatat cttatagtat gaaaaggaga tagaaatttt gcaaattgga aaaatcataa
    23101 aagtctccgg acctcttgta atggctgaga acatgtctga tgccagtatc caagacatgt
    23161 gtctagtggg agatctagga gttatcggag aaattatcga gatgcgtggc gatgtggcgt
    23221 ctattcaagt atatgaagag acttctggaa ttggtccagg cgaaccggtt cgctctactg
    23281 gtgaagcttt atctgttgaa ttaggaccag ggatcatttc acaaatgttt gacggaatcc
    23341 aacggccatt agataccttt atggaaatca cacaaagtaa tttcttaggg cgcggagttc
    23401 aattgcccgc attggaccat gagaaaaaat ggtggttcga accaacagta gaagccggag
    23461 aaacggtgag tgctggagat gttatcggga tcgtagaaga aacaaaagtt ataaaacata
    23521 aaatcatggt gccaaatggg ataaaaggaa cgatcaaaac aatcgaaaaa ggttcattca
    23581 ctattgatga aacagtatgt gtcattgaaa ccgaaaatgg tgacaaaaat ttgacgatgc
    23641 ttcaaaaatg gccagtaaga cgtagtcggc caatcaaaga aaaattaaac ccggatgcac
    23701 ccatgatcac tggacagcga gtgattgata cattcttccc agtgacaaaa ggaggagcag
    23761 cagctgtacc tggtcctttt ggtgcaggga aaacagtcgt tcagcatcaa attgcaaaat
    23821 gggccgatgt ggacatggtt gtctatgtgg gatgtggcga gcgtggaaat gagatgacgg
    23881 atgttttaaa tgaattccct gaattgattg accctaatac aggagaatcg ttgatggaac
    23941 gtacggtatt gattgctaat acatcaaaca tgccagtagc agctcgagaa gcttctatct
    24001 atacgggaat cacaattgcg gaatatttcc gtgacatggg ttatgacgtt gctatcatgg
    24061 cagactccac ttcacgatgg gcagaagcac ttcgtgagat gagcggacgt ttggaagaaa
    24121 tgcctggtga tgaaggttat ccagcttatc ttggttcacg gcttgcggaa tactatgaac
    24181 gatctggaag agtcattgca ttaggatcag aaggtcgcga aggaagtata accgcaatca
    24241 gtgctgtatc cccgtctgga ggggatattt cggaaccagt cacacaaaat acattgcggg
    24301 tcgtaaaagt attctggggt cttgattcca gtttagccca aaaaagacat tttccttcga
    24361 tcgattggat acaaagctat tctctttatt caacagaagt agggaagtat atggatcata
    24421 tccttcaagc tgactgggca tccatggtca ccgagggcat gcgtattttg caggaagaac
    24481 agcagctgaa tgaaatcgtg cgtttggtag ggattgattc cctttcagat aatgaccgtc
    24541 tgacattaga agtggcaaaa tccattcgtg aagattattt gcagcaaaat gcttttgatg
    24601 atgtcgatac attcacttca agagagaaac aattcaaaat gttgaagatg atcttgacct
    24661 ttggtgaaga aggacgccgt gcgttgtcgt taggtgctta tttaagtgag atcatggacg
    24721 gtaccgtatc gattcgtgaa aggatcggac gaagcaaata tatcccggaa acagaattag
    24781 aaaaactaga tcaaattatt ggtgaaatca agcaaacgat gcaaacgatc gtttcagaag
    24841 gaggcatgag caatgattaa agaatatcgt acgatcggtg aagtcgtcgg tccattgatg
    24901 gcggttgaaa aagttgctgg tgtcaaatat gaagaattaa tcgaagtccg tatgcaaaat
    24961 ggcgagattc gtcgtggaca agtattggaa gtccaagaag ataaagcaat ggtccaaata
    25021 ttcgaaggaa caagtggtat caatttacgt gactcttctg tacgattttt aggccatcct
    25081 ttagaactag gtgtatcgga agacatgatc ggtcgagtat tcgatggttt gggacgaccg
    25141 aaagataacg gaccagagat cctgcctgaa aagcatttgg atattaacgg agaagtaatc
    25201 aatccagtag ctcgggatta tccagatgag tttatccaaa caggtatctc tgcaatcgat
    25261 catttgaata cattagttcg tgggcaaaaa ttaccagtat tttctggctc tggtcttcct
    25321 cataaagaat tagctgctca gatcgcgcga caagcaacgg tactcgattc atcagatgat
    25381 ttcgccgtag tctttgctgc tattggaatc acttttgaag aagctgaatt tttcatggaa
    25441 gattttcgtc aaacgggcgc aatcgaccgt tctgtcatgt ttatgaattt agcaaacgac
    25501 cctgcaatcg aacgtatcgc tactcctcgt atggctttga ctgctgcaga atatcttgct
    25561 tatgaaaagg gaatgcatgt tttggttatc atgacagaca tgaccaacta tgcagaggca
    25621 ttgcgagaga tttctgcagc acggcgagaa gttccaggaa gaagaggata tcctgggtat
    25681 ctttacacga acttagctac tttattcgaa cgagcaggaa gaatccgcgg actaaaagga
    25741 tcggttactc aaattccgat tctaacaatg ccagaagacg ataaaactca tccaatccct
    25801 gacttgactg gttatattac agaaggacag atcatcttga ctagagagct ttacaagagt
    25861 gggattcagc caccaattga tgtactcccg tctctttcgc ggttaaaaga taagggaact
    25921 ggacccggaa agacaagaga agaccatgca gctacgatga atcagctttt tgcagcctat
    25981 gcacaaggaa aacaggcaaa agaattagcc gtagttttag gtgaatctgc tttatctgat
    26041 gtagacaaga tctatgcgaa gtttgctgag cggtttgaaa aagaatatgt caatcaagga
    26101 ttctacacga accgttcgat tactgaaaca cttgatctag ggtgggaact gctatcgatg
    26161 ttgccaagaa ccgaattaaa acgaatcaaa gacgacatgc tggacaaata tctgccagaa
    26221 gggaagtgag ttctgatggc acgattgaat gtgaatccga cccgcatgga attgactcga
    26281 ttgaaaaaac agttgacaac tgccacaaga gggcataaat tattaaaaga taagcaagat
    26341 gaactgatgc gtcaattcat cctgttgatt cgaaagaaca accagctgcg tcaagaaatg
    26401 gaagagtcta tgacagaagc aatgtctgat tttgtattgg caaatgcttc gatcacggaa
    26461 cctttcatcg aagaattatt tgttttgccg gcggaaaacg ttgatttgtc tatcgtagac
    26521 aaaaatatca tgagtgtaaa agtacctgtg atgaattttg aatatgatga acagctgaca
    26581 gacacacctt tggaatacgg gtatttgaat tccagtgccg aactggatcg gtcaatcgat
    26641 cggtttacta ccctgcttcc aaaacttttg gaactgacag aaatcgaaaa aacttgtcaa
    26701 ctgatggcga gtgaaatcga aaagacacgt cggcgagtca atgcattaga atatatgacg
    26761 atccctcaat tagaagaaac gatctattat attcgtatga agctggaaga aaacgagcgc
    26821 gcagaagtaa caaggttgat caaagtaaaa aatatgggta ccactgacta agtggtatct
    26881 ttttttaaaa gaggaaaacg atgattaaac aaagcaaaca aataaagaaa cgtttgccgg
    26941 ctgttcagct tctcgcatta ggattttttc tcctgatttt agttggcggc ggcctactta
    27001 ccctaccatt ttttagtaat agtgggcatg ggacaaattt tatcgatgcg cttttcactg
    27061 caacttctgc tgtctgtgta acgggattga caacattgaa tacagcagag cattggaaca
    27121 gtgctggtca atttttgatc atgcttttga ttgagatcgg cggtcttggt tttatgatgg
    27181 ttccgattct atgctttgca ttgataaaga agaaagtcag tctcagcaca cgtattatat
    27241 taaaagaagc gctgaatcta gaagaagtat caggtgtgat gaagctcatg ctttacatcc
    27301 taaaattggc ctttgtgatc caattgattg gtacggttgc tttatctttt gtatttgtgc
    27361 ctgaatttgg ctggttgaaa ggtatctggt acagtttgtt ccatgcaatc tctagttttt
    27421 gtaatgcagg gtttgatttg ttaggagaca gtttagccaa tcaccagcaa aatgtttatt
    27481 tgatcatggt ggtatctgct ttgatcattt ctggtgggtt aggcttcatc gtatggcgtg
    27541 atttactgga atatcatcag aaaaagaaga tgacgattca ttcaaaaatc gcattaaccg
    27601 ttacaggtac ccttttatta ggcggattcg ttgtgttctt tttcacagag cgcaatgggg
    27661 caacgctagt ggaagggaat atgtttcaac gattggcaaa cacctttttt atgagtgtga
    27721 cacctagaac ggctggatat tattcagttg attacctcca tatgagccat gcaggtctga
    27781 ttttaacgat gtttttgatg tacatcggcg gaacatctgg gtcgacggcc ggcggattga
    27841 aaacaactac gttaggtgtg ttgctgatcc agatgcgttc gatgttgaaa ggacgtacga
    27901 gagcggaagc atttggccgt accatccgac aaggcgcagt gttgcgggca cttactttat
    27961 tttttgttac gttgacgttg tgtgtagtcg ccatcatgat tttatcggtg actgaaacga
    28021 tacctaaaac ttctggcatc gaatatattg cttttgaggt cttctctgcg tttggtacag
    28081 taggtcttac gatgggattg acgccagact tgactgcaat agggaaattg atcattatag
    28141 cgcttatgta cattggacga gttggtgtat tgactgtggt cttctctctg atgacaaaag
    28201 cacaaagaac acaatcaaaa tacaaatatc cagaagaaag tgtcatgatt ggataatttc
    28261 atcttctgac agaaacctag tgatttagta aaataagaaa ataaaataat ttttcttgct
    28321 tcttggatac tttaagtgca aaatgttcgt ttattttttg aggcactacc cgttgttgaa
    28381 cctcgggtag tgcctctttt ttattgaaag gaatcaataa gatttgattc ctttatttat
    28441 caataggtta taattcatat ttttttattt tttcttttac gatacttagt ccagaagcta
    28501 aaatttcaag gttattagag gatagggaaa ttcgaacgaa tgcatctggt tgcgcacgtg
    28561 tagtaaagcg tctggaatga taaagtcgga taccgttagc aagaaagtca ttctcaatta
    28621 tcttagggtc aatctcagga tcaactggaa gaattcgata gtaagggaca cgattcgttg
    28681 gtttttctac tttgaaaaga gaatcaaaaa gctgattggc tctttttgta agacttaatt
    28741 tagtttctaa gatcctattt gcttcatttg aatggaggat ttgagtgatg acttccacat
    28801 ctaatccaga agttttcaca tttatattaa aaattgcttg ttctatcttg ctttggacat
    28861 gtactggaac tacaagataa gcaactcgca atccagaaca aataaatttt gtcattccag
    28921 ctaagtagat tgtttggtta ggtaataaat tttggaaagg aggaatgatc gtatgttgat
    28981 agtaagttgt taaaaatgaa tggatatcat cttcaataac ccatagacct tctttttcaa
    29041 tcacttcggc taattgctct cgtcttttgt gagagatttg aaaccctata ggattattac
    29101 aagaaggcat aagaaagaca ccatgaatct tcttttttct acattcctga atcaatatat
    29161 caggtcgcat tccttgctcg tcaaaatcaa ttggaacgat ctctaaatga tataactgag
    29221 ccaattcaat gaaattagcg tatgtatatc ggtctgttgc tattctatca cctggagaga
    29281 aaagtgcaga aagtgtgata gccaatccat tttgaacacc ggaaacaata gatagagatt
    29341 ctaaggacgg aatgactcct tgagttttta accaatttgc tgcagtagtc aattgaaaat
    29401 ttgtgccttt gggatcttgg taattaagca aaccaacaag atttgggtta ttactagttg
    29461 attgaataaa cgggacaacg aatttattac attcttcaaa agaactaacc agaccaaaat
    29521 caatgatatg ttcggttact tcattggtag agatggtgat ggactcaaag acattgggag
    29581 aaataaatgt gccacttcca atattcgtat acagcaaacc tttctcaatt ccatatttat
    29641 aagccttgcc aacggtagta aaatttaaat ctaaataatc agctagctct ctttgggagg
    29701 gtaactgagt gtttttctgt aatttattct ttaaaatatc ttgttctaat tgttgaatca
    29761 acgatcgata ataaggacgc ttcaattttt gtttgtctgg tcgccaagtt aacgggtaat
    29821 tgtcataaga attaataggc attttctcca ctccttaaaa ttgtatacca tacaatttta
    29881 ccattgattg tattgatttt agaagttaat cttttgtgag gagggaattg tctatgaaaa
    29941 ttattaattt tgaggaagta gtagcttctt ttagttttga agaagcgatt caagtaatga
    30001 aaaaatgttt ttttgattat gaaagtggta aaatcagcca aaatcctcga ttggtggaaa
    30061 ttttacctga cggaaaaggc aaaaatatgt ttgcgatgat gcctgcttat ttgggggaga
    30121 acagatattt tggcacaaaa gtcattaccg cttttccgga taatcatcag tatcatttac
    30181 cttctcattt aggagagatt ttcttgtttg atgctcaaaa cggactaccc aaagcattga
    30241 taaacgcaaa tgcagtcacc tggattcgaa cagctgctgt atctgcgctg gcaacagatt
    30301 acttagcaaa tccgcatgca gaaacacttg ctttaattgg agctggtcaa caagcattgt
    30361 cgcatttgac tgcgatttct accattcgtc ccatcactac agtgtttgtt tacgatattt
    30421 tagaagaaag acgaaatact tttatcgcta aagctaaaaa acagtatcct aaaataacgt
    30481 ttataaatgc aatatcagta gaagatgcag tacgtccagc ggaaatcatt tgtacgttga
    30541 cctctagtaa agaggcattt cttcaaaaag agtgggtaag ggaagacgca catatcaatg
    30601 ctgtgggcac atttactcct gatacaagag agataagtac atcgttgatg gaaacttctc
    30661 aaatctatgt agatgattac tcagctgcct taacagaaag cggggacctg cttatagcca
    30721 tggcagaagg agatttagag gaatcttgta ttgttggtac attaggcgaa ttagtttctg
    30781 agaaaaaaac attttataaa ggagaatcga ggccgacgat tttcgacgca gttggtctag
    30841 ctattgaaga tctttgttgt gcagaatata tttataacaa attagagaaa ggggctttaa
    30901 aatgaactta gattattacg tagttgatgc atttgcagat gaggtgttca aaggaaatcc
    30961 agcagcggtt tatgtgctag aagaatggct gccagaaggt acgatgcaaa aaattgccat
    31021 tgaaaacaat ttatctgaaa cagcatttac agtgaagaaa aaccaagaat ttgagcttag
    31081 atggtttacg ccagatcgag aaatcgatct ttgtggtcac gcgacattag caacagcatt
    31141 tgttttattt aactattaca aaatacctga tgaaacgatt aaattttcta ctcaaagcgg
    31201 taatctattt gtgacaagaa ttaaagatta ttattacatg gattttccta gtattatgcc
    31261 gaaaaaagtg ccgatattgt ctgaatatga agaagcgatt ggggctaaga ttaaagaagc
    31321 ctacttagca cgtgatttat ttttcgtatt agaagatgaa aaaacggtgg ctaaattgca
    31381 gccagatttt acagctatca aaaattttga attaggaata ggagtcatcg tgacagcaga
    31441 aagtgtgcaa aaagactttg tttctagaac cttctttcca aaattaacaa tcaatgaaga
    31501 tccagtatgt ggatcagcac attctaatct tattccttat tgggcagaaa gaatgaataa
    31561 aacaaaattg tcagcttatc aaatgtcatc aaggggcggg gatctagaat gtgaattaaa
    31621 agaagatcgt gtgataatag gaggaaaagc agttttgttt tctaaaggta cctcgtttat
    31681 ttgatttctt tcaaatgaat taaaaataaa ttggtggaga gtggcaacct tatagctaca
    31741 atggttgtta aaaaaagacg caaacttttt caatttaatg aaaagtttgc gtctcatttt
    31801 aattattggt gtttgttttt tattcaatca agagtaaaat gccccatact aactatcctc
    31861 ggatgacttc gattttataa ccatcagggt caatgacaaa gtagtaagaa ggcgcagtgc
    31921 caggtaatcc ttttaagtca gtaatctcaa gaccagcagc tttatgttgc tcgtgtaatt
    31981 tttctagatc atcagctgct atagcgatat gaccatagcc gtctcctaga tcatacgcac
    32041 catgatcata gttgtaagtc aactctaatt catagtcatc cccaggaagt gtcaaataaa
    32101 caagtgtaaa tttgttttct ggaaaatcac ggcggcggct ttcttcaaaa ccaaatgcct
    32161 tttgataaaa ttcgattgat gcttcaagat ctttcactcg aacacatgtg tgagccattt
    32221 tcatagattc atctctcctt ttccttttac tcaatcataa caaaaagaag taaggaaata
    32281 gttgatttgt gcttgttcat gagaaatttc tcatgtaaaa tggatagaaa ataaaactgt
    32341 taaggtggaa actattcatg gataaaccaa tttttggtga aaaaaagcaa tttgctgatt
    32401 atcaaacccg ttatgcagca tatattgtca tagaaagaga tcagcagatt gcagtaatcg
    32461 aggctccaaa tggtgctttt tttcttcctg gcggggaaat tgaaggagaa gagacgaaag
    32521 aagaagcgat tgtccgtgag ctgatagaag aaatgggaat tgtggcagaa atttcttctt
    32581 atctgggaga agctgatgag tatttttact cgaattatcg tgcaacttat tattataatc
    32641 caggatattt ctttgttgct gattcttgga agcgtatagg agaaccaact gaaaagacca
    32701 ataaaatttg gtgggtgagc cctcaagaag cgcttgtgaa attgaaacgt ggtagccacc
    32761 gatgggcagt cgagagatgg atcgaaaaaa ataaaaactg aaagaaagcg agtagatcag
    32821 ctttctctca gtttttttat ttattacagt acatattttt tgattgcttc agctacaccg
    32881 tgctcgtcgt ttgatgaagt gatgacattt gctgcttctt tgacaagaga aacggcattt
    32941 cccattgcta ctcctagacc agcatattca atcatggata agtcgttctc gttatctccg
    33001 atagccatga tttcatcttg atcaatacca aggtgctgtg cgagattcgc aactgccgca
    33061 cctttacttg cttctttatt tagtacttcg aagtaatagg gcgcactttt gaccgttgtg
    33121 tatttatcac ggaaagtttg cggtaaacgc gcaattgctg catctaaaat ttctggttcg
    33181 tcgatcatca tcattttgac gatgttcatg tctggtgtca tttcttcagg tgttcgatat
    33241 tttagcggca tcttgactaa acttgcttcg tggatcgtat aagcgctgat atctcgatta
    33301 ggcgtgtaga tcgctttgtc atcgatcgaa tggagatgac tgccgacacg gcgtgccatt
    33361 acttcgatct ctaggaaatc ttcatgtgtc agtccgtgac gggcgatgat tttacctgat
    33421 ttcgtttgtt gtacgagtgc cccgttataa gtaataacgt aatcattatc ttgaaaaagg
    33481 ttcaactcgt ttaactgttc ctggacacct ggtaagggac ggccagtgca taaaacgatc
    33541 gaaacacctt ttgcaacagc agcggcaatc gcttctttta cttcttttgt tacttctctt
    33601 ttctcattta ataaagtacc atcgatgtcg atagcgacta gtttgataga cataatttcc
    33661 tccaatatat tttaatttat ttcaatcaat gcgccattac ggatatggct ggcaaattct
    33721 tgataagttt cgtcaaataa atcataatga tcacgcaagg acggatcaac catttctttt
    33781 ggaaagaaaa atcgctcatc tccttgttct tgtcccgcta atgcagcaac aagctgacta
    33841 acctgtgata attctatcaa agttccgtca tttcgcaaaa tctcgatttg tgtgcgatgt
    33901 ctgccttgtt ctgggcgata aaaatcataa ggtagatcgt agctagaatt cacagcagtg
    33961 taataaacag gattatatcc gaccttttct actaacaaag tgagttcttg gactaatttt
    34021 gaatcccggt tgccagaaaa agtagcagat ttcagtggtt tacgattcaa aaaacgttta
    34081 gctaaatcat ttaaaatagg atcagcagat tcagaccatt gagtaaagta agtgcccaag
    34141 accccatcat caagtttgag gtattcttct aaagtaaagc ttccgtcaag aaatggcaga
    34201 agtaattgag aatggagttc aaaactgctg gcatcttctt gatacaactc gtgtgcgcga
    34261 tgaagcagat gctccaaaat tacttccata ccacgggaaa caggatggaa gtacacttgc
    34321 acatacattt gatatcggct aacgatataa tcttccactg catgcatgcc actcatggaa
    34381 aaagcgatcc cgccttcata aggacgaatc acacgtaata ttcgggtaag atcaaatgtt
    34441 ccatattctg ttccagtgaa ataagcatcc cgaagcaaat agtccattcg atctgcatcg
    34501 atctgactag aaatcatttg gacaacttgt gggttggggt aagttttttg gatcacacta
    34561 gctacctttt caggaaaacc ttcttctact cggttaagaa tctgatacac ttctgtttct
    34621 ggagaagtga tgatctctac agtgatggct tcatgattcg tatggaagat atattcaaat
    34681 gtatgagagt aaggaccatg accgacatca tgcaacagtg ccgcacataa agtcaccagc
    34741 cgttcctgat catcccagcc tccgttgcct attttttctt ttgaaaaatt tcgagaaaag
    34801 atatcgcaga ttcgtcttga aatctcataa acgcctaatg aatgagtaaa acggctatgt
    34861 tctgctccgt gaaaagtgaa agaagaagtg cctaattgtt taatgcgtcg tagacgttgg
    34921 acttctttcg aattgatcaa atctaagatt acttgatgct ggacatggat atagttatgg
    34981 actggatcac gaaaaacttt ttccataggc agcatttgat atttataagg ggttgtcata
    35041 atgtagctcc tttatgttat tacgttgttc cattctctgg atttggttgt tccattgctc
    35101 cagctggatt tcttttttta gccagtcggt agaatcctgt aaatcacttg cagaatacag
    35161 cttttcaaaa gcttttgcaa atgcttcttt gacttctttt acaaaaaggg gttggtcaag
    35221 cagttcttca agtgttgcca ttgtagcagg atccactgca ggatagccat ttgtaccaaa
    35281 gtcttctttt aaagcagatt gataaaatcg cttcatgact tgcccacgtt tttcctgatt
    35341 accgttgaca cttaagtaca tcataacaga aatcccattt ttgatccgac gctgagcgat
    35401 accggcaaat tttttgccat ggatgcttaa atcataagtt ccaggacaat aagaatgggt
    35461 gatttcgaat gcttgtatcg gtgcctttgg aaaagcgtat ttagtcaata ggagcatttg
    35521 ctcgtaagcg tcatctatgg ttattttttt tgtgtcactt tgggggaaaa tcaaagaaat
    35581 attcaaaatt ccttcatctg atacgatccc taatccacct gaatttctga tcactggagc
    35641 gtaacctgca tcttccagtg tttggatccc gtcacttaga aaaggagttc gaacatcctt
    35701 catacctaag atgactgtgc agtcatattg ccagaaatgt aaaaagattt gctggtgttc
    35761 tttagaatat tccgttaata tatctgttaa tgcaaaaggg gaaaagtcgt ttttttgata
    35821 aatgtgctga tctagtcgaa tcgcagggtt cattcaaccg gctcctttgt ataaattcat
    35881 attttctaca atattatact ctaaaatcaa agagttgttt tggaaaaaag gttttctgta
    35941 aaaatggaca agttggttga caaaacaaaa gaaactagga acaatgtagc tatgagaagt
    36001 aaaggagaat gaataatgga attatcacaa ggaacaccga tttcaatcaa attgcgtaca
    36061 aaagtaaaac agcaagggga agtgcaagat ttttattttg atttgaaagg gcaaatggtg
    36121 acaattggcg atacgctgta catacgttat aaagagattc aggaggagac gggcgatgag
    36181 attcctgtaa cgatcaaatt agttccagat ggtcatgtac agctgatccg tgcaggagaa
    36241 atgcggatgc gtttgaaatt tggctataaa gaacggttag aaacatccta tcgaacacca
    36301 tacggtatga tccagattgc tacttttacg aaagaactgc atgttagttt gaaagaccgt
    36361 cccacagcag ggaaggttcg aatcgattat gatctgttca tgggaccgga aaaaatcggc
    36421 gaatattatt tgaccttgga ttttacagcg taaatataaa agaaaagttt gattttttgt
    36481 gtctgatttt gtatgataag gagtagactg tgaaaggacg tgtcctgatt ggaaattagt
    36541 gtatttgaag gtgcaaacaa aagcgaatta tcaatgatcg aagtagcaca cgcgatctta
    36601 gaacaacgtg gcgatgtcat ggatttttct gatttagcta accagatcca aaactatctt
    36661 gggaaatcag acagtgaaat tcgtgattca ctcgcacaat tttatactga cttgaatatt
    36721 gacggcagct ttatctcatt aggggataat cgttggggct tgcgttcatg gtatgctatc
    36781 gattcgatcg atgaagaagt aaaccatgga atggacgaag aggatgaaga tactccacgt
    36841 cgccgtaaac gcaagaaagt caacgccttt atcaatgatg atgaagacgc gatcgattac
    36901 aatgacgatg acccagaaga tacagatctg acagaagaag atgacgatga tctgtttgat
    36961 gacgatgatg atgaagatga agaaatcgct gcttataatt ctgacttgca agaaatcgga
    37021 gcagatgacc cgacagatga tgaagaagac ttgccaggaa atatcgaaga agatttaagt
    37081 atcatagacg aagacgatga tgatgaagat tatgaagagg aagaattttc tgactctgaa
    37141 aaagaataaa cattattttc ttacgagagg ttgtgacaga gacgatcagc ctatcagaat
    37201 aaggaggtgt gacacgattt ttgtcacacc ttcttttttg tatataaaaa tcccaagtaa
    37261 atacataaaa aataaaaaaa ttgaaacttt tagcgcacct tgtacgtcat attaagtgag
    37321 gcagaaagga gtggagaatg atttttactg gatataagaa aaaacggcag atcgaaaaat
    37381 accgtcacct gctgaatgga ctcatcgaaa ctgattatca aaaaatgttc cgtatcacga
    37441 tgaattacgt acatgataaa gaagaggcct tagatgtgat gcaagatagt tttcataaag
    37501 ccctgaacta ttttgaaaaa gaaaaagaga tcgagcattt tagtgcatgg ttttatcgga
    37561 tattgatccg cacggcatta gatagttggc gcagacaaaa aaggacgcct gtggacttat
    37621 ttgaaattca agatatcccc caacagttac ctttagaaac ttccgttgca gagctccata
    37681 tgattttaga taaaatagac agtccggaaa aagagattct gatcctctac ttttttgaag
    37741 gatttcgttt gaaagaaatt gcgactatct tggatatgaa tgaaaacaca gttaaaacga
    37801 aaatgtaccg ctcattgaat gctttacgtc aaatcctaga atgaaggaga gaagagtgcc
    37861 atgtattccc aaaaagaaaa tttaaaaaaa ctaaagaaaa cttataaaga acaagcaatt
    37921 cccaaagggc ttaaagagga gatccgccag cgttttatta tcgaagagca atcatttata
    37981 aaagcaaagc ggagaaagag acgtctccaa gggttcggag tatctttggc tatcgtaatg
    38041 attacaacaa gtagccttct ttttaatagt caagttcgaa gctttgcaga agatttaccc
    38101 atcttaggat cagtcattga attgatctta ggcgaacgct ttactgatcg atctgaaaaa
    38161 atcgatattc aggtaccgaa gatcaataca caaaatgaga aagaaaataa aacaattcat
    38221 ggattaaatc aaaaatactt tcgcgaagga caagcagatt ttgaaaaagc tgaaaaagaa
    38281 tatggaaatt ttgaaacgga tcattaccaa gttttgggag attatcagaa aatcgtagac
    38341 gataaccggt ttctcgtgat tgaaaggcag atcacccaaa cagcagcaga tagccatgtt
    38401 gaaaaaagat acgacacaat cgacaagaaa aacagtgtcc agctctcact tccactttta
    38461 ttcaaagatg acacctatct atctgttttg acaaaagaag tcaaacggca gatggccgaa
    38521 caagtcaagg aagatccatc taagtactat tggactgagc aagatattca agaagggacg
    38581 atagaaaaac caacacttgt tacgcctaca cgaagttttt atttgaacaa agagcatcaa
    38641 ttagttttga ctttttctca atacgaaatt gctcctggtt atatgggtac accagaattt
    38701 gtcattccta agtccgtgac aaaaacgatt ttggcatcgg aagattattt ggatcattag
    38761 acgagaagta gttgcgacta gcagtttcaa ttttcaagta agtacaagta aataataaga
    38821 agagaaaaag agaaagaaga gatatagtga aaagaaatta tttagttatc agtattattg
    38881 ctttatccgt gcttttgttt ttcgaaatta cttcggtggc ctccttgatc accgaagtaa
    38941 aaggacaaac acactcttcg gagcattcgt cacaatcttt caaacaatca gaacaatcaa
    39001 ccattaaaag ccaatcaact gaaacagcta acgtcaaaga agccattcaa gaatcagcgg
    39061 aaaaggtaca aagtcagtca tcacaatcaa cacaagacag tacaaaaacg agccgagatc
    39121 cggctgtcaa aagcgtcgca atcagctttg atgatggacc aggagcgacc acaacaccgc
    39181 agcttctgcg aatcttaaaa gaaaaaaacg tgcatgccac ttttttcgtc ttaggagaaa
    39241 atacggcgca gcatcctgaa atcgtgaagc agacagctga agcagggcac gagattggca
    39301 atcacacata cgatcatcag aatctggcca ctctttctgc ccagtcgatg acggaggaag
    39361 tgacgaaagc agacactgag atcaaaaaag tcactggcaa aacccccact tttgttcgtc
    39421 cgccctatgg ttctgtcacg aatgtaggag caacgatcat ccagcgaccg atcatcgaat
    39481 ggtctgttga ttcagaagat tggaagacaa gaaatcctga tttgattttg cagaagatcc
    39541 aagcaacagt atacgatggg gcaattattt tattccatga tatctatcct gaaacgattc
    39601 gtgccgttcc tcaagtgatc gattatctga aagagcaagg gtatcgcatc acgacagttg
    39661 gggatttatt agggcatcca acggctgtcg agaactatta tggcagaaac gatcatcggc
    39721 cagttcagta agtgagacaa gtatctttaa taaataacac attttaataa gtagttgaac
    39781 acataactac cttacttgca aaggcttaac aatatctata caggtacaac aaaaaactgt
    39841 ccaccaattt tctttggcgg acagttttca cttaaaaata aagaagcaac tattcgtaaa
    39901 ttatgctaaa atagcagtag aacgcgtcct gagggaatcg aacccccgtc tcaagaaccg
    39961 gaatcttacg tgatatccac tacactaagg acgcaagcac tgggataatt gtaactaaac
    40021 agataaaaaa ttacaagggg attggacaaa aaaatgaaat ttgagcaaaa tttttcacaa
    40081 aaacagcagc agacacagaa actagccatg acgcaacagt tgcaacagtc catccaagtt
    40141 ttacaatata acagtgagga gctgttggca ttcgttgaga atcaagcaat ggaaaatcca
    40201 ttggtggaag ttgttgagcc ggaatggcag ccagattaca taaaagcttc ttcatcttct
    40261 tatgaaggag aagagacaaa ttacctaaat cagattcctg atacaaaagg gtctttattt
    40321 gattcattga tcgaacaagt ccatttgaat taccgagata cttttttgag gaaaatcgtt
    40381 ctttatcttg tagaatacat cgatttgaac ggatttttga cgattagttt agaagaagcc
    40441 ggaaaagaga ttggagctac gcctatccaa atgctcgatg cgttgactct gattcagcaa
    40501 ttagaaccag ctggagtagg tgcacgtagt ttgcaagaat gtctcatgct tcaaacagaa
    40561 cgagatgatt atgcgccgga attagcttat atcgtgttgg aagaatgttt tgaggaactg
    40621 gtggagcgaa aatggaaaga aatcgcacaa cgtttttctg ttgatctaca tgctgttcag
    40681 cagatattcg actatttaca aacgttgagt ccaagccctg gccggatttt cgaccgtagc
    40741 agcgaattgt acattattcc tgatgtccgg gtattagtgg acgacgataa aaatgtacaa
    40801 gttatctcaa accgaaaaaa tcagccaaat atacgctttc aagagagtta cttcaaacaa
    40861 atgtcacaac aagcagataa agaaactgaa aattatttaa aagaacggaa acaggaattc
    40921 gaatggttga agaaaacgat cctacaacgt ggggatacaa ttttgcgggt tgctcaagtc
    40981 attgtttccc ggcaaaaagc tttctttatc gacaaggaac gtccaatcaa gcctcttacg
    41041 ttaaaggaag ttgcaactga gatagatgtg catgaatcca cggtcagtcg tgcagtcaac
    41101 gggaaatatt tggaaacaga cttcggtgta tttgaattaa aaaaattttt cactacacga
    41161 attcctacga atagtacaga acagacagaa gacctttcag cagatacagc gaagaaaaag
    41221 ctgcaggaat tagtcgatca agaagacaaa aacaagccgt tgtctgacca gaaattggtt
    41281 gaattgctga aaaaagatga gatagcgatc tcaagacgaa cagtagcaaa atatcgtgat
    41341 ttattaggaa tcccgagttc atcaaaaaga aaacgttatg ataactaatc agtcaaaaga
    41401 ctagaaaaag tatttcactt tttctagtct ttttagttga aaaacgagag caaaactgtt
    41461 agacttacag tcgtgaggtt gagatttccc tttattgatg tgaaattcga atagttaatt
    41521 tcttttttta tcgtatatgg gtcgttttaa gtctacattg gacgtaaagt gtccaactaa
    41581 ggagatcgct atgctggatg aaataaaaat gattgaatct gttgcaccag atattatcga
    41641 agtgttgcaa gaacgctata aaattttacg aaatatctat tggatgcagc cgattggacg
    41701 tcgaagttta tcggaaagta tggggatcac agaacgagta ttgcgaacag aaacagatct
    41761 tttgaaaaat ctgaatttga tcgacacctc aaaaagcggt atgacgctga caactaaggg
    41821 cgaagaagtt tatcaaagcc ttgaaaactt catggatcag cttttaggta cgcatcaaac
    41881 cgaacaacag ttggcagaat attttggtaa ccaacgctgt atcgttgttt caggaaacag
    41941 cgaagagcag accaaagtgg ctgatgcatt cggcgaagcg ctgagcgaag ccctagaccg
    42001 actacttcca gaaggcgaga atatcatcgc tgtgatggga ggaactacta tggctgtggt
    42061 agccgaacaa ttgtctaatc tggaaaataa gaaacggcat aacctgtttg tccctgcaag
    42121 aggcgggatt ggtgaagcga taactgtaca ggcaaattct gtcagtgcaa gaatggctgc
    42181 taaagcaaac ggtaaccacc gtgcacttta tgttccggaa caattaagtc tggcaactta
    42241 caattcttta ctcaatgagc catctatcca agaagtctta aacttgatta gtgaagcgaa
    42301 ttgtgttatt catagtattg ggcgtgcatt acacatggca gcacgtcgta agatgactga
    42361 aaaagaatta gtcatgctga aacaagcaaa tgctgttgcg gaatcttttg gctacttttt
    42421 caatgaaaaa ggtgaagtcg tttataaggt ccctagaatc ggcatagaat tgcaagattt
    42481 ggaaaaagtc ccgatcatca tggcaatcgc gggcggaaaa tcaaaagcca aagcaattcg
    42541 agcttatatg aaaaatgcac caaaacaaac gtggctcatc actgatgaag ctgctgcaaa
    42601 tgagatttta aaaggggtaa ccctttaaaa taaatatttt tttgattttc ataaggagga
    42661 aatcttaaat gacagttaaa gtaggtatta atggttttgg acgtattgga cgtctagcat
    42721 tccgtcgtat ccaagatgta gatggaatcg aagtagtagc aatcaacgac ttgacagatg
    42781 ctaaaatgtt ggcacacttg ttaaaatacg acacaactca aggacgtttc aacggaacag
    42841 ttgaagttca tgaaggttca ttcaacgtaa acggaaaaga agttaaagta ttagctaacc
    42901 gcaacccaga agaattacca tggggcgaac taggcgtaga tatcgttcta gaatgtactg
    42961 gtttcttcac ttctaaatca gcagctgaaa aacatttaac agctggtgct aaacgcgttg
    43021 ttatctctgc tcctggcgga aacgatgttc caacaatcgt ttataacaca aaccacgaaa
    43081 cattaactgg taaagaaaca gttatctcag gtgcttcatg tactactaac tgtttagctc
    43141 ctatggctaa aacattgaac gacaaatttg gtgttgttga aggattaatg acaactatcc
    43201 acgcttacac aggtgaccaa atgactctag acggacctca tcctaaaggt gacttccgcc
    43261 gtgcacgcgc tgctgctgca aacatcgttc ctaactcaac aggtgctgct aaagctatcg
    43321 gtttagtaat tcctgaattg aacggtaaat tagacggagc tgctcaacgt gttcctgtac
    43381 caacaggttc attaacagaa ttagtaacag ttcttgaaaa agaagtaact gttgacgaaa
    43441 tcaatgcagc aatgaaagaa gcttcaaacg aatcttacgg atacaacaca gacgaaatcg
    43501 tttcttcaga tatcgttggt atgacttacg gttcattatt tgatgctaca caaactaaag
    43561 taatgacagt tggcgacaaa caattagtta aaactgttgc ttggtacgac aacgaaatgt
    43621 catacactgc acaattagta cgtactttag aatacttcgc taacttataa gatagacaaa
    43681 cgtacaagtg taaattatag acatgtacat ttaaaagcgg ggaagcaatc gcgcttcttc
    43741 cgcttttttt gataataagt ttattcagga ggaaataaaa tggctaagaa aacagtgaaa
    43801 gatatcgatt taaaagacaa aaaagttctt gtccgtgttg acttcaacgt tcctttgaaa
    43861 gacggcgtga tcactgacga cactcgtatc aaagcagcat tgccaacaat caactacgtt
    43921 ctagaacaag gcggaaaagc aatccttttc tctcaccttg gacgtgtaaa aacagaagaa
    43981 gataaagaag gaaaatcttt agctccagtt gcaaaacgtc taggcgaatt attaggtaaa
    44041 gaagtaacat tcgtacctga aactcgcgga gaacaattag aagaagcaat ccgcaacatg
    44101 aatgacggcg acgttgtcgt attcgaaaat acacgatttg aagatattga cggtaaaaaa
    44161 gaaagcaaaa atgatacaga actaggtaaa tactgggctt cattaggcga tgtatttgtt
    44221 aacgatgctt tcggtacagc tcaccgtgca catgcttcta acgtaggtat cgcttcaact
    44281 ggtatcccaa cagttgctgg attcttgatg gaaaaagaaa tcaagttcat cggtgaagca
    44341 gtagaagaac caaaacgacc aatgattgca atccttggtg gcgcaaaagt ttctgataaa
    44401 atcggcgtaa tcgaaaactt gattcctaaa gcagataaaa tcttgatcgg tggcggaatg
    44461 acttacacat tctacgaagc aaaaggaatc aagatcggta actctctagt agaagctgat
    44521 aaagtggaac tagcaaaaga attaatcgaa aaagcaggcg acaaacttgt cttgccaatc
    44581 gacaatgtct gtgcaccaga attttcaaat gatgttgaaa cacaagtaat cgaaggagac
    44641 attcctgatg gtttgatggc tttagacatc ggcccagcat cagtaaaatt atttgctgat
    44701 acattacaag gtgcaaaaac agttgtttgg aacggaccta tgggtgtatt tgaaatgagt
    44761 aactttgcta aaggtacaat cggtgtttgt gaagcaatcg ctaacttaga aggcgcaaca
    44821 acaatcatcg gtggcggaga ctcagccgca gcagcagaac aattaggatt tgctgacaaa
    44881 ttcacacaca tctcaacagg tggcggcgca agcttggaat tgcttgaagg taaagaatta
    44941 ccaggactag cagcaatcaa cgataaataa acgaccaagt ttgctcaatt ctgacgagta
    45001 atcgatcaaa aggtgaaggg agttttcatg actccctagc catttttcaa taaattaagg
    45061 agtgtgttcc tcaatgcgta aacctattat cgcaggtaac tggaaaatga acaaaactgc
    45121 atcagaagca aaagaatttg ctgaagcagt aaaaaacaaa atcccttcaa atgacaaagt
    45181 tgattcagtc atcggatctc ctgcattatt cttacaagaa ttaatgacat cagctgaagg
    45241 tacagaacta aaaatctcag cacaaaactg ctactgggaa aactcaggtg cgttcactgg
    45301 tgaaacttca ccagcagctc ttgctgatct aggtgttcat tatgtgatca tcggacattc
    45361 agaacgtcgt gaatatttcc atgaaacaga cgaagacatc aataaaaaag cgaaagctat
    45421 ctttgcaaat ggtatgacac caatcctatg ctgtggcgaa tctttagaaa cctatgaagc
    45481 aggcaaaact gctgaatgga tcgaaggaca aattacagct ggtttagctg atctttcagc
    45541 tgaacaagtg tcaaacatgg ttattgctta tgaaccaatc tgggcaatcg gtactggtaa
    45601 atcagctgac gcacaaatcg ctgacgaaat ttgtggagtt gtacgtcaaa cagttgaaaa
    45661 actttatgga aaagaagtat cagaagcagt tcgtatccaa tacggcggtt ctgtaaaacc
    45721 agaaaatatt gctgaataca tggcaaaaga aaatgttgac ggtgctttag tcggtggcgc
    45781 aagcttgcaa gcagattcat tcttgtcatt gttagacgct gtaaaataat tgttgaaaat
    45841 ttgcgaaaaa tgcaagaaat gtttgcacta atgagcaaaa ttaactaaaa tcgtatatga
    45901 gggaaatccc ttaggaaaaa acaaactcaa aggagagaca aaacatgtca attattactg
    45961 atgtttacgc tcgcgagatc ttagactcac gtggtaaccc aacaatcgaa gtagaagtat
    46021 acacagaaag cggagctttt ggccgcggaa tggttccttc aggtgcttca actggtgaat
    46081 acgaagcagt tgaattacgt gacggagaca aagctcgtta tggcggtaaa ggtgtaacta
    46141 aagctgtcga caacgtaaac aacatcattg ctgaagcaat cattggctac gatgttcgtg
    46201 accaaatggc tatcgacaaa gctatgatcg ctttagacgg aactcctaac aaaggtaaat
    46261 taggtgcgaa cgctatttta ggtgtttcta tcgctgttgc acgtgcagct gctgactacc
    46321 tagaagtacc tttataccac tacctaggcg gattcaacac aaaagtattg ccaacaccaa
    46381 tgatgaacat catcaacggc ggatcacatg ctgataactc aatcgacttc caagaattca
    46441 tgatcatgcc tgttggcgct ccaacattca aagaagctct acgtatgggt gctgaagtat
    46501 tccacgcatt agcttcaatc ttgaaagctc gcggattagc aacttctgtt ggtgacgaag
    46561 gtggatttgc tccaaacctt ggttcaaacg aagaaggttt tgaagtaatc atcgaagcaa
    46621 tcgaaaaagc tggctatgta cctggtaaag acgttgttct tgctatggat gctgcttctt
    46681 cagaattcta cgacaaagaa aaaggtgttt acgtactagc tgattcaggc gaaggcgaaa
    46741 aaacaactga cgaaatgatc aaattctacg aagaattagt ttctaaatat ccaatcatct
    46801 caatcgaaga cggattagac gaaaacgact gggacggatt caagaaatta actgacgtat
    46861 taggcgacaa agttcaatta gttggtgacg acttgttcgt aacaaacact caaaaattat
    46921 ctgaaggtat cgaaaaagga attgctaact caatccttat caaagtgaac caaatcggta
    46981 cattaacaga aactttcgaa gctatcgaaa tggctaaaga agctggctac acagcagttg
    47041 tatctcaccg ttctggtgaa acagaagatt caacaatctc tgatatcgct gttgcaacaa
    47101 acgctggcca aatcaaaact ggttctctat cacgtactga ccgtattgct aaatacaacc
    47161 aattactacg tatcgaagac caacttggtg aagttgcaga atacaaaggt ttgaaatctt
    47221 tctacaactt aaaaaacaaa taattctttt ctaatgaaga tacatgatcg actattgaaa
    47281 gatagtcgag tatgatcact tagttaagta atcgaactct ctacttgctg aaatatc
//
LOCUS       DASHWW010000015        44952 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.015, whole genome shotgun sequence.
ACCESSION   DASHWW010000015 DASHWW010000000
VERSION     DASHWW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.015"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            212..604
                     /locus_tag="U2R64_000984"
     CDS             212..604
                     /locus_tag="U2R64_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8917819.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="U2R64_000985"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="U2R64_000985"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEM8917820.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="U2R64_000986"
     CDS             3165..4775
                     /locus_tag="U2R64_000986"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEM8917821.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="U2R64_000987"
     CDS             5067..5936
                     /locus_tag="U2R64_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEM8917822.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="U2R64_000988"
     CDS             6101..7372
                     /locus_tag="U2R64_000988"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEM8917823.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="U2R64_000989"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="U2R64_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HEM8917824.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="U2R64_000990"
     CDS             8763..9026
                     /locus_tag="U2R64_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEM8917825.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="U2R64_000991"
     CDS             9471..9920
                     /locus_tag="U2R64_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8917826.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="U2R64_000992"
                     /pseudo
     CDS             9977..11395
                     /locus_tag="U2R64_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
     gene            11395..12255
                     /locus_tag="U2R64_000993"
     CDS             11395..12255
                     /locus_tag="U2R64_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HEM8917827.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="U2R64_000994"
     CDS             12429..13202
                     /locus_tag="U2R64_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8917828.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="U2R64_000995"
     CDS             13349..13714
                     /locus_tag="U2R64_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HEM8917829.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="U2R64_000996"
     CDS             complement(13862..15070)
                     /locus_tag="U2R64_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8917830.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="U2R64_000997"
     CDS             complement(15089..15367)
                     /locus_tag="U2R64_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917831.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="U2R64_000998"
     CDS             15521..16216
                     /locus_tag="U2R64_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8917832.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="U2R64_000999"
     CDS             complement(16658..17455)
                     /locus_tag="U2R64_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HEM8917833.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="U2R64_001000"
     CDS             complement(17452..18636)
                     /locus_tag="U2R64_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEM8917834.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="U2R64_001001"
     CDS             complement(18661..19908)
                     /locus_tag="U2R64_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEM8917835.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="U2R64_001002"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="U2R64_001002"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEM8917836.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="U2R64_001003"
     CDS             21888..22202
                     /locus_tag="U2R64_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEM8917837.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="U2R64_001004"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="U2R64_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEM8917838.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="U2R64_001005"
     CDS             22887..23531
                     /locus_tag="U2R64_001005"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEM8917839.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="U2R64_001006"
     CDS             23546..23875
                     /locus_tag="U2R64_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HEM8917840.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="U2R64_001007"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="U2R64_001007"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEM8917841.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="U2R64_001008"
     CDS             24863..25687
                     /locus_tag="U2R64_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HEM8917842.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="U2R64_001009"
     CDS             25680..26027
                     /locus_tag="U2R64_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEM8917843.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="U2R64_001010"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="U2R64_001010"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEM8917844.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="U2R64_001011"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="U2R64_001011"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEM8917845.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="U2R64_001012"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="U2R64_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEM8917846.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="U2R64_001013"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="U2R64_001013"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEM8917847.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="U2R64_001014"
     CDS             31657..32451
                     /locus_tag="U2R64_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8917848.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="U2R64_001015"
     CDS             32441..34483
                     /locus_tag="U2R64_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917849.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="U2R64_001016"
     CDS             34764..34913
                     /locus_tag="U2R64_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEM8917850.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="U2R64_001017"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="U2R64_001017"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEM8917851.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="U2R64_001018"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="U2R64_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEM8917852.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="U2R64_001019"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="U2R64_001019"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEM8917853.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="U2R64_001020"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="U2R64_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEM8917854.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="U2R64_001021"
     CDS             39330..40412
                     /locus_tag="U2R64_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEM8917855.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISRHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="U2R64_001022"
     CDS             40412..41215
                     /locus_tag="U2R64_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEM8917856.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="U2R64_001023"
     CDS             41285..42025
                     /locus_tag="U2R64_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8917857.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="U2R64_001024"
     CDS             42036..43040
                     /locus_tag="U2R64_001024"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEM8917858.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="U2R64_001025"
     CDS             complement(43085..44929)
                     /locus_tag="U2R64_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917859.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14458 a         7837 c         9349 g        13308 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcgcgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgaccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctag acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac tt
//
LOCUS       DASHWW010000016        42887 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.016, whole genome shotgun sequence.
ACCESSION   DASHWW010000016 DASHWW010000000
VERSION     DASHWW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.016"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..305
                     /locus_tag="U2R64_001026"
     CDS             6..305
                     /locus_tag="U2R64_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8917860.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="U2R64_001027"
     CDS             378..1739
                     /locus_tag="U2R64_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEM8917861.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="U2R64_001028"
     CDS             1761..2021
                     /locus_tag="U2R64_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917862.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="U2R64_001029"
     CDS             2035..2787
                     /locus_tag="U2R64_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEM8917863.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="U2R64_001030"
     CDS             complement(2881..3486)
                     /locus_tag="U2R64_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8917864.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="U2R64_001031"
     CDS             complement(3539..4513)
                     /locus_tag="U2R64_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HEM8917865.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="U2R64_001032"
     CDS             complement(4891..5610)
                     /locus_tag="U2R64_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8917866.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="U2R64_001033"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="U2R64_001033"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEM8917867.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="U2R64_001034"
     CDS             7161..8558
                     /locus_tag="U2R64_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8917868.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="U2R64_001035"
     CDS             8639..9079
                     /locus_tag="U2R64_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8917869.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="U2R64_001036"
     CDS             9227..9553
                     /locus_tag="U2R64_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8917870.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="U2R64_001037"
     CDS             9554..10303
                     /locus_tag="U2R64_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917871.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="U2R64_001038"
     CDS             complement(10383..10838)
                     /locus_tag="U2R64_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEM8917872.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="U2R64_001039"
     CDS             complement(11265..11540)
                     /locus_tag="U2R64_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917873.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="U2R64_001040"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="U2R64_001040"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEM8917874.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="U2R64_001041"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="U2R64_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEM8917875.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENAFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="U2R64_001042"
     CDS             14770..17436
                     /locus_tag="U2R64_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8917876.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="U2R64_001043"
     CDS             17800..18552
                     /locus_tag="U2R64_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8917877.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="U2R64_001044"
     CDS             complement(18574..19728)
                     /locus_tag="U2R64_001044"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEM8917878.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="U2R64_001045"
     CDS             19913..22354
                     /locus_tag="U2R64_001045"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEM8917879.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="U2R64_001046"
     CDS             complement(22684..23388)
                     /locus_tag="U2R64_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917880.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="U2R64_001047"
     CDS             complement(23575..23820)
                     /locus_tag="U2R64_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917881.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="U2R64_001048"
     CDS             complement(23837..24688)
                     /locus_tag="U2R64_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8917882.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="U2R64_001049"
     CDS             24854..25858
                     /locus_tag="U2R64_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEM8917883.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="U2R64_001050"
     CDS             complement(26099..26455)
                     /locus_tag="U2R64_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8917884.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="U2R64_001051"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="U2R64_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEM8917885.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="U2R64_001052"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="U2R64_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEM8917886.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="U2R64_001053"
     CDS             complement(30815..31576)
                     /locus_tag="U2R64_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8917887.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="U2R64_001054"
     CDS             31854..32375
                     /locus_tag="U2R64_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEM8917888.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="U2R64_001055"
     CDS             32434..33294
                     /locus_tag="U2R64_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEM8917889.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="U2R64_001056"
     CDS             33479..35794
                     /locus_tag="U2R64_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8917890.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFAFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="U2R64_001057"
     CDS             35976..37817
                     /locus_tag="U2R64_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEM8917891.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="U2R64_001058"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="U2R64_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEM8917892.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39170..41269
                     /locus_tag="U2R64_001059"
     CDS             39170..41269
                     /locus_tag="U2R64_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEM8917893.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41465..42328
                     /locus_tag="U2R64_001060"
     CDS             41465..42328
                     /locus_tag="U2R64_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEM8917894.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42433..>42887
                     /locus_tag="U2R64_001061"
     CDS             42433..>42887
                     /locus_tag="U2R64_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEM8917895.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKE"
BASE COUNT        14097 a         7510 c         8869 g        12411 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttt taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaaggcgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgca ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    39121 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    39181 tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    39241 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    39301 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    39361 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    39421 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    39481 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    39541 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    39601 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    39661 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    39721 agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag gtaaagaaac
    39781 agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat ttactgaaaa
    39841 acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag aaatactcga
    39901 aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg atgctgaaaa
    39961 tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag aagagaacca
    40021 gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata ctgaaaaaac
    40081 acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga aaaaatcaaa
    40141 aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa gctgggctta
    40201 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    40261 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    40321 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    40381 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    40441 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    40501 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    40561 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    40621 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    40681 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    40741 tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata aagagaaaaa
    40801 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag aacaagcaaa
    40861 acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg tcgcacaagc
    40921 agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga atcagccaat
    40981 caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga cgtgggcacc
    41041 aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg ttgaaggagg
    41101 ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc tatatgccac
    41161 ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat tttacatcgt
    41221 aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat tttaggcaaa
    41281 tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg agtatgacac
    41341 aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat tcaagtagat
    41401 aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat agagggagaa
    41461 aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg aaaatgaaaa
    41521 aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag aaggtgaaca
    41581 caaaatcggt gaagcagttg aaggattcgg ttaccaaaat caaaaacatg aaaatcggat
    41641 cactacacaa attcctaaaa gccgtatcgg tcattacgct tttggaatcg ttactgctac
    41701 acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact ttgtcgtatc
    41761 tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc gcttgatgat
    41821 ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg aaaaaatatt
    41881 caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga taggaacagc
    41941 ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc ttgggtttat
    42001 ccatccttct gaacgatata atgaacctcg tctaggcgag cagataaaag gtcgagtgat
    42061 tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat atgaagctat
    42121 atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc agcaaatcaa
    42181 ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca gcaaaggagc
    42241 atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag aaaacggtgt
    42301 gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt aactagctta
    42361 taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt ataaattgtt
    42421 ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa acagcagcta
    42481 catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt gcttttggaa
    42541 aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa aaagagtccg
    42601 gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt gaaaattgtc
    42661 gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga aggcgccaaa
    42721 catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt agaagaggat
    42781 cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt aaaagatcat
    42841 cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaaa
//
LOCUS       DASHWW010000017        40141 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.017, whole genome shotgun sequence.
ACCESSION   DASHWW010000017 DASHWW010000000
VERSION     DASHWW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.017"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="U2R64_001062"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="U2R64_001062"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEM8917896.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="U2R64_001063"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="U2R64_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEM8917897.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="U2R64_001064"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="U2R64_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEM8917898.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="U2R64_001065"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="U2R64_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEM8917899.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="U2R64_001066"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="U2R64_001066"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEM8917900.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="U2R64_001067"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="U2R64_001067"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEM8917901.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="U2R64_001068"
     CDS             complement(8053..8523)
                     /locus_tag="U2R64_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HEM8917902.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="U2R64_001069"
     CDS             complement(8569..8994)
                     /locus_tag="U2R64_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEM8917903.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="U2R64_001070"
     CDS             complement(9061..9330)
                     /locus_tag="U2R64_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEM8917904.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="U2R64_001071"
     CDS             complement(9341..10936)
                     /locus_tag="U2R64_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8917905.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="U2R64_001072"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="U2R64_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEM8917906.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="U2R64_001073"
     CDS             complement(14489..15049)
                     /locus_tag="U2R64_001073"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEM8917907.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="U2R64_001074"
     CDS             15402..16376
                     /locus_tag="U2R64_001074"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEM8917908.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="U2R64_001075"
     CDS             16546..17946
                     /locus_tag="U2R64_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HEM8917909.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="U2R64_001076"
     CDS             complement(18024..18746)
                     /locus_tag="U2R64_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8917910.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="U2R64_001077"
     CDS             complement(18825..19331)
                     /locus_tag="U2R64_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEM8917911.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="U2R64_001078"
     CDS             19454..21253
                     /locus_tag="U2R64_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HEM8917912.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="U2R64_001079"
     CDS             complement(21321..22895)
                     /locus_tag="U2R64_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEM8917913.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="U2R64_001080"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="U2R64_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEM8917914.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="U2R64_001081"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="U2R64_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEM8917915.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="U2R64_001082"
     CDS             complement(24672..25310)
                     /locus_tag="U2R64_001082"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEM8917916.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="U2R64_001083"
     CDS             complement(25311..25961)
                     /locus_tag="U2R64_001083"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEM8917917.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="U2R64_001084"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="U2R64_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEM8917918.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="U2R64_001085"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="U2R64_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEM8917919.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="U2R64_001086"
     CDS             complement(29104..29844)
                     /locus_tag="U2R64_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEM8917920.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="U2R64_001087"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="U2R64_001087"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEM8917921.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="U2R64_001088"
     CDS             complement(31215..32153)
                     /locus_tag="U2R64_001088"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEM8917922.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="U2R64_001089"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="U2R64_001089"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEM8917923.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="U2R64_001090"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="U2R64_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEM8917924.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="U2R64_001091"
     CDS             complement(35313..35618)
                     /locus_tag="U2R64_001091"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEM8917925.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="U2R64_001092"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="U2R64_001092"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEM8917926.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36724..37008)
                     /locus_tag="U2R64_001093"
     CDS             complement(36724..37008)
                     /locus_tag="U2R64_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917927.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37026..37916)
                     /locus_tag="U2R64_001094"
     CDS             complement(37026..37916)
                     /locus_tag="U2R64_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HEM8917928.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37936..38154)
                     /locus_tag="U2R64_001095"
     CDS             complement(37936..38154)
                     /locus_tag="U2R64_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEM8917929.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38124..39824)
                     /locus_tag="U2R64_001096"
     CDS             complement(38124..39824)
                     /locus_tag="U2R64_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HEM8917930.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
BASE COUNT        10888 a         8719 c         7292 g        13242 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatca cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gtaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ctagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttagtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc caattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gacatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatacc gagaaaatgg tttttgaaca tcacttattc
    36601 aaaataaaaa aagattgtga cacgaatttt gtcacaacct ttaaatgtat tcctagagca
    36661 aagaagctaa gcgaagaaat ccaattctga ttatttattg tatttctttg ttcagcatcc
    36721 ttgctaaaag cccatattgg acaaagtatt cactacaccc atgatctcat cttttcgaga
    36781 acgtgctttt tctgtcggat cttctacctc ttctgtgtca attcgaacaa taaatttccg
    36841 attcatcgtc acgtaagcac cgtcgttgat caaaataaac agttcgttct cattatagtc
    36901 tgcacaggca tctttccata cgtcaaagcc gtttttttca gaagggatat cccgtttaac
    36961 cacagttttt ccacttaatt cgtggaacgt tacgtcataa tatttcatta tctctacctc
    37021 tttcgtcatt caatattttg tacttgttct ctgatttttt ctaagatcgt cttagactgg
    37081 acgacttgat ttttaatttc gattgcattt gatttggaac cgatcgtgtt gatttcccga
    37141 ttcatttctt ggatcaggaa atctaattcc cgacctacag gacattgtgc ttcgataagt
    37201 tcatctagtt tttgtacatg gatcgccaga cgatccagtt cctcgtgaat atctccgcgt
    37261 tccaacaaga tggctagctc cgtcaacaac cgttgctcat cgactttcgc tccaagaaat
    37321 tcctccagct ttttttgata ccttatttga aattcctttt catagatttc tacaaaacta
    37381 tcgagttttt ttagtacttc tttgaattct tcagtattct ttttcaacac taaagctaaa
    37441 gcttgacctt ctttttctcg actcgcctca atagaatcaa gtgcgctttt caatgtatct
    37501 agagctaact gtgccaattc ttccatgctc tcttccggtt tttcttctac cgttacgaag
    37561 ttttcgtcca gcgcgaagcg ttccgccatc cgactaattg acacttgatt ttgactaccg
    37621 tatcgttgtt gaattccgtc tgtcaattga gtgataagtg aatcaatcaa ttcccagttg
    37681 atgacgatct gtttttcgtt tttgccaata taagctagat tcacaaatac ttcgattcga
    37741 ccgcggctta actgctgttt aataagctga cgaaaatcgt tttcaacaaa gttcaggatt
    37801 ttaggacttc gtatttgaac atctagaaaa cgctggttga cactttttat ttcaatatct
    37861 aactgatacg cttttgtttc gcggatggct ttgccaaaac cagtcatact tttcattcga
    37921 cagggtcctt cctcattaca tattttctat tgctttttgc agttgttcaa actcttcgtt
    37981 cgtcaatgtc aggcctttcc ccattttttc atggtctggc gcccaatctc gaagatcgaa
    38041 ttttggcggg cgaccattcc agctgactag gttcagttct ttacgccacc ccttgttgtt
    38101 ttctgacaat atagcgattt cttctacgat ttcatatgaa aattcttgtg ccatggttgt
    38161 tcctccttga gataatataa atataggatc agtaatgtgt caactggttg cttaagcaat
    38221 tcatgctgca aacgatcctt gcgttttcct tgtagcagat aatcaaaata aacagttttc
    38281 gtgcgctcat tttgtatttt ttgctggtat tttcgatacc ttcgccattc ttcagtactt
    38341 aattgaccaa tttgtgccaa taaatcatcc ggcatacttt ttatatcttg ttggcagatc
    38401 atttgaatca tcatgtctac ttgatagatt tcattgggca gtaaaaaatg tttttttgct
    38461 aaaagttcta gcatcgccaa tccgcatgtc tctggtacga ccctgttctt atataaatta
    38521 cgcagttttt gccaaaattt tatgcttttg aaaaaagata attctaactg aatttctttt
    38581 gttaagtaag acaaaaatcc tcgccagtat gttcttgcag gtttaacaga atgaaatgta
    38641 taccagttcc catagtaata gcctaatcgt tttttcattt ccagatagcc taattgtaaa
    38701 tttaattggt tcctttggct atcaaaaagc agaaagctgc ctagtgtcca caatgtttga
    38761 catttccaat ggataaaaat gtctggcata cgaatttttt tcgctgggcc tggcccttgc
    38821 acatctacga caaatgcctc tgttgctcct ttgttaatcg caatatcaat aggtattttg
    38881 ttgcgatacc caccgtctgc atatttattt tttccgatct ttcgataagc catagcggga
    38941 taaaatgaag cagaggcgag tatccaatct ggtatttctt ctgtttttgt ctgttggata
    39001 tcagtcacta cttccgctag ttctggcagt ttagtagaca ccgtatataa acgtattttg
    39061 ggattatgtt tgagtaagga caaatccaaa ttgtctttga ccatcttttc caatggagca
    39121 gaagaaaccc cgccttcaat tagtgctgtt ttcgtcattt ggcgtctttc tcgatagaag
    39181 cgttcacgaa ggtcttcaac tgcagccatt tctggtaacg caagcacttg tcttgtcgac
    39241 agctttttcc ataaattcac agcttttttc atatctcctt gtaaaatcaa tgcgccgttc
    39301 aacgcaccta ccgaggtacc tgtgataatc tcaaagttga tatcatgttc cttcagcgcc
    39361 tgccacacac caatctgata agcaccgtgt gctcctcctc cacctaaaac aagtgctgta
    39421 tgatagacca gctttttatt taattgtgtg gttccttgat agccgttttt atgaaaaata
    39481 cgcaaccatt cttctgatag aggagattga aataaaaaac aacagttttc tttaataaaa
    39541 aaacgagcgc aagcttccat ataccgaaaa aattttttcc attcaaaagt ttcaccttca
    39601 atcaacagat tattaaaaat aacatctcct ctacttttag caatagtaaa atagacggta
    39661 tattttttcg atactgcttt aaaagcacat tgcttttttg cagaacgcca aaaagcgtct
    39721 ctactttctt gatgactttg aaaaaatgga aggggttgtt ttgcttgctg gataggcgaa
    39781 tacagcgaca ttttctgtga aaagtaaact ttttttatct ccatcgcgct ctcctttttc
    39841 ttcaagtata ccagtacgtc ataaaaaggt catgagtctc gtattcgact ttgtagattc
    39901 cataagaaaa caattcataa aacatccttt aaataaaaaa tacaaaaatc acaaaaatta
    39961 attgaaaatg agagtgtttt caatgaaaac gtgattttgt aatggaattt taaaataaaa
    40021 gaaacaagct tttttaatgc aaatgttgta aaataaaaga gattaagagg aaataagagg
    40081 aggaacatga tgactgagtc agtttatgta catattgata ccacaagtaa tgctgtttta
    40141 a
//
LOCUS       DASHWW010000018        38914 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.018, whole genome shotgun sequence.
ACCESSION   DASHWW010000018 DASHWW010000000
VERSION     DASHWW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.018"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            309..1448
                     /locus_tag="U2R64_001097"
     CDS             309..1448
                     /locus_tag="U2R64_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HEM8917931.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEELTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1515..2090)
                     /locus_tag="U2R64_001098"
     CDS             complement(1515..2090)
                     /locus_tag="U2R64_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8917932.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2095..3069)
                     /locus_tag="U2R64_001099"
     CDS             complement(2095..3069)
                     /locus_tag="U2R64_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HEM8917933.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3093..3137)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3352..4320
                     /locus_tag="U2R64_001100"
     CDS             3352..4320
                     /locus_tag="U2R64_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8917934.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            4433..4711
                     /locus_tag="U2R64_001101"
     CDS             4433..4711
                     /locus_tag="U2R64_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEM8917935.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCTYAKKEFEKKPEYQDVLRQS"
     gene            4829..5065
                     /gene="secG"
                     /locus_tag="U2R64_001102"
     CDS             4829..5065
                     /gene="secG"
                     /locus_tag="U2R64_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEM8917936.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            5168..5923
                     /locus_tag="U2R64_001103"
     CDS             5168..5923
                     /locus_tag="U2R64_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8917937.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5926..8283
                     /gene="rnr"
                     /locus_tag="U2R64_001104"
     CDS             5926..8283
                     /gene="rnr"
                     /locus_tag="U2R64_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEM8917938.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWATELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8305..8769
                     /gene="smpB"
                     /locus_tag="U2R64_001105"
     CDS             8305..8769
                     /gene="smpB"
                     /locus_tag="U2R64_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEM8917939.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9071..9790
                     /gene="atpB"
                     /locus_tag="U2R64_001106"
     CDS             9071..9790
                     /gene="atpB"
                     /locus_tag="U2R64_001106"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEM8917940.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9843..10058
                     /gene="atpE"
                     /locus_tag="U2R64_001107"
     CDS             9843..10058
                     /gene="atpE"
                     /locus_tag="U2R64_001107"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HEM8917941.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            10149..10673
                     /gene="atpF"
                     /locus_tag="U2R64_001108"
     CDS             10149..10673
                     /gene="atpF"
                     /locus_tag="U2R64_001108"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEM8917942.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10660..11202
                     /locus_tag="U2R64_001109"
     CDS             10660..11202
                     /locus_tag="U2R64_001109"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEM8917943.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            11225..12781
                     /locus_tag="U2R64_001110"
     CDS             11225..12781
                     /locus_tag="U2R64_001110"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEM8917944.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12795..13697
                     /locus_tag="U2R64_001111"
     CDS             12795..13697
                     /locus_tag="U2R64_001111"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEM8917945.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13720..15126
                     /gene="atpD"
                     /locus_tag="U2R64_001112"
     CDS             13720..15126
                     /gene="atpD"
                     /locus_tag="U2R64_001112"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEM8917946.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15140..15562
                     /locus_tag="U2R64_001113"
     CDS             15140..15562
                     /locus_tag="U2R64_001113"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEM8917947.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16031..16261
                     /locus_tag="U2R64_001114"
     CDS             16031..16261
                     /locus_tag="U2R64_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEM8917948.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16358..17659
                     /gene="murA"
                     /locus_tag="U2R64_001115"
     CDS             16358..17659
                     /gene="murA"
                     /locus_tag="U2R64_001115"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEM8917949.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTEIMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17672..17848
                     /locus_tag="U2R64_001116"
     CDS             17672..17848
                     /locus_tag="U2R64_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEM8917950.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17983..18279
                     /gene="yidD"
                     /locus_tag="U2R64_001117"
     CDS             17983..18279
                     /gene="yidD"
                     /locus_tag="U2R64_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEM8917951.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            18463..18930
                     /locus_tag="U2R64_001118"
     CDS             18463..18930
                     /locus_tag="U2R64_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8917952.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            19015..19899
                     /locus_tag="U2R64_001119"
     CDS             19015..19899
                     /locus_tag="U2R64_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8917953.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            20044..20250
                     /locus_tag="U2R64_001120"
     CDS             20044..20250
                     /locus_tag="U2R64_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEM8917954.1"
                     /translation="MRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGPKEYEIFFGE
                     EDFGKEKSLENAIETVIRHWNLHE"
     gene            20338..20418
                     /locus_tag="U2R64_001121"
     tRNA            20338..20418
                     /locus_tag="U2R64_001121"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20372..20374,aa:Tyr,seq:gta)
     gene            20425..20496
                     /locus_tag="U2R64_001122"
     tRNA            20425..20496
                     /locus_tag="U2R64_001122"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20457..20459,aa:Gln,seq:ttg)
     gene            20621..20791
                     /locus_tag="U2R64_001123"
     CDS             20621..20791
                     /locus_tag="U2R64_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917955.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            21011..21718
                     /locus_tag="U2R64_001124"
     CDS             21011..21718
                     /locus_tag="U2R64_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8917956.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(21778..22422)
                     /locus_tag="U2R64_001125"
     CDS             complement(21778..22422)
                     /locus_tag="U2R64_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEM8917957.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            22549..22836
                     /locus_tag="U2R64_001126"
     CDS             22549..22836
                     /locus_tag="U2R64_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8917958.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            22944..23264
                     /locus_tag="U2R64_001127"
     CDS             22944..23264
                     /locus_tag="U2R64_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8917959.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            23345..24658
                     /locus_tag="U2R64_001128"
     CDS             23345..24658
                     /locus_tag="U2R64_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEM8917960.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            24655..25374
                     /locus_tag="U2R64_001129"
     CDS             24655..25374
                     /locus_tag="U2R64_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEM8917961.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            25502..26053
                     /gene="raiA"
                     /locus_tag="U2R64_001130"
     CDS             25502..26053
                     /gene="raiA"
                     /locus_tag="U2R64_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEM8917962.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            26275..28809
                     /gene="secA"
                     /locus_tag="U2R64_001131"
     CDS             26275..28809
                     /gene="secA"
                     /locus_tag="U2R64_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEM8917963.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            28935..30036
                     /gene="prfB"
                     /locus_tag="U2R64_001132"
     CDS             join(28935..29006,29008..30036)
                     /gene="prfB"
                     /locus_tag="U2R64_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEM8917964.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            30141..30827
                     /gene="ftsE"
                     /locus_tag="U2R64_001133"
     CDS             30141..30827
                     /gene="ftsE"
                     /locus_tag="U2R64_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEM8917965.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            30811..31704
                     /locus_tag="U2R64_001134"
     CDS             30811..31704
                     /locus_tag="U2R64_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8917966.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            31856..33304
                     /gene="cls"
                     /locus_tag="U2R64_001135"
     CDS             31856..33304
                     /gene="cls"
                     /locus_tag="U2R64_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEM8917967.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            33641..34498
                     /locus_tag="U2R64_001136"
     CDS             33641..34498
                     /locus_tag="U2R64_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEM8917968.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            34613..35533
                     /gene="pstC"
                     /locus_tag="U2R64_001137"
     CDS             34613..35533
                     /gene="pstC"
                     /locus_tag="U2R64_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEM8917969.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            35533..36417
                     /gene="pstA"
                     /locus_tag="U2R64_001138"
     CDS             35533..36417
                     /gene="pstA"
                     /locus_tag="U2R64_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEM8917970.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            36432..37238
                     /gene="pstB"
                     /locus_tag="U2R64_001139"
     CDS             36432..37238
                     /gene="pstB"
                     /locus_tag="U2R64_001139"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEM8917971.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            37254..38012
                     /locus_tag="U2R64_001140"
     CDS             37254..38012
                     /locus_tag="U2R64_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEM8917972.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            38025..38702
                     /gene="phoU"
                     /locus_tag="U2R64_001141"
     CDS             38025..38702
                     /gene="phoU"
                     /locus_tag="U2R64_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEM8917973.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
BASE COUNT        12866 a         6768 c         8459 g        10821 t
ORIGIN      
        1 atcagcaggt agagagtttt ttttgcaact agcttctgta tatgatgttt acaaagaatg
       61 gtacaagaaa agatcatcct tgaaaaagga aagctaacaa taactagcat catataagag
      121 cttttaagga tagaacagta gaataggaat ctatgagcaa gtcctctcgt ataaataaaa
      181 taggagggaa gtagcagcat atttttcata aagtggctct ctttcttcat ttttactttg
      241 gttgctccta tttgaaaatt cgagcacact caaatacaat aaaaagaaat ggcaagggag
      301 aggattagat gaaaaaagaa gaaaaaatcg cgattttaca agagatcatc cgaattaaat
      361 cagtgaatgg aaacgaaggt gaagtagcag cctatttgaa taagcttttg gcaaagcatg
      421 acataacagg agagattgtt tcttacagag atggtagaga taatttgatt gctcgttacc
      481 aaaagggcca atcaggaaaa gtgttaggcc tatctgggca tatggatgtc gtggcggctg
      541 gtgatgaatc gtcttggacc tatgcaccct ttgcagcaga aatccatggg aaccgtttgt
      601 acggacgtgg tgctacagat atgaagagtg gcttggcagc aatggtgatt gccatgatcg
      661 aactgaaaga gtcaggaaaa ccatttaacg gaacagtcaa attattagcc actgtcggag
      721 aagaagtggg tgaactaggt ggggaagagc tcacgaaagc aggctatgta gatgacttag
      781 atgccttgat catcggagag ccaactaatt acagtttgat gtatacgcac atgggatcaa
      841 tcaactatac agtcacctcg cacggaaaag aagcgcatag ctctatgcca gaccaaggtt
      901 ataatgcaat caatcaccta aatgaattca ttacgaaagc aaatgctgaa atgaatcacc
      961 tcgctgaaac aatcgagaat cctgtcctag gaaaaacaat ccataatgtt acattgatca
     1021 gtggcgggaa tcaagtcaac agcatcccaa gccatgcgca gctccaaggg aacattcgat
     1081 cgattccaga atacccaaat gataaaatca ttgcattgct gcaatcaatc gtcaatgaat
     1141 tgaatcaaga gacagactat catttggaat tgatgatcga ttacaacaaa atacctgtca
     1201 aagctgatcc agattctcct ttgattcatt gcattcagca acaattcagc cagccattac
     1261 ctttagttgg agcggcagca acaacggatg cagccgaatt tacgaaagct aaccattcct
     1321 tcgactttgt cgtctttggg cctggtgtcg ttactttgcc tcatcaagta gatgagtatg
     1381 ttgaaatcga taattatttg gatatgattg aaaaatatca aggaattatt ttatcctact
     1441 tagcgtaaga tttttttaat aaatgaaaaa acagagccag attagcatta ttttgctaat
     1501 ccagctctgt ttattcagcc tatttttctt tttgaatata tcaagcgttg tggcaacata
     1561 gtgatgacta atgaaacaac gacgatagac aacaaacgat caaggtagtc tgtacctgcc
     1621 tgtaccaaga tcacacttgt tgtctgactt aaacctaacc catgtaatag ctgaacgatc
     1681 atactggatc ctgaggaggt gatcccgcca aataactgaa cggtaatgat cgaagaaacg
     1741 atcgttccag gtaccgacaa aatcaaagcg agtaataaca gtttcaagct gtttttatct
     1801 ttgccgagat atcttggcaa aatcaatcca gcaagcaagc ctgtgagaat ttggattggc
     1861 gaataataca gagaaaaaat atctgtagtc actccactta aaataccgct ggacaatcct
     1921 gtcagcattc caggtacagg cccaagcaat gcaccagcaa aaatcgttcc gatagaatcg
     1981 agatagattg gcaaacgaag ccataaagca atcgttcctc caatataatt gatcccaata
     2041 cacaaagcca tcactgtaag tacgcgagtt gccattttgt ttttattcat tttgttagcc
     2101 catctttaac ctttccaaat ctttcataat cgtttcttct tgtgcattta aaagaacggt
     2161 taaaaacttt cggaaaaaaa gacgagtatc tacttttgtc ataattttac tgttagcagg
     2221 tttctgccaa aattcataac gatcaaccaa tgtttgtcca cgacttattc cttgagtttc
     2281 cacagcagtg aagcttttga aaccttcaca gatggccccc tcgataaaat aagcaacagc
     2341 taacggatca ttgatgacac atcctaaaat tctttcttgt ttccagtgga agtcaaaata
     2401 aaaacgagtg atcgctttta gatactctcc ctcttcagga ttcatttgac agcagtattc
     2461 gaggatagtc ggtgtcaaga cgatttctct tgtcacatct aacccaacca tttctatcgt
     2521 ttgtttgaga ttctcgaata cataagaagc tgcttcagga tcacaccagt aattgtattc
     2581 agcaactggc gaacagttac catggctttt gtaagttcca cccatcgaga caaaacgatc
     2641 catatgtttc ccaatatttg ggttgacttt caaagcaaaa gcgatattgg tcaaaggacc
     2701 caaagcaatg actgatgtat ttgtcttttc tttgaaataa tcagccaaaa aatcaacggc
     2761 atggagaggt tctgcctgtt ttctcaagat catcgggaaa tttgtttccc ctaaaccatc
     2821 cataccatga gtgtcttgtg cactgatgaa aggttgcttc aaaggttttt ccattccttg
     2881 ataaacagga atgtctaaac gatcacagcg ttccaggcat ttcagcacat tctgcgtacc
     2941 tatatctgca gggacattcc cacaaactac ggtaatagca actacttcga tatcagggga
     3001 tttgacagct aatgataaag ctaaagtgtc gtcgatccct ggatcgcaat caataattac
     3061 ttttcgcatt atttccaatc tcctttcttt agagatactt agttttttat tctgggaagt
     3121 ttccgaacca gtccaagacg agcgtcttga ttataatgca cgaaattagt atactggctt
     3181 ttattgcgaa tgtaaatgct ctcttacaag taaatctatt gaggagaact ttaagtaaat
     3241 gatacaatga aaaagaaatg gaatttacgt gtgccgaaaa taaagaatcc tatggatcgg
     3301 tacattggat aatagttaga ttatagtttg gcagaaagcg gcgggtgtac aatggttatt
     3361 ttttatttca ttcttattct gataattata gggatcagtt accattttct ttcttatttt
     3421 tatgcaaaga aattagtaag agcgggagta cagagaggat atgactggta tgaagacact
     3481 ggtcatcgtt tgatggaccc tgctgcagtc acgtcagtag aaaaaaaacg acaaaaatta
     3541 gaagaagagt gtgaaagctt ttgggagcag ggaacaccca aaacaatcaa aagttatgac
     3601 gggttgaaac tagctggtca gatgttcatc catccaaata agcagaataa atgggtcatt
     3661 tgcgtacatg attaccgaag cacagggaaa agagacatgt ctcatatagg taaaagatat
     3721 gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga aagtgaagga
     3781 gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat ccaactcatc
     3841 ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg agcttctacg
     3901 atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat tttagacagc
     3961 ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac tgtctttcct
     4021 aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg ttactcctta
     4081 aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt ggtcattcat
     4141 ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa tgctacggca
     4201 ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc gatgaaagat
     4261 ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac gatgaattaa
     4321 ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga tcaggagact
     4381 gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc atatggaaat
     4441 caaagaagaa aaaaatcgtc ttgctttatt caatgatgaa caacaagaga tcggagaaat
     4501 gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg tagatccagc
     4561 atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat tagcaagacg
     4621 agacgggaaa aagatcattc ctttatgcac ttatgcaaaa aaagagtttg aaaagaaacc
     4681 agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt tgaactttca
     4741 gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa gttaaagaga
     4801 cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa tcgtgatcgt
     4861 tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa atagtgcagc
     4921 gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc gcggctttga
     4981 agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct tattatttgt
     5041 cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc gggcggcttt
     5101 ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt aaaatgaggc
     5161 gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac atggaaagcg
     5221 agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa tgctcgcacg
     5281 atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac acggaacaat
     5341 ggagccatat gatattttgc aagaaaaagc agaaagctgg tgggcagaca ctaaaaaagc
     5401 catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat tatcaatggg
     5461 cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg gttttttctg
     5521 ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat acgtacgtca
     5581 agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag ttgcttaccg
     5641 ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg tagaaagtag
     5701 gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg aaatgatcga
     5761 ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga cacttcgatg
     5821 gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat tagaaaaaga
     5881 cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac aaaagaaacg
     5941 ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt ttctatggaa
     6001 gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact agtacaaacg
     6061 attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa agtgaaactt
     6121 cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg atttggattt
     6181 gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac tggttttgca
     6241 atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga tatggatcgc
     6301 ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt agcaggggaa
     6361 ttcgttgctt attcagaaga agaaatacaa gaaacggatc tttacggcgt tgttatcccg
     6421 aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt tcgtccagtt
     6481 gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta tgcgactagt
     6541 ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat ggatatcctc
     6601 tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt gtctgaagca
     6661 gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga tttaagaaat
     6721 cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc agttacggtt
     6781 aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt ttcttactat
     6841 gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag tgtatatttg
     6901 actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg ttcactgaat
     6961 ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa tggacaagta
     7021 gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac ctacacagct
     7081 gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc tcagctcgta
     7141 cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg aatcaaacgt
     7201 ggcgcgattt cttttgagga tcgcgaagca aaaatccttg ttgatgctga aggacaccca
     7261 aatgatatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc tttcatgctt
     7321 gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt tatttaccga
     7381 atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc ttcagctttg
     7441 ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca gcatgtgatc
     7501 gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct aagaagcatg
     7561 caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc agattactac
     7621 acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg tctgatccgt
     7681 tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctacgga acttcctgaa
     7741 attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg tgaagtagat
     7801 tccatgaaga aagcagaatt catgatggac aaagtggggg aagaattcga tgggatcatc
     7861 agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga gggattgatc
     7921 catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt agctcttgta
     7981 ggtgaaagaa ctggtctgac ttttaaaatc ggacagaaag tgcgagtaaa agtagtcaaa
     8041 gctgatccag atgaacgagc agtagatttt gaacttgttt ccgcagaaga ggttacagcg
     8101 ttggaacggc caaaaacacg aaatggaaaa tcaggaaaac gcgaaggaaa acaagcagga
     8161 aaacgcccag aaagaaatgg caagaagaac aaacgatata gcgatagtaa gcaaacgttc
     8221 ggtaagaaaa aagggaagaa gccattttac aaaggtgtta aaaagaagaa aaagaaaaaa
     8281 taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaattaat tgcacaaaac
     8341 aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat ggtcttgcaa
     8401 ggaaccgaga tcaagtcgat acgaaacagc cggatcaatc taaaagatgg atttattcgc
     8461 gtccgcaacg gagaagcttt cttgcataat gttcatatca gtccttatga acaaggaaat
     8521 atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaaaaa acaaatcatc
     8581 cggcttgaaa atgaattgaa aaatactgga atcactgttg ttcctttaaa agtctatatt
     8641 cgtaacggct atgccaaggt attgattggt ctggcgaaag ggaaaaaatc ttatgataaa
     8701 cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt aaaaaatttc
     8761 tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta cttaatgata
     8821 aaatttgtta gcatttaatc tgataaaaca tgattatcat aggttttttc ttagatcagg
     8881 agcaccgtgt ataaagaaaa attcgcttcg tttttgactg aaataaaaaa gtgtctaatt
     8941 ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt ggttagaaac
     9001 cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg gggaaaagag
     9061 gtgaaatgga ttggatgaac gctcgctaac gttccacatt ggaccaattt ggtttgatgg
     9121 tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag cttacttttt
     9181 tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat gggtcattga
     9241 ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca atttccattt
     9301 gttggcattt acattgtttt tatttgtttt tgttgcaaac aacatcggtt tagtaacaaa
     9361 aatcgtttta cctaacgaaa caacactttg gaaaagcccg acagcagacc cgtttgttac
     9421 tttaactttg gcatttataa tgatcttact tactcactta tttggggtga aaaagttagg
     9481 cttcaaagga tatttcgtaa attcgttctt gaaaccatat agttttatgt ttccgatgaa
     9541 actgattgaa gaatttacaa acttattaac acttgcttta cgtctttatg ggaatattta
     9601 tgcgggggaa gttttgctaa ccttgattgc aaaaatggta ataagcttag gctggttctc
     9661 attgccgtta gcaattccat tagagatggt ctggatcgca ttctccttgt ttatcggaag
     9721 catccaagca tttgtcttcg ttactttatc tatggtttat atgagccata agattgaagt
     9781 ggaagaataa tattcgtttt aaaaacaaac tactatttat ctaatttagg aggaaaacaa
     9841 ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga gccggttatg
     9901 gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct gaaatgtctg
     9961 gtcaattccg tacaacaatg tttatcgggg tagctctagt cgaagctgtt cctatcttag
    10021 gggtagttgt cgccttgatt ctagtttttg gtgtttaatt gaatcagtat taaggcagaa
    10081 acaatttggt ttgttactgc ttttttacat gaaaactaga agtacttcaa agaaaggaag
    10141 gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg ttaggaaatg
    10201 tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcat tttgcttggg
    10261 gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat ttggattctg
    10321 cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa caattgttag
    10381 cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga gaattaagcc
    10441 gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagt aaagcccaag
    10501 ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgat gttgcagaac
    10561 tatctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa atgcacgaat
    10621 cattaatcaa tcaatatatc gaaggtctag gttcttcaaa tgaaactaga taaatataca
    10681 gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa taaagcagaa
    10741 gaaatttatc aagatctcgt aagcttacgt caaatctatg aacaagtacc tggattaggt
    10801 aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat ggacaagctt
    10861 gttagtggct atgatggaat cgttaaaaac tttttagaag ttgtttatgc gtataaccga
    10921 atggatgatc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga acatcaaggt
    10981 ttgctgttgg gaagtgtcac aacagcagtt ccactttcag acgaacaacg aatacaatta
    11041 gaaaagaatg ttgcaaaaac aatgaactat caatcagtcg aattaaaaca aatcgttgat
    11101 tcttctatta ttggtggcgc gattgttgaa gctaaccatc gagtaatcga cggaagcatt
    11161 cgcacgcaat tagaaaatat gcgtaatcaa ttaaatagat agtacaaaga ggtaggtgaa
    11221 tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa ttgaaaatta
    11281 tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg acgggatcgc
    11341 tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt caaatggctc
    11401 atacggaatg gcgcaaaact tagaatcaaa tgatgtaggt atcattatcc ttggcgattt
    11461 cgagtccatt cgtgaaggag ataaagtaaa acgaacagga aagatcatgg aagttccagt
    11521 tggagaggcc ttgattggac gggtagttaa tccgctaggt cagccaattg acggactagg
    11581 tgaaatcgtt actgacaaag ctcgtccagt agaagcaatg gcaccaggcg ttatgcaacg
    11641 taaatctgtt aacgaaccaa tgcaaacagg tctaaaagca atcgacgctc ttgtaccaat
    11701 cggacgcggc caacgtgaat tagttatcgg tgaccgtaaa acagggaaaa cttccattgc
    11761 gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg tagcaatcgg
    11821 acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg gcgcaatgga
    11881 ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagcg ccgttgcttt atatcgcacc
    11941 atatgctggt actgcaatgg gtgaagagtt catgtacaac gggaaacatg tcttgatcat
    12001 ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc tgcttcgccg
    12061 tccaccaggt cgtgaagctt atccagggga tgttttctac ttacactcac gcttattgga
    12121 acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct taccatttgt
    12181 tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt cgatcactga
    12241 tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag cggttgatgc
    12301 cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga aaaaagttgc
    12361 tgggacttta cgtctagact tagcaagtta ccgtgaatta gaagcattta cacaattcgg
    12421 ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta cagtagaaat
    12481 cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga ttttgtatgc
    12541 tttgacacat ggattcttag atagtatccc tgtagacagt attttagact tcgaacatga
    12601 attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc gtacaacaaa
    12661 agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag acatgttctt
    12721 agctacaaaa ggaaataatt cctctacaga agataaattg aaatccattc aaaatgcata
    12781 gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc gcttcaacga
    12841 aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag ttgacaaaat
    12901 ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa atcgttacgc
    12961 atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg gatatcaatt
    13021 acaacagcat gttgctcagc cgtcctgtta agaaaacggg ttatatcgtc atcactgcag
    13081 atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg tctattttag
    13141 aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga actggtgcag
    13201 acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta tctgatcagc
    13261 caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgtac caaaacgaag
    13321 tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact agtcagtttc
    13381 gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaact actttcgaac
    13441 aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg cctcagtatg
    13501 ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat gctgctggta
    13561 tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag ctgacggttt
    13621 cttacaaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt gttgccggag
    13681 cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg caagattgtt
    13741 caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt accagatatc
    13801 aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt tcttgaagca
    13861 gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac agatggttta
    13921 caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt aggtaaagaa
    13981 acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac acctttccca
    14041 gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga attaagtaca
    14101 agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc atatttaaaa
    14161 ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact gatccaagaa
    14221 ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg tgtaggtgaa
    14281 cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt tatcgaaaaa
    14341 acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg tgttgctttg
    14401 actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt actgttgttt
    14461 atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt gttaggacgg
    14521 atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca attgcaagaa
    14581 cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta tgtgccagcc
    14641 gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc gacaaccaac
    14701 ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt ggcttcttct
    14761 tcaagtgctt tagcacctga aatcgtggga gaagaacatt ataaagtagc aacagaagtc
    14821 caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt aggtatggat
    14881 gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca attcttcttg
    14941 tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata tgtccctgta
    15001 gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga tcttcctgaa
    15061 gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa aacactaggc
    15121 tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa ctcctgccgg
    15181 tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg gtgagcttgg
    15241 gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag ttcgtgtaaa
    15301 acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa tcatggaagt
    15361 tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg atatcgatgt
    15421 atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag caaaagcaaa
    15481 acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa tcaatcgtat
    15541 caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt aagaacagta
    15601 aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt acgaaaattg
    15661 cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc tggaacaccg
    15721 tatatcggag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aatggaaaat
    15781 agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat tgaacaccgt
    15841 ttatttggaa taagggactg cgacaagact tttgtctcag tccctttttt tgcatatttt
    15901 tagcatttat ttcctaaaaa atgtaagggg attcctatat ttttaagtat acttgttttt
    15961 ccttttatac attttatggt attatcattt tattagttat tataaaacaa tcgttagaaa
    16021 ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga gtcatttggc
    16081 gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt ttttcagacc
    16141 aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt tagggtacac
    16201 tgcaagtaat tttttcttag aagttatcgc tttatgccga aatcttttcg ttagcctgta
    16261 aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa gattttgagt
    16321 aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca tcgtaagagg
    16381 tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg ttttgcctat
    16441 tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg ttccgattct
    16501 ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg tagattttga
    16561 tgaacaaaag aatcaagtaa caatcgatgc ttcaagacaa ttagaaatcg aagcgcctta
    16621 tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac ttgccagaaa
    16681 tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac caatcgattt
    16741 gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg gctatatcga
    16801 agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta gtgtaggtgc
    16861 tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca ttgaaaacgt
    16921 agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg gcgctcaagt
    16981 ctatggagct ggtactgaaa taatgcgtat tgaaggcgtg gatcatttac atgcagtcaa
    17041 ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg ctgcaatgac
    17101 acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat tgatttctaa
    17161 attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg tcatcggacc
    17221 aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc ctacagatat
    17281 gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtag tgactgaaac
    17341 agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg ctcatgtcaa
    17401 aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg cagaagtata
    17461 tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag caaatggaat
    17521 cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc atatcaaact
    17581 acagcaatta ggtgcagacg ttgaacgtgt agacatggat caaacttctg ctgaaaaaac
    17641 agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata tcttattaac
    17701 tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg ccggaacgat
    17761 gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc caagtttgtg
    17821 gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc tagtcgatat
    17881 gaagtgagcc atgaagcaga acatgacaaa agaaaacaga agggaacgtt gacgttagtc
    17941 gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa gatattgatt
    18001 tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag ctgccgttat
    18061 tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc actaaaaggg
    18121 acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg cggtatcgat
    18181 tatgtaccat tgacattcca attaacgcga aataagaaag ataaaaaaga accagattat
    18241 aaaaaggttg tgaaaaatac gagtagcact gagcgataaa gaaacaattt ggaaaatagc
    18301 ttcttatatt ttgcaaaatt gtgagttatt gccgaagtgt tggattttga acaccgtcaa
    18361 aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg aaaattattg
    18421 tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga agaactaaac
    18481 aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga aaaagttcaa
    18541 gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac aataggtgta
    18601 ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt agccccaacg
    18661 tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa gctttcacaa
    18721 ctcgcttcca gtcaaactca gatcatcata cgaaccggca gtactagcag tgcggcgtta
    18781 catctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta ttttatccat
    18841 cattactctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt aattttagca
    18901 attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa atgctttcaa
    18961 atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat ttttatggga
    19021 atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga tggcaaagag
    19081 attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa agcgcaatta
    19141 tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg aatcagctct
    19201 cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat tccttatatt
    19261 catggattta atattttccg agatttggaa actctgtttc aactcccagt aacgattgaa
    19321 aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg tgattatcaa
    19381 gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac gaaaggacaa
    19441 atcaataaag gggcacatct ttatggtgga gaatttgggt tgatgttctt aaatggcgat
    19501 aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg tgaacgcaaa
    19561 ggtctcgata aaaattctta taccggaaaa gatgtctttg aattagcaga aactggagat
    19621 gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg attattcagt
    19681 attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggtgtttc tgcaaaagaa
    19741 gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt cgatctgcat
    19801 gatttcgaac cgcagatttt attatgtgaa tacagaaacg atgctaatct tgtaggtgca
    19861 gcagcaaact atctcgctgt acgtcaaggg gagaattaag agctttagag aaggtgcagc
    19921 ttgcataaaa gaagtgaatg aaatgaatag gagattttta cctaaggaat gttttatttg
    19981 ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaaa taaagatgtt
    20041 gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga agtcactcag
    20101 ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa agaatatgaa
    20161 attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc gatagaaaca
    20221 gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt caataaaggg
    20281 ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa acctttcgga
    20341 ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg ttcagtggtt
    20401 cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa gggactttga
    20461 ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt aagctctcgt
    20521 tagttcgaga gctctttttt ttgctttgct accttgttcc ttgaagattc tgctgattta
    20581 agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga aagaaaaagt
    20641 agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca atattgaagt
    20701 gaatattccg aaaaaaggcg gaaaagcggt ccaggtaaaa tcaaaacgcc caacgaatca
    20761 tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata agtcggcatt
    20821 ttcatcgatt ttagggtctt ttgttatttt ctaggttgaa catatctaaa aaattgtttc
    20881 tgacaatagg agtaggaaga acgatgtgtg tctaaatcct ctgttgatgg atagaaacct
    20941 ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa cgaaaggacg
    21001 ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc aattaaaaaa
    21061 tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa gagaattagc
    21121 agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact tggcagatga
    21181 aggaatctta gaaagaaaga tcggttcggg tacatatgtt gcgcgagaaa aagtacaaga
    21241 aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcgcaaaatc gagtaccgtc
    21301 tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg aaaaactaaa
    21361 cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag atgatgtccc
    21421 tatttgtttt gaagttgcca gtgtgccaca aaagctgatc gatggctaca gcaaagcaga
    21481 gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga tcggtccagc
    21541 gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt tagaggtaaa
    21601 acgaggagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg gtacgccgtt
    21661 tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg aaaaataaaa
    21721 aacaggtgat ccctgattcc ttacttagaa ataaaagaga atcagaatca cctgttttta
    21781 tatatgatca gttaccagtt gctcgtgata agaaacagga ccctcttcaa attggacttg
    21841 tccgttcagc agctcaatga tggattcttt aaagtggtca gcactttttt catctacagc
    21901 acagatgacg ctaacttgat cagtatattg gatttctttt ataaaaaaat gttggagttc
    21961 aagataattc tgtaattttc ctagttgcgg atacgtgatc atcacagaga tctcctgttg
    22021 caaggtacct tctacgattc caatgtcaga caatgcttga gagacagcat gagtgtatgc
    22081 tcgtattaat ccgcctgtgc cgagtttcgt tcctccaaaa tatcgagtga ctactgcagc
    22141 tacattgatc agttgatttt ttttgaggac ttccaacatc ggtacgccag ccgttccact
    22201 tggttctcca tcatcgctgc ttcgctggat ttcatttttt tctccaatga tgaaggcgct
    22261 gcagttatgg ttcgctttcc aatgttcttt ttttatttct tgaatgaaac tttttgcttg
    22321 gtcctctgat tctattcgtc taagagaaca gataaagcgt gattttttga tctcaatctc
    22381 actttgtcca ttttctttta ttgtacgata gcgctcgatc atcttgtcac ctcttttttt
    22441 cattttcttt attcagtata aataaagttc taggttgttt caacactgta acggttgcgc
    22501 aatcgctgta gtatgcgata ataaagacaa aggtaggtgg atctggggat gcaggaacga
    22561 atgaaaaagt acgatgcaat tacgcattat ttgaagaaca atggcggctc tcaagtaacg
    22621 ttgaccttta cccaatttga cgaactgctg tttcccagta acggacttcc caaaacagca
    22681 agggaaagta cagattggtg ggcaaatgat tataaacacc ctgaaaaagg tgcctatggc
    22741 tggataaatg caggctatga agtagttgtc atcaatttgg acaaagaata tgtcgtgttc
    22801 aataaattag tgaaatctag ttggctattt gattaaataa accgcgttta gaaaacgttg
    22861 acaaatttct ttctttttat ataatagagt aacagacgcg aagaaaacgt ttgcgtagtt
    22921 tgttttaaaa aggagagaaa agtatggcta aaaaaacaat catgcttgta tgttcggctg
    22981 gtatgagcac aagtttacta gtaacaaaaa tgcaaaaagc tgctgaagca aaaggaatcg
    23041 actcggatat tttcgctgtg tccgcttctg acgcagataa caatcttgca aataaagatg
    23101 tagatgtact gttattagga cctcaagttc gctttatgaa agctgatttt gaaaaacgtc
    23161 tggaaccaaa aggcattcct ttagacgtca tcaatatggc tgattatggt atgatgaatg
    23221 gcgaaaaagt gttagatcaa gcaatcacgc tcataggtga ataaatagaa cagtataact
    23281 atcgaacaag cgatccaaaa aatagatcgc ttgttttttc gtatattttt ttagggcgaa
    23341 taatatgaat catttttggg gtagaaggct tctgacgaga gatattaaag caatagactg
    23401 tgaggaggta aatttaccaa attatgagaa gatcgcagca gtggaacgtt tgggcaactg
    23461 gattctttgt catcgctgtg gaatgaggac gtccgtcatt gatggacagc ttgcagatta
    23521 cggttatttt tgtacacatt gtctatattt agggcgatgc gacactcaac aagatttata
    23581 tttgtttgat cagcctgaag caaaacctcg agaagtcgtc tttttttgga caggacagct
    23641 tactgaaaaa caaacggaaa tcgcaaagag aatactttgc cattcagaaa aaagacatca
    23701 tcttatttgg gctgtaacag gtgcagggaa aacagagatg ctttatccta ttttagtgga
    23761 aactttaaaa gctggaggaa gagtagcgat ttgtacaccg cgagtcgatg tttgtaatga
    23821 attgttttta cgctatcgtt atgtttttcc agaagaaaaa atcacgttgc tccatgggaa
    23881 tacagcaacg gcttatacct ttacttcttt tgttatctgt acgattcatc agctataccg
    23941 tttttatcgg tcctttgatt taatagtgat cgatgagatc gatgcgtttc cttataacgg
    24001 ggatgcagga ttagctcatg ctgtgcaaac agcgattaaa ccagacggac gattcatcta
    24061 cttaagtgcc acacctgata aaaagttact aaaggaaatc aagcagacgt ttgacatcca
    24121 caaacttgct ttgcgctttc atcggcgttt acttcctgaa cccgtcttgg ttttcatgaa
    24181 taattggcga caaaaatgca agaacaagaa gaagataaaa tctttggtgc ggatcattca
    24241 tcaattaatt aaagaaaacc atatcctttt attttgtcca agtatcacga tgatgcatcg
    24301 tttgaaagcc acacttcaag aggctcttcc gagatatgag atcacagatg tttcttcaag
    24361 agacaatcag cgggcggaaa aagtccagaa aatgcgagaa gcaaaatatg acatactgtt
    24421 aaccacgatg atccttgaac gtggagtcac atttgaaaga atatccgtta tcgttttagg
    24481 agcggatcat ccggttttta ctaaatcttc tttggtacaa atcgcaggaa gagccgatcg
    24541 taaagggcct tatacgaaca gtcaagtata ctttttctat gaagaaaaaa ctgcagctat
    24601 tcgaaaagct tgtcaggaaa tcaaagaaat gaatgaagaa gggaagaaga tgctgtgagg
    24661 tgcagttgct gcagtaaaga tatcgtccaa aatttaacat tcagcgagat tattggtgtt
    24721 tcgaaataca gattacctca gacttgttca gtttgtcgcg cacaatttca tttattggaa
    24781 acaagaggct gttctggctg tcaaaaacca atccatttca atctagagag tacgaaaaag
    24841 aaagtaaagt ctattcccgt ttactgcagt gactgtcaag aatggaagaa gaaatatccg
    24901 acctatgatt ttcagcaccg tgcctttttt gtgtacgatg aaaatatgaa ggcctggctc
    24961 aatcaataca agtttatggg agatatccga ctagcaggca cctttgcata taaatggacg
    25021 cagataaaaa aagaataccc gacatacatc tattgtccaa tacctttatc tgaaaaaagg
    25081 cgaacagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaag aattcctttt
    25141 cagatgctac tcaaaagaga gaagcatctg ctggctcaag caaaaaacac gcgaaaggaa
    25201 agattggaga tgcctcaacc ttttgaactt gcagtcacct tttctaagat acaaaataaa
    25261 aaaatattga ttattgatga tgtctataca acaggacaga ctcttttcca cgcagcagat
    25321 tgtttgcagg tcgcacagcc gaaaatcatc cgaaccattt ctttagcaag atgaattaga
    25381 tgtggaaatt tgatagcgat ttaatttgca aataacctag agttcgatat aatagaatta
    25441 agaagaggga aagagtggtc cttctccttc ttgattgtgg tagacgaaag gggtaatttt
    25501 tatgtttaga tataatgtac gcggcgaaaa tatcgaagta actgaagcga ttcgcgacta
    25561 cgttgagaaa aaagtaggca aactagaacg ctatttcagt gacgcacccg atgcaacggc
    25621 gcatgtgaac ttaaaagttt atacagaaaa aacagcaaaa gtggaagtaa cgatcccatt
    25681 accttatctt gtattacgtg ccgaagaaac ttctccagat ttatacgcaa gtatcgattt
    25741 ggttgttgac aaattggaac gccaaatccg caaattcaaa acaaaaatta atcgtaaatc
    25801 ccgtgaaacg ggcatgaata ctgcagatgc tactgcttta ttcaatgaag aggacgaaaa
    25861 cgaaaatgat tctgaattag atatcgtacg tacgaaacgc ctttcattga aaccaatgga
    25921 tagtgaagaa gcagtcttac aaatgaacat gctgggacat aacttcttta tttttgaaga
    25981 tgcagaaaca aatggtacaa gtatcgttta ccgccgtaaa gatggaaaat acggactgat
    26041 tgaaacagac tgatcagcct tacttaaata acaacgaaaa cttgcagcag ctactgacag
    26101 ctgccgcaag tttttttgag tttcctcctc ttttagatga aatatgaata aattatgaag
    26161 ttcttacttt aatacgctta agatatttca attatctata actaatgata aaatgaaaag
    26221 taaagtctac atagtctgga taatacacag aaggaaaagg agattacaca acgcatggcc
    26281 aatttgattc gttcacttat cgaaaacgat aagaaagaac taaaacgttt agatagcatt
    26341 gcaaaaaaag ttgaagcata cgctgaccaa atggcagcat taactgatga acaattacag
    26401 gcaaaaactg ctgaattcaa gggcagatac caaaaaggag aaacattaga tcaattactt
    26461 ccggaagctt ttgcagtcgt ccgagaagca gcaaaacgtg tattggggtt atatccacac
    26521 cacgtacaat tgatgggtgg aatcgtgctt cacgatggaa atatccctga aatgcgtact
    26581 ggtgaaggta aaaccttgac cgcaacgatg ccagtatatc taaatgctct gactggcgaa
    26641 ggggtacacg tagttaccgt caatgaatat ttagcaaccc gtgactcgac ggaaatgggc
    26701 gaactttata atttcttagg attaacagtg gggttgaata tcaactcaaa atcttcggat
    26761 gaaaaacgcg aggcttataa ttgtgatatc acttatagta cgaataatga attaggattt
    26821 gactacttga gagacaatat ggtcgtttac cgccatcaaa tggtacaacg tccgctgaat
    26881 tatgccattg tcgatgaagt tgactcaatc ttgattgatg aagcgagaac gccgctgatc
    26941 atttcagggc aagcagaaaa atccacagct ttatatacaa gagcagacaa cttcgtgaaa
    27001 cgtttgaaag aagaagaaga ttataaaatc gatgtacaat caaaaacaat cagtttaacc
    27061 gaagcaggga tcgaaaaagc agaagaaaca ttcggtttgg ataacttata cgacattgaa
    27121 aatactgcat tgacccatca cttggatcaa gcattgagag ccaactatat catgctttta
    27181 gatatcgatt atgttgtcca agacggaaaa gtactgattg ttgaccagtt cactggtcgg
    27241 atcatggatg gacgccgtta ttcagatgga cttcaccaag caatcgaagc taaagaaggc
    27301 gtagagatcg aagacgaaac gaaaaccatg gcgacgatca ctttccagaa ctatttccgt
    27361 atgtacaaga aacttgcggg aatgactggt acagctaaaa cagaagaaga agaattcaga
    27421 gaaatttata acatccaagt ataccagatt ccgacaaatc gtccggttat ccgtgatgat
    27481 cgtccagatt tgctttaccc aacattacaa agcaagttcc acgctgtcgt gcaagatatc
    27541 aaagatcgct accgcaaagg tcaacctgtg ttagtcggaa ctgttgcggt tgaaacatct
    27601 gagttattat cagatatgct gaatcaagaa cgtattcctc atgaagtgct gaatgcgaaa
    27661 aatcacttta aagaagcaga gatcatcatg aatgctggtc aaaaaggtgc tgtgacgatt
    27721 gctaccaaca tggctggtcg gggaacagat atcaagttag gacttggggt aagagaactt
    27781 ggtggtctag cagttatcgg gacagaacga catgaatctc gtcgtatcga taaccagctt
    27841 cgaggacgtg caggacgtca aggagaccct ggtatgtcac agttctactt gtcattggaa
    27901 gatgatttga tgaaacgatt cggttcagaa cgaatcaaat ctttcttaga tcggatgaag
    27961 atcggtgagg aagatgctgt tatccaaagc aagatgctga cgaaacaagt agaatctgca
    28021 caaaaacgtg tagaaggaaa taactatgac acacgtaaaa acgtcttaca atacgatgat
    28081 gtgatgcgtg aacaacgtga agtaatctat aaacagcgac aagaagtaat catggaagaa
    28141 aaaagcttat ccaagccact aatgaacatg gtcaaacgga caatcagtcg tgtagtagat
    28201 gcgcatacac aattagagaa agaaaattgg aatttggaaa gtatcatcga ttttgccggc
    28261 agtactcttg tccatgaaga tagtattact cttgcagata tcgaaggaaa aacagctcag
    28321 gagatcaaag agtatctaaa cgaacgagca caagaagtat ttaataccaa agcggctcaa
    28381 ctaaatggtc cagagcaact gttggaattt gaaaaagtcg tgatcttgcg tgttgtggac
    28441 tctaaatgga cagaccatat tgatgcaatg gatcaattac gtcagtcaat cggcttacgt
    28501 gcttatggac agaacaatcc attagtcgaa tatcaaacag aaggctataa gatgtttgaa
    28561 gatatggtag gcgccatcga gtatgaagtc actcgaatct ttatgaaagc tgagatccgt
    28621 caaaacgtac agcgtgaaca ggtttctcaa ggaacagctt ctcactcaga agacggagat
    28681 gccaaagaaa atagtaatac tagcgcgaaa aaacagccaa tccatgtgaa caaggtcgga
    28741 agaaatgatc cttgtccttg tggaagcggg aaaaaatata agaactgtca tggaaaaaat
    28801 gcaaactaat ttctgacagc aggattggtg agacaaattc tttttttaag aattcgtctc
    28861 accttctttc tgttatttgc tgattctgtt agactagata taatgaaaaa agtatagtga
    28921 aagaaggaaa aaacatggaa atatccgaaa ttcgaaatct cctgacagaa atgcaggaaa
    28981 aggtcacaag cttcaggagg tctctttgac ttagaccagc tggaagaaga cattgcggaa
    29041 gcagaagcaa aaatggctga acctggtttt tgggatgata gcgaagctgc tcaaaaagtg
    29101 atcagtgaaa acaatgcaaa taaagaaact tatgatcaat tccattctct tgctgaagaa
    29161 ctggaagaaa tcgaattgat ggtggagatg ttgcaggaag aacctgatgc agccatgcaa
    29221 gaagaagcag aaacacgtat caatgcgcta gatgaaaaaa tgaagacata tgaattatct
    29281 atgttgttag atggtcctta tgatcgaaac aacgccatcg ttgaattgca tccaggggct
    29341 ggcggaacgg agtcccaaga ttggggcagt atgcttttac gtatgtatac acgctgggca
    29401 gagcagcatg ggtatcaagt agagacacta gattatcaag caggtgatga agcaggaatc
    29461 aagagtgtga ccctactgat caaaggacac aacgcatttg gttatctgaa atcagaaaaa
    29521 ggtgttcatc gccttgtacg tatctcgcct tttgactcag cgaaacgacg tcatacttct
    29581 ttttgttcgg tagatgtgat gccagagctt gatgaaacga tcgatataga aatcaatcca
    29641 gatgatttga aaatcgatac gtaccgagca agtggtgcag gtggtcagca catcaataaa
    29701 acagaatctg ctgtacggat cactcacttg cctacaggaa cagtagtagc tagtcaggca
    29761 caacgttcac aattgaaaaa ccgtgagcaa gcgatgggga tgttaaaagc taagctttat
    29821 caattagaag tggaaaagaa agaacaagaa gcagctgcac ttcgaggaga acaaaaagaa
    29881 atcggctggg gttcacagat ccgttcttat gttttccatc catattctat ggtaaaagac
    29941 catcggacaa acgtagagac aggaaatgtc caagcagtta tggacggtga ccttgattta
    30001 tttattgacg gctatttaaa aatgcatcta caataagaac ccattgttaa attgaaataa
    30061 aattgtaaga ttttgcaagc atgttgaaac attgccatgc tataatagct aaagactgaa
    30121 aaagatatgg agagaacgcc atgattgaaa tgaaggatgt aatgaagaag tactcaaatg
    30181 gtacgaccgc tatccgcaat ctctcaattg tcatcgaaca aggagagttt gtctatgtgg
    30241 ttggtccgtc tggagccggt aaatctacat tcatcaaatt gatgtatcga gaagaaaaag
    30301 cttcaaaagg aactttgaac gtcgcaggtc atgatctaat agcaatcaaa aaccgcgaag
    30361 ttccttatct acgcagagaa atcggcgtgg tgttccaaga ctataaatta ttaccaagaa
    30421 aaacagtata tgaaaatgtt gcgtacgcta tgcaagttat cggcagaaaa cctcgggata
    30481 tcaaaaaacg agtaatggaa gtgctggacc ttgttggttt gaaacacaaa gttcgagtct
    30541 ttcctagcga attatccggt ggggaacagc aacgtgtctc tattgctcgg gcaatagtga
    30601 atacgcctaa agtacttatc gcggatgaac cgacaggaaa tctggatcca gaaaactcat
    30661 gggaaatcat gaaattatta gatcggatca atgcccaagg aactactgtc gtgatggcta
    30721 cacataacag tacgatcgta aatacgattc ggcaccgagt aattgctatc gaaaacggcc
    30781 gcattattcg agatcaagcg gaaggggaat atggatacga tgattagaac ctttttccgc
    30841 catttattag aaagtatcaa gagtttgaaa cgtaacggct ggatgacagt tgcttcagtc
    30901 agtgcggtaa cgatcacatt gactttagtc ggtgtattca tggcagttat catgaacgca
    30961 actaaattag ctcaagatat agaaggaaac gttgatgtct ctgtattcgt agatatcggt
    31021 acaaaagacg aagagatgaa aaagctagaa aaagaattga atgacttaga tcatgttaaa
    31081 aaagttgaat tttcaagcaa agaacaggaa ttgaaaaaaa tccaaaacga aatgggtgat
    31141 tcctggaaat tgtttgaagg tgacaataac ccgttatatg atgtgtatgt agtaagtgct
    31201 actgatcctt cttatacaaa acaagtagca gaagaagcag cagatttgaa gaatgtttct
    31261 cgttctgatt acggtggagc ttcctcagat cggattttcc aaatcgctgg tgcagttcgg
    31321 acatggggat tagttgcagc ggcattgctg ctgttcgtag cgatgtttct catttcgaac
    31381 acgattcgga tcacgatttt gtctagacag cgtgaaattc aaatcatgcg tttagtcggt
    31441 gcaaaaaatg gatatattcg ctggccgttt ttccttgaag gtggctggat cggtctgatc
    31501 ggtgcgattc ttccgatttt gatcatcaca tttggttatg catggttttt ccaattgatc
    31561 aatccatcat tattacgttc ccattattca ttgattcatc cacaaaatat cgtttggaaa
    31621 atcaatcttt taatggtcgg cattggtgtg atcattggtt cacttggctc gatcatttct
    31681 atgagacgtt tcttgaaatt ctaataccac aatataaata aaatgagaaa gttggacagt
    31741 ttcgttccag ctttcttttt ttattggcta ggagaataga aggaagcggc ttttttccct
    31801 ttactttaaa aaacaacttg ggtattctta agttggtaga agaagaggtg aagccgtgaa
    31861 aattatcgtt gacaattttt ttacgatcct tttgattatg aatattttgc tttcctttat
    31921 catcgttttt cgagaaagaa aggaaactgc tcaaacatgg gcatgggtgc tcgttttgat
    31981 gttcattcca gttgtaggat ttattttata tattttttta ggaagaggga tttccaaaga
    32041 gaaaatcttt gatttgaaga tccaagggaa aatcggtaag aacctggaaa ttgaagaaga
    32101 caaacaggca ttgatgcgag ggctttatcc tcatccgcct actggacaag tagatgtgaa
    32161 acaattgatc tatatgctca cggtatttga aagtacgctc tatacgacta aaaatgaaat
    32221 cactttattt acagatggtc gtgaaaaatt cgatgcgctg attgaagata tcaagcaggc
    32281 agaagaccat atccacttcc agtattatat ttatcgcagt gatgcattag gtgaagaagt
    32341 tcgagatgca ttgacagagg cggcaagacg aggggtaaaa gtcagagtcc ttcttgatgc
    32401 atggggttcc acacaagttt cttccagctt ttttcagaat ttgaaaaaag caggcggaga
    32461 agtcgcattt ttctttcctc tatttgttcc gtatattaat cctcggatca attatcgcaa
    32521 tcatcgtaaa atcgtagtta ttgatgggaa aatcggatat acaggtgggt tcaatgttgg
    32581 aaatgaatat ctaggattgg taaagaaatt tggttattgg cgagacaatc atttgcgtat
    32641 ttacggagaa gcggtgtata ccttgcaaaa ccgttttttg atggactgga attctcagca
    32701 tacaaaagaa gtaggctatt ctcccaaatt ttttccgtcc attcactcta ctggtgatat
    32761 agctgttcaa atcgtgacaa gcggaccaga taccgaacat gaacaaatca aaatgactta
    32821 tttgaaaatg atttcgttag ccaaacggga gatattgatc caaacgcctt attacatacc
    32881 ggatggatcg attcatgaag cactgaagtt ggctcttctt tcaggcgtaa aagttcatat
    32941 ccaaatacct aacaaaccag atcatcttct cgtttactgg gcaacgtatt ctttcgctgc
    33001 agagctaatc gagtatggag caaggatcga aacatatgag aatggattta ttcatgcaaa
    33061 gacgatgatt atcgatggtg gcattgtttc agttggctca gcaaatatcg atgttcgttc
    33121 atttcgcttg gactttgagg tcaatacact ggtttatgat gaacgaatgg cttcacgtgt
    33181 aagaaaagct ttttttgaag actcgaaaat ttctacgcat ctcacaaaag aaatgtatga
    33241 aaaccgagga ataatcatca agatgaaaga aggattagca agattgattt cgccgctcct
    33301 ttaaaacata aaaaggacat gagaaccatc aacagatgga gatctcgtgt ccttttctaa
    33361 cggggccatt tctgagagta cgtcagaaat ggagaaagcg tctcgcatga gcgaaattaa
    33421 ctttggggta tctcttgttt tttggggaaa gcaagaaata agctaatata tgctattaaa
    33481 agagacacat ttcaaagcca gtatagcata gaaactttta atgagatagt tttttttaca
    33541 attatgagaa tttattttgt tatttaatga ttttgattcg ttttcatcaa gtaatgaaaa
    33601 tgataaaata aacatacttt aggattaaag gagatttcta atgaaaaaac ttaaattatt
    33661 cttaccaata ataggattag ctattctttt atcaggctgt tcaaagtgga ttgatcgagg
    33721 agaatccatt acggctgttg gctcttctgc tttacagcct ttagtagaaa cagttgctga
    33781 aacttaccag acagaaaatc ctggaaaatt catcaatgta caagggggcg gaagcggaac
    33841 tggtttgtct caagtacagt caggagcagt cgacatcgga aactctgatt tgtttgcgga
    33901 agaaaaatcg gggatcgatg cctcagcatt agtcgatcat cgagtagcag ttgttgggat
    33961 cactcctatt gtgaacaagg atattggcgt aaaagacatc agtatggaaa acctgaaaaa
    34021 actatttaca ggcgagatca aaaactggag tgaagtcggt ggaaaagatc agccagtagt
    34081 tatattgaac cgcgcttcag gaagcggaac ccgtagcacg tttgaaaaat gggtattgga
    34141 cggagaaaca gctgttcagg cacaagaaca agattcaagc ggaatggtgc gccagatcgt
    34201 tgccgacaca cccggtgcaa tcagctatgt tgctttttct tatgtttccg atgatgtaga
    34261 tacgttgaat gttaacggtg tagaaccgac agatgaaaat gtgacaacga acaaatggac
    34321 gatttgggca tatgagcata tgtacacaag agatcatcca aaaaaactga caaaagaatt
    34381 tttagactat atcttatctg atgaagtaca agataacatc gttggagaac taggttatat
    34441 ccctgtttct catatgaaag tcgaacgtga ttggcaagga aatatcgtta aagagtaatc
    34501 tttacacaaa atttacaaac ttagctaaac ttttacatgt tattaaaacc aaattgatgt
    34561 tcaatttgta cactgagtga gtatgttaaa cctgattaag ggggagtcat ctgtggaaga
    34621 tgtgaaaaaa gtattattaa caaaatcaaa acgttcaaaa atggaacagc gtggaaaatt
    34681 catcagtttt ttatgtatcg cgctgatcgt gttggttgta ttatctattt tttattttgt
    34741 agctagtaaa ggattggcca ccttttttac tgataagatc aatgtatttg attttctgtt
    34801 tggtacagat tggaatccaa gccaaatcgg agcaaatggg aaaccaatgg taggggcatt
    34861 gcctatgatc acaggttcgt ttattgtgac ctttttatct gctatcgttg ccacgccatt
    34921 tgccattggt gcagcagtat tcatgacgga gatctctcct aaaaacggaa cgaagatctt
    34981 acagccggtc atcgagctgc ttgtaggtat tccttctgtc gtttatggtt ttatcggttt
    35041 atcagttatc gtgccttttg tcagaagtat ttttggcggg actgggtttg gtatcttagc
    35101 tggtacattt gtgttgttcg ttatgatctt gccgactgtc acaacgatga ctgttgatgc
    35161 attaaaggca gtgccacggc actatcggga agcttcatta gcgcttggtg ccacaagatg
    35221 gcaaacaatc tacaaagtcg tgctacgagc agccgtgccc gggattttaa cagcagtcgt
    35281 ttttggtatg gctcgtgcgt ttggtgaagc cttagctatc caaatggtca tcggtaatgc
    35341 agcattgatg ccaacaggtc ttactactcc tgcttctaca ttgacgtcca tcttaacaat
    35401 gggaatcgga aatacaatca tgggaacagt tgaaaataat gtgttatggt cattagcgct
    35461 gatcttgcta ttgatgtcat tattctttaa tatcgtgatc cgtatgattg ggaagaaagg
    35521 agagctgaaa taatgaacgc aaaacgctca gataaaattg ctacaggtgt tttatatata
    35581 gtttcgggga tcatcgtatt gattttagca gctttactac tttatatctt agttcgggga
    35641 ataccgcaca tttcatggtc cttcttgacc gaaccttcca aagcctacca agaaggcggt
    35701 ggaatcggga tccagctatt taactcgatt tatttgcttt tgatcacgat gatcatcagt
    35761 tttcctattt ctttaggtgc gggtatctat ctttcagaat atgctggaaa aaactggcta
    35821 acagatgtga ttcgcacgtc gattgaaatc ttgagctcgt tgccttctgt cgttgtcggt
    35881 ttattcggtt tcttggtttt cgttattcaa ttccagtatg gtttctcgat tatttctggt
    35941 gcattggctt tgactgtatt caacttgcct cttttgacta gaacagttga ggagtcttta
    36001 caagcggtcc attacacaca acgagaagca ggattggcct taggtttgtc acgctgggaa
    36061 acagtgataa aagtggtggt tccagaagcg acaccaggga ttttgactgg tgtgatccta
    36121 agttctggaa gaatttttgg tgaagcagct gcattgatct atacggctgg acaaagtgca
    36181 cctgcgttag attttacgaa ctggaatcca ttaagtgttt caagcccgat cagcattttc
    36241 cgtcaagctg aaacattagc tgtccatatt tggaagatca atacagaagg cacgatgcct
    36301 gatggtgttt ctgtttcggc tggcgcttct gccgtgttga ttattgctgt tttactgttc
    36361 aacttcggcg ctcgtgcgat tggcaaacga ttataccgaa aaatgacttc agcctaagga
    36421 gaagaagcaa aatgaaaaaa tataactgga atgaaacaaa tgtcatcacc atgccaaaag
    36481 agaaagaagt agcactatat acggatgatc tacatgtctg gtatggcgac aatgaagcaa
    36541 tcaaaggagt ggatctggaa tttgaaaaaa ataagatcac tgcactgatt ggtccttccg
    36601 gctgcggaaa atctacgtat cttcgttcgt tgaatcgaat gaatgatggg atcgctaata
    36661 cgaaaatcac tgggaaaatc atgtatcaag gcgtagatat taatgcgcct caagtggatg
    36721 tttatgagat gcgcaaacgg attggcatgg tttttcaacg tcctaatccg ttcagcaagt
    36781 cgatttatga caatattaca tttgctttga aacagcacgg cgaaaaaaac aaaaagaaat
    36841 tagatgaaat cgttgaaaca agcttgaaac aagctgcctt gtgggaccaa gtaaaagaca
    36901 gcttggacaa aagtgccttg gctttatctg gcgggcaaca gcaacgttta tgtattgctc
    36961 gtgcgatcgc gatgaaacct gatatcttgc tgctagacga gccggcaagt gctttggacc
    37021 ctatttcgac aggaacggtt gaagaaacac ttgtaaactt gaaagaagac tatacgatca
    37081 tcatcgtgac gcataacatg caacaagcag ctcgtatcag cgactatact gcctttttct
    37141 atttaggaaa agtaatggaa tatgacaaaa ctaacaagat atttaccaga ccaaaaattc
    37201 aggcaaccga agattatgtg tccggtcatt ttggttaaga cggaggcctc aacatgacaa
    37261 aagagattat ttcatctaaa gatcttcatc tgtattatgg aaagaaagaa gcactaaaag
    37321 ggatcgatct aagcttcaat caaggggaaa tcactgcgat gatcggtcct tctggttgcg
    37381 gaaaatccac ttatctgcgt tctttgaacc ggatgaatga cctgattccg aatgtaacga
    37441 tcaccggaag tgttttatat aaagacaaag acatctatgg tccaaaaaca gatgttgttg
    37501 aactaagaaa agaaatcggc atggtattcc agcagccaaa cccatttcct ttttctatct
    37561 atgaaaatgt catctatgga ttgaaattaa aaggggaaaa agataaaaaa gtccttgatc
    37621 aagtagttga agaaagcctg aaggcagcgt ctgtttggga tgatgtgaaa gacaaattgc
    37681 ataaaagtgc tttatcttta tccggtgggc agcagcagcg tgtatgtatc gcacgtgttt
    37741 tggcagttaa tccggaaatc atcttattgg atgaaccaac aagtgcgctt gatcctgttt
    37801 ctactgggaa aatcgaaagt atgctgttag aattaagaga gcggtatacg atgatcatcg
    37861 tgacccataa tatgtctcaa gcttcacgta tttcagataa gacggcattc tttttagatg
    37921 gtcacttgat cgaatacaat gatacgaaga agatattcat gaatccagaa aaacaagaga
    37981 cagaagatta tatttcaggt cgatttggat aaggaggaaa cggaatgcta cgtacacaat
    38041 ttgaagaaga attgctgaat ctccataatc agttctacga aatggggatg atggtgagca
    38101 gcgccgtgca caagtcagtt cgtgcataca tcaaacacga taaaatctta gcccaagaag
    38161 ttatcgaaaa cgatataaat atcaataaca tggaaacacg cttggagaag aaaagttttg
    38221 aaatgatcgc attgcaacag ccagttacaa ctgatttgcg tatgatcatt acggtcatga
    38281 aagctagctc ggatttagaa cgtatggccg atcatgcggt gtctgttgct aaatccacga
    38341 ttcgcgtaaa agggcagacg agaataccgg aaatcgaaaa agagatctcc gatatgtccg
    38401 attatgtgaa aaaaatggtg gacaacgtcc tagttgctta tgtcaaaaca gacgaaaaag
    38461 acgcacgtac gatcgccaat atggatcaaa gagtcaatga ctatttcaat cgaatctata
    38521 atgcaacaat caaaaatatg caggaaaatc ctgagacagt catcagtgga acagactact
    38581 tgaatgttgc cagttatcta gaacggatcg gagactatgt gacaaacatc tgtgaatgga
    38641 tcgtctactt ggctacaggg aaaatcactg agttaaatac gaaccacaat gagattttct
    38701 aaactgaagc tgtgattatg ccgtttgttt aggaaaagag gttgtgaaat cagcggttgt
    38761 gaaaaagctg ttctgcatca agtaataaga acagtcaaac aaaaaatagc tcctcatatt
    38821 tttcgtttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgggaa
    38881 agggtttgtg acaaaacatg tcacaaaccc tttt
//
LOCUS       DASHWW010000019        37078 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.019, whole genome shotgun sequence.
ACCESSION   DASHWW010000019 DASHWW010000000
VERSION     DASHWW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.019"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            100..531
                     /gene="mraZ"
                     /locus_tag="U2R64_001142"
     CDS             100..531
                     /gene="mraZ"
                     /locus_tag="U2R64_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HEM8917974.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            552..1511
                     /gene="rsmH"
                     /locus_tag="U2R64_001143"
     CDS             552..1511
                     /gene="rsmH"
                     /locus_tag="U2R64_001143"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEM8917975.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1516..1917
                     /gene="ftsL"
                     /locus_tag="U2R64_001144"
     CDS             1516..1917
                     /gene="ftsL"
                     /locus_tag="U2R64_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEM8917976.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1918..4110
                     /locus_tag="U2R64_001145"
     CDS             1918..4110
                     /locus_tag="U2R64_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEM8917977.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4136..5098
                     /locus_tag="U2R64_001146"
     CDS             4136..5098
                     /locus_tag="U2R64_001146"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEM8917978.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5112..6473
                     /locus_tag="U2R64_001147"
     CDS             5112..6473
                     /locus_tag="U2R64_001147"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEM8917979.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6499..7587
                     /gene="murG"
                     /locus_tag="U2R64_001148"
     CDS             6499..7587
                     /gene="murG"
                     /locus_tag="U2R64_001148"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HEM8917980.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7602..8822
                     /locus_tag="U2R64_001149"
     CDS             7602..8822
                     /locus_tag="U2R64_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEM8917981.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            8978..10303
                     /gene="ftsA"
                     /locus_tag="U2R64_001150"
     CDS             8978..10303
                     /gene="ftsA"
                     /locus_tag="U2R64_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEM8917982.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10326..11567
                     /gene="ftsZ"
                     /locus_tag="U2R64_001151"
     CDS             10326..11567
                     /gene="ftsZ"
                     /locus_tag="U2R64_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEM8917983.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11584..12261
                     /locus_tag="U2R64_001152"
     CDS             11584..12261
                     /locus_tag="U2R64_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEM8917984.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12275..12874
                     /locus_tag="U2R64_001153"
     CDS             12275..12874
                     /locus_tag="U2R64_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEM8917985.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12889..13176
                     /locus_tag="U2R64_001154"
     CDS             12889..13176
                     /locus_tag="U2R64_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEM8917986.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13225..14007
                     /locus_tag="U2R64_001155"
     CDS             13225..14007
                     /locus_tag="U2R64_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEM8917987.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            14028..14735
                     /locus_tag="U2R64_001156"
     CDS             14028..14735
                     /locus_tag="U2R64_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEM8917988.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            14997..17795
                     /gene="ileS"
                     /locus_tag="U2R64_001157"
     CDS             14997..17795
                     /gene="ileS"
                     /locus_tag="U2R64_001157"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEM8917989.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(17844..19370)
                     /locus_tag="U2R64_001158"
     CDS             complement(17844..19370)
                     /locus_tag="U2R64_001158"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEM8917990.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(19385..20032)
                     /locus_tag="U2R64_001159"
     CDS             complement(19385..20032)
                     /locus_tag="U2R64_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEM8917991.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(20216..20545)
                     /locus_tag="U2R64_001160"
     CDS             complement(20216..20545)
                     /locus_tag="U2R64_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HEM8917992.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            20722..21450
                     /gene="sfsA"
                     /locus_tag="U2R64_001161"
     CDS             20722..21450
                     /gene="sfsA"
                     /locus_tag="U2R64_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HEM8917993.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            21466..22479
                     /locus_tag="U2R64_001162"
     CDS             21466..22479
                     /locus_tag="U2R64_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8917994.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            22479..23756
                     /locus_tag="U2R64_001163"
     CDS             22479..23756
                     /locus_tag="U2R64_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEM8917995.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            23819..26521
                     /locus_tag="U2R64_001164"
     CDS             23819..26521
                     /locus_tag="U2R64_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8917996.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            26673..26990
                     /locus_tag="U2R64_001165"
     CDS             26673..26990
                     /locus_tag="U2R64_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8917997.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            27020..27340
                     /locus_tag="U2R64_001166"
     CDS             27020..27340
                     /locus_tag="U2R64_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEM8917998.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            27448..28908
                     /locus_tag="U2R64_001167"
     CDS             27448..28908
                     /locus_tag="U2R64_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8917999.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            28976..29197
                     /locus_tag="U2R64_001168"
     CDS             28976..29197
                     /locus_tag="U2R64_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918000.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            29228..29410
                     /locus_tag="U2R64_001169"
     CDS             29228..29410
                     /locus_tag="U2R64_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HEM8918001.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            29410..29823
                     /locus_tag="U2R64_001170"
     CDS             29410..29823
                     /locus_tag="U2R64_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEM8918002.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            29946..31127
                     /locus_tag="U2R64_001171"
     CDS             29946..31127
                     /locus_tag="U2R64_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918003.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(31198..31362)
                     /locus_tag="U2R64_001172"
     CDS             complement(31198..31362)
                     /locus_tag="U2R64_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918004.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            31516..31589
                     /locus_tag="U2R64_001173"
     tRNA            31516..31589
                     /locus_tag="U2R64_001173"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31550..31552,aa:Arg,seq:cct)
     gene            complement(31658..32797)
                     /locus_tag="U2R64_001174"
     CDS             complement(31658..32797)
                     /locus_tag="U2R64_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8918005.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(33096..33731)
                     /locus_tag="U2R64_001175"
     CDS             complement(33096..33731)
                     /locus_tag="U2R64_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918006.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(33844..34479)
                     /locus_tag="U2R64_001176"
     CDS             complement(33844..34479)
                     /locus_tag="U2R64_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HEM8918007.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(34513..34974)
                     /locus_tag="U2R64_001177"
     CDS             complement(34513..34974)
                     /locus_tag="U2R64_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HEM8918008.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(35104..35535)
                     /locus_tag="U2R64_001178"
     CDS             complement(35104..35535)
                     /locus_tag="U2R64_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEM8918009.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(35553..35873)
                     /locus_tag="U2R64_001179"
     CDS             complement(35553..35873)
                     /locus_tag="U2R64_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918010.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            36172..36948
                     /locus_tag="U2R64_001180"
     CDS             36172..36948
                     /locus_tag="U2R64_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEM8918011.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
BASE COUNT        12342 a         6338 c         7578 g        10820 t
ORIGIN      
        1 aataaaaaaa gttgttcccg gatttcccag aaaaggtggt agaaagtggg ggattgtggt
       61 agactaattt tagttagtgg aggaatgggg gggctttcaa tgttgatggg tgaattccaa
      121 cataatattg atgcaaaagg acgtttaatc gtgccctcaa aacttcgtga agaacttggc
      181 gaaaagtttg ttctgacacg cggattggat ggctgtcttt tcggctatcc gatgagcgaa
      241 tgggaaaatc tggaagctaa actgaacgaa atgccgttgg ctaaaaaaga cgcacgtact
      301 tttgtgcgat tcttctattc ggctgccact gaatgcgaac ttgataaaca aggacgaatc
      361 aatataccca gcacgttaag aaattatgca gctttgacaa aaggttgcgt agtcatcggt
      421 gtatctaacc gaattgaaat ttgggatgag acacgatggc aagatttttc tgcagcagca
      481 gaagagaact ttgacgaaat tgctgaaagt atgattgatt tcggactata agaataggaa
      541 gaggctgact aatgactgaa acatttcaac actatacagt catgttgaaa gaaacggtag
      601 atggattgaa catcaaaccg gatggcgttt atgtagactg tacactcggc ggtgccggac
      661 atagtgaata tttattaagc caactaagtt ctaaagggca tctgtatgcg tttgaccaag
      721 atcaaaaagc aatcgatcac gccaagctgc gtttagcttc ttatgtcgaa caaggtatgg
      781 tcacatttat caaagcgaac ttcagagaat tagaagaacg cttgagtgag catgtagata
      841 aggtagacgg cattttgtat gatctagggg tttcctctcc tcagctagat gaagcagaac
      901 gtggatttag ttatcatcaa gatgcaccgt tggatatgcg catggatcag tcagctcctt
      961 tatccgctta tcacgtaatt aatgaatatt cctaccatga attagtaaag attttcttcc
     1021 gctatggcga ggagaaattt tccaaacaaa ttgctcgtga aatcgaacga gtacgaaaaa
     1081 caaaaccaat ccaaacaact ggtgagcttg tcgaaatcat taaacaagtc atcccagctc
     1141 ccgcaagaag aaaaggcggg catcctgcaa aaagaatttt tcaagctgtg cggattgcag
     1201 taaatgacga actcggtgcc gaagaggcct ctttagaaca ggcaatccgg ttattgaaag
     1261 tcaatggaag aatcagcgta atcacattcc attcattgga agacagaatt gtcaaaagta
     1321 tgtttaaaga atatagtacg gtacaagatc taccaccggg acttcctgtc atacctgacg
     1381 aattccaacc agaactgaaa gtcattactc gtaaaccaat ccttccttca gaggaagagc
     1441 taacagaaaa caatcgatca cgcagtgcaa agttacgtat tgcagaaaaa ataagaatga
     1501 aagaggagta gaatgatggc agaattaaag aaaatgcaag attacgaata tgatttacct
     1561 gaattggtgg atcagccgga acaacaaatg cctgattctt cttcgaatca agaaatcatt
     1621 cttccacaat caccggcaaa acgattaaag cagatttctg ctttggaaaa aattgctgtg
     1681 gcaagcgtgg cgattgctat tgttgcttta tgtgttttaa cagttatgct gcgcacaaat
     1741 atcagcggag ctgaaaaaga aatcacgtca atacaaacag aaatcaatga taaaaagcaa
     1801 gaaaaaacga gtttagaaca agaaaaaaac gaactttctc gtactgaacg gattaaacaa
     1861 atcgcagaag aaaaaggatt gtctattaat gacgacaatt taaggaaagt gaagtaaatg
     1921 agtcttaaaa ataaaattcg gcggtttatg gaaaagaaaa atctaaatcc gataaacaat
     1981 cgcaaaaaag taggtatcat tttatttgct acgagtattg gattgttctt tttatttgcc
     2041 gtccgtttct cgtatatcgt tattggaggt catgttgctg gtacctcatt agctgaaaaa
     2101 acaaaacagt tgtaccaagg aagtgaagta gtaaaagcaa aaagaggaac gatttatgat
     2161 cgtaacggtg tggcgctcgc agaagatgcc tcctcttatt caattaaagc gatactctca
     2221 aaaacatata cctctgggga taaaaaactg tatgttgaag aaaagaattt tgataaaata
     2281 gcagaaatcc tgcataagaa tctttctata gacaaaaaag atgcactgaa tattttagag
     2341 gacggcgcaa aaaaagagct gtatcaagtt gaatttggta gctatgggaa aaatatctcc
     2401 caagaaacca agcaaaacat cgaagcggac atgaaaaaag aaggtgtcgc tggtctttat
     2461 tttgtcgacc atcaggctcg gatgtatcca aatggcgtct tttcttctca ttttattgga
     2521 tacgcagttc cagacaaaga tgagaatggc ttagttggta aactaggttt ggagtctgct
     2581 tacaatgata tcttgagcgg taaagatggt aagattattt atcaaaaaga taattttcaa
     2641 aatcctctgc caggtacagt ggcagaagaa gaaaaagctg tcgacggaca agatatctac
     2701 acgactttag acagcagact acaaagttat ttagaaacac tgatggatca agtaaatgaa
     2761 gaatatcagc cagaagaatt gacagcagtc ctgatgaaag caaaaaccgg agaaatcttg
     2821 gcaatgggac aacgacctac tttcaatcct gaaacaatgg aaggattgac tggaaaagat
     2881 gctatctggc gtaatttctt ggtacaagat agttatgaac caggatcaac catgaaagtt
     2941 ttcactactg cagctgctat cgaagaagga gaattcaacg agaatgaaac cttccaatct
     3001 ggaaaaatcc aagtagaaga tgctacgatc aatgaccatg actttggtga aaaaggtgtg
     3061 ctgaccatgc gtcaagctct ttcatggtca agtaacgtcg ggatggtcat actggaacag
     3121 cgattaggcg gacgatggta taactattta caaaaactgg gatttggaca aagtactcat
     3181 tctggattag atgatgaagt aaacggtgct ttacctacat taaatattgt cgaccgagca
     3241 atgagtgctt atggacaagc ggtaggtgtg acgaatttcc aaatgatgaa agctttcact
     3301 tctattgcga ataacggtac aatgattcaa cctcgatata tcagcaaagt ggtggatccc
     3361 caaactggag aagagcgaac aactcaaaca gaagttctag ggcaaccttt ttcaaaagaa
     3421 acaacagaaa aagtccgtga atatatgaga gatgttgtcg aaagcgaaaa ctacggtagt
     3481 gcttatggtg tatatagtgt acctggatac aatgtatcgg caaaaaccgg aacagcccaa
     3541 atcgcttctg atacaggggg atatcaaaca ggagatacag cctacctgta ttcgattgtg
     3601 gagatggttc cttctgaaga tccagactat gtcttgtatc taacaatgaa acaccctaag
     3661 acatatgatc gaatggcatt ggctaaaatc gcaaatccat tgatgaaacg ggcaatggat
     3721 tttaaagaaa ctgaagaaga ttcagataca gaaacaaaaa cagaaaaagt atccgtagcc
     3781 gattatcgta atcttgaagc ggacgttgca gcagctgatg ctcaaaaaag tggactgcaa
     3841 cctgtagtga tcggtaatgg taaaaaagta caaaaacaat ctactgccaa cggtgatcag
     3901 ttgatctctg gagaaaaact gatcctatat actggtggtg ataagctgat gcctgacgta
     3961 acaggatggt caaaagcaga tatcatgaag ctggggaaaa tcctcggtat tgaagttagt
     4021 tttgatggag atggttattg tgtcaaacaa gaacttgctc catatgaaaa aatcactgaa
     4081 gacaaactta gttttacttt agaagaataa gaagagaaat aggagagaaa agagcatgga
     4141 atggacacaa gcattgattc ccattgtcag cagttgtgca atgacaattg ccgcaatgcc
     4201 gctatttatt ggttattttc aaatgaaaaa gcaaggtcag gcgattcgtg aggagggacc
     4261 aaagtggcac aatagcaaag ccggaactcc tacaatgggc ggcttagtgt ttctgatcgg
     4321 ctctattttg acaggaattt gggttggagc ttggcaaaaa cagctaactc ctactctttt
     4381 catcttgctt tttgtattag cgttatacgg agtaatcggc tttcttgatg attttataaa
     4441 aatattcaag aaaagaaaca tgggactgaa ctcgaagcag aaattgattg gacagattct
     4501 agggggaatc atcttttatc ttgtttaccg ttctgaaggt tatccaggtg tattgaattt
     4561 cttcggacta gatctacctt taggaatcat ttatggtatt ttcgctctct tctggcttgt
     4621 tggattttca aatgcagtaa atctgacaga tggcatcgat ggattagttg ctggcttagg
     4681 aagtatctct tttgcagctt acggtctaat tgcttggcat cagcatcagt atgatgtatt
     4741 aatcatttgc ttaagtgttt taggaggttt actgggtttc ttcgtctaca acagaaaacc
     4801 tgccaagatt tttatgggag atgtcggttc attagcgttg ggcggacttt tagcggcaat
     4861 ttctataatg ctaaaccaag aatggacatt gcttttgatt ggtttgatct atgttatgga
     4921 aacagcaagt gtgatgcttc aagttacttc ctttaagctt acaggaaaac gaatttttaa
     4981 aatgtctcca attcatcatc actttgaaat gtgcggatgg tcggagtgga agattgatac
     5041 agttttttgg ttgatcagca ttgtgacttc gttgatcaca ttatggatcg tttggtagga
     5101 gatgacggga aatgaaaaaa atatcaacat atgaaaataa gaaagtgctt gtcttaggac
     5161 tcgcaaaaag cggagtaagt gcggccaaat tattacatga attgggcgca cttgtcaccg
     5221 ttaatgatgg aaaacctttt gacgaaaatc cggaagcaca agagctgctt tctttaggga
     5281 taaaagtaat aacaggtagt catccaatcg aattgttgga tgaagaattt tcattgatgg
     5341 tcaaaaatcc agggattccc tacagtcatc ctttagtagc aaaagcccaa gaaatgggta
     5401 ttccggtaat tacggaagtt gagctagctt acgaagtagc ggaatgccca attattggga
     5461 ttacaggaac gaacggaaaa acaacgacaa caacgatgac aggactacta ctgaatgcag
     5521 gagcagatca aggaattgca cgtttagcgg gtaatattgg gtatccagca agtggtgtag
     5581 cgcaagaagc aaaatcagaa gataaaattg tgatggaatt gtctagcttc caactcatgg
     5641 gaatcacaga tttccgccct catatagcgg tgattaccaa tatctatgaa gcacatattg
     5701 attatcatgg tacaagaaaa gaatatgtca aagctaaatg gaaccttcaa aaaaacatga
     5761 cagaaaaaga ttatctgatc cttaactgga atcagtcaga actacaagaa ttagcgcaaa
     5821 gaacaaaagc acgcgtactg cctttctcga caaaagaagt gttggaagac ggtgtgtatg
     5881 ctgacgatta ctcaatatac tataaaaaag aaaaaataat ggaaatatct gaacttggcg
     5941 taccaggtaa gcataatgta gaaaatgcac tagctgctat ttctgtagca aaattgtatg
     6001 gtatatcaaa tgaagctata cgagaaacgt tgcatttttt ccatggcgta ccacatcgta
     6061 cgcaatatgt aggagaaatc caaggcagaa aattttataa tgattcaaaa gcaaccaata
     6121 ttttagcgac taaaatggct ctaagtggat ttgaaacgtc taaggtcgtg ttattggctg
     6181 gcggattaga cagaggaaat acatttgatg aattaattcc ttcattaaaa ggaatcaaag
     6241 caatggtcgt atttggccaa acaaaagaaa agttgatgga tgctggaaaa aaagcaggca
     6301 tcgagacaat agtaacagcc gattctgtag aacaagcagt tcctttagca ttagaaaaca
     6361 gtacagatgg tgatgtagtt ttattatcac cagcgaatgc cagctgggat caatacccaa
     6421 attttgaaac tagaggaaac agattcatgg aagctgtgaa ccgattaaaa tagaaaaagt
     6481 agaagcgagc gataaaaaat gaaaattttg gttacaggcg gaggaacagg gggacatatt
     6541 tatccagctc ttgcctttgt caattatgta aagactcaag aaccgaatgc tgaattcatg
     6601 tatgtgggag caaaacgagg tctagaaaac aaaatcgtcc ctgatacagg aatgcctttc
     6661 cataccttgg agattcaagg atttaaacga aaaatttcca tgcataacat caagacggtc
     6721 cgattgtttc ttaagagtat ccgtcaagca aaaaaaatcc tcagtgattt tcaaccagat
     6781 atcgttatcg gtactggagg atatgtttcc ggagcggtag tgtacgctgc agccaaaatg
     6841 ggtattccaa cagttatcca tgaacaaaac agtgtaccag gtgttaccaa taaattttta
     6901 agccgatatg tggatcggat cgctctttca tttaaagatg cggcttcctt ttttcctgaa
     6961 aacaaagcag ttcttgtagg taatcctcga gcacaagaag tagcagatac taaaaaatca
     7021 gatattttga aaacatttga tttggatcca gaaaagaaaa cagtcttgat ttttggcggt
     7081 agtcaaggag cacttaaaat caatcaagca gtatcagttt ttttaagtga atatattcct
     7141 tcttcttacc aagttttgta tgcttcagga gatagatatt atgaagagat cctaaataaa
     7201 ataaatcctg aaatacaaaa tattagtgtc cagccttata tcaaaaatat ggcagaggtc
     7261 atggcttcca gtgatctgct ggtggggcgt gctggtgcaa cttcgatcgc agaattcaca
     7321 gctctggggt taccggcagt gttggttccc agcccatatg ttacgaatga tcatcagact
     7381 aaaaatgcaa tgagtcttgt tcacgcagga gcagcaaaaa tgattgcaga taatgaacta
     7441 acaggtgaat cactaagtca gacagtcaac gaaatcatgg gtgatgaaga attgcaaaag
     7501 caaatgtgcc gagcttctaa agaacaagga atccctgatg cttcaaaacg tctttatgac
     7561 ttagtaaaac aaataatcaa aaaataaagg cggtggtctt agtgagtaag aaaaaagaac
     7621 caaaaaaatt gtctcatccg tcttctgatg aaaacaattt gactccttgg caaaaggcta
     7681 accgaaaata tctggcagaa caagagatga aaaaccaaga gccaaaaaaa gaagacataa
     7741 cattagatac acccctttca gattctgaag aagaaaaaac ggttcaagag gaacagcaag
     7801 aagaaagcca gtccgagaaa aaaatcgaat tttttgaaga gatcaagcaa aagaaaaacg
     7861 gtggaccata taacggttct tttttgaacc ggctgcccaa tttaaaaagt caacggcaca
     7921 aagtactatt tcgtcggtta gctttgatca tcactgtatt gggtataccg ctgatttttt
     7981 tgatctatta tgtttctcct tatagcaaat tacaagcagt tgcagtatca ggcaataaga
     8041 cagtcaacag ccaagaaatc atctctgata caaaattgtc attaggagaa aatgtttggg
     8101 gacagtattt tcatcgatct acttatatcg atcgccttaa aaaagcacag ccaagaatcg
     8161 aaacagcaaa tatacatttc aaagggatga atgaattcga tttggatgta acagaatata
     8221 aagagattgc tttgatcgca aaaaacaatc aatactaccc agtgattgaa aatggaacag
     8281 tattagatga aaaagtagca aatcctacaa aaaatctccc tatcttggaa gagttcaaag
     8341 actctgcaaa aatcaaagaa ttaacaaagc aatacaatca gttatcatca gaattacaaa
     8401 aagcaatttc tgaaatcaag tacacgccaa gagcaagcaa taaaaatctg atccaattga
     8461 atatgaatga cggcaatcaa gttattgtaa atatcaataa tcttgcgaac caaatgaaat
     8521 attattcgca agtagccaaa gatatggatg aaaaaggtgt gatcgacatg gaagttggta
     8581 tcttctcgca tccttacggt agcactcaag aaacggaaga atcgggccaa tcggaagaaa
     8641 caactgaaag tgaagaaaat gcggatcaaa caaacgaatc aagtgaagag gcagaaacgc
     8701 aaaaagcaca aacacctgga tcgtctagca caaacggatc atctgattca aatgattcaa
     8761 gtgaaacaag tcaaatagaa gataatccaa gtacaactcc gtcaagttta aatgaaaatt
     8821 gataaaacaa ctttaaaaag taagaatgta ctttctaaaa accagtaatt tatggtagaa
     8881 ttggaagcag tgaatatatc tattaataag tatattttaa aacggacgct agttgttcgc
     8941 ttgtatatgg aatagtaagt aggagggaat cccattcatg gcaaaaacag gaatgtatgt
     9001 aggccttgat attggaacga catctgttaa agttgtcgtg gctgaatata tcgacagcca
     9061 aatgaatatt attggagtag gaaacgcaaa atcagaaggg attaaccgag gcattatcgt
     9121 tgatatcgat aaaacggtcc aagcgataca acgagcagta cgacaagcag aagaaaaagc
     9181 aggtatccag atcaaaggcg taagtgtcgg tttgccagca aacatgcttg aagtagaaaa
     9241 ttgccaggga atgattgcag ttaacggaga ttcaaaggaa atcaccgatg aagatgtcag
     9301 aaatgtggct tcagctgccc ttgttcgttc aatacctcct gaacgtcaaa tcgtgtcaat
     9361 attgccacaa gattttactg tcgatgggtt cgagggaatc aaagatcctc gtggaatgat
     9421 cggcgtaaga ttagaaatgt acggtctgtt gtttacagga cctaaaacga tcatccataa
     9481 catacgtaaa tgcgtggaaa atgccggatt aatcgtcaac gaaatggtga ttactccttt
     9541 agcgctgact gaatcaattc tttctgacgg agaaaaagat tttggtacga tcgtcattga
     9601 tatgggtggc ggccaaacaa caacggctgt tatgcatgat aagcaattga agtttaccaa
     9661 tcttgaccaa gaaggtggcg aatttgtcac taaagatatc tctattgtat taaatacgtc
     9721 atttaacaat gcagaagcgt tgaaaataaa ctacggggat gcatacccag aacggacatc
     9781 accagatgaa gaatttccag tagatgtgat tggtcagtca gaaccagtga aagtcgatga
     9841 acgctacttg tcagaaatta tttcagctcg aatggaacag attttcaaca aagcaaaaga
     9901 tgcattggac caaatcgaag cattagagtt gccaggtggc gtcgtattga caggcggagc
     9961 tgctagtctt cctggtgttg tggacttggc acaagaaatc ttcggcgtaa atgtaaaatt
    10021 gtatgttcca aatcacatgg ggctgagaaa cccggtattt acaaatgtaa taagtatcgt
    10081 ggattattca gcaaacttga gtgaagtgta tcaattggca aaaattgctg ttacgggtga
    10141 aacctcagca gctcgtcaaa tggtagttga acaagaaaca acaaacacat atgagagcta
    10201 tgaagcacct gaagaaacaa tctacgatga gccggaacca aaagagtccg gagaaaatgt
    10261 aaaaaataaa atcaagggtt tctttacaaa tatttttgat taattcatcc tgggaggaat
    10321 aagatatgga attctcaatt gataataata tcaatgacgg cgcagtaatc aaagtcatcg
    10381 gagtcggtgg tggcggtgga aatgctgtaa accgaatgat tgaagaaaac gttaaaggtg
    10441 ttgaattcat tacagccaac acagacgtgc aagcattaaa aaattcaaaa gctgaaacag
    10501 ttatccaatt aggccccaaa tatactcgtg gtttaggtgc tggttctcag ccagaagttg
    10561 gacaaaaagc ggcagaagaa agtgaacaat ccttacgcga agctttagac ggtgcagata
    10621 tgattttcat cactgcagga atgggtggag gaaccggtac aggtgctgca ccaatcgttg
    10681 caggtatcgc gaaagaattg ggcgcattga ctgttggtgt cgtgacacgt ccattcactt
    10741 ttgaaggacc gaaacgtggc cgttttgctg cagaaggtat cgctcgtttg aaagaaaatg
    10801 tggatacatt attaattatc tcaaataacc gtttattaga agttgtagat aaaaagacac
    10861 cgatgcttga agctttccgt gaagcagata atgttttacg acaaggtgta caaggtatct
    10921 ctgatttgat cacagcgcca ggttacgtta accttgactt tgctgacgtg aaaacagtga
    10981 tggaaaacca aggtacagca ttgatgggga tcggtgtggc tagtggagaa gatcgcgtag
    11041 tagaagcaac gaaaaaagca atctcctctc cattgcttga aacatctatt gatggagctg
    11101 aacaagtact tcttaacatc acaggcggtt tggatatgac attgttcgaa gcacaagatg
    11161 cttcagatat cgtagcaaat gcagcaactg gcgatgtaaa tatcattcta ggtacatcta
    11221 tcaatgaaga aatgggcgat gaaatccgtg tgacggtcat cgcaacaggt atcgatgaat
    11281 caaaaaagga acgcaagtct agccgaccag ctagacaagc acaaatgcaa tcacctgctc
    11341 aaaagactgt attagatatg gatcaagcta aaccaacttc ttcagaagaa gaaaacagtt
    11401 ttggcgattg ggatatcaga cgtgaacaaa atgttcgtcc tagagttgat gattccaatt
    11461 ttgacaatat cgaaaaaaaa gaatttgata cattcaaccg cgaagaaaca aaatctcatg
    11521 gcgatgatga attaaatacg ccaccgtttt tccgtcgtaa aaaataaagg agaggaagag
    11581 cacatgattg ctgacaactt gcagaaaatc aagcaagaaa ttcaggattc gtgtgctctt
    11641 gttcatcgtg atccgaaaga agttacatta gtagctgtaa caaaatctgt tgaatccgct
    11701 caagctgaag aattggttag agctggcgtt atgaattgtg cagaaaaccg agtagataaa
    11761 ttattagaaa agaaacaaga tttatttgat tttcctgaaa taaagtggca tttaattggt
    11821 aatttacagc gcagaaaggt aaaattgatt gtaaatgaaa ttgattactt tcatgcgttg
    11881 gacagtttaa gattagcaga agaaatccag aagcggttag agaaagaatt atcctgtttt
    11941 attgaagtaa atgtttctgg tgaggaatca aaacatggaa tttcaccaga tgagctttta
    12001 ccgtttgtgg aatctttagc tgcctgcaca aaaatcaagg ttgttgggtt gatgactatg
    12061 gcgcctaaag aagcttctga tgagcaaatc cataaagtgt ttggtacgct gaaagaattg
    12121 cgtgatcttg ttcaagcaaa aggttatgcc catgcaccat gtagtgaatt aagtatgggg
    12181 atgagtcaag actttcaaat tgcgattgaa gaaggtgcaa catttatccg tgtaggaaca
    12241 gcgctattca aagacgaata aaggaggaac aaaaatgccg cttttaaaca gaggagcaat
    12301 tgctaatttt ttcggattag ctgatgagga agagtacgaa taccaagatt atcctgaaac
    12361 aacaaaaaag gctgtacagc caactaaaaa aaatacaaca cagaatcaat caactcattc
    12421 tgtatctgct gcgaatactc atgaaaaaca aaaaacggcg acttcacgtc ctgtaacgca
    12481 tgaaagtatt cagccggctg aaaagaaaaa agtaattgaa ctacatcaat cacctacaaa
    12541 aactgtagcg aaagaaagaa cagcttcaag aacctctaca caacctaaag caaatcttgc
    12601 tggaaaaatc actgtaatgg aaccaagagc ttattctgaa gctatggcga ttgctaaacg
    12661 aatcattgct ggagaagcaa ccttagtgaa ttttcattta gtagaagaaa aacaagcgag
    12721 aagaatcgtt gattttctaa caggaacagt ttatgcacta gatggagata tcaaacgtgt
    12781 tggagatgag atttttcttt gtacaccgac tgggatggag attgacagtt caaccgctca
    12841 atcttttgca gatgcgaatt tgtttgatct gtaagaggag gaactacgat ttatactatt
    12901 gcactattac ttcatttact tcaacgggca gcctatttct atagcattat cttgatggta
    12961 tatgcattgc tctcttggtt tccaggcggg tatcaatcag ggctaggacg attattagct
    13021 aagatctgcg aaccgtatat cagtttgttc gatcgtctgc ctttgaggat tggacccttg
    13081 gatttcacaa ttttaggggc aatcctgatc ttgaacttag ccgtacaagg tttagcacag
    13141 atcgttatat ggataactgt ccatttagtt tattgattga agcaacaaaa tctttattct
    13201 cagaatagat aggaggggaa aattttggat gcaaatgtat accagcactt tcgggcagat
    13261 gaacgtacat ttatcgattc ggtaggcgat tggattgaac aggttcaagg acaatatgca
    13321 ccctatctga ccgaatttct tgacccaaga caatcctata ttttagaaac actgattcga
    13381 caaagcagtg atttgcgttt catgttttat ggcggatatg aacaggcaga aagaaaaaga
    13441 tgtttgattt tccccgatta ttacgaacct gtagaggaag attttgaaac agcattgtat
    13501 gaaatccatt atcctagcaa atttgccagc ctaagtcatg ggaaaatcct tggaacttta
    13561 gtgggaacgg ggatcaaacg ctcttacttt ggcgatatca tctcggacgg tgatcgctgg
    13621 caagtattta ttgcaaatga ggtggatcat tttgttgctg cacaagtaac aaagattgga
    13681 aaggttgctg tacgcttgga accaatcaaa tacacagaaa tgattatgcc gaaagatagc
    13741 tggacacaag aaagaggaac agttagttcc atgcgactag acagtgtgat ctctgagatt
    13801 tataatattt ccagacagcg gtccaagcag ctgatcgaag ctggtaaagt aaaagtgaac
    13861 tggacagaaa atacaagacc tgattttgta cttgaactat tagatattat ttcagtcaga
    13921 ggttatggca gagtccagat ccaagaactt gaggggaaga cgaaaaaaga aaagtacagg
    13981 gtactgttcg gtgtattacg taaataaaat aaaaaggtgg tttactcatg gctttaactc
    14041 cattagatat ccaaaataag acattcccga caaaaatgcg gggatataat caagacgaag
    14101 tagatgattt cttagattta gttgttcgtg actatgagga attgactcaa agaaatcgag
    14161 aattagaaaa agcagtcaaa cattctgaag aaaaacttga gtacttcaat gaattaaaag
    14221 atgctttgaa ccaatcaatc atcgtagctc aagatacggc tgataaagta aaaacaagtg
    14281 caagcaagga atccgaagtg atcgttactt ctgcacaaaa caaagcagat gagttagttg
    14341 cgaacgctga aaaacgtgca catcaattaa caactgatgc agaagaaaaa gcaagaaaaa
    14401 tcttgacaga tgcaacagaa aaagcaagac agcttgcgac agaaactgaa gatcttaaga
    14461 aaaaaacacg agtattccat caacgtatca gcttgatgct tgagtctcaa ttagaacaag
    14521 tgaaaagtcc ggaatgggat gaaattttac aaccattctc cagctacgtg actgacagcc
    14581 atgaagtgat caaagaagtt ttagcaaaac agcttgacaa tgaaaatgat actgatgtaa
    14641 actcagacac aggagtcata gaagcaccta tgacggcatt tgatacacag gctattgata
    14701 tctcgatcgt gcctggtgaa aatgaaaacg agtagaacag aaaagcactt tgttattctt
    14761 aaagcgagcc gatgagagtg gaagttcggt aagacactgc atggtgaaag atcctctact
    14821 tgagacctgc ttttccgaaa ttagagtaag aagcagcggc tgacctcgtt attggtcaca
    14881 gagagtttgc actagataga tgcaactaaa tttgggtggt accacggcat gttcgtccct
    14941 tgcggctgaa catgcttttt tgtgtccgga aaacaaataa aggagtgtat ggttgaatga
    15001 aaatgaaaga aaccttgcaa ttaggaaaaa caaaattccc tatgcgtggt aatttgccaa
    15061 accgagaagg cgagtggcaa aaagaatggg aagaaaatcg aatctaccaa aaaagacaag
    15121 agttgaacga aggaaaacct agctttgttc ttcatgatgg acctccatat gccaatggta
    15181 atatccattt aggacattca ttgaataaaa tcagtaaaga cattatcatt cgttcaaaat
    15241 caatgtctgg ctatcgtgca ccatatgttc caggatggga tacacatgga ttgccgattg
    15301 aacaagtatt ggctaataaa ggcgtgaaac gtaaagaaat gtccatggca gaatacttgg
    15361 aaaaatgtcg tgaatatgca ctttcccaag tagataagca acgagcagat ttcaaacgcc
    15421 taggagttgc aggagattgg gaacatcctt atgttacatt agatccttct tatgaagctg
    15481 cacaagtacg cgtatttggt aaaatggctg aaaaaggcta tatttacaaa ggattgaaac
    15541 caatttactg gtctccgtca agtgagtctt ctttagcgga agctgaaatt gaatataaag
    15601 atgtaaaatc tccatctatt tttgtagctt tcaatgtcaa agacggcaaa gatattcttg
    15661 atgaagatac agcttttgtc atttggacga caacaccatg gacattgcca gcaaaccaag
    15721 gtattgctgt aaatccaaaa tttacgtatg tattggtgga agccgatggc cgtaagtttg
    15781 tcgtagcgaa agatttgcta gaaacagtcc aatcagaaat cggttgggaa aatgtaacag
    15841 ttctaaaaga atttgctgga caagaaatgg aatatatgac tgcaagtcat ccattctatg
    15901 aacgtgaatc acttgtgatt ttaggcgatc atgttacttt agacgctggt actggattag
    15961 tccatactgc tccaggacat ggggaagatg actatatcgc tggtagcaaa tataaactat
    16021 ctgtagtgtc acctgtagac tcaaaaggat tgtttacaga agaagcacct ggatttgaag
    16081 gtatctttta tgacaaagca aatcctatga tcactgatct attaaaagaa aaaggagctt
    16141 tgctgaagct agatttcttt actcatagtt atcctcacga ttggcggacg aaaaagcctg
    16201 tgatctatcg ggcaactcca caatggtttg catctatcga taaattccgt cagaatattt
    16261 tggatgaagt agaaaaagta gagtgggtta tcccatgggg taaaacacgt ttgtataata
    16321 tgatccgtga ccgcggcgat tgggtaattt cccgtcagcg tgcatgggga gtaccacttc
    16381 cgattttcta tgctgaaaat ggagaagcaa tcatcacacc agaaacaatc gaacatgtgg
    16441 caaaattatt tgctgaacat ggatcaatta tctggtttga aaaagaagcg aaagaacttc
    16501 ttcctgaagg atttacccac ccaggttctc ctaatggcga atttacaaaa gaaaaagata
    16561 tcatggatgt ctggtttgat tctggttctt ctcatgaagc tgttttacgt cagcgaccag
    16621 aattatcatt cccagcagat atgtatttag aaggatcaga ccaatatcgt ggctggttca
    16681 actcaagtat cacgactagt gtggctatca atggtgtagc accatacaaa tcagttattt
    16741 ctcaaggatt tgctttagat ggtgaaggcc gtaagatgag taaatcttta ggaaacatca
    16801 ttgcaccaga aaaagtgatc aaacaatttg gtgcagatat ccttcgctta tgggtatcta
    16861 gtgtagatta tgaagcagat gttcgtgttt ctatggatat cttaagtcaa gtggcagaag
    16921 tatatcgtaa aatcagaaat acgatgcgtt tcttattagc gaatacagaa gatttcgatc
    16981 ctaaaaaaga tactgtttcg tacaatgatt tacgttctgt agacaaatat atgaccgttc
    17041 gattgaacca agtaatcaaa gaaatccgag aagaagggta cgacaaatat aacttcatgc
    17101 atatttaccg tacagttatg aacttcttga cggttgatct atcgtcattc tacctggatt
    17161 ttgctaaaga tgtagtttat attgaagcag aagatgatta tcaacgtcgt tgcatgcaaa
    17221 ctgttttcta tcaaacagct gtagctttga caaaattatt gactcctatc attccgcata
    17281 cagcagaaga aatctggtca ttcctgaaag aagaagagga gtacgttcag ttaagcgagt
    17341 ttcctggtta tgaagagttt gcaaaccaag aagaattgat ggatacctgg actgctttca
    17401 tggacttccg tgataatgtc ttaaaagcat tggaagaagc aagaaacagc aaattgattg
    17461 gtaaatcttt ggaagcaaaa ctaactgttt atccaaaaca acaagttcgt gaaatgttaa
    17521 aagctttgga tgcagatatt gcacaattat tgatcgtttc accagactac tttgaagtta
    17581 tggcagcaga tgaacaagtg ccagataacg ctatggtatt tgatgatgtt gctattacag
    17641 tggaaaaagc agacggggaa acttgcgatc gctgtcgcca agttcgtaaa gatgtaggag
    17701 tagatgaaaa acttcctcat ctatgcggtc gttgtgcaaa aatcgttgaa gacttctatc
    17761 ctgaagctgt agctgaagga ttcgaagaaa agtaaaaggg aaaagggggt gtgacatgtt
    17821 ctttgtcaca cccccttttg ttatcaatcg tttaattttc cacgttcacg ataccagtta
    17881 tctggttgcc agatccattc gaatccgtct ttttcaagta gttcgaaagc tgctttaggt
    17941 cccattgatc cagctttgta gttgggaaaa tccggttgtg tttggtccca agcttttcga
    18001 atgacatcca cgatatgcca agattgagcg acttcttccc aatgagagaa gttcgttcca
    18061 tcaccattca acgcatctaa tagtaatttt tcgtaagctt ctgggctatt ttcaaccatt
    18121 tctgcactat ttctaaattc caatttgatt ggttccgttt caaatccttg ccctacttct
    18181 ttcccattca aggataaaga aaatccttca gttggctgaa tatagatcgt tagaacatta
    18241 ggtggaagtg tcgtatcgtc acatggttca tcgacagatg ttttgaatac attaacagga
    18301 acttgtttga atacgatgtt gatccgagtc cctttttcag tcaaacgttt gcctgtacgt
    18361 acatagaaag gaacacctga ccaacggaag ttatcgatag tgaatttgcc tgcgacgaat
    18421 gtttcagtct ctgattgagc atccactttg tcttcttcgc gatagccctt gaattgtaca
    18481 ccatccaatt caccttgagc atattgcccg cgaacgaagt tttctaacac ttcttcttcg
    18541 ttataaatgc ggatagcttt caatgctttg atcttttctg tacggatttc tttttcggaa
    18601 aatgctactg gcggttccat tgcaagtaat gctacaacct gtaaaatatg attttgcacc
    18661 atgtctttaa gtgcgccact atgatcgtag tagcccccgc gatcttctac accgaggttt
    18721 tcgccaaaag taatttggat attgtcgata tagcgattgt tccattgagc ctcaaaaata
    18781 ttattggcaa aacggatagc tgagatgttt tggatcattt cttttcctaa ataatgatca
    18841 atcctgaaaa tatcttgttc tgggaatact tctctgattt gctggttcaa ttcaaaagca
    18901 gactggtaat cagaaccgaa cggtttttct atgatcaaac gattgaagcc attttttgtc
    18961 ataatatttt gtgatttcaa atgagaaacg atcgttccaa aaaattgagg tgccatagcc
    19021 aaataataga cacggttacc gtttaattga tagtgtccat ctaatcggtc agacaattct
    19081 tttaatgtct gataatgcgt tgaatcattt acatcatggg attgatagta aaaatggctt
    19141 gcaaaggtag ttgcttcttc atctgaagga ttcaatgcac ggattgtttc tttgacaact
    19201 tcacggtagt gctcatcgct ccagggacgg cgagcggttc cgattacagc aaaatgctcg
    19261 cctaaatttc cttttctgta aaggcggaac aaagacgggt acaatttacg ctgggctagg
    19321 tcacctgtac cgccgaatat cgtaaacaat acattttttt cattagacat gtggatacac
    19381 tcctttatat tttatcgaca aaaatcgtgc tggccgcctt aaagctgacg gggattttct
    19441 ttctatcatt ttggatagtg atcggtcctt cataagctgc gatgtcaacg atctcatatt
    19501 cttcgttgat attcaggtca atagtgacta agtaatccaa caattctttt tcatcaagca
    19561 ctcgtgcgat acgcactttt gtaccgacag gataggactc caatgtttgt cggcgttctt
    19621 catggacaac ttcctctttt ttaggaatcg atcctccatg aggacaatgt tcaggatgat
    19681 tcaaatagtt ttctaaatga tctgcaagat gttccgaagt cacatgttcc aatacttcag
    19741 catcatcatg gacttcattc cagctatagt ctaaatgttc aactaaaaaa acttcccata
    19801 agcgatgttt gcgaatcaga ctgctagctt tttgcagtcc gcttgcagtc aattgtacac
    19861 cttgataagg ggaatgttct acaagctctt ctttcacaag tttagaaatc atttcactga
    19921 cagatgcagc tgagacatct agactagata cgatttgttt attgttgact ttcgttgtat
    19981 ctccacctag ttctaaaatg attttcaaat aatcttctcg atttggtgtc atattcgatc
    20041 atcctttcat ggtaaaaaac catcattagt aagtgtaaca aaaaaaacgt taattgacta
    20101 tttttctaaa taaaaaacaa aggattttta gacgttttta caacaaaaaa cgaaagatga
    20161 tagagaagac tcattctttc gtttataaag gatatatata tacattggga gggatctatt
    20221 tttcagataa caacttatat gaagtgtctg cagattcgtc ataaagagtt tgttcgggat
    20281 aagaaaagat aagataaaaa ccatactgat cacgtacgac taaacgatat tcatctattt
    20341 ctaccacaga tgtgccaaga gactgaccgt tgatcaaaaa cgtgtaatca gatgtaatct
    20401 gtaattgttg tttttgctgg ctatcactaa agaaccatgt accttgatac tttgagagtc
    20461 cttctgactt ttccgcttgt tttttctttt tcaagtaaat aaaacttgag agaacggtaa
    20521 tgagtgaacc aagaaaatag atcatttttt ttatcaccaa atcactcctt tatgagaaaa
    20581 taatcgcata gacatattct ttcttcttta tttcattgta ccgaataaaa gctaaaattt
    20641 ctctaagact ttcgactggt ttttttactg tttttctaca aattatgata ggatacatag
    20701 taggaagaaa ggtgacataa tttgaagtat cagcaagtgg aaatagcttt ttttattgac
    20761 cgcccgaatc ggtttatagc acattgtatg aaaaaagacg gagaaataat tattgcgcat
    20821 gtcaaaaata caggtagagg aaaagaggtc ctgataccag gcgctgaagt ggctattgta
    20881 tttgctcctg gacctaaacg gaaaaccgcc tatgatctga ttgctgtaaa aaagaagggt
    20941 gactggttta atatcgatag tcaattgcct aatcggctgg caattgatgg tattttagac
    21001 ggcacgatcc ttttaccagg attaactggt ccatttacgg tatacaagcg tgaagtaact
    21061 tatcttcact ccaaatttga tatttattta gagacggtgg tcggacaaaa agcatttgtt
    21121 gaagtcaaag gtatgacact tgaaaataaa gcgattggtg cttttcctga tgcgcccaca
    21181 ctcagaggat tgaaacatat aggagaatta acgtatgccg cacaagatgg ttatgccgct
    21241 tatgtcttgt ttattgctca gttcgaacat cttcatctgg caacgatcca tgaagaaatg
    21301 caaccagcac tagctgatat ggttcgacat gcgcagcaaa gcggagttca aatcctcgcc
    21361 tataattgtc aagtatcggc agatgaggta actgtcaagc aggccattcc atttgatgta
    21421 gatatccctt ttgaagatcc tatacaatag aaagaaggta aaataatgat caacttaggt
    21481 attatcggaa caaattggat tactcatcaa tttgtccaag cagctttaag cacaaaaaaa
    21541 tatgaattga cagcggtata ttctagacat ttggaaaaag cacaggaatt tggttctcat
    21601 tatgaagggg atatcgaatt cgcaacagat ttgaagactt ttttcaatat tactcatatg
    21661 gacaccattt atattgcttc tccgaatagt cttcacttta gtcaagctaa gcaagcaatt
    21721 ttggcaggaa aaaatgtgat agttgaaaag ccagcttttt cgacgccaaa agaaatggat
    21781 gaaatcatcc atttggcaaa tgaacacaat gtgtattttt ttgaagcagc aagaaatatc
    21841 catgaatcag gttttaaaaa gattgccgat tacttaccat taaaagacga gataatcggt
    21901 gcaaatttca gctatatgaa atattcttcg cgctatgacc aagtattaga tggagaagaa
    21961 ccgaatatct tctcgactca tttctcaggt ggtgcattga tggatttagg tgtttacctt
    22021 gtatatgcag ctgttgcttg gtttggaatg ccaaaagaag tccattattt cccaagaaag
    22081 atttctactg gtgtagatgg tcttggatgg gggatcttac gttatgagaa ttttgatgta
    22141 tcgatccagc caggtaaaat cggtgattct tatttaccgt cagagattta ttttgactca
    22201 ggaacgctag tgatgaatgg agtcaatgca attgaacaag cacaatttca tgatcgcgcg
    22261 cataaagaaa tcattgattt ggcggtaaca gctgcagaaa atccaatggc agatgaagca
    22321 gaggattttg ccaatgtcat ggctcatccg aaagatccag cttggggatt gttgtatgaa
    22381 gagtggatcg agctagctag aaatgtgaac caagtgattt atgatttaag aaaaaatggc
    22441 ggcatcaaat tcgatgcaga taatgaggaa gatttttaat gaacgaattt gtacaagtat
    22501 ttcccgaaaa ttggcagaaa aaatatgagg ataaagggtt tatctcacct tctcttattc
    22561 aacgagcagt ttttcagcca ctaagtaata aacaaagtat agtagcggtt tctcctacag
    22621 gttcaggtaa aacactggct tatctttggc ctctactact aaacgtggaa ccaggtgaag
    22681 caagtgcgtt ggtcattttt gcttcttctc aagaactagc tattcaagta gcagatgttg
    22741 cacgtgaatg gggaaaagac aaagagttga aagtccaatc tttggtgggc ggagccaacg
    22801 tcaaacgtca gattgagggt ttgaaggaaa aaccagaaat cttgattggt acaccaggaa
    22861 gaatattgga attgatgaaa gcaaaaaaaa taaaagcaca tcaagtgaaa acaatggtat
    22921 ttgatgaagc agaccagcta tttgacgctg ggaacagcca aatcattgat caaattcttc
    22981 atcaagctcc aacagagtat cagctagctt ttttttcagc gacagcagat cgttcccttg
    23041 aaagcattga aaaaatcact gggaaaacgt ttgagacaat tgacgtgaca gcagaggacg
    23101 attctcgaaa aggactgaga cattactttt tacgtgtacc gatacgaaag aaagatgact
    23161 acttgagacg tctcacgcat atagaagatt ttcatggtct gattttcttt aatcaactga
    23221 ctgaattagg cgtaatggaa gaaaaattgc tgtatagagg tgtaccggta ggaagtctgg
    23281 cctctgatca gaacaagcta ctccgaaaag cagcgctaga acaattcaaa aagaaaatgg
    23341 tcagagcact tttgaccaca gatgtggcgg ctagaggttt agatattaca ggtcttcctt
    23401 atgtagtgaa tgcagaagtt ccgttaagtg aagaagctta tttgcatcgt tcgggaagaa
    23461 ctggtcgaat gggtaatgaa ggaatagtaa ttacactcgt acaagataat aatctaagag
    23521 atttaaaacg gcttttacgt ccatcaaata taacacttga agagattttt ttatacggag
    23581 gtaagctgca aactgagcag ccaaccaaag aagatgcagc tcctgcagta aataaaaagt
    23641 atgcgaaaac tttttctgga aaggagcaga acccagaata taacaaagaa aaaataagaa
    23701 aaaaagttaa aaataaatca aaaaaagaga gaaataaagg agcaaggcgc aaataagcgc
    23761 ctttttatgc tatgattatg aaaacgggaa caaaattggt tgccagagga ggggttatgt
    23821 gaaagaacgt caagaagaga tcttgcagct attgacagaa aaccaacaag gattgacagc
    23881 aagtgatgta gctgagcgct taactatcga tcgaagcaat gcaagccgat atttaagtga
    23941 actatacaag gcccatcata ttgtaaaaac cgctggccga ccagtcgttt actctttgcc
    24001 aacggaaaag tcaaaatctg atgaagtgca tgtcgactct tctacgcaag tgacttttga
    24061 aacactcgtt ggagaaaatg attctttaaa agtcagcata cagcaggcaa aagctgcgat
    24121 tctttatcca ccgcgggggt tgcatacgat tatttttgga gaaactggta cagggaagtc
    24181 gatgtttgct gaatgtatgt atcattttgc aatcgattca gagatgcttt ctgcagatgc
    24241 gccatttgtt tctttcaatt gtgcggatta tgctcaaaat ccgcaactgc tctttggaca
    24301 catctttggg atcaaaaaag gggcttacac aggagcagct caagatagtc ccggtctaat
    24361 agccaaagca gacggcggta tattgttttt agatgagatc caccgtttac cgccggaagg
    24421 gcaggaaatg ctgtttactt tcattgataa aggtatttac cgtccgcttg gagaaagtgc
    24481 acaagtacat gaagcatctg ttcagatcat tggggcgacg actgaatctt cagaaagttt
    24541 cttatctacg ttcaatcgac ggattcctat ggcaatcacc ttgccgaatc ttgcttcacg
    24601 ttcactggat gagcgttatg aaatcatctc tctttttatc aaacaagaag cgaatcgttt
    24661 gaatcaacgt atcgatatcg aaaaagaagc gattcttgcc ttcatgcttt atgatgcgga
    24721 aggaaatatc ggtcaagtga aacgagactt gaaactagtc tgtgcaaaat cttttttaca
    24781 ttaccgtact catcatgaga aaaagctaat cattcgaaaa gaagaacttt cccttcaagt
    24841 acaaaaagga ttactgaaaa tcaaggaaat accggaacgt ctcgaccgat tcatggacag
    24901 caaaagtcag tatttgacat ttgaaccagg atttgctgat gttgtctggt cacaagatcc
    24961 agaacgaaac atgcaggtct ataacgatat tgaggaaaaa gtcacttctc tttccgaaac
    25021 cggtgtggag aacattgatc tagagaccct catttcaaaa gatgtggatg cttatttcca
    25081 gacatatgtc aaagaattga ctaaaagttc gattcccaaa gatcttttgc cagatgaaat
    25141 ctggcggtta accaatcaat tgtatgatgt ggctgaaaaa cggttagacc gtatttataa
    25201 tgaaaaagct cgttttgctt ttgctttgca tctgcaaagt acattggatc gtgtgagaga
    25261 aggtcatatg atcgtccacc cagatttgaa taacgtacgg aaaaatttta agagggaatt
    25321 ccaggtagca atcgatcttt caacgatcat tgaagaagaa gaacaagttg agattccttt
    25381 tgatgaaatc ggctttatta gtatgtttct ttctatcaat ctaggagaaa gtgagcctgt
    25441 taaagaaaac aaagtagatg ttctcatatt gatgcacggc agacagactg cttcaagcat
    25501 gttggagatg gcacaagaac tattaggaac aaaagtaggg aaagctttta atatgccact
    25561 ggttatggaa gttcaaacaa tgtatgaaga agtgttacaa tatgtcaaaa actatcaaga
    25621 gcatttgacg aatggcctac tcttgttaac agatatggga tcattaaaca ccttcagtga
    25681 tttgatttat gaagagactg gcattcggac gaaagctatc acgatgacaa gtaccatgat
    25741 tgtgatagaa gcgatacgga tggcaagtgt tggaagaagc ttagaagata tttatcaaaa
    25801 tatccagctt tcctttgaat cgatcgtacg tgatcagttc aaagcggaaa agtctgaaac
    25861 tttacagcgt aaaaaagccg taatcgtgac atgctttact ggtgaaggag tagctgccaa
    25921 attatatcag cgtattatgc cagtgattaa tcaaaataag gtagaactga tccagatgca
    25981 gtttttagaa cgtgaatcat tcaaaaaaca catcgatgcc ttattggaag aatatgagat
    26041 caaagcaatt gcgggaacag ttgatgttga ttatcaaaat atcccatttt tttcagccta
    26101 tgacgttttt gatgatgaaa aactaaatat tttaaagcgt atagctgatg atgagatccc
    26161 gacagctaaa attgtcgatt cacttgctgg atcattaagc gatgtctttt ctattgatga
    26221 actgatccgt tcattgcaaa agacagttca gcagatccag accgatttgt cgattatcgt
    26281 ggaacctgga gtagatactg gaatcgttat ccatttagcc ttcatgttag acggattgat
    26341 caaacaagaa agccatcggc aatttgagaa actgtctatt ttctcaaaaa tttatcgttt
    26401 ggaaatggat atcgttcggg caaacttgat ggcactagaa cgaaaatatc aggtaaaaat
    26461 tccagaagat gatatcgcat ttcttacaca aatgtttctt gaaaataaaa taaaaaaatg
    26521 aacacactaa tcatactgtt tacacactaa acatctgtgt gcgcactata aaaaagagct
    26581 aaaaagcatg aaaacgctat ttcagctctt ttttttattg gcatgcttct tgcgttatat
    26641 aaaagtgtaa aaaaataaaa ggagtgttaa aaatggcaaa aaaaacaatc atgttagttt
    26701 gttcagcagg gatgagtacg agtttattgg tcacaaaaat gcaaaaagca gcagaagaaa
    26761 aagggatgga agccgatatt tttgcggtct ctgcctcaga tgcagataat aatttagaat
    26821 ctaagaatgt cgatgtatta ttattaggtc ctcaagtacg tttcatgaaa gctcaatttg
    26881 aacaaaaact tgcgcctaaa ggtattccat tagatgtcat caatatgcaa gactatggca
    26941 tgatgaacgg agaaaaagtt cttgcacaag cagaaaatct aatgaaataa atcaagtatg
    27001 cagttggggg tataacaacg tggaagatca acaaaatcta gaagccatca tggggttaat
    27061 catgtttggc ggtaatgcaa agagcgatgc aatggaagcg attgcggctg ctaaaatcgg
    27121 tgattttgag ttagcggata ggaaaatcgc tgatgcagaa gaatcactta tacaagcgca
    27181 tcatgcacaa acagacatgt tgacacaaga agcacaagga aatcatatgc aagtgacatt
    27241 attgactgtt cacagtcaag atcacttaat gacatctatt gcgtttactg atttagcaaa
    27301 agaaatcatc gaactttatc gtcgcgtata cagcgaataa atacaacttc ttttttgaac
    27361 ggaagaagaa aaatttttga acggattttt tattttgtta taaggagaac tctctttata
    27421 taaaaaactt ataggaggaa gtaaaaaatg aacggactat caagttggat ggagaaatac
    27481 atcctgccgg ttgccgcaaa aatcggagcg caaaaacatt tagttgcttt gcgtgatgct
    27541 tttatcggca cactgcccgc aacaatggcg ggatcagtcg ctgtaatgat caatgcaatt
    27601 attcgtgatt taccgcaaca gtttaacagt acctatgctg acagtttagc agcagacaaa
    27661 ggaatctttg ccgtattgaa tgtcatcatc ggaatcaatg gttttgtctg gaacggtaca
    27721 ctagcaatcg ccggattgat ctttgccttt tcttgggggt ataatcttgc ccgagcttat
    27781 ggagtaaatg atctagctgg ggggatcgtt ggtttagcta ccttgattca aggtatttcc
    27841 tttggtccag cattatcagc agcattagat gtgaatgttc cttcaaatgt cgcagatgca
    27901 atcaatagtt ctgagattgg tgcaacgatt gcagatggca cactgtcagt tggattatgg
    27961 ggttggctaa aactagatca tttgaatgga aacgcttatt ttacagttat gatcatggga
    28021 gctatttcag tcattatttt ttgtaaattg atgcttgcca acattacgat caaaatgcct
    28081 gattcagtac caccagcagt atctaaagca tttgcagcca ttttaccagc gacgatcgct
    28141 ttatacgtca ttgctattat caattatatc gtaggtcgtg tagctgatgg gcaactgatc
    28201 attgatttgg tgcaaaaata tattgcagaa ccattcctag gattatctca agggttggga
    28261 gcagtattga tcgtcacagt atttgttcaa gtattctggt tctttggtat tcatggacca
    28321 aatgtattgg caccagtgct agagggaatc tggggacaag cacaactaat caatattgat
    28381 attttccaaa aaggttataa cggaaaaact ggtacaccag ccgtgttaga tgcaatcgaa
    28441 gatggaaaag cttatatgtg ggtccgcgga tcgttcgatg cttttgcatg gtttggcgga
    28501 tcaggcggaa cgatcgtctt actgatagct atcttgattt tctctaaacg tgcagattat
    28561 ctaacagtag ctaaattatc cattgggcct ggtatcttca atatcaacga accagtgatg
    28621 tttggtctgc caatcgtatt gaatgcaatc atgtttatcc cattcttgat tgctccagta
    28681 gtagcaacag caattggatg gacagctact tatcttggcc tagtcgctcc ggtatcgcag
    28741 caagtcacat gggtagtacc gccgttctta ttgtcattct tagcaacagg agcggattgg
    28801 cgggcaccga tcgtaacatt agtatgtatg gtcgtgactt tcttgatttg ggcaccattt
    28861 gtcatctctg caaacaaaat ggaccctgcc gcaggcgaac aacaataaga tgaacgtgag
    28921 gagcgggacg ctttaagttt cgttcctcat aatgaatttt ctaggaggaa ctgaaatgat
    28981 tacaattgcc agtgcaatgc aacaagatga aatcaaagaa ttgttagaag gatacaatga
    29041 agaaggaatg acttttacat ttaaagaaaa acaaggaatc aagctgttct ttgaaacaag
    29101 tgcagaagat ccggaagttg cggctaaaaa agcaaaggaa ctaatcaaag cacagccttg
    29161 gggaacagtc ctttattttc aatcaacagc tgtttagaaa atggtttaaa aagataggat
    29221 ggttgagatg ataaaaaacg gtttattttt atgtagtatt ggttctttga tcgtgttgta
    29281 tagtttgaat ccacattcgc aaaggtatga tttgtatagt atggtcacag gtctttttct
    29341 aacaggatta ggaatctatt tcttcatgaa ggggaaaaaa agagaagaag caaaggagaa
    29401 aaataactaa tggaaatcac gaaaaaatta aatattccag catcgttttt ttacgataaa
    29461 gttatggact ctgtcctttt cgatgtacgt aaagcgaccg gcaaatcagt aactagaaaa
    29521 cagctgaaaa atttggagta cgtcaaacaa ttctcgcaaa ataaccgggc tcgcataaaa
    29581 atcgaagaag tcattgaaaa ccagtcttat aagtttcgta catcgacaac gaagaatgaa
    29641 ttcgtcgttc attatcaaat caaaccattg gacgattcga cctgtgaggt tcattacaca
    29701 gaaaaaatgg agtcttatgg catgcttcaa aagttgaatg atatgctttt aggaacaatc
    29761 ttgatgtatt ttaaacggag acgtttcaaa aaaatgctag atatgatcga agcaacgtat
    29821 taaatcaatg aaacatggta ctatttagtt attgaaaaat gaagtaagct agaaggaatt
    29881 tttcatagga agatagatct ttcctgcgaa tcctcactag cttttttgta ggaaggggca
    29941 gcaaaatgac aaacaaagta agagagctag gtgtatcttc gattgaggaa atgtttgatt
    30001 tagccactta tgcatttaat ggggcagata cacctgaaag gcgagaacgt tttcgtacac
    30061 ttgcggagaa ttcttggaat tacggatttt ttgatgagga ggatcggcta acaagtcaag
    30121 tcatggcgac cccttttcca gtgaattttt acggacaaga gtacctaatg gccggcattg
    30181 gctatgttgc ttcttatcca gaagcaaggg gacaaggcgg gatcaatcag atcatggaaa
    30241 agatccttga agattgccgt gatcgtaaag taagcttatc ttatctggcg ccattctcct
    30301 atcccttcta tcggcgctat ggctatgaac aatcatttga taaaatcagt tatcaactaa
    30361 acagtcgtga tgtgccgttt atcaaaaaaa aatctggaaa aataaagcgt atggattttg
    30421 aagatgcaaa agctgcaatc agaagaattt atgaacagat gccggaaaac caacgagctg
    30481 gtctgaagcg cgaagactgg tggtatacgt ataaattcaa gcaaaaaggc aattaccagt
    30541 ttgctttgca ttttgatgat aatgaggaag caacgggata tatcgtttat cagcttgcaa
    30601 cgtcttcctt tattattgcg gagtggggat ttttggatca tgatgctttt tgcagccttg
    30661 ttcgcttcgt aagttctcac aatggtgctt ttgaaacatt tgaatattca tgcggctacg
    30721 gcggtaatga tcaaaattat ctattagaaa atccatttgc ttctgtaatg atcacacctt
    30781 atatgatggc gaggatcgta gatatttctt tgtttttgga aaattatcca tttaaaaaga
    30841 gacaagctgc atttgcccta caaatagaag aagatcatta tgcgaaatgg aatgaaggaa
    30901 tcgtggaagt aacaatcgaa aatggaaaaa atcatctctc aaaagtagaa caaacaaaac
    30961 tcccaatcgt tcgaggaagt atccaacata tcacgcagct attattaggg tatcgtaaag
    31021 tggaagagtt ggtattccaa gaaagaatac aggtgacaaa agaatatgaa gaaacgttaa
    31081 gctcaatctt gccacagcaa cagccaattc ttaatgacta tttttgataa aaaacgggtg
    31141 atgacaatat ttttgtcacc acccttttgt ttttcatttg gcatttgaag gaaaatgtta
    31201 aagtaaatcc tcttttttcg taaatttgaa ttttttgttt tcttttgttt tagggttttc
    31261 ttttttgtgg tcttggattg cttctttcgt aatcttttcc cgattttttt tagatgaatc
    31321 taagcgttct gcgtatactt tttcttttgg cttatcattc attggaaagg acctccctac
    31381 attatttcat tctacctcta gtttatcatc tgttaaggac tagtggaaac gttttgccta
    31441 acttataagc tgattttttt agcagataag cttgcaagta aaaaacaaac aagctacaat
    31501 tgatttattg aaattgttcc tgtagctcag taggatagag caatcgcctc ctaagcgata
    31561 ggtcgctggt tcaattccag tcaggaacgt ataaataacc cctgtatcct ttgcggtaca
    31621 ggggtttgtt ttgtatttgt gccaaaaatg tgccaaacta gttatcattt ttatataaac
    31681 tatcgaacac agtattgatt ttttctttat cctgatcttc aagctctcga acaatatgaa
    31741 gataagtaga cattgtagtt tctaaactgc tatgtcctaa acgtttcgat acgctaagta
    31801 tatttactcc ttgataaagt aaaatagatg catgtgtatg ccttagtcca tgcaaagtaa
    31861 attgcttttc aatccctaat tcttttaatt ttttgcgcaa atatttgctg acggcgtttg
    31921 atgaaactaa tccatttttt aagttgaaaa aaacaaaatt atgagggttt ttgatttcaa
    31981 aattctcgaa taattctttt tgattgattt taaacttttt taagagatca atcgtatgtt
    32041 tatcaatgga aattttccta tttgaagttt cgttttttgt ttttccccat tcatttaatt
    32101 tataattcca tgttttatta atagtgatga tttgatcttc gaaatcgata tcttcccatg
    32161 ttaatcctag aagttcagca aatcgcattc cagtggcacc agcaactaac acgagcatag
    32221 gagaagagta ctgcgcagaa aggttttctt ctacgagttt cattaaagat ttaaattgat
    32281 cataatctaa atatttatct tcttttggct tcaatgaatc ttttcctttg attactgctt
    32341 ttctagttgg atcaaacgga attaatcctt cttctacggc atctttcaac gacgctctaa
    32401 tatggttatt aaacttaata acggtagatt ttacatggtc tttagcatac ttatttaaaa
    32461 agcgttgata tcccactcta tctaaatcag aaatcaatac cgctggcata tatttcttta
    32521 tgttcattaa cgtatcttcg tattttctat aagtgatagg agatactgtt ccttctttat
    32581 aaagttgcat ccaatcctca aagtaatctg ataataatag atttttgcga tcccctttaa
    32641 ggcctttgtt caagttatat tctaattcgt tggcggcatc ttttgcttct ccttttgtct
    32701 taaatcctga ttttcttatc ttcgtgtatt ttccgtcatc ttttttgtat gaaatttcgt
    32761 attgccaact atttccacgt ttgactaatc ttgccataat tgaatcagct ctctttctct
    32821 gatacaatag gaactataaa gaagcccatt gtttgggttt tattattttt tgcacatcct
    32881 ttttgcttgc cggcgcaagg atgtgctatt tgtcgtttta atggtataat tggatgtgta
    32941 ttagatcatc caatcagagg tgtttattat gattaaagtg atttttaaaa gaataactga
    33001 acttccagag tttagattat ttgttgatta ttggtatgtc tggtttttta ttgttgcatt
    33061 gctgataggt ctagatgtca tattagaaag aaaacttaag taagagttga gttaataaat
    33121 tgaattccta aatgagatat tttgtagccc atattttgtt tgccgacatc acctaatact
    33181 atggagctaa tcgttttttc taacagacca aaatcagata atctatttaa gctaccatct
    33241 attagctctt gtgaatagcc agacatgctg atatttccag tgaaattttc gtttccacga
    33301 ctcattaagc atgctaacaa ttgaatctca atcgatgtta attgattcag tacaagaaga
    33361 taatactcct cgttatccca tgaagcgctg ttaattcgaa gtaaacaatt cttataaaga
    33421 tttttataca tatctatttt attttgtgcc tttgattttt ctacctcgtc atttatccct
    33481 tcgaatattc caatgagttg gtccttgttc tctaagttga aaacatcttc tggaatttga
    33541 tcgcgaatgt tttctaatga ttcgtttaaa tttttgtaga atttctcgat gcgtttgaaa
    33601 cgcttctcgt ttttagaccc aaaataaagt gactgcacaa cgccaccaat ataaggaatt
    33661 gctccaatac cgccttcaac tattaattca agatattctt ttttggttag tttttcattg
    33721 ctattatcca tagttacctc ctattttgtc atttccttta caagcattgt gactcctgat
    33781 ggcactcttt tgtataggtt ttattattgt gcacaatcta actcttagtg gggcgtggtt
    33841 catttatttt ttacttactt tactattaat catatcccat tgagcatagg atttttctat
    33901 gttcgatcct cttgaactaa tttctcctgt aaaagttact ttatcgccct ttgtaaaggt
    33961 atcagcattg tttaagtcct tcgcaaaaat tacatatgaa actttaggtg ttgcagaaat
    34021 atcattccaa cttttatcat cgtactcttt gtctgctata atggctattc tagtagtcat
    34081 tgattcgata acagttcctt caaaagtata tgttttacca ctaatatatt tagtaaaagc
    34141 tgtattttgc tcagtagctg gagtaataga ataataacta tctaagaaag caccccagtc
    34201 atgattattt gtctctaaaa attcttcaaa ttgagttagg cttttattgc tgctgttaga
    34261 tgtagtagtt tgagtatcag atgatgagct ttcctgtttg ttattgtcat ttgcctcgtt
    34321 tgatgaggaa agcgagaaac ctacggtagt aaaaataatc ccgataataa ggagaatcat
    34381 aggtgttttc ttatttgttt ttttgataaa tcttacaatt aacatgatta aacctataat
    34441 aaataaaaca ataccagtaa aaccaaatat accgtccatt aatagatcct ctttctcttt
    34501 tgatattgaa tattataaac caagcaattc ttttttctta aaatcgaatt cttcttgatt
    34561 aataatccct tcatctaaca actctttata ctttttaatt tcatctgcac ttgaaatttg
    34621 tgtttctttg gaattattat ctaatataga ttgttgcttc tctatatatt tttttaaatt
    34681 ttccatttca ttccaatatt tttttgtaaa cataacggtg ttttcatctt tcgtggccgc
    34741 taatatacct ccgcgacttt cgtttccgcc tagcaaggta aattgtatat aaccattact
    34801 catacctggt ttttttaatt gtacggctga tatattttta aaggggatag ttttttctcc
    34861 tttaatacct tgattaacta aatttataaa tccttttcta ataattgaaa tagaatcatc
    34921 agttacttta atcaaggttt ttcctggaga ttttattaaa atctcttttt ccattttttc
    34981 ttcctcattt ctgtgatatg attttttttg tagaagctca tatatgagga aagagcccgt
    35041 gttgcagcac gggctttttt aatgttttgc tgaaatcggt ttttttaata attcttgatg
    35101 tattcataca tattgccttg cgtaagaata ttttttctta aaatagcatt ggcagacagc
    35161 ataacaagtg tatctgagct tattctgaat agaataatac tccataaatt tttcgagatt
    35221 aaactgagat tcatcagtca gttcgttctc aatatagata tttaataaaa ttagaatagc
    35281 tattttatct gcttctgttt caaattttga gtgaaaagtt gtagaagtat cgtacaaaac
    35341 tgaaaattca aaatgagagg cgctgaaatg tgcaagttca tgagataaat gaaaggcttc
    35401 tgcagtttca ccgtatagat tttcattcaa aaaaatgatt ctgggttttg gatagtagaa
    35461 accaggctct ttcatctcca tataaactac tttcaaattg tattcgctca acatttcttt
    35521 caatttcaaa tacatacaaa ccatcactcc aactattcat tttcctctaa agctttagca
    35581 attgcaatcg ctttacgcat tgtctcctta gatatttctt ttccatcaaa agaaaaaaca
    35641 gtatcgtctt ctgataaatc cacatgttta ggggtttctc tttcttctct acctagaagg
    35701 tagtctacag agacatcgaa atagtcagca atccgactta attcatctga attaggagta
    35761 ttatttttcc actttgctag ataaccgtta gaatatccaa aattaatttc taactgccgt
    35821 atagatatct ttttcctctt cgccaagtct tttattattt cataggtatt catcgataaa
    35881 acaacctttc taaatgttta caaaaaaagt ttagaaaaat acgcagaaat aatttgacta
    35941 attctgagta atgagctata ctatatcttg taaacagatt taacaactaa aaagacaaca
    36001 aaaaacacta ttgatatgta aatgcagacc gccaagaaag ctttaaaatc aatgttttta
    36061 tgtcttattt aattatgctc ttagtataga gtattactca gatactgtca attgaattta
    36121 gaaaaaagtt gttaaatttg tttacgaata taaaagaaag gaatgagaaa tatgaacaca
    36181 ccgcaaattt ttaatttcga acaaaacgaa gttcggacaa ttttagtaaa tgatgaacca
    36241 tattttgtag gcaaagacgt tgcgagtgtt ttgggttatt caaacactaa agatgctttg
    36301 tcgcggcatg tagatttgga agataagatg gggtcgcgaa tcacgacctc aggtcaatca
    36361 agagagatga caatcatcaa cgaatctggt ttgtacagtt taatcttaaa atcaaaactt
    36421 ccctctgcca aaaaatttaa acgttgggta acaagtgaag tgttgccagc aattagaaaa
    36481 catggaggtt atctaactcc agaaaaagta gaagaagctt tgcttaatcc agatacaatc
    36541 attcaattag caactcaact aaaagaagaa agaactggaa gattaatcgc agaacaaaag
    36601 attgcagagt acgaacctaa aatctcctat ttagatagca tattatcttc tacagattca
    36661 gtaacaatta gtcagattgc agcagattat gggatgtctc cacaacagat gaataaatta
    36721 cttcataaac taggtattca gaaaaaagtc ggtaaccaat ggttattgtg caaaaaacac
    36781 atgaaccaag gatacacaaa atctcataca actgagatcc cgaaagccga tggtggcact
    36841 aaaattgtaa tgaataccaa atggacacag aaagggcgtc tatttatcta cgaattacta
    36901 aaaaaagaag gatattaccc tcaaatggat ttagaggaaa ttggttagaa aggagtttta
    36961 gtatgactga cattgcagaa atcactcaac gagatagaga aaaaatcaaa gaatatgtcg
    37021 aaagttcaaa gttcttaact tacaccatgc ttgctgaaag atttggaatt agcaaaag
//
LOCUS       DASHWW010000020        35019 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.020, whole genome shotgun sequence.
ACCESSION   DASHWW010000020 DASHWW010000000
VERSION     DASHWW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.020"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(56..2653)
                     /gene="adhE"
                     /locus_tag="U2R64_001181"
                     /gene_synonym="adhC"
     CDS             complement(56..2653)
                     /gene="adhE"
                     /locus_tag="U2R64_001181"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEM8918012.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="U2R64_001182"
     CDS             complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="U2R64_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEM8918013.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="U2R64_001183"
     CDS             complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="U2R64_001183"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEM8918014.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4798..5496
                     /locus_tag="U2R64_001184"
     CDS             4798..5496
                     /locus_tag="U2R64_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEM8918015.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5664..8303)
                     /locus_tag="U2R64_001185"
     CDS             complement(5664..8303)
                     /locus_tag="U2R64_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8918016.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8922..9953)
                     /gene="queA"
                     /locus_tag="U2R64_001186"
     CDS             complement(8922..9953)
                     /gene="queA"
                     /locus_tag="U2R64_001186"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEM8918017.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10146..11321
                     /locus_tag="U2R64_001187"
     CDS             10146..11321
                     /locus_tag="U2R64_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8918018.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11325..11966
                     /locus_tag="U2R64_001188"
     CDS             11325..11966
                     /locus_tag="U2R64_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918019.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11963..12880
                     /locus_tag="U2R64_001189"
     CDS             11963..12880
                     /locus_tag="U2R64_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8918020.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12877..13548
                     /locus_tag="U2R64_001190"
     CDS             12877..13548
                     /locus_tag="U2R64_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918021.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14089..14577)
                     /locus_tag="U2R64_001191"
     CDS             complement(14089..14577)
                     /locus_tag="U2R64_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HEM8918022.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14778..15044)
                     /locus_tag="U2R64_001192"
     CDS             complement(14778..15044)
                     /locus_tag="U2R64_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEM8918023.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15044..15307)
                     /locus_tag="U2R64_001193"
     CDS             complement(15044..15307)
                     /locus_tag="U2R64_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEM8918024.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            15783..15968
                     /locus_tag="U2R64_001194"
     CDS             15783..15968
                     /locus_tag="U2R64_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8918025.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16110..17933)
                     /locus_tag="U2R64_001195"
     CDS             complement(16110..17933)
                     /locus_tag="U2R64_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEM8918026.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18531..21236)
                     /locus_tag="U2R64_001196"
     CDS             complement(18531..21236)
                     /locus_tag="U2R64_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEM8918027.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21542..22489)
                     /locus_tag="U2R64_001197"
     CDS             complement(21542..22489)
                     /locus_tag="U2R64_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HEM8918028.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22679..22948
                     /gene="rpsN"
                     /locus_tag="U2R64_001198"
     CDS             22679..22948
                     /gene="rpsN"
                     /locus_tag="U2R64_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEM8918029.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23124..23486)
                     /locus_tag="U2R64_001199"
     CDS             complement(23124..23486)
                     /locus_tag="U2R64_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8918030.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23497..24618)
                     /locus_tag="U2R64_001200"
     CDS             complement(23497..24618)
                     /locus_tag="U2R64_001200"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEM8918031.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24634..24984)
                     /locus_tag="U2R64_001201"
     CDS             complement(24634..24984)
                     /locus_tag="U2R64_001201"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEM8918032.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25114..26625)
                     /locus_tag="U2R64_001202"
     CDS             complement(25114..26625)
                     /locus_tag="U2R64_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEM8918033.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26947..28299)
                     /locus_tag="U2R64_001203"
     CDS             complement(26947..28299)
                     /locus_tag="U2R64_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEM8918034.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28452..29528)
                     /locus_tag="U2R64_001204"
     CDS             complement(28452..29528)
                     /locus_tag="U2R64_001204"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEM8918035.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29724..31469
                     /locus_tag="U2R64_001205"
     CDS             29724..31469
                     /locus_tag="U2R64_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HEM8918036.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31749..32186)
                     /locus_tag="U2R64_001206"
     CDS             complement(31749..32186)
                     /locus_tag="U2R64_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HEM8918037.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32170..33543)
                     /locus_tag="U2R64_001207"
     CDS             complement(32170..33543)
                     /locus_tag="U2R64_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918038.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33865..34353)
                     /locus_tag="U2R64_001208"
     CDS             complement(33865..34353)
                     /locus_tag="U2R64_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918039.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34375..34977)
                     /locus_tag="U2R64_001209"
     CDS             complement(34375..34977)
                     /locus_tag="U2R64_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEM8918040.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7477 c         6465 g        11158 t
ORIGIN      
        1 ttttccaagt tctttttcat ctattttctt atcttttttc tacgctttct tttgcttatc
       61 cgttgtaagc atcaatgatg atctgtttca attcagagat caatggttct ttcggattag
      121 ctgtcgtaca ttggtcttcg taagctaatt cagccatacg gtctacggtt gtatctagtg
      181 tttcttgtgt gactccttga gcttttagac tcatgttgat gccgacagat tttcctaatt
      241 cataaacagc cgttgctaaa gcttcgacta attcctctgt tgtttcgcct ttcagaccta
      301 agaattttgc gatatctgcg taatctgtat ctgcacggaa atagtcatat ttagggaaca
      361 tcgcatgttt ttgtggatct tttgcattat agcggataat atgcggtaaa agaatcgcat
      421 ttgtccgtcc atgagggatc ccgtattccc cgccgatttt atgtgcgact gagtgacaaa
      481 tacctaggaa tgcgttagca aacgccatac cagccattgt agaagcgttg tgcatttttt
      541 cacgtgattc catatcaggt gtttttactg atttttctaa atagtcaaag actaacttga
      601 ttgcttgtag gctcaatcca cgtgtataat ctgaagccat gactgaaaca taggattcga
      661 ttgcatgtgt taacacatcc atcccggtat ctgctgtgac agatgctgga actgacatga
      721 cgaattgagg atcgacgatt gcgacatctg gcgtcaatgc ataatctgct aacggatatt
      781 tcacatgtgt ttcactgtca gtgatgaccg caaatggcgt tacttcagaa ccagtccctg
      841 atgttgtcgg gatacatacg aattgtgttt tttctggttt gtcgatctta tatgtccgtt
      901 tacggatatc caagaatttt tgttttgcac caaagaaaga tgtgtctggg tgttcataga
      961 acatccacat tcccttagct gcgtccattg cagaaccgcc tccaagagcg attactgtat
     1021 ctggcttgaa gtctgccatc agtttcgttc ctgcgtatac ggtatttgtc gatgggttcg
     1081 gttcaacatc tgagaagact tcgatcttca catcattttt acgtcgtgcc aatacttcac
     1141 gaactgtatc gcagtaaccg aattggacca taccagggtc acaaacgatc atgacacgtt
     1201 caacgttttc cattttctct aagtacaata gagagttctt ttcaaagaag atttttggcg
     1261 gtaatttgaa ccattgcatg ttatttctcc gtttcgctac agttttgaca ttgattaagt
     1321 ttacagcaga gacgttacga gaaacagagt tcttaccata agaaccgcat cccaaagtca
     1381 atgacggaat catttcgtta tagatatcac cgatgccgcc ttctgcagat ggtgtattca
     1441 ctaaaatacg acaagctttc attcgaagac cgaatttgac atgcaactct tcgttttctg
     1501 aatggataac tgctgtatgt cctaatcctc caagattcaa cataccttca cacaaatcaa
     1561 acgcatggtc cgtgttgtta gctttgatca tggcaagaac tggagaaagt ttttctcttg
     1621 atagcggata atctggccct acgccttcca attcagcaat cagcattttc gttccttttg
     1681 gtacactgat tcctgccaat tttgcgattt ccatcgcaga atgtccaacg attgatggat
     1741 tgaccgcata ttttccttcg ttcatcactg catcttctaa tttttgcaat tcatctggtt
     1801 ttacgatata aacttggtgt gcttggaatt ctgcttttac tgctgcatag atttctttat
     1861 ccacgatcac agcttgttca gaagcacaaa tcattccatt atcaaatgtt ttcgaaacga
     1921 tcaaatcgtt cactgcacgt ttaatttttg ctgttttttc aatataagct ggtacgttac
     1981 ctggacctac acctaaagct ggttttcctg tagagtaagc agacttgacc attccagctc
     2041 cacctgtcgc taagacgatc gcgatacctg gatggttcat tagcatagaa gtcgcttcga
     2101 tcgaaggatg ttcgatccat tggatacaat tttcaggagc tccggcagcg atagcagcat
     2161 cacgtaccac tcgtgctgct tctgcagaag atttttgggc acttggatgg aaagcaaaaa
     2221 cgattggatt tcttgttttc aacgcgatca ttgatttgaa aatcgttgtg gaagtcggat
     2281 tcgttgttgg agttactccg caaaccacac cgactggttc agcaatttca atcaaccctt
     2341 tttggacatc ttcattgatc acaccaactg ttttatcatg tttgatatta tgccaaatat
     2401 attcggacgc atacatattt ttgattgctt tatcttcgta aacaccgcgg cctgtttcct
     2461 ctacagccat cttcgctaat ggcatatgtt gatccaaagc tgccattgcc atttcatgca
     2521 cgatatggtc tactttttct tgatcaaagc tttccatttc tttcaatgct gcatttgctt
     2581 tttctgccaa atcatcaatc attgcttgta cgtcaattgt cttcgttttt tctttttcta
     2641 ttactttagc catcattatc ctcctaatgg gtcatggtta tttgttaaat aattcacatg
     2701 tatatcatac aatatttatt tttctatgta aacacttttt tgtgattttt ttcacagtta
     2761 tttttaaata taaaattgct ttatttacag gtgtttgtat agaaaaatat ataaagttat
     2821 ttattattat ttatatgaca cacccgatta ttcaatattg agcaatatat cccatgctct
     2881 tatctctttc ttttttgaat aaaaaatgag gtaggacatc tttctgccct acctcgtctt
     2941 taaataagct ttgatactta tttttcttcc ttctcttctg tctcttccag cgtttctgtt
     3001 gtttcagttt ttacttcaac tgtctcagct ggttcttctg ttgtttcaac agtagtcgtt
     3061 gcatcatttg ttacgacagt ccctggtttg accgttttga ttgctgcacg atcgtactca
     3121 aggaagatcc cttcgcagtc taaaacaact gtccgtttgt cattgtcgat ttctgaaaca
     3181 actccatgta atccgccgat cgttacgact gaatcacctg gtttcatgct atctaacaag
     3241 ttttgacgtt cttgctgttg tttcttttgc gaacgtgaca taaaaaacca cattgctaat
     3301 agcgcgataa acatcacaag cattggtaat gttcccattt ttttcacctc actaattctg
     3361 tatctacaaa aaacacttta gcagaaaaat gctgataaca ctagtttttt acttaatttt
     3421 taaaagattt tcctttagaa gctttttgcg ttttctttat tgaacccgta ttcttcaaaa
     3481 aaggcttctc taaattcaag caaattatca tccatgattg cttgacgtac ttgtttcatt
     3541 agattcaaca agaagtataa attgtggtaa gaagtcaaac gaatcccaaa tgtttcatca
     3601 catttgatca aatggcggat ataggcacgt gtatagtttt tacatgtata acaatcacat
     3661 ttctcatcaa ttggacggaa atcatgggca tatttcgcat ttttcactac tagacggcct
     3721 tgagaagtca tacatgtgcc atttcgagcg attcgagtag gcaagacaca gtcaaacatg
     3781 tctactccac ggataacacc atcgatcaat gaatcagcag caccgacacc catcaagtaa
     3841 cgtggtttgt tttcggggat caacggtgta gtgaattcta atacacgatt catttctgat
     3901 ttaggttccc cgacagataa cccgccgatt gagtaaccag ggaaatccat cccgactaga
     3961 tctttcgcgc tttgacgacg aagatcttca aaccctgctc cttggatgat tccaaataat
     4021 ccttgacggt ctggattagc atgagctttc aatcctcgtt ctgcccatcg agacgtacgt
     4081 tctactgatt ttttcacgta gtcgtaactt tcatcgaatg gtggacattc gtcaaaactc
     4141 atcatgatat cagagcccaa tttattttgg atgttgattg ctttttctgg tgataaaaac
     4201 atacgcgaac cgttcaagtg atttttgaaa tgcacgcctt cttcttcgat attccgcata
     4261 tcacttaatg aaaaaacttg aaagccgcct gaatctgtta aaatcggttg atcccagttc
     4321 ataaatttat gcagtccgcc agcttcttct actaagtctt caccagggcg tagccataaa
     4381 tgatatgtat tacttaaaat aacgccagca cccatttctt tcaactcttc tggggacatt
     4441 gtttttactg tagctaatgt tcctactggc atgaacattg gtgtggggaa agttccgtgt
     4501 ggcgtgatca attcccctaa acgcgcgcca gtatgttttt ctttcttgat taaacgatag
     4561 cgaatggcag gttgcgtcat tcatttccct actttctata taaaatatct tgacaactcc
     4621 caccatcata atcgtttcaa gtgctttttg caagttccct cggcttcctt ctactttatt
     4681 taatattctt ttttttatcc tttttttatg aataacaaaa aaaagaaaaa cattatgaca
     4741 gaaatatttt ttgatacatg gtatattggt gttattaaag aaaaggaggg aaaaatcatg
     4801 caatcttctg cagaattaaa acgccaagca aaagagagtc taaaaggacg ttggggacaa
     4861 gctgttttac taaatctaat ccctacattg attggtattg ctactattct tcttattatg
     4921 attcctatta tcttgtttgc caccaccata tatgatggat cagcgagcgt ctcagaagcg
     4981 acaacttcag gaggcggtag ttcaggaggc ggtggcggaa ttatttccag catcattagc
     5041 gctttgttca tgagcggtat ttcttggact tatcttgata ttttacgtgg acaaaaagat
     5101 cagatcgaac cattcaaaga tgcatttcgt ggattcaaag gtttgtttat cggcggagtg
     5161 atcagcttag ctgtgctgat ctcgatcttt acaacattat ggggtttgct attagttatt
     5221 cctggaatca ttaaaagcta ttcttattct caaagctatt ttatttacta cgatatcgtc
     5281 caagaaacag gacaaacacc taaagtactg gatacgatca ctgcaagtcg aaaattgatg
     5341 gatggttata aaggacaact tttctggtta gatctttcat ttatcggctg gcatatctta
     5401 gcattagcaa ctgctggtat tggttatcta tggctcagcc catacatttc tgcaacaaaa
     5461 gcagcatttt atgaacaatt gccaaaagat atttaaaaga gagtgtgact tgtgaccgag
     5521 ggggtggcag gagaacaccg tttatcgaga ggcagtaaaa gaaacattca gcccattagc
     5581 aaaaaggagg tgtgacaaca ttcatgtcac acctcctttt tgtatagttc cagtaaaaag
     5641 aaaatcaact tagaaacagt taatcattcc tcttcttctg cttccggtaa tcgatggaac
     5701 ttgatcagtt cattcaccgc gattggtacg atagataaaa tccctaccaa gaaccagtga
     5761 ttcaaactga tgtgtactag gccgaatagt tcttgcgtaa atggcagcaa agcaacagcc
     5821 gttgtaatag ctaatgccag taacgccatt tctaccaaag ctttattggt cgctaaattg
     5881 actttgaaga tcgattggct gctgcgtaca ttgaacacat gcagaatcga tgaataagct
     5941 aagatcaaga atgcaacagt ttgaccgaca tgctgacttg cgtctaccca tgggctgata
     6001 gtatcgacat aactacctaa ataataacca aacaaggtta cgatggtgaa gacccctgca
     6061 tttatggcaa ttttttgcaa taaacctcga gcaaagatcc cttcattttt cggaatgggt
     6121 ggctgatcca tgatgccgtg ttccgctggc tctcttccta aagcaaatcc tggaagtcca
     6181 tcagcaacta cattgacaaa cagtagttgc acagctgtaa atggtgctcc ccatcctaac
     6241 agcatcgcaa tcaaaacaat aaagatctcc gaaatattac agcttagcaa aaagttgata
     6301 gctttacgaa tattctgata aaccgaacgt ccttgactga cagcgtctac gatcgtcgca
     6361 aagttgtcat ccgtcaaaat catatctgcg gcactttgcg ccacatctgt tcctgtgatc
     6421 cccatggcac acccaacgtt acttgctttc aacgctggtg catcattcac accatcccca
     6481 gtcatcgcta cgactgcacc cgtacgttgc caagatttga cgatccggat cttgtcttct
     6541 ggcgttaccc gagcatagac agagagagct ttgacacgcg catctaattc ttcgtctgat
     6601 aattgatgca gttctgatcc tgaaagtgct tctgacggat cattcaagat acctaattct
     6661 ttcgctatgg cactggcagt caccacatga tctccagtga tcatgactgt tttgatgcca
     6721 gcctttttcg ctcgcttgat tgctccttta ctttctggac gtggtggatc gatcattccg
     6781 atcagaccaa tcaaacgtaa gtctttttcc agtgcttcag aagaaatatc ttgcggttct
     6841 tcgtcataag tagcataacc aacagcaatc actctcagtg cccgtttacc aaagcgatca
     6901 ttaacgatcg ccgcttgttc tacatcgcct gaactaaagc gcggagcaag aacatcgaat
     6961 gctcctttgg tgattgagat gtatttttcg cccatttggt gaactgttgt catcattttt
     7021 cgttcagaat caaaaggaag ctcgtttact cgtggatatt tttcttctaa ttctgccttt
     7081 gtatgataat tctcttcaac agcccttacg atggctactt ctgttggatt acctttgata
     7141 acaaggtcgt catcttcttg ctcgaccgtc acatctgtac atagtgcagc cattttcaat
     7201 atttccatcg cgctgttcgt cattgaatct tcgatattcg ttacttcatc ttctttgctc
     7261 catacccggc ggacgcgcat ttcattttgt gtcagcgttc ctgttttgtc tgagcagata
     7321 acattagcgg ttcctagcgt ttcaactgct ggcaactgtc ggatgatcgc atgtttcctc
     7381 gccatcttct gcacaccgta tgcaagtgtc aacgtaacaa taacagtcaa ggtttccggt
     7441 acagctgcaa cagccaagga aatcgaagtc atgaacatct caaggagtgg ttctccttgc
     7501 agttcaccaa tcacaaatac taaagccgca gccgctaaag cgatcatact gattcgtttg
     7561 cctagctgat tcaatcggac ctgtaaaggt gttttttgca tagtattttc gttcaaaaga
     7621 tccgcgatct tacccatttc tgtagccatg ccaatggcag tgacgatcgc tttcccacga
     7681 cctgcagcaa ccgtacatcc tttaaatacc atattaagtt ggtcacctaa tgactcatct
     7741 tcttcagcaa taaatgctgc atctttttca actgcttcac tttctccagt caacgccgat
     7801 tcttctacac gtaattgtga tgcttcgatc aaacgggcat cggcagaaat agcatcaccg
     7861 gactctaaaa caagaatatc acccactacc agttgctctg actcaacagt ggtcactttg
     7921 ccgtctcgta tgacagttgc cgtttgttta ttcatatctt gcaaggattc cagtgctttt
     7981 tctgcgtttc cttcttggac aatcgccaat accgagttga tcacaacgat agcgatgatc
     8041 agcagtcctt caaataaatc cccatgttct gtagcaaatg cggtataaaa ggaaatcacc
     8101 gctgctacaa gaaggatgat cgttgtaaaa tcggacaagc ttcgaaagaa ttttttgatc
     8161 atcgattctt tcggcgcctc atcgaattta ttcaatccct gcttttttcg ccgttcatcc
     8221 acttcttgtg aagacaaccc agtatctgga tctgcttctg ttaccttctt tacttcttct
     8281 attgtctgct tgtattcttc catcctattc ctcctttaaa atcttcgtac aaaaaaaggt
     8341 acttatttta ctataacatc ctttttttat ttacttcaaa taaagggctt atcgattatt
     8401 tgttaagaaa gcgtaaaatt taaagtgctt atatttgcaa acgctaccaa aggatgctat
     8461 tatatagatg taaggaagga ggataccatc aaatagacag aagaatttct cgatagaaca
     8521 gtgtaagcaa acaaagttgt tagaagtaca ggtttcaccc agacatgcgt gtagagtaca
     8581 aacctataaa tagtgaatgc gtatggatgt ttggatcacg aagtatccga aacaagaagt
     8641 aatgcgatac gtaacaattg aataacgtaa acgtctgaaa attgaatagg aacaagagat
     8701 gtttcaaatg ttgaagatgt aacgaaaaca aaatttttgt ttaacatgaa gaaattcaac
     8761 accgtgcttt gcatgtatga tggaaagtta caatcatttc tgtttatttg aatccttccg
     8821 aggtacaaga aagccgagct tatcgagagc tcggcttttt ctttgtcata aaatctttgt
     8881 aaagcttttt tgttattcaa aactagcggc ttttcataac cttatttcac gaacatcgca
     8941 tctccaaaac taaagaaacg atagcgctct tcaatcgcat gctggtaagc agataaagtc
     9001 aattctcttc ctgcaaaggc actaactaac atgactaaag tcgattttgg caaatggaaa
     9061 ttagttgaga aagcttctac cactttgaat tcatagccag gcgtaatgaa aatatcagtc
     9121 catccgctgt ctgctttgat ttctccatta aatttcgttc caatcgtttc taatgttcga
     9181 attgaagttg ttccgacagc cacgattttc ccgccatttt tacgtacttg gttcaatcgc
     9241 tcagccgctt cttccgtcaa acggtagaat tcactatgca tatggtgttc ttcaatttta
     9301 tctacgctga caggtcggaa tgtacctaac cctacatgta gtgtcagata gactaattca
     9361 acaccctttg cttcgatctc atcaagtaat tctttcgtaa aatgcaatcc agctgttggc
     9421 gctgcagcag aaccattttc tttcgcatag acagtttgat agcgatctgg gtcttccaga
     9481 cgttctttga tatatggagg caatggcatt tctcccaatg attcaagaat ctctagaaaa
     9541 attccttcat actcaaagtc aatgatccgt ccgccgtgtt ccaattcttc tttcactact
     9601 gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa ctttggcacg tttcgcaggt
     9661 ttgatcaatg tctcccacgt atctccttgt gtattcgtta gaagaaggac ttctaaatgc
     9721 gcaccagtat ctggtttttc tccatataaa cgagcaggca gaactcgtgt attattcata
     9781 actagcgcat caccaggctg taactcttca atgatttcat ggaaatgttt atcttccatc
     9841 tctccagttt tccgatccaa aacaagtaaa cgagaatgat cgcggtcttt taatggtgtt
     9901 tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt ctgttgttaa catatcgtca
     9961 ctcactttct atcatgtgct tcatcattct atcatgtttt tcgttctgtt ggcaaaatca
    10021 gcactttttc acttctattt tttgttttcc taaataaaaa aactacccta tttgtatttt
    10081 ttcattgttt taggcatact agtaatagat agttcttcat tgaaaataga aaaagaggtg
    10141 gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa aggtggaaaa gtcgctgtag
    10201 aggacgtcaa tctttcattt gaaaagggtg agttcatttg ttttatcggt acgagcggaa
    10261 gcggaaaaac gacgacgatg cggatgatca accgaatgac tgatccaaca caagggaaaa
    10321 ttttgattga tggaaaatcc atccaagaaa ttgatccagt ggaattgcga cgtcagatcg
    10381 gctatgttat ccaaagtatt ggattgatgc ctcacatgac gatccgtgaa aatatcactc
    10441 ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa taaaacagct gaaaaaatga
    10501 ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta cccacatgaa ttatctggtg
    10561 gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc gaatcaagat atcatcttga
    10621 tggacgagcc attcggtgcg cttgatccaa tcactcgtga ttccttgcaa gaccttgtca
    10681 aagatttaca agagcgtttg ggaaaaacga tcgtatttgt aacccatgac atggatgaag
    10741 cgattaaact agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata
    10801 caccagaaaa tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag
    10861 atcgcctact acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag
    10921 caatcacgat tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac
    10981 gtgtagatac gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag
    11041 aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg
    11101 ttttttacgt aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg
    11161 ggctgaaata cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg
    11221 catcattagt ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg
    11281 ttgcagagtc agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc
    11341 atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg
    11401 ctttgatcat tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa
    11461 aagctgccac gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt
    11521 tattggcatt gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct
    11581 ttatttattc attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt
    11641 ggaattatcg ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg
    11701 ttgaattgcc cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg
    11761 tgattgcatg ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt
    11821 ttagtggact gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa
    11881 ttttagcact attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg
    11941 cacttagaga ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc
    12001 tcttcttata cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac
    12061 catttcgatc acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg
    12121 aatggttgaa cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac
    12181 tatcaaccat caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg
    12241 aacagattta acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc
    12301 taccgtgaaa gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt
    12361 tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa
    12421 agtcagcgat ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat
    12481 caatcgtaaa ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc
    12541 gatattacct atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat
    12601 tgttcttggc tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga
    12661 tgatcgtcaa ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc
    12721 tgatacgcct catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa
    12781 aatgcaggaa ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca
    12841 acgtttctta caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat
    12901 gtctttcaac aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt
    12961 atccgtcact tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg
    13021 gttgggatca tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat
    13081 atcatccaga cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg
    13141 ggagtcaatg tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat
    13201 acgtataccg ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg
    13261 atgactgcta gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg
    13321 gcaggcataa gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc
    13381 ggtgctggtg gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg
    13441 attattttag caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta
    13501 ggtattttgg aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa
    13561 aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt
    13621 aaggcaataa tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct
    13681 atttatccat tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc
    13741 gactaagttt ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc
    13801 atggaattca taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc
    13861 aattcttaca tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt
    13921 cgatgccttc agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct
    13981 tttatacaat cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca
    14041 gcttctcgcc atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca
    14101 tccgtcgcaa ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac
    14161 caattgatcg atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg
    14221 tgatgcattg ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc
    14281 cgtttgagtg acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac
    14341 gacactggta ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc
    14401 tgggaaccaa taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc
    14461 tgtttctcga taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt
    14521 cgttgccact gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact
    14581 tcttcctcct tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc
    14641 cttcaaaggt ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt
    14701 ggttttagaa caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa
    14761 ggttggctct tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta
    14821 ttttcctcat caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg
    14881 ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc
    14941 aatgtctgaa tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa
    15001 tccactttcg cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat
    15061 caatatcatc gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta
    15121 aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa
    15181 tcaatacagc attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat
    15241 ttacctcttt caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat
    15301 tagccattgt ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca
    15361 aaaaaataca ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa
    15421 agaccccttt ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg
    15481 gtagccaaac gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa
    15541 gcctgtgagt ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga
    15601 ttgatatctt gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg
    15661 attttggccg tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat
    15721 tcatgttcac tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa
    15781 aaatggcact gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt
    15841 atgaagacac atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct
    15901 gtacattatt tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt
    15961 acagctaaat aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata
    16021 gagggcacct ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag
    16081 agggtctgtt tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg
    16141 acaacgatat tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg
    16201 agaatattct gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag
    16261 ttttgtttcg ctgcattttt acttacgata tctacataac ggataattgg attttcaatc
    16321 gagcgataag aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct
    16381 gcttcgattt ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca
    16441 taatcaccga tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg
    16501 actaatacaa gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga
    16561 agctgttctg ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt
    16621 ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg
    16681 attgcatatg agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt
    16741 ccttcttttt tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg
    16801 ccgatagagt ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg
    16861 atcgaaccta gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct
    16921 tgatacatgt gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca
    16981 gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa
    17041 tacaaaatac catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt
    17101 tcaggaacga tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag
    17161 atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat
    17221 ggtacagcat tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct
    17281 cgtaaaatca aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc
    17341 aatggcacag cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca
    17401 aggataaatg tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga
    17461 ttcagcatca tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt
    17521 gctggcaccg ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac
    17581 atgtagtcga tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca
    17641 ctgctgacga catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat
    17701 agcgttaatg aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg
    17761 gctgcagcag acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat
    17821 gataacgcat cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca
    17881 ttttcagcag attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa
    17941 actcctttac acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat
    18001 gttatagtac gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa
    18061 acagaaaaat atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt
    18121 tatgggcttt ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt
    18181 tctatccttt ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc
    18241 attcttacta ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa
    18301 gcttgcatct gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg
    18361 gtcgttctta ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca
    18421 atcagctgac cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca
    18481 tttttttctc taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa
    18541 atatggctct catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag
    18601 attgccgttc ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc
    18661 gtagcatttg gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta
    18721 aatggcaaga acggattgat catttggaag aatttccctg agacttggat cggatagttc
    18781 ccgcctccgc cagagatcga cagtactaag atgataatag cgatcccttt accgacatta
    18841 tcgaataatg cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca
    18901 aatgacacgc tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat
    18961 gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat
    19021 tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca
    19081 acacttgaaa gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta
    19141 gctgaaccgt tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta
    19201 aagaagtcac tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg
    19261 acttcttgtt cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt
    19321 ggccagtcat tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt
    19381 ttttcattta ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt
    19441 tggataaaat cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat
    19501 aggtctgccc cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta
    19561 ttggcatcat ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt
    19621 gccactgcat tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg
    19681 tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga
    19741 gaagtgacag tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta
    19801 ttaacaacgg catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga
    19861 acagctgtgt tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga
    19921 tttagctgat caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc
    19981 aggaactcga ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg
    20041 ttcaatacat tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct
    20101 gttcttacag tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat
    20161 gtaacatcta cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat
    20221 tttgtttggt ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata
    20281 tcttgtactt gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt
    20341 gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg
    20401 atctctggga ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc
    20461 attttgtcat tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc
    20521 acgaattcat ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg
    20581 aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata
    20641 tctttaactt tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat
    20701 actttcaata aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc
    20761 gaacttgctc ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta
    20821 tattcgattt ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa
    20881 tcctttggca agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt
    20941 tcttttgaat caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact
    21001 tgctccccaa tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca
    21061 gcaattggca gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac
    21121 gcatatagcg aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg
    21181 aaaatccgtt tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt
    21241 ctcccccttc ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat
    21301 cggctttttt caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc
    21361 tcttacatat tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg
    21421 aaagataatt ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca
    21481 ttttttgtct ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt
    21541 cttatttttc gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat
    21601 gtgcttggat gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg
    21661 ctcctttttg gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc
    21721 ttggaacaaa cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt
    21781 catttaatgc aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga
    21841 tacttccttt cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat
    21901 ttgttttatc ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt
    21961 tactggatgc actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg
    22021 acccgaccgc acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca
    22081 aatggttgat tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc
    22141 aactcatttt atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt
    22201 aagtcccgcc gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg
    22261 aaccaatctc tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg
    22321 ttcgtatctc tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg
    22381 cttttatttc tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt
    22441 caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct
    22501 ccctttttct ttaagtttac gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt
    22561 ttggcgcatg attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta
    22621 tctaaaagcg taaagattac gatttacgct aataaaaaat aattggagga atttgttgat
    22681 ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc
    22741 tgctttacgc caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt
    22801 agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata
    22861 catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat
    22921 tccaggagta aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg
    22981 cgcatggacc actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc
    23041 tggtactaga agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag
    23101 gctgcatggt tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca
    23161 ctaattttca atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt
    23221 tctttcaatc ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt
    23281 tctattcctg ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt
    23341 tttgccgtta tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga
    23401 ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca
    23461 aaataaatat ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat
    23521 ccgctgtcct aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc
    23581 ctgcatagtg atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg
    23641 aaattcttga ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca
    23701 gtagttccct tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata
    23761 accgatcggt atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc
    23821 gattccttca cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc
    23881 tggctgcaat ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc
    23941 tactccataa cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt
    24001 gctgacatgt acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc
    24061 tttttgcaga ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa
    24121 accttcccat tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc
    24181 aggtgtacaa aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg
    24241 cgtctctagc ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc
    24301 tgcagttact gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt
    24361 caagataagg atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt
    24421 tgaaacacaa aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc
    24481 atgaccgtat ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc
    24541 aacttcattt gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg
    24601 gtgccaagcg acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa
    24661 agctgtttca tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt
    24721 cacaacaggc tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc
    24781 gatcccagtt ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa
    24841 ttctacttgg cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat
    24901 tcgtgcaatg aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc
    24961 atcgatccca attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc
    25021 attctaccaa attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt
    25081 ttctcttaaa aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa
    25141 tccgcgtttt ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct
    25201 ataaccgcct tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt
    25261 tccgccacca cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc
    25321 tggtgtgatc ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag
    25381 tgcaactaaa tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt
    25441 atctagacca ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc
    25501 tttgaatgct tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt
    25561 ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc
    25621 ttttccggca cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat
    25681 atcatagttg tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt
    25741 cgctacaagg atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg
    25801 ttgagacaaa tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc
    25861 caattcgtct acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac
    25921 atcaaacaag cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg
    25981 atcgatcaag tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat
    26041 gaatttaacg ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg
    26101 tctttgatca ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa
    26161 catttcatct gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg
    26221 gttaatgtgg tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa
    26281 gccacggatc tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt
    26341 gtcgcgccct aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc
    26401 gataactaaa ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc
    26461 aaatgcagct gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa
    26521 tgctagtgga atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac
    26581 tgatttcaac aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata
    26641 tggttgttaa ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt
    26701 attgtttctt tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc
    26761 accgaaaaat cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct
    26821 ttatcattat tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt
    26881 tctcttcatc tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac
    26941 agatttttat ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct
    27001 gccttttagc ataatactat ctgttgctgc aagattttgt ttgatagcat caatcaattt
    27061 attcttttct ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc
    27121 ttttagtgca tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat
    27181 atgttcactc atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc
    27241 taacacagcg attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc
    27301 catggctgtt ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt
    27361 tagccattcg gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg
    27421 tatggacagt ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata
    27481 acttccaggc agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt
    27541 tccttttgct gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt
    27601 ttgtactaat gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa
    27661 tccgtctgat acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga
    27721 cccaagattt tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc
    27781 cataagtgaa agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt
    27841 ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt
    27901 tccttgcgtc ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt
    27961 ggtggtttta ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta
    28021 ataggttgcc aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt
    28081 ttttggagct tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc
    28141 ttgctggata aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc
    28201 ggttatcttc cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct
    28261 gcccacggct tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg
    28321 ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat
    28381 ttctctattc gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc
    28441 tttatttctc tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt
    28501 cctaactgga tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag
    28561 agtgggtaca tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat
    28621 tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg
    28681 taagctaact tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga
    28741 atctgcattt cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct
    28801 tttacgactt caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg
    28861 atttcgcgcg cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt
    28921 gctaaagcat tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc
    28981 atattcgccg gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact
    29041 tttttaggat tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca
    29101 ccagcagctt gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat
    29161 acgcctgcgc cgacataagg catattcaat gtctctaaga agccttggat cgttccatct
    29221 tccccgtttg gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc
    29281 ggattgatca cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga
    29341 tgcaagacat ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct
    29401 tcttttgtaa taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact
    29461 gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta
    29521 atcttcaaaa gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta
    29581 gcacaaaaca aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga
    29641 acgagcgtca tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat
    29701 gataaagaaa aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa
    29761 tcattcgagt gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg
    29821 aacaggtaaa aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc
    29881 tttctgttcg agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag
    29941 atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc
    30001 tttcattatc agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg
    30061 ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc
    30121 ctaacatcgc cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga
    30181 tcaaatacat tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac
    30241 gttccttgat caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc
    30301 aaaagaacaa tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga
    30361 aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg
    30421 aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg
    30481 caaagctttt agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg
    30541 atcctcatcc agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta
    30601 gccgaaaaac tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca
    30661 cttctgcaga agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg
    30721 ggcatctttc tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga
    30781 aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg
    30841 atgaaagtcg gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta
    30901 ttgatgaaat caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata
    30961 atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg
    31021 tgatccgcgt cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac
    31081 attattttct cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat
    31141 tggaagggat gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt
    31201 ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca
    31261 ggatcgaaag tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag
    31321 ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag
    31381 ggatatttac gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga
    31441 tccaaatgta taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca
    31501 agaaataaga aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat
    31561 ttttcgaaga ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca
    31621 cccagtaata agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc
    31681 cctttttgat gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt
    31741 ggtaaacctt agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc
    31801 gtaaagggtt ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa
    31861 cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac
    31921 actcgcacac ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag
    31981 tcattcttct taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg
    32041 tagacgattt ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg
    32101 ataaccacgt caagaccata ggattctcct aattttatga catcttcttt tactggagaa
    32161 ccatctccat caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt
    32221 tactaatccg ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac
    32281 actttctatc ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc
    32341 catttctttt gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc
    32401 tttattttga gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt
    32461 ttgataatat tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa
    32521 gacacctatc gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag
    32581 caattgcata gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt
    32641 tgctgcaatc aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc
    32701 gtacagtatg ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt
    32761 tagaaaagta aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa
    32821 aacaaacacg aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct
    32881 ttcatcgaat aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa
    32941 taaaacaagc tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta
    33001 acgcggataa tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa
    33061 gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca
    33121 gatagctgca aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg
    33181 aaaattgacc gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact
    33241 tgaaaaataa aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc
    33301 accaatcagc agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt
    33361 gactaaaaat agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag
    33421 ccaattatgc gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt
    33481 acttaagata aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa
    33541 catgacaatg gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa
    33601 ggggaaataa accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat
    33661 aagcttcttt ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca
    33721 aaagtcttgc ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg
    33781 tgcctccaaa atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa
    33841 tttactttaa cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat
    33901 ttgaaatcct tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt
    33961 ataaacctcg attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt
    34021 tgtttgcgca gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg
    34081 tactttattt agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc
    34141 agtgtaaccg acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag
    34201 ttctttttga atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg
    34261 accaatgatc ggcacaaaag cttccggcca tacttcttgt atgactgcca tcagctcatc
    34321 cagttcattt tctgttactt ttattttttc catacaccca cgtccttttt tacattataa
    34381 atgaccttgc gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca
    34441 tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc
    34501 tactagacag atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt
    34561 tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga
    34621 taaaataagc tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc
    34681 cccaatcact aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat
    34741 gcccgctact gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa
    34801 cagaacaaat atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt
    34861 gctcgatcga aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag
    34921 accaataatg ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta
    34981 tattccccac atcttttttc atttattaaa actgcctcc
//
LOCUS       DASHWW010000021        33841 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.021, whole genome shotgun sequence.
ACCESSION   DASHWW010000021 DASHWW010000000
VERSION     DASHWW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.021"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            89..829
                     /locus_tag="U2R64_001210"
     CDS             89..829
                     /locus_tag="U2R64_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8918041.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1253..1423)
                     /locus_tag="U2R64_001211"
     CDS             complement(1253..1423)
                     /locus_tag="U2R64_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8918042.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1617..1796)
                     /locus_tag="U2R64_001212"
     CDS             complement(1617..1796)
                     /locus_tag="U2R64_001212"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918043.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1806..2030)
                     /locus_tag="U2R64_001213"
     CDS             complement(1806..2030)
                     /locus_tag="U2R64_001213"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918044.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            2183..3295
                     /locus_tag="U2R64_001214"
     CDS             2183..3295
                     /locus_tag="U2R64_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8918045.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3373..3666)
                     /locus_tag="U2R64_001215"
     CDS             complement(3373..3666)
                     /locus_tag="U2R64_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEM8918046.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3834..4148
                     /locus_tag="U2R64_001216"
     CDS             3834..4148
                     /locus_tag="U2R64_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEM8918047.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4169..6148
                     /locus_tag="U2R64_001217"
     CDS             4169..6148
                     /locus_tag="U2R64_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8918048.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6161..6487
                     /locus_tag="U2R64_001218"
     CDS             6161..6487
                     /locus_tag="U2R64_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEM8918049.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6503..7021
                     /locus_tag="U2R64_001219"
     CDS             6503..7021
                     /locus_tag="U2R64_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918050.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7021..8373
                     /gene="celB"
                     /locus_tag="U2R64_001220"
     CDS             7021..8373
                     /gene="celB"
                     /locus_tag="U2R64_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEM8918051.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8457..9962)
                     /locus_tag="U2R64_001221"
     CDS             complement(8457..9962)
                     /locus_tag="U2R64_001221"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEM8918052.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10054..10644)
                     /locus_tag="U2R64_001222"
     CDS             complement(10054..10644)
                     /locus_tag="U2R64_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8918053.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10823..12469
                     /locus_tag="U2R64_001223"
     CDS             10823..12469
                     /locus_tag="U2R64_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8918054.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12518..13237
                     /locus_tag="U2R64_001224"
     CDS             12518..13237
                     /locus_tag="U2R64_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEM8918055.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13716..14663
                     /locus_tag="U2R64_001225"
     CDS             13716..14663
                     /locus_tag="U2R64_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918056.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14675..15595
                     /locus_tag="U2R64_001226"
     CDS             14675..15595
                     /locus_tag="U2R64_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8918057.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15636..17093
                     /locus_tag="U2R64_001227"
     CDS             15636..17093
                     /locus_tag="U2R64_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8918058.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17438..18052
                     /locus_tag="U2R64_001228"
     CDS             17438..18052
                     /locus_tag="U2R64_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEM8918059.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18045..19769
                     /locus_tag="U2R64_001229"
     CDS             18045..19769
                     /locus_tag="U2R64_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8918060.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQLRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19766..21217
                     /locus_tag="U2R64_001230"
     CDS             19766..21217
                     /locus_tag="U2R64_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8918061.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21690..23843)
                     /locus_tag="U2R64_001231"
     CDS             complement(21690..23843)
                     /locus_tag="U2R64_001231"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEM8918062.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23845..24891)
                     /locus_tag="U2R64_001232"
     CDS             complement(23845..24891)
                     /locus_tag="U2R64_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8918063.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25041..26330
                     /locus_tag="U2R64_001233"
     CDS             25041..26330
                     /locus_tag="U2R64_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEM8918064.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26343..29045
                     /locus_tag="U2R64_001234"
     CDS             26343..29045
                     /locus_tag="U2R64_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEM8918065.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29030..29887
                     /locus_tag="U2R64_001235"
     CDS             29030..29887
                     /locus_tag="U2R64_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8918066.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29958..30857)
                     /locus_tag="U2R64_001236"
     CDS             complement(29958..30857)
                     /locus_tag="U2R64_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEM8918067.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            31026..33197
                     /locus_tag="U2R64_001237"
     CDS             31026..33197
                     /locus_tag="U2R64_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEM8918068.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33265..33606
                     /locus_tag="U2R64_001238"
     CDS             33265..33606
                     /locus_tag="U2R64_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEM8918069.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
BASE COUNT        11013 a         5907 c         6950 g         9971 t
ORIGIN      
        1 ggtagaaact caagcgccaa cggggtatga attagatgcg acaccgatcg agtttgagat
       61 cgaaagaagt cagacagcgg tggtagaatt gacgaaagca aaccgactta caccaggcgg
      121 tgtcgtgttg acaaagatcg atgaccaaag cggggaagtc ctgcaaggag ctgtttttga
      181 gttacaagat gccaatggaa ccgttctgca gtcaggtcta accacaggag cagatggaaa
      241 actggcgatt gacggcttag caccaggagt gtatcagctg gtagaaaccc aagcgccaac
      301 ggggtatgaa ttggatgcga caccaatcga gtttgagatc gaaagaagtc agacagcggt
      361 ggtagaattg acgaaagaaa atcgacttac accaggcggt gtcgtgttga caaagatcga
      421 tgaccaaagc ggagaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      481 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgatag atggcttagc
      541 accaggagca tatcagctgg tagaaactca agcgccaacg gggtatgaat tggatgcgac
      601 accagtaact ttcaagatcg aaaaagaaca agaagtggcg atctttttaa caaaagagaa
      661 tagaaaagtt gctgatagct cagatataag aggaaacaat ccaacaagca gtggaaataa
      721 gcatcttcca aaaactggag aaaccatcat tagccagttt atattgtcaa tattgggtgt
      781 gctacttgtt ttcatcagta taaaatttag aaagaaacga aatatatgag ctaaaataaa
      841 aaattgaata agcatagttt ttaaaatcaa ctagtaccca tcaattgaat ggaaactacc
      901 gattttagaa ggggtataca aacaaatatt agtatcggag tagagaaggt tgaacccaac
      961 cagtaaataa gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa acctttgtag
     1021 taatactagt taataaaaaa tatacaaaaa cactgcgaaa atcattcttg agtttcgcag
     1081 tgttttttgc ctaatgactc aagtttattg ggtaatactt tgattttctt tctacaaata
     1141 atcagcgatc agttgtaatt ttttctctag ttttaatggc tctttgtcaa taaggagaaa
     1201 aacaagtcgg gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa ggttacgcct
     1261 ccttgaaagg cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca tttggtagaa
     1321 catgtttggt gagctgaaag taggtggcgt tcatgtctgt aactaagaat tctatttctt
     1381 taggattagt gcagctaagg aaatagtttg ttaatcgagg aattttttgt gtaggtaaat
     1441 tttctcgatt aatttttctg tctcgccatc cgcggaaata aaactcagtt tatcctcaac
     1501 ggaaacgtga gaacgaaatt cacaaccctc aacactcaag acagaattct tttggaagac
     1561 tttggtaaat agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa agatacctaa
     1621 caacttttcg aaataaaaaa taacgacact ttttcagtca gtaaagaagt gattttatgt
     1681 ctgacatgat ttgaaatcga gtgccttgga cggataaaat aactttgagc gttccaatgg
     1741 cttcgacagt ttttacaggt atagcgctgc ttttttaggc gtataaccat tggcatatga
     1801 ttatattatt caaagtggac aatggtttcc ttcttcttgt ttttcaccac cattaatttc
     1861 ctatttccat ctaccacagc agaaccacaa tttctacaga cacatggagc agggaagaga
     1921 actgcagcaa cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac ctctgtaatc
     1981 atcaaatttt tgtctattga tctcagaatt tttttgatag aaccattcat aaagcatatc
     2041 gttctctcag ttgtttattt tgtggtgatt taatcataca agaaaacgat atgttttttt
     2101 ataaaaacat gaataggaaa aatagttgac aagaaaatga caacgccata tgatgttcca
     2161 tagtatttac aacctgtcat agatgactgt aaaaaataaa agtaaaaaga aaggacgaca
     2221 acaggtggat ttttatcagt ctctacaact agatccgttt attttaaaac aaaaaatacg
     2281 agaagcagct tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt tacgatcatt
     2341 attcatcgta ttgtttgcca tttgttttat cattataatt acaacattat ttgaatcgaa
     2401 gcataaacca tacgctgtgg ttttattctg tatgttgatg agtattcgtt ttgttgactt
     2461 tggttataag atttcccatt cgatcatagg tttagcaatc gtcatgttct cactattagt
     2521 agcaccgtat gtccagctga tcaaatggtc agttatgggc atgttgattc attttatttt
     2581 actaagcagc atattaatgg caaccgctag tgatcccaaa atggggaatg cttctttgta
     2641 cggcttttca tatctcttta ttgtttattc gttacctaaa gattcgttga acaagaattt
     2701 ctttacacaa acaagtagct tattattttt gtttttttgt tggttttcag ttctccttta
     2761 cagaaaacat cgagaaaaga acaaagacaa aagcttgttt aaagagattt ttttgaaagg
     2821 catgtattcg caggaaaaaa tttggatgct catctatgca tttggcatta gtcttttgat
     2881 cgttgcagga gagtatgtcc cttttcagcg attgatgtgg gcagggtttg cattttcttc
     2941 tattgtatct agctatggat tgatgtcgat tggtttcaaa gaacgagcag tagaccgaat
     3001 cattggctca ttgattggat gtgttttatt tattggtatc agccaattta ttccttttaa
     3061 ctgggtcggt atattaggtg gtctagcttt aggtgtttgt tctacctata gatataaaac
     3121 agtttttaat tcttttggtg ctttggcaat cactgccagt ttattcgggg ttccaggagc
     3181 agtaacgatc cgcatttttg agaatatcct tggggtatgt ttaggaatca tgtatattgg
     3241 ggtgactgaa atacttatcc gaaaaataag agaaaaacac ggtttgaatc attagatgag
     3301 atcgaataaa aaataaggaa aaagtgaaga tacacatgga tgataaattg ctatcattcc
     3361 atgtgtatct ttttacggta aatcagtgaa acgttcgact ttcattttta atttatactt
     3421 tttacggagt tcgtttattt gagccatcat ttcggatttg tgatgctttt cgattgcttc
     3481 ttcatctttc caacggtcga tcagtaaaag agattctgga tcttctagtg gaaagtaata
     3541 gtcatatttc tcgtttcctt cttctgcacg aatcgctttg acaatgtttc tttcgaccat
     3601 ttcttctgca aattttctgg cttgtccatt tgtacttgta tacaaaatat tcactgtgat
     3661 actcactaaa tcccctcctg aaaaaattct atcactagta tatcacggtg ccagaaatta
     3721 ttattcaaga tatgatacac attttttccg caatgctacg gaaatatata ttttgaatag
     3781 aaaacgctta caagatatgc ttggtttata aaaataaaag gagtgattga tttatgaaaa
     3841 aagcattgat tatttgtgcg gcaggaatgt catcctcgat gatggcctca aagacaacgg
     3901 atttctttaa gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct acagaaggcg
     3961 ataatatgat taagaatagt gattttgatt tatttctgat cagcccgcaa acgacgatgt
     4021 ttttggataa attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt agtatccctt
     4081 tccaagcgta tgtcccaatc cctacaggca tccagaagtt agcagaggtg atcgaagaga
     4141 acatatgatg gaataggagt ggatgataat gaaacagaag gaaaaattgc tgttgagata
     4201 tttgattgat cacaagaagg agtatgtcac cagtcaacgt ttagcttctg aattgttatt
     4261 atctgatcgg acaatccgta attacttgca gcggatcaaa gagttagtag aaaaaaacgg
     4321 aggtaagatc attgctaaac caggttatgg ctaccaactg catattttac aaagactgac
     4381 atttgacttg tttttgagtc ggcaagaaat agtacctgga tatgctagag aaccgcaagg
     4441 attttatgag tccgaagatc gacaaaagta tatattgaac caattgcttt tggaagatgc
     4501 cattcttttt atggatgatt tggcagaaga gctttatatc agtcgttcca gtttgacaaa
     4561 ggacatgcaa gaaatcaagg agcgattgat tccatattca ctaaaaatcg tttctaagca
     4621 tggtcaaggg acatggatcg aaggggaaga aagaaatcga cggcatttta tcatggatac
     4681 tttttttgga aaccattatg gaaattcatt gaaagaatat ttagggcaaa gccgtttttt
     4741 cccagacatc agttttgaag agctagtcat tatcattctc gatgaaacaa gagaagctaa
     4801 gttaaaagtt tcggatttta tcatacagaa tctgacttta cacttggctt tggggatcaa
     4861 acggctccga gaagggtttg aaatcaagga attaggcatc gaacaagaag tttctaagcg
     4921 agtagagtat caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg caggtgtatc
     4981 gtttcccgaa gaagaaattg cttatttgac attacatctc atggctaagt cgaatcacaa
     5041 agaaaatcaa aatgatcagg aactatcaaa ggaattagcg aaagttctga aaagattgtc
     5101 tcaggaattt catttttcat tagtagagga tctccagctt ttcaatggac tactcgatca
     5161 tttgtcaccg atgatgattc gattgagccg aggtattcgc attgagaacc cattgactga
     5221 ggagataaag aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt tcagcaacat
     5281 gccggctttg aaaaactata ccatcaatga agatgaatgg gcctatttgg ctttgcatct
     5341 catggcggca ttggaaaaag aaagagctgc gcataaacta catgcattga ttatctgtgc
     5401 aacgggttac ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat tcggtaaaaa
     5461 tattacagtg gtaagtgtaa aaggctatta tgagatcaat gaaacaactt taaaaggaat
     5521 cgacctgatt atttcttcta ttgatctttc gacaatgttt ttcaaaattc cagttttaca
     5581 tgtcagtatt tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag ttggagaatc
     5641 tataccctat cattcctcag atagaccgat accagcattt tctctacagc aaaaaaagca
     5701 gatttacacc gaacagttgt ctgaaaaatt tttcaagact tatacgtacg aaccgaaaaa
     5761 ggaagaaatt cttcatgatt tgctgcaaaa gctgagcata aatgaagaag aaggatatat
     5821 aagagaaatg cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca tattcagtga
     5881 tacagtggca gtcccacatc ccgctgttcc agttggaatc gaaacaaagg tagccgttgc
     5941 attgattcct tctgggatgc agtgggatca atatcaagaa attcattttg tttttttagt
     6001 ttcgccttct tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa tcgttaggtt
     6061 agttgaccag ctaaaagtac agcaggaaat cttagctgaa cctatttttg agaatttcag
     6121 cagtaaattt atcaaactga tcgaataagg aggaaaacag atggctgaaa aaataaacag
     6181 tgaaacacta caagtgactt cttttgatat cattttccat agcggaaatg cacggacact
     6241 gatacatgaa gcatttcgct cgatgcgtaa agagatgttt gaagaagtag aagagaagtt
     6301 gcgacaagca aatgaagaga ttcttcatgc gcatcagtca caaactcaac ttctgaaaga
     6361 atatgccagc gggacaaaaa tagaaatgga aattatcatg gtccatgcac aagatcatct
     6421 gatgacgacg atgacattat tggaagttgc acaggaaatg aattatttgt atcaaaaaaa
     6481 taaatagaaa ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg aattagaaaa
     6541 aaagcaactt agtttgaaaa acatgtattt caatcgttat ctaatcgtac gttacctgac
     6601 tgcctttttc tttttcatga acatgcaatg gatgattctg cttctatcag ctaaaagttt
     6661 aggaagtagt ttaccgatga ttctgatttt agctattttg cctgcagtag gagaacaagt
     6721 aaagctttat cgaaaacacc aaacgaacgt tccatggaca aagtggtatt ttttgttcca
     6781 gagtgtcttt aatttattag tgattccagt gttgtttacc tcaggattta cattcttgta
     6841 tccttttatg gcaaataaca atggaggaca gttatttgtt ttcattcttg ttgtaagcgg
     6901 tatttttgcc agtgcattta tacagtatcg tttaaagaaa atttcactca accaagacca
     6961 acagtatatc cgtattaaac aatatgaaaa agcgttatat ttaggaaagg agaataacta
     7021 atgtttgatt ttttgcagaa atacctgatg ggacctatgg ggaaaattgc gcaacttaaa
     7081 atcgttcggg ctgtcatggc agcggggatg gcttctattc ctttcacgat tgtaggctcg
     7141 atgtttttgg ttttaaatat tttgccatta ccgttcccat ttttagaagg attttttaat
     7201 gcaacttttt tcaaagttag tgacttgtac atgatcgtca atacaatgac gatggggatt
     7261 ttatctattt actttgccat tgtgtttgct tatgaattaa cgtcaattga acgagatgaa
     7321 caaaaattaa atgttaatcc gctcacgggg gcattactat ctgtttttgc attctttatg
     7381 tgtatccctg aattgatcat gactgatggt aaaatcagct tgattgcttc tatcaatgag
     7441 acagaaactg tagtaaatgg tattaggatg ggctcttttg tcgaacgttt aggaacttca
     7501 ggaatcttta cagctattat tatgtcgatt attgcggtcg aattgtattg tatgtgtgtc
     7561 aagagaaatt gggtcataaa aatgccagat gttgttccgc caggagtttc tcgttctttc
     7621 actgctctga tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa tggattatta
     7681 gttgcactag gaacggatat cttcaaaatg attgctatcc catttgggtt tgttacgcag
     7741 ttgacgaata catggcttgg tgtcatggtg atttatttct tgatccatgc attgtggatc
     7801 gtagggatcc atggagcgaa tatcatcact tctttcttga ccccgatcgt attagctaat
     7861 atggcagcta acgcacaagg cgcaaattat ccgttggcag gagaattcaa caattcttat
     7921 gtaaccgttg gtggatcagg tgcgacttta ggattgatca tctttattgc attcctcgcg
     7981 aaatctgatc agctgaaagt gttaggaaaa gcctcacttg taccaggatt attcaatatc
     8041 aatgaaccaa tcattttcgg gatgccaatc gtctacaatc cctatttagc ggttccgttt
     8101 ttcttagctc cgatggcttc tgctacactc gcttattttg ccattcggct ggaaatcgtc
     8161 aaaccgatgc ttgcacagat gccgtggcct tcaccagtcg ggatcggagc atttgttggt
     8221 agtggtggtg attggaaagc tgctgtgtta gcagtcattt gtgcaatcat cgcattcatt
     8281 atctggttcc catttatcaa attctatgat aataaattat taaatgaaga aagagaaaag
     8341 gcagcagaat tagctagtga aaagttaaaa tgatttctaa gaaaaaagga actgtgacaa
     8401 aaaatcacag tccctttttt tcttagaaat gggaaaccac tagtatataa ataccattat
     8461 tcttcaatca accgcttcac gattgcataa tccccttcat aaggttcatc tacaccattg
     8521 attttttgat agggatccac gccttttccc gcaataacga ctgaatcttg cggagcgctt
     8581 tctgctaaag cgcgtcgaat cgcttcagga cgatccattt cataatgaac gatcaaatct
     8641 ggattagtaa ttgcttcatt gatttcttcc gcgatttttt tcggatcttc aaatgctggg
     8701 tcatctgccg tcaaaaaggc gatgtcagct gtttctgata gcacttttcc aaaatcatgt
     8761 cgacgggaga ttgctttgtt tcctgggctg cctaatacaa caattacacg gccatctgga
     8821 tgttcatttt tggcaaattt cagcaatgtt ttcaagctta gataattatg tgcatagtcc
     8881 acatagacat gcgctccatt ggattggatc aattgatcca ttcggcctgg tacacgagct
     8941 tcttttaatc cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc ggcaatgatc
     9001 gcactggctg cattttcttg gttgaatcct ccagccagca aaatatcata agcagtatcg
     9061 cagatagcta agcgatcttc atgagaagat aaagtaaaac cgtgagtacc tttatctgaa
     9121 cggatcactt gataattgct ttcttccgaa cgaccataag tgatcgttgg aatctggaat
     9181 agatcggctg tttccctaag taaatcaaaa tagtcacttt catgatttaa aacaactgtt
     9241 tttgaattca agatcaattg tcgcttgcaa tagaaatagt catcaaatgt cggatgttcg
     9301 atcggactga tatggtcagg cgagatattc aagaagattc cgacatctaa agtcaagccg
     9361 tatacgcgtt gtgttttgta agcttgtgaa gaaacttcca tcactagatg agtcatacca
     9421 ttttcaactg cttctgacat catacgatat aaatctaatg actcaggcgt tgtcaaatgg
     9481 gatttgaaat atgttttgcc atctaacgtt gtattcatag tagaaagcaa tgctgttttt
     9541 ttatttgttg tgtgatccaa gattgctttt gtaaagtacg cagcagttgt tttacctttt
     9601 gttccagtga atccgatcac tttcaattta ttttgcggat agtcgtaaaa agccatagca
     9661 agaagcgcca ttgctttacg gatatccgtt acgatgattc ctactgctga attttcgtat
     9721 ggttgttctg atacataata ttgaataccc tgttcgattg ctgaatccaa atattcttct
     9781 ttgaaattca ttcctttaca gaaaaacaaa gtagaagcat cagcttttct tgaatcataa
     9841 cttaactgaa gaaattcagc tttttctggt acatcaagat gccagcctct tgttgaaaca
     9901 aattctttta atagattttc ttttaatagt aaatgacgga tgtcttctaa agagaagctc
     9961 attgattgat ccctcgcttt attcaatttc ttggtttatt atagcacact ctttttaata
    10021 tatcgtttgt ttccgctatg acaaaatcca gctttattca aattttcttg acacagggga
    10081 caagcggatg agtattttca taaacaatga actgactgta atagatagga gaacgaatag
    10141 tgtctccaac aatccaaaaa cataataatt caaaaagacg ataagactat tggtaagtaa
    10201 aagtccttgc ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg gtatcgttat
    10261 accgccattt gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga acaaaagact
    10321 tcctgaaatc agtgaaaaga aatgtgagga gatcatttcc acttttggaa caatctctaa
    10381 aacaacagga aaaagcagac ttcccgctac agtcttaaaa aatactgatt ttcctaatag
    10441 gacagcggct agaagcagca tcataagatt gatgctccaa acagtaactg agcgttggat
    10501 agaaaaggcc gtttcaacta aatgtccgat ggcgcccact ccggcggaag ctatatcgtg
    10561 agggagcaag aaccaattca atccaactgt gataaagaaa agacctaaaa atataacggg
    10621 tagttttttt atttcttgtg tcattgatat ctcctataaa tgttagccat aaaaggctgt
    10681 atatttcttt actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt gttcttataa
    10741 aagttatata aaatcgattg ccagtttctg ttttaccaat taaaatgata gtaatgtttt
    10801 gtagaaagtt ggaatctgac cgatggataa tcaaagaaaa ccagcattag atcaattaac
    10861 accgcaagaa aaaatggcac gaggctctgc ttggatgacc gccagtaata tcatttcaag
    10921 attgctaggc gctgtctata tcattccctg gtatgcttgg atgggcgaaa atgctaaggc
    10981 tgccaatgga ttattcaata tgggatacaa tatatatgca ttgtttctac tgatctctac
    11041 agcaggaata cctgctgcga ttgcaaaaca aactgcacgc tataattcat tgaatgaata
    11101 tggcacttca cgacgattat ttatccgtgc attacagatg atgggcgggt taggcctgtt
    11161 gtttgctttg ttcatgtaca tcgcctctcc ttggctagct catgcttctg gtggcggaga
    11221 agaactgatt ccaacgatgc gttctttgag tatcgctgta ttggtttttc cttgtatgag
    11281 tgtgatacga gggtatttgc aaggcaatca agaaatgatg ccttatgcgc tgtcgcagat
    11341 tgtagaacag gtggcacgta ttttttatat gctattggct acattcatca tcatgaaagt
    11401 catggatggt gactatgtga cggcggtcac gcaatcaact ttcgcggcat ttatcggtat
    11461 gctagcaagt attcttgtcc ttttgtattt tttgaagaaa catcaagcgt atacatcggc
    11521 gtttattcac tacagcgaaa acaaaataaa tattgcaacg aaggaattgt tgttagatac
    11581 cgttaaagaa gcgattccgt ttattattgt gggttcaggg gtaacgatct tcaaattagt
    11641 cgatcagttc acttttatga agatcatgtc tgcatccacc gagtattcca atgcacagtt
    11701 actggatctt ttttcgattt ttagtgccaa tccagataag ttgacgatgg tagttattgc
    11761 attggcaaca tcgatcgcgt ctactgggtt accgttgatt acagaagctg ttacgttgaa
    11821 agatcgagta ggtctggcaa aattgacaag cggaaattta cagttgtttt cattttttat
    11881 gtttccggcg acatttggtg ttatgttact tgcctatccg ctaaatacat tattttatac
    11941 accggattct ctaggaagta atgtactgat ccaagcaagt tttgtaggac tcttcctagg
    12001 actatatatg ctagtttcca acatgctgca aggaatgttt gaaaacaagg cggcaattaa
    12061 ttatttggtt attgggtttc tagtgaaact ccttcttcaa tacccagcca ttcgtttatt
    12121 tgaagtatac ggccctttat tggcgacaat gatcggattt gctgtgtctt gtaccttgat
    12181 cttaaagaga atccatgaag tagcccgctt taaaccaagt tttgtctggc gcaggacatt
    12241 gctgatcttt attcttacct tgattatgct tttggcttcg tggatcacaa agatgatttt
    12301 tggtgctttt ttaaacgaag atagcaaatt ccagtctcta ttgttgattc ttgtagtagc
    12361 aggtataggg gctttagtgt atggttattt agctttgaaa atccgcttgg cagaaagact
    12421 actaggacca ggaatagcgc gtttacgaca taaattaaaa ataaaataag tgaatcagaa
    12481 gagctagatt gatgctcttt tgaaatgggg gaaacgcatg cgtttagata agtttttagc
    12541 agatatggga cttggcagcc gcaaagaagt caaaggatta atcaaaaaag gaacgatcga
    12601 agtcaatgga caagtggtga aaagcgataa agcgcaagta aatgaattcg aagatgcggt
    12661 tacttattta ggagaaatca ttacgtatca aaaagatttt tactacattt tgcataaacc
    12721 tgcaggagtc atttctgcta ctcaggataa tcatgatcaa accgtaatcg atttattgga
    12781 agaccaggat tatcgggaag atctttttcc agtcggccga ttagataaag acacagaggg
    12841 cctcttgatt ttaacgaatg acggggtgtt tgcccatcag ttactatcac ctaaaaaaca
    12901 tgtggagaaa gaatatctag ctgaggttag cggtataatg acagaagaag atatccgttt
    12961 atttgcagaa ggactgatta ttgatggcga tgagcagaca ttgccggcaa aactccaaat
    13021 tgatcaagta gatcaagaga cagaaacttc aattatccgt ctgattttgc atgaaggaaa
    13081 gtttcaccaa gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat atttaaaaag
    13141 aatccgtatg ggaaaatttt ggctgcctaa agatttgaat aaagggcaat atcgacccat
    13201 gaccaaagaa gagctagaac aagtgagaga aaaataattg aatggatagc taaaagaata
    13261 agcagagtag ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt tcggatggct
    13321 tttttgtgaa atttcggctt atttccgtag aagctacttc tggaacaccg tttgttcgga
    13381 ataagggact gtgacaagac ttttgttaca gtccccattg ttccttgtga ctcagagtta
    13441 gatagtaagg acacgatctc cctaatactc aggccaaaac gctgaattca caacctctga
    13501 taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa aatatgagga
    13561 actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca caacctctcc
    13621 tatactttgt ttcattttcc ctatactttg tttatttatt ctcattattg aaagcgctat
    13681 aattacgttg cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag gggttcaatc
    13741 atttttttat gaatctatgg cgttataaag cacttgtcct gatggctgta ccgggtatgc
    13801 tttggatgat ttttttcttt tacatacctg taatggcgaa tgtcgtagca ttcaaaaatt
    13861 ttcatatttc agcagatggg ttcttggcta gcttgaggga aagtccttgg gtgggttggg
    13921 aaaatttcaa atttttattt tcttcggatc aagcatttct catcactaaa aatacaattt
    13981 tatataatgt agcatttatc cttttgaatc tgctgatctc agtcgtattt gcaatcatta
    14041 tgagcgagtt gagaaataaa cgactcgtta aagtttatca aacgatgtcc ttactacctt
    14101 attttctatc ttgggtcatt atcagttact ttgtttacgc ttttttaagt cctgacaaag
    14161 gaatattcaa tcagtggatc actggacatg gaggagaagc tgtcaattgg tataatgaac
    14221 cgaaatattg gccgtttatc ttggtgttca ttggtacatg gaaagggatt ggttataaca
    14281 gcattattta ctttgcatct gttatgggaa tcgatccgac ttattatgaa gctgctatgg
    14341 ttgatggagc tagcaaatgg cagcagatca aacatgtgac gataccacaa cttattccac
    14401 taatgacgat tttaacgatt ttagccgtag gaaacatttt ccgagctgat tttggcctgt
    14461 tttataacat tcctaggaat tccggtgcat tatatgatgt gactcaagtt ttggatacgt
    14521 atatctacaa tggcctgaca tccacaggag attttggtat gacggctgct gcaggacttt
    14581 accaatcagt tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc cgacgttttg
    14641 atagcgattc tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag tggagagagt
    14701 ccaagtccgc tctttcaata agacggctaa ttttttctct aatataatga ttgcactctt
    14761 tgctatttcc tgtattttgc catttatatt tgttatcgcc atctctttta ccgatgagtc
    14821 catattgtcg actcacgggt acagtttttg gccagaaaag ttcagtatat ttggttatac
    14881 gtacttgttc gaccagatgc aggataaaat tttccaagcg cttttcgtca ctgtacttgt
    14941 tactgtttta ggtacactga tcaatagcac ggctacttct ttatatgctt atgcgatttc
    15001 acggtcaaac tttccattcc gtcgtttttt taccgttttt tgtttgatta cgatgttgtt
    15061 ctcaccaggg atggtggcca attatcttgt tatgacaaat cttcttcagt taaaagatac
    15121 gatttgggca ttgatcttgc caatggctgt cagtcccttc aatattattg tgatgcgcac
    15181 attctttaaa cgttcggtct ctgattcgat tattgaatcg gcacggatcg atggagctag
    15241 cgaactgcga atatttgttc agatcgtttt accgttagct gttccaggta ttgcgacaat
    15301 cagtttattt gccgcattgg gttactggaa tgactggttc aatgctttac tatacatcca
    15361 agatgataag ctagttccac tacagtatct tttgatgaaa atccaaagta atattcaata
    15421 tctgacacaa aattcaggag caggaagcca attgacaggc ggattagcct cagttccagg
    15481 agaatctgcc agaatggcga tcgtagtcat ctcgacgttg cctattgcga tcagctatcc
    15541 atttttccag aagcattttg tcaaaggtct aacaatcggc ggagtaaaag aataaagaaa
    15601 caaaaatata aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag aaactagcct
    15661 ttacaggtgt ttcagcgttg ttgttgggaa cattagcagc atgcggaggt tctggttcta
    15721 aagaccaggc agaagctagc aattcggaca ctttgcagat gtatcaaatc ggagataaac
    15781 cagataattt cgatcaattg atggaagtag caaacaaacg aatcgaaaaa gagatcggtg
    15841 taaaagtcaa tatcaattac attggctggg gcgattacga aaagaaaatg aacgtcatca
    15901 tttcttccgg ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc aatgcccaaa
    15961 aaggagcctt tgctgatttg actgaattag cgcctaagta cgctgaaaaa gcttataatg
    16021 atttagatga agcatatatt aaaggaaatc tggtcaatgg aaaattatat gctttcccag
    16081 tcaatggaaa tgtctttgct caacaagtac ttacttttaa caaagcttta ctagataaat
    16141 acgatctttc aattgatgga atccaatctt acgctgatgc agaaaaagtc ttgaaggaat
    16201 tccatgaaaa agaaccaaac acggcagctt ttgccattgg acaaggcttc aaagtccaag
    16261 ggaactttga ttatccttta gggaatacgt taccatttgc tattgatctg gatggagatg
    16321 attcgaaaat catcaaccaa tacgataatg aaacgtatat cggactgtta cgtacaatgc
    16381 atagctggta caaacaagga ctcattccaa gtgacgctgc aacgagcaat aaggattatc
    16441 cactagaagg aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat gattatggcg
    16501 atacaatttt gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt actgttccac
    16561 taaaatctac agctcaagca caaatggcaa attttgtcgt atcaaatact tcaaaaaata
    16621 aagaaaaatc agtagaactt ctagggctgc ttaacagtga tccagaatta ttgaatgggc
    16681 ttgtttgggg gatcgaggga gaagcatggg aaaaagtcga tggttcagat gataaaatca
    16741 aattgctaga tggttatcag ccaaatacac atatgtctgc ttggaataca ggaaacaaca
    16801 agattctata tacacaagag tctattacgg atgacatgat tgccaaacgt gatcaatcga
    16861 ttgctgatgc agaaacttca ccgattttag gattcagctt caacactgac agtgtcaaaa
    16921 cagaattaag taatatttct aatgtcatga atcaatattt agatggattg aatacaggga
    16981 ctgttgatcc agatgaaaca ttaccgaaat tgaaagacgc tttggacaag gctggctatg
    17041 ataaggtatt gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa taataatgaa
    17101 taaagacaaa ggggttgtga caaaagacgt gtcacaacct cttgttccga ataaacggtg
    17161 ttcaaaagcc agtttctcgg tattaagcta aatatatgta aaaatgtgga aagccatatt
    17221 cacaaaattt ttcttactac tcgaaactaa gcggctattt cacaaactct tggtaaacgg
    17281 tgttcaatca gctaaccctc ggtattcgct cacaaaacga caaaatatga ggaactattt
    17341 ttccgtttgt ttctctaata atcaggtcaa ggtgctgatt gcccaacctt tttttgtata
    17401 atgagaaagt ataaacttaa tgtttggagg agaagatatg ttagggaagg ttttggaaga
    17461 gttatttatc cggatctggg tcattataaa actaaccttg tatttctgga tatatacatt
    17521 tgccggcggg atcatctttg gattaggtgc ggcatggaaa acagtcaatg aactatttta
    17581 tttgtacgga ttcgagtata aagaaatcac aataaaaaga ggctggaata tatataaaag
    17641 aaatttttta agaggcaatc tgctatttag tttattttta tctggtactg ctttattgag
    17701 ttacaattta tatttatctg ttcaaatcaa agggctcatt tttttagcta ttgattttat
    17761 tttacttttt gccttgctct gcctatttgc tacttatcaa tacagtatga ttttagatag
    17821 tgaatatacg atctctgttc ctaatctgct aaagctaagt tttatttcgg ttttttccag
    17881 cttttcgtct tttctaaaaa taattattgg tagcggtata attttaggcg tgacttggca
    17941 attcaaagga ttgatcctgt ttggtgtcat tggtcttttg acggtttgga atggtacgat
    18001 gacaacacat tggcgtgaag aattagataa acagttggaa agttatgaat aagtttcgga
    18061 ttctattttc aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg gttatcatga
    18121 tcggtgtaac gatgactgct accgttattt ttagtatcca tacttgggaa caaaatcaaa
    18181 aacaggcaga aaacatgaca agtgatgccg ttcaaagcac aagcagaatg ctgaatgata
    18241 aaacaacctt gagtaggatc atcaaaaacc agcttgtagg gaattccgaa aagatcgaaa
    18301 atgtgacgac ctacttaaca aaacccatag atcagtatct gatgtatgta tacgaacagc
    18361 aaaacagtac cgatgaatta gtttctttcc caaatcaaat caaagatctc tacgcaaatt
    18421 atgaagaact aagtgcgata tatatcgtgt tgaatcaact accggagtat tatgaatctt
    18481 ctagagaaaa caaaggtggg gaaataaaaa aggggacacc aaaattacta gacgcctttt
    18541 atatcaagtt gcctatcaca caaggaggag ctgagtcagg aagtattttt attggttttc
    18601 aaaagaaaga actagatatg attttagaaa atctaacgtc attcaatgga ctctctttat
    18661 acatgatttc tggaacgaca aatcgactat acacattcca tgataataaa atagctaaag
    18721 aaacgtttga aagacaagaa atgatcatca cagagagtct gaagaaaaat tcacaattgc
    18781 cgattgacga tctggaaaaa aacaattttg ttcaacacca agaactgtct gatgattatc
    18841 gtatattagc tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa aatcttgccc
    18901 cgctgatcat tggtatcatt attttagaca atatactgct tatctttctt tataaaacat
    18961 tcaaacgata ttcacagcaa gtatctatcg tcatgcaggc catggatcaa acagcagcag
    19021 ggaatttaga gacgcggatc gacataacaa acacggaata tgaactgaag gaactttcaa
    19081 tcggtatcaa cgaaatgttg gatagcatca atcagtttgt agaagacatc tacaaattag
    19141 aaatcaaaca gcaagacgca catatgcggg cgcttcaagc acagatcaat ccacactttt
    19201 tatataatac attagaatat atccgaatgt atgcaatcag cgaaggaagt gaagaattag
    19261 cagatgttgt gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa gagaaaacga
    19321 tcactttaaa agaagaactg gacttttgcg aaaaatatgt ctatttgtat caattgcgtt
    19381 atcctaatcg agtagcctat cattttatga tcgatcctga tttggaaaag atcgaagtac
    19441 ctaaatttgt gatccagcca ttagttgaaa attattttaa acacggtatt gattttactc
    19501 gattcgataa tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta aggatcatca
    19561 tcaaagataa tggaaaaggg atgactgaaa aacggctaaa acagattgaa gaaaaactgt
    19621 ctcatcctaa agtggaactt cacggttcta tcggtctgca aaacgtgaat gaacgtttac
    19681 gtgccagctt cggcagcagt tattatatgt cgcttgagaa taatgagaca ggtggactga
    19741 ccgtttctat tacattcaag gagggatgag cgtgtatcaa gtgttattgg tagatgatga
    19801 atacatgatt ttgaatgggt taaaaaagat aattgattgg caaagtttag gctttcaaat
    19861 agtagcaaca gcagagaatg ccaaagaagg actagctgta cttgaacagc gacagattga
    19921 tttagtagta acggatgtga caatgccaga aataaatgga ctggaattta ttgaagcggc
    19981 tcaaaaagaa cgtcataatt ttgaatttat gattttatca ggataccaag aattcgatta
    20041 tttgaaagga ggtatgcaat taggcgccgt gaattatttg atgaaacccg tgaataagtt
    20101 cgaattggtt gaaagcctca agaaaatcaa aacacggtta gatcagcaaa atgaacaaaa
    20161 aaatcaacaa gaaatctatc aagaactgtt attcagtcaa tggttgaatg aagaattgga
    20221 tgaaataagt gaagaagaaa taataggaca aataagtgag aagcagcata ggatagtatt
    20281 gattcaactg gcaagaactc atgatactct tatcaataga tggttgcaag aacggcaaca
    20341 aatcttttac tatcaacgaa attacggaga ccgtgtattg atcacgttgt tgttggaggc
    20401 agatgaagtt gatggcttct gttgttttgt tcaagaaaac tttcctgatc aggaatggct
    20461 gatcagtatc ggggaagaga cagattcttt ggacaaaatc cctgaaacat tccaacaagc
    20521 gaaagacaat ctacagttgc atcaatttta tggagataaa gacgagcatg ttttttacgc
    20581 agtacaagca gaaacaaaag atcaaaccat cgatttttca agtttcagac gcgtgctgca
    20641 aaataaacaa ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac agtttcagtt
    20701 agcagccatg atgccggaag atatacgata ttccagtttt ttactgttta tggagattca
    20761 acgggaattg attgatctgg aagatgagga atatttacaa ggaatcgaaa aaatccatca
    20821 ggcaaaaacg gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa agcatcagag
    20881 acagaaaaag tacagtgaca atgtggaaaa agtaatcgta atcctgcacc agcattatca
    20941 agaaccactt acactcaaag aagtgtcaga aaacctgcat ttaaatgtca tgtatctagg
    21001 acagctgttc aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc atttacgtat
    21061 ggaaaaagcg aaacaactgc ttttgcacag taatcaaaac atcaatgaga tagcaagtga
    21121 gattggctac aacaacacca cgtatttctc taaattattc aagaaaatcg tcggcagatc
    21181 ccctaaagag taccgagaaa acagtggaga atcataaaag aaaaagccaa tgtaatgaaa
    21241 taacttataa aaaattgtct agaaatctaa ttttgggctg ttcttattac ttgaggcaag
    21301 gcagcttttt catgacctct cgataaacgg agttcaaaag ccagtttctc ggtattaagc
    21361 caaatttatg caaaaatgtg gaaagccatt ttcacaaaat ttttcttaat actcgaaact
    21421 aaacagcttt ttcacgacct ctccactaaa cggtgttcaa tcagctgacc ctcggtatta
    21481 gctcaaaaaa tggcaaaata tgaggaacta ttttgccatt tgtctctcta atactcaggt
    21541 cagaacgctg atttcacaac ctctcaataa acggtgttca aaagcttgca tctgcggtaa
    21601 taagaccaac caaacgaaaa atatgaggat ctatttttgc ttggctgttc ttattacttg
    21661 atgcaggaca gctttttcac aacctcttgt taattatagt ttgataagga aaaaggcaaa
    21721 tcttttgctt gatatttctt agggtgaggg atgatcccta attggtaaga gatcgtgccg
    21781 cctttcagca aatcttgatg ggtaaaatat aatttcgtat attctttgtc catccgtttg
    21841 attttatgga taaattgttg ctgcggccga ttaggcgttg cttcaatcgt caattccttt
    21901 ccatttgaca aaagcaaaac agccttgtca attaatggca taccgataac atattcaccg
    21961 gttccaggcg tgacaggata aaatcccaga ctattgaaga tataccaagc ggccatactt
    22021 ccattgtcct catctccagg gtaacccatt ggagaatcgt cgaaggtctg agtcatcaac
    22081 tgtttaagca gtggctgtgc catttcaggt tgtcctatat aactgaacaa gtaaggatag
    22141 tgaaaacttg gctggtttga aatagctaat tgtccaaatt ctatcgcggc catctcactc
    22201 atttcgtgga tctcaaaacc atatcctcct gggtcaaacg ttgggggctg attgcacagc
    22261 tcaatgagtt tttctttata tctctcactg ccaccatatt ttccgatcag tcctgaaaaa
    22321 tcgtgataaa cagcaaagct gctttgccaa gcacttcctt ctgcataatc ttgtccccaa
    22381 cgattagctg aaaatggttc tctgaacttg ccatctttat cttttgaacg cataaatcct
    22441 gactcatagt caaagatatt ttgatagttc aatgattgct gctgatattt cttcgtcatt
    22501 tcctcttctt ctagtacctt ggcaacttgg ctaatacaaa aatcgctata agcatagtct
    22561 aatgtgtgat tgactgattc gtggtagtga ttaggaacat agccatatgt caagtaatct
    22621 tctgttcctt ggcgtccata atttggatgt ttgctttgaa ccgtagcacc tttttccatt
    22681 gccgttagaa attcaggcat caagtctcgt cggatatctt ttacagcagc atctgcaatg
    22741 accgcatcga tcaatgtccc aggcataagt ccacgttcat caggagacag ccattttggc
    22801 aaatagccac tttctctata gctgttcaaa aaaccttcca gcatttcttc gtatttttct
    22861 acagcaatca aagaataaag aggataaacc gttttatacg tatcccaaaa cccattattt
    22921 gtatagagaa caccaggttt tatagatcga ctagtcgtat catagtggat tttttgccca
    22981 ctaggatcaa tttcataaaa tgtttgtgga aataaaaaca cccgatataa attatgataa
    23041 aacgtccgca attgttgttg atcatggtgt gtgagctgta tacgatcaaa ataggactgc
    23101 cattgttctt gactgtgagc aaggtaagtc tctttgcttt ggttttgttc tagttccagg
    23161 ttataagctg cttgttccga gctgataaaa gatgtcccaa atcggatagt ttgttttttt
    23221 gtctgttcaa aatacaacgg gatcgagtcg ctatttttgt tggaaacagc taactcatca
    23281 attgttaaag gatattcaaa tctcaatata aaataaaaag aaaaatcagg atcttctgaa
    23341 ccagcaaaat gtgtgatttt tccttccact gtgtaaggat ctataacaaa gagctgatgg
    23401 cgtcccggaa aggataaaag taaaccgctg tcatttttgc tgtaatcaat agataagatt
    23461 ccgccataca tgctaggtat caatgtagaa cagatgccat aacgtaattg acagatcgac
    23521 agatgagtcg ggcaaaatat actttcttct gggcggtaag aactttgagc atggaaaagg
    23581 gtgttctcct gtagttttcc attgatcggc gtaaacagca tatgactgaa atcacccatc
    23641 caaggacttg gttgatgggt aagacggtag ccttgaaaaa cgcggtcatc aggatgaaac
    23701 caccagctgc cgttttgatc cgtagtttgc ggtgcaaaat aattcatccc aaaaggaacg
    23761 ccagtataag gctggcagtt cccattagag aaatttggct gattcgctgt tgcatgtcta
    23821 gtatctattt gaccgatatt cattttattt ctcctttgtt gattgtcttt tgatgaatga
    23881 aactggaaat ttactatcgg atggtcgatc ttttgtctct aaccaagtga ccaaagcatc
    23941 tcccgcaagc ttacctaact gttcaaaatc ttgtgcgatg gttgtcagtg gcgggtcaac
    24001 aagagctgct gcttggatat catcaaatcc gataattgaa aaatcttcag ggatatgata
    24061 accatgctgt ctcaagagat tcatggtctg gatagcgaca acatcgtttt cacaaacaaa
    24121 agcagttact tcatacttag tgatataaga aagcaattca tctaatgtcg cgcttttgtc
    24181 atccagtgaa gtgtggaaag tcaaaccagc tttgtccaat gcttcaaggt aaccaaggta
    24241 acgctgtcga acggattgtg gatgagtctg cgtaccaaac aaataagcga tttttgaatg
    24301 tccctgttcg atcaaataag aggcagcaag cgcaccgcct tggaaattat cggaaagaac
    24361 ggtaggaaaa ggtaactcat agattttttt atctaatatg acgacaggga attctttcaa
    24421 tgaaagctca aaaagtaagt caagatgttg ttctgtatca agagcataat aaatcaatcc
    24481 gtcaaattca ttgattagct cttttgctgt tttattttgt agaaagtcaa gcgtcgtcat
    24541 catgacatca atctgtttat cttgcatcac agggttcaat cccttgctaa aatcaccaac
    24601 agacaaatca gcgacatatg gaagaagaaa cagaatccgt cgtgtttttg taggagaagc
    24661 aagaatctgt tccggagaag cggatttaac gaaactgcct ttcccgcgaa cgcgataaat
    24721 aagtcctaat tgctctaatt cagtcaatgc acgtttggaa gtgattctgc ttactttata
    24781 ggtacgtgaa agttcttttt cagttggtag ttggctgtct acaggtaatt caccagttaa
    24841 aatagccgtt tgcaaatcat taaatattgt ctggtacaat ggttgattca tataaacacc
    24901 tcttaatgat atatcatatt caaataatac cataatggat gaaaaagtaa ataaaaagat
    24961 attttttgaa agcgtagaca taattggctg tatgaagtat aatctttaaa gatatatcaa
    25021 atagaaagaa ggttttatta gtggcttata aagatatacc aaaatcggtg cagaaattta
    25081 tggaagatat cacacaaaaa tgtggggata tccatgcgga ctgggcaaag aattttacag
    25141 cagcatttgc caatactctg ttgacaacag tcaaaaagca aaatgacgga accacctttt
    25201 tattgacggg agacattcca gcgatgtggt taagagactc tactgcacaa gttcgtcctt
    25261 atttagtgat tgcaaaagaa gatgaggaat tagctgacat gatcagcggg ttagtcaaaa
    25321 agcaattttt ttatatcaat atcgatccat atgcgaatgc cttcaacgaa gaagctaacg
    25381 gtgctggcca ccaaacagat catacaaaaa tgaacgattg gatctgggaa agaaaatatg
    25441 aaattgattc tttatgctac ccaatacagt tggcctatct tctttacaaa aatacaggaa
    25501 aaactgatca attcaatcaa tcttttattg aaggtatcaa aaaaatcttg gacgtgttca
    25561 aaacagagca agatcatgaa cactctcctt atacatttgt acgagacacg acaagaaaag
    25621 aagatacgct gatcaatgac gggcgaggtg caaaaacagc ttttacagga atgacatggt
    25681 ctggtttccg tcctagcgat gatacttgcc gttatggata tctggtacca tccaatatgt
    25741 ttgcggtggt cgtgttaggt tatgtggaag aaatttttca aacgatactc gatgataaag
    25801 aaattgtaca gcaaacacag aaattgaaga aagagatcca agaggggatt cagaatcacg
    25861 gacgaacggt taatcaaaaa gggcaaacga tttatgcata tgaagtagat ggaatgggaa
    25921 acgccacagt catggatgac agtaatgtgc ccaatctgat cgccgcacct tacttgggat
    25981 attgttctga acaagaggaa gattatctgc aaacaagaag aacattgttg agtaaagaaa
    26041 atccatattt ctatgaagga aagtacgcaa aaggaattgg atcctcccat acgccagaaa
    26101 aatacgtttg gccgattgca ttagctatgg aaggaatgac aacgtcagac aaatctgaaa
    26161 aagagcggat attgaattta cttgtagcaa ctgacgcagg aacacacctt atgcacgaag
    26221 gattcgatgt gaacaatcct gaaaattata cgagagaatg gttttcttgg gcaaatatga
    26281 tgttttgcga attagtcatg gattactttg atattagagt agaaaagtag gaggtatcgt
    26341 aaatgaaaaa gaaagtatat atcatttctc atagccactg ggatcgtgaa tggtacatgg
    26401 cttacgaaca gcatcacatg cgactgattg aattgataga cgatctacta gagctatttg
    26461 aagttgatcc gtccttcaac agttttcatt tggatgggca aacgattatt ttagatgact
    26521 atcttcaagt aaggccagaa aaaagacagg caatccaaca agcaatcaat gaaggaaaat
    26581 tgagaattgg accattttat atcttgcaag atgattttct tatcagctcg gaatcgaacg
    26641 tgagaaatat gctgattggc atggaagaaa gccgtaaatg gggaacccct gtcatgttag
    26701 gctattttcc cgatacattt ggaaatatgg gacagacgcc tcaattaatg aaacaagctg
    26761 gtatttcagc agcagcgttt ggccgtggtg taaaaccaat tggctttgat aatcaagttt
    26821 tggaagcaga aaactattct tcccaatact cagagatgtg gtggaaagga cctgatcaaa
    26881 cagcaatctt tggtctgcta tttgccaatt ggtatagcaa cgggaatgag attccagtag
    26941 aaaaagaagc agctcttgcc ttttggaagc aaaaattagc ggatgcagaa caatatgcct
    27001 ctacgaacca cttattgatg atgaatggtg ttgatcatca accggtacaa aaagatatat
    27061 caaaagcaat ccatctcgca aatgaactgt ttccagatta cgagtttatt cattctaatt
    27121 ttactgacta tctggaagca gttcaaaaag atgtgccaga agacttaggc tcagtagaag
    27181 gagaattgac aagtcaagaa acggatggct ggtatacttt agccaataca gcatctgctc
    27241 gggtttactt aaaacaatgg aataccaagg tccagcgaca gctagaaaat attacagaac
    27301 cacttgcgac gatggcttat gaagttagtg gaaactatcc ccatgatcaa ttagattatg
    27361 cttggaagac attaatgcaa aatcatcctc acgacagtat ttgcggttgt tcagtcgatt
    27421 ctgtccatcg ggaaatgata cctcgttttg aaaaagcaga tgaagttgga aagtatcttg
    27481 cacaagattc cttagaacag ctgaccgcag caatcgatac gaccggattc ccaaaagaca
    27541 gctttccatt tgtcattgta aatactgcag gaatggataa aactggtgaa gcagaaataa
    27601 ccatcgaatt agaaagaaaa agattcgctg aaggaatacc tgaacaacta tatcaagagt
    27661 tagaaaattt gcctaaacgt aagtatcatg tagaaacaaa aagtggggcc actataccag
    27721 ctattttatc tgaagaaact gtccaatttg gttatgattt gccgaaagac cgtttccgtg
    27781 tgccatatat ggcaagaatg atcaaagtga ctttaccatt agaaaacatg ccagcatttt
    27841 cttgggaaac attcgcgctt gtagaagggg aagcgaaagc agaagaaaag gaaacaatga
    27901 ttcatcagag tggacgaatc atcgaaaacg gccctctaca tttgacgatt gaaaaaaatg
    27961 gtaccattac aatggaagat cgcaaaaaca aacgaaagtt gaataatctg catatttttg
    28021 aagatatcgg cgatatagga aatgagtata tctttaaaca acctttctgt gatcagccaa
    28081 tcctatccag taacaaagaa aactctgaag taaaagtatt agtagataca ccggaaatag
    28141 caaaaataag tattctacag gaaatggaaa tccctgtttc tgcagacgag cgtttagaaa
    28201 aagaacagca gatggttgtg gaatttcgtt atcgaaaagc agaacgatcc aaagaaaaac
    28261 gaatccttca aataaaaaca atcatgacaa tcagaaaaga tagtaaaaaa atcgactttg
    28321 aaacgactct cgacaatcag atgaaagatc atcgcttacg tgtcttgttt cctacaaagt
    28381 tacatgtgga acatcacgaa gcagatagta tttttgaagt ggtgaagcgc ccaaaccatg
    28441 tgtctaaaag ttgggaaaac cccacgaatc cgcaacatca gcaagcattt gtcaatattc
    28501 atgatgaaga gtacggtgta acagtcggaa actttggttt gaatgaatat gaagtaacag
    28561 aagacggaca aatcgcagtg acgctacttc gcagtgtggg agaactaggc gattggggat
    28621 attttccaac accagaagca cagtgtctag gtgagcatcg gttcaattac agcattgaac
    28681 tacatggacc agaagaaaaa ttctctactt atttgcatgc atacgcagca cagattcctt
    28741 tttccactca acaaatcaaa catcatgaag gaacattgat ttcaaaacaa caatatttaa
    28801 cgataaaaag tgaaacgttt gcaattacag ctttgaaacg cagcaagttt agtgataaag
    28861 tagtagtaag aggtttcaat atgtctagtc atttagaaaa attggaaata actaaagaca
    28921 atggaaaaac tgtcatattg aatctgcttg aagaaccaac gaagcaagcg gttgtcccaa
    28981 taatccaacc ttatgagatt cggacaatcg gattcgagga ggaaaacgaa tgtatggcgg
    29041 aatagaagca ggcggaacaa aatttgtgtg tgcggtttca gatggtggag aaattttaga
    29101 aaaattaagt atccctacca caacaccaga agaaacattg gatcaggtat ttgaattttt
    29161 tgatcgttat gaattgaagg gaatcgggat tggctcattc ggcccgattg gtatcgacaa
    29221 aacaaaagat aattacggat acgttttggc aactcccaaa aaagggtggg cacaattcga
    29281 ttttcttggc acaatcaagg aacgctacaa tattcctgct gcttggacaa cggatgtcaa
    29341 tgctgctgca tatggggaat tgaagcaagg agcagcacaa ggaaaaaata gttgtattta
    29401 ccttaccgtg ggaacaggaa tcggtgcagg tgtcgtgatc aatgaagaaa ttttttcagg
    29461 gatcgcacat cctgaaatgg gacatatttg ggtgaaacgc catccagatg accattatga
    29521 aggtacttgt ccttatcata aagattgttt agaaggatta gcagcaggac cgtctattga
    29581 ggcacgcaca gggatcaaag ggcaagatct gccgcaagat catcctgttt gggctattca
    29641 ggcttattat attgctcaag cactgatcaa ctatacgttg acgttagcac ctgaaaagat
    29701 tattttaggc ggtggggtaa tgaatcagga tcatctcctt caaaaaatcc gtcagcaatt
    29761 tgttgaattg atgggtggtt atatggaaac acctcaagta agtgaatata tcgttcgttg
    29821 gggactgccg aatgaaagtg ggattatcgg tagtttgctg ttagcagaac acgaacatca
    29881 aaagtaagca gacaaattac acaaaaagaa cagagtctta tcattatctg ctgataagac
    29941 tctgttcttt tttatttcta ttcccataat ccaggtaaag ctttaccgac tattttttct
    30001 tgagtaaatg gatggatcat gtgcagttct aatgcatgga gcatcagtcg ttcagctgtt
    30061 ctattttggt agagagggtc tccaacgatc ggatgtccct tatgagctaa atgaactctg
    30121 atctggtgtg tacgtccggt ttccaaaaca caatagactt gtgtttgttc agaaagtact
    30181 ttgttgacag tgacatgtgt caaggcgctc tgaccatttt tatcatctac gacccttttt
    30241 ctccgatcat ggcgatctcg tccaatttta ttggtgatgg tcatatcttt ggcaatttct
    30301 ccccatacga tggcttgata tctccgatag atcatttttt gttccaacat tcttccaagt
    30361 atcggcaaga caaatggatt ttttgcaaat aaaacggcac cgcttgtttc tttgtccaag
    30421 cggtggacaa cgtaaggtcg ttgctgttta gtgtcgagat aagcagctaa atgattgagt
    30481 aaggtactgt tttctgtcgg ttcatttgga tgagtcttca ttcctgcagg cttatccact
    30541 ataatcaaat gctcatcttc atataaaaca cggatgtgct tcgcatctcc taattgaact
    30601 tcttgataat tataatctgt ttcttcgaat aacaatgtga tctggtcatt gccctttact
    30661 tcatgatgga acaaagcagg ttgttgattg atccaaacgt ttttacgtat acgcaaaaag
    30721 tgtcgaacct ttctaggaac taaccattcc ttttcaagca agtcgcgaat tgttgtttca
    30781 ggatggttca taggtaaagt gatcgtgatt ttcacaagtg tactcctttc agtgcaatcg
    30841 cagactaatt gtaccatttt taaaacatat ttaagaaaaa acttacattt ttctgttcat
    30901 tcttatgtta ctctacttgc actaacgtaa aaaaacatat tgaactacaa cttaagcagg
    30961 aagaaaacac tctttcacta tggtaaaata agacgattga atcaaataga caggagaaga
    31021 agcaaatgga ttttcaaagc attttagaaa agataaaagc tgctttgatc agtttttggc
    31081 gttggatcag accatatctc ggacaattcc atcgatggcg aaagcgcatc tggaaaaaat
    31141 atcatgtgaa caaattgatt ttgctgattg gtttgatctg tgtcttagtg acaagtatct
    31201 acctctttat tttagcaaaa caagcaaatg tcgaaacgtt aaaatcagga ttaagccaat
    31261 cgacagtcat ttatgataag aaaaacgaag aagctggcac actgtacgcc caaaaaggaa
    31321 catatgtaga attaaacgcg atttctccct atatccaaga tgcagtaatc tcgacagaag
    31381 ataggaattt ttacgagcat cacgggtttg atatcaaagg gattgcccgt gcagcagtcc
    31441 gaatggtctt gtctggcgga acatcagggg gcggaggaag tacgatcact cagcagcttg
    31501 ccaaaaatgc gtatctgaca ttagaccaaa cgtttgatcg aaaagcgaag gaattatttt
    31561 tggcaatcga gatcgaaaag aagtacagca aagaagaaat cttgaccatg tatcttaaca
    31621 atgcctattt tggcaacggg gtatggggtg tccaagacgc ttccagaaag tattttggag
    31681 tagatgcaac gaatgttacg ctgtctgagg ctgctacttt ggcaggaatg ctgaaaggtc
    31741 ctggtattta taatccgatc gatcacccaa aaaatgcgaa tgatcggaaa aacacagtac
    31801 taagtgtaat ggaagaaaac ggaaaaatca caaaagaaca agaacaagca gaaagccaga
    31861 cagatatcag cgcgtatctt aatgacacat acgataattc agattctggt tatcgttatc
    31921 cttattattt tgatgcagtg atcgatgaag cagttaacga gtatggtctt gatgaagaag
    31981 atgtcatgaa taaaggctat aaaatctata cagctttaga tcaggattat caaaagcaat
    32041 tagaagctac ttatcaaaac agtgcattat tcccagcaaa tgcttcagat ggtgccatgg
    32101 tccaatctgc ttcagtagct ttagatccga atacaggtgg tgtacaagca ctagtaggac
    32161 gaagaggaga tcatgtcttt agaggattca gctttgctac acagatgcgt cgttcaccag
    32221 gatcaacgat caaaccatta agcgtatata caccagcact ggaagctgga tacaagcctt
    32281 ccagtatctt gaaagacgaa ccgcaaagtt attacgatgc gcataatttt gacgggacat
    32341 accaaggaga agtaccgatg tatcaagctg ttgcacaaag tttgaatttg cctactgtat
    32401 ggcttttgca tgagatcggt ttacaaaaag gatatgataa agcagaagaa ttcggcctgc
    32461 ctttagcaaa atctgataag tattatggct tagcccttgg tggactggaa aaaggagtat
    32521 ctccattgat catggcgggt gcttacagtg catttgccaa tgatggtcag atgtatacgc
    32581 cgcatcttat cacgaaaatc gttgattcga ctggagcggt gatcgtcgat aacacaaaca
    32641 aaaaaccaaa acaggtcata tcaaaggaaa cagccgatga aatgaccagc atgcttcttg
    32701 gtacattttc aaatggaaca gcggctgctg cgaatcctgc aggttatacg atagcaggga
    32761 aaacaggagc cacagaaact aatttcgatg ccacaaaagc aaatgaccaa tggatgatcg
    32821 gttacacgcc agacgtagtg atttcgacat ggatgggtta cgaagaatcc agcaagctgc
    32881 actatttgga agggacaagt ggaaatgttg tcgggaaagt cttcaaatca gcggcagaag
    32941 gcatccttcc gtatacttca aaaacaggat ttagtgtagc agatgcctat gccacaggag
    33001 gacaagtggt agctgcagat caagttggaa acacaggaaa ttctaatgga gagtctggaa
    33061 attggcaaga taacttgaat caatatggtg aacaagcaaa agaagggctg aaaaacttcg
    33121 gcgatatggt gaaagaaggc gttcagggaa ttggtgaagc ggctaaagac ctctggcgga
    33181 aatatcaagg agagtagccc ctttgaaaac gaataacccc atgttacaat agagagtaac
    33241 tactaaaaga aaagagggca taacatgtca aacatctacg atagcgcgaa tcaaatcgaa
    33301 cgtgagatcc gtgaattacc agaattcaaa gcgttgaaag aagcgtacga gaaagtacaa
    33361 gcaaacgaag aagcacacaa actgttcaaa gacttccaag cgatgcaaat cgaattacaa
    33421 gaaaaacaaa tgagtggaca agagttcagc gacgaagatg caatgaaagc acaagaaatg
    33481 gctgtgaaaa tccaatcaga agaagtaatc aatgacttga tgcaaaaaga gcaaggcttc
    33541 agtacaatca tcaatgactt gaaccgtatc atcatgacac cagttcgcga cctttacagc
    33601 gaataaaact attttatgaa acaacagagg gtgtgaaaga gacgttcggc cttgagcgat
    33661 gacaaaattg cttcttattg ccgataggct gtctcttgaa caccatttac caagaggtcg
    33721 tgagcctacc gtttaactct gagttacaag gaacaatttc aaaaaacagc ttctcatgtt
    33781 tgatgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt attcagaaat
    33841 a
//
LOCUS       DASHWW010000022        32790 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.022, whole genome shotgun sequence.
ACCESSION   DASHWW010000022 DASHWW010000000
VERSION     DASHWW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.022"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..712
                     /locus_tag="U2R64_001239"
     CDS             <1..712
                     /locus_tag="U2R64_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918070.1"
                     /translation="YYIFSLFNSRNYTNENMELLRKDFEVVYKNFVLNDLSLNELILQ
                     IISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYLLSEKEQLLYGKIVEILEE
                     WKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFVVSESSVKQFFYRTQFHLY
                     AEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQNGLETEKTKIYPISLKGAN
                     IHLYHIAQELHLLKKHIS"
     gene            933..2696
                     /locus_tag="U2R64_001240"
     CDS             933..2696
                     /locus_tag="U2R64_001240"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HEM8918071.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            2780..3238
                     /locus_tag="U2R64_001241"
     CDS             2780..3238
                     /locus_tag="U2R64_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEM8918072.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            3347..4030
                     /locus_tag="U2R64_001242"
     CDS             3347..4030
                     /locus_tag="U2R64_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEM8918073.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            4177..4791
                     /locus_tag="U2R64_001243"
     CDS             4177..4791
                     /locus_tag="U2R64_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEM8918074.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            4807..5013
                     /locus_tag="U2R64_001244"
     CDS             4807..5013
                     /locus_tag="U2R64_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918075.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            5554..6684
                     /locus_tag="U2R64_001245"
     CDS             5554..6684
                     /locus_tag="U2R64_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEM8918076.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            6776..7531
                     /locus_tag="U2R64_001246"
     CDS             6776..7531
                     /locus_tag="U2R64_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8918077.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            7589..9628
                     /locus_tag="U2R64_001247"
     CDS             7589..9628
                     /locus_tag="U2R64_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HEM8918078.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(9737..10888)
                     /locus_tag="U2R64_001248"
     CDS             complement(9737..10888)
                     /locus_tag="U2R64_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEM8918079.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(11042..11572)
                     /locus_tag="U2R64_001249"
     CDS             complement(11042..11572)
                     /locus_tag="U2R64_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEM8918080.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(11671..12021)
                     /locus_tag="U2R64_001250"
     CDS             complement(11671..12021)
                     /locus_tag="U2R64_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEM8918081.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(12178..13707)
                     /gene="ahpF"
                     /locus_tag="U2R64_001251"
     CDS             complement(12178..13707)
                     /gene="ahpF"
                     /locus_tag="U2R64_001251"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEM8918082.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(13717..14280)
                     /gene="ahpC"
                     /locus_tag="U2R64_001252"
     CDS             complement(13717..14280)
                     /gene="ahpC"
                     /locus_tag="U2R64_001252"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEM8918083.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(14424..15086)
                     /locus_tag="U2R64_001253"
     CDS             complement(14424..15086)
                     /locus_tag="U2R64_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8918084.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            15270..16916
                     /locus_tag="U2R64_001254"
     CDS             15270..16916
                     /locus_tag="U2R64_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEM8918085.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            16907..17989
                     /gene="uxuA"
                     /locus_tag="U2R64_001255"
     CDS             16907..17989
                     /gene="uxuA"
                     /locus_tag="U2R64_001255"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEM8918086.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(18097..19650)
                     /locus_tag="U2R64_001256"
                     /pseudo
     CDS             complement(18097..19650)
                     /locus_tag="U2R64_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            19798..20939
                     /locus_tag="U2R64_001257"
                     /pseudo
     CDS             19798..20939
                     /locus_tag="U2R64_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(21065..22144)
                     /locus_tag="U2R64_001258"
     CDS             complement(21065..22144)
                     /locus_tag="U2R64_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8918087.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(22247..22687)
                     /locus_tag="U2R64_001259"
     CDS             complement(22247..22687)
                     /locus_tag="U2R64_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8918088.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(22744..23154)
                     /locus_tag="U2R64_001260"
     CDS             complement(22744..23154)
                     /locus_tag="U2R64_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEM8918089.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(23334..23768)
                     /locus_tag="U2R64_001261"
     CDS             complement(23334..23768)
                     /locus_tag="U2R64_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8918090.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(23868..24716)
                     /locus_tag="U2R64_001262"
     CDS             complement(23868..24716)
                     /locus_tag="U2R64_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8918091.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            25105..26871
                     /locus_tag="U2R64_001263"
     CDS             25105..26871
                     /locus_tag="U2R64_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEM8918092.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            26973..28232
                     /locus_tag="U2R64_001264"
     CDS             26973..28232
                     /locus_tag="U2R64_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8918093.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            28379..29680
                     /locus_tag="U2R64_001265"
     CDS             28379..29680
                     /locus_tag="U2R64_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918094.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            29683..30534
                     /locus_tag="U2R64_001266"
     CDS             29683..30534
                     /locus_tag="U2R64_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918095.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            30547..31362
                     /locus_tag="U2R64_001267"
     CDS             30547..31362
                     /locus_tag="U2R64_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HEM8918096.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            31513..32679
                     /locus_tag="U2R64_001268"
     CDS             31513..32679
                     /locus_tag="U2R64_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8918097.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        11094 a         5809 c         6219 g         9668 t
ORIGIN      
        1 ctattatatt ttttctttgt tcaacagtag aaattatacc aatgagaaca tggagctgtt
       61 aagaaaagat ttcgaagttg tttataaaaa ttttgttctc aatgacctat cactgaatga
      121 attgatttta cagattatta gtatcgctga aatcgacgat gcagaaaatt ttattttcaa
      181 gcaatccttt ttacaatttg tccgtacgtt gtgggcagat ggacaagtat ttttaccgga
      241 aaggatctat cttctatcag aaaaagaaca acttctgtac ggaaaaattg tagaaatatt
      301 ggaagagtgg aaaaagaaaa atcaaatcca actaagatgg aatgaaaatt tcattcgaaa
      361 attcgtcaaa agtctttctt tgatcaacag tgaacaagcg gggagacagg aaatagaaat
      421 ttttgttgtt tcagaaagtt cagtcaaaca atttttttat cgaacccaat ttcatttgta
      481 tgcggaagaa ggcatcgctg aaataaatcc tattttattt cgttcattag aagaattgcc
      541 tgatgaatgt ctatgtgcga aaaaaagagt ggttttgtgc gatgctgcta gctatcaaaa
      601 tggattagaa actgaaaaga caaagatcta tccaatctca ttaaaaggtg caaacatcca
      661 tttgtatcat attgctcagg aacttcacct attaaaaaaa catatttctt gatgagacct
      721 taattaggag accttctaca aagcttttta attgtctgta gaaggttttt atttgagtcc
      781 tgattcgtgc gaagatctac ttatataaca agctttctct gaaatttttt taaaatgcta
      841 ttgacttaga gtcaactcta agtagtagaa tagataaagt gtaacaaatc tattttcatt
      901 aaaagaagat agtacggagg agagaatgta ttatgagtac agtattacat gtattggatg
      961 caatcaatag ccccgcagat gtcaaaaaat tatctgttga ggaaatgaaa cagttggcag
     1021 aagagatgcg ccaaaaaatc ttgcaaaagg acagcgatgt aggtgggcac gttggtccga
     1081 atctaggtgt agtagaatta acgattgcgt ttcattatgt atttgattca ccaaaggata
     1141 aaatcgtttg ggatgtttcc catcagtctt atggtcataa gcttttaact ggtcgaaaaa
     1201 atggttttga aaaaggacat taccgtgaag tgagcggata ttccaaccaa catgaaagta
     1261 aacatgacta ttttacagtg gggcacacat ctacatctat cagcttagca acaggtttag
     1321 ctaaagcgag agatctgaag aaagaatcag gaaatgtggt agcatttatc ggtgacggct
     1381 ccctaagtgg tggcttagct tttgaaggat tgaacaatgg tggtgtttta caatccaatc
     1441 taatcgtatt agtaaacgat aatgagatgt ctattgatga gaatcatggc agtttatata
     1501 aaaacttagc tgagcttcgt caaaccaacg gtaaaagcag caataaccta tttaaagcaa
     1561 tgggatttga ttatcgttac gtggataatg gaaacgatct ggaaacggtg atccgtttat
     1621 ttgaagaagt aaaagatatt gatcatccga ttgtacttca cgtccatacg gaaaaaggtc
     1681 gcggttatca gccggcaatc gataataaaa tgaaatatca ttggcatgta ccatttgatc
     1741 tgtccaccgg ggaggcaaag caagtaactt ctggagaaac atttaatatg atcatcatgg
     1801 attatttgga taagaaaatg caaacaagta cagctcctat tgccgcagtc aatgcagcga
     1861 taccaggcgc ctttggactg aaaacattcc aagaaaaaca tccagatcat tattttgacg
     1921 tggggatcgc tgaacagcac tctatcactt tcgcttctgc tttggcttct cagggagtac
     1981 gtccagtcgt cttccaatca agtactttct tgcaacgggc atatgatcaa ttatcacatg
     2041 atttagcgat caacgagaat ccagtgatta ttttagtcgg tggcggaacg atctcagcta
     2101 gtgaccgaac acaccaagga acatttgaca ttccttactt atcaagtatc ccgaacatca
     2161 aatatcttgc tccagcaaca aaagaggata tgatctctat gctagattgg gcgttcgaac
     2221 aaacagcgca gcctgtagca atccgaattc ctacacatgg tgtagaacat ggtacagcta
     2281 tcgcaaatga ttatagtatt ccagcctatc aaacagtaaa taatggagga aaagtagcaa
     2341 ttttagcttt aggcggtttt cttgaattag gaaaagaaac agtaaaagct tttagaaaaa
     2401 aaggaatcga agcaacgttg atcaatccag gaacgatcac agaaaatgac gtagaaacat
     2461 tagataaatt aaaagaaaca cacgaattag tcatcacatt agaagatggt agtttgtcag
     2521 gaggatttgg cgaaaatatc agtcgttatt atggtgattc ttcaatgaac gtattaaatt
     2581 ttggtgcaga gaaagaattc acggatagcg ttcctgtagg gcagctttat gaacgttatc
     2641 atttaacacc aaaacaaatc gttgaagata gtctgcgtgt cttgaatatt caataattca
     2701 ttatgctcac catccagata attgtttata ctagtatctg gatggttttt tcattataaa
     2761 aagcaaaggg gtggatgtta tgtatcagca agtagaagaa tatgtcaaaa agttccaaga
     2821 aaaatatcct agttatcaat cagaaaaatt aggtttcttt tcatttgggg atacagaaaa
     2881 aatggcagac gagttgagcg aactagttgt aaaaaagata aagactggta catcaagtgg
     2941 ttacgatctg tataaacaag agaatgagcc tttaccaaaa gttggtcaat tagacgtggt
     3001 cctgaatgga aaaaatgaac cagtttgtat catcaaaaat ataaatgtga ccatcttgcc
     3061 ttttagtgaa gtcacgaaag agcatgcttg gaaagaagga gaaggggatc ggacattagc
     3121 ttattggcgg aaagtccatg ctgagttttt taaacatgct tataaagaag cgttgaacat
     3181 agaatttaca gaagagaagc tggtcgtata cgaagaattt gaagtaattt tcttttagta
     3241 agaaaggtct gctgaaagaa atagctcatt attgtctcct gaatagaaaa gggttacatt
     3301 tttatatgaa gctgtatttt tatataacat tactggagga gatattgtgg atacactgga
     3361 acaaatcaaa ggcggagtcg tcgtttcttg tcaagctttg gaaaacgagc cgctacacag
     3421 ttcttttatt atggggagaa tggctttggc tgcaaaagaa ggcggagcag ttggtattcg
     3481 agcaaatacg acagaagata tcaatgaaat caagcgaatc gttgatttac cggtaatagg
     3541 gattatcaaa agagattacg atgggtcaga agtgtttatt actgcgacag aaaaagaagt
     3601 ggaagaactt ttggagacgc aagcagaaat cattgcactg gatgcaactt ctcgtaaacg
     3661 tccgacagaa aaaacaactg ctgaacttgt ccaaatgatt cacgaacacg gtcggttagc
     3721 tatggcagat atttcgactt ttgaggaagc gcttcaagcg caagaagatg gttttgatct
     3781 tttgtctacg actttagcag gctatacaga atattcacga aagacgcaga cacctgattt
     3841 tgatttattg aatcaaatca tagaacaagt cgatatccca gtaattatgg aaggacatac
     3901 tgactctcct gaacaagtag agaaagcata tgaattaggt gctttttcag tcgtagttgg
     3961 atctattatc acccgtccgc aattgatcac taaaagatat gtcgaagccg caagtaaagc
     4021 aaataactaa aaaacacgca cggcacagat tcttgacaaa aaagaaaaat tgatagatag
     4081 tttaaagcag attctaagaa gatgaaaaaa gcattacttt tcattttgtc ttcaagatct
     4141 gctttttaac gaattttata gaaagaaggc gaaaccatgt ttgaacggag tccttcagaa
     4201 ttgacagaac gtgaaaatta caagttgctg attggttcag tcatccctag accagtagca
     4261 gtagtaacga ctaaatcagc aaaagatata gtgaatatcg cacccttcag ttacttcaat
     4321 atcgtcagtt cgaatcgacc catcttatcc ttggcgatcc agagaaaaca agatgcagta
     4381 aaagacacag caaagaatat tcttgagaca agagaagctg ttatccatat ccttgatgag
     4441 gacaacgtag aagaagtaaa taaaacagca gccaatctgc ctaatgagga aagcgaactg
     4501 tacctgactg acttgacttt aactgattca gtaatcattt cagtaccagc attgacagaa
     4561 gcaaaagttc gttttgaaac atccttatat gaacatgtcg agatacggaa taaaaataaa
     4621 gtaacagctg atttattttt gctagaagta cagaaatatc atttaaatga aacagtctat
     4681 gatgataaga caggaaggat cgatccaaga aaattgaatg ctgtaagccg tttggcagga
     4741 aatgattatg cagcaatagg agaaattttc acgattgcac gtcccgaata aaaaggagca
     4801 ctagttatgt taaaaataag ctataaacca tcgacagatt caaaagaaat gaaaaaagaa
     4861 tatgaaacag tgaatgattt tctgcaaggg cagtacttag aagttccgcc attgcaagac
     4921 cattttgtcg ttactactgt tactttagat ggtaaggaaa tagaaatgcc agatcaaacg
     4981 attagcggat tgtttaatta ctttaacaaa taaatattta ttccgaaaag tgaaaaaaca
     5041 tataaaaaaa cacataaaac taaaaaatta tcaaagaatc ctggtgcaac tgaaagaatt
     5101 tgcaacggga ttctttcaac ttatttgtta tttttttcta aaaaatatta aagattgtta
     5161 aatttcacta tttcatttca aattccattg cctaatcatt aggaaaagtc tatcatgaac
     5221 tcgtaaatag aatatagtaa taaccttgtt aggtgaggct cctatacaaa cataggctgt
     5281 tgcccagaaa cgtcgaaagt cgccaatggg taaaacagaa actgttggat taaggctttt
     5341 tccaatagct aagaatgttt tctttacgtt gtatagtgct aaaactcgga cgatgagatg
     5401 atgctaggtc agaattcttg ttcgaaaagg tttctgacct tttctttata tttttgtgac
     5461 tgacttattt gatgagacaa actcgctcct cacctgacaa gtggattgct gtgtgaggag
     5521 gagatgcggt gaaaaaagat cgattggtgg attttgggtc cttatttgac tttgtccatg
     5581 atcggtcttt tagaagtata cagtgccagt tcttatcgtt tattgcaagc cgatgaaaat
     5641 acaaaaagtc tattattgcg tcaactaatt ttcatatttt tgagttggag cgtgatcttc
     5701 ttagctcgtt cagtcaaact acactattta cttcacccta aaatagcagg atacggttta
     5761 gccttatcga ttttcttttt agtattagta agaataggga tattcggtgt cactgtcaac
     5821 ggcgcacaac gttggatctc tctgtttggc attcaattcc agccttctga actggcaaat
     5881 ctttttttga ttttttattt aagctggttt tttcgtgacg gaaatagtag cccaaaagat
     5941 ctaaaaaaac cattcctgat tacagtaggt ataacttttc tgattttatt tcagccaaag
     6001 attgctggag cattgatgat cctttcgatt gcgtgggtca tattttgggc agcggcggtt
     6061 ccatttaaaa aagggatcta tctaatcgtt actttttctg cattgctgat tggagcagca
     6121 ggcggggtat tatatttagg aaataaaggt tggcttccac agatgtttaa tcatgcttat
     6181 gaaaggatcg cgactttaag agattctttt atcgatagtc atggtgcggg ctatcaaatg
     6241 acccattcgt tttatgcact atataatggt ggcatatttg ggcggggatt aggaaatagt
     6301 atcacaaaaa aagggtatct tccagagaca gaaacagatt ttattttttc gattattaca
     6361 gaagagcttg ggctaatcgg tgcattgtgt gtgcttttct tattgttctc attatgcatg
     6421 agaatctttt gtttaagcag tcgctgtaaa aatcagcaag ctggattgtt tcttttagga
     6481 ttcggaactt tgctattcgt tcagacgata atgaacgtgg gaagtatcgc ggggctgatg
     6541 ccaatgactg gtgtgccatt gccatttgtt agctacggag gaacaagtta tctgatcctt
     6601 tctttaggaa tcggaatcac gttgaatatt tcttcaaaga tacaggccga agagttggcg
     6661 ctctatcgac ctgaaaaaca ataaagagaa actgagaaac tctcagtttg aattatcata
     6721 aagtacaatc ttttattttt caagcgagag gttcttttag aaagaggaat tcgcaatgaa
     6781 agtatctcaa aaaatcatat tatctatttt gttactgctt acattagtag ttggctattt
     6841 ttcgattgag tttatccatg gattttcgtc tgcaaaacag agttcaactg tgaaaaaggt
     6901 agagccgaaa agtatcccta ccacactaaa tgtggctttg attggttcag atgctcgttc
     6961 gaaagacgaa aacggtcgct cggattcact tctggttgca caatacaacc agaaaacaca
     7021 acaagcaaaa ctgatctcta tcatgagaga ttcatatgtc gatattccag gttacggaat
     7081 gaataagata aatgcagctt actcttatgg gggagttgat ttattaaatc aaacattaaa
     7141 ggaaaatttc aaatttgaag ctccctatta tgcaagtatc acatttcaag attttatcga
     7201 ttgcgttaat gaactgtttc ctggtggagt caagatcgat gcagaaaaat ctctagattt
     7261 agatggcgta tatataaaca aaggagagca agtgatggat ggtaatactt tactccagta
     7321 tgctcgattt cgggaagaca aagaaggaga cttcgggagg atcagaaggc agcagcaagt
     7381 gatcaaagct atctctcagc agctgaaaga cgtaacttca atattcaagc tacccaaagc
     7441 ggttgggaaa ttacttggta gtatccaaac gaaccttcca gaaagtgtgc ttctggattg
     7501 tggtatggat ttcctcaaag acatatgtta gaataaacag gtataaatag tgaaataaag
     7561 gaatgacaag caagagaagg aggaaaaaat gaaaagaagt gacaagcacg gcaaaaatcg
     7621 aacaggcgct tatattgccg gcgcagtgat cttaatagca gctgcgggtg gcggttattt
     7681 ttactaccag cactatcaag aaacccaagc agtagaagct ggagaaaaga cagttgagca
     7741 atttgtccaa gctttgaaca agggagatta taacaaagct gcagaaatga catcaaaaaa
     7801 ggcggcaaat aaaagtgcat tatctgaaaa agagatctta gataaatacc agaatatata
     7861 cggtgctgct gatgtcaaag gacttcagat atcgaatcta aaagtagata aaaaagacga
     7921 ttctacttac agtttttcat ataaagcaaa gatgaatacc tcattaggtg aattgaaaga
     7981 tctttcttat aaaggaacat tagacagaaa tgatggtcaa accacgatca actggcaacc
     8041 caacttggtt tttccagaaa tggaaggaaa tgacaaagta agcctgacca cacaagaagc
     8101 agcaagaggg aatattatag atcgaaatgg tgaaccatta gcaacaacag gcaaactaaa
     8161 acaattagga gtcgttccaa gtaaacttgg agatggaggc gaaaaaacag ccaatatcaa
     8221 agcgattgct tcctccttcg acttaacaga agatgctatc aatcaggcga tttcacaaag
     8281 ctgggtacaa cccgattact ttgtcccatt gaaaatcatt gatggagcaa cgccagaact
     8341 tccagctgga gctaccattc aagaagtaga cggcagatat tatcctttgg gtgaagcagc
     8401 tgctcagctg attggttacg tgggagatat cacagcagaa gatattgata agaatccaga
     8461 attaagcagt aatggaaaaa tcggtcgctc aggtttggag atggcttttg ataaggatct
     8521 tcgtgggaca acaggtggga aattaagcat tacagatgca gacggtgtag agaaaaaagt
     8581 tctgatcgaa catgaagttc aaaatggcaa agatatcaaa ttgacaatcg atgcgaaggc
     8641 acaaaaaaca gcttttgaca gtctaggagg aaaagctgga tcaactgttg cgacaacgcc
     8701 aaaaaccggt gatcttcttg cgcttgctag ctctccaagc tatgatccaa acaaaatgac
     8761 aaacgggatc tcacaagaag attacaaagc ttatgaagaa aatcctgaac atccattcat
     8821 cagccgattt gcgacaggtt atgctcctgg atctacgttt aaaatgatta cagcagcaat
     8881 cggtctcgac aacggcacta tcgatccaaa tgaagtgttg acgatcaacg ggcttaaatg
     8941 gcaaaaagac agttcttggg gatcttatca agcaacgcgt gtcagtagtg atgtatcaca
     9001 agtagactta aaaactgctt tgatctattc cgataatata tatgcggcac aagaaacgtt
     9061 gaaaatgggt gagaaaaaat ttcgtacagg cttagataaa ttcatttttg gtgaagacct
     9121 tgatttgcca attagtatga atccagcaca aatttctaat gaagatagct ttaactcaga
     9181 tatcttgcta gctgatactg gatatggaca gggcgaactt ctaattactc ctatccagca
     9241 agcagcaatg tattctgttt ttaccaacaa tggcacactt gtctatccta aattgattgc
     9301 agataaagag acaaaagata agaagaatgt catcagcgaa acagcagtac aaacgatcgt
     9361 gccagatctg agagaagttg tgcaagatgt aaatggtaca gcacattctc tttctgcttt
     9421 agggattccg ttggcagcga aaactggtac agcggaaatc aaagaaaaac aggatgtaaa
     9481 ggggcaagag aacagtttct tgtttgcttt caatcttgat aaccaaggtt atatgatggt
     9541 cagcatgttg gaaaataaag aagatgatga ttcagcaacc aaacgagcat cggaactatt
     9601 gcaatacctc aaccaaaatt atcaataaaa aattgctttt taagtacagt aaaaggactg
     9661 tggcgttatc gtcacagtcc ttttttcaaa taaacggttt tcacgatgtc tctttcacaa
     9721 cttctttttg atttactcac acttcataaa ctttttttgt aaaatatttg agaacaagtg
     9781 gagaaataag tgtacttaat aaaatcacga taactaaagg tgaatagtac tgtggttcga
     9841 tcaattgact ttgctgtcca atttgtaaaa tgatcaaagc catttctcca cgcgaaatca
     9901 taccagcacc gaccatcaat gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat
     9961 aacctccaag caatttggtc aaaatcgcta caagcgtcaa tatagaaata aagagtagtt
    10021 gttcactaaa gtcagaaaaa tcaacttcta atcctacact gacaaaaaat actggtataa
    10081 atactgcata tcctaaagcc tctacattgt ggtatacttc ttctttaacc tttgtctgac
    10141 tgacagctat cccagcaaaa aaagcaccaa tgacagagct aagcccaaca agatccgcta
    10201 cgtaagacat tcctaaacaa ataactagcg atacgatgat aatagaagaa tttgcgtaca
    10261 ctttttctgc aaatgaaagt aggaaaggcg caatccattt gactaataag aaaataaaaa
    10321 caaaataaat tagctgttca atcaaaacaa gcggtaaaga agcattgcta gaagcttccc
    10381 ccgttagaaa agataggctg aaacttagaa ctaaaacgac taaaatgtca tctaccacag
    10441 aagcacccaa aattgttgat ccttcttttg tattcactac gtttagttct tttaatactt
    10501 ctactgaaat actgacagaa gttgccgcaa gaataatccc aaagaaaatc gcttcatttc
    10561 ccgaaacttg gaatgctttg cctgtcaacc agccaaaaac aaccgggaag atgatcccaa
    10621 gcaaagcaac gaacatacca ggtcggaaat attttttcaa aagagataaa tcactttcca
    10681 gaccagctaa aaacattaat aagatcacac caatctccga aaagtcatgg actagaatat
    10741 caggtttgac ccaattcaat ccagcttggc ctagcaaaac accaacaagt aattgtccaa
    10801 tcactgctgg gatacctaat ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata
    10861 tcaggcataa aataccaata aattccattc tcatcattcc tttgtataaa atatagcccg
    10921 aacttagcat aacatacatt attgaaaaaa taggaaaata tactcacaaa aaaaccaaca
    10981 atccaaaaga tttttttgga ttgttggttt ttatacggtc tattttaata actaaaaatg
    11041 attaacgtat agtcattttt cttattctga tgaaattgat aatctcctgg atgcccatga
    11101 aaatcaaaat aaagccgaat atttggaata gaagcatcaa acttttgaat ggattgaaca
    11161 ataagacgaa tccgccaatc aacaacagaa tactactata aacactccaa cttttagctt
    11221 ttgtattcat gctgaagaac aactggaaca agctgttgat gataacagct aatccaagaa
    11281 gaatcggcag gatagaaacg attgcaggtg caaaagcata gacgatcaga gctaagatca
    11341 ggaaaaaaag accactgaac agaccgatac tccaagaacc tgttttcctt ttaaaacggt
    11401 aagcctcaaa aagattcaac aacccaagca aaacaagata ggcggtgatc agataaccga
    11461 taaaatgaaa aacagcagaa gggtttagca caatcgcaat cccagaaata atataaacag
    11521 cagctcttaa taaggcgtat ttttgaatat tttgtttaat cgtctcaaac atataagaaa
    11581 acctcctttg acttatttta acgtgaacta gtcattttac caaattaaat gttacaaaat
    11641 gagcgaagga gaagaatatc tctggaaaaa tcaacttctg aggatctttt ccattttttt
    11701 gccttttgct agctcatcga tcattttatc taaataacga atttctttca tcaagttatc
    11761 ctcgatgtct tctactcgta caccacaaac aacacctgta atcaaggaac gtgaaggatt
    11821 ggggacaggg gcttccgcaa aaaattgttc gaaagtcact tgtttttgta gttgatattc
    11881 tagttctgtt tgggaataac ccgtcagcca acaaatgatt tcatctactt cctcttttat
    11941 acgatctttt ctctccgctt ttgctacata cataggataa acgcttgcaa aacttgtcgt
    12001 aaaaatacga ttttgcgcca taatcagtca cctttctttt tttcaaatta tttactactt
    12061 atagtatata agaaaaagag aagaaaaagc gattattcaa aaaaacaaaa aggattgtga
    12121 caaaattctt gtcaccatcc ttttttccgc tctctgactt tttacaatct tcatagctca
    12181 agtgcgcatc agataatcga atgctcctaa agctgcagta gctcctgaac ccattgaaac
    12241 aatgatttgt ttgtatggac tatctgtaca atcaccagct gcgaaaacgc cggggatatt
    12301 cgttgcgcca tttttctcgg tcactatttc atttcttgga ttcatttcga tcgttccatc
    12361 tagccaatcc gtattaggga gtaagccgac tagaatgaat actcctgaaa cagctagtgt
    12421 atgcatctcc atcgtacggc gatcgatata ggagagagat tctacctgat tcgtaccgct
    12481 gatttctttc gtcgctgcat gtttgataac agtgacattc gcaagagaga ctagtttatc
    12541 ctgtaagatt tgatctgctt ttaattctgg taagaattct agaacatata catgttttgc
    12601 taacccagcc aaatcgattg ctgcttcaac accagaatta ccaccaccga taacagcaat
    12661 ctcttttcct ttaaataaag ggccgtcaca gtgtgggcaa taagcaattc ctttattttt
    12721 aaactctttt tcgcctggta cattgataga acgccagtgc gcacctgtcg cgatgatggc
    12781 ggtttttgct ttaagtgata taccgttagc taagccaata ttaataaaat gttgctcttt
    12841 atttaaggaa acggcctgtt gattcatcat aatgtcgata gggtaactac gcacatgact
    12901 ttctacttgc tgcatcaatt ttggaccttc tgtgtaagag gtaccaatca tattttcaat
    12961 ccctagtgtt tcaacgactt gtccgccgaa agaatcagcg acaagtcctg tacggattcc
    13021 tttacgtgct gcatagatag ctgcactact agctgctggt ccaccgccaa tcactaatac
    13081 atcataaggt tctttttcaa acaactcttc ttcaatcaaa gggccagtga ttttttcaac
    13141 aatttgttcg atcgtcatgc gtccgctact aaattcttct ccatttaaaa acacagttgg
    13201 cactgccatg atttttttat catcgatttc tttttggaac atcccacctt caatcatcgt
    13261 atgagtaata tttggattta atacagctaa tatattcaat gcctgtacaa cgtcggggca
    13321 attatgacaa gtcaagctaa cataactgtc aaaatgcaat gtttgtgtta tttttttgat
    13381 tttaagactc aaagattcac tgattttcgg tgcccgtcca ctaatttgta acatagccag
    13441 taaaaaagag gaaaattcat gaccgagggg gataccagca aaaacgattc cactttcttt
    13501 gccaactgga ttgatagaaa aactaggtgt gcgcatcgaa tctctttttt cccaagagat
    13561 tttaggagac atttctgcta tttccttcgt aaattcagct agtttttgac tattttcact
    13621 attatccaaa ctaacagaaa aaacaatagg agattcaatc agtgctaaat attgttcgag
    13681 attttgttta gtttctttgt ctaacatatc caccacctaa atctttccaa caagatcaaa
    13741 acttggtttc aatgtttcgc cactttcttt ccattttgcc ggacaaactt cacctgggtg
    13801 ggtacgtaca tattgagcag cgcgaatctt atcaatcagt gcactagcgt cacgaccgat
    13861 tccatctgca ttgatttcca tagcttgaac gattccgtct ggatcaataa taaatgttcc
    13921 tcgctgagct aatccttgct cttcatccaa aacatcaaaa atacgagaaa tctgatgaga
    13981 cggatcaccg atcatcacgt attcgatttt accgatagca tctgatgtat catgccatgc
    14041 tttgtgagta aagtgggtat cggtagagca agaaaagact tcaacaccta aagatttcaa
    14101 tgtactgtat tgttcttgta agtcttctaa ttcagtagga caaacaaaag taaaatcagc
    14161 tggatagaag caaagaatac tccagttccc cataagatct ttttcactga cttctaaaaa
    14221 ttctccttga tgataagcat gtgcattaaa ttcttcgatt tttttcccaa tcaatgacat
    14281 agtaaaacct ccaataataa ttatttattt ataattattg taatttagtt ggagttgcaa
    14341 agtcaatgga tattttgtta tttaataaag attactcaaa aacgaaggtt aattataaaa
    14401 atagaagagg tcgcaagaaa atgctactgc tggaaatact cgggataacg ttgagtaaca
    14461 gtttcctgtt ctttcagcat catgtgtaag tgcaatcccg tttgaaatcg agcttcttct
    14521 ggttttttat caactaaagc cttgagtaaa tcataatgtt gttccatgat cgtttcccat
    14581 ggaagcccct gaatggtcac tcgtaaccag cggaaacgtt ctaaatgggt attatggtca
    14641 tctaaccagt tccaaacttc ttttcttcct gcaatttcga aacaagcttc atgaaataaa
    14701 ttatctgcac ggaaaaaagc gcgttcgtca tttattttga ctgctttttc ttgttcttct
    14761 aaaatcgttt ctagcactat tcgtgtttgt gtgtccaatt tggaacaaca ttcaatcatg
    14821 atttgctctt ccaactgttc tcggacaaag cgagcatttt ctgcagaaac aagattaatt
    14881 ttggaaacat acgtaccact ttgaggtatc gtatacacga gttcttgctg acgtagttga
    14941 atcaatgctt cgcgaatggg agtccggccg atagcaagat gttcctccag tgccttttca
    15001 gatattttcc ttccaggttc taagtcagca tagataattt gtttacgaat cgcttgataa
    15061 gcttgtgatt gcaagctgct tttcatcttt attcctccaa aatcatttct atgaacgtag
    15121 tataacagaa gaggtctgaa aaacaatctg gtatgtcaca ttaactagta aatttgtata
    15181 aatagtaaaa ttttggttga catagcgatt tttattgcat aaaattcact tgaatacaaa
    15241 aactaatatg ttagtttagg aggggaaaaa tgattgattt aaacaactgg aggaacttta
    15301 tccctgaatt atctcaaaaa gaagtagaaa tacctcattt tgaccgtgca tcattaagag
    15361 aaaatggaca aaaaaatcct gtctggatcc atttcggtgg cggaaatctt tatcgaggat
    15421 ttcatgcaga aatcgctcaa cgtttagcgg atctaggcga attgtccact ggtgtcattg
    15481 tttgtgaaac attcgatgaa gaaataattg aaagggctta ccaagatttt gatgatttga
    15541 ttcttgaagt ggtcatgcca agcagtggag agttcgtcaa acgtatatta gctgcgacag
    15601 ctgacagtct gtattgtcat ccagattgtt ctgaacactt tgataagatg attcgacact
    15661 ttgaaaatcc tagtttacaa ttagttactt ttgctattac tgaaaaaggt tatcgattga
    15721 aagatacaaa taataaatat ataggaccga ttgcagtcga tataaaaaat ggtccaaaga
    15781 agccatcaca tacaatgagt attcttgctg tgctacttta taaacgtttt ttatctggag
    15841 cttggccgat tgcacttgtc tctacagata atttttcaca aaacggtagt caattacgta
    15901 cttctttgct aacgatcgca aaagaatggc aaaaggaagg ttatgtacaa aatacattta
    15961 tccaatactt atcgaatgaa gaaattgttg cgtttccatg gacgatgatt gatcgtatca
    16021 ccccgaatcc ttccttgtca gttagcaaaa tgttggcaaa agagggcttt tcaaatatgt
    16081 cgattttcca aaccgcaaaa ggaaataata ttgctccatt tgtcaataca gaggacatcc
    16141 attatttaat catggaagat cattttccca atggacgtcc gaaattcgaa aaagctgggg
    16201 tattcttgac tgatcgtgca acggtagata aagcagatac gatgaaggtg acgacttgcc
    16261 ttaatccttt gcatacgtct ttagctatta tgggttgttt actggggtat aggagcatag
    16321 ctgaggagat gaaagatcca gatttatcgc tgctagtttc tgaaatcggg tacaatgaag
    16381 gcctcccagt tgtggagtct ccaggtatca ttgatccaaa gatctttctg gaagaagtaa
    16441 ttactgtgcg cttttctaat ccaaatattc ctaatatgcc tcagcgaatc gccacggata
    16501 cctctcaaaa ggtggcgatt cgttatggtg agacgattaa aaaatatatg gaaatagaag
    16561 ttaaagaccc gcagacactt gtattcatac cattgactct cgctgcttgg cttcgatacc
    16621 ttattggcat tgatgatcaa ggaaaaccat tcatcccgag tccagaccca ctattgacag
    16681 accttcagca taagctttcc gatattcaac tgggtacgca agatacatca catattcatg
    16741 agaaaatggc tcctattttg tcaaataaag aaatttttgg tgtagatctt taccaagcag
    16801 agcttggcag aaaaatagaa gaaatgttca tcaagatggt agcaggacca aatgccgtac
    16861 gaaaaacatt acaggattac ttacaagaac atggaggaaa tttatcatgg aaatgacttt
    16921 tagatggtac ggatcacagg aagaaaagat taccttagat gaaatcagac agattcctgc
    16981 ggtcaaaggg attgtaggca cattgatgga tataccagta ggagaggtat ggcctaggga
    17041 gaggatcaaa gaactaaaag aagaaattga gtctcgtggg ttaacactaa aagtaattga
    17101 aagcgtcaat gtgcatgatg ccattaaaat tggattacct tcccgtgagc agtatatcga
    17161 aaactataag cagacaatcc gaaacttggc agaatatgga atagaagtca tctgctataa
    17221 ttttatgcct gtatttgact gggtgaaatc tgaccttgac taccgcttag aagacggctc
    17281 atccacgtta gcttttatat ctgatgatat tccagatgat ccaagagaaa tcgtcgcgcg
    17341 catcgaacat tccagcaatg aatttggatt gccgggatgg gaacctgagc gcttagctcc
    17401 tatcaaatcc ttgcttgaag cctatgcatc agtagacgaa gaaaaacttc gagaaaattt
    17461 tgcctatttt ctccaatcaa tcatcccaac atgtgaagag gtaggggtca aaatggctgt
    17521 acatccagat gatccgccat actcgatttt tggattagct cgaatcgtaa agaatcgaga
    17581 agatttagat tggttgtgtc gcatagtaga cagcccttat aacggaatca ctctttgtac
    17641 agggagtatt gcagaagatc cagaaaatga tgtatatggg attttagcag aattttgcca
    17701 aagagatcga atcccatttg cacatgttcg aaatattaaa tttttagcta atcgagattt
    17761 ctatgaggca ccacataaat ccgaatacgg ttcattagac atgtaccgca tactaaaaac
    17821 aatgtatgac aacggattta acggatacat ccgtcctgat catggaagaa tgatctggaa
    17881 tgagacagga agaccaggat acggcttata tgatcgagca ttaggtgctg tttatctaaa
    17941 tggattatgg gaagcaatcg aaaaaggaaa caaaagtaaa gataattagt gaaaaaaact
    18001 gtaattttat tatgtaaata agaaggatgt tcaaattctt gatacataaa tccggaggtt
    18061 gttaataagc attcggattt atgtatctta tttggtctag gaagtaactt gattttcttt
    18121 tttcgattga tccatgagtg cttcttcttt taattcaaag atatattctg agatcctcat
    18181 aatcactttt ttccagtctt ctggtgtgat gattcctttt aaaatataga tttttttgat
    18241 atgagaaggc aattgtttca aagggcagtc gctgataacg atgttgcagt tctccataaa
    18301 atcattttgt attttgatcg attcatttga aaaaatttgt tctatcttaa cgatcagatc
    18361 tttactgata taaaaatcac gcgtatagtt cacaccaatc acaattcgcg gctgtttttt
    18421 gtagcgatca tacaaatgta ctaggtcttc aaccatccat tgcacatttt ccttttctaa
    18481 aataactggt aacaagtgtt gattttgttc tctgaaatcc atataaaatt gttcaatggc
    18541 ggtttggact tctttcaata cgctatgttc ttgataaagc atgaaagtag gaaggggcgt
    18601 atttggttga ttgaagttaa gaaatccatt ataaagttta tttcgtgcga atgccaatga
    18661 gtaaagaatc ttttcttttt caggtataaa caaatcaaat acagtacaaa gggactccac
    18721 catttctctt gaataaagaa catgaggaac gtttgctttt tttaaaagtt tgtattgctc
    18781 caagcttgtt tcttccgatt cgattttcgt gatagaaagt cgagctaaaa tattcactaa
    18841 gatgcgttgt tcgcgacaaa ttggcagatt aggtcgcaaa atatctacag agagatcaat
    18901 aaaaaagtca atatattcat actctgtgaa ttctttttgt acgtctttca cagaagttgc
    18961 aggaaaattc tctttacata tttttaatag aaaatataat ttatctatca taccgctatt
    19021 tagtcggtca agtacttctt ttttaaaaaa agtattcatc ataaaagcca ctacttgcgg
    19081 atcttcatca taaaattctg tagcagtact tgaaaagatg ttccaataaa tatctaatgc
    19141 tgcatattga atttgtacct cttttccaga aaaagacttt ctgccattat tagaaaagga
    19201 gatagacaaa ccgtactatg ctaaaaatgc attaatcttt ttcattttcg tatacaaata
    19261 agaggcacta tagtttgttt gctgactgaa actgataatc gaatttgtct gacagctgaa
    19321 caaagaagtc aagatctgat aactgactga ttcgttgcag tatcttccaa atagacgata
    19381 atagcagtaa gccggatcaa ttccttcaaa attcaacttt aaaaaaggtt tttgcttatc
    19441 aatatgcagt tctgttagat tgagacgctc aaagtcttgt tctaattctt tgatgtatag
    19501 taaaaaattt gattcagaca tatggaaatg atctgctaaa tattgtgtag taataaagaa
    19561 acgatgttca gataggaaaa gaaaaatatc taattttgta ttgctttttt tcttcaagat
    19621 aaacgtttta atcgcttctt gagtttgcat gaaagaggct cctttttact taaattgtta
    19681 aaacttgaaa atattactgt ttttttcata aatttagaca aaaaaacagt aaacatatag
    19741 gtagaatctc tactatctta tttcttgcat acaaaaaaat caaggagtga gagagttatg
    19801 agatattcaa ccatcttaat atcaacattt gcagccttaa gcttatcgct tactataaat
    19861 cagacagtcc acacagagga gacagaaaca gccaaatgga cagaaaccaa gtgggccaac
    19921 gtcaatcgaa ttacctttca ggatgaattt tcatccttca attcaggagt cgcaaaatta
    19981 agaaaaggac aaacagcgac catcaaagca aaaattgact attcgggaga cttagcacct
    20041 atactacaat cagctgttac atttgagaat gttgatccca ctttgtcgat tggctatgac
    20101 gagaacactt tgactatcca acacaagcaa gcgatattta ccttcaccgt tacattaaat
    20161 caggacttgt taaaaccagc gctttttact gtcaaggtat cagatggact accgaacgat
    20221 catcatttaa cgccgtatag tcagcggcag acaattgagc aagattcagc catcgactca
    20281 ggaggagatc ttgttgaaga accaacagat aaaccagaaa atgaaaataa gccagaagta
    20341 ccgcctacag aaaatccaga cggagaacag aaaccggaaa tagaacctgg agaagaaccc
    20401 gatacagaaa ctcaaccaga gccagacaat aaatcaaaac ctgaaataac ccctggagaa
    20461 aaaccagatg taactccaga accagatacg gattctggaa accaaacagt accggaaaca
    20521 aatccagaca cagataatga aactgaaaat ccagaaaaac cagaggtaga tccagaagaa
    20581 aaaccagatg tgactccaga accagatacg gacgcaagag accaaggaat accagaaaaa
    20641 ataaacaaaa aaacaattca agaggatgga aaaaaagaga gtaaaaaatc aaatctagca
    20701 attctaaaaa taaatgaaga gcagctgaat aaaaaatcac gaatatttga tagcgcccaa
    20761 tcagctgaaa ccttaaaaag tagcaaggat acaacctttg ctgtcctgaa acgaaaaata
    20821 aacagctacc aaaatccgga gagtcacaaa acaaagttat actgtggagc ggaatcattc
    20881 tattaagtat agcaacaatg ctttctgcaa aaagatttaa acaaaacaga tctctctaac
    20941 atttgaataa tgtctgtgaa cgcatttttc aaataaaaag aaatatccag aaaatgaccc
    21001 caaaatacca gattgaaatc tgatatttgg ggtcgttcat actttatctt tcttcatatt
    21061 tattttaagg gatatctgtt tcttttggaa gatggttcgg gatctttttc actttcaata
    21121 catctaaaaa gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg ccaaagaacc
    21181 gttcgctaac aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt ttgctggaca
    21241 tcaacttcgg attcagcaca taagactcaa ttagatggac aatcaaaatc gtaatcagga
    21301 tataaacaac atctcggatg cctccttggg aataagctat gaaagataga ggaatacaag
    21361 aaatgataac acctgctact gggatcagac ttaaaatgaa aatcatgatc gctaaactca
    21421 gcagctgatg aaagccaaat acagccaagg cgattgtagt gagcaacgta tttaaaagag
    21481 cgacaacaaa ttgagcttct aataccaaac caaatgtatt gacaaactta tcggcaaaat
    21541 agtaaatatc ttgaaagaac caagaaaatt cactttttaa aaacaatctt gagaatacaa
    21601 ttgttttttt cttttcaatc ataaaaaaga aacttaagat gaatgacata gcaaacgcca
    21661 ctgccatttt tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca ttttgaagct
    21721 gttcaaaaaa atcgtttcgc tcaatataag tatggatata ttgtaaaaca ggatctgcat
    21781 cttttggctg atgctcgtaa aaattaataa cggactggat catgtcaaat gtttgatgaa
    21841 taagcatcgg gatatacttt gtgaatgcca gatagataag gtaaacgatc agtgtataaa
    21901 tcatgatagc taaaacacct gtagggattc ggacaaatcg ctgaatgatt tgaacaagat
    21961 gaatcatcaa ataagtaaag ataaatgtga gcaaaatggt tgtaatcata cttctaacta
    22021 agaaaagaac aaaaacgaca aataataaaa cagtgagacg gcgtattttt tcattcgcca
    22081 aaaaacgctg ataaacggtc aaatcgacaa cctccaaata acaaaaaata aacacgttat
    22141 tcattatatg atggaatatg aaaataagaa agagcaaaaa gaaaaaccgc taaatgacgt
    22201 tatcttatga gttggttttc ctcataaaat cgttcatcta gcagtttcag ccctttttct
    22261 ggtcttgatg aaaattatct agcatttttc gggtcagatg ttgcagtgta tccaattctt
    22321 cctgttcaag tggaagataa gacttgatct tttgtggaat accttctgct tgtttttgca
    22381 acgcagcacc ttgagcagtc agcgtaacat ttacgattct ttcatcaccc gtttcacgct
    22441 gacgattaat ataatttttt tctgctaact tttttagtaa gggagtcagc gtaccagaat
    22501 ccagacacaa atcatttcct agctctttca ctgaagtctt tttcttttcc cataaaacta
    22561 acatcacaag atactgggta taggtaagat tcagcggctt gaggagggga gtgtagtgtc
    22621 taatgatttc tttagaggcg gcatataaag gaaaacatac ttgattaact aaatatagat
    22681 cttccatttt tccacctccg ctgttttact atagtgtatc atagcggatt tacacaaaaa
    22741 agtctattca ctaactgctt tcagagtaac ttctatattt ccagctgtag cttttgaata
    22801 cggacacact ttatgcgctg cctctaataa ttcttgcgtt tcttccagag aaagaccttc
    22861 gatagatcct tcaatctcta cacctaagac aaagctcgtt tcactttctg aataaaggga
    22921 aacttgtgca ctgacagtag aagccccaga gatatttttt tgctgtttga tcaattctaa
    22981 tgcactgtta aaacatgcac tgaaaccagc tgcaaacaat tgttcagggt tggttgcatt
    23041 ttcgacgcgt ttaccaggag ctgcaatatt caattcgaat gtacgatcgg gattatgcac
    23101 ttctccagag cgtccgcctg tgttgatcat tttcgtagaa tacatttttt tcataaaatt
    23161 accaccttta attatatttt atacaattga attttacaca atataattgt ggaaagcaaa
    23221 gaaatggatt ggcataagat aaataagaga aagcacatga aacagacgcg ctttctcgaa
    23281 tagcaaacat atacaaaaaa tatcagagac aaaaaataat ctcatcataa acattacata
    23341 tatttctcaa aaagttgttt tctttcttca aaaattactt cacgatggac ctgatgaagc
    23401 atccataaat aaccaaaagg atctctgaac attgagttag tcacaccaaa gtccatcatt
    23461 tctgtcattt cttgaatctc tacacagcca tttcgtaatg ctttattatg tgtgtcctcg
    23521 atatcagaga cgatgatatt gaaccagatc gtatttggat gttcagcagt aggagcagtc
    23581 aaaccaagag acgtgttttc atccagcata tggaatctcg taccatacaa ggtaaaaatg
    23641 acttcattat tgcctctagg gtaatctgtt gcctcaatca gttgtatttc atcaaagatt
    23701 gtttgataca gttctagtgc tttcaaacta tcatttaata caaaatcgat ttccgttcct
    23761 ttatgcataa agatctcctc tccttttcag tcgaacagtt actagattct tttattatac
    23821 cagctaaaga aaacgcattc aaaaaaatag cggatttact taccaactca ttcgattgga
    23881 tgataagtaa atccgcgtcc cattacttct gctacgctgc tgacaatgac aaaggcactt
    23941 ggatcgattt cttctatcaa tggtttcatt cgggaaaatt catgatcagt cacaacgatc
    24001 aataaaacct cttttgactt tcgattatac ccgccttttg cctctagcag ggtaaggcca
    24061 cgtccaatct cagcacttaa gcgaaggcgg atgtcttcca aataatgttc actcatgacc
    24121 ataacagatt tctttcgatt gatacctgtt tcgatataag tcatgacaat tgaagtgatt
    24181 gcaatagata aaatagcata aagaaactct tctattccaa aaataaacag attaagagaa
    24241 acaacgaatg cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa atatttttta
    24301 aaaatgaggg gagggatcgt cgtaccgccg ctagaagagt tgtttttata taaaatcgca
    24361 actcctaaag caaaaatcgc acttccaaaa atgacagaca acaaccgatc tgaagtaatc
    24421 attgtttctg gaactattgc aatgattaaa ggaaaaacca agcttccgaa aagtacttta
    24481 aaaaagggtt ttttacctaa aaatagaaga gctagtacca acataacgat attcaacact
    24541 aaaataacta tagctcggtc aaagcctaaa gcagcttcca gtaatattcc tagaccgctg
    24601 acacctccag cagcaatatg atgaggccct aaaaacatat tgatagcgac tcctaatatg
    24661 aagagggcaa aaataatctt aatgtatgtc catataaatt gtctcgtttc tttcatttat
    24721 tcacttcctt aattcattaa taatactctt atcttattat aacttacttt tcaccttaag
    24781 ttaactttaa ttaataaaaa aattaggcta gtctaaatta ttatgtttca ttcttctaga
    24841 atatacttct acgccaaaaa ctgttaaaaa acttttactt tagaaaattg gagaaattga
    24901 tcgcttaaga taaattcagg acactaaata gtacaggaag tagactaaaa cttttaaaag
    24961 ttttaagtct atctatttgg caagtttaaa aaataaaaat tcggtatcaa aaaactgtta
    25021 ccgataacat ttttgaaagc gttgtctttt gcttctctat cacttatagt gatgacgtca
    25081 tattaaaaca caaggaggaa atcaatggat acagctgcaa tttatcatcg accggaaagt
    25141 gaatatgcat ttctatatac gaatacaaga tttcgtattc ggcttcgtac taggaaaaat
    25201 gatatcaaaa aagtatatgt gctatgtgga gatccatata ccataacaac tgaaaaatgg
    25261 tatcaaaaac aacgaccaat gaaaaaatgt ctaagtacca atgttcatga ttattgggaa
    25321 attgaagtga cgagcgaaac aagtcgctta cagtatgcgt tccatgttgt tggggaagat
    25381 aacacggact gtttttacgg tgatcaagga atttttcctt atcgagaaaa tgtgattact
    25441 gaaccaaatt tttattttcg aataccttat tttcatcaaa tcgatcgatt cactattcca
    25501 gaatgggtaa aagaaacagt atggtatcaa atttttcccg aaagatttgc aaacggggac
    25561 aaagcaaatg accccgaaca cactttacct tggggaagta aagatccaga ccgagaagac
    25621 tttttcgggg gagatttgca aggtgtgatg gatcatttgg attacttgac ggaccttggc
    25681 atcaatggca tctatttttg tcccatattt aaagccacat ccaatcataa atacgatacg
    25741 attgattatt atgaggtgga tcccgctttt ggcgataaaa aacttttaaa aaacttgatt
    25801 gatgaagcac ataaaagagg gatacgtatc atgttcgatg ctgtattcaa tcatatgggt
    25861 gtccattcac cacagtggca agacgttctc aaaaacggag aaaaatcgat ctataaagac
    25921 tggttccaca tccgtttttt cccagtagat tcttatcaga tgactgactt accagaaact
    25981 gctgaaaata tcccatatga tacttttgct tttactccat tcatgccgaa actaaataca
    26041 gcaaatccag aagtgcaaaa atatttgctg gatatcgcaa cttattggat aaaagaattc
    26101 gatattgatg gatggcgtct tgatgttgct aatgaagtcg atcatcattt ttggaaaaaa
    26161 ttcagagaag cagttacaga aatcaaacca gacatctata tccttggaga gatttggcat
    26221 tcctctcaag cttggctgca aggggatgaa ttccatgcag tgatgaatta tgcatttaca
    26281 gattcgatta aagattattt tgcaaaaaag aaaatcacag cttcacaaat ggtcagtgga
    26341 atgaatcatc agcaaatgct ttacagagat caggtgaacg aaggaacatt caacttatta
    26401 gattctcatg atactgccag gatcttgacc ctttgccaag gtaacaaaga attgatgaag
    26461 tctgtgatgg cctttatgtt tcttcaaaaa gggtctcctt gtatctatta cgggacagaa
    26521 atagggatga ctggtgaaga tgacccggat tgccgcaaat gtatgatatg ggagaaggag
    26581 gaacaagatc tagagctatt cggttttata aaagaacttg tttctctaag gaaacagttg
    26641 tctaagatta tttctgaagg ttctactcag tggctaatag taaatgatcg tgaagataag
    26701 ctctatttca cacggaaact agagggacag atcatctatg tttactttaa tcagtcaaaa
    26761 gaaccttggg tagtagaaca ggaaaatgag gtgattctta gtcaaaattg tcagttgtta
    26821 gaagacggga aagcagagat acgacaatac ggatttttga tcatgtgttg aaaactgtta
    26881 ccggtaacaa caagaaagcg tttgcaaatg aagatttgtg cccattataa taagggtgta
    26941 acagcacgtt gaatacaaag gaggaaatga agatgaaaaa aagaagtgtg aaacagttgg
    27001 gtttagggtt aatctcttta ggaatcttag gcggattagc ggcttgtggc aatggtaact
    27061 cttcagcaga aggggaagcc gatgaaggaa aaacgttaac agtttccgtt gattctggat
    27121 ataaagatta tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat gtgaaaatca
    27181 agctagtaga aaaggacatg ttcgatcagt tggaatcatt agcgttagat gggcctgctg
    27241 gaaagggacc tgacgttatg atggcagcat atgaccggat cggtgcgtta ggacagcaag
    27301 gacatctggc ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca gacaaagccc
    27361 aagtgactta tgatggaaaa atctacggag aacctgcagt aatcgagacc cttgttttgt
    27421 actataacaa agatttagtc gatacagcac catcaacgtt taaagatttg gagaatctat
    27481 ccaaagacag tcgttttgct tttgagtcag aagcaggaaa aaatacagga tttttagcta
    27541 aatggactga cttttattat tcctatggtt taattgcagg ttacggtggc tatgtatttg
    27601 gtgatgatgg cacaaatcct tcagatatcg gtttgaataa tgcaggtgct gtagaaggaa
    27661 tctcttatgc aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa gacataaaaa
    27721 gtgcaggaga cttcgccagc cagcaattca tgtccaataa aactgcagca atcattgacg
    27781 gtccatggca agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta gccaaaattc
    27841 ctactctaaa taatggacag ccttatcaac cgtttggcgg aggaaaagga tgggtagtca
    27901 gcaattatgc taaaaacaaa gacctctctc aaaaatggct tgattatgta acgaatcagg
    27961 aaaatcaaga aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa caagctaggg
    28021 aaacagcaaa ggctaaaaac gatgaattaa caacagctgt gattgaacaa tatgaaacag
    28081 ctcaagcgat gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca gaaaacttga
    28141 tgttcgatgc agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa gcagtaaaaa
    28201 caatcagtga agccatagaa caaaaatact gattaaaatg ataaccgtcc atttttataa
    28261 aaaatggaac aggtgcttca gataaaagtg gcaagagcga gatggaaaat tatcttgctc
    28321 ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg gcattcagat
    28381 gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt cacttattcc
    28441 agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt tcgccatatt
    28501 cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag gattggttac
    28561 tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag gcactttgca
    28621 attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag acgcttatcg
    28681 agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg aagtcataca
    28741 taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc ttctcatgat
    28801 ttttacgatc attttcccag tcctagttac attgttcact gcatttacta attatgactt
    28861 caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact tttttagtat
    28921 cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga ccgtgatttg
    28981 gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg ttgttgctca
    29041 ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac catgggcggt
    29101 cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg taggtgccat
    29161 caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca gtgcaatctc
    29221 ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg gctggttagg
    29281 atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag aagacttata
    29341 tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca tcacgcttcc
    29401 tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga atttcaataa
    29461 tttctccatg atctatctgt ttaacaatgg cggtcccgga agcgtaggcg gaggagctgg
    29521 ttctactgat attcttattt cctggatcta taaacttacg actggaactt ctccgcagta
    29581 ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg tgtcattgct
    29641 ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa atttcattcg
    29701 agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct tttaatactg
    29761 tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa gtcaggaaat
    29821 attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt tactcggcta
    29881 ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc tgtcctaaca
    29941 atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg ctatcgtttt
    30001 atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc gactatggca
    30061 gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa gtactggttc
    30121 ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat gaaaggatac
    30181 tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc agggcatttc
    30241 aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt tcaagcatta
    30301 tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct tcgaacacct
    30361 gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac aaaccaaaga
    30421 gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct attattcttc
    30481 tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg ataggagcag
    30541 agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc aactcaagtg
    30601 tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt atttttagtt
    30661 tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc gattccatta
    30721 gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa attttctgaa
    30781 cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt gacccctgaa
    30841 attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac ttttattgat
    30901 tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg ccgctatacg
    30961 atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga tttccaacga
    31021 tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc ttatagttta
    31081 agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc ttcctttttc
    31141 ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga gagtgcaaat
    31201 ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg gtttatccac
    31261 tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct gcttttatgg
    31321 gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta agcgatttat
    31381 gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt tctgaaaaaa
    31441 ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt agttttttta
    31501 aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg ttctttctcg
    31561 ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga tacggacact
    31621 cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat tacaagtaac
    31681 gcatctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga gggaagtatc
    31741 caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg aaaagattat
    31801 ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga agatatccat
    31861 gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac tttgacttat
    31921 tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat caataaagtc
    31981 catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga tatcggttgt
    32041 ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc aactgggatc
    32101 acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga acatttagaa
    32161 gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac gtttgatcat
    32221 atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg ttatttcaaa
    32281 gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat cagccgacaa
    32341 caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg ttatgtccct
    32401 ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat tgatttggaa
    32461 agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt tcatcaagtc
    32521 caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga tctatattta
    32581 caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata tttgcttgtt
    32641 caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa gtactgttta
    32701 aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt ttttgtctaa
    32761 cttctaggat tgtctctaaa gcttagtttc
//
LOCUS       DASHWW010000023        31679 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.023, whole genome shotgun sequence.
ACCESSION   DASHWW010000023 DASHWW010000000
VERSION     DASHWW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.023"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..680)
                     /locus_tag="U2R64_001269"
     CDS             complement(<1..680)
                     /locus_tag="U2R64_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8918098.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELR"
     gene            complement(746..2035)
                     /locus_tag="U2R64_001270"
     CDS             complement(746..2035)
                     /locus_tag="U2R64_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEM8918099.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(2122..2826)
                     /locus_tag="U2R64_001271"
     CDS             complement(2122..2826)
                     /locus_tag="U2R64_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEM8918100.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            3026..3292
                     /locus_tag="U2R64_001272"
     CDS             3026..3292
                     /locus_tag="U2R64_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918101.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            3305..3463
                     /locus_tag="U2R64_001273"
     CDS             3305..3463
                     /locus_tag="U2R64_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918102.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(3460..3690)
                     /locus_tag="U2R64_001274"
     CDS             complement(3460..3690)
                     /locus_tag="U2R64_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEM8918103.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            3762..3917
                     /locus_tag="U2R64_001275"
     CDS             3762..3917
                     /locus_tag="U2R64_001275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918104.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            4074..4229
                     /locus_tag="U2R64_001276"
     CDS             4074..4229
                     /locus_tag="U2R64_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918105.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(4226..4450)
                     /locus_tag="U2R64_001277"
     CDS             complement(4226..4450)
                     /locus_tag="U2R64_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEM8918106.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            4717..5052
                     /locus_tag="U2R64_001278"
     CDS             4717..5052
                     /locus_tag="U2R64_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918107.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            5285..6226
                     /locus_tag="U2R64_001279"
     CDS             5285..6226
                     /locus_tag="U2R64_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HEM8918108.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            6228..7118
                     /locus_tag="U2R64_001280"
     CDS             6228..7118
                     /locus_tag="U2R64_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEM8918109.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            7161..7961
                     /locus_tag="U2R64_001281"
     CDS             7161..7961
                     /locus_tag="U2R64_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEM8918110.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            7976..8827
                     /locus_tag="U2R64_001282"
     CDS             7976..8827
                     /locus_tag="U2R64_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8918111.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            8824..9141
                     /locus_tag="U2R64_001283"
     CDS             8824..9141
                     /locus_tag="U2R64_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918112.1"
                     /translation="MNLTKQEKRICRQIMLQIIGDRDMDELSQQESRMVRKISKLIGA
                     DTMDRSKPLPKLNFESFTFEKYSHLREVGYSVNAIRKALGVGSSVWAKWRKENVNEVN
                     QND"
     gene            9134..9316
                     /locus_tag="U2R64_001284"
     CDS             9134..9316
                     /locus_tag="U2R64_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918113.1"
                     /translation="MIKLIGKETLKVYYVAETKAEVSRWLLKMFNKTRANASVSQKAS
                     VSETGMPEAMWISRRN"
     gene            9318..9788
                     /locus_tag="U2R64_001285"
     CDS             9318..9788
                     /locus_tag="U2R64_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918114.1"
                     /translation="MAMIPKFRAWDREKDRMIYPSTTGVCFEMNDDGISVLDIDVDYP
                     NDYGFPKIASILMQSTTLKDKNGVEIFEGDIALITHKSTNYADTYWHSYVEVFRAKNG
                     AYRIRGEHIYETELYSNRKQLTVAGNVYNSPELLKRDRFMTTTENPELLKEEQR"
     gene            9785..10327
                     /locus_tag="U2R64_001286"
     CDS             9785..10327
                     /locus_tag="U2R64_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEM8918115.1"
                     /translation="MNKQELIDKYTAEISRLRPYCPNRHLISDQLKYGLYKEILEDLK
                     QLDEPQKPAVPKFVAEWIEYAKKKGDSLAISFKPWNLYGVEYSKTDRWIEDNQGTFAR
                     AWLIGYEVEKEPLYYVKLPVVYFNHWDLETYLMKDDRGNITIADNNDFDDMKFTESEI
                     KAIDERYWPFAVPVEEVAEG"
     gene            10324..10707
                     /locus_tag="U2R64_001287"
     CDS             10324..10707
                     /locus_tag="U2R64_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918116.1"
                     /translation="MSNLKVGDIVFYKGDEGIIREVMTDGKENFYRVDVSRKSILYLY
                     EDELDLGTQKLNDNQKMVFDYLKSNVEQGGKSVMYSIFLLGDWDSRIGAARNVDIDYC
                     GLNGKQEAEVLSAFAQWGLEQEEAE"
     gene            10704..10934
                     /locus_tag="U2R64_001288"
     CDS             10704..10934
                     /locus_tag="U2R64_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918117.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            10941..11144
                     /locus_tag="U2R64_001289"
     CDS             10941..11144
                     /locus_tag="U2R64_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HEM8918118.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            11141..11437
                     /locus_tag="U2R64_001290"
     CDS             11141..11437
                     /locus_tag="U2R64_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918119.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDIELINDK"
     gene            11514..11927
                     /locus_tag="U2R64_001291"
     CDS             11514..11927
                     /locus_tag="U2R64_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEM8918120.1"
                     /translation="MQLLREVAFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            11940..12326
                     /locus_tag="U2R64_001292"
     CDS             11940..12326
                     /locus_tag="U2R64_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918121.1"
                     /translation="MWKDYVSLKELKKDLIFKKIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHSSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKEKLCVVTDA"
     gene            12818..12890
                     /locus_tag="U2R64_001293"
     tRNA            12818..12890
                     /locus_tag="U2R64_001293"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12851..12853,aa:Lys,seq:ttt)
     gene            13276..13536
                     /locus_tag="U2R64_001294"
     CDS             13276..13536
                     /locus_tag="U2R64_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918122.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSVFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            13579..13752
                     /locus_tag="U2R64_001295"
     CDS             13579..13752
                     /locus_tag="U2R64_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918123.1"
                     /translation="MKQYTAKDFEEMKRLKKDYEEVDMELTVGVIQRRLRVGLETAKA
                     IYNDLNAIEEKNG"
     gene            14141..14974
                     /locus_tag="U2R64_001296"
     CDS             14141..14974
                     /locus_tag="U2R64_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HEM8918124.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFETLSDEEKDIYSSLNDNPSFVLSEEIRLLKIRQFRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKNPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            14967..16382
                     /locus_tag="U2R64_001297"
     CDS             14967..16382
                     /locus_tag="U2R64_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEM8918125.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            16394..17923
                     /locus_tag="U2R64_001298"
     CDS             16394..17923
                     /locus_tag="U2R64_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8918126.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            17841..18893
                     /locus_tag="U2R64_001299"
     CDS             17841..18893
                     /locus_tag="U2R64_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEM8918127.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            18895..19212
                     /locus_tag="U2R64_001300"
     CDS             18895..19212
                     /locus_tag="U2R64_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918128.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            19339..19962
                     /locus_tag="U2R64_001301"
     CDS             19339..19962
                     /locus_tag="U2R64_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEM8918129.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            19977..20867
                     /locus_tag="U2R64_001302"
     CDS             19977..20867
                     /locus_tag="U2R64_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HEM8918130.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLFGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQKLMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            20890..21105
                     /locus_tag="U2R64_001303"
     CDS             20890..21105
                     /locus_tag="U2R64_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918131.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            21117..21458
                     /locus_tag="U2R64_001304"
     CDS             21117..21458
                     /locus_tag="U2R64_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918132.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            21458..21829
                     /locus_tag="U2R64_001305"
     CDS             21458..21829
                     /locus_tag="U2R64_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918133.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            21822..22217
                     /locus_tag="U2R64_001306"
     CDS             21822..22217
                     /locus_tag="U2R64_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEM8918134.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            22219..22596
                     /locus_tag="U2R64_001307"
     CDS             22219..22596
                     /locus_tag="U2R64_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918135.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            22597..23205
                     /locus_tag="U2R64_001308"
     CDS             22597..23205
                     /locus_tag="U2R64_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918136.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            23205..23546
                     /locus_tag="U2R64_001309"
     CDS             23205..23546
                     /locus_tag="U2R64_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918137.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            23788..26577
                     /locus_tag="U2R64_001310"
     CDS             23788..26577
                     /locus_tag="U2R64_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEM8918138.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNEIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            26567..27307
                     /locus_tag="U2R64_001311"
     CDS             26567..27307
                     /locus_tag="U2R64_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918139.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYRNVTRKIECYYKAPSIDVVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            27304..30066
                     /locus_tag="U2R64_001312"
     CDS             27304..30066
                     /locus_tag="U2R64_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918140.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLAEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRLIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     SLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFTSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            30079..30987
                     /locus_tag="U2R64_001313"
     CDS             30079..30987
                     /locus_tag="U2R64_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HEM8918141.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            30987..31607
                     /locus_tag="U2R64_001314"
     CDS             30987..31607
                     /locus_tag="U2R64_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918142.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVITELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT        11235 a         4625 c         6497 g         9322 t
ORIGIN      
        1 tttcttaatt caccaatgta ttttttgttc gtcaacatat ttttaacact ttgataatct
       61 ctaacgattc catactgaga gcctaaataa taaacagttt ttcttaaact accactagaa
      121 agaaagtagt tgaatatatc tatcacgata ggagcatcat catttattac taatttctta
      181 ttttctatag agtagcctaa cggagttttc ccgcttacta cttcaccttg tgcaatttta
      241 tttgccataa cagctttgat gcgttctgaa tcaatttggg cttccaattc agcaaaactc
      301 attacttgtg caatgaaagt tctgccatac gctgtagttg tatcataata ttgttgagaa
      361 acagcattcc aagaaacatt gtgtttttct aaaatttctt gagtgtttaa ataatgtcgt
      421 agatttctaa accatctatc taattttgta aataaaatta gatctatttt attttctttt
      481 acatcttgta atagtttttg aaattcatca cgatttattt tttgaccaga aataccaccg
      541 tctacatatt cattaactac tttcaaatcc ttgtgttgtt cgatatattc atagagggtt
      601 tctttttgtt ctctaagact atctccatgt ttggcttgtt gttcagttga tactctcata
      661 tataatgcta ctcgtttcat gttatctcct ttcgaatgta tgttcttatc gttgtaaaag
      721 aaaagcccga aggctaatct ttttactaca catctgttaa ttctaatgat cttctgtatt
      781 gttcagcttg agctagttta gtaaaagata cagttccgtt ataattttct aaaacaactt
      841 tttcaatttc atcaagagat actttaaaga attcttttcg ttgattaact ttattgactt
      901 cgttttttct aaaatgcgaa tgtagttgat tttctaatgt tggtgcatct tctgaaaata
      961 tcattgcatg aacatcaaat tcaaaaggta cagaagcgct actaagttcc ttaattctat
     1021 ccataggttc taaccgtcta gtcattccta ttttatagac atcttcaccg aaagatccga
     1081 tattactgat gacataaaca tagccagctc tagtattaag ttctctttgc aatacatctt
     1141 ctttgacagt ttctagttct cttaatttct cttccagttc tttaatttta tcagcataga
     1201 gttctttttc aacatcagca ctagcttttt gcatgtatgc cattaactta gttatctctg
     1261 agttaaactg tcgttcttct ttatcaatgc gtttcttttc acgttctatt tcacgtctta
     1321 ccttttcttc ttcaatcatt tgttctttta ttgctttttg ctgttctttt tcatcgttaa
     1381 ctttaactat gtatgaatag ttgagttcta attcttgaag ttttaattca agtaattctt
     1441 ttttgaattc tgcttcatcg tttttaaaaa gcttgtttat tttatcaaaa gttcttataa
     1501 ttttttctct agttgaatct acgttagaaa tagtaagttt attgagaagt ccagttattt
     1561 ctgattctaa tggtataagc attttctttt taatattatt agcttctcta ttattcaaat
     1621 aagaaggaat attaattgca ccgtctaaaa taaaatcctt ttctttaatc tttaataaag
     1681 aaagtttgtt ttttatttcg gatgaagaag tttcatctat attcggaata attactgatt
     1741 tatagatagt gaccagagat gtgtcatatt tttgattaat ttcatcgtct aaccgctggc
     1801 tttcagcatt aagaatatca attttgtttt ctagcgttga caagttttta ttcaatttac
     1861 ttatgttttt ctctttttca gatataaacg tttccctagc atttaattct tgagaatatt
     1921 cctttacctt actctctaag gcagaagttt tatcttttaa ttttttagct tcagataatt
     1981 tgctactacc cataattatt aaaactattc caactaaaaa caatagtact cccattcaaa
     2041 acgcctcgct tcttttataa aataattgtc aaaatcatat aaacccttac cgaagttgac
     2101 ggctccggca tgggaatttt tttaaaatac aacttttccg ataattctaa tctgttctgg
     2161 cgatacaatt ctatcttcgt ataagtcgtt tatagaacgt aaaatgattg tttgattttc
     2221 gtaatcttta tatatctctt tacatgtaac tccgtcacca cctaattcca caatagcaat
     2281 ttccccatct tctacgtccg gttgttcttt aacgaatacg aattgtccat tcctgataac
     2341 aggttccatt gaatcgccta taataggtac tgcgaagtca gcagcacttg gaactctctc
     2401 aaattcttcc tcttcgacaa ccgtatcacc gtaagtaagt tctgttggat tggcagccga
     2461 agccgaattg tgaacagttg ggattttttc ttttttagga aaatctagga cattttcttg
     2521 tttttgttct tctaatcgat tacttgcaaa ttcataggta gcaactttat tttcgtcgtt
     2581 aagctgatta tatataggaa ggatattata tatctgatta gatatagata aatcaatatt
     2641 catcaaatca tctatatcaa cattgaatat cttagctatc tcatttaagg tttttaattt
     2701 tggtgtatat tttccttttt cccattcgct tattgaggat gaactttttc ttcctagttt
     2761 ttcggctagt tcttgttgat caatattata cttttctcta agaaacttta gattttcagc
     2821 gaacatagta acacctcctt gagttaattg taacaccgtt tcggaaaaaa tgtaacaggt
     2881 ttcttagaaa atattttagt gtttttaaag aagtatttac gcaaaataga aatcgatttc
     2941 aggaaaactg aaatatgcac ttgacttcgg aaaaaccgaa gtatataatt tagtcagaaa
     3001 gttaaagaga ggaggcgaat aaaatatgga taccgcgaag aaagaaaaat atacattgag
     3061 acaattaaga gctttaaagg gttattcaaa agaagaactg tcaaggaaaa gcaaagtgac
     3121 atcaagaaca atatttattt acgaaaacga tgtagataaa atgaggaacg gaaagtacgc
     3181 cactctagaa aaaattgcta aggcattggg tgttagagtt tccgatattt ttttagaccc
     3241 tgattcggaa aaaccgaaat caataacagg tgaaacaaaa caagtcagct aggaggtgtg
     3301 aatagtggaa gagaagaata taaaagtacc gactcttgaa gaatatacaa aaattgttgt
     3361 cgaaacagac gagcagaacc cgaaaacaat cgcagttatt acggcgaatg atattgaatc
     3421 atgcgaaggt tttcgagttc gaatgacccc tagatatgat taatgttctt tatcacgtgg
     3481 aggtatagga tcgtttccaa aactatcttt tgattgtatt tgtccattct ttttttggac
     3541 aataaactct gattgctgtt ttttagaaat ctttttacca tactcaacag catctgattt
     3601 attatcaaat agttttgtat cttcggaatt accttcacca cgtacagccc atttgccatt
     3661 tctaggagat acccattgat ttttacccat aacaattcac ctcgctttca agttaattct
     3721 attaagaggt gaaaagaaaa caaactgatg gaggtgagat tgtgagtaac aagccaaaaa
     3781 tcactttgaa tggcacacct aatcttcaaa gattagcaga tgaaatggct agaatacgtt
     3841 ctagacattg gggagttact gtggtggcaa ccataattga acaaaaagaa aagcccacac
     3901 agccggcaag caagtagtgg gcaccataga acaataatat tatatcacac actcgccact
     3961 tccgaaaaga ggagttgctg ctctcctttc aagtttgcca aagtccacgt ttcttcattt
     4021 tggcaactcc tcttcttgga ggtggtgacg gcgagagacg aaggagggat gacatgaagg
     4081 aagaatcaaa aatagggatt ttgaatgaga acaattacac aagattaatt attgaaacag
     4141 aagaagggga aaaagtagca gaagttacat tgaccgatgc aactcctgct gacggttatc
     4201 gtattcgatt aactcctaaa tatgattaac cttttggtgg gtgtggatcg tttccgtgac
     4261 tatcacggct ttgaattttt ccatctctgc catgaataaa tagctcagat ccttgatttt
     4321 tagaaatctc tctagcgatt tttactgctt ctgattttgt attagtatgt gcagtcgctt
     4381 tagaatttcc agcacctttg acattccaac caccattgga attaggtaca acatgttgat
     4441 tttttcccat agttttcacc tccatttcta tagaaatatt ttatcaaata gaaatggaga
     4501 aattcaataa acgaaaggag ggatcaaatg acattacaag agcatcaaca cttgatgcga
     4561 aaactaaatc aggaatacca cgaggaaatg aaacctagat tgctagggga acaatggcgt
     4621 gaacgccaga agaagtggtt agaaataaaa aagtgactca gccgtccaaa gcaatgagtc
     4681 acaaaccaaa aattatacct aaggagattt tatcacatga ataagaaaat tgaaaatctt
     4741 atcgaagaat tgaaacgtga atgccaaaag caaggtgttt ctattatttg tacagcccaa
     4801 aaagaagggg aacttaaaag tctcgtttat ggtgagacaa cagaaatttt actttgtctt
     4861 gctatgcaag aagaacattt agatgaaaat ctcccattgt cagcacatat tatgcgtaga
     4921 attgctgtgg atgcttacga acaagcgaaa aatgaagaag aaaatcaacc ttcaaatcat
     4981 acttttgtta ttaataacaa ggaagattta gctgatgtga tgactcgtat tctcaagggg
     5041 gaatttcaat gatgaatgaa aaaacaattg atctactcat tattttattt ttcacgttag
     5101 tgattgtagc gaaaagttat gtaatctttg gcttgttatt cgcaattacc atgcttgtgc
     5161 tttgcgtgtt agcaagcaga aaagaggtta aacatgaacg agttagcaaa tcttgacaac
     5221 tatttaactg atcctgatta tgctaaacca ccatatgaag cgccaattga tgaggaggat
     5281 gaagatgagt aaatctacct tagaaatgag ccatcaagaa tggctcgaag accgcaaaag
     5341 aggtattggt ggctcagatg ttgcaaccgt acttggatta aacaaataca aatctcctta
     5401 tcaattgtgg cttgagaaaa cgggtcaaat tgaattgaaa gatttagaaa gcgaaccagc
     5461 ttattggggt aatgttttag aagaagtggt tgctaaagag tttcaggaac gtacaggcaa
     5521 aaaagtacgc agaagaaacc aagtatttga acatccatta catccatttt taagagcaaa
     5581 tattgatcgg gaagtagtgg gagaaaatgc cattctggaa tgtaaaacag ccaatcaatt
     5641 tctcggaaaa gagtgggaag gtgaagaggt accgcttagc tatctctgtc aagttcagca
     5701 ttacatgaac gttttaaaca aagactattg ttatatcgct gttttgatcg gtggacaaaa
     5761 attcatttgg aagcggattg aacgagatca agagctgatc gatacaatca ctgaacaatt
     5821 agtagagttt tgggaaacga acgttcttgg aggtatcgag cctgtaattg acggaagtgg
     5881 agcgactgct gacttcttaa aagaaaaata tgcagatgta gaagaaaatc aaacagctct
     5941 accatcacgt tttgatgaac ttatcgagca aaaaagagaa ctcaagcgga cgaaaaaaga
     6001 aattgaatca tctattcgtc aagtagacaa cgagatcatc agtgagctag gtaaacgtga
     6061 agccagtatc ggtatcacac aaagaaacat tatcagctgg aaacttgttc gtacaagacg
     6121 gatgaacacg aagaaactag cagagaaata tccagatgtc gcaaatgatg aagagattta
     6181 taacgttact gaatcaagaa ggctaaccga aaaggagatc aaataatatg gcaacaaatg
     6241 aatcgttaaa aaatcaattg gcagaaaagc cacagaaaca agttgcacca ggacagttag
     6301 ggcttaaagc tctaatgaat acaccaacaa tgagaaagaa atttgaagaa gtacttcatg
     6361 acaatgctaa tgcttttatg tcgaatgtta tgactcttgt atctaatgac agttatcttg
     6421 cagatagtga accgatgtct atcatgagtg gtgcgttaac tgctgcaaca ttaaatcttg
     6481 ggctagataa gaatttaggt tatgcatatt tagttccatt caatagtaaa aacaagcaaa
     6541 caggaaaatg ggaaaagaaa gctcaattca tgcttggcta taaaggatat atccaattag
     6601 cccaacgatc aggtaaatac aaagcattaa atgtgatcga agtttacgaa ggagaactaa
     6661 aaagctggaa ccgactgaca gaagagtttg agtttgatcc aaatggtaga acgtctgatg
     6721 aagtcattgg atatgttggc tatttcgagt tactgaatgg attcaaaaaa actgtctatt
     6781 ggaccaaaca agaaatcgaa gctcatcgga ttgctaacaa taaagatcgc gataagacaa
     6841 agttaagtgg tgtgtgggca tctgattaca atgcaatggc acgaaaaact gttttgagaa
     6901 atcttctttc taaatgggga atcttgtcca tcgaaatgca agaagccacc acatcggatg
     6961 agagagtcca aagggttcaa gaagacggca gcattattgc tgaaacagaa gttgaagaag
     7021 atattcctga aagaaaagaa gcagaggtta tatctgaaga aaatgaagat gtacaaactg
     7081 gattatttga tgcatctaat ccgccgttaa acaaataatg agggagcttt ctcccttgct
     7141 tttctagagg agaaatacga atgaacacag gatatgtcaa attacatcga aaagtgatga
     7201 attcattcgt ttggaccaat ccttatatgt ataaattatg gagcttgtgt ttgatgaaag
     7261 cgagtcatga gaatcgcaag atacttttta atggaaaaga gatacaagtg aacagcggag
     7321 aattcgtcac agggcgcgat gctatcacat ctgagatgaa cgaaggcgtg aaacgtgaac
     7381 atcaagtgaa cagcggttct gtatggagat ggctaaaaca atttgaaaaa aacggaatgt
     7441 tgaacatcaa atcaactacg aaatacagcg ttatatcaat aaaaaactgg tctttgtacc
     7501 aaagcagtga acaacaaatg aacatcaaac gcacaacaag tgaacaacaa gtgcacacaa
     7561 acaagaatga aaagaattat aagaatgaaa agaataataa aacatcatcg tcgcaaccac
     7621 gcaaaaagcg tgtttacgac accgactcag tttactacat tctcgcggag gagttattca
     7681 aacagatttg tcagaatcag gaaatcaaaa agccgaatct gcaaagttgg gcagataaca
     7741 ttcggaaaat gatcgagatc gacaagcgga ccgaaaacca ggtacgggga atgattgaat
     7801 ggagtcagca caatgtgttt tgggcatcga atattttatc tgctaaaaaa ttgcgagaaa
     7861 aatacgacac aatggcagcg caagcaaatc gtgattataa aacaaaacaa actaaaacgc
     7921 ttgaatacga gaaatttagc acagatgagt tgcctatttg agaggaggcg taggcatgga
     7981 aactgttggg gaaatcatgg aaaagctgat acagaaagtg cttgtccaac gtggcgaatg
     8041 tcctgaatgc ggacagcctt tgtatggatg gcgtacgaag aaccctgatg gctcagaacg
     8101 ttgtaagcca acctgtatgc aatgtgggta taaagcattg cgagttcagg aagacttaca
     8161 aacagaacga atttacaacg agagcctgaa agcaagagca atcaattttt tcaaaggtgg
     8221 ttctgttgtg cctaatcaag cgttgtttga ttgcacattg cagaattatc aaattgtcga
     8281 tcaagaaaca agacaagcgg ttgaagtaac caaacgcttt gttaattcag tcttgttagg
     8341 aaatccaagt caccttgttt taactggaaa acaaggaaca ggtaaaagtc acctagcgat
     8401 ggcagcggct tgggaagtct tgaagcgatc aaactacgat aaaaaaatct tatttatcgg
     8461 gttacaggaa atgctggatc aaatcaaatt ttcgtacaac aatcctgaac tcagaaaaac
     8521 gattgaggga tcgttgattg cagatatcaa aacagcggat ttagtcatca ttgatgatat
     8581 cggttcagaa ctaggaaaag atgcatcaga tagtcgagcg tttggcataa acacgctaaa
     8641 ttcgttcttg gatgcacgac agaacctagc aacgattatc acaacgaact tgcttggtga
     8701 agaactgaaa aaagcttacg gtacgagaac aatatcaaga atgtttgtca actctgatgg
     8761 atttacgatg gtattttctc aaacagcaga caagcgcata aaaccagtca aaggagcgat
     8821 cgcatgaatt tgactaaaca agaaaaaaga atctgtcgtc agataatgtt gcaaattata
     8881 ggtgatcgtg acatggacga attatctcaa caagagagtc gaatggttcg gaagataagt
     8941 aagctaatcg gtgcagatac gatggatcga tccaagccat tacccaaact gaattttgaa
     9001 tcatttacgt ttgagaaata tagccatctg agagaggtag gctatagtgt aaatgctatt
     9061 cgaaaagcac ttggggtagg aagtagtgta tgggcaaaat ggcggaaaga aaatgtaaat
     9121 gaggtaaatc aaaatgatta agctaatagg caaagagacg ctcaaggttt actatgtagc
     9181 ggaaacaaag gcagaagtca gccgttggct attgaaaatg tttaataaga ctagagccaa
     9241 tgcttcagta agtcagaaag caagtgtatc agaaacaggc atgcctgaag caatgtggat
     9301 ttcaaggagg aactgagatg gcaatgatac cgaagtttag agcgtgggat agagaaaaag
     9361 acagaatgat ttatcctagc acgacaggag tttgttttga aatgaatgat gatggtataa
     9421 gtgtgcttga tattgatgta gattatccca atgactatgg ttttcccaaa atagcttcaa
     9481 tcctcatgca atctaccact ctgaaggata agaatggtgt ggagatattt gagggggata
     9541 tagcgcttat cactcataaa tcaacgaact acgccgatac ttattggcac agttacgtag
     9601 aagtttttag agcaaaaaac ggagcctaca gaattcgcgg tgaacacatc tacgaaacag
     9661 aattatatag taatagaaaa caattgacgg tagcggggaa tgtttataat tcaccagaac
     9721 ttttgaagag agatcgattt atgactacta ccgaaaatcc agagttattg aaggaggaac
     9781 agcgatgaat aaacaggaat tgattgataa atatactgca gaaatatcta gattaagacc
     9841 ttattgccct aatagacatt taattagcga tcaacttaaa tatggtcttt ataaagaaat
     9901 cctagaagat ttaaaacaac tagacgaacc gcagaaacca gcggtgccta agtttgtggc
     9961 ggaatggata gaatacgcta aaaagaaagg cgatagtcta gctatttcat tcaagccgtg
    10021 gaacctctac ggtgttgagt atagcaagac tgatagatgg attgaagata atcaaggaac
    10081 gtttgctcgt gcttggctaa ttggctacga ggtcgagaaa gagccgttgt attatgtgaa
    10141 gttgccagtt gtgtatttta atcattggga tttagagacg tatctaatga aagatgatag
    10201 aggaaatata acaattgcag acaacaacga ttttgatgat atgaaattta cggaatcaga
    10261 aataaaagca attgatgaaa gatactggcc atttgctgtg ccagtggaag aggtggcgga
    10321 aggatgagca atcttaaagt tggagatatt gttttttaca aaggtgacga aggcatcatc
    10381 cgagaagtta tgacggatgg aaaagaaaat ttttataggg tagatgtcag cagaaaatct
    10441 atactctacc tgtatgaaga cgaattagat ttaggtactc aaaaactcaa cgacaaccag
    10501 aaaatggtgt ttgattatct taaatcaaac gttgaacaag gtggcaaatc agttatgtat
    10561 tcgatattcc ttctaggtga ttgggactct cgaattggag cagcaagaaa cgttgatata
    10621 gattactgtg gattaaatgg taagcaggaa gcagaagtcc tatcagcatt cgctcaatgg
    10681 ggattagaac aggaggaagc ggaatgaaat acgaaatacc actaagtgaa gcagacgtcc
    10741 agtcaattat taacggtcgg gaggttaata aaaaacttcc tgatggtact gaattagtca
    10801 tcagacaaag ttatttgaaa gatatggcag ctccagtatt aattgatcgt tttaacgtga
    10861 ctgattctgt ggtagagaac catttaaaag aatttcgatc aagtatagac gacactttca
    10921 gattagggag ttgattgaca atgaacaaca gacatcgcag aataacaaaa ctaagaaaac
    10981 aggaactgaa tgtactaaag acaaagtttg aaaaagaata tggaatttca gcagaagaaa
    11041 catataaagt ggcaagtcag tgtgttgctg atgcgagtaa tgctattcgt aagtttggga
    11101 tttcgatatt aaatgatgat cgtaaatggg aggaaatgag atgaaactaa aagacggatt
    11161 ttacgctagt agtcacggca tcggcggttt aatgctagat atgccgacaa agaatcctaa
    11221 aacacgtaag aaaccaaaag tcaaagtcgg tgacatggtt cgctgcgaag cagaagggtt
    11281 catctatcca tttcgtggat atgtagaaca cgtctataat cactcagcaa tcattcgtat
    11341 tgaaaacacg atggaatgtg ataaatggac agctaaaagc aaagagaatt tagcagtggt
    11401 gagattggtg gatattgaac taatcaatga caaataaaaa agccggatcg ctccgactga
    11461 ttcaataaat tccacaagtt tattatatca cataaaaggg gcggtttgac ttgatgcaat
    11521 tgttacgaga ggtagctttc aaacagacaa gatgtaatgc gagagatgtg ctgaagaact
    11581 ttcggcgttt ggagcggatg gcaggtcgct ctttgataga tattaagtcg ccgattatta
    11641 cggacatgcc gaaggcaccg aagcacggca ataaggcaga agacgcgatc attcagatga
    11701 tggatataga agcagagaga gacgcgattt tagcggcttt gatggcgctt agtctgatta
    11761 gtcgtcagat actctactac agcttttgtg tgccagatag cttctcaaac tacaggatta
    11821 gccgtgaagt gggttattca gaaagaagca tacaacggat gaagtcggaa gctctgatag
    11881 agtttgcaga agcatataaa catgggaaaa taattgctta taaataggag gactatataa
    11941 tgtggaaaga ttatgtatca ttgaaagagt tgaaaaaaga tcttattttc aaaaaaatcg
    12001 tagaatggtc agagagtgaa ttaattttag aagatggaac caaaatggaa gttgtatgta
    12061 gcgaatcaga ttgctgcgca tgggccgaag gtgaattcaa aaatgtaaag cttgatgcag
    12121 tgattacaga tataaagatt tttgataaag gtaaccgtct ctataatggc gatggacata
    12181 gttcttatgc cgaagtcgtt gtttatcata atcgaaatga gattgctaaa gcggaatgta
    12241 cagcaaacga tgggaatgga ggctactatt acagtgtctg tgctttaaaa gtcaaagaaa
    12301 aactttgtgt agtgactgat gcataaaaaa tggcggtttt ttggcggaat gatggcggtt
    12361 tttagctatt taccagtgat attatggtag tgtcgaaaga ttagtgatag gtctgagaca
    12421 aaataaaatg taagggagga aatctccctc atcgtttaat taagcttcga tagacagcag
    12481 cggaaatatt aagaataagg atgtgaattt taactccttc taaattgttc ttattatcta
    12541 tcatccgttg ctgtctattg ttattatgtc actgtggcgg aaagggtaga cgcttaaaaa
    12601 taaggtcaat acgtcgaggg atagccttaa cgttttatga tttgaccatg caaggttcga
    12661 ttccttgcca gcgacttaga cgaaaggtag cttaaatatt aaccacatca acatcgtcag
    12721 cgagttgata aaggtaacta gcagactcta ggatttaagc cagtcttacc gattagtctg
    12781 ttatagtagc aagcttgcta gaggtagctc ctctggttga cgtgcagctc agttggtaga
    12841 gcgcctgact tttaatcagg aggtcgccgg ttcgaatccg gtcacgttaa taaagaacct
    12901 acggaaacaa tcaatcttat cggatgccga ttggttggct gaattaagca gtgtgtctgt
    12961 gaatcagtta ataggcataa aatactagca cagacgtgtg ccactctcag gtgtaggtta
    13021 ggagagaaac attagcaacc gagggttgga aatgggcgct caaagtacac gagcaaggcg
    13081 aggtcgatag taatcgatgg aatcggtgta ggttgctatt acataattga ttgggttaga
    13141 ttgagttttg ggattcggta caaatgaatc gtcaaatgac tcaagcacag gatcggaaac
    13201 gtccctgcct gtgcattaca tattagatca ctcgttgagt ggtcttttta ttttagaaaa
    13261 gagaggattt tgaaaatgaa tcatgagaag tttatcgaaa aatgcaaggc tattgtacgt
    13321 gaaagaattg agaatgagat tgctgaccta agtggagcag tacctgagtt tagtgttttc
    13381 atagtctggt catgcaaaac actacagaat agcaaagcat tagtcagcgc tagcttaaaa
    13441 ggagcaccgt attttgaaat tacgttgaac ggggacaaag gtgaaatcta tgtagatact
    13501 tatctcaaaa aatcaaatga atgtatcaaa gtctagcagg tgctaggctt tttctttaca
    13561 taaaggagga atgatctcat gaaacaatat accgctaaag atttcgagga aatgaagcga
    13621 ttaaagaagg actatgaaga agttgatatg gagctaactg ttggagtcat tcaacgaaga
    13681 ctgcgggtcg gattagagac agcaaaggct atttacaatg atctaaatgc tattgaagag
    13741 aagaatggct aatgaggaac tactggtata tatcgctaac taatgaatat cctcgaacca
    13801 ttgatgattg ttcagtgcgt gttgtgcgtt ctgtacaaat caaagggaag tactctattg
    13861 tcgaaatggg gagagaagca gaaccatgtg agattgatgc gtgcaagctc gtttattgcg
    13921 gtcatggttt ctatgatgaa ccaaacattc aaaataatat taacaagaat ttgagggatt
    13981 agaatgcaag aaatggctta aaaatctcca atcaggacaa atcaagttag acaaagtttc
    14041 cgatttaaag atattaattg aagcagatct aatgttgaaa gatattgaaa attagaaaac
    14101 aaaactcaac ctaagaagat tgcgaggtgg tgtgtattga atggcaagac aacgtgatcc
    14161 aagacgtgat gaagccaaaa gaatttggtt agaatccaac ggagaaaagc agttaaagga
    14221 aattgcatct gaattaaatg tttcagattc tcaggttaga aaatggaaat cgcaagacaa
    14281 atggagcgct gaattgaaaa gtaacgttac caatggcaaa agtaacgtta ctaatcaagg
    14341 tggcgctcct attggtaatc aaaatgctaa aggtaacaaa ggaaatagcc gagcttctcc
    14401 gccagtgggt aataaaaacg ctttgaaaac aggcgagtat gaaaccatat tttttgagac
    14461 actaagtgat gaagagaagg acatctattc tagtctgaat gataatcctt cttttgtttt
    14521 gtctgaagaa atacgtctac ttaagataag acaatttcgt atgatgaaga gaatccaaca
    14581 agctgaagct ggactaaatg atgaagaagt cgaacgattg cagcagctaa gaaagattaa
    14641 aaatccgatt gaaaaaaatg gtaaaaagct agaaatcaag cgtgaggtta tgcaagatgt
    14701 gcagattagc agaaaaaaac atcgcaaaat tgatgatatt ctttcaattg aagattcatt
    14761 gactcggatt agcaaccagt tagctaaagc catcaagcaa atgaatgaac tttatatgaa
    14821 tgaatacaga actgatttaa ttaaagctca gactgataag atccaagctg agacaaatga
    14881 aattggcgga aataattcag gtgaagaaat agaagaatgg aaacaggcag ttttaaatgc
    14941 cgcaaacaaa cgggcggtga aagaaaatga ataatgaatt tattcctttt gctgatattg
    15001 gttctgccat tgattattac tatgataaac cagtagcttt ttgccaagat attttgcatt
    15061 tgaatcctga tgaatggcaa gaaaatgttt taaatgattt agctgaattt tcaaaggttt
    15121 ctgttcgttc tggtcaagga gttggaaaaa cagcattaga agcaggagca atactttggt
    15181 tcttaacgtg tcgaccctac gctaaagtaa tagcaacagc tccgacaatg aagcaacttt
    15241 acgatgtact ttgggcagag gtagctaaat ggttaaatga tagcttgatc aaaaacttac
    15301 tgaagtggac aaagaccaaa atttatatgg ttggtgattc agagcgttgg tttgctacgg
    15361 ctagaacagc gactaaacca gaaaatatgc aaggttttca cgaggaccat atgttgattg
    15421 tggtagatga agcttctggt gtgtctgatc caattatgga agctattctt ggtacgctat
    15481 caggttttga taataagctg ttgatgtgtg gaaaccccaa taatattgaa ggtgtttttt
    15541 acgattccca caattcagac cgtgataaat acagagttca taaagtatca agctatgata
    15601 gtaaacgtac aaacaaagac aatatagaaa tgattcttaa aaaatatgga aaagaaagtg
    15661 atgttgctcg tgtccgtatt tttggagaat ttcccaaagg tgcgttggat tcatttatca
    15721 gtcttgaaac ggttgaattg gctacagaaa aacaaattag tgattcttta gtcaataaaa
    15781 caacggttgc tcatattggt gttgacgtag ctcgatatgg tgatgattct acgattctct
    15841 ttcctagaat tgctaccagg gcattggagt atgagaagta ttcaaaacgt agcaccatgg
    15901 aaacaacagg atatgtcatc aacatggcca agaatctaat gagtcaatat ccgagtattg
    15961 ataaagtgat gattaaagtc gatgacactg gtgtcggagg tggtgtaacc gaccgcctag
    16021 aagaacttat agaagacaaa cattatcctt ttgaggtgtt tggagtgaat aacggttcaa
    16081 catcagaaga cgatttttac gataatttag gtactcaact atggggaaac atcaaggaaa
    16141 tgttagaaga aaatatgaca gcaaatctta acggagaaca gcctgttatt gaattgcctt
    16201 ctgatagttc gttaatcaaa gaattaagta ctcgcaaatt caaaatgaca agtagaagtc
    16261 gtatacgttt agaaagtaaa gatgatatga aaaagcgaaa tattggtagt cccgatattg
    16321 ctgacgcact ggctttagcg ttttatgagc caccaagtca ctatcaattt attcaatttt
    16381 aggaggtgag cttttgatta gtacagtatt atctttagag agatataaga agctacgtgt
    16441 taaatatgca acacaaattg aagatggaat gtttgatccg aatggtttta tagaagatat
    16501 gaaaccattt tttgctgatc gcgaaagaaa atatctagct tatactagcg aaaagaatga
    16561 aatagataat agaccaaagc ctaacactga tattgtaaaa gttaataata aacttcatgc
    16621 tggtatgtat tcaattgtcg tagaccaagc agtcaatcat tttactggta tacctatcaa
    16681 atgggattac gatgtatcgg aacaaaaaag aacactcatt caaagattaa aagataaatt
    16741 cttaaaaaat gatatagaac ttccgacagt tccagaagct tttaacaaat taacaagcaa
    16801 tcttgattcc atgagattcg caatgcttga ttctgaaact gcaacttttc aaggagcttg
    16861 tggagtagct ttccgattgt tagagcctgt ggaagaagat gatggttgga agttaagagc
    16921 aagtaatatt gaaccttgga gagcagaaag atatggaaat gccggaatct atatcaaaga
    16981 aaagtatgac tcttaccaga aaaaattttt tcaagaaatg aaagttatga caagaaataa
    17041 aattctgaca tatgcttgct atggtgattt gaattttgtt acaagcggaa cgttcaaaaa
    17101 aattgatgag accgataacc ctttggggac gattaccttg gcagaattta aaaataatac
    17161 gaatcgttat tgtgattttg aagtagctga ggaaattgga gatgcaattg atcgtgcttt
    17221 gtctgatcaa caaaacgaaa tcgaacaatt taagcttgcg tacatgcttg ttactggcac
    17281 aacaatgagc aaaggcactg ctaaagaaat gatgaatcag ctagggatta tcaacttaaa
    17341 agaccctact gcaaaagctg aatatgtcac aaaaaattta gcaaaagatt tcaatgaata
    17401 tcatatggat ctattgaaaa aacagtttta caccatttgt aaagcaatcg attttaacga
    17461 tgaggtgttt aaatcaaaca gttctggaga agctcgcaag tggcaaatca ttagcctaga
    17521 agcgaaaaca aatactaaag agcaatattt tagagaagga ttgaaagaat gcgcagaaac
    17581 aattgctgct tttcttaagt ttcatgacaa agtagaaatt gagcctgaaa aaattatttt
    17641 tactttctct agatctttgc caactgattt aagttattta gctgaagctt tacctaaact
    17701 tgcaccatac gtatccaaac gaactattca gagccaaatt ccatttgtaa cagatgttga
    17761 ttatgaaaat gaaatgatgg aattggaaag tggaagtgct tatccagata gtgaatacaa
    17821 ttttggcgga ggtggcaata gtgacgatag aaacgaagta ttggaccaaa cgtcgagaac
    17881 tggaggatca agcaaggctc aaacaagaaa atcagacact taaaaaatta actagtgtat
    17941 ttcctgaagc actgaaagag atacaagcaa aactattatc acaagctgac ttacacaata
    18001 tcacttatcc agaaatgatg gagttttata gtacaagtaa tcagaaaaaa tatcgtgaat
    18061 atgtggaaaa aaattataag tcattaaaaa tgtatgatgc aaaatacaaa gagtttatcg
    18121 atgaattttt tccaccattt gactatgcaa aagtcaatcg cttattacaa atacgatcag
    18181 atgtatttaa aattcttgca gaatatgcga tggatgcaga tgtgaatcaa tatttttctg
    18241 atcgcttaga ggaaattctt caaagaacat attcttctaa tgctaatgtt tttgttcaac
    18301 ttttaaacgt tgatatacca aattatttac cagaaaatga aattaaacat tatttgaact
    18361 atccatggtc aggaaagaca ttttcaagaa gactttgggg aaatatttca tcgcttgaac
    18421 agaaactctc taatgctatt gtaaaaagtg ttgctagtgg agaaggcgtt atacacgcat
    18481 taaacaccat gagattagac tcagaaattt gtgacatgtt taagttagaa gaatcaaagt
    18541 ataacaaagc gatagaaaat ctcgttcgaa cggagtatgc aaaatttgca caagatggta
    18601 ttgaaaaatc atatttagaa acaggtattg aggaatacaa cgtattgact gcaaaagatg
    18661 agagagtttg ccggatttgt ggaggaaagg caagtaagaa tccctataaa ctgaaagatg
    18721 ctgtcatagg tgaaaatcga gcacctttcc atagtcgttg tagatgtacg gatgttccta
    18781 atttaccaaa attaggaaag gatattgatg aagaatatga ccgtttattt ggcgatttat
    18841 tagatgagtt tgcacatgat tcttttggaa ttaatttgaa acggaggaag tagaatgaaa
    18901 gatttttttg aagcagtact aacaattaat gtaaatgctg atattgcaga agcctacaaa
    18961 acagctattg agtctgagaa ccatcctaat ggcttgagag accattggaa tggcaattat
    19021 gcctacgtgg ttattggcga tcaaactgtt aattatcaag ataatactcc agttgataag
    19081 aataccgtta atttaacgat tcaattatta tctcattcat taccaaattt aaaagaaaca
    19141 gttgattggt atgaaaagat gggatgtatt gttgttagaa ctgactacaa agaaggaaag
    19201 tctagtaatt aggctttttt attttgtccg aaatgacgtt aaactagcgc aatactgggc
    19261 ttggttgaat ggtggggcgc aactattaaa actcaaagca atgcggggcg tgaaaacgaa
    19321 tcgtggggcg aaaggagaat gagcatgaaa cacaaatcat taatgccaat gaatttgcaa
    19381 tactttgccg aaggtgacga tcaaaagttt tcttttgatg acttcaaatc ttttgtggaa
    19441 tccaatgaag aagctcaaaa atttattcag tcacaatctc aaagtgttgc cgacaaacaa
    19501 ttggaagctt ggaaacaaaa taacttagat aaaattaaac aggataccat caaggaatat
    19561 gaggaatcta agaaaaacaa gtcacctgag caaattcaac tggaaaaact acaagctgaa
    19621 tttgaagcag aaaaagcgtt gcgtgtgaca agtgataata aagcatttgt tgcagaacaa
    19681 attgctggat tagaactaga tggagagtta aaagagtcta tttctcaatt tatgctaaat
    19741 aatcttgtta gttcggatac agatttcact aagaatgctg ttgaaggttt tacaagtgtc
    19801 ttgaatgcaa ttaatgagaa acatgcagat gcattaaaag aactacaaat gaagtctgca
    19861 tttggtggaa ctcaacaatc gaataaccag gttcagcaga acaatgaaac attaacaaat
    19921 ccagaagaac aattaggaca aattcttcaa caatttaact aggagagtga aaaattatga
    19981 aaaaaacatc tttaaataat ttagagtatt tggatatttc accagcgatt aatgctatgc
    20041 aagtaccaaa tacacctttt ttaagctatt tatttggtgc tggaaaaaca gagccagcaa
    20101 actcgacaga aattaaatgg cgtgaatatg atatcaacaa cgatgattct tctgaaaaac
    20161 ttgagggcgg agaatatcca gatgctgaat caggtcgaac ttggtttaac aactatactg
    20221 aaatttttag aaaatcaacc tctgtatctg gtacattaga tgctattaat gtgaatggag
    20281 tcggaaatga attaactaat caagtagcac tacgtggtat ggaaatgaaa attgatttga
    20341 accgaaaatt gattactggt gtaaaagctg atgaaaatgg ttctaaaggt cgtcgaatga
    20401 atgggatttt gaacttgatc aattcagcaa ataaggcaga aacagccact gcgggtgcag
    20461 taacaagaaa agatatcgat actttattta aattgatgta tgaaaaaggt tatatgggag
    20521 aaaaactatg cttgatttct ccagatatgc agaagttaat gactgatgag ttagatggaa
    20581 aatcaacaaa aattgttcag ttcggggaaa gagtaacttt tggattgcaa attggaaata
    20641 tcgtgtctaa ttacggtaca ggtattgctc tactagaacc atcattgcca aaaggaacaa
    20701 ttgccgcaat cgatactaat tatgtgaaac tacgtccatt acgtgaatgg agagcagaag
    20761 aacttgcaaa aacaacggat tctagacgta tcggtcttgt aggtgaatac tctcttgaat
    20821 acaatgcttc aaactctggg gcaattttaa atttaaagtc tgaataaaag ggagttagta
    20881 ctcccttttt tgataggagg aattacagtg gtaaaaaaag atgaaactaa aaaagatgaa
    20941 gtcgtgaaat atagagtagg taaaactaaa aattttgttg ggtttgttca tcctaaaact
    21001 cgtagattta tcacagcaga ttcaaataac gaatttatca tttctataga tgataaagaa
    21061 gcaattgcaa ttttggaaga tgcaattgat gttaatgaaa tttaggaagt gatctgatgg
    21121 atgaatcgct aaaaacggaa atcattgagt ctacaaaaga agattttcca gatttgagtg
    21181 aagaacgcat aactaattta ttagaaataa ttttgctaga aattgaatca tacaacactt
    21241 gtaaaaatga tatttcatgg gaaaagttaa aaagcgtgat tagtgaagtg ttgtataaaa
    21301 taataaaaaa tgaatcagaa aaaacagtat cttcagttag acgtggcgat acaacgatta
    21361 gttatgcttc aacaacaaat gatgttagtg agttacttct aggctatggt gatttgatac
    21421 gaagagttat tggttgtgga ggattggagt ttttttaatg aatgaagcag atattttaga
    21481 aactacttat gaagatagtt gtattattga aagactgacg gacattgaag attctaatac
    21541 aaatattact attcaagatt acaaaaaagt atatgataat cctatttctt gcgctctttc
    21601 acaaggtcaa atcgatggac tagcagtcat agaagatgga gagatggtaa atgtttcaac
    21661 tgacacatat aaattatttg ttcatcctaa gattaaacta aaaaaaggag atcgaataac
    21721 aataactcaa aaggccagtg gcttaatttt ttctctattt gctactaagc ctttttacta
    21781 tcctagtcat tgtgaagtga atttgatagg aagtgagaaa aatgggtaat ctcaaatatg
    21841 aatcaaatgc agaaaagatc attgagaatt ttaaaaatat gactgtaatt gctcaaaaag
    21901 aaggaatatc cttcgttaac gattcaatga ataaagtcgt tagtttagct aaaccattaa
    21961 ctcctgtaaa atcaggtaat ttaaggcgag gatatcgtgt agtaaaagct agaaaactat
    22021 caagcggtcg aattgttgga gcagttataa acaatgaaca ttattttaaa tatgtagaag
    22081 aaggtcatag gactaaaaat ggtggctttg tcaaagggaa attcatgtta actcgtgcaa
    22141 cgaatcttgc aaatatgtct tatattcctc gaagatttaa acaaatggca ataaaaatcg
    22201 ttaagaaagg aaagtaacat gaaagatgaa atcattgctg caatcagtag caaattaaaa
    22261 gaaatctatc ctgatgggac aatatatctt gattcagtta tgcagtcaac taaagatttt
    22321 tatttcgttt tatcagtaat ggaatctgga actgaaaatg taggaattga tattcaaaat
    22381 gtttctttct taattgatat tgcattgatt gataataaac ctaatagaaa tttaattaat
    22441 gaattagtct cacgttgtgg gacttttttt aatacgatta caatcgatga gcaaatatta
    22501 tttccaaaag cctatttacc tgatgaagca gatggtgttc aacatattcg ttttacatta
    22561 gaatttccac aatatattga atggagtgaa agataaatgg gagaaaaaag aagtaaaacc
    22621 ggaattattt ctgtcgaaaa acctacttgg tttcctttgg aagatgagac agggaatttt
    22681 ccggtatatg gtactgcgtt gccaatggga acagcagtaa gtatcaaacc aacagctaat
    22741 tatgaaacaa cacaagatta tggggattca gtggttcaag atcaatttac agcttttggt
    22801 ggtgcagaag ttgaactgga agcaaatgga tatactcata aagttttatc tacaattact
    22861 ggagggaaaa ttgttaaagg tggtgccttg cgttctggag aagatattgc gcaagatggt
    22921 gcgtttgcat atagacgtaa aaaatcgaat gggaaatacc gttatacggt cttttataaa
    22981 ggacagtttg ctctagattc agatgaaaca tcaacgattg aaggaagtaa agtaagtttt
    23041 actcatccaa cttggaaggg ttcatttgta gatgtaccag gacttggata tatgtattca
    23101 gttgatgaag atgatgaagg cgtggataaa gcaatgatcg gaaattggtt tacaaaagta
    23161 gcaattccaa ttgaagaagc agaactttca ggaggtacag aataatgtca aaatatcaaa
    23221 caacgattaa attaacgaaa aaagatgaag aaggtaaata tgagcaagta caatttaaat
    23281 ctgctgaatt tttaccagga acagttgtag aagatgctgc aggagttatg gaagaaatgc
    23341 aaacagcgac tgataaacaa tcagttaaaa aagctttaag tcgtgcttat tcatttattg
    23401 cagatacttt atttgaggga caatttactg gtgaagatta ttgcaaagga attgatgctc
    23461 gtgagattgc ctcattgaca ggaaaattat tgaagtctgt tactgcaggt tttgatgaaa
    23521 cttatacaga gacgaaaaaa aagtaagtga ggcgctcaag tcaccttcat ttaagtattc
    23581 gattacttac cgagaattag atataaagac gcaattactc gaagcaggtt ggacgttacc
    23641 agaaattgaa cgtactgact tggatgagtt aatgcgtctt tttgctttta gagatgcggt
    23701 aaaagagcat gaagatgttg agtactatga taatttcact caattttagg aggtgatact
    23761 ttgaataacg atgacctaat tctgaagatg atactagatg aatctggttt tactgccggt
    23821 atgaataatg ctgtcaaaaa gttgaactct tttgatgaaa caatcgaaag aaaaagtaga
    23881 aatagtggca gttcattagg tagtatttgg aaaatatttg ctggaagttt tctagctagc
    23941 ggagtaacta gaatcgtagg agctggcttt gatctaatca agggttccat aagtggagcg
    24001 gttgatcgag tagatacgat gaataacgct ctacgaaatt tccaaaatat gggatttagt
    24061 aattcagaaa ttatgaagaa tatcggaaag aatgggcttt tatctcaagg tattcaagga
    24121 cttcctactg ctttgaatga tgcgataagt catgttcaac ttcttgcttc ttctacaggt
    24181 gatttaactc gttcaactca aatatttaaa gctttaaatg atggaattct tggtttcggt
    24241 ggttcaactg atcaagttaa tgaagctgtt attcaattat ctcaaagttt ctcaaacgga
    24301 aaagtagacg cacaaacttg gaactcaatg atcaacgctc aacttggacc tactctttct
    24361 gctattgcta aaaagatggg aattacaatg ggagatctga aagaaggttt gtctcaaggt
    24421 aagatttctg ttgaagaatt ccaaaatcaa ttaatagaaa tggataccaa aggtggcgga
    24481 ggacttaaat cattaagtca aatcgctaaa gattctacta agggaattaa aacctctata
    24541 caaaatgcaa aaacagctgt tacacgtggt gttggtgagg taatagaagg attaaataaa
    24601 gcattagtag attcagattt aggtggattt aagggaatta ttgataaagt gggcagttca
    24661 atggaatcgt tcttaaaagt aattgctgca aatattccta cagcagtatc atttttaagt
    24721 aatttattta acgaaattca aaaatttggt tctgctttga aattcatgat gccctttctt
    24781 gttcctgcag ctaccgcttt tggagcgttc atgtttcaac ttaaaggtat accagcaata
    24841 ataaaaagct tcaataattt taagaatgcc ataattggcg ttggaaattc attaaagatt
    24901 atgggggcaa tagctgctgc taattcattt gttttaatta ttggtgcagt cgttggtgca
    24961 atagctgttt tcggttactt tatggcaacc aatgaagagt ttagaaacaa ggttatatct
    25021 atttggaatg atgtgaaaga ttccgtaatt ggtgtattaa aaaatataaa ggactgggga
    25081 attgatactt ggaattctgc taaagaaatg gcatcaaatg cagttgaggg tgtcaaagat
    25141 gcttggtcag gaacaaagga atggttttct aacacctgga aaggtattaa ggatggggcc
    25201 acaggtttat ttgataaaac agtagagact tcaagaaatg cagtcgatag tgtaaaaaat
    25261 gcatggtcta atatgaagaa atggttttct gatacttggc aaagtataaa agattcagcc
    25321 agagaaaaat ggaatgaaat taaaggttct attatgtcgg ttgctggtcc attgattaca
    25381 ggtataaaga atgcattttt acatgttact ttttatctag agaccttatg gaataattta
    25441 gttgagattg gtaaaaacgt ctttgagatt ttaaaaaatg ttatacttgc gccggttttg
    25501 tttattacct ccatgatttc tggtggatgg gaagaaacaa aaaataatat gattgctgtt
    25561 tggaataata ttaaagaaag tgccataaat atttgggaat ctataaagaa tatatttgta
    25621 agttatttta caaatattta ttttgctgca ctcaatattt ggacagggtt caagcttaca
    25681 ttgataaata tttggaatga agtggtaaat caagctaaat cgatttggtt aaacataaag
    25741 tattttttta ttaatctttg gattgatata aaatattttg caattcagaa atggattgaa
    25801 ttgaagtttt ctattattca aacttggatc gatttaaaat ataatgccat tactacttgg
    25861 aataatatta aacagttttt caaagatact tggaaaaata ttaaagatac ggcatacaat
    25921 acgtggattt ctataaaaaa taccatgatt aatacatgga ataacattaa ggactctttc
    25981 tggaatattg ttactggaat tgttaattct gctgaaaatg catggacaaa tctaaaaaat
    26041 ggtgtttcaa atgctattaa tcgggtaaaa gaaatcttta attcgttaag ggaagtcaat
    26101 ttatttgaaa ttggcaagaa catcattgat ggacttataa atggtgtaaa agaaaagtgg
    26161 aatgctttga aagatactat caaaggtatt gcaggtaata tcaaaaattg gattaaagga
    26221 gctttagata ttcattctcc atcaagatgg atgcgtgata tggttggtaa aaatattgtt
    26281 caaggtatta tcgttggtat tgataaagag caaagtaagt tagatcaaac catgacaaat
    26341 ttagtaaaaa caccgtctgt tcaacctgta gtaaatggaa taagtcacct accaattaca
    26401 caaacaaagc aaaatatatc tgctagtgaa acaaaagaaa ttcatttaca tttaaatgtt
    26461 tatggagatt tacctgattc aatggttcgg aagattacca caaaaattaa aacagaattg
    26521 acaagacaaa tgaaacgaga tgctggtgca gtaggaggaa cattatatgc aacttaagag
    26581 aggacaattt tttattaatc aacattattc ttctgaattt aatgtgtata ttcaaaacag
    26641 gcctgcttct gtttcagcta gtcgagtaat tgaattgaga gagcgagaag gaaatgattc
    26701 tatcattatt gataaaggct attacagaaa tgtgactaga aagattgagt gttactataa
    26761 agcaccttca attgatgtgg tgcaggagtg ggaagatcga atcactgaat ggttagatat
    26821 gtcgtcttat agtgatttta ttctttacta tgatgaacaa tatatttatc aagctgtagt
    26881 aatagaagga cctgaattta aaggaacaag aaaaacagga aatattgtcc cttttgaatt
    26941 tacagtgagc attcgaccat ttaaggaaaa ttacaatggt agatttacta ttcgacaaac
    27001 agaaactttt gaaatttata acccagagaa gtattcttca aaaccgctta ttaaattgag
    27061 tggttctgga gatgcttctt tttatattaa taaggacaaa tatgatttga aatcgttgga
    27121 cagagaatta tttatagatt ctaaattaga agaggcttac cgaaaattag atggtaattt
    27181 agaacatcag gatcaagtca ctttattttt agattttcca tttttatatc ctggaaaaaa
    27241 tgaaattaaa tggacgaaaa atattcattc atttgaaata atgcctaggt ggtggagaaa
    27301 agtatgaaac caagaatata tagtcctact gaaacagatt tctcaacgaa tggcttagga
    27361 attttaaagg attgtacaag atgtgaaata tatgaagtag ctaatggaaa atatgaatta
    27421 gagttggatt atcctttagg aactagattt gatgaatatt ttgaaaatga ctatcaaata
    27481 aaagcaaagc caaacgatca agaagagtat catatctttt ttattgatga taaagatata
    27541 gatacttttt taaatacagt aactatttat gctcagagtc gtacaaatcg acttggaaga
    27601 cgggtagtca ctcttgcgga agtagactct aaaactggtc aagaagcgat atcaattatt
    27661 gaaaccaaaa tggataaaaa atctgacata cgactttatt ctgatattac ggccgtttct
    27721 agcacaatct ttgaagcgag aaatgtttta aattgtattg ctggtgaaca aggatcattg
    27781 cttcaatatt ggggtggaga aattaaacgt gaaccattta agctttcttt gttaaagcga
    27841 agaggtcgca ataatgttgg aacgattcgg tatggaaaag atatgtctgg tttaaaggtc
    27901 aaattagatt ggacaggtat aaaaacaaga cttattccat atgctgatcc tcaaagtgag
    27961 gtaggtacga ctaatcgaat ttatggttcg ccagtagata gtgcctatat taataactat
    28021 cctgatgtgt atacagagca tgttcagttt acagaagaac aaggagtaaa agacattaag
    28081 agcttaaata aaatagctaa aaattacttt aaaacgatca atcctggctg tgataagcct
    28141 aaagtttcta ttacggttga atttgataag ttgactgata gtgaagaagc gaaagaattt
    28201 gcgaagatta gaaattatgg tctgtttgat acatttaaaa tatatcataa aaaatataat
    28261 atttatcttg aatcaaaggt tagtggacta caatacgatt ctttatctga aaaaactttg
    28321 aaattagaag caggagacat tcaagttgct ttttatcagc aacaagctgt aactattcag
    28381 gataaattaa aagattatgc aacgaataat tatatgagtg attttaatga ttatgtttct
    28441 tcaatgatta caggtcaagg cagtgcagga ggatatgtaa gtttatggcc aaaagaaaaa
    28501 ccttccaaca tctttattat ggataatcca gatttagaaa aggcaagaga agtactaaga
    28561 atgaataaaa atgggattgc tttttctaag aaaggatggc gggggccttt tacttcagct
    28621 tggacattag atagtatatt taatgccaat tttatacaaa ctggattaat caaagcagat
    28681 atctttcaaa attcttttaa caagactgga gatgtattga aattagttaa tggactactc
    28741 caaatttgga acaacaaaaa gaaaataatg gagttaacta aaaaaggaat ggaattttgg
    28801 aattctaagg gttcaattgg aacgattgga acaactgatt ctgctggtaa tccttttcct
    28861 ggggcttcta ctccaacccc tattgaagat aattctttag ttattcgtac aaatggagac
    28921 ggcaaatata ttttgatttc tcctaaagta ggaaaaggat tagttttatt aggaaatggt
    28981 aaagcaattt attttggaga cttagatgta caaggaaaac ttacagttaa aggaaaagaa
    29041 ataattcctg gacaaggtgg tggtccatcg ggaggtggag aatctactgg tgggtatcct
    29101 agtgaattaa aaacagatgc agaaaagaga gcttggagaa tttacgatat tttgtgtaat
    29161 aacggattta cgaaacaatc tgcatgtgga atattgggga acattcaaca agaaacagga
    29221 ggaacttttg atcctgatac tgttcaaata ggtggaccag catacggatt agttcagtgg
    29281 gatggttctt catatcctct tgttggtcca gcaacatggg atggaaaagt ttatgttcaa
    29341 aacttattta atgctgcagg tattaaagaa ccaataacga gcttagatgc acaagttcga
    29401 ttgcttattt ggacatttac aaatggacaa tggatgggcg tagtacaacc tacgacggtt
    29461 gatggattta aggcctgtac tgatccaaga caagcagcat atgcttttga acgaaactat
    29521 gaacgtccgg cagcgacaca tcctgaacgt caagattatg cagttaactg gtataacaaa
    29581 tttaaagatt taaaaccagg aggagctact ggagaagcag gactaaaaca tttagagtct
    29641 ttgattggac aacgaattgg caatggtcag tgttatggct tgtctgcaga atattcagga
    29701 tatctgggtg gttgtggcat gggtgctgga acaaaatatg gtttaactca tgtgatagga
    29761 aatacttctg cagcatctga tattggtatt gcctatgatt ggtctgctgt tggttggaaa
    29821 gtgattcaaa accctagata tgatcaatta gtagttggtg caattattaa ttgggcaaga
    29881 ggtggacaag tgggttcatg gtttgcagac ggaacttatg gacatactgg cgttatccga
    29941 ggcttagcta atggtcgtat gcaaacttat gaacaaaaca cagagttagg tatgatttgt
    30001 ggaaagttag atcgccagta ttatagtgca agtgcaattt cttccattgt cataccacca
    30061 aaatagggag gtgatttaat ggcaaagtgg aatgtcatat taagtacaac agaaccctat
    30121 aattacgtgg ggatgattca agttcgacaa ggcaataaaa acactgaagt tatggaagct
    30181 acaattgtcg aaaatggtct tccatatgat ttatcagaat gtaaggtata ttttgaatca
    30241 gttgttggcg gaaaatatcc agtccaatta gaaacaagaa ttgtggatgc taaaaaaggg
    30301 aaaatcaaat atatttttga taaatattcc atgcagtgtt tgcatcgaca aacagccaat
    30361 ttcattatat ttaaaggaga agacttgatt ggaacaactc aagacttctc ctattttgtc
    30421 atcaatgctg tttcaaaaac agaaggagaa atgggttctt attggcaatc aattgaagat
    30481 ttaattgctg atatgacaga ttttattaat gaaaataaag gcgattttac ggactggatg
    30541 aatgaaagga aagaagaatt tgatcgctgg agagaagaac aggagaatag tttccaagat
    30601 tggagagaag gacaagaatc agattatttg tcatggtttg aatcaatcaa ggatattttg
    30661 aagtctatcg atccaggtgg agtaatgtta gccgaattaa tggatgcacg tgtagatctt
    30721 caaggtgtac gccatgaatc gatttctgaa cgtttcctat ccgatctaaa ttatttgtat
    30781 caaaaaatga aagcagcact tttcacgatt gaatacggtg aaattgaagt gactgatatt
    30841 cttcaagacg atctcttttc agataatcac gaagtcgaaa aagttggaac tgtagaattc
    30901 ccgattgaag aaggagcctt gatcatcgca accgttgatg atccaaagca aaatgtgttc
    30961 actcttgaga aagtcggggt gatctaatgg ctaaaactaa acgaatgatg gaaacggatg
    31021 aaaaaacagg tgtacaacgc caattctttc caatcacaca tgcttccgca gttcttgggt
    31081 tagaagaaat aatagcagga gaagcaacag ttttatctgt taatggaaaa attggagccg
    31141 tcgtcattac taaagaagat ttgggattag agaatgttat cacagaatta ccctatgcaa
    31201 gtgaagaaga tgacggcatt atcacggcag aaatgtatca aaaaatttta aacagtggag
    31261 aaggtgacta cgtgttgcca gttgccacta tcgaccgttt gggtggcata aaagttggtg
    31321 aattattgac gattgatgag acagggaaag tctctgcagt cagacaatct gatgtcaatt
    31381 tttcgctgga gttaaaagaa aaactcgatt cactgaaaaa ttatactgct ggagaaaaca
    31441 tcactattga tgaagatgga acaattagtt ctacaggtgg tagtgggact ggtggtgtca
    31501 atcagtcata tgtagatcaa aaattccaag aagctgtaaa tcaagcagaa aattacacaa
    31561 acgaaagaat tccaaatttt acttttgaaa aaattgggga ggtatagaga atgacagata
    31621 tcgtaaaaat aaaacaaagc aatgtacagg tttatccaca aactcattgg aatgctata
//
LOCUS       DASHWW010000024        30444 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.024, whole genome shotgun sequence.
ACCESSION   DASHWW010000024 DASHWW010000000
VERSION     DASHWW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.024"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..564
                     /locus_tag="U2R64_001315"
     CDS             <1..564
                     /locus_tag="U2R64_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918143.1"
                     /translation="DRVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFF
                     YFRFEGVTGRKISLKDESSTTVSDANILANIILDFIFEHDIPFKNGYEILPQNEQYFF
                     YKCLTNRVCCSCGKKNADIHHVDSVGMGNNRKKINNSGRRFMALCRECHTKIHVEGFT
                     TFTTKRKLTAVVLKDSDLKRLGLNIIE"
     gene            572..1087
                     /locus_tag="U2R64_001316"
     CDS             572..1087
                     /locus_tag="U2R64_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEM8918144.1"
                     /translation="MDIEGYEGVYQVSSLGRVKSNRPNYVINKGYVNKEGFIMKPSDN
                     GKGYQIIFLSGKGFRDRRYVHRLVAFHFLKEAYFEGAEVNHKNGDKSNNTVENLEWLS
                     SDDNKKHARKNGLTNLKGPSKLTDLQALAIKRLYTNKLMSSGEIMKLFNVSRHTVLNI
                     ASGKTFSFLED"
     gene            1196..2047
                     /locus_tag="U2R64_001317"
     CDS             1196..2047
                     /locus_tag="U2R64_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEM8918145.1"
                     /translation="MADNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDI
                     QSFIGKSSTEADRKRKYRKEIEEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEK
                     DIENVTPPKKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESS
                     GKTYKNYLATIRSWARKEKSEPKNASGAYKRTGRREKLPEWAIDQEAYQKKKALERAN
                     RQSKAPF"
     gene            2059..2328
                     /locus_tag="U2R64_001318"
     CDS             2059..2328
                     /locus_tag="U2R64_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918146.1"
                     /translation="MKIDYLELINEIASYKTGEEIEILRDVYEQLDEAGIERIKNDRS
                     SWSKLRYYFALYIDATQLRNLAYTKLLFADCVKGLQKHLSELEQV"
     gene            2333..2497
                     /locus_tag="U2R64_001319"
     CDS             2333..2497
                     /locus_tag="U2R64_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918147.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDE"
     gene            2490..2792
                     /locus_tag="U2R64_001320"
     CDS             2490..2792
                     /locus_tag="U2R64_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918148.1"
                     /translation="MNKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVTGTAEQLASLTGLHEKIVRKRARCGYTDVKKRTFRYVEGSS"
     gene            2789..2950
                     /locus_tag="U2R64_001321"
     CDS             2789..2950
                     /locus_tag="U2R64_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEM8918149.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            2947..3255
                     /locus_tag="U2R64_001322"
     CDS             2947..3255
                     /locus_tag="U2R64_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918150.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK
                     "
     gene            3252..3563
                     /locus_tag="U2R64_001323"
     CDS             3252..3563
                     /locus_tag="U2R64_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEM8918151.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            3560..3778
                     /locus_tag="U2R64_001324"
     CDS             3560..3778
                     /locus_tag="U2R64_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HEM8918152.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            3789..4332
                     /locus_tag="U2R64_001325"
                     /pseudo
     CDS             3789..4332
                     /locus_tag="U2R64_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4471..4827
                     /locus_tag="U2R64_001326"
     CDS             4471..4827
                     /locus_tag="U2R64_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HEM8918153.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            4814..5032
                     /locus_tag="U2R64_001327"
     CDS             4814..5032
                     /locus_tag="U2R64_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918154.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            5029..5448
                     /locus_tag="U2R64_001328"
     CDS             5029..5448
                     /locus_tag="U2R64_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HEM8918155.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            5445..6002
                     /locus_tag="U2R64_001329"
     CDS             5445..6002
                     /locus_tag="U2R64_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEM8918156.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            5999..6295
                     /locus_tag="U2R64_001330"
     CDS             5999..6295
                     /locus_tag="U2R64_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918157.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            6372..6785
                     /locus_tag="U2R64_001331"
     CDS             6372..6785
                     /locus_tag="U2R64_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HEM8918158.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            7094..7246
                     /locus_tag="U2R64_001332"
     CDS             7094..7246
                     /locus_tag="U2R64_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918159.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(7243..7518)
                     /locus_tag="U2R64_001333"
     CDS             complement(7243..7518)
                     /locus_tag="U2R64_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918160.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            7972..8178
                     /locus_tag="U2R64_001334"
     CDS             7972..8178
                     /locus_tag="U2R64_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918161.1"
                     /translation="MLGQCFGNHARFDSLPATLNVYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            8374..8541
                     /locus_tag="U2R64_001335"
     CDS             8374..8541
                     /locus_tag="U2R64_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEM8918162.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            8567..8911
                     /locus_tag="U2R64_001336"
     CDS             8567..8911
                     /locus_tag="U2R64_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEM8918163.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            8916..9197
                     /locus_tag="U2R64_001337"
     CDS             8916..9197
                     /locus_tag="U2R64_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918164.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            9300..9614
                     /locus_tag="U2R64_001338"
     CDS             9300..9614
                     /locus_tag="U2R64_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEM8918165.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            9592..11286
                     /locus_tag="U2R64_001339"
     CDS             9592..11286
                     /locus_tag="U2R64_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEM8918166.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            11306..12484
                     /locus_tag="U2R64_001340"
     CDS             11306..12484
                     /locus_tag="U2R64_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8918167.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            12447..13133
                     /locus_tag="U2R64_001341"
     CDS             12447..13133
                     /locus_tag="U2R64_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEM8918168.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDAK"
     gene            13133..14293
                     /locus_tag="U2R64_001342"
     CDS             13133..14293
                     /locus_tag="U2R64_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEM8918169.1"
                     /translation="MTIKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            14303..15178
                     /locus_tag="U2R64_001343"
     CDS             14303..15178
                     /locus_tag="U2R64_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918170.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWARLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            15175..15486
                     /locus_tag="U2R64_001344"
     CDS             15175..15486
                     /locus_tag="U2R64_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918171.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            15476..15829
                     /locus_tag="U2R64_001345"
     CDS             15476..15829
                     /locus_tag="U2R64_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEM8918172.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            15819..16220
                     /locus_tag="U2R64_001346"
     CDS             15819..16220
                     /locus_tag="U2R64_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918173.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            16213..16617
                     /locus_tag="U2R64_001347"
     CDS             16213..16617
                     /locus_tag="U2R64_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918174.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            16629..17237
                     /locus_tag="U2R64_001348"
     CDS             16629..17237
                     /locus_tag="U2R64_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918175.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIATNCTGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            17257..17619
                     /locus_tag="U2R64_001349"
     CDS             17257..17619
                     /locus_tag="U2R64_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918176.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMSM
                     GKGSMDITVIQGAKAVYVAYRQANMVDYISFDEFIDKWDFDMEVAVAVYSTMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            17622..17804
                     /locus_tag="U2R64_001350"
     CDS             17622..17804
                     /locus_tag="U2R64_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918177.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            17822..21142
                     /locus_tag="U2R64_001351"
     CDS             17822..21142
                     /locus_tag="U2R64_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918178.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQSKGEFKTYESTMKDLDNEQQHLKSSASLVESEYKKWQ
                     ATAGQSATESEKLAKAQEYVGKQSDIAEQKIEVLKKQLDATQKEFGETSTEALEMKTK
                     LNDAEREFEELSNAAKNVDTSTVDDIGKKLDMGNLMEATDHLSVIGDKLIDVGSKSIE
                     AAGKAQAMQAQFKQVFGSLEGEAQDAVEGMAEEFGMLPNTIKPVFTQYTSMFKGLGYD
                     TKEAMELAGDSTQLAADAAAFYDKSMDDASESLNSFIKGNYEGGEQIGLFANDTQMAA
                     YAVKHNLIPATEGAKKASEESLLAVEKAQSKYADAIKKHGEGSLEAREAALKLKDAQD
                     KINEELGPQTQKWSDLDEATKQAVRVQYAEDMQKLAGATGQASRESDGLENQMTRAKQ
                     ALEDFYASLGEDILPVFIKGLQAGAKALQGLAEWWSKLDGPMKNFILALGGILALLST
                     LAPVITAVVTIVGTFGSTVLLPIIGIIAGVAAVIAIVITAFQNWGAITDWFSDLWKKF
                     TDWLGDTWESIKESASSVWDGVKETWSGFVDWVQEIWQGVSDWFGELWSGLVEGASNI
                     WQGVQETWQAFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGI
                     FDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNG
                     IWTSISTTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWN
                     SISSTASNIWSSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGIT
                     STISSKVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKI
                     SSVFDNLNISIPHIPLPHFKLSGEFNPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAG
                     PEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQ
                     QIIDSITKVQNDNASAWR"
     gene            21193..21930
                     /locus_tag="U2R64_001352"
     CDS             21193..21930
                     /locus_tag="U2R64_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918179.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFTLNDYVFSFEGLVVGTDIVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            21940..24231
                     /locus_tag="U2R64_001353"
     CDS             21940..24231
                     /locus_tag="U2R64_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918180.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            24255..26360
                     /locus_tag="U2R64_001354"
     CDS             24255..26360
                     /locus_tag="U2R64_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918181.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVIFSLDGTFMSEAGYYKHCYVEYRKGNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGNPNLMANINADSFS
                     QGSGALSVVDDGDEVVITLDPNHKLEVFKPKSQPALLTGKTYTVSVEIMLEGDFTGDP
                     SKIGLRYFKMPNWVPALTTPNALTATKGVWQKLTVTAKMTTAIDNAESWYVTLYNKDA
                     NNSLSGKLRLRHAKLEEGSTATPYQPNLLDAPYYLSKVALGENLVTNAKFPIITPNNP
                     ISGFDISEELIIGETYTVSLKGTKPANKEFHLYYGDANYQQSQSQYQATLLPVEGLAN
                     VWSATFTARNTSETTNLLRVALWQKPNSATYGTVQIDWLKIEKGNTRTPNISEYKYRG
                     TGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASIN
                     EVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTV
                     SIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIK
                     WRRNSSYGSDYTFAITYTI"
     gene            26377..26526
                     /locus_tag="U2R64_001355"
     CDS             26377..26526
                     /locus_tag="U2R64_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918182.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            26523..26969
                     /locus_tag="U2R64_001356"
     CDS             26523..26969
                     /locus_tag="U2R64_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918183.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            26971..27108
                     /locus_tag="U2R64_001357"
     CDS             26971..27108
                     /locus_tag="U2R64_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEM8918184.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            27146..27439
                     /locus_tag="U2R64_001358"
     CDS             27146..27439
                     /locus_tag="U2R64_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918185.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            27436..27660
                     /locus_tag="U2R64_001359"
     CDS             27436..27660
                     /locus_tag="U2R64_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEM8918186.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            27657..28682
                     /locus_tag="U2R64_001360"
     CDS             27657..28682
                     /locus_tag="U2R64_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8918187.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGA
                     ANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            28872..28945
                     /locus_tag="U2R64_001361"
     tRNA            28872..28945
                     /locus_tag="U2R64_001361"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28906..28908,aa:Ile,seq:cat)
     gene            28989..29930
                     /locus_tag="U2R64_001362"
     CDS             28989..29930
                     /locus_tag="U2R64_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEM8918188.1"
                     /translation="MSLKDDKPILRFNEQLEKLNDLGIYVADNEIHEAKNILSNHNYF
                     FKLLAYRKNYDKNEQKKYNISFLSIVDLAKLDMQLRYVLLPYCLDIEHSLKTYLMRLI
                     TNRKNKNGEYAENGYEIVKSVLADEDTPKDLKDQIFNGVRYRDSDGNLAFQEGFEKYY
                     NEPPIWVVLDLASISKIKFFVNYLANKQPNNNNLKMIKNNIGYVSYIRNSCAHNKPIL
                     LNLQRKSIIKNSVYANARRIGITHDEITNLNVARIFALFELHRIMCSEGMRSHRNKDF
                     SNYLERVNKTLELHEQNMHIKIFFNSLTKILDEFCVE"
BASE COUNT        10871 a         4563 c         6451 g         8559 t
ORIGIN      
        1 gatcgagtca ttgaaattcg ttttattgat cctagacgtt tcactgtaca gcaacgaaac
       61 ttcatctatg cgctgatagg cgatattttc atcgatacag gcatgccaac ggacttctgg
      121 aaggaattct tctacttccg tttcgaaggt gtcacagggc gcaaaataag cctcaaagat
      181 gaatcgagca caaccgtaag tgatgccaat atcttagcga atatcatcct agatttcatc
      241 tttgagcatg atattccgtt taaaaatgga tatgaaattt tgccccaaaa cgaacagtat
      301 ttcttttaca aatgcctcac gaacagggtg tgctgtagtt gcggaaagaa aaatgctgat
      361 atacatcacg tagactctgt cggcatggga aataaccgaa aaaaaataaa caattctggt
      421 aggcgcttta tggctctgtg cagagaatgc catacgaaaa ttcatgtcga aggttttact
      481 acatttacaa ctaaaagaaa gcttacggca gttgttctca aagacagtga tttaaaaaga
      541 ttggggttga atatcattga atgaattatg gatggatatc gaaggatacg agggagtata
      601 tcaagttagt agcttaggaa gagttaaatc taatcgccct aactatgtaa ttaataaggg
      661 atacgttaac aaagaaggat ttattatgaa accatctgac aatgggaaag ggtatcaaat
      721 tatcttctta agcggcaaag gttttagaga tagaaggtat gtccatcggc tagtagcttt
      781 tcacttttta aaagaagcgt atttcgaagg tgctgaagtc aatcataaga acggagataa
      841 atctaacaat actgttgaaa acctagaatg gctcagttct gatgataata aaaagcatgc
      901 tagaaaaaat ggattaacta acttgaaagg accatcaaaa ctaactgatt tgcaagcttt
      961 agctatcaag cgtttatata caaacaaatt gatgagctcc ggagaaataa tgaaactttt
     1021 taatgtcagc aggcataccg tgctgaatat agcttcaggg aagacattta gtttcttgga
     1081 agattaagag aaacacaaaa taggtgtgac taatttcaaa aataagtatc aaatcaaagg
     1141 gattaagtta aaccaggaaa caattaagaa acttagaata ggaggataaa aaatattggc
     1201 tgacaacaaa cgatactact atttaaaact aaaagagaac ttcttcgata gcgacgagat
     1261 ggttctttta gaaagtatgc cagatggata catttattct aatattcttc tcaaacttta
     1321 tttaagaagt ctgaaacatg aaggcaaact aatgtttaat gacaggattc cattcaattc
     1381 tacaatgctt gcgactatta caagacactc tgtgggagtt gtagaaaaag cagtacaaat
     1441 atttcgtgat ttacaactta ttgaggtatt agataacgga gcaatttata tgtctgatat
     1501 acaaagtttt attgggaaat cttcaactga agctgatagg aagagaaaat acagaaaaga
     1561 aattgaggaa gcaaaacaga atttaataac aagtggacaa atgtcggaca aatgtccgga
     1621 caaaactaca ccagagttag agatagagtt agagaaagat atagagttag agaaagatat
     1681 agagaatgta acgcctccga aaaaatcgaa ggctaagccc atccgtcata aatacggaga
     1741 gtataaaaat gttcttttgt cagatgagca gatggagaaa ctcaaaacag aattccctaa
     1801 tgactaccaa gagcgaatag aacggctatc tgagtattgt gaatcatcag gtaagactta
     1861 taaaaactat ttggcaacta ttcgaagttg ggcaaggaaa gaaaaaagtg agcctaagaa
     1921 tgcaagtggt gcatacaaac gcacaggacg acgagagaag cttccagaat gggcaatcga
     1981 ccaagaagcc tatcaaaaga aaaaagcgct agaacgagct aatagacaat caaaagcacc
     2041 attctaagag gtggaaaatt gaaaatcgat tatctagaac tgatcaatga aatagcaagt
     2101 tacaaaactg gtgaggaaat agagattctg agagacgttt atgaacaact tgatgaagct
     2161 ggaatcgaac gaattaagaa tgatcgttca agttggagta aactcagata ctatttcgca
     2221 ctttatatcg atgcaacaca attaagaaat ttagcttata caaaattact atttgctgat
     2281 tgcgttaaag gattgcaaaa acatcttagt gaacttgagc aggtgtaatc agatggatct
     2341 aaaaacattt acagcacaga tcgaactaat gcatcaagaa gctttaagac aaagcgcctc
     2401 gtacgaagac aagtggctca acacgttcca tggtggacgt gagagcgcac ttgatcaagt
     2461 gctcaaatta ttgaaaggag aatgtcggga tgaataagaa agcggcaatg cagcgaatta
     2521 tcgaattgac ttattcagaa gattggcaaa atgacaaaga agctgcttca gaagtgatga
     2581 gacttggaag agcgatgtgg gcagacaaga gcaacaagcc aagaccgcga aaaatcgcaa
     2641 tttggcacgg tgacaaactt ctagtgacag ggacagctga acagttagca agtctcacag
     2701 gcttgcacga gaaaatcgtg agaaaaagag ctaggtgtgg atacacagac gttaagaaga
     2761 gaacgtttag atacgtggag ggatcgtcat gacaacagaa gaagtgattc aaatgcgtat
     2821 tcgaaacatt cagcgtgaaa ttgacgatct agaacgaaca aaggcagtga tggtcaatga
     2881 aacggctaga aaggcaatcg atttgcacat agagaactta agaagggaaa ttcggagatt
     2941 ggaggaatga gcgtggataa gaaagcagca atgaaacgaa tcatcgaact gacacattct
     3001 gagaattggc aagaagacaa agaaatagtt gcagaagtcc aaaagctcgg taaatcaatg
     3061 tggactgaaa agcccaaacg gagaacgccg agaaaaattg caatctggca tgatgaccga
     3121 attttagtaa caggtactgc tgaacagtta tctgaaatta ctggattaag caaaaacatt
     3181 atctgggata gagctaggag cttatggatt gattcaaaag gacgacagtt taggtatgtg
     3241 gaggagaaaa aatgaacgaa ctaatcacaa aagtagagca gtgggctaaa gacaagggac
     3301 tggatcaagc agatccaaaa gcacagtttt tgaaagtagc tgaggaattc ggggaaatcg
     3361 cttcagcaat ggcaagaagt aatgatgagc tatttaaaga tagcgtagga gacgtaatcg
     3421 tcacgttgat tatcctttcc atgcaaaaag ggacaaacgt acaagagtgt ttagaaatgg
     3481 catacaacga aatcaaaggg cgcacaggaa aaatggtaga tggtgtattc gtgaagtcga
     3541 gtgatttgga ggacagcaaa tgataggttt aacaatattt tggtgtgcga ttggtggttt
     3601 actagcattt ctaggatact acctcatctg tgaaagtaga aaaggaagaa aatatacagt
     3661 gacaggtatt gtcctgttaa ttatcggaat tctagttgca gttggagcag aactgaatct
     3721 ttatgtaaat ggtacacaag aagatttggt gcgatttatg ttttggatga agaattagga
     3781 ggaaaaaaat gaacgaaaac aaattaatca aattaggtgt agcaggagca gtaatcgtag
     3841 gtattggagt tatcggagga tttaagttct tcgaaaaaat cgataatgga tatgtgggtg
     3901 tgcgctattc aatgaacggc ggtatcaaag atgaagcact gacgcaaggt gtgaaatttg
     3961 tagggattga caaagtgatc caatatccaa ttcgcttgca aactatccaa tcaaaaaata
     4021 tttgtcgaag acgtaacact tggtgttcca gatgtcgata aagaaacaca aaaatcaatc
     4081 gatgcgatca ttcgagctgg tcaagaaaat gaaaaagcga agctagatgc agaaactgca
     4141 aaaactcaag ctgatagtga agcttacaag aaaacaaaag ctgcagaagc agaggcagaa
     4201 tctaatcgca aagtcgccga atcagtaaca gacaatttga ttcgttatga agaagctcaa
     4261 gctcgcaaaa agcatggatg ggtaacagta aatggagcag atactgtagt tacggatgaa
     4321 gcaggcaaat aatatgggat tctttatggc taaaattctc ttgttcttag gtttagtagg
     4381 agcagcatat ctcgtgtatg cgctcctttc ccaaactgat gacaaagaag atgacaacaa
     4441 cgatgaaatg aaattttagg aggagaaata atggatctca ttacacaata cagtgatatc
     4501 atcctcaaga aaatcatggc aaagattcag aaagataaaa aagcaaaaga acgagcggaa
     4561 ttagttaagt tggaaatggc tgaaacagga gtaggagtgc gaagtagcag gcattggaaa
     4621 gcagcagcaa acattgaatt ttattacaac gaaattcaaa aagggttcga tcagatgcgt
     4681 gagctggatc ggcaaacaaa ttggagcaag aaacttcatc aagatcgttt caaatttgta
     4741 gagaagtata aagaaatatt agaagagtat ttgaggagga cagcaaatga taaaaaaact
     4801 cgttcaattc agcatggatt tatatgatat cgaatcagga gcaacactat ctgtggaatc
     4861 ggaccatcta atcataaatt ttggtggaaa gcgccagatt attttgtggg tagttgatga
     4921 tgtactgttt ccagaaattg ttcatgattt cgaagaatca aaagcggttg agtttgaaat
     4981 agtgaaaaaa gtaatggaat tgattgaaaa atacgaggag gacagcgaat gataccgaag
     5041 tttagagcgt gggataaacg aaagaacgta atgagagatg tagccgtctt gcattttact
     5101 aaaaacggca aaacaaactt tattgaatat tggataaatc ctaccgaatt gaaatcatat
     5161 cacgtgcgaa acatcgacct catgcaatcc acaggaatga aagataagaa tggtgtggat
     5221 atatttgaag gggatatagt attagtcagc gtgcgaaatg gcttcgatta cttagataat
     5281 aaagtctgta ttgtcaaaaa ttcaatagat tattccggat tagtttgtgc cactgttgat
     5341 gaagacttag agtatcaaat ttttaacaca gagctgtttg aagaatacac gtacgaagtc
     5401 accggaaata tatacgagaa tagcgagtta ttggaggaac agcgatgaat aaacaggaag
     5461 caatcaaaaa gttagaaagt attaaagcga taggaaatga tgcaatagct gcttgctata
     5521 acgagagtat aaattcaggt attacgttaa tgaaaaaaat agacgaaccg cagaaaccag
     5581 ttattccaca actcgtggcc ggttggcttg agaaatctac ggaccctttt acaaaagctg
     5641 aaaaaatagc gtatttaatc aaatctaaag atggtgattc atattatttc tgtgattggt
     5701 ttgtacgaga tggcatagtg acgcaagagc aaggagaaga attactcgct tgggcaacaa
     5761 gacaatcata tgaaacacta ttgagcctat acaacggcta cgaggttgag aaagagccgt
     5821 tatgggcaat aaagaatgcc gatggaaact atcttactaa atgtgcttta tggggaaaag
     5881 atggagtaaa ttatagtttt gaatgcaatc catctcatcg attgcttttc actgataaag
     5941 caacagcgga tgctgcagca ttgttggtga atggaacagt ggaagaggtg gtagaaagat
     6001 gaaactaaaa gacggatttt acgctagcag tcacggtatc ggcggtttaa tgctagatat
     6061 gccgacaaag aaccctaaaa cacgcaagaa atcaaaattc aaagtcggtg acatggtccg
     6121 ctgtgaagca gaagagttcg tttatccgtt cagaggatac gttaaaaaga tactgtcaaa
     6181 ctcagcaatc attcgtattg aaaatacaat gaagtgtgat cgttcgactg caaaacacaa
     6241 gcattattta gctgtagcga gattagttga catggaagta atcaagagca aataaaaaaa
     6301 gccggatcgc tccgactgat tcaataaatc caacacattt attatatcac ataaaggagc
     6361 ggtttgactt gatgcaattg ttacgagagg tagatttcaa acagacaaga tgtaatgcga
     6421 gagatgtgct gaagaacttt cggcgtttgg agcggatggc aggtcgctct ttgatagata
     6481 ttaagtcgcc gattataacg gatatgccga aggcaccgaa gcatggcaat aaggcagaag
     6541 acgcgattat tcagatgatg gatatagaaa cggagagaga tgcgattcta gcggctttga
     6601 tggctcttag tctgattagt cgtcagatac tctactacag cttctgtgtg ccagatagct
     6661 tctcaaacta cagaattagc cgtgaagtgg gttattcaga aagaagtata caacggatga
     6721 agtcggaagc tctaatagag tttgcagaag catataaaca cggaaaaata attgcttata
     6781 aataatttgg cggttttttg gcggaatgat ggcggttttt agacatttac cagtgttatt
     6841 atggtagtgt cgaaagatta ggaaacagga tcgacaaaat aaacgaaggg aggcaatctc
     6901 cctcatcgtt ttaaacttct tcttagatag acagcaacta attatgaaga aaaggatgtg
     6961 aattcaactc ctcctaaatt cttcatcggt tgctgtttat tttgattaga cagcagcact
     7021 cacaaaacta aacatgttct tgtcgtcttt caactgctgc tgtctattaa tttatgtatt
     7081 ggagggaaga aaaatgaaat tatcagtaga aggcactcca gaagaaatac aagaattgct
     7141 ccaagctatt ggtagtagca aggagcaaaa ggtaagtgtt tctaattcag atattgacgg
     7201 tatttgcaat tgtttaaaca gagaaaaaat atctaatcct tactaagaga aaatatgttc
     7261 gttaatgaat ttccaatttt cctctgtagc tctaccttga taattttttt gcagttcaca
     7321 gatgaataag gaatcgttat tatcaagtac tgtatttaat ttttcacaca tttgatttgg
     7381 attcaaatta gttttaacta accaaaaaga tttttgtagc tttatatatg ccccaaattc
     7441 ttttattatt tcaaatactt tatcatactt ttgccctggg ttattaagat cataactaat
     7501 catgtagggt ttatacatgt tgtcttgcac atccttgttt tatatttcag cggaccactc
     7561 gctgataaat aaaattatac gcttagtatt tattttcaca atattaattt atcgtaataa
     7621 cttttgagta aatagaacaa aaaacctgca ctagtttccg ctagtacagg cagtgactat
     7681 atcggttgat aatctagcat atattaaaaa taattgcaag aaaagaaatt tatagtggtt
     7741 tataccaaat tatcaaagca atgttatttt gttgctgtct attgtttttt aattattcac
     7801 acgataacta aaggtgggtg aagagaaatg attccattaa taatttcaat ttttgcgctc
     7861 tgtcttaatg tctatatgat tggatttaaa aatgggcaaa ataaaaaata gtagcagcca
     7921 agaataattt tatagtgtca ctgtggcgga aagggtagac gctaagcatg tgtgctaggt
     7981 caatgcttcg gcaaccatgc aaggttcgat tccttgccag cgacattaaa tgtctatgac
     8041 ggttacgact accgaaaaaa gatcgttaag aagctatacg gtgctacgta cggcaatgta
     8101 gtaagtgtgc tatctgtaca ccaccaagct tcggtcactg tggcggaagt agaagacgca
     8161 gcggtaaatg gcgagtagcc tcgtgagagc ctggtaagtt ctcgtgagtg gtgcaatccc
     8221 actccagcga ctttaagcaa ccgaggcatc ggcggtttaa aaatataggg gtgcgcaatt
     8281 tcgtacgcgt tttgtgcatc gtgcaagtta ctattacata ttagatcact ctttgagtgg
     8341 tctttttatt tttgcacaaa ggaggaaaca acaatgtata gaccacaata cttagaacag
     8401 aagtatgaag taatcactgt tcataaaggt aatggcgaaa aagtatatga gtatagaaga
     8461 ccaataaaga gcgatacata taaacgaaag gaaaacaatg aagttattcc attgtatggc
     8521 aaaagaatag ctaagcatta aataagattg cgaaaggaga cggaacatga ccgaggaatt
     8581 ctatagatgg ctattacagt tgacaagaga agatcgtttg gttaagttct atcagtctcc
     8641 taaatggcgc aggcttagag agaaagcgat gaaacgagat cactatgaat gccaagagtg
     8701 tagaagacta ggtaagtatc atagagtaga gaacgttcat catataaagg aagtcaagga
     8761 tagacctgac ttagctttag atttagataa tcttatttgt ttatgtgttg aacatcataa
     8821 tgaagttcat ggcagatatc ttacagcatt agataaacaa gagaagaaga tagaaagctt
     8881 tgctaacttc gatgcaagtg aaaggtggta agtgcatgat catcaatgat aatggcagag
     8941 agtatgatac agaaaagatt gaagagtatt catcttatac tcagggatta attaaacgtt
     9001 tgatatacgt tcgctatgta ggtattaggg atctgttatc agataactgt tgtagtaaat
     9061 acaaagtgaa tcaagtaaga gaagcgttga ataaagataa taacgtcgaa agaataaaaa
     9121 atgtttttgg atatagtatt gaagagatta attattacat tgacttcgct gaagctttca
     9181 ttccgatggt gagataaccc ccccttaaaa taaatcgcaa attttttggg ggtgatgaaa
     9241 cggagggggc tgtcaggaaa agagattttt tcgaacttta tcatgaaagg agggctaaaa
     9301 tgtttaaaaa cgaattgtct caaaatcgct acagagaaaa attacgccgc tctttaataa
     9361 gccaattgga aagtcagaaa acaaatattg agccattctt agataatgtt gatcgttata
     9421 tcagtttatg ggaaacggcg atatcactgg aagaagatat atccgagaac ggcattagac
     9481 tggagaatgg taaaaagaat gaatcagtag cgttgcttgt ttctgtcaac aaacaaatgg
     9541 gattgatgtt ggataaactt gccattactc ctgaattggt aggtgaagca aatgaatcaa
     9601 ttcctgagtt ataagcatat tgaaaattgg ttcaaagcta tagaagaagg cactatcaag
     9661 gtatgcaaag agcaattatt gctaaaaaat tatctagaag aaagagtctt tactagagaa
     9721 gatatttact tcgataagca gatggtagag gattcaatca atataccagc acaatacttt
     9781 ccattcgaat taattccgtg ggaaaaattt ctacaatgtt ttatttatgg tgttcgatgg
     9841 aaaaaagata aaacactagt gttcaataga tatctttcat taatgggacg tggtaatggt
     9901 aaaactggtt ttgcttcttg gaacaacttc tttctactaa ccgctaaaca cggtattaaa
     9961 aattatgata ttgatatcta tgccaataat gaaagccaag caaagactag ttttgatgat
    10021 gtatttaaag taattaaaga tcatcctgat ttagataaaa aagtatttaa agctacgaag
    10081 gaagttattc aaaatatcgc tacaaacagc aaacttcgtt ataacacggc aaatgctaga
    10141 acaaaagatg ggaagcgacc aggtgcaaac cgctttgatg aaattcacga aaatgaagat
    10201 tattcaatga taaatgtggc tacttctggt ggtggtaaaa ttcgagatta tagagaattt
    10261 tatgatacaa ctaatggtca tgttcgtggt ggtccgcttg atgacattat agaagaatca
    10321 aaaatgattc tttctggaga acttggaatt gacaaggatg gagcagaatt ttctagtttg
    10381 tttccattta tttgtcgctt ggataacgat aatgaagttg atgatcccga catgtgggaa
    10441 aaagcttgtc caactattaa ttacaatgca gatttaaaac ggaaaatgtt tcaagaatac
    10501 tctcaaatgc aacgtaatgc tggtttaaga cttacgttca tgaccaaacg aatgaacaga
    10561 cctatggaag atacacgatt tgctgttgct tcatatgatg atgttctgca tacgaaagaa
    10621 aaagaatttc ctgaaaaaat ggatgaagtg ataggaacag tcgattttgc tgatagacga
    10681 gattttgcca gcgttgggtt gctaggaaaa tacgataaag atgtttattt tacacaacat
    10741 acttttatcc acgaatcagc ccttcgatta caaaacatca aacgagaggt tatagatatt
    10801 tctatagatc aaggaaaatc acagatcgtt catggaaaaa atatagaagc tgattatatt
    10861 gtaggttggt ttcttgaaat gagtaataaa tattatatta aaaaaatcgc tatggatatg
    10921 taccgtgcaa aaatattgaa gcccgcttta gaagaagcag gttttactgt ggaaattgtt
    10981 cgaagcggat ctgttacaca tggtatgtta aaagatctgg ttgatgacct ttttattaat
    11041 caacgtttat tttttggtga cgatgcgatt atgcgttggt attgcatgaa tgtatatgaa
    11101 gagcatattt ctaatggaaa tatacgctat gaaaaaatag aacctgaaac tagaaaaacg
    11161 gatggctttt tttcattcct tcatggtttg aattttttag atgatattta tgattctgct
    11221 cctgtaacag tcacaaatag ctcagtagaa aatacaggaa ctggatttac tcctctagta
    11281 ttctaacttg aaaggaggtg agaaagtggg gatttttcaa aaggcggtag gatacttcac
    11341 aaaaaaagca acggttcctt tagaagaata cttttgtaaa ttgcaagttg attttgtgta
    11401 tcgaaaattt gcgattgaaa cttgtattga tttgattgca aatgcgatga gtaaagcgga
    11461 attcaagtca tatgaagatg gaaaaaataa aaagaatgat ctttactata ggctgaatgt
    11521 agctcctaat aagaaaaata atgcaacaga atttagaaaa aaactgatca ggagattaat
    11581 attctacaat gaagtattga tcgtttctcc gtctaataat tctagcgaaa tatttattgc
    11641 ggatagttgg gatgtcacag aatatgcatt gaaagatgat gtgttttctc aagtgcaaat
    11701 taacaacata gtccttgata gagaatttct agaaagtgat gttatctata taaaatacgc
    11761 agatcaacaa attaggcaac tagtcgatgc gtattatcaa gcgtatggga aactcatttc
    11821 tagtgccatg aatgtttaca agcgctctaa cgctcgtaga tacgtactga aagggaattt
    11881 attccgaccg caagacaata caacacaaga tcaaatcaat aaaatgatga catcacaatt
    11941 taaggctttt atggaagctg ataatgcagg tgcggtattt caattacaaa atgagtacac
    12001 attagaagat ttcagcggaa acttccaaag caattcaaga gatataaaaa acttaataga
    12061 cgacatcttt gagatgacag cagcagcgtt tcacgttccg aaaaacctac taaagggaga
    12121 catgagtggg ttatcggatc aagtggacgc ttttttaatg ttcgaaatca taccgattgc
    12181 tgaacttatt caggatgcgt ttaacgctag tctctatgaa gtagaagaat acttgtcagg
    12241 gaattttgta cgtgtggata caactatgat caagattact agcttcaaag atttggttga
    12301 cgctattgat gtaggcatta gaaatggagt atttacaatc aacgaaggaa gagaacgcgt
    12361 tggaaatgat cgctctgata aggcgatggc agatgaaata tttataacta aaaacaatca
    12421 acaagtatcg aaaggaggtg aggcgaatga cgacaatgaa aacatttcta gcagtaaaga
    12481 atgaaggcgc agtaccgcaa atttttattc agggatttat tggttctagt tggttctttg
    12541 aagggaatac tgacaaggga atcaaaaata ttttggatag tctaggtgat caagaagaaa
    12601 ttgaagtagt aattaattca aacggtggag acgtatttca agggattgct attgggaact
    12661 tacttaagtc aaataaagca aaagttaacg ttgtgattaa cggcttagcc gctagtgctg
    12721 cttcaattat cgcaatggct ggcgatacta taaaaatcta caacaatgca caattgatga
    12781 ttcaccgcgc ttccacatac ggagaaggaa atgtcgatga cttccgtacg attgctgacc
    12841 aactggaatc aattgataaa tcggtaaagg cttcatataa aacacgattc aatggcacag
    12901 atgaagcatt gcaagaactt cttgaaaaag aatcgtttat ggatgcagaa acagctttga
    12961 gttatggatt ggtcgatgaa attatcgatg cagaaaatag ctcaggtact gaagctaaaa
    13021 aagaacaaag cgttgaagaa attttgaatg acgttaaaga aaaaagagca gaaaaaattg
    13081 ctgcatttac agcagcatta aataaaacat ttggacaagg agatgcaaaa taatgacaat
    13141 taaaaattta aaaggtgtaa cagctgcaag cgaccaattg atgaaagctt ttaaagatgg
    13201 taacgaagaa tcttttagcg cagctatggt aagcttatct aaggaaattc aggataaaat
    13261 tttagaagaa gcaacagcaa aaaatcaaga tcaattagta ttaatgaacc gtggtcagcg
    13321 tgtattaact acacaagaaa caaaattcta taacgaagta gtgaaaaacg aaggttttgc
    13381 aggggtcgaa gaattagtgc cagctactgt atttgaacgt gtatttgaag atttagaaca
    13441 atctcatcca ctattgcaaa aaattacttt tgttaacaca actggtgtaa cagaatggat
    13501 tgtgtcacgt ggagtcaatc cagcatggtg gggtaaactt tgcgaagctg ttaaaaaagt
    13561 tttagataat ggctttgatg taattaacat gaagcagttc aagctatcag gttatattcc
    13621 tgtatgtaag gcaatgcttg atttaggtcc agtatggtta gatcgttatg tccgtactgt
    13681 tttagtagaa tcattgagaa ttgcattaga acaagcaatt gttgatggta ctggtaaaga
    13741 tatgccagtc ggaatgatgc gtgacatgag caaacaaact agcggagaat atgctgaaaa
    13801 aaaagcagaa cctattacag ctttagatgc tgtaactatg ggcggtttga tggcgcgact
    13861 atcaaaattc aatatcgaag gtgtgaatga tccgatttat cgtaatgtga atccttctga
    13921 tgtggtccta attgtgaatc caactgatta ctggtctaaa gtattcccag ctaagactgt
    13981 actaactgct aatggagaat acgtacaagt attgccagta ccagtttcag atttgcagtc
    14041 aacggctgtg ccagaaggaa aagcagttat tggggtagcc tcagattact tcatgggtgt
    14101 aggatctaca ctaaaaattg aagcttcaga tgaataccat tttgttgaag acgaacgcat
    14161 ttatctagct aaacaatatg caaacggtca acctaaacgt aacgatagtt tcattgtatt
    14221 agatattagc gctttgggaa ctactactac aactacaaaa ccaacaacca caacaactac
    14281 aacacaagcg taggtgatca gaatgaagta tattctttgt cagccggcaa tcaatcggtt
    14341 taaatgggag cttgaagttt gtttaactaa tctgaagaaa ctaggaatca aagatatcgt
    14401 attgcttttc agcagacacg atgatcagat tcctattttt tttgagaagg aatatggtgt
    14461 tgaagttcat gtgtacgatg atctgcggga cgacaaagag tatattcctt cgattaaacc
    14521 atatttatgg tggaaatatt tagaagaaga tcattcgcgt gaggacgacc gatatttcta
    14581 tatcgattcg gatgtcattt tcaataaaag aattaatttg cgcaaattgc cttctaaaga
    14641 tgatgtttgg tattgtagcg actgctgtag ttatctaagt cttgattata ttagaagctg
    14701 tgaaaacgga gaaaatattc taaaagatat ggcaaacatt gtaaatgtta cagtagaatc
    14761 tttggaaact ataaacacta attcaggagg cgcacagtgg gttattaacc gtcctaaagc
    14821 gaattattgg aaaaaggttt atctggattc taatcggcta tatcgctacc ttagagggca
    14881 aaaaacaaat atacaaatct ggacagccga gatgtgggca cggctttgga acatgatgta
    14941 tttcaatatt ggtcctaaag ttcacgagga attagacttt tgttttgcta ctgatccaat
    15001 agaaaaagtt aaagaagtaa aaatcttaca caatgctgga gtaacaacaa acgatgaaga
    15061 tttatttttc aaagggagat acgtgacttc tacgcctttt gatgaagatt tatcatttgt
    15121 aaacaagaaa aaatgctctt acgcatatgt taaagcaatt aaggcggtgg ttagatgacg
    15181 cctgaacaag tgactgaaga attgctaata gctgtgaagg ataatattta cgttacctgg
    15241 aacgaagaag atgagtcaat taaaaagatg atagctaaaa atgctgttta tcttcaaagt
    15301 aaagtgagta caacactttc tttttctcct gaaagcttag aatacggatt gctaatcgaa
    15361 agatgtagat acgactggaa tcgtgcttta gatgagtttg aacaaaattt cgctagtgag
    15421 ttattaggtt tcattcaaca ttatgcgcta caagaatata ttgcaggtga tgtgaatggc
    15481 gaataatcgt agactcgaag aaacattcaa cgatggttgg ttaaagattt tgacgcaaac
    15541 taccaaaaga aatgaactag gaaaaaagat tggtgtagaa gatacagaaa tcacttcttt
    15601 aaaatttaga aacctttcca tgagagatag tgatataaca gctatggatg cgatgggatc
    15661 gaaattaact aagaaagtaa agactccatt tcatccaatc gccaagaaat ttaataaaga
    15721 tcaatatttt atcgtaatcg atagtatgcg ttacaacgtt atctatgccg attacgataa
    15781 tttttatatc tatttttatc ttgaaagtgt gggtgaatat ggtgattgat aattctaaag
    15841 aaaaagaacg tttaaataag caaatttctg ctatcaaaac ttccttagaa gagcattttg
    15901 gcctcaaact ctttcaagac tccgtaggcg aggatgagct acctgatgat tttaattact
    15961 tcattctcga aacaggagaa atagaaatga tcactgagcc aaaatatagc gtgggtcaaa
    16021 atctatatct aactttctat tcagaaaata gagaagattt aacaggagac tcactagata
    16081 ttatttcatt gattcaaaat cgttcgattc gttttcagag aatggatccc aatcatttaa
    16141 aactagagaa ccaagatcgc tatatcgatc aattggtatt tacgtttaga cgattattga
    16201 agagtgattg tcatggctaa aaatagttgg gagctaaaaa taaatggaca tgatgaactt
    16261 cttgtgcgga tggaacgcta ttcaagcgag agcgaacgac tgattaacga agcattgaaa
    16321 tcaaaaggtt cggctattgc agtggatagg attacagaaa aaattcctgt ttctgaagca
    16381 gatttaagaa gagggcacca acacgcaaaa aatagtcgtc cacttaagac tcaatacatt
    16441 aatttgggtt tcatcattag acctacaaga aaatttgagt atttaaaata tcctgatttg
    16501 gggataggta cttctaaaag aaatcagccg gacgaattta tgagaagagg attaggtctt
    16561 gcacttgatc caattacaga acttctgatt cgtcaattcg ataaattaaa taaatagggg
    16621 gaacaacaat ggctaaaaca aaaactgtag taacaacgtt cgataacata agtatcaaac
    16681 gaattgcttt taattttaag aacgcaggaa atgcaatcgc aacgaattgt accggacaat
    16741 tagatggcga aacagaaatg caaacggtgg ttaaaaaatg tggagcgaca gaagtaaaat
    16801 caaaatctaa accaatcaat atgacggtaa caattactgc acatgtaccg atggaagttt
    16861 atcgacgttt caatgggttg aaacaagatg gacgtattaa accaggcatt tactcttacg
    16921 gtcctgattc cgtaggcgaa gatttctcac ttgctgcaga gatcgtggat gacttcgaag
    16981 aaaatagaaa gttagttggt atgttagcat gcacttcgaa tacaggatta acattctcta
    17041 ttgaaaatgg tgcggatgaa gtagctgcgt tagaactaga aacaaaagtt atgcaagatg
    17101 aatttggtaa attttatcat gaagcaattg ttgcagaact tgaagaagac ttaacagatc
    17161 aatggatgac gaatctatct gctgatgtga ttaaaaaaac ttcagttgtg acaactacgg
    17221 ccactcaatc acagtaaaaa aaacggaggt agcgaaatga acgaagatta ctcaaaaatt
    17281 gaactaaacg atggaacaat tttgaattta gaacctaaac tgaatatcaa gaaattattg
    17341 atgatcaata gagattttaa cacagacgag tttgcaaaaa tgtcgatggg aaaaggctct
    17401 atggatatta cagttattca aggtgcaaaa gccgtatatg tagcttatcg tcaagcgaac
    17461 atggtcgatt acatttcatt cgatgaattt atagataaat gggattttga tatggaggtt
    17521 gcagtagctg tatacagtac tatgatgttc aaacaagcac gtgatgccta tcaaaaagaa
    17581 ttcgaaaaag caaataagga aaaaaagctt caaaagtaaa aatgccaaag ctcttagttg
    17641 aaacgtgggt cgatgtctat tcgatgttga ccgacgtttt ttctatgcct tcagatttgg
    17701 ttttaagcga tatctgttta gatgacattt tgcaaatggc ttacaacaag agcgcttatg
    17761 aaggatggaa gaactatgca ataaatcaat cccagaaaaa ctaaaggaaa ggaggtaaaa
    17821 aatggctaaa aagagaacgg aagcagaagt aactttcata gctaacgatg acggattgaa
    17881 atctacgtta aaagaaatca gtgctgaatt aactaaaaat agagcagaat taaaactaga
    17941 acaagctcaa ttacaacaga ctggttctga atcagacaag ttaggaagta aattatcttc
    18001 tttagaaaag cagtatgaat tacaaagtca aaaagttgaa gtaactagtc aacgtttagc
    18061 caatgccaaa aaatattatg gagaaaattc caccgaagtt cagaaacttg aaagagaact
    18121 gattaatcaa caaacagctc agcaaaggtt atctaatgat atagataaaa cgagtaaggc
    18181 attggctcaa tctaaaggtg aatttaaaac gtatgagtca actatgaaag acttagataa
    18241 tgagcaacaa catctaaagt caagcgcatc attagtagaa tccgaatata aaaaatggca
    18301 agcaactgct ggccagtctg ctacagaatc tgaaaaatta gcaaaagcac aagaatatgt
    18361 cggcaaacag agtgatattg ctgaacaaaa aatcgaagtg ctaaaaaaac aattagatgc
    18421 cacacaaaaa gaatttggag aaacatctac cgaagcttta gaaatgaaaa ctaagcttaa
    18481 tgatgcggaa agagaattcg aagaattaag taatgctgct aaaaacgttg atacctccac
    18541 agtagatgat atcggcaaaa aacttgatat gggtaattta atggaagcta ctgatcactt
    18601 gtcagtgatc ggagataagc ttattgatgt aggtagtaag tctattgaag cagctggaaa
    18661 agcacaagct atgcaggccc aatttaaaca agtctttggc tctttagaag gggaagcaca
    18721 ggacgccgtt gagggaatgg ctgaagaatt tggaatgtta ccaaatacga tcaagcctgt
    18781 ttttacacaa tatacgtcaa tgtttaaagg acttggatat gataccaaag aagctatgga
    18841 gttagctggt gatagtactc agttagcagc agatgcagca gctttttacg ataagtctat
    18901 ggatgatgct agtgaatctc ttaattcatt tataaaaggg aactacgaag gtggggagca
    18961 aataggttta tttgctaatg atactcaaat ggcagcttat gctgttaagc ataatttgat
    19021 accagcgact gaaggagcaa aaaaagccag tgaagagtca ttgttagctg ttgaaaaagc
    19081 acaatctaag tatgctgatg ctattaagaa acatggtgaa ggatctttag aagcaagaga
    19141 ggctgcttta aaacttaaag atgcgcaaga taaaataaat gaagaattag gcccacaaac
    19201 gcaaaaatgg tctgatttag atgaggctac caagcaagca gttcgagttc aatatgctga
    19261 agatatgcaa aaattagccg gtgctacagg tcaggctagt agggagtctg atggtttaga
    19321 aaaccaaatg acaagagcaa agcaagcgtt agaagatttt tatgcctcat tgggtgaaga
    19381 tatactgcct gtgtttatca aagggttgca agcaggagcg aaagctttgc aaggattagc
    19441 cgaatggtgg agtaaacttg atgggccaat gaaaaatttc attttagctc ttggaggaat
    19501 tctagcatta ttaagcacat tagctcctgt tataaccgca gttgttacga tagttggcac
    19561 atttggttct acagttttgc tgccaataat aggaattata gcgggcgttg cagctgtaat
    19621 agcgattgta attacagcgt ttcaaaactg gggcgcaatc actgactggt ttagtgattt
    19681 atggaaaaaa tttaccgatt ggttaggtga tacctgggaa agtataaaag aaagtgcctc
    19741 atcagtttgg gatggagtca aagaaacctg gtctggattt gtagattggg ttcaagaaat
    19801 ttggcaagga gtttctgatt ggtttggaga gttatggagc ggattagttg aaggagcttc
    19861 caacatctgg caaggagtcc aagagacttg gcaagcattc gttgattggg tttcaaatat
    19921 ttggaacgga gtcaaagaag tatggtcgat tatttgggca gacattgtag gaattgttca
    19981 aataccatgg acattaataa cgtcattgat tcaagctggt attaatatta tcgtgggtat
    20041 ctttgatgta gctggacagt tattaggcgc agcttggcaa gctgtttgga cacctatttc
    20101 tgatttcctt aaaaatactt gggatactat gacacaatgg ataagcatcg cttggaatgg
    20161 aattgtaact acattccata ctatatttga tccagtagtg gcatggtgga atggtatatg
    20221 gacatctatt agtactacgg cttcaaatat ttggaactca attagtgcaa cagcttctag
    20281 tatttggaat agtatcaaga atacaatcac tagcttggta caagcagctg ctacagtaat
    20341 tcaaaatatt tggtcaactg tatctagttg gttaggtgga atttggaatt caatcagctc
    20401 tacagcatca aatatctgga gtagcgtgac tagtagtata agcaatgcta taaacgcagc
    20461 taaaagtgcc attcaaagtg tttggaatag tatatcttcg tggatcagcg gaatttggaa
    20521 cggtatcaaa aacactgctt tgaatctttg gaatggaatt acaagcacta ttagctctaa
    20581 agtaaacgat ggaaaaaatg caatttcaag cggttggtcc aatctaacag gtattgtttc
    20641 cgacatattc aataatgtta aaagcacgat agctaatata tgggaaggta tcaaaaagac
    20701 tgttagcgct ccgattgatt ggattagaga taaaatcagt agtgtctttg ataatttgaa
    20761 tatttctata ccacatattc cgttaccaca ttttaaattg agcggagaat tcaatccatt
    20821 gaaggggaaa atcccaacat tgggtgttga ttggtatgcg aaaggtagtg tgtttaattc
    20881 tccaaatatt atcggtgtcg gtgaagcagg acctgaagca gttttacctt tgaaaagatc
    20941 tgtgctgcaa gaaattgggg atcgtatctt gagtagcacc tcagtttcat ctagggcaca
    21001 aacgattcaa cctgtgaaca attacgaatt caatttcaca attgatggta acgcagatga
    21061 ggttactatg aagcaaacaa ctcaacaaat cattgatagc attacaaaag ttcaaaatga
    21121 taatgcttcg gcatggcgtt aaacaggaga gtatttctcc tgttttttta gttttaaaaa
    21181 ggatgtgaaa aaatgactga ttgtatacat tctataatcg atggatttcc tgattatttg
    21241 cataaattgg ctttagcgga aagaccaacc ataccttctc caaaaagaca gagagttgaa
    21301 acttctgttt taggacggct aggtggctta gtacaagatt actcgtttga agacatgtcg
    21361 tttacattgc actataacta tttagaagat gtggaagacc atcaagcatt caagcaatcg
    21421 ttttatatca tgcgtcattg gttaaactat gcaaagaaat tagaattctc tgatgatccc
    21481 aacgtctatt atgttatcca gactatcgat attggggatg cagaaaacga tattgttgaa
    21541 tggggagagt tcgatgtaaa tatcactgcg aaaccattcg caagagttca agaagatgta
    21601 cctataaccg tagataaacc acagtcattt aacttgctga ataatagttt agaagaaagt
    21661 tttccaaaga ttatcatcac tccttcagct acttcatgcc aattcacctt aaatgattat
    21721 gtgtttagtt ttgaaggctt agtagtggga actgacatag tcattgatag tgatttgatg
    21781 ctttgctacg aagagcaatc ggacggagat attttagatc ggtccaacaa aatgaagacc
    21841 atgcaatatc caacgttgca agtggatatt aatcatttta attgtactgg tttgagcaaa
    21901 atacaaattt atcgtaatgg gttaaggtag gtgaaataga tgatcgataa tttaataact
    21961 atttacgata aaaatgacgc gaataattta gctgaacatt tatatgatac gcaaggttta
    22021 ggcgctttgt cagactggtt aacagctact gttagcaata aactaaacgg agccgagata
    22081 tttcagggta cttattcaat aaacggaact aatgcagatt tgattgtaga aggacgtatt
    22141 attcagtgtt atgtagatga aaatcgagca aaacagcgtc tacggattta ttatgcaaaa
    22201 acttctgtaa taggcaatac gatagaagta aaagctgaac ctattttcaa tgatataaga
    22261 aaatcggtgt tgaataaata tgacagcgga acagaaaaaa tcactgctac tcaggcatgg
    22321 caaaacgcaa aagttttagc gaaaccagct atcccttcgc agttttcttt ctcgtcatta
    22381 gtagatacgc ttgctaatgt gaagatagaa aaggcgaatt ttttagaatt ctttggtgga
    22441 aaagagggat ctattctaga tcgatttcat ggtgagtttc taaaagataa taacacatta
    22501 cgtcatgaaa aaagtctagg tacggatcat aaaatcaaag cgatttatac taaaaactta
    22561 actggtcttg acttagagat tgatgctcaa agtgttttag ttggagttta tccattcatt
    22621 agcagctctt cagaaggaga agacgagatc actctaccag aagaagttat tttcacggat
    22681 tacgtggatg attatcctgc tggatatgtt tcttttgttg attttaaaga caaagcgact
    22741 gatgtagcca cattaaggga agctgctaaa gactggttga aaacaaacat agataaacaa
    22801 aaaccacaag tgagtggttc gattgaatta gtaccattga ggcatcaaag aggctatgaa
    22861 aaatttgttg atctagaaaa agtttcgatg ggtgacggag tagatgtgta tcatccacag
    22921 ttaaaagtga atatgtcagc gagaattgtg gaatatacgt ttaatgttct aaccaattca
    22981 tacgataaat tagttgtagg aaacgtcaaa acaaacttct tagaaaacac agagaataat
    23041 gtaagcaatt tgattaatga tgccattgat caattgaaaa atggtggcga aatcagtgat
    23101 ttaatcaatg atattgtaga tcatcaaact gatatgatta ctggtcaaaa tggtggttat
    23161 gttttattag atcctaaaga agcgcctagt cgtattttga ttatggacac accagataag
    23221 aataccgcaa ggaatgtttt acaaatcaac aatgctggta ttggtttttc taaaactggc
    23281 attaatggaa catatgaaac ggcatggacg ttagatggcg gattcaatgc ctcgtttatt
    23341 acggctggtg aaatagtagg aattactatt agaggtacta cattaattag tgatggtgct
    23401 gattatagaa caagtattgc taatggcaaa atgacttggt actcaaaaaa agttaacaaa
    23461 gatattatgg agctagaagc acgtgattat gtaagtgctg atgccggtat tgtatcatac
    23521 accatgaaaa ctggtggtgg tttcatgatt agaaatccac agggtaactt ggtttttagt
    23581 acgtgggata atggtaataa cagaccgttt ttatcttttg gtgcgccaaa tttcagatat
    23641 agcaatgcta gttatgtaac ttctggcgac ggtagttctt taagcattaa tggtagtgcg
    23701 ggtaactcat gggaatttaa ggtagctggt aggactatga aatttactag tgatggtatg
    23761 ctaacgttac caggttgttt ttttggttca tgggaagatg ggaaacttgc taggtttgaa
    23821 caatcaacgg tacaagtata taaagatttt actgttagag gtactaaaaa ctcaactgta
    23881 ccaacagaac attatggaca acgactattg aacgcttatg aaactccaga atattatttc
    23941 gctgattatg gggaagccgt tacaggtgac gatggtaaag ttcgtgttga tattgacccc
    24001 atgtttgctg agacagtaaa tctaagtcgg tatatgacac atgtgacacc tacagaacta
    24061 gttttgtgtg ctgttactca tgaagatatt gaccatttca tcattgaaac tagtaagcca
    24121 aacgtattag ttagatggaa tttagtggca caccgtctag ggtatgaaga tattagatta
    24181 aaagaggata cagcatatga tagcacagtg cttgaccaaa aacgttttta aaacgaagac
    24241 aaggaggtat ataaatggct agcagtttat ataatttggc tttagatttc agcaaagaat
    24301 taaactacac caaagctatt atggctcgtc aaggtgataa agggattacg gtgactgtta
    24361 aaccattttt aaatggcttg cagatggata cgagtggcgg aacatttact ttaaaaggaa
    24421 caacaccatc taaccgttat gtagatagtg ttgcaactag cgtaactagt gaagaagtca
    24481 tattttctct tgatggcaca tttatgagtg aagcaggata ttataaacac tgctacgtag
    24541 aatatagaaa aggtaatcaa attttaacaa cgcaagacat catttttttc tcactaggag
    24601 tgtctgacat ttcgcaaggc caagccgatg aatacgtttc gcaattggaa gagttgattc
    24661 gaaagtataa cgaaactttt gatgctttta tggctgaaat taaaggtaga gtggatagct
    24721 taaatcaaca gattactgat ttaactggtc aagctaaaac gctacaagac aagttagatg
    24781 ctctgaaaga agaaatttct aagttaggta acttacaagt gatgtacagt aacagcattg
    24841 atttcggggg ctatgattat tcggggaatc cgaatttgat ggctaatata aacgctgata
    24901 gcttctcgca aggtagtggt gccttatctg ttgtagatga tggtgacgag gtagtgatta
    24961 cgcttgatcc aaaccataaa ttagaggtat tcaaaccgaa aagtcaacca gccctattaa
    25021 caggcaaaac atataccgtg agtgtagaaa ttatgttaga aggcgatttc actggagacc
    25081 ctagcaagat aggcctaaga tattttaaaa tgcctaattg ggtcccagca ctaactacgc
    25141 ctaatgcatt aactgctact aagggtgtat ggcaaaaact aactgttacc gctaaaatga
    25201 ctactgcgat tgataacgct gaaagttggt atgtaacact atataataaa gacgctaata
    25261 acagcctatc cggcaaacta cgtttgagac acgctaaact cgaagaaggc tcaacagcca
    25321 caccatatca accaaattta ctcgatgcgc cgtattattt gagtaaggtg gctttgggtg
    25381 agaatttggt aacaaatgct aagttcccaa ttataacacc aaacaatcct atttctggct
    25441 ttgatatttc agaagaatta ataataggtg aaacttatac ggtatcttta aaagggacta
    25501 agccagctaa taaagaattc cacttatact acggagatgc aaattaccag cagtcgcagt
    25561 cgcagtatca ggcaacttta cttcctgtgg aaggattggc aaatgtgtgg agtgccactt
    25621 ttacagccag aaatactagt gaaacgacaa atttacttag agtagcgtta tggcaaaaac
    25681 ctaattctgc aacatatggt actgttcaaa tcgactggct caagatcgaa aaaggcaaca
    25741 cacgaactcc gaatattagt gagtataaat atcgtggtac tggtatgcgt gattcaaaca
    25801 atccaaaaga ttatgtttgg gatctagcac cagaatatgt cgaagataat ttggccacag
    25861 atattaaaat ttctgaaatc actggtaaag caaacaatta taccgatggg aaagtatcgg
    25921 agattaattc gcagttgact gcttcaatta atgaagtaga caccacagct aaggatgctc
    25981 aaacaaaagc gaatgctaat gcgactgcta tagatgaatt agacaataag atcgatgaac
    26041 gcattaatga tacagctact accacattaa cagttacaaa cgggaatacc ggatcagcaa
    26101 agctttatcg tgaaggaaaa acagtttcta tatattttgt ggctttaaac ggaaaaagca
    26161 gtggtggaaa tgattcaacg atactaacaa ttccagaagg ctatcggcca ccaattagtt
    26221 ttgagcaact ggttggctcg atagaccgtt ctactttgaa cagtgctcag ttatctattg
    26281 gtgcagatgg agccattaaa tggcgaagaa actcaagtta tggatcggat tatacctttg
    26341 caattactta cacgatttag aaaagcgtga atcgatatga aggcagcata tagaccaatt
    26401 gaaccttacg gattcgagca aatcattgtg aatgatgaag aacatttacc ggaagaatgc
    26461 acagaagtcg aaccaccgat tccaaattgg aaaccgaaat tcaattactg ggagggaaat
    26521 aaatgaaaaa catttggaaa tatggacgta ctggcggaga gtacgcagga aaagtattgg
    26581 acgacatgct tgtatccgtt ccttacacag atcagccacc gcttgaagga attcgtgctg
    26641 atggcgaacc gttaacaatc gctgatcaaa tgtttgatcc taaattgaat caatggatta
    26701 ttttagcgaa cgcactagat cacaacgatt taaacaatct caaagcaatg tatgagtcgt
    26761 tagaaaatga gaacggcgat ttaaaacaga tcaatgccaa actcatgcta agcgatgtag
    26821 caattaaaca ggaaaatact gcattgaaag aaaaagcgga tagtttagca caaatcaatt
    26881 caaaaatgat gcttgcttcg ttacaaaata gcaaagacat ttcagaaatt aaagagcaac
    26941 taaatccagc ttcaaaggga ggtgagtagt atgtttagtt ttagcgatgt gaaaatgatg
    27001 tatgattggg gctgtttcac taacgaacaa gtaatggttt tcgttccgtt gtgcattact
    27061 gaagaaaaag cagataaaat cattagcaaa gaagagagcg catcttaatt gatgtgcttt
    27121 ttattttgat tcaaggagtt gtcacatgat taatttaggg gaatggggag cgatagcagg
    27181 atcaataacc gctatcgttt ctttgatttt attagtaata aaaccaatta ctgcatcttt
    27241 ctcgaagatt actgagactc tttcaaaagt aagtcacaat ttagatttgc tgactaaaga
    27301 tttagaatcg agcaaatcag atcgattgat gattcatgaa gaactaaaga aacacgatga
    27361 aagattagat acacatgcag aaaaattggt agaacacacg caacaaatta aaactttatt
    27421 tagggagaga agaaaatgaa taataaaacg ttcgaagtac taaaatggtt cgcactggta
    27481 attattcccg cactagctac tttcgtgggg ttagttggta aagcgctcaa ttggcagtac
    27541 acagatatct gtgttgtcat cattactggt tttggcgcgt ttttagggag tgtgttgggt
    27601 gtatcaaatc gaacctacaa aatgttctcg gctgaaagcg aagaaggagg aaacaaatga
    27661 aaaagaaaat tactattact gcgatgagcc tgttaacggc tcttttttta ttacccatta
    27721 atacgtttgc ttatactatt aatgacgagt ataatttagc gccgaatcaa ggagactcca
    27781 gattagcaat tcctaacaaa attattttgc acgaaactgg aatagatgca ccagcaagaa
    27841 acgtagccgc caacatgaaa aataattata acggaagcaa ttcttatact acagatgtta
    27901 ttggtgacgg tgggattgtt taccgtgtgg gtgagcaagg atatgtttcg tggggagctg
    27961 gtaacgctaa tccttatgcg cctgtacaga ttgaattaca gcgcacatat gataaagcat
    28021 tgtttgaaaa aaactatcga gcttatattg aatatacaag agatagtgca aaaaaatatg
    28081 gaattccatt gactcttgat caaggaactt ctttatttac aaaaggaatc atttctcatt
    28141 tgtgggtgac aaattatgtt tgggggaacc acacagatcc atatggttac ttatcgcaaa
    28201 tgggagttag caaagaaaag cttgcttatg atttagctca tggatttacc gatgaaaatc
    28261 caactacttc agatgataaa ccagtcattg atccaactag agcaggtgca gcaaatccta
    28321 cgctgacaga tggaacgaat tacgcccaca ttgatcagtt tggagaaatc gaaaatgcaa
    28381 atttgcatgt agctggatgg cacattgcta attataaata cgagtatatt ttcattatgg
    28441 actacaatac tggaaaagaa ctagctagag taagagctga tgggatttat agaccagacg
    28501 taaatcaagc ttataatact ttaggaaatg ttggctatca tgtatctttc aatatgcgtg
    28561 atttccctaa taagaaagta tacgtcatga tgcgggcaac gaatgatcca gagggaaaca
    28621 ctaaaggcgg tgcgcaagat ttccatgaca aacgttggta tttaaatatt cctaaacgat
    28681 aaaaatagct cctcgttgag gagcattaca taactatatt gacaactata aaaatcattc
    28741 gataaaatag tgatgttgtc acatatcttc actatcactc ataaatagtc acactccaag
    28801 atatgcgata acaggtttgt tgccacacct tctactggtt gattgtttat ggctttatgt
    28861 ggcaacaacc tgtactctta gctcagttgg tcagagcaga cggctcataa ccgtccggtc
    28921 gtaggttcga gtcctacagg gtacataaga aatgttcaat ataaaggtct aacaaggagg
    28981 atattggttt gagcttaaaa gatgataaac ctatacttag atttaatgaa caactagaaa
    29041 agctaaatga tttaggaatc tatgtagcag ataatgaaat tcatgaagca aaaaacattt
    29101 tgagtaatca caattatttt ttcaagctat tagcttatag aaaaaattat gataaaaatg
    29161 agcaaaaaaa atataatatt tcttttttaa gtatagtaga tttggctaaa ctagatatgc
    29221 aacttcgtta tgtgttgtta ccttattgtt tggatattga acactcttta aaaacatatc
    29281 ttatgagatt aattactaat cgaaaaaata agaacggtga atatgcagaa aatggttatg
    29341 aaattgtaaa aagtgtttta gcagatgaag atactccaaa agatttgaaa gatcaaatat
    29401 ttaatggagt gagatataga gattctgacg gtaatcttgc ttttcaagaa ggatttgaaa
    29461 aatattataa tgaacctcct atctgggtag ttctagattt agcttctatt agtaaaatta
    29521 agttttttgt aaattatttg gcaaataaac agcctaataa taataatcta aaaatgatta
    29581 agaacaatat aggatacgta tcgtacatta gaaattcttg tgctcataat aaacctatat
    29641 tattgaattt acagcggaaa agcataataa aaaattctgt atatgctaat gctagacgga
    29701 ttggtattac acatgatgag attacaaatt tgaatgttgc aaggatattt gctttgtttg
    29761 aactacatag aattatgtgt tcagaaggga tgcgttcaca cagaaataaa gatttttcta
    29821 actatttaga aagagtaaat aaaactttag aactacatga acaaaatatg cacattaaga
    29881 ttttttttaa ttcattaaca aaaattcttg acgaattctg tgttgaatga tagtattaat
    29941 tcaacttatg aggtagaaac ctcgcttcgc ctccttttta ggttggtgta gtaatatgaa
    30001 aaaagaggag atattttttc tcctcttttt attatttata tagggtcata taagaatgga
    30061 taatattttt attgtagata gagggggcaa aaaaggggca aaaaactctt actagtccgt
    30121 tctagcctaa taattttaag tactatcaat gttgtttttc cttgatataa tgggattttt
    30181 gcccagtacg tacaagctaa aaacgtttgt cttgatgggc ggtatgatgt aagaaaaagc
    30241 aacttgctta tctacaactg atcattagtg aaagacagat aaaaagaggc tggaacagaa
    30301 gcgtttaact ccaagaaata agaagaaatt cacggaaatt gcttttcaaa tttttgtgaa
    30361 tttcagctta tttccgaagg agttgcttct gcttccgctg tttatacgtg tttagagcgt
    30421 gagacaaaag tgttctttac tttt
//
LOCUS       DASHWW010000025        29154 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.025, whole genome shotgun sequence.
ACCESSION   DASHWW010000025 DASHWW010000000
VERSION     DASHWW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.025"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1030)
                     /locus_tag="U2R64_001363"
     CDS             complement(<1..1030)
                     /locus_tag="U2R64_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8918189.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="U2R64_001364"
     CDS             complement(1112..1801)
                     /locus_tag="U2R64_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEM8918190.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="U2R64_001365"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="U2R64_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEM8918191.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="U2R64_001366"
     CDS             complement(2328..2831)
                     /locus_tag="U2R64_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEM8918192.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="U2R64_001367"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="U2R64_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEM8918193.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="U2R64_001368"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="U2R64_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEM8918194.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="U2R64_001369"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="U2R64_001369"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEM8918195.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="U2R64_001370"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="U2R64_001370"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEM8918196.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="U2R64_001371"
     CDS             complement(6443..7462)
                     /locus_tag="U2R64_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEM8918197.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="U2R64_001372"
     CDS             complement(7635..8540)
                     /locus_tag="U2R64_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8918198.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="U2R64_001373"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="U2R64_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEM8918199.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="U2R64_001374"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="U2R64_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEM8918200.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="U2R64_001375"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="U2R64_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEM8918201.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="U2R64_001376"
     CDS             9753..10397
                     /locus_tag="U2R64_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8918202.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="U2R64_001377"
     CDS             complement(10453..10956)
                     /locus_tag="U2R64_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEM8918203.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="U2R64_001378"
     CDS             11553..12518
                     /locus_tag="U2R64_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEM8918204.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="U2R64_001379"
     CDS             complement(12617..13789)
                     /locus_tag="U2R64_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918205.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="U2R64_001380"
     CDS             complement(13776..14921)
                     /locus_tag="U2R64_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918206.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="U2R64_001381"
     CDS             complement(14935..15867)
                     /locus_tag="U2R64_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918207.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="U2R64_001382"
     CDS             15984..17063
                     /locus_tag="U2R64_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEM8918208.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="U2R64_001383"
     CDS             17060..17689
                     /locus_tag="U2R64_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8918209.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="U2R64_001384"
     CDS             complement(17799..18026)
                     /locus_tag="U2R64_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8918210.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="U2R64_001385"
     CDS             complement(18129..20717)
                     /locus_tag="U2R64_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEM8918211.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="U2R64_001386"
     CDS             complement(20737..21396)
                     /locus_tag="U2R64_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8918212.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="U2R64_001387"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="U2R64_001387"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEM8918213.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="U2R64_001388"
     CDS             complement(22169..23035)
                     /locus_tag="U2R64_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8918214.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="U2R64_001389"
     CDS             23144..23785
                     /locus_tag="U2R64_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEM8918215.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="U2R64_001390"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="U2R64_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HEM8918216.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="U2R64_001391"
     CDS             complement(25226..26125)
                     /locus_tag="U2R64_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEM8918217.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="U2R64_001392"
     CDS             complement(26127..26924)
                     /locus_tag="U2R64_001392"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEM8918218.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="U2R64_001393"
     CDS             complement(26902..27606)
                     /locus_tag="U2R64_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEM8918219.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="U2R64_001394"
     CDS             27737..28312
                     /locus_tag="U2R64_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEM8918220.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="U2R64_001395"
     CDS             28430..29107
                     /locus_tag="U2R64_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEM8918221.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8582 a         6173 c         5242 g         9157 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa aggctctttg tcaaatgatg ttggtaaaga gaaatcttag aata
//
LOCUS       DASHWW010000026        28829 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.026, whole genome shotgun sequence.
ACCESSION   DASHWW010000026 DASHWW010000000
VERSION     DASHWW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.026"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(44..682)
                     /gene="plsY"
                     /locus_tag="U2R64_001396"
     CDS             complement(44..682)
                     /gene="plsY"
                     /locus_tag="U2R64_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEM8918222.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            809..1243
                     /locus_tag="U2R64_001397"
     CDS             809..1243
                     /locus_tag="U2R64_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEM8918223.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1409..3454
                     /gene="parE"
                     /locus_tag="U2R64_001398"
     CDS             1409..3454
                     /gene="parE"
                     /locus_tag="U2R64_001398"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEM8918224.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3466..5916
                     /gene="parC"
                     /locus_tag="U2R64_001399"
     CDS             3466..5916
                     /gene="parC"
                     /locus_tag="U2R64_001399"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEM8918225.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6193..8424
                     /gene="pflB"
                     /locus_tag="U2R64_001400"
     CDS             6193..8424
                     /gene="pflB"
                     /locus_tag="U2R64_001400"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEM8918226.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8668..9429
                     /gene="pflA"
                     /locus_tag="U2R64_001401"
     CDS             8668..9429
                     /gene="pflA"
                     /locus_tag="U2R64_001401"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEM8918227.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9514..10440
                     /locus_tag="U2R64_001402"
     CDS             9514..10440
                     /locus_tag="U2R64_001402"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEM8918228.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10622..11515
                     /locus_tag="U2R64_001403"
     CDS             10622..11515
                     /locus_tag="U2R64_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEM8918229.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11649..11774
                     /locus_tag="U2R64_001404"
     CDS             11649..11774
                     /locus_tag="U2R64_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918230.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11908..12540)
                     /locus_tag="U2R64_001405"
     CDS             complement(11908..12540)
                     /locus_tag="U2R64_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918231.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12688..13230)
                     /locus_tag="U2R64_001406"
     CDS             complement(12688..13230)
                     /locus_tag="U2R64_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HEM8918232.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13365..13754
                     /locus_tag="U2R64_001407"
     CDS             13365..13754
                     /locus_tag="U2R64_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918233.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13758..14522
                     /locus_tag="U2R64_001408"
     CDS             13758..14522
                     /locus_tag="U2R64_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8918234.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPNIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14651..15598
                     /locus_tag="U2R64_001409"
     CDS             14651..15598
                     /locus_tag="U2R64_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8918235.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15728..16468
                     /locus_tag="U2R64_001410"
     CDS             15728..16468
                     /locus_tag="U2R64_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918236.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16759..17427)
                     /locus_tag="U2R64_001411"
     CDS             complement(16759..17427)
                     /locus_tag="U2R64_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8918237.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17561..17848
                     /locus_tag="U2R64_001412"
     CDS             17561..17848
                     /locus_tag="U2R64_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918238.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18264..19802
                     /locus_tag="U2R64_001413"
     CDS             18264..19802
                     /locus_tag="U2R64_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEM8918239.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19799..20764
                     /locus_tag="U2R64_001414"
     CDS             19799..20764
                     /locus_tag="U2R64_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918240.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20751..22073
                     /locus_tag="U2R64_001415"
     CDS             20751..22073
                     /locus_tag="U2R64_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8918241.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22136..22240
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22314..23057
                     /locus_tag="U2R64_001416"
     CDS             22314..23057
                     /locus_tag="U2R64_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918242.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23072..24064
                     /locus_tag="U2R64_001417"
     CDS             23072..24064
                     /locus_tag="U2R64_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8918243.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24076..24813
                     /locus_tag="U2R64_001418"
     CDS             24076..24813
                     /locus_tag="U2R64_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918244.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24803..25525
                     /locus_tag="U2R64_001419"
     CDS             24803..25525
                     /locus_tag="U2R64_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEM8918245.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25609..26232)
                     /locus_tag="U2R64_001420"
     CDS             complement(25609..26232)
                     /locus_tag="U2R64_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8918246.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            26627..27318
                     /locus_tag="U2R64_001421"
                     /pseudo
     CDS             26627..27318
                     /locus_tag="U2R64_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            27526..27816
                     /locus_tag="U2R64_001422"
     CDS             27526..27816
                     /locus_tag="U2R64_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918247.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT        10006 a         4823 c         5950 g         8050 t
ORIGIN      
        1 gatttgtcac actcccgttt tatctctttg gaatgaaaaa gtatcaggat tttttcttgc
       61 tgctattcaa accaaacggg attcgacttt cagtatggtt tctgatacgc ttgatattgt
      121 ctttatgccg ataaaagata aaggaagaaa ctaaaaaggc aatgatcgtc agtaaccaat
      181 tgggcttagc caaaatcaca ggagctacat aaggaaggac gatcgtagat aaagtgatca
      241 atactgcact gatcatactg ctcaaactca ccatacttgt acaaaataaa ctaacgataa
      301 agatgataca agaataaaca aaaaatacag gattaaatcc taaaagcatt cctgcacttg
      361 tcgcaacagc ttttcctcct ttgaacccag caaaaatcgg aaatgtatgg ccaagaatgg
      421 cgcatacccc aaaccaaaga gggttaatcc cagaaaggtg gaagatcatc ggcaaacaag
      481 tagccaatgt accttttaaa atatccataa gcaggacaac aatcccggct gttttgccta
      541 atacacgaaa tgtattggtc gttccagtat taccgctccc gtgttgtcgg atatcttttt
      601 tgaaaaacaa tttgccaatc cagacaccgg aaggaataga acctaaaaga tatgctaaaa
      661 taagtaataa gatcaatttc attttttacc ctctttcaag ttgaaaacta tcctttattt
      721 tagcatgaat aggtaacagg aacaattgaa aaaatgaaag atacaagtat aatagatgga
      781 ataaaaagaa aagcaagggg tggcagaaat gtctgtaaaa aatccaacac aagaaacgat
      841 tttcaactat ttggaagaag caaaaaatat tgccgtcgta ggcttgagca ataaaccaga
      901 acgaacaagt tacatggttg cacaggtatt gcaagacaat ggatataaaa tcataccagt
      961 aaatccatta ttggctggtg aagaaattct aggcgagaaa gtctatgcga atttgacaga
     1021 aatcgatgat ccaatcgata tcgtagatgt atttagacgg agtgaatttt tacctgaaat
     1081 agcaggtgat tttttgaaaa ctgatgctaa agtgttctgg gcacaattag ggattgaaaa
     1141 caaagaagca gctgagatgc taagaaaagc aggacgtaca gatatcgtaa tggatcgttg
     1201 tattaagatt gaacttggta agttgaaaga aaaccaaaaa taaaaatgac cacaaagaag
     1261 agatgatcga tagaggggaa tgtcgaaaaa gcggttagga gataattaaa attgatttct
     1321 cgtctaccct cttttttttc acgacctttt ctagtatgat aatcgtggtg cggttttgcc
     1381 gcaaagtatt attgaaggag cgtttgcctt ggcaaaaaaa gtaaacaacg aatacaatga
     1441 ctcgtccatc caagtattgg aaggattaga ggcagttaga aaaagaccag ggatgtacat
     1501 tggatccact gacagccgag gcttgcatca tttagtctat gaaatcgtcg ataatgcagt
     1561 tgacgaagca ttatcaggtt atggcagtga gattgatgtg accatccatg aagacaatag
     1621 tataactgtt gcagatagcg gacgtgggat gcctgtagga atgcatgctt ccggaatacc
     1681 aacagttgaa gtgattttta ctgtgctgca tgctggcgga aagtttggtc aaggagggta
     1741 caaaacttct ggtggactgc acggtgtagg agccagtgtg gtaaatgcct tatcgaaatg
     1801 gctaattgta acgatcgtta gagatggcgt agagtatcag cagaaattta aaaacggcgg
     1861 taaacctgac ggtactttga aaaagatagg aaaaacaaaa aaagcaaacg ggacgactgt
     1921 ccatttttta ccagatgata caatattcag tacaacgaaa ttttcatatg aaattttagc
     1981 cgaacggtta agagaatctg cctttcttct aaaaggcgtt aaaatctctc tttctgatct
     2041 tcgtggagaa gaaccagtca aggaaatttt tcattacgaa gaaggaatca aagaatttgt
     2101 tgattatctg aatgaagaaa aagatacatt gacaccagtt gtttattttt caggagaaaa
     2161 agaaggtatc gaagtagagg tcgcttatca atacaatgac ggttattcag aaaatgtttt
     2221 atcttttgtc aataacgttc ggacaaaaga tgggggaacc catgaagctg gtatgaaagc
     2281 ggcgatgacg aaatcttata atgaatatgc gagaaaagtt ggtttgctga aagaacggga
     2341 caagaatctg gaaggtagtg atttcagaga agggttagct gctgtacttt ctatccgtgt
     2401 acctgaaaat cttctgcaat ttgaagggca aacaaaagaa aaacttggta cgccagttgc
     2461 tcgtaccgta gtagataacg tcatcagtga acaaatgggc ttttatttgc aggaaaatag
     2521 cgaaatgagc cagatgttgg tccgtaaagc aatcaaagcc agagaagcga gagaagcagc
     2581 acgtaaagcc agagaagaaa gccgaaatgg gaagaagcgt aaaaaaggcg aatctcttct
     2641 ttcaggaaaa ttgacacccg cacaatcccg aaaccctaag aaaaatgaat tgtatttagt
     2701 cgaaggggat tctgctggcg gatctgctaa acaaggaaga gacagaaagt tccaagcaat
     2761 tctaccttta cgaggaaaag tcatcaatac cgaaaaagct aaaatgcaag atatcttgaa
     2821 aaatgaagaa atcaatacga tgatctatac gattggtgca ggagtcggtc ctgagttttc
     2881 tatcgaagac tgtaattacg acaaagtaat catcatgacc gatgcggata cagacggcgc
     2941 ccatattcaa gtattactgc ttactttctt ttatcgttat atgaaaccgc tgattgaagc
     3001 tgggaaagta tatatcgcgt taccgccttt atataaagta tccaaaggac aaggaaagaa
     3061 gcaagtcatt gaatatgcgt ggacagatga cgaattggca gcaatgatta aaaaagtcgg
     3121 caaaggatat atgctgcagc gatataaagg acttggagag atgaatgcgg aacaattgtg
     3181 ggaaacaacg atggatccga cttcccgtac gttgatccgc gtccgtatcg atgatgctgc
     3241 gcaagctgaa cgtcgagtaa ccacactgat gggtgacaaa gtagaacctc gaagaaaatg
     3301 gatcgaaaat cacgtgcaat ttacgctcga agaagatggc agtatcttag ataaaaaaga
     3361 ggatactgaa atctctcctt cagtttctaa tgatttatta gatgaagaac gagcagataa
     3421 aaatgaaaac aatcagttat ttgaagtaga ataggaggtc acctgatgga aaatcgacaa
     3481 gaagtacaag aattaacttt agaagaagtg atgggtgacc gcttcggacg ttattccaaa
     3541 tatattatcc aagaacgtgc actgcctgat atccgtgatg gattgaagcc agtgcaacgc
     3601 cggatattat ttgccatgaa caaagatggc aatacgtatg acaaaggatt ccgtaaatca
     3661 gcaaaatctg tcggaaatat catggggaat tatcatcctc atggtgaccg cagtatttat
     3721 gaagcgatgg tccgcatgag ccaagactgg aagttgcggg aagtactgat cgaaatgcac
     3781 gggaataacg ggagtatgga cggtgatcca cctgctgcga tgcgttatac tgaagccaga
     3841 ttatccaagt taagtggaga gatgctagca gatatcgaga aagaaacagt cgatctcgtg
     3901 tggaattttg atgatacaga aaaagaacca acagtccttc cagctcgata cccaaacctt
     3961 ctcgtcaatg gatcgacagg tatatctgct ggatatgcaa cagaaatccc gactcataac
     4021 ttagctgaag tgatcgatgg cacaatctat atgatcgatc atccacaagc gagccttgaa
     4081 aaattgatgg aatatattcc tggacctgac tttccaacag gagggatctt gcaaggaaaa
     4141 gatgaaatca aaaaagctta tgaaacagga cgaggaaaag ttattcttcg ttcgaaaaca
     4201 aagatagagg caatgaaggg taataaacag caaatcgtga tcacagaaat cccatatgaa
     4261 gtaaataaag cgaccttggt gaaaaaaatg gatgagatcc gtttgaataa gaaaatcgat
     4321 ggaatagctg aagtacgaga tgaaagtgat agaacaggtc tgcaaattgt cgtcgaattg
     4381 aaaaaagacg ccaatgctca aggaattttg aattatttgt tcaaaaacac tgagctacag
     4441 atcaattaca atttcaatat ggtcgctatc gaccatatga ctccgcatca agttggactg
     4501 aaagacattt taagaagtta tatcgagcat cgaaagcaag tcataacaaa acgtagtcaa
     4561 ttcgatttag ccaaagctca aaaaagacag catatcgtag aaggattgat gaaagcttta
     4621 tcgattctgg atgaagtaat cgcaacgatt cgtgaaagta aagacaaaaa agacgccaaa
     4681 aagaatttag tcgacgtctt tcaatttaca gaagaacaag cagaagcaat tgtcacattg
     4741 caattatacc gtttgacgaa cacggatatc acagagcttc aaaaggaatc cgaaagcttg
     4801 attgcgcaaa tcacagagtt gaataaaatc ctttcaaatg acaaagagct tttctctgtt
     4861 atgaaaaaag aattgcgaga agtgaaaaaa aattattctt ccgctcgtct aacgacaatc
     4921 gaagacgaaa tcgaagaaat caaaattgat acgcaagtct tagtggcaca agaagacgta
     4981 attgtcagtg tgacgcgaga aggctatgtg aagcgaacaa gccttcgttc ttatagtgct
     5041 tccaaaccag aagaaatcgg gatgcgagaa ggcgactact tgctatactc aggtgaattg
     5101 agtacattgg accatgttct tctgatcaca aataaagcaa atgtgatcta ccgccctgtc
     5161 catgaactac ccgatttgaa atggaaagat gctggtgagc acatttctca aacaatctcc
     5221 aatctgtctg tagacgaatc gattttagct gttttcccat atcaaaaaat tcaagcagag
     5281 aaaacatttg tattcatcag caagaatgga ttgatcaagc aaacacgaat gacagagttc
     5341 gaaccatggc gcacctataa gagccgtccg ctcagctgta tgaagctaaa ggcggaagaa
     5401 gatgaactga ttgctgtgta tctgaaagaa gatcagccag gcttagatgt tttcttagta
     5461 acgcatcaag gaatgggttt gcgctatcct ttaacagatg ttcccgttgt tggagcaaag
     5521 gcagctggag tgaagtctat gaatttgaaa gatggagata ggattatcaa cgggctgctt
     5581 gtgttagcag aaggtgatac gccgatcgta atcgttactc agcgaggagc tgttaaacgc
     5641 atgcttgctc aagaaatcag ccaaacttca cgtgcgaagc ggggagtgac ggtcatgcgt
     5701 gagctgaaaa aaaatccgca ccgtattatc tatatgtcgg aaggaagatc aaaagaaata
     5761 accttgatga atcaaaaagg gcagcagtta acgattgacc caactgattt ccctataggt
     5821 gatcgaacat cgaatggatc atttgcgatg gatgagaaaa aaggtggaga agtcatcgaa
     5881 gttatcgatg ctcctgagat tttcatcgag tcgtaactgt tgtagtattt taatgaagag
     5941 acgccatctg tattaataca ggtggcgtct ctttttcatt catttttaat aaatccttat
     6001 acgtttgcaa aaaaagatga aagtgttcac aatgcttaaa tgttggtatg tcaacgttga
     6061 tttaaatata tgtaaataaa acataaaaat tgttaaataa aaaacaagaa aacccttgca
     6121 aagatagggt gctgtgttat actaatcacg taaaaactgt tacataaaac agaaatttag
     6181 gaggtccata caatggagca atggaatgga tttaaaggta ccaaatggaa agaaggcgta
     6241 gacactagag actttattca aaataactac actgaatatc gcggtgatga cagctttttg
     6301 gaaggcccaa cagaagcaac agaaaaatta tgggatgaat tgcaaaagtt aaatgatatc
     6361 caattcgagc gtaacggtgt ctatgatatg gacacagaaa tcgtatcaac tattacttca
     6421 cacgatgcag gctatttgga taaagatttg gaaaaaatcg tcggtctaca gacagacaaa
     6481 cctttgaaac aagcattcat gccgttcggc ggaatcaata tggctaacaa tgcgctaaaa
     6541 agcaatggct atacaccaaa cgatgaattg acacatattt tcactgactg gcgcaaaaca
     6601 cataatcaag gtgtatttga cgcttatact gctgaaatgc gtgctgctcg taaaaacaaa
     6661 atcattacag ggcttccaga cgcttacggt cgcggacgta tcatcggtga ctatcgtcgt
     6721 gtggcattgt atggaatcga ctatttgatg gaacaaaaga aaaaagatca tgatatgact
     6781 ggttatcata caatgagtga agaagtgatt cgtttacgtg aagaaatcac tgaacaatat
     6841 cgtgcattag cgcaaatgaa agaaatggct gcgaaatatg gctatgatat ttctaaacca
     6901 gctgcaaatg caaaagaagc tgtccaatgg ctatacttcg gatatttagc agcaatcaaa
     6961 tcacaaaatg gtgctgcgat gtcaatcgga cgtatctcag cattccttga tatctatatc
     7021 caacgtgatt tggataatgg agtaatcaca gaaaaagaag cacaagaatt gatcgaccac
     7081 ttagtaatga aattacgtat ggtcaaattc gcgcgtacac ctgaatataa ccaattattc
     7141 tcaggattcc ctatctgggc tactttatcc attgcaggta tgggattaga tggtcgttca
     7201 ttagttacaa agaatgattt ccgtctgctt catacattaa caaatatggg accttcacca
     7261 gaaccaaact tgactgtttt gtattctgaa caccttccag aaggattcag aacatatgct
     7321 agcagaatcg ctatcgaaag ttcttcgatt caattcgaaa atgataatca gcttcgtgaa
     7381 caatggggtt ctgatgattg tgcgattgct tgctgtgtat caggaacagt tgtcggaaaa
     7441 gacatgcaat tctttggcgc tcgtgctaac ttggctaaaa cactattata tgccatcaat
     7501 ggcggagtcg atgaagtgac tggcgcccaa gttggaccag aatatcgtcc aatcacatca
     7561 gaaatactag actttgaaga agtgaaacat aacttcatga atatgatgga ttggttagca
     7621 gaactatatg tcaatacgtt gaacatcatt cattatatgc atgataaata ttcttatgaa
     7681 gcagctcagc tggctttgat ggattctgac ttgcaacgca catttgctac aggtattgct
     7741 gggatctctc atgcggcaga cagcttgtca gcgatcaaat atgcaaaagt aaaagcaatc
     7801 cgtaatgaaa aaggaatagc agttgatttt gaagtggatg gcgacttccc taaatacgga
     7861 aatgatgatg accgtgcaga tgaattagtt tcatggatct tggaatactt catgggacaa
     7921 atcaaacgtc ataaaactta ccgcaactca aaaccaacaa cttcattatt gacgattact
     7981 tcaaatgttg tttacggtaa aaatacagga aatactcctg atggccgtga agctggaaaa
     8041 ccacttgcgc caggagcaaa tccaagttac aatgcggaac aaagtgggtt attagctagc
     8101 ctgaactcaa cagctaaaat gaattacggc tgtgcattgg atggaatttc aaatacccaa
     8161 acaatcaatc cttcaggtct tggaaaagaa caagatacaa gaatcgaaaa cttgcgtaat
     8221 gtcttagatg gatacttctc aaaaggagct tatcatttga atgtcaatgt attcagtaat
     8281 gatttattgc gtgatgcaat ggaaaatcca atgaaatatc cgaacttgac gatccgggta
     8341 tctggttatg cagttaaatt ccgtgacttg acaagagaac aacaattaga tgtcttgatg
     8401 agaacttcac acgacagaat gtaaaaagtt cgtgaaaaaa gtttttcgac ttagcgtcga
     8461 aaggacgttg aatagccatc gcatcaaaat cgaataatca gtatgcttat ttgaaagaaa
     8521 cgatttacag gggcaggact tgtatgttcc gtccctgtaa attttacaca taacgaagcg
     8581 gcaattgcga aaaattttgt tcagaaagct tcgcttcgac agctaacttg tacttaaaat
     8641 gaaatcaaag aaaagatgtg aacttaaatg gaagaaaaaa caatcggcta tgttcattct
     8701 atcgaaactt tcggttcagt agacggacct ggactgcgct ttgtcgtgtt tatgcaagga
     8761 tgccgcatgc gttgccaatt ttgtcacaat ccagatactt ggaatattgg cggagggaaa
     8821 gaatacacag cagatgaact tttagataaa gcagaacgct tcagacctta ctggggagat
     8881 aaaggtggta ttactgttag tggtggagaa cctctattgc agatcgattt tttgatcgaa
     8941 ctatttaaaa aagcaaaaga gcggaagatg catactacat tggatacatg cggaaaacct
     9001 tttacgtatg aagaaccttt cttttcacgt tttcaagaat tgatgaagta tacagattta
     9061 ctgttatttg acatcaaaca catcgataat gaagagcata aaaaactaac gcattgggac
     9121 aatgaaaata ttttagaaat ggctcaatat ttgtcaaaaa tcaacaaacc ggtttggatt
     9181 cgccatgtac tagttcctga gcgaagtgat tatgatgaat atttgatccg actagacaac
     9241 tttattcaaa ccttgtcaaa tgtagacaga gtagagattc ttccttatca tacgatggga
     9301 aaatacaagt gggaaacact tggtttgaaa tatccattag aagggatcga accacctaca
     9361 aaagaacgtg tcgaaaatgc taaacgattg cttcatacag aagagtatac aaaatattta
     9421 acgcgatagg tcgcatcgga aagaagataa gtattgcttc tttccgtttt tttgctatta
     9481 ttaaatagga gaaatcacaa aggagcgaat gacatgtcaa aaattttagt ttttggtcac
     9541 caaaatccag atacagatgc aatcggggca gccattgcgt tttcacactt gcaaaatgaa
     9601 ttaggtaaag aaacagaagc agttgctcta ggtacaccta atgaagaaac acaatacgca
     9661 ttagaccact ttcagctatc tgcaccacga gtagtagagt cagctaaagc agaaaatgca
     9721 gatgtcatgc ttgtggatca taatgaattc caacaaagta tttcagatat cagcgaagta
     9781 aatattttag ctgtagtaga ccaccatcgt attgcaaact ttgaaacagc taatccattg
     9841 tactatcgtg cagaaccagt tggatgtaca agtacgatta ttttaaaact atataaagaa
     9901 aaccaagtaa caattcctaa agaaatcgca ggaatcatgc tctcagctat catttcagat
     9961 acattgttgt tcaaatcacc aacatgtacg cctgaagatg aagcagctgc aaaagaactt
    10021 gcagcaatcg ctgaagtcga tctaaacact tatggacttg aaatgttgaa agcaggaaca
    10081 aatctaagtg ataaatcagc tgcggttctt cttgatttgg atgcaaaaag tttcccaatg
    10141 ggcagttcca acgttcgtat cgctcaagtc aatacagtgg accttaatga agtgatggat
    10201 cgacaagcag agctagaagc agcaatggaa gatgaaatga aagcaaatgg ctacgatctg
    10261 ttcgtattag ttgtcacaaa catcttagac agtgattcag aattacttgt tgctggtaaa
    10321 ggaaaagaaa aagtagaaga agctttccaa acaactttga ccaacaaccg tgctttgctt
    10381 aaaggtgtcg tttcacgtaa aaaacaagtc gtacctcaat tgacggctgt atttagctaa
    10441 tcaaatggta gtatgaagca ttcaaaatga atggataagc gattgatata aaaagaaaca
    10501 tagaacatac taaaggccga agaaatggag gagaataaca gtcaattatg actcttgttc
    10561 ttcctccttt ttacgtaaaa gccttttaag taaaataaaa cggatagaaa agagaacata
    10621 tatgaactat tattcaaaaa ataaggaaaa cttttatcaa aaactgaccg atgatccgct
    10681 tttttcttca ttgaccgatt atctatatga acatcgagaa caagaaacga ttctaagaga
    10741 attgaaaaaa gaattttcgc aaaataaatt ttcccatttt cttgatttat tgatcgatgc
    10801 aggattaatc aagagggaag aacgaagata tcatttgaac tttccaatat ttgatcctaa
    10861 agattacttg caacaagcca cttcggctgc tgaaaccata gctgaacaat tgaagagact
    10921 ctctgttgat gaacaaaaat tagcgatggg agaagttatt tgggcgtatt gtttcgaaga
    10981 tgaacggaaa gaagcgtatt tttatggagt aagaaacagc cgagagacag aattgctgag
    11041 gacaactgca ggaaatgaga agtaccgttt tatcacactt tcctctatag aacacttccc
    11101 gcttactttg gctaattact tttttgtaca gaagaatcag cttcctgtaa cgaaggcatt
    11161 caaagaatta gccgaactta ttggagacgt aaatgaatcg tacttttttg atcaaataga
    11221 agttatcgtt gacaggatac gtaagaataa atataaaaat cgccggccta gtattttcca
    11281 tcagtctcta cttgtgacga atactataaa ggaagaagaa tcattcacat tagaattacc
    11341 tattgtcgaa aaaaacaatt ttgagattga attaccaaca ttggatcctt cattgacaat
    11401 ggaggaaatg gcctttctta aacgacaaat cttttctgag ctgagcaaga aatttatacc
    11461 gcatgcattt tcttatatca aagaatatgg aacagtttta gtgagtaaaa cctaagagag
    11521 cagtaagcaa aaattatact gactcttgca ggaggagcct ttctcttcct ttatggttaa
    11581 aagaattatt tgagtatttt gcctatctac cacctattag attcactaca tggtctggaa
    11641 acaaaggaat gcaaaaaaat ggtgagaaat gtggaatgac aaaggaagta gtgataagaa
    11701 aagttagatt tttaaataat caatattatg attcagtcaa gtatggcatt ttatgggaag
    11761 aactagctga ttagattagg aagtccattt gataatccag aatcactaag aaacgaatgg
    11821 cgagtcatta ataatttatc caatcttggg ttattctttt agattgaagt gtttaaaact
    11881 aaaaaagcat ttatgaagtc gtaatagtca ggcttcaaaa tgctttttat tttgtttgtt
    11941 ttttctttgc cacataaata cacctagact gacgatgaag agcatatcca acagatttcc
    12001 tgcgacttgg atcgtcgaag ggttggtcag tggcattaaa gcaaggacaa aaaaggaaaa
    12061 caagctgtaa ataaaacagg tgacaggaac taatcgaaag aagagcggac atttcaattg
    12121 gctaaaaatg agtgaaaaaa taaaataagt aaaaatggat aaaatcacga ctaaaccatt
    12181 catgataaag aagaaaagcg tattgtgatt aaacgaataa aaaagaattg ctaaaaaaga
    12241 aaacgtttta aatgcaatca atacgcttga agcttcgttt aacgtaccag gatgtcgatg
    12301 aaaaaaatag gcaccgaaat aaacagaaaa cagtaagccg caaagagaag acaaaatcaa
    12361 aaaaaacgga ttttcttcgg cttctgtgat atcagaatga tccaaaagca accagcctaa
    12421 tgcactagaa ggcgcatgtg aggtcttaag gtatgaataa catagaaaaa ataagatcgt
    12481 caaagttgca aaaaaagagc ctaaatgtaa aaaattagtg gttctacgtt gaatttccat
    12541 aatatctcca aattaaattg ataagtatat aaagtataat aacaaattga tgagtatatg
    12601 tcgatgtttt ttaatcaaaa taataaataa aaactgtcta acatttaaaa tttaatttag
    12661 atattagaca gtttttaagt ttgtgagtta ttttccttgt cgttttctca cttttttagt
    12721 ccagaaacca cctgaaatat attttggctc ataagaaatg ataaaagcac gctcttcgat
    12781 ttctttgatc aggcgataca gttcacgttc gctttttcta ggagaaagta tttcgagaac
    12841 tagccgctca ccttccagcc ccattgcaga agtctgtgtc acaccataac cgtgttctct
    12901 cagtataccc ggcaaacttt tatcttctgc gctatttgct ggcaaaatcg ttgtgaccat
    12961 gatgtatcct aatgccaatt tgtcttcaat caaaattccg acactgatac ctactgcgta
    13021 acctaacgca tagacaaata aattcagtgg attatctaaa cgatctaaaa caagggataa
    13081 gccgacgata taaatcgtga tctcgaccat actgacaagt ggagcaatca gtcgatagcc
    13141 tttcattgtc aacatgaaac gtaacgtgtt cagagtgata taagcaaaat taatgaggaa
    13201 gatcatcccc aacatttttg gatcaatcat ttgtaaaact cctttcattt atataacaac
    13261 aatatcaaaa aaaatcgtaa gtgaagaaaa attgaaactt tatacataca aaaaaatgat
    13321 aaaatgatta taatagaatt ataaagatag gttaggtgat taaaatgaaa acggtcaatc
    13381 gtgtgttttg tgccagccac gtgctaagtc tccttctcag tatatactta ggtgtctatt
    13441 cgattcaaca gccaattgag gtagagaaca ttgtttttca gatgtcgctg acagatggtt
    13501 taattttaag cgtttttttc tttttgatac tgtttattgg taatattttc ggtagcgttg
    13561 ccagtttttt gaatttttct atttatccac tcctttcgct agcattagga gtggtgggac
    13621 tttgttctct gtgcttattt cccgagccat tcagtcctgc atttatatta tttggtacac
    13681 tgaacctgtt ccagacaact gttggagcat ggttgctatg gcgatcagga aatttaatga
    13741 aaataggtga gtaacaattg aatccaatta tattgaaacg ttctgtccat catattccag
    13801 tgttagaagt tgttctgaaa gaattaagag aggaacgtat tcccgttgtc atctattatc
    13861 acggatggca gacaagtaag gagttagttt tgacgcaagg aagaaaaatt gcgcagcagg
    13921 gcattcgtgt gatcctgcca gatgcgatga atcatgggga gcgcaaacag ccggtttctt
    13981 ctattccatc ctatacattt tgggatagta tctacggaaa tctgtttgaa tttgacacac
    14041 ttatcaagca tttagaaaaa agaggtcttc tacatgatca gcttgcagtt ggcggggttt
    14101 cgatgggggg aatgacaaca tgcgccttgt tggctaaaca tcctaatata gtagcgggcg
    14161 tgtgtttgat gggttcccct gcacctttgg aatatggaaa agaaatcgta aggcgcgcat
    14221 cggaatataa ttatgtcgta ccaaaagact attttgattt gatttcatgg gttaagagct
    14281 atgatttgtc attgcagccg gaaaagttag ctggacgtcc tctgttcttt tggcatggac
    14341 aagctgacga aaaaatccct tatatacaaa cggaacgatt tgtagaaaaa aatcggcata
    14401 agtcttacgg aaaagaaatt gtttttcgtt cctcaaaaac acagcgacat atggtacaaa
    14461 taccactaat ggaagaagct tccacttttt tagcaaaaaa tttgataaaa aagtataaat
    14521 aattgaaacg gaaaatcact catgacgata gaggattttc cgttttttat tttgggctat
    14581 aataaactct gttaggaaaa tttggtataa ttgatagtaa gaatgacaac atgttagaaa
    14641 ggaagagagc atgcccactt tagcagatgt tgcaaaacgt gccaatgttt caaaaatgac
    14701 ggtctctcga gtcatcaatc atccggaaca ggtgactgac gaattgaaag agttagtttt
    14761 ctcagcaatg gctgaactgg attaccgtcc aaatattgct gcaaaagcac ttgtcacgaa
    14821 tcggtcgcag atcatcaaat tatttatact ggaagaaatc gacacaactg agccctatta
    14881 catgaatttg ctgatgggaa tcgctaaacg gatcggtaaa gcgcattatt ctctccaatt
    14941 agttacaaat gatgccttcg acgtcggttc ttgtgatgga tacatcatca caggtgtcag
    15001 aaaaaaagac ttcgattgga tcgaccgttt ggaaaaacca gttgtcttgt ttggggaaaa
    15061 ttctgaagga tatgattatg tagacagcga taatgaatat ggtacagcaa aagcaacgca
    15121 atatgcctta gaaagagatt atcaaacgat tatttatatc ggtatcgaag tggacgagcc
    15181 ttttgaaatt tcaagggaaa ctggttattt atctgtgatg aaggaagttg atcttcctag
    15241 taaaatcttg cggtttccaa atcattcgac agaagtagaa agatatatga cagaaaactg
    15301 ggcagatttt acagataaaa cttgttttgt atgtagttca gatcggctag cactaggagc
    15361 agtaagaggg attataaatg ctggaggaca cttgcccgaa gaatttggtg tgattggatt
    15421 tgatggggta tttttagacc aaatcagttc acctaaattg acaacgatca agcaagatat
    15481 tatacgtatg ggtgaagtat gtggagaaat gttgttaaaa aaaatagaag aaaaaggggc
    15541 gagtcaaggt tatcgtcgtt tttttcctga actagttatc agagagacaa cgaattaagt
    15601 cttattacta tatatatatt tatgaaattc atcgctattt tcttaaaata atcagcgcat
    15661 tgctactgaa aacaatgaat ctgtgctatt attgagaaaa gttccatttt tgagaaggat
    15721 ggtttgaatg aaagaaatca gacgaaaaca tttccgtttt cctgcgtacg atgatgagtt
    15781 aggcgtaaaa ttaaccaacg acaagaagcg agtattattt gacggacaag aagatctttt
    15841 gactgaacag aatcagtccc cgtttgaaca gatgaaagaa tttcatttca cgaacacgaa
    15901 caccgagaaa atccgtcgca agcgtcgtgc aacaaatgga ttgaagtcag ctccgcgtaa
    15961 ggaaaatttg gaaaagcata aaggaaaatt accggattat accggccatt accaatcaga
    16021 aatcacatcg acaggacgaa aaaaactttt tggtgattcc tctcgttctg tcagacaaag
    16081 tgaaacaagg acagagtcca agcatactac acgaaacgca tctgttgaca cgaaggtgcg
    16141 ggagcgttct tattttgttc ctaaatatgt acccgcatcg attatcccag accctagaga
    16201 aagcaaaatt tctgaggatc atttaatcga atcgatgaaa aaaacggatg actcttatct
    16261 gttgttcgat acagaaccga cgccgtatca agaaaaaaga aatggtgagc cgtctgtacg
    16321 aacattcaat cgaacaaaaa cgttagagga aacaaagcag tcagaagaaa aaaaatcgaa
    16381 aaaaagccat ggtatcttag aacgctcatt acaaggattg atcgatgatc aaggaaactc
    16441 tttgggagaa aatagctatt ttaaataagt gatatacaaa tttatattcg gctacagttg
    16501 gaaaggaaac gctgcggcgt ttccttattt tatactctat ccgaaagttt atatcgtatc
    16561 ctcaaatttt tttgagttta agcgaatttt ttctcccaat aagtaagaaa ataatggcaa
    16621 aataaaaaaa caaactattt tcgcagatcg tttgcaaaaa tagtttattt ttttataaag
    16681 aagattttac tgaataatat cattttagtt tacataatga tatttctgta aattaaataa
    16741 agtagtgaaa aataagaatc agtgctctaa ctgttcaaga ggatcaagtg gttcaaatgt
    16801 ttctgtagtc tgttttgctt ccaattgggg caaaacagat ccaatttcca gatacttcac
    16861 tttattcaat gtataagata gaatagaaca gctaagtaat gtatacagaa aatgtgtgag
    16921 atccaaataa agcaaggaga caactaaaat accaaaagta atcaagaaaa gacttttgcc
    16981 aatcttaata tgaaaatatt tttcaatggc ttgataaatg atatctgttc cgcctgtgct
    17041 tccgccgaat cgaaagacga gaccgcaacc aatgccagaa agaatacctg tcatcaaact
    17101 attgatcagt agactatcta cagcaaaatg tatatgaagg ctctcccata aatgtaaaaa
    17161 gaaaactagc gcaaatgttc cgacgatcgt ccggagaaaa gcgtgttttc caaaaagaaa
    17221 caatgagata agcaataaag gtaaattaaa aagcagtgaa gtgacagaag gagcgaatcc
    17281 aaaaagatta tgcaaaagca aagcaatacc agtaacccca ccatctgcca gcttagatgg
    17341 aatattgatt cctgtcacag ctaatccgta gattcctgcg cctaaaatga ttccgcacaa
    17401 ttctgtaaat aaatttaatt ttttcatttc tagcctcttt tcttttgaaa attttcagca
    17461 acttctttat tatactgact tatactctta cttcaagagg aaaatgaaaa aaaattattt
    17521 ttggctgttt ctttttattt atcaaataag gagtggaaaa atgcgagcag cagacttatt
    17581 gacaattctt acaaaatcac ccaaaaaaac agagtatcaa ggagtttttt tggctcaaga
    17641 acaaaaactg gtgcctgtga caatggtcca gataaataaa gcaaatcaat ttatcttttt
    17701 atttgaacac ggcaaagcac cacttgctat gaaagacatc tttctttttt tgatgaagaa
    17761 ccgtgagaaa gctgtttatt atcagtcaaa agaagaactc attcctcttt atggagtgaa
    17821 agagatagaa aataaagtgg tgatataagt aaaaataaga aaacaagacg tttatgatgt
    17881 caaaacaacc attttttaca tttttggcaa aaaagtgtca tgatacagta taatattcgt
    17941 tgaacaggcc aataaaggtg ttctccccca cgagatttct actttattgg ctgtttcttt
    18001 ttattaaaat aaaagttgtg tgtgtaaaaa agatatagct gattccaagt gacaatttcg
    18061 tatagatttt tatggtattc gtagtgaaaa aacgagaacc aaaaagttga tccgactttg
    18121 ttgcttggat tctttttttg tcagcatatt tagaggtatt tttttctttt ttttgttcgt
    18181 gctgtaaggt taaggcaaga caagttagtt gggaaaaagg aaagaaatgt ttatacttaa
    18241 agaataacag aaaggaaggt cgcatgaata attttataca aacattaagt gaaagaaaag
    18301 gcgagttgct ggaagctgca tttcaacatc tgtccatttc tctcatttct ttgctgattg
    18361 cagcactgat tgctattcct ttagcgattt gggcagccaa tcataaaaaa atggcagaag
    18421 tcttattgca gatcacgggt gtgctccaaa cgattccttc acttgcctta ttaggtttac
    18481 ttatcccatt tgtagggatc ggaactgttc cagcattgat tgcacttgtt atttacgctt
    18541 tgcttccgat tttccaaaac acgtatattg gtctagctga aattgacccg tctattgaag
    18601 aagcagcggt agcatttggt atgtccagaa tgagacgctt gctgaaagta gagcttccca
    18661 tcgcattacc tgtcattatc tcaggtatcc gaactgcctt agttttaatc atcggtacgg
    18721 ctactttggc agcattgatc ggagcaggtg gattagggac atttattttg ttaggtattg
    18781 accgaaatac acctgttttg acattgattg gtgcgatcag ttctgccttg cttgcaatta
    18841 tattcagcgg actgattcgc tggttgcagc ataagaaacc tcgatattcc atcattactt
    18901 tagcagcagt ggtgtgttta tttggcggcg tttctttata tcagtctgcc ttgtttaaaa
    18961 atgaaaccat cacgattgct ggaaaattag gagcggaacc tgaaatcctg atccaaatgt
    19021 ataaagaatt gattgaagac aacacaaaaa cagaagttga attaaaaccg aattttggca
    19081 agacgagttt tttgttcaat gcactggatc aaggtcaaat cgatatctat cctgagttca
    19141 caggtactgt cctagaaagc ttggtgaagg tacctgaagc aatgaaaagt gctgatttga
    19201 caaaagaaaa aacatatgac gaagcagaag aattattgaa taagcaattc gatatgacat
    19261 tattaaaacc aatggcttac caaaatacgt atgccttggc agtcaagaga tcttttgcga
    19321 acgaacatca acttaaaaag atttccgatt tggcagctat ctctgatcag atcaaagcgg
    19381 gattcacact ggaatttatt gatcgttcag atggatataa aggaatccaa gaagcatatg
    19441 gcttgaattt ttcaagtgta caaagcatgg agccaagttt gcgttaccaa gcaatcaata
    19501 atggagatgt caatattgtg gatgcctatt ccacagatag ccagctcaag gagtacgatc
    19561 tagtgactct agaagatgat cgagggttat tcccagctta tcaaggcgca ccgctgatga
    19621 aaaaagattt tgctaaagaa catcctgaaa tcgttaaagc actgaataaa ttaagcggaa
    19681 aaataacaga ggatcaaatg attgatatga attaccaagt caatgtcgaa aagaaaaagc
    19741 cgacagaagt agcacgaatc ttcctgaaaa atgaaggatt agtaaaggag gaagatcagt
    19801 gactaaatta atcgagttca aacatgtgca aaaaaagtat gatggaaagt atgtcatcga
    19861 tgacctaaat ctggcaatca aaaaaggaga aatctttgtt ttggttggtc cttccggtag
    19921 tggaaaaaca actactttga aaatgatcaa tggattatct aaaccatcag caggagacat
    19981 ctacttcaaa ggaaaatcgt taaatgaata taatctgcag aaaatgcggt ggaatatggg
    20041 atatgtgctg cagcaaatcg ctttgttccc gaccatgaca gtcaagcaaa atattgaagt
    20101 catccctgaa atgttaggtt gggaaaagca gaaaagagca gaccgtgtag atgaacttct
    20161 tcaaaaagtt ggcttatctc ctgatattta tcgagatcgt atgcctagag agttgtctgg
    20221 aggagaacag caacggatcg ggatcatccg agctattgct gcaagcccag atgtgatttt
    20281 gatggacgag ccatttagcg cattagatcc gatttcaaga aactcattac aagaattggt
    20341 tttgtcctta cacgaagaat tgggcacgac catcgttttc gttacgcaca atatggaaga
    20401 agcaatcaag ctaggtgatc gtattgcatt tatgaaggat ggagaaatta tccaatgtga
    20461 cacaccagag cagttattga tgaatcctaa aaacgactac gttcggcatt tctttgatga
    20521 accgaaacag acgaaagagt ggcgagtaga agatttagtc gtcaatggat atttcttaaa
    20581 tgaaatacca gaaaatgctc gtcaacaagt ttgctttgat acgcctatga aagaagtata
    20641 ttcgcttctt tcggtgtatc caagcattgt gatagtagaa aagcaaagaa gtattgggtc
    20701 gctgacaagt aaagaaatct ttgctttttt aagtcgagag gaggaaggaa atgaaaacat
    20761 atgatgcaat catcatcggt tcaggtgtga gcggcttaag tgctgcttat ggattgaaag
    20821 aagcaggtaa aacagtacta gtggtcgaag aagatctatg gggcgggact tgtcctaacc
    20881 gtggatgtga tcctaaaaaa gtcttgttaa gtgcagtaga ggcacgtaat cgggtaaaac
    20941 aattgagtgg aaaaggtttt aacgagatcc caactgccaa ctgggaagaa cttcaaaaat
    21001 tcaaacgaac atttacggat ccagtcccag aaagccgaaa aaaacaatta gcagaagctg
    21061 aaatcgatca tctttcagga accgctcgtt ttttggatga ttcatctatt gaagtcaacg
    21121 aagaagtctt ccatgcggat tacttagttt tggcaaccgg gcaaagacct acgatcttac
    21181 cagtggaggg aaaggaatac ttgaaaacta gtgcagactt tttatcattg cctgtactgc
    21241 ctaaagaaat catttttatc ggtggtggtt atattgcttt tgagctagct acgattgcca
    21301 atgctgcagg gagcaaagta accattgtcc atcataatca acggccatta aaagaatttg
    21361 aggcgtcttt ggtagaggaa gccgtccatc aaatggaagc atctggcatt cagtttgctt
    21421 ttggtgttga aacccaaaag atcatttcag aaggtactcg ctatcgttta gtcggaaaag
    21481 agacggaatt agtagcagat atgatttttt gtgcgactgg gagacagccg aatacagaat
    21541 ctttagcact tgagcaagcg aatatcgtct ttgataaaca cggaattgca gtcaatgatt
    21601 atctgcaaac gagcaatcca aaaatttttg cgtgtggaga tattgtttca aggaaaaccc
    21661 caaaattgac accagtcgcc acttttgaag gaaattatgt agctaagcgg ataacggatg
    21721 caacaagcga acctatcaaa tatccgatta tacctacgat cgtctacgcc agtcctaaac
    21781 ttgctgaagt aggagttaca aaaagtcacg cctcttcgtc agatcaagtg gtagagatgg
    21841 atcttaccag ttggttcacc tatcatcgtg tcaatgaacc agttgctaag gctgaattga
    21901 cctttgacca gcaaaattat ttgattggtg ctgcagtgat tagcgagcaa gcagacgaat
    21961 tgatcgatga tttgacactc gtcatcaatc aaaaattgac taaaaaagag ttggatagct
    22021 atatcatggg gtatccgaca ttggcaagtg atctctccta tttattgaaa taatcagcat
    22081 gataactaaa gcgcttgttg ctttttcctt cttgtgctac actttaaaaa atgaatacct
    22141 gtttctgggg atgtcgtaga cgacatgaga gtaagttgtg aacttagacc cattgaacct
    22201 gtcagttaat actggtgaag ggagaaacat agcagacgct tgaagcgggt tactatgtcg
    22261 tgcccatttc aagcgttttt tgttattcat attagaagaa aggaggtaac aaaatgaaga
    22321 aaaatcttta tccagcagtc agtatggcat tcattttaat tatttggcag attgttgtca
    22381 tagtttggaa aatacctgcc tttattttac ccggacctgc tgctgtattt tctgcattag
    22441 cggcagatgc acaagtatta ctttcccatt ctgtcacgac attaaatgaa gcagtgcttg
    22501 gtttggtaat agctagcgtt ctttctttta ttactgcctt ggcaatggat tattggaagt
    22561 ttttagaaat gtctttttat ccgttactag tgatttcaca aatgttgcca atcatggtgt
    22621 tagggccatt acttacccta tggtttggtt tcggtatgct tccaaaagtg atccttgttg
    22681 tcttgataag ctattttccg atcgtagttt ctttttcgga tacattgagg aaagtatcaa
    22741 aagagcaaat catctttttg aaaacgatgg gggcagatac agggaagatt tatcgaatat
    22801 ataaaatacc agcgggttta tccggcttct tttccggttt aaaagtggct gctacttatt
    22861 gtgtcagcgg agcagtcgtt ggagaatggc taagcgctca agcaggctta gggtattaca
    22921 tgatacgcgt aaaaaacagc taccagatcg ataaagtttt tgctgcgatc atttgtgtca
    22981 ttctattgag tttattgctg aatggcgctt gttcattatt gaaaaaaggg tattatcgta
    23041 tgctttatat tttttaagag aaggggatca aatgaaaaaa ttatggcttt tattaccgct
    23101 actgttgctt ttatccgctt gtggcactgc aaaagaaaca agtagcaaac aagaaataaa
    23161 ggatttgaaa aaagtgacac ttgttttgga ttatgtaccg aatactaatc atactggcat
    23221 ctacctagca aaagaaaaag gctattataa agaggctggt ttaaatgtcc aaatcatcga
    23281 accaggagat aattcgacaa gtattggtct agtaggtgcg gacaaagcac aatttggtgt
    23341 aagttatcaa gaagatgtca cttatgctca cgcagatgga cagaatatac cagtcaaagc
    23401 aattgctaca gtgatcaaac ataatacttc tggattcgcc accctatcag acagtaacat
    23461 ccattcacca aaagattttg aaggaaaaac atatgcaggt tggcaaagtc caagtgaaga
    23521 agctgtctta aaagctgtga tggaaaaaga cggcggggac ttttcaaaac tgacaatggt
    23581 aggaagcaat ggagaagggc cagaaagctt aggaaaatcc tcagatatcc aatggtactt
    23641 tgaaggttgg gatatgatca aagcaaaaga agcgggtatt gaactaaact atatcccatt
    23701 gaaagaatta gatgaacggt tagattacta tactccggta attattacga atgatcaact
    23761 gatcaaaagt gatccagaat tggtacagtc ttttatggat gccacgaaaa aaggctatca
    23821 ggaagctatt aaggatccaa atgacagtgc taaactgttg caaaaatatg caaaagaaaa
    23881 tgatcggacg tttttagaag aatcacaagc attcttgtca aaaaattata cggatgatcc
    23941 tgagaattgg ggattgatgg aagaaaaagt ttggcgcaat tatacagctt ttatgcagga
    24001 aaacggattg atcaagcaag atgtaccttc gcaagaacta ttcactaatc agtttataaa
    24061 ataggagtga tagatatgtc aatccaaatc agccacttga atgtagtcat tgaaaacctg
    24121 aaaatattag aagacatcca tttcactatc cctaaagata cctttacatc gattgtcgcg
    24181 ccaagcggag ccggtaagtc aacattgctg aaaactttaa caggagtcca gcctatgact
    24241 tctggaacga tcaaagtaga cgatcaaaaa gtaactggtc tccatacagc atttagttat
    24301 atgccgcaag aagatatgtt acttccttgg ctgagcgtct atcaaaacgt tacgttatat
    24361 caaaaaatca atcatctaac aatcaatgaa gaacaagtaa gggattatct ggatatcttt
    24421 gggttaaacg gctatgaaca ttttttgccg gaacaattat ctggcgggat gaagcagcga
    24481 acggccttgt tacgaacaat catgaatcct tcttcttact tgcttcttga tgaaccattt
    24541 ggagcgttag atgctatgac cagagggcag atgcaagact ggatgttgaa gctgcctaaa
    24601 aaagcaaagc ggactacttt acttgtgacg catgatatcg aagaagcaat ttatttatca
    24661 gacaggattc ttgtgctttc cgcccgtccg gcacatgtga ttgctgagat tcaagtgcct
    24721 gaaaaacgac ggtcacgtga atggctactg cagcaatcag agttgaagca aacgatttat
    24781 cagttattgg caggtgaatt agatgttaag tgatgctcat tgtcatttag atgggagtca
    24841 gagtttagca ctccttcagc aggaacacac gattttgacg atcatcaatt gtgattcgcc
    24901 agaagaatgg aaggaaaaca gacagcttgc agcaagtaag actcaagcct taagttacgg
    24961 tatccatcct tggaaagcag atagctatac gtttgaacaa gttgagcctt ttttgaaaaa
    25021 agcaaggatc atcggtgaaa tagggttaga taatatttgg acgaatgtac cgatgactac
    25081 acaaaaaaaa gtatttgagc gacagcttgc ttttgcagcc ataaatgaga aacctgttgt
    25141 actgcacaca aaaggatgcg aaaaagagat cttaaattat atccaagctt accctaatca
    25201 ctatttgatc cattggtatt cttctttgga ctatcaacaa gactatattg atttaggctg
    25261 ttatttcagc attggtcttg atttgaaaaa gaatccagca gtctggcaac tagctaaagc
    25321 agtcccaatc gaccacttac ttattgaaac ggatggacta catgcagcag agtgggcttt
    25381 aggggggatt ttttcagaaa aagattatgt ctcactgctt gaagaacagt taaagacaat
    25441 cgctgagatc aaagagctat cagttgaaga agttaaaaaa aatacttatc aaaacttgga
    25501 acgtttcatt agattaggta aataaaaaag agatgtgaca caactagtgt cgcacctctt
    25561 tttggctttc tttgtataaa agtaaactgt ttgattaata aatgaatctt agtaccaacc
    25621 gtttgcttcc cagaatgctt tcgccgcttc ccaagaacca taacgtgaag taacatattg
    25681 ttctgctact ctttcttggt ttgcagcaga gtagtcacca tttaagtaag aagaatctaa
    25741 ttggtaacgt ccgatgtaac gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg
    25801 tgcgatccat tcttttgcag agcttgtgct tgctggagta gcagcagttt ctgttacagc
    25861 aggagcaggt tgtgtttcag caacaggcgc tgcttgtttt tccgtttgaa ccgtttcttg
    25921 tacaacaggt tgttcagctt ggactggtgc ttcttgaacg gctgcttgag gttcagcagc
    25981 tgcttgtgca gagccttctg ttgggattgt taattgttgt cctgagtaaa tcaggttaat
    26041 atcagaaatt gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt
    26101 ttgagaaatc gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc
    26161 agtcgttccc atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt
    26221 aagtgatgtc atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg
    26281 aggaatactt taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca
    26341 aatccgcgtt ttttgtaata aatacagtaa tctatgaaat gaaaagggtt acgtttaata
    26401 aaacttgctt ttttgttttt gttcaccata aatatttatt taagaaagta ttaacctgca
    26461 tttttctcta taaaaaagat tttttaaata gataaaaaag gaggattaaa tgagtatttg
    26521 atagtattta tattaaaatt acatatgtaa tttaaaaacg cttgacattg tgtttgagat
    26581 cacttacttt tagcatgtaa aagtattgga ttaaggagct atgcaaatga aaaagaaatt
    26641 tattactggt gggattgtcg ttgcatttct atgtctaatt ggctacacag gcacgcggta
    26701 cgcaaatgaa attattttgt ggggtggaga gacagatatt gatacaatca atgagaatct
    26761 gacacagctt gatcatacat tgacagataa agagcaagcg attacagatc ttaccgctcg
    26821 actagcacaa aaagaacaga cattgcaaga ttcaaaggca gatgtccaag aataccaaac
    26881 aaaagtaaat gaattagaaa accaaaaaaa tcaatcggca gcagaaaaac aaaacttaga
    26941 aagtcaatta gtcagcaagg atgcacaact acaaagcaaa caaaatgaaa tcaatgtcaa
    27001 actagatgag atcaaccaaa aaaatgatga aatcaatcat ctgaatgcag attggacagc
    27061 aagactacaa gaagcacaag caaaactttc agaattacaa aatactgtaa atggtttgaa
    27121 tcaacaaatc gcaacactga cacaagaaaa aacaaatgta gaaatcagtt aacagataca
    27181 caaaagaaat tagacgaagc aactgctgaa aactcaagct tgaaacaata tattcaaaag
    27241 ttagaaaaag caaaagatga agtggaagat acagctgata aatctcagca aattgttgaa
    27301 gaacatttgc gtaaataatc tttcttaaca agtaaaccta aattagtaaa gaagcaacag
    27361 taatctatac tgctgcctct tttttttagt acatgtcctt catcttcgca ggaagtgcca
    27421 atatgatttt aagaaaggta atagacaaaa agtcaaaaag ataaaacaga gtttcttctt
    27481 tacaaaggga atgtatgttc gtataatggt attgaggtga aggttatgga gaaaaaatat
    27541 ggaacagtag ataagatccg tactttgcaa gttagtgcca gaccgttgat ccgtttcagt
    27601 ttaaatgggg tcaattgttt gattgcttcc catagtttga acttcctagc tgaagtagac
    27661 gaagggatga agttagtcgt tacaggttat tataataata gaaagcaatt tgttgtgaga
    27721 tcctatcatg tgttagggaa acccaaaatt gtggtagaat atgagaaaag tctataccca
    27781 agaaaaaagg tccgacaaga tgaaagaata aactagaaaa caagcggctg agacaaaaat
    27841 gtcctagccg cttgttttgg aaagatggat gcagacgatg ggatttgaac ccacacgagc
    27901 atacgctcac aagaacctca atctatatat aactacatgt atttaagtat ttgtgatgaa
    27961 tcactaaact ttccaaactc atttgaggga tattgcttaa agattgaaca gatcaattcg
    28021 aagccctatt agtattcgct caatgggggg atcagaggcc ataaaaagag actagtcatt
    28081 actagtctca ggtagtggaa ttgtaggatt ttaaacgttc ctggagagta ccggtatgta
    28141 actcgaagag gtgattatca tagtcgtaaa agtaaattga agaagcctcg cctttcacac
    28201 gagaacgtcc tggttcgaca gttaaaccta acatttggat ttttgagaca aacgaatcta
    28261 tatcttgttc gtcaatttta aaagcaatat gattgtatgt ctttggcagt ttattcgacg
    28321 aattctgcat tactgcaatc cataggtcct taactaagaa aaatttttct ggatataatg
    28381 aaaatttttt tgttgactat cgtagatttc ttttgcatca aataaggtat ttaacaatta
    28441 agtatttaaa agataacttt taagttatct ttaagtaatg cttaaagcta tgttatactc
    28501 tattaggaaa tataagaagg agtataaaaa tgaacaaaca taatagaaaa ataacgaata
    28561 acaaagaact gatcttgtta ctaataggga tttggggtat ctttttactc tttaatatgt
    28621 atatgccgac tatgagagcg gatgacgtag tttatgcaag tagattagat gaacttggct
    28681 atttgggtgc ttcgatagaa cattataaga catggagttc aagaattatt atagaactat
    28741 tcttaatgtt cttttctaaa cactttatgc tatggaaatt attaaattct acgattatgt
    28801 taggaattgt agtattactt tgcaagtat
//
LOCUS       DASHWW010000027        28684 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.027, whole genome shotgun sequence.
ACCESSION   DASHWW010000027 DASHWW010000000
VERSION     DASHWW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.027"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(23..1189)
                     /locus_tag="U2R64_001423"
     CDS             complement(23..1189)
                     /locus_tag="U2R64_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8918248.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1201..1554)
                     /locus_tag="U2R64_001424"
     CDS             complement(1201..1554)
                     /locus_tag="U2R64_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEM8918249.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1682..2704
                     /locus_tag="U2R64_001425"
     CDS             1682..2704
                     /locus_tag="U2R64_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEM8918250.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            2723..2884
                     /locus_tag="U2R64_001426"
     CDS             2723..2884
                     /locus_tag="U2R64_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918251.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(3143..3577)
                     /locus_tag="U2R64_001427"
     CDS             complement(3143..3577)
                     /locus_tag="U2R64_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918252.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(3687..5546)
                     /locus_tag="U2R64_001428"
     CDS             complement(3687..5546)
                     /locus_tag="U2R64_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEM8918253.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(5664..6823)
                     /locus_tag="U2R64_001429"
                     /pseudo
     CDS             complement(5664..6823)
                     /locus_tag="U2R64_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(7130..8554)
                     /gene="araA"
                     /locus_tag="U2R64_001430"
     CDS             complement(7130..8554)
                     /gene="araA"
                     /locus_tag="U2R64_001430"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HEM8918254.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8570..9268)
                     /locus_tag="U2R64_001431"
     CDS             complement(8570..9268)
                     /locus_tag="U2R64_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEM8918255.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9225..10886)
                     /locus_tag="U2R64_001432"
     CDS             complement(9225..10886)
                     /locus_tag="U2R64_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HEM8918256.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11104..12504
                     /locus_tag="U2R64_001433"
     CDS             11104..12504
                     /locus_tag="U2R64_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HEM8918257.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12756..13835)
                     /locus_tag="U2R64_001434"
     CDS             complement(12756..13835)
                     /locus_tag="U2R64_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8918258.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13921..14880)
                     /locus_tag="U2R64_001435"
     CDS             complement(13921..14880)
                     /locus_tag="U2R64_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEM8918259.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14892..16403)
                     /locus_tag="U2R64_001436"
     CDS             complement(14892..16403)
                     /locus_tag="U2R64_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEM8918260.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16425..16988)
                     /locus_tag="U2R64_001437"
     CDS             complement(16425..16988)
                     /locus_tag="U2R64_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEM8918261.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16994..17857)
                     /locus_tag="U2R64_001438"
     CDS             complement(16994..17857)
                     /locus_tag="U2R64_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8918262.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17871..18767)
                     /locus_tag="U2R64_001439"
     CDS             complement(17871..18767)
                     /locus_tag="U2R64_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918263.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18942..20231)
                     /locus_tag="U2R64_001440"
     CDS             complement(18942..20231)
                     /locus_tag="U2R64_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8918264.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20203..21720)
                     /locus_tag="U2R64_001441"
     CDS             complement(20203..21720)
                     /locus_tag="U2R64_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEM8918265.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21918..22808
                     /locus_tag="U2R64_001442"
     CDS             21918..22808
                     /locus_tag="U2R64_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEM8918266.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22881..23705)
                     /gene="nadE"
                     /locus_tag="U2R64_001443"
     CDS             complement(22881..23705)
                     /gene="nadE"
                     /locus_tag="U2R64_001443"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEM8918267.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23717..25189)
                     /locus_tag="U2R64_001444"
     CDS             complement(23717..25189)
                     /locus_tag="U2R64_001444"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEM8918268.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(25826..26188)
                     /locus_tag="U2R64_001445"
     CDS             complement(25826..26188)
                     /locus_tag="U2R64_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEM8918269.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            26411..27163
                     /locus_tag="U2R64_001446"
     CDS             26411..27163
                     /locus_tag="U2R64_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8918270.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(27303..28226)
                     /locus_tag="U2R64_001447"
     CDS             complement(27303..28226)
                     /locus_tag="U2R64_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8918271.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(28241..28513)
                     /locus_tag="U2R64_001448"
     CDS             complement(28241..28513)
                     /locus_tag="U2R64_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918272.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8478 a         5987 c         4883 g         9336 t
ORIGIN      
        1 ttttcccatc tgtctctttt tgttattctt tctgcttttt caacggattt tcttcataaa
       61 gagaagagat tgttgtgtac cattcaaaaa catgagtaat cactacttta gctgctgcat
      121 aaacaggaat ccccaagatc acaccgatga ttccgaacaa tttcccagaa gtcagcagaa
      181 ctaataaaat cgttactgga tggattgcta actgattccc tagtactaat ggagagatca
      241 agcgtccttc tattgtctgc tctactgcaa aaacgatcag tactttgatg atcatgaatg
      301 gacctgctac aatggctaaa aagatagccg gaatcatcgc taaaaatgat cctaagtaag
      361 ggatcaggtt taaaaaaccc gcaataatcc ccaacgtgac agcatactct aaaccaatga
      421 ccgcaaaacc aatcataaac atgattgcca cagcaaaagc cacagttagt tgtcctctta
      481 tataagaaga aacttgacta ttcatttcac tcagcacatt caacgtcggt ttttgcatgc
      541 gtgtcggtaa aaatttgaca aaataaggtg ctaattgttt accgtctttc aatagataaa
      601 ataagataaa cggcatcgtc agcagagcca ctaaaatagt cgctaccgcg ccgacaaaac
      661 ttccaagact ctgaactgta ctcttagata tatcttggat catatcgcct gccgaattca
      721 tgaacttatc acctgctgtt tccaactgtt cgcgaaattg gttgaacagc gggtcccgca
      781 aaatctcggt taatttatta tcaatcgtat ctacatattg agggaagtta ctgatgaagc
      841 tcactgtttg ttcctgaatc ttagggatga tcactacgct cccccatgcg attagtgcaa
      901 caaccaaaac aaacagccca atgatactgt aaagccttgg tacttttcgc ttttcaaagt
      961 aatcaactac cggattcatc aagtaataca agattcctgc taaaatgata ggcagaccta
     1021 cgattgctaa aaattgccag attggtgcaa acaaatatga aacttttgta aataaaaaga
     1081 cgatcagcaa tattaacaat acaacaagta aggctgtgac tacttgatta tttaaaaacc
     1141 agcgccaaaa ccacgatacc ggtctgttct tcttattttt tccttccata attcctcctg
     1201 ttagttataa aaaatttggc ttcccaaacc aatagcaggc agtctatgcg gatgaagata
     1261 gattccattt gcaatttgtc cttcttctgg acaagcatca aaaatcaatg atacgtgagc
     1321 tactgtcttt aaattcccat tggccatcgg accgacataa tcgatcgtat atacctgatc
     1381 atcaaaagca attgttccgc ctgctttcaa agaaaaaggt tcgtcttttg atacttcttg
     1441 aatcaccgaa tattttcgta aggcagctgt tgctgtttta tcgaacaaaa tcagcatggg
     1501 ttcttccttg tttattgctt ctgtcccaat ttctgtaatc tttgcctgaa tcattgcact
     1561 ctctccttta attgctttca aaaacagtat aacacattct cattctttag ccgtgtggaa
     1621 taattatgtg atagaataaa aacgaaaact atttcattac aattaggagg aatcagctca
     1681 tatgatcgaa aagataattt taggaaccta tacgcgtcgc gaaagtaaag gaatctatac
     1741 gatcgacctt gatacagaaa aagaagaatt agccaacctt tcattagctg ttgaagaaaa
     1801 tagccctacc tatgtagcaa aaagtaaagc tggcaatctt tacacagtta ctagtgtgga
     1861 tggattaggt ggtgccggtg cgtacgataa ggattttcat tttttgaatg cggtaacaga
     1921 gtctggcgct cctttgtgtt atgtagcggt tgatgaagca cgtcaattac tatacggggc
     1981 gaactatcat aaaggtgaag taaatgtcta ccatatatta ggagatggcg aactgaaagc
     2041 agcagattca atattccatc aagaagcgac aggtcctcat aaaaaccaag atcatgcgca
     2101 tgtccactat acggatctga ctcctgacca acgattagtc gtatgtgatc ttggtacaga
     2161 tcgtgtgtat acttatgatg tgtccgaaaa cggcaaattg aatcttgtaa ctaccttcac
     2221 tgcagagcca ggaacaggcc ctcgccatct tgtctttcat ccaaatggac aattcgctta
     2281 tttatttggt gaattagaca gcacagtccg cgtgctttct tataataaag aaacaggtgc
     2341 ttttgaagaa ttacagaaaa tatcgacctt gccagaagaa ttcgacggtg aaaatggagg
     2401 ggcagctatc cgcatttcaa atgatggcaa gttcctttat gcttctaacc gaggacataa
     2461 ctcgattgct gtattcgcag tttttgaaga tggttcccac attcaaaaca agcaaatcat
     2521 ctcaacagaa ggggattttc cccgcgattt cgcactagat ccaagcaata attttgtcgt
     2581 gtgtgccaat cagaacaccg ataatctgac attatatcgc cgtcatcctg aaacaggatt
     2641 actggaatta ctgaaaaaag atgtctatgt accagaatgt gtctgtgttt attttgatcg
     2701 ttagtaagaa aaggagaatg aaatgaatca gcaagacgta ttagacagac tacgggaaga
     2761 actaaatatt cctttctttg atgggaaaat cgaagataaa gagtatagcg aagaggaata
     2821 tcagaaactc aaagccgatt tacagaacta ctttgaacaa tatgtacaga atgtagaaaa
     2881 ctaatcagct ttccatacta tctgaaaaga acatcaggac aagacttttc cgtctatcct
     2941 gatgttcttt tctacaaata aaaaaccgcc gagatggtta gactcgacgg aaaaggagta
     3001 tttactcgat tttgagtaag tacaaggttg ttgttggtta taggtatgtc attatcataa
     3061 aggattttga tcactctatc ataaaggtaa tattacattt atattagata actctagttt
     3121 ttattgttat caaagatttc ttttattttt tcaacaacaa attagtcatt ttttggatgg
     3181 cagctgtcaa ttggtctgtc gcttggtctt gttttgcttc agatgtattg aatagatctt
     3241 catctacccc tgattcaaga tcgatacttt ggatcatttc ttcacagcct gctacatatg
     3301 aaagataagc tttttcaaaa tttttatgaa tgcccattgc ttttgctggt ggacgcaaag
     3361 tactgacttt cataagcatt gcccgatatt tttttgttcc ttcttcaaat aacaggatga
     3421 tctcttcaag agtcgatttg tccagttcac ttgtttttcc ttcatcaatt gcgtttctga
     3481 tcacttcata tttcggatgc attccttctc cgattgcttc tgtttccttg acgatttgat
     3541 cgatggactg cacataatag ccaatattcg gtaacatgtt cgttttccta ctttctccat
     3601 tgttgttatt atttattcta cttgttttta tcctcaaatg acaagtactt gaaaaaattt
     3661 aatggtttct atacagctcg ccattcttat tcgtgctcaa agaaaccatc tgctaaacta
     3721 tattgtttcc ctgcgacaat gtcatattgg atcaattgat attcgtcgta aatctcttgt
     3781 tgcgagcgat tgaattgcgc ttctttatac cactgtccgt tttgatagta cagttctcgt
     3841 tcaaacgccg gaagttcctg ttctaatgat aaaagcagct gataaaagcc atttgttgtc
     3901 tgattcgtct gttccattag attcgctgca aaataaaacg gactggtgat tgcatcgtga
     3961 gtcgtttgct tttctaattc tcctttactg tcgaacataa gaaattgtgt ttcatgcaat
     4021 gtttgtttgt cattttttgc ttggatcgta tctgaataga tccctggaag atgatccccc
     4081 caaaaaacaa ctaaagtcct tctagaaaga ttcttcaatt cttccgtgaa ctgcttcagt
     4141 gccgtgctgc tataggaaat atcttgcaga taattctcta agtcaagtgt cccacttcca
     4201 tctgaagttt ttgcaggata gtctagatta tcatactttc catcgtaggg catatgtgtc
     4261 tgcatcgtga ctaaatgaat gaactgaggt gttttttctt ccttgagaag tgtcattact
     4321 tctttgtaag ctgactcatc agaaatatat ggattattct ctatcgtatc cgtataggtc
     4381 atcgtacgct cgctgatgaa ctggtcaaat cctaatgtct gataaacatc ctctctttta
     4441 tacatcgaag tattgtatgg atggatcgct gtcgtctggt atgattgtgc gtttaacgct
     4501 gaaacgatag aaggaagctg atccattttt ggtacaagca tcgtgtaagg ggtggtgagt
     4561 tgcgcattaa ataacgccat agaaaaacca gtcaatgctt caaattcgat atttgctgtt
     4621 ccaccgccat agttttgaga aagcatattg ccactatatg tttgatcagc tacttcataa
     4681 taatctgcca atggctcacc agatacttct acgccgttta atcgactagg atctgagaaa
     4741 ctttcactca tcacgaacac gatgttcggc gactcttcct ctacagtttt atttttttca
     4801 tcggctagct tctggtattt ttcagtgatt tctttgatct tttctttcga atatccttca
     4861 ggttcatcca ttggttctac cttcagattg tacaaaaacc caccgataaa accagtgtta
     4921 tagtagttca ttttctggct gtaaggtatc catagtgccg ttttattata tgcttttcgc
     4981 aacaaattat cgggattgtt gaaattactg atatacccta gcagtccaat tgccacaagc
     5041 agtgtcgtta atcggatcaa ttggaatcgc cttccttttt tcaggcttcg aaacatgtac
     5101 cagcaaaaca atcctatcac ggttcctgcg gcagctaaga tcactgtaaa cagcatagtg
     5161 ccggtcatat ctttcagcaa tccgatttca gtgatcatct tcaaatcgtc tggataaatc
     5221 ggttcttgcc gataactcat tttcatataa tttgcaaaac ctaatacacc gatggctacg
     5281 acatacgtaa gggaacctaa agggacagat cctgctagtg caatcagaaa aataagaata
     5341 atcagcaaga cgagacaggc taagaagaat ttttccgtat gccaagaaaa agcaaatttc
     5401 aacgcaaggt ctacggatag atcattttga caccactgca aaaataaatt actaaaaaca
     5461 acaagaaaaa agatactgat gattgctgct gttcctttta aaatcttttt ctgtttggtc
     5521 gaaagtctgc ttatatatct tttcaaatgc ttgctccttc atttctatca ataaaagaat
     5581 gttgcttctc ttattttagt tgtacgaaat tcgaaagtaa agaacggaaa gaagaattaa
     5641 tgaaatccaa atattctctt tctttatggc ctttctggtt tctttaataa gcggaccttt
     5701 cgtactccag aaattttttc tagctgttgt ttcacttgat tgagctgttc aaaatcagta
     5761 ctgtctatgt caatcaatat gtagacatgc tcattcttat ggttacgcga tatatctgcg
     5821 atcgctagct cgttctcatt cagcagagaa aatatctctg ctaatatatt ggttttcttt
     5881 tgataaaata tagtgaatcg aaacggcgct tggaaaaaca ttcgtgcgga tggataattg
     5941 accgcttctc taaccgtacc gaacaaaaga taatctttta aggcttcaac tgccaaacgt
     6001 ccgctgtctg ccaaagcttc ctgagtcgat cccctagatg aggcaacata agtatacggt
     6061 cattttctaa gaactcttct tctggaaaat cagtcaagta tttagccaga tgttgttttt
     6121 ccaatgcttg cataacagca tatttatcaa caatttcact tcttcctaca ttgataagta
     6181 cagcatcttt tttcattttt tctatattcg cctgatcgat caatcctttt gtatcttctg
     6241 tcaacggcag catgactacg atgtaatccg aggtagaaag aactgtttct aaatctgctt
     6301 gccgaacata atccaactgg gcatcgcgga tagaataacc caagacatcc atccctaagc
     6361 tatagcaact tagcgctact tttgtgccta tcgctccaag accaagaaga ccgatggttt
     6421 tgccttgcaa ttctcgtccc acataagcac ttcttttgtt ttctgcctgt tctaaaatat
     6481 taggacctgt tagtgtttgt accatacgac ttgcttcgat tatcggacgg gaagataaga
     6541 gcaaacagca caaaacaagc tcttttactg cattagcatt tacacctggt gtattcatga
     6601 cgatcgtccc gttttcagaa gctttttcaa cgttgatcgt gttcacccca acaccagctc
     6661 ttgaaattgc tagcaaatct ggtgtaagcc attcatcttt cactttcgta ctacgaataa
     6721 ctattccttc ggctggcaaa tcatctatta ttttgaaata ttccccttgt aacttttcta
     6781 tctcttgttc tggaatagca tcaatcaaat gaacgtgata cataaaaccc cctccttact
     6841 aacaagtatc tcgaaatttc tgcaattaga caactgttta ccatttgact tcctagaagc
     6901 aaaaagagca gttagagcag agtaggctga gtgataaaaa taaggctatg acaagttact
     6961 gccataagcc ttattttcga gagcaaaata ttgagggtga gatatcttga taaatggtgt
     7021 tccgttagct gacattgata ataagactaa atttcaaaaa agttgaaaag caaatttcgt
     7081 caatctcttc ttatttctta aaactaagtg gctttttcac aacctctttt tatctaataa
     7141 ccactgtttc caactcaact aattttgccc acgtttcaat ttgatctgtt gttagattta
     7201 gcgagacaac ggtatgatga ccgccacctg cctgaatcca tgaatggaca ccttcatgga
     7261 aattcggttt agttttccat aacacacgtg caacaggtaa attaggtgct tcagtcgttg
     7321 gttcaaaggc ttctacttca ttgatcagca gtttataatg cgtaccgaaa tctgccatcg
     7381 atacgactac cccttctcct gctttcccat caaatacaag acgcgccgga tcttctctat
     7441 ctcccattga taaaggagaa acaacgattc ttggtttcgt cgcagcaagc gtcggatcta
     7501 cttccatcat atgggattcc aagattgctt cttggccact agctagctcg taagtataat
     7561 cttccatgaa tcctgtatct ttccctcgag ccatgatttt cagcaaccga tcaatcgctg
     7621 cagttttcca gtcgccttcc ccagcaaaac cgtatccttc tgccatcaaa cgttgtacag
     7681 ctagtccagg tagttgtttc attccataca ggtcttcaaa attagtcgta aaagcgttat
     7741 agcctccttc ttctaagaaa cggcgaatac cgatttcctg ctgagcttgt acttttacat
     7801 gttcctccca tgtcttttct tcataatcac catagtcgaa ggtatacaat tccttgtact
     7861 cttcaaataa ttgatcgact tcttcgtctg atacgcgatc gattacttgt acaagatctc
     7921 cgataccaaa ataatcaaca gtccaaccaa attgaatctg tgcttccact ttgtctcctt
     7981 ctgtgacacc cacgtttctc atgttgtcac caaaacgagc cacttttatt ccaaaacttt
     8041 cattataggc tactgcaaca tccatccaat cagcaatctc tttttggatc tcaggtcgtt
     8101 tccagtagcc aacgacgatt ttattttgtt tatttaatcg agcattgatg aacccatatt
     8161 cgcggtcacc atgagcggat tgatttaaat tcatgaaatc catatcgatc gttttccaag
     8221 gaatgctttc gttatattgc gtagctaaat gaagcaatgg tttttgtaga agctttgtcc
     8281 cgcggatcca catttttgct ggtgagaaag tatgcatcca agtgatcaca cctgctactt
     8341 cttctcgata attgacctct ttcatgattt ttgtgatcgt atcagcagta actgctaatt
     8401 cttgaaggcg gattggataa ggcaattggc cattttcatt cagttcatcg accatttctt
     8461 gtgcatgttt ctttacttct cgcagtgctt cttccccata taaatgctgt gatcctacaa
     8521 caaaccaaaa ttctttttct ccaatattca acataattag ccactccttt tatttgtttt
     8581 gtccgtaata cgcatttttt ccgtgttttc gtaaataatg tttatctaaa atccgttgag
     8641 gcagctcttc tgaaaatgaa ttgagctgtc tggtaaataa attcatcttg catacttcat
     8701 ctagtacgac tgcgttcatt accgcacttt gcgcatcttt cccccaagta aatggaccgt
     8761 gtccgtgtaa aagtacccct ggaattgcta agggatcaat tttgcgttct ttgaatgttt
     8821 ctatgataac ttttcctgtt tcatattcgt acccgctgtc gatttcctgt tgtgtcaaaa
     8881 atcgagcaca aggtaccgat ccataaaaag tatctgcatg cgtcgtcccc atcgcaggaa
     8941 catccaatcc tgcttgtgcc cagatcgtcg cccatgtcga gtgagtatgg acgattcctc
     9001 cgatttgagg aaatgaacga tataaaacag catgagtagg cgtatccgaa gagggattga
     9061 gtttaccttc aatgatatga ttgtccaagt ccacaacgac catgtcgtct gctgtcatct
     9121 cttcataact gactccgcta ggtttgataa cgaaatatcg tgtttcagga tcaaaagcgc
     9181 tcacatttcc ccatgtatat ttgacgagtc cgtgtttagg caagtcaaga tttgcttggt
     9241 atacttcttc tttcagttgt tccagcattt tctatcactc ctttttcttg caattgatga
     9301 atcgctgttt tttcaatgtc gatcccctca cggtaacgtc tcataaatat ctgatagcct
     9361 gctatttctt ctgctgaagg tgtgatggtg attccttggt cttgtccaaa cacgtcttct
     9421 gccaagaagt tttctaaaga cttcccatgt cgatccatca tataggctgc taataacgcg
     9481 attccccacg ctccaccttc tccggctgtg tccatcactg taactggtgc ctccatagca
     9541 gatgctagaa tccgctgtcc aacttctggt gttttaaaaa tccccccatg ccccactaaa
     9601 cgatcaattt ggacattctc agatttcaat atatccattc cgattctcat tgcaccaaaa
     9661 gcactggcta aatggatccg catgaaattc gctaaatcaa aacggctacc tggtgtacgt
     9721 acaaataatg gccttccttc atttactcct gtaatgtttt caccggaaaa ataaccataa
     9781 gaaagtaatc ccccgcaatc cgtatcgcct tctagcgctt tgttgaataa taccgtgaat
     9841 aatttatctc tgcttatctc catacccaaa gaattggtaa attcttcaaa aatactgacc
     9901 caagcattga tatccgaaga gcagttattc gtatgaacca tgcctactag ttctcctgaa
     9961 ggtgtagtga ccatgtcgat ttccggatgg acattttcta gttctttttc taatacgatc
    10021 atagcgaagg cggaagtacc agccgaaatg ttccctgtcc ctttggctac actgttcgta
    10081 gcgaccatac cggttcctgc atccccttct ggcggacaaa ccgggattcc tggtctcaaa
    10141 tttcccgtag ggtcgatcag ataagcccct gattcgctta acttgccagc ttcttctcct
    10201 gctactagaa ctttaggcaa aatgtgatcc aagtcaatcg ctacgtgcgc tttttcgatt
    10261 aactgaccaa aaatattttt catttcttga tggtaggttt tcgttgaagg atcgatagga
    10321 aacatgcctg atgcatctcc tacgcctagt actttctcac cagtaagctg ccaatggaca
    10381 taacctgcaa gcgttgtcaa aaaattaatt tctttcacat gttcttcttt attcaaaata
    10441 gattgataca aatgagcgat actccatctc tgcggaatat tgtattgaaa tttttccgtt
    10501 aatattcgtt ctgcttcttc agtgattgta tttcgccaag tacgaaatgg tactagtaac
    10561 tgttccttgc tatcaaatgc tagataaccg tgcatcattg cactgaaccc aatcgacccg
    10621 attgtcgtaa gattctcgcc atagatttcg aatacttctg ctgccatttt tcggtaactg
    10681 acgcgcagtc ctttccaaat atcttctaat gaataggtcc agataccatt ttctagtttg
    10741 ttttcccact cataactacc agcggcaata ggagtaaaag atgaatcaat caatacagct
    10801 ttgatcctag ttgatccaaa ctcaatccct aaagatgtac gaccatctat gacatctaac
    10861 atactttgcg catttacttc cttcataatg atttaactcc ctccttctcg tcaaacctga
    10921 tcaaaccgtc tttttagtag cgcttacaat gattattgta tacttttgta cgtacatgtc
    10981 aagcagttat ttacaagaat acaataaaaa acacttgttt tgtacgtaca taagttataa
    11041 aatgaaattg cttacaaaat ctgatcaacc gccttctcga aattctagaa ggagagaata
    11101 cttatgaaaa aagaaaaaaa agtttcctca tcgtttattt atttttttgg cgcatttggc
    11161 ggcattctat ttggatatga tattggtgtt atgaccggcg ccttaccttt tttacagcat
    11221 gattggggtt tggcaggtaa agcttctttg ataggatgga tcacgtcttc ggtcatgtta
    11281 ggtgcgatcc ttggcggctc tttatctggt cttctttctg ataagcttgg acgacgaaaa
    11341 atgattcttc tttctgcact tatttttatg gctggttctg tcctttctgc atctgcccct
    11401 cacaatggtt cttattttct gattgcagca aggattcttc taggtttagc tgttggcgct
    11461 gcatctgccc tagttcctgc ttatatgtct gaaatggctc ctgctagact aaggggaaga
    11521 ttgtcaggga tcaatcaagt gatgattgct tctggcatgc tcctttccta tgttgcagat
    11581 tatttgctaa aagggttgcc tgaaacgatg gcttggcgcg tgatgttagg gctcgctgct
    11641 gtccccgcgc tgattttatt tttcggtgtt ttagctctac cagagtcacc gcgttttctt
    11701 atgcaatctg gccgcttgga agaggcaaaa agagtattga actatattcg gacaccaaaa
    11761 gaagctgaac aggaattcga acaaatccag ctgaatgtca aacaagaaaa gacaaccgga
    11821 acttcttggc atactttgtt tttagaaaaa tatcgttcct tagtcattgc cggtattggt
    11881 gtagcagtat tccagcaatt tcaaggagct aatgctattt tttactatat tccgctgatc
    11941 gtagaaaaag cgactgggca tgcagcgagc gatgcattga tgtggccgat catccaagga
    12001 atcattttag ttgctggttc tttgctcttt ttggttattg cagacaagtt caatcggcga
    12061 actttattga aaataggcgg tagcgtgatg ggactttctt tcatcctacc agctgtttta
    12121 ggaactgtac tggatgctca tacaaattcg ttgttgattc tcttgttttt atgtatttat
    12181 gtcgcatttt attcttgcac atgggctcca ctgacatggg taatcgtagg cgaaatattc
    12241 ccactagctg tccgcgggcg agcatctggc ctagcctctt cttttaattg gattggttct
    12301 ttcctagttg gcttgctttt tcctgtgatg actgcttcta tgtctcaaga aatcgttttc
    12361 ggcatttttg ggatcatctg ctttttaggg gttttattta ttcaagagat cgtaccagaa
    12421 actcgtggga aatctttaga ggaaatcgaa caaagtgcat ctaaaaaaac ttatcctaaa
    12481 cgtatttcta tccatcattc ttaaagaggt tgtgacagaa gtggtcagct tcaagaaata
    12541 agaaggaacc gcttagtttc cagtcacaag gaacaatttc aaaaaacagc ttctcatgtt
    12601 tgatgaatat tgtgacttgt gaccagttgg taggagaaca ccgtttagtg gagaggtggt
    12661 gaaagaaacg ttcagccttg agcgatgaca aaagctctca caaacattgc gacgagtaac
    12721 cgtaggagca ataagaggcg gtaaaaaccc gtctcttatt tttcgttttc tttcactgtt
    12781 tcccgttcaa ctagtacagg ttcatagaga atatttggct gtgcctgtcc tttttcaatc
    12841 gttgtgacga tccaccgtgc ggcatcttgt cccaactttt cttttggatg cgtcaatgtt
    12901 gtcaattttt tattccctaa atggcttaaa gaagaatcgt ctgttcctac gatcgatagg
    12961 tcatctggaa tatgatagcc attttctgtc aacttatcta gcattaaact agctatttga
    13021 tcgttatagc aaatgatgcc atctaaagct tgttcttctt tcaaccgttg tactgttttt
    13081 tcagcgattg tttctcgtgt ttccgtggtg aaagtaatga tatcttccgt caaaaaacgc
    13141 acattatact gttcacacgc gctgataaaa cctttcatcc tgtattttcc ttgaagatcg
    13201 tcgatttttg tgatgaacaa cagacgctga tgtccttttt ttatcaaata ttctgctgcc
    13261 ataaaaccga ctttcacatc atctaaacaa atataagagg catttaactc ttcataagca
    13321 gcattgatca tcaccatcgg aatgccttgt tctctcaaag caacataaag tgctaagttt
    13381 gggttatact gattactttt cgtaggctca acgatcaaac catctacccc ataagcaatc
    13441 attttcttca aacactcttt ctccaattcg tgatcgttat tcgtactggc taaaagcaat
    13501 gaatacccag attctcgtaa ttcattttcg attcctcgga taatcgacgg aaaaatataa
    13561 tcagagagat atgtggtgat gacaccgatc gtttttgttc tgttcaatgg tgttttttct
    13621 ttcttatagc tgtcatctac atatgtgccc gacccttttt ctttacgcag atagccctca
    13681 tttaccaaca cagcgattgc ttgccgaatc gtatgtctgc tgacgtcata tatttcttgc
    13741 agcttgaatt ctgagggaat ggttgtattt acttcgtatt cctcacgaag gatcttttgt
    13801 tttatctctt ctgcaatatc ttgatatttt gccatttgcc ttgccccttt ttatttgtac
    13861 gtacatatat cataacgagt ctgcaaggtt tattcaagca aaaatcaagg tttcttgtgc
    13921 tcataaggca tacggaacag gttcaccaaa ttctggaaat ccttgctcat tccacgtaaa
    13981 gcattgcgcg ttcgcgtgcc gattaggatt gtctaacgga tccccttttt ggttcttctc
    14041 tggtcgagca tgatagatca aaatatcaaa gcacccgtct tctgaaaccg taaacgagtt
    14101 gtgaccagga ccaaattgct tatttttttc agaagaaacg aatactggct ccgataattt
    14161 atgccatgat tcttttaata aaagattctt gtgctcatca gcccacagca ggcccatggc
    14221 atagttttca tctgttgcac taccagaata cgtaatgaat attttcccat tgcgagtaag
    14281 gactgctgga ccttcattta ctgaaaaacc ccgtttttcc cattcatact caggtataga
    14341 aaggaggatc tgcttcccct ttaacgtcca aggattatcc atttcggata gataaagatt
    14401 agaattccca gtaatttcag gatcttgttg ggcccacaca taatatagct ttccttgaga
    14461 agagaaagtt gttccgtcta aactgaaagt ttcccttttc gtttttattt gtcccttttc
    14521 tatccaatct gtattcattg gatctatatg ctgattttca agtacgaaca tgcggtgatg
    14581 atgagattca tcacgtatag ttttatgatt gcttgcagca aagtaaatat accattttcc
    14641 attgatataa tggacttcag gtgcccagat caattcactc atcggtcctt cttcatgagc
    14701 ctgccataca atcaggcttg cagcatgttc taattcattc agtgactttg cccttcttaa
    14761 ttcaatcact tggtagcctg gaaccgatcc tgtaaaataa taataaccat ctgtatgttt
    14821 atatacccaa ggatctgccc gttgccgaac gataggatta ttataaagtg tcttcatcat
    14881 aacaaatttc ctcacatttt ctttattcta attacattcc aagagtattt ttctatccct
    14941 acatttaatt cgtcatgttt ttctattgaa aaatagttta tttcaggttt tattttttct
    15001 ggttcttcac gtgtattttt gtccaacaga tcgctactgg ttaatgtgta gtgctctcct
    15061 tgatctagca aattgaaatc atgttcaatc gttatctttt gttgttcatt tgtgcgattg
    15121 atcaagaaaa tagtcagctg attgccgtta tctacgatca cactgtccac ataaggaaca
    15181 ttttttatct tttcacaatc ataaacaggg caaatgattt gttgtttcaa tacttgacct
    15241 ttagcatatt tcgataagtg ttgcatcaca taataagttg gattcctcca tgcttgtcct
    15301 ttagcatctg tcagtattaa aggtattgtg tttactaaca atgattgaca actaatcttt
    15361 acgcgatctg cgtgtcgtaa aatagccagc cctaatgaac caaataataa tgtatcttcc
    15421 atagtaaagt aacaccaatc gatgggacta ccgacttcaa aatccctatg tcttttttcc
    15481 ggttgggcat gtacattcca ttcatcaaac gctagataca ttgttttctc acttctcaaa
    15541 tatcctttta cataatcaca agtagcaacg atttcttcaa tttgacgatc gaatcgataa
    15601 gcttttgcaa ggtatgtcgc tgtatcatca cgctcatttt taggaggttt agtcaagtct
    15661 tcttcatcat acttatcaat atagttatgc aaagctaaat aatctacatt ctcataagct
    15721 tcttctaatg cgatacgatc ccattcaggg tacgatggta aacgtggcgt agagcttcca
    15781 actaagattg tttcaattga atcatccact aacttcatga cttttgaggc ttcatttgct
    15841 aacctaccat attcataagc actcttagcc cccacttgcc atggaccgtc tagctcattc
    15901 cctaaacacc ataatttaac gccaaaaggc tttttttgcc cattttttat tcttaaatca
    15961 ctccagaagg ttccttttgg aaaattacaa tattctacta aattttttgc ttcatcaatt
    16021 ccttttgttc ctaaattcac cgtgaatatc ggtttcgctt gtacatgact gatccattta
    16081 aaaaattcgt ggagtccaaa agaatttggt tctatacctc gccatgctaa atcaattttt
    16141 tttggtcgtt gttctttcct acctacagta tccacccaat cataaccaga tgtaaagttt
    16201 cctccaggat agcgaatgac acctaattct aattccttta cataagagag gacatcttgt
    16261 ctaaacccgt caccatcagc tgtttcatgg cccggttcat aaatccctgt atagacgaca
    16321 cttcccatat gctcaacaaa tgagccaaac agccgagaac tgatctctcc taccgtaaaa
    16381 tcctctctga tttttacttt cacttcttcg tccaacagct ttccctacct ttcatttcct
    16441 atagtcaaga taatagatac aagtttccat acgccaccag caaagataaa aataaaagga
    16501 gggaaaagaa atatgagcag tacaaatcct aataacaata cgcaacaaag aatatttctc
    16561 aaaaaatcaa aaaatacttt ccatgcactt tgttcaaaaa tttgtaaaaa tgtgatatct
    16621 ttgttttcag aaatcacata tatccaggat aaaagaaaca tggaataaat aagtaaaact
    16681 acatatccac taattgaaag tacgattgtc tgttcttcta ataattgatt aacaagaaaa
    16741 taaataatga tcgttaacag actaaggaac aagttcttac caaaatgttg ctttattcct
    16801 tgaaagaaaa aataaatgat atttcctgat ccctcacctt tccattgcgc cattacataa
    16861 aaaacagcac atgtagcagg cacgatagta ataacaggca aacacacgat tacccagaga
    16921 atacctaata agatgtaatc agaaaccaca atcaactgtc cataaagttt agtctcaact
    16981 attttcatct tcctcactct ttcattccag acatagctgt tccttgaaca aaatatttct
    17041 gtgcaaaaat ataaaccact agtaatggca gcattgaaat aaccgttcca gccattacag
    17101 gtccataaaa agaaatgttc tgccctgtaa ataaagctaa ccctgctggt aaagttctca
    17161 tttttgaact acttgtcaat atcaatggat aaagcaagtc attccaacta ttcatcagcg
    17221 tgaaaatccc taatgataaa agagtaggtt tgctcaatgg caacatgatt ttcaaaaaaa
    17281 tattaaactc acttaatcca tcaatgcgtg ctgcctcttc caaagaatct ggtaaagtaa
    17341 taaaaaagga acgcatcatg aagataccaa atgcagttgt catacgagga atgatcaaac
    17401 ctgcataagt atcaagcatg ccaagcaaat tgacttcaat aaatagagga atcatgaaga
    17461 cttggaatgg gatcatcatt gtcagcaaaa cgaaatagaa caaaactgat tttcctttga
    17521 aacgcatacg agcaaatgca taccccgcaa gagaatcaaa gaatacagaa gtgatcactg
    17581 tccctccagc aaaaatcact gtatttttga tgtaatctaa taaagggatc gttgtccaaa
    17641 ccttaatata gttatctagg gtatagctat ctgcaaatat tctaggcgga aatgagataa
    17701 tgtctttttc gtgtttaaaa gaagaaataa tcagccacaa aaaaggaaac gcaataacca
    17761 acaatataac tagcatacta atcgttcgaa tgattttttt accactaact gcttttcgac
    17821 tattcacagt aactgtaatc gagctttctg gtgccataca ggtttccctc ctatttcatt
    17881 tgtttttctt tccgtgacat gtacacatta gtggagatag ctatagttgc aacaatgata
    17941 aacaaaaccg aagacagtgc tgatgcatag cccaattcat aaggtgctgt aaatcctcga
    18001 ctgtaaatat attgaacagc tgtttctgtc ttaaattgtg ggccaccagc ggttgcaaca
    18061 tatacttggt caaacacttg catcgaacca atcagattcg ttaaaataca aaaacctaag
    18121 gagggaacga tctgaggtag cgtaatgtta aaaaactgct gtcgatttgt tgcaccatcc
    18181 atttgagcag attcatacaa agagggagag attccctgaa tagcagtcaa gagaatcgtc
    18241 atagtaacac caaaattctt ccaaacagtc atgatggcta ccgtcggcat agcaagggtt
    18301 ggatcgcgaa aaaattgagg gatcggcaag ccgacttgtg aaaacaagta aggaatcgcc
    18361 cctacattcg gatcaagcaa catagaaaaa ataatcgcaa ttgacgtcaa tgaacaaata
    18421 actggaatgt aaaatgtcga acgacaaaaa cgattgaatc tggtattttt agataatgct
    18481 actgctgcta ataaaccaac gataatttgt gttggcgttt cgagtacggt gaaatataaa
    18541 gaatgaatca acgaattaac tgctcgttca tcactaaata tacgtgtgaa attttcaaaa
    18601 cttacaaaat ttcttgatgt aaagaaaata ttcaaatctg taaaactaat agcaaatgtt
    18661 cctaaaagcg gtatgacagt aaataataat aaaactaaaa aagatggagt taaaaacaaa
    18721 tacgcagcac gatcaggacg attccaatat ttggtgaatc cgttcatata gtccacctca
    18781 tctttcattt tgataaaata tacaatcttg gtttaaacga atctgaataa gatatccgaa
    18841 caatcgctgt gatttttgca ataacaccta tctgcaaata ctaggtcgat cattcagata
    18901 tctgtatctt gccaacagtc tatcctgtat aaagttctgt actatttttg cagtaattga
    18961 ttgatggcat catctgcatc gttcatgagt gtctcaggat cttctcctgc taataatttt
    19021 tcaatcagtg gattgatgat atcgttattg atcgcagaga tttgggtaaa acctggtaaa
    19081 tatggctctg catagtccat ttgtttcgat aattcagata caataggatc attttttact
    19141 tcttcatctt ttgctactga atccaagtag gcaggaaaac cattttcgat actccatttt
    19201 ttaccaattt cagttgtatt ccaatatttc aaaaactcat agacagcttc ttttttatta
    19261 ttatctgtac ttgccggaat ggcatatcct acgccatcta aaatagctgt ttttttgtct
    19321 gaatcactcc cttgtggtaa ggtagtcaca ttataatcaa tctcgtttgc tttcaatccg
    19381 ttatttaacc atggcccatt gatttcaatg gctagttgac cagcattcat taaattgtcc
    19441 atttcggcgc cagaaatcga ttctggacca gtcttgtcta catggatcat tttttggatc
    19501 gcttttaacg ttttaaggtt ctcaggagac gcaaattcag acttagtata atcatcgttc
    19561 actaatttac cgccatttgc taacatccag ttatataacg gtgcagttcc atccttattg
    19621 aagacaaaac ctgatacatt tttactacta tcagttaatt ttggtgccat ttctgtcaat
    19681 tcttcccaag tagtaggtgg ttgttcagta tctaatccag cttgtttaaa caaatcatta
    19741 ttccaataca tatacatgcc ttgtacctgc atggggacaa aatactgttt accttctact
    19801 tcacctaatt caatagccgt ttctttaaaa tcagatttat ctactccatc atattcccag
    19861 aaatcgtcta atggttgtac cgctccgttt tctacatact gtgcaaaatc tggataattt
    19921 aatgcaataa agtcaggtgc ttttttagaa gaaatcgctg taggaagttt ttcattcaaa
    19981 ttggcccaag tcatgatatc catttcaatt ttgatgtttt tatcatttgt tttattaaat
    20041 tcattaacga tttcttgcaa tatttcacca tcagatgcag taaacccatt ccaaaaagtc
    20101 aaagtcactt ctttatcaga atcagattct gctgaacttc cgccaccgca agctcctaaa
    20161 atacctgttg cagctaccaa caaagagcca attaaccatt ttttaccttt cattttttgt
    20221 tcctccttca tctgataaac gacatctgac cacattccaa gatagcggtt tcaataaaca
    20281 attgattttc ccatcttcag cttttacatt tgttgaatga cttggtttta cttgttcact
    20341 tttaggaaga ttagttgctt ttgtatcaaa tccactcatt tcagaaaaat caatcactcc
    20401 ctctaatgat aattcagaca agtgaacagt tagattcatt tcttcttctc cacggttaac
    20461 tgcaaatatg acaagttctt tgtcatttat tacggctata ctttctaaat acggcacttc
    20521 ttcaaaatct tccgtcgcat agtttgctga acgaatttgt gggcttaaca cctctccttg
    20581 tccatacaca gcagcttgca taaatggata atagatcgtc tgtctccaag cttctccgtt
    20641 tgtttctgtc ctgattggtg caataacatt taccaattga gcaagacaag caatctttac
    20701 tctatctgca tgtttcaata aagtgattaa tagacagcct aatagtaatg catcttcaaa
    20761 attatagtta tcttctagta aaggaggagc aatctgccaa ggcgctgctt gctcatcttg
    20821 ttccgctgaa tgataccaaa tattccattc atcaaaggac aggttgatct gcttcttact
    20881 atgtttcttc gccttgactg tatcgcacat cgctgtcact tcagaaatga accgatccat
    20941 gtctaaggaa cgtgcaagat aatgagaaag atcatttttt tggttgccat aatattgatg
    21001 cagagacaaa taatctattt gatcgtacgc ttgatcaaga actgttaact cccaatcacc
    21061 aaatgtaggc atttgccgat tcgaacttcc gcataaaacc acctcaattg aatcatctac
    21121 gagtttcatc gccttagccg tttcctctgc taaccgtcca tattcttccg ctgttttatg
    21181 tccaatctgc caaggaccgt ccatttcatt ccctaaacac catgtcttaa ttccaaaagg
    21241 gctctcttga ccattcgaac gccttaaatc actccaataa gttcctttag gaaaattaca
    21301 atattcgact aaattacgag ctgcatctac tccacgagta cccagattga cagccatatt
    21361 gatttcggcc cccacatgct gacaccagtt ataaaattca tgaatcccaa cttcattcgt
    21421 ttcaattgtc cgccaagcta aatccaacct tctaggtcta tttgctatgg gcccaatact
    21481 gtcttcccaa cgaaatcctg acacaaaatt tccaccagga tatctaatca tgggaatgtt
    21541 caattctttt accaagtgaa tgacgtcttg gcgaaatcca cttttattag ctgatggatg
    21601 atctggctga taaatccctt catatactgc tcgtcccata tgttcaataa atgaactgta
    21661 caaccgcgga tcaactttgc ctacacgctt gacactacta atcaacattg tggcttccat
    21721 aactgacctc ctttaattta tacatgaata atacacctcg ttgaaagcgt tgtcaataat
    21781 ataaatgtta aacttactta ttttttatcg attttaatta accaaaatat taataatgat
    21841 taaaacaaat aatttaatat aacttttatt aacaaatatg ttaatatata agaaaaacct
    21901 tttaagaggt gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag
    21961 cattagctag taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg
    22021 tcaaagattt ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa
    22081 agctagagga agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc
    22141 ttcgtgtcga taaaatcgat atcagttttc cagaaaaaat attcaatgct tttgatacga
    22201 aagaaacatc gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt
    22261 tagctacgat ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc
    22321 gaaggatgga tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta
    22381 attttttaaa tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg
    22441 aatttccttt ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg
    22501 agctaggaac atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg
    22561 attggtatcc agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac
    22621 acttgacgaa tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag
    22681 agcaagacac ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct
    22741 gtactttatt tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact
    22801 acagctgata tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga
    22861 cggctgtttt tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt
    22921 cgtttatgtt gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact
    22981 tcttttcctt ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct
    23041 gcaatcattg gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc
    23101 ggtgcattca atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc
    23161 aaaatgtcgg ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca
    23221 tgatctgtcc ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata
    23281 cgttgacgtg ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt
    23341 aatacttgta cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc
    23401 tggataaagt caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga
    23461 cgaacagcga taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt
    23521 agttgcgcca aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa
    23581 gttttaagaa acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt
    23641 tcttcttttg gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg
    23701 ctcatttatt ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt
    23761 ccatgatagc cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg
    23821 gattcaagtc tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt
    23881 tgatttcgtt tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta
    23941 aaactgggcg agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga
    24001 acatgaagat agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt
    24061 cagatttccc atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta
    24121 ctttttctgc attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga
    24181 tcgatactag cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg
    24241 tcccaacacc ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt
    24301 catccaagtc attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt
    24361 cccgaacacg cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt
    24421 tgattttgtc acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg
    24481 tatcataagt gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg
    24541 cttcataatc atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta
    24601 tcccaaatat cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg
    24661 ctctagttcc ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata
    24721 gtggatcttc tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga
    24781 aattgaccat attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca
    24841 cttggattaa tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg
    24901 ctttaaattc aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac
    24961 gcaagtaagc aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt
    25021 ccaatcctgc aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa
    25081 aaacagcatg taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat
    25141 atagatccgt atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact
    25201 cctcttggca agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa
    25261 tcttccattt tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc
    25321 catctgctaa aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt
    25381 ttattcaatg tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa
    25441 ataagtagat tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata
    25501 accaaatgtc tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc
    25561 cttttttgct tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg
    25621 gaaaggcgaa ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac
    25681 acgtttttaa aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg
    25741 cgagacatca atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta
    25801 ccataaagat gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca
    25861 ctacaatatc tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca
    25921 ctcctacatg gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt
    25981 cgatttcttg ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat
    26041 atgtgtctac caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag
    26101 ccgtattccc aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac
    26161 tattcacagg tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga
    26221 tccaatctta agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc
    26281 tttaaagaca aaaggattta ccttttatca cttaatagta taacataatt tcgtgagaaa
    26341 aaaatacaat tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg
    26401 aggaaaaata atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag
    26461 aaccttgcgc ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg
    26521 ttatcggatt tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac
    26581 aatggcattc aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca
    26641 gaaagcttta atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct
    26701 cttgacaact gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa
    26761 agaaaaattt gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca
    26821 agagattcga caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa
    26881 tatggataaa gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct
    26941 cactctttac ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca
    27001 taagaagtgg ttctcttaca gctggcctga atatcagcca aaagcgcata aaggactagg
    27061 aatgatgtac gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg
    27121 tgcagcaaaa gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa
    27181 caaaaaagta cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt
    27241 atgctaactt ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat
    27301 attcatcgtt gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac
    27361 aattgaaatg ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga
    27421 agctcgctga tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag
    27481 ctttgcaaga tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc
    27541 tctttaaaaa agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca
    27601 agtgattcat caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta
    27661 taacttagcc tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc
    27721 aaataagtaa gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt
    27781 tttcccttga tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca
    27841 tctagtgtat tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct
    27901 tcaagatacc ttcgctcttt ttctttatga tagcccgtcg gtaaaagtgt cactttgtaa
    27961 tcataatcaa acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg
    28021 gtataaggca gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt
    28081 gcattaggga tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca
    28141 tctacatatg gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc
    28201 tttgcgatat ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt
    28261 gtaaatagtc taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg
    28321 aaaaactgat ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca
    28381 ttggtatttc ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg
    28441 atcccttgaa ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta
    28501 cataagtatt cattgcaagc cctccttttg atactttgag tatagtgtat gaaacgcgtc
    28561 tcatagcaag gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa
    28621 gtctcttatt ttaaattgaa tacattataa tgatactgta aatatatctt tattattagt
    28681 gaat
//
LOCUS       DASHWW010000028        28599 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.028, whole genome shotgun sequence.
ACCESSION   DASHWW010000028 DASHWW010000000
VERSION     DASHWW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.028"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            234..1874
                     /locus_tag="U2R64_001449"
     CDS             234..1874
                     /locus_tag="U2R64_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HEM8918273.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2028..3350
                     /locus_tag="U2R64_001450"
     CDS             2028..3350
                     /locus_tag="U2R64_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEM8918274.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3412..3843)
                     /locus_tag="U2R64_001451"
     CDS             complement(3412..3843)
                     /locus_tag="U2R64_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918275.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3907..4743)
                     /locus_tag="U2R64_001452"
     CDS             complement(3907..4743)
                     /locus_tag="U2R64_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEM8918276.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4933..5235)
                     /locus_tag="U2R64_001453"
     CDS             complement(4933..5235)
                     /locus_tag="U2R64_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEM8918277.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5261..5692)
                     /gene="ruvX"
                     /locus_tag="U2R64_001454"
     CDS             complement(5261..5692)
                     /gene="ruvX"
                     /locus_tag="U2R64_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEM8918278.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5689..5955)
                     /locus_tag="U2R64_001455"
     CDS             complement(5689..5955)
                     /locus_tag="U2R64_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEM8918279.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6209..6934)
                     /locus_tag="U2R64_001456"
     CDS             complement(6209..6934)
                     /locus_tag="U2R64_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEM8918280.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7300..7370)
                     /locus_tag="U2R64_001457"
     tRNA            complement(7300..7370)
                     /locus_tag="U2R64_001457"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7336..7338),aa:Gly,seq:ccc)
     gene            7487..8239
                     /locus_tag="U2R64_001458"
     CDS             7487..8239
                     /locus_tag="U2R64_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEM8918281.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8255..8734
                     /locus_tag="U2R64_001459"
     CDS             8255..8734
                     /locus_tag="U2R64_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEM8918282.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8985..10565)
                     /locus_tag="U2R64_001460"
     CDS             complement(8985..10565)
                     /locus_tag="U2R64_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEM8918283.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10558..11301)
                     /locus_tag="U2R64_001461"
     CDS             complement(10558..11301)
                     /locus_tag="U2R64_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918284.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11477..12253)
                     /locus_tag="U2R64_001462"
     CDS             complement(11477..12253)
                     /locus_tag="U2R64_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8918285.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12501..13337)
                     /locus_tag="U2R64_001463"
     CDS             complement(12501..13337)
                     /locus_tag="U2R64_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEM8918286.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13348..14277)
                     /locus_tag="U2R64_001464"
     CDS             complement(13348..14277)
                     /locus_tag="U2R64_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEM8918287.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14470..14823
                     /locus_tag="U2R64_001465"
     CDS             14470..14823
                     /locus_tag="U2R64_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEM8918288.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14897..15553)
                     /locus_tag="U2R64_001466"
     CDS             complement(14897..15553)
                     /locus_tag="U2R64_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEM8918289.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15779..17713
                     /locus_tag="U2R64_001467"
     CDS             15779..17713
                     /locus_tag="U2R64_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8918290.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17799..19022)
                     /locus_tag="U2R64_001468"
     CDS             complement(17799..19022)
                     /locus_tag="U2R64_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEM8918291.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19016..20914)
                     /locus_tag="U2R64_001469"
     CDS             complement(19016..20914)
                     /locus_tag="U2R64_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HEM8918292.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(20908..22026)
                     /locus_tag="U2R64_001470"
     CDS             complement(20908..22026)
                     /locus_tag="U2R64_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEM8918293.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22109..22942)
                     /locus_tag="U2R64_001471"
     CDS             complement(22109..22942)
                     /locus_tag="U2R64_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8918294.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22935..23852)
                     /locus_tag="U2R64_001472"
     CDS             complement(22935..23852)
                     /locus_tag="U2R64_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918295.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24079..25203)
                     /locus_tag="U2R64_001473"
     CDS             complement(24079..25203)
                     /locus_tag="U2R64_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8918296.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25386..26294
                     /locus_tag="U2R64_001474"
     CDS             25386..26294
                     /locus_tag="U2R64_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918297.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26435..28048
                     /locus_tag="U2R64_001475"
     CDS             26435..28048
                     /locus_tag="U2R64_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8918298.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         8892 a         5620 c         4868 g         9219 t
ORIGIN      
        1 tatttatcta tctaacatat cctttattct tctacttttc tttctttagc atataagaga
       61 tacgcatagt aatcaagcaa ggattgttga tataaaaaga acaaataccg ctattttgat
      121 ttcttttgac tctattactc atataaataa aatttattat acctgctctt tttgactata
      181 tcctcatctg actcctatac ttcgtttgta ttaaaactta ggaggaatca ttcatgctta
      241 cagggctaaa cttattaaat aatccttttc taaataaagg aacagctttt acaaaagaag
      301 aacgggcaaa atacggaatc actggtatgc ttccaagtac tgtccaaaca ttggaacaac
      361 aatctgtcca agcttacggt caatacttaa gcaaacagac cgatttggaa aaacgtatct
      421 tcttaatgaa tctattcaat acgaaccgga cattgtttta taaattgatg ggcgaacatt
      481 tagttgaatt catgcctgtc gtttatgatc ctgtcgttgc ggattcaatc gaacaataca
      541 acgaaatttt cttgaaacca caagatgctg tatttctttc aatcgacgaa ccagaaaata
      601 tcaaagcaag tttgaaaaac gcagcagatg gacgcgacat tcgtttgatc gttgtgacag
      661 atgcagaagg aatcttaggt atgggtgact ggggtgtgaa cggtgttgac atcgctatcg
      721 gtaaattgat ggtctacact gccgcggctg gtatcaatcc tgcacaagtc ttgcctgtat
      781 caatcgacgc tggtactaat aacgaagaat tattgaataa tccattatac ttagggaatc
      841 gtcatgctcg tgtagaaggc gaaacttact acgaattcat tgatcaattc gttcaatcag
      901 ctactgaatt attcccagaa ttgttattac attgggaaga ttttggacga ggaaatgctg
      961 caacgatctt agaaaaatac gaagataaaa tcactacttt caatgatgat atccaaggca
     1021 caggaatcgt tgtactagct ggtgtattag gtggattgaa tatatcaggt gagcaattga
     1081 aagatcaaac gatcttgaca tttggtgctg gtactgctgg tgtaggtatc gcaaacatcc
     1141 ttttagatga aatgatccgt caaggtgtac ctgaagaaga agcacgccaa catttctatc
     1201 aagtagataa acagggttta ttgtttgaag atacaaaagg attgactcct ggtcaaatcc
     1261 cattcgctcg taaacgctca gaattcacta atgctgatga attgacaaac ttagaagcag
     1321 ttgtaaaagc aatccatcca acgatcatga tcggtacttc tacccaacct ggagcattca
     1381 ctgaagaaat cgtgaaagaa atggcggctc ataccccacg tccaatcatc atgcctttgt
     1441 ctaatccaac aaaattggca gaagcaaaag caaaagattt gattgaatgg acggacggaa
     1501 aagctttagt tggaacaggt atccctgctg ctgatgtgga atataacggt gtaacttacc
     1561 aaatcggtca agcaaataat gcgttgatgt acccaggttt agggcttggt ttgattgctt
     1621 caacagctac acgagtaaat gctgaaatca tttctcaagc tagtcgagca ttaggcggaa
     1681 tcgttgatgt aacaaaacca ggagcagcta tcttgcctcc agtagcaaaa atcactgaat
     1741 tctctcaaac gattgctgaa actgtcgcaa aatcagttgt tgcacaaaaa ttgaatcgtg
     1801 aagaaatcac ggatatcaaa gaagctgttg aatctgctaa atgggttcct gaatataaat
     1861 ctttagaaga ttaagattgt tatagtaaaa gaacatacag aaactttgta tgacgtctaa
     1921 aaagaaaaaa gcgactgcgg caaaacagca gccagccaac tactgctctt ttgccgcttc
     1981 tctttggctt ttttcatacg atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa
     2041 caacaaccgc aactgcagtt gaggaaaaga aaaaagaagg gttttggtca acaaaaatta
     2101 ccggcgtaag tttgcccctt tatttgatca tggtccttgt cctgatcatt gcaatggctt
     2161 taggaaaatt accgacgaat atgattggcc caatcgctgt tttggtcatt ttcggtaatt
     2221 tatttcattt tatcggaaca aaaatcccta tagtcaaaag ttatttaggt ggtggctccg
     2281 tttttgcgat ctttgcctct gccgcgattg ctacatttgg gatcttacct gagtatgtag
     2341 taaaatccac agaaaacttt gtcagcaata tgggcttttt agacttttat attgctgcct
     2401 tgattactgg tagcatcctt ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt
     2461 ttattcccgt tgcacttatt tcaatggtcg tctccttttt tgccgtagga ctcgtaggta
     2521 tgcttatcgg aaatggtttt gcaaattccg ttttatatat ctcattgccc gcaatggctg
     2581 gtggtgttgg agccggagct gtacctttat caacgattta tgcaaatgtt ttaggtacgg
     2641 acgcttcttc tatcatttcc cgcctgattc ctgcgacagc aatgacaaat gtcctagcta
     2701 tcattggtgc agcgttagtt gctcgtgcgg gacaatcaat gccaaaattc aacggtaatg
     2761 gtaaattaat ggaaaaaggc gaccttggcg atggaaaacc tagaaatgta aaaccttcca
     2821 ttccacaatt aggtgtcggt ttgatggtat cattgacttt cttcatctta ggacaaatct
     2881 gtaactattt tgttcctaaa gtccatgctt acgcattcat gatcattatc gttgttatct
     2941 gtaaaatcgc aaacctatta ccagaatatt acgaagatgc agctatcatg ttcaacaact
     3001 tgattgtcaa aaacttgaca gcagctgttc ttgccggtat cggtattgcg ttattgaatc
     3061 taaatgtatt ggcttctgct ttgacatggc aatttgttgt cttatgtttg acaagtgtta
     3121 tcgcgatttc agtagtttca ggatttgtcg gtcgtttgtt tggtttatat ccaatcgaat
     3181 caactattac tgctggctta tgcaacaact cgatgggtgg tacaggaaat gtagctgtct
     3241 tatctgcagc taatcggatg gaacttattg cttttgctca aatgggcaat cggcttggtg
     3301 gtgccatcgt tttgatcatc tcaggtttct tgatgcaatt actttcttag tcaaaaaaaa
     3361 tacctgatca tcaagtatcg gcttgatgac caggtatttt ttgataaaaa tttacaggat
     3421 tttcaaaaat cttttttgca ttttatcgga atgataaccg atgcgttcat aaaatcggtg
     3481 tgcttctact ctgtattctg cagaattaag tcttattgct gatattcctc gtcttttcgc
     3541 ttcttctacg ccagtcatca aggcctttcc gattcctctt ttttcagcat gtttagacac
     3601 agcaagtgcc ataatattga acatcggatc gctgaaaatc gattcatagg actccgcttg
     3661 tacatagcca gctgcttttt tagaagtagg atcttcatag accaagaaaa aatttttttc
     3721 tggctccttc aacagtttct tcatttgtct caccgtaacg gttaatggta catcatatcc
     3781 taattgttcc gcattgattt ctcgtagtgc ttctgcatct cctaaacgca tttcccgcaa
     3841 catccaaatc accagccaat ttttattttt ttaaatgaat ttttttatca cagtatactc
     3901 cttttttcac ttaaaaaaag acttttcagt gattttgact tgcttgaatc cagatccttc
     3961 taatgtttgc aagatgacga aagcattgta aagattgatc aaaagaacca cgatgacaat
     4021 cgcttgaaaa ataaaggtca ctttttttgg agacaaaacc ctgctaaatc ttgctcccca
     4081 caaacctcca ataacagcag cggggataac ataaaacaac atagataaat caaagcgcat
     4141 aaagctactt gttaaagcaa tcgttaccaa ttttgccagt tgagaaaaga aaatcgtaga
     4201 tagagaatat agtgttgctt cttttattgg caatgcaaac atcagcatca acaaagaaac
     4261 attgactggt ccaccaccaa tacctaaaaa actagctaaa aagcccagaa cccccccaca
     4321 tataaggtac caagtccatg acgtcaaatg aaattttggc tgatgatgct tggtgtagaa
     4381 gaacgcaaaa accaaggtca ataccgtcaa aaaaatttgg atcagctgca catgcttctc
     4441 gttttcaaat aactgtaaaa aaacttcgaa tacaatgttg ccgactactc ctccaacaac
     4501 agctccacta gatacccaac cgacaatctg ccaattcagt gatttcccgc ttgatacttg
     4561 tcgcacagtc gaaacaatgg acatcgtgaa taccgcaact gttgagtaaa aagaaatccc
     4621 tgcaacagaa tgggcgccga taagatcaag aatcggtttg atcaacacgc ctccacccat
     4681 cccggaaata gcgccaactg tgttcgccag aacgatcacc acaaaataaa tcagaccaat
     4741 catcttgtat ttcctttctc ttgtttatat cttttagcga ttgttactct tttcttttat
     4801 tatacagtaa aagaaacaaa cgaggcttcg aaagcttttc tactttttaa ggaaatttag
     4861 tgctaaacga aaaaaccggg ctctactttt cagagagtcc agcttttctt acaccttatc
     4921 gattcttttg ttctattctt cttccgccat gaatgtattg aatacttctt cgatcatatc
     4981 ccattctgcg tctgtttcga tttgttctaa ctcgccttct gttccatctt cgttttcgat
     5041 gtatgcataa gcttgtaatt ctacatcttc atcttctgaa acaccagctg gatataaaag
     5101 aacatagtta cgtccaaatt cttcttgtcc gtcaactgtt agcaagattt cgtataatgt
     5161 ttcatttcct tggtcatcca ccaatgtgat gtgttcgtgt ccttcgtgtt cgtgggaatg
     5221 gttatgttct gtcataagat tacctctttt ctttttatta ttaaaataat tgcttacctg
     5281 agccgtctaa ataattttgt aaaatcatca cagctgctaa tttatcgatg actttttttc
     5341 gtttcgctct tgaagtattt gcctgctcta ctagcatacg ttctgcctga acagtggtta
     5401 gtcgttcatc ttgataatca accggcaagg agaatagttc tttgatcttc tctccatatg
     5461 acatggaagc ttctgccctt ggtccgatgg aattgttcat attcttaggt aatccaacta
     5521 caaaacggtc tacttcgtac tgcgccacta attccttcaa ccgatcaaaa ccaaactctt
     5581 cttctgcctc attgattcga atgatttcta ctccttgagc tgtccagcca aagggatcgc
     5641 tcacagcaac gcctactgtc ttagaaccga catccaagcc cattactctc ataaattcac
     5701 tccatgattt gagaggtagt ctttgacaat tacttccatg atttcatcgc gttcgtgacg
     5761 gcgaatcaaa tttcgtgcat cacgataacg aggaatgtag gccgggtctc cagaaagcaa
     5821 gtagccgaca atctgattga ttggattgta gcctttttct tccaaagccc gataaacaat
     5881 cgctaatgtt tcgctcactt cttttttgcg actatcgtca aaaccaaaac gtacggtttc
     5941 atctgtaaaa cccatgattc tacacctctt tcccgcaagg taattccagc ttaccttcta
     6001 cacccttatt ttactcgaag aaagggaaaa ctacaaacaa atattccaaa cttctgaata
     6061 aattaagaaa cacgatttgt ctgatttttc cttttttctg tggctttttc aaaagccctc
     6121 tttccataaa gtatacgcta tatttctttg aaagtatgtt tttacacaat tttttcataa
     6181 agttcataaa aaattcgaat tgctgctact aatttttcgt tttcgttgct tgccctgtct
     6241 cataattgat ggtgtagcca tcttgaacat tgtagataaa gacattgaat tcaatttttt
     6301 tgtcttcaat gctttctgct tccaactgca cacctcttgc taccagttca tttccctcga
     6361 aatgaggagt gacacgatag cgtacatgat gatttgtttc cttgatatat gccgcaatat
     6421 cattttcgtg ggcaagcatg tacggagcat tcaacgaacg tgtccctgtc attaagtttt
     6481 taatgttatt attttgacca gtcaactgga aaccaatcaa atggctgcgg ttgtataacc
     6541 attgtccgtc acttaatttc ttttgtttcc aacctgtcgg atcaatatac aaaggttctc
     6601 tcttttcagt aggaaacaag tcttttccca acatcgcatt ggcttgtcct actctgttca
     6661 atttgtctat atttgaatag ctttcccatg tccctttgga aagactaaga tcctcttttg
     6721 taaactccgg ctgattccca ttgatttcta tttcttgatg ttttccatca tattctggca
     6781 catccgctac ttgagaagct tgcggtgtgg aatcaaaaat ggttgtaatt tgttggaaga
     6841 tatctgaatc tttttgtgtg gtggaaatac cgagtgcccc tgcaatcaca gcagcgacga
     6901 tccccacgat cgccttggtt gtttttttgc tcatttcttt actcctttac taacagttcc
     6961 ctaaatctta acatatgttc ccctataaat aaatactgga aagaaataga aacagtaaaa
     7021 aaataaaacc agtttttaga cggcttaaga atacaaaaaa agagacggat tcatcgtctc
     7081 tactcaatca caaaacacta tttacaaggt atttattatc attcaaaaaa tttttcttaa
     7141 tactcaaaac taaacggctt ctgtacgacc tcttggtaaa cagtgttcaa aagcttgcat
     7201 ctgcggtaat aagtccaacc aagtcaaaaa cataagaagc ttttttgctt gactattctt
     7261 attacttgat gcagggcagc tttttcacag cctcttttaa gcgggtgacg ggaatcgaac
     7321 ccgcgacatc agcttgggaa gctgggattt taccactaaa ctacacccgc gatacaaaaa
     7381 cagtatacgc ctctttcact ccttcctcaa gtttttttat tctttacgct tccgatatgt
     7441 tttgtagtaa aataaaacta atcaatcaat tattggagaa gatgctatga cgggaaaaga
     7501 attagatctg ttgctggaca cttgtttact cgctgggaaa atcatgatgg aaagcaatgc
     7561 ggagatgtat cgggtagaag atacgatgag tcgaattgct ttagcttctg gaaatttccg
     7621 tttggtcagc tatgtcactc aaaccggtct ctttattggt cttgatcgta cctcgaccat
     7681 ccgaatggaa caaattacca accgttcgat taatttagaa aaagtagtaa aagtaaatga
     7741 tctttcacgt aaatatgttg cttcagagct aacattagaa gaactttact gcgaactgca
     7801 agcaatcgac cgagaccgtt ctttctttcc tgtctggttg caaatcgtta gcgcggcagt
     7861 gatcagtgga acaattatgg tgttatttgg cggaaagatg accgatttac ctgtgacttt
     7921 agtcattgga ggattgggat acgcagctta tctatatagt ttgaaatttt ttagaatcaa
     7981 atttttatcg gaatttttat cttctttatt gattggcata gccgctatct acagcgtacg
     8041 ttttggctta ggaagcaatc aggatctaat cattatcgga tgtgtgatgc ctttagttcc
     8101 tggagttcaa attacgaacg ctatccgtga tttgctagct ggacattatg tctcaggagt
     8161 ttctcgcgga acagaagcga tgatgactgc tacgatgatc ggttttgcga ttgcttttat
     8221 tttccagctt ttttattagg aaaggaacac aagtatgggg acgatattta ttcagttttc
     8281 ttttagtttt ttagcgactg cggcatttgc cgttattaca aatgtaccta ggcgttcatt
     8341 gatttgttgt ggtctttctg gtgcttttgg ctggatgatc tactggatct gtgttcaaat
     8401 aggcggatct gctgcttttg gttcattgct tggttcttta ggagtagcat tcatcagcga
     8461 tcttttctct aaacgtttga aaatgcccgt aacgattttc aatattcccg ggatggttcc
     8521 tctagtccct ggtggtttag cttatcaagc ggttcgaaat ctcgttactg aatcctatcg
     8581 agaagcggct cattatgcgg tccaagcaat tatgattgct ggagcaatcg ctttaggtct
     8641 tgtattatca gaagtcttta accataacat ccgtaatttc aaagtaaagc gtgacgcaat
     8701 catgatgaaa cgaaaaaaac ggctttttaa ataaacgaag tgtaacaaag aaaaggttgt
     8761 gaaagagacg ttcagccttg agcgatgaca aaatatctca caaacattgc gacaagtaac
     8821 cgcaggagca ataagaagta attatgagta ttaaaaaaag ttttgtaaaa atagcttctc
     8881 acatttttac ataaaattga cttaatactg agaaactgac ttttgaacac cctctatctg
     8941 taaaaaaggg gctgcgacat gatttttgtc acggcccctc ttctttattc aaattttttc
     9001 caaaacgttc gttgataata aacgatccat agagcggaaa gtattagaac taaaccgatc
     9061 acaggaatat tcactaacca aaatggataa aacaaagcca acattccgta taagacgata
     9121 agaataatac tgatgatcaa tgaacccatc atagttgcga ctaaacccaa acttcctgaa
     9181 cctctgttaa ataattggtt aatattggtc cagttcagca gcagcaaccg ataatctcta
     9241 gcgaaataac gtagtgacaa taagtagcag ccgaataaag aaccaaatag caagctaggg
     9301 ataaaaaaca aaggcagctg aaaagacagt ccgcttaata atgcgatccc accagttaaa
     9361 aaactctgca atatccatcc gaatctgaac ttttctttta aatattggtt catagagatt
     9421 ggcaaagaac ggataaacag aaaattttct tgatccaaag aaataagatt gctgataaaa
     9481 gaagtctgat taactgttaa gaaagccaat gcgatcccta ccaggaaaac aacaccgatt
     9541 aacttattat ctaaatcagt taattttatt tcgcctccta gggcaaaagc aagaataaaa
     9601 atgattggag ttaacaagga agaagaaaga acttgcataa tcaaattagg ttcttttact
     9661 aattgagcat tgtaactaaa taaaagctga tgcacatttt ggttcttttt atgggttctt
     9721 tttattttga actcactgtt tgaatcagtc agttgctctg taagctttgg tactatcagc
     9781 tgttttacag caaggaaaaa tcccagagcc gtgatagcta gtattcccca acccaataaa
     9841 ccttgttgag aaagtggctg actggcagca tcatagaatg gcaataatat cgaaatcgga
     9901 tgccgatctg ttaactcatt ttcaatagtc cccgtttgat gattcatcca catgattcca
     9961 gcaaatgcga tcagcatcga gctgccaagc aagatactag aaactgtttt tctatgtttt
    10021 ttaaacactg ctgttcgagc caaaccaaaa acaatcaaac tagccagaca aaaaagaata
    10081 atcaaaaata gagaaaacaa aaggattgag ataatgatag taagcaaaat ccctagatca
    10141 gctcgccatc cggttaaaat aaacatgact agaagcggaa aaacaaaagg aatgatggtc
    10201 aaagcaacta ccaaaatctt tgctgaaaaa acctgttctt gtccaaaagg cagaggcaaa
    10261 aatacttgca ggtcatttcc ttcaaaaaag atattataaa tgactgatat actttgagtt
    10321 aaacctaaca taccaaaaag tgccacgtaa taagtaaaga aacctggcaa tttaacaaag
    10381 ttcatagcaa acatagcaaa tccgtaaatc agtaaaaaaa tcagccctga aaaaagattt
    10441 tgagacaaaa gatagatagt taatcgcttt cccttttttc ctttctctct tgctttattc
    10501 gtgagctgtg gattaacata taaaagatta actcgaatta attctaataa ttgtcgctta
    10561 tacatacggt ccatctcctg tcgcttgcct tccagccatt ttcaaataaa tcttttctag
    10621 cgtttcatca ggtgagccat tcaataattc actaactgcc ccctgataaa tcaattcacc
    10681 tttcttcaaa atagccagtt tatcgcataa ctgttgtgcg gtatccaata catgtgtaga
    10741 aaaaatgact gtttttcctt ttgcggcatg agccttcatc atttctttca aatcaaatgc
    10801 tgcttgagga tcaagtcctt gcaaaggttc atccaatacc caaatatctg gatctggcag
    10861 caacgtgccg atcaaaatcg ttttttgacg cattccatgt gaaaaacttg cgattgtttc
    10921 attttgatga ctatacatat caaaaagcgc tgtcaattct gctaaacgct tttctttttt
    10981 ttgtgtgtct aattcatagg cagctgaaat caagtcccaa tattctccag ccgtcaattg
    11041 taaaaaaata tctggggaat caggcacata accgattttt tgtttgatac tcaatcgatt
    11101 ttccgtcaat ttcattccat ctactaaaat cgttcccgat gatggttcaa taatactaac
    11161 taaactttta atcgtagttg attttccggc accattatgt cctaaaaatc caaaaatttc
    11221 cccttgtctt atcgagagag acaagtcttt taatgcttgt tttttcccgt aacttttact
    11281 tacattgatg aattcaatca tttctgtact ccttttgttt gttattactt tttattgtac
    11341 ccttcgttat tggtggagta aatgtcaaaa agagtgcata acaaaaaagg atagaaacga
    11401 ctaggctgct acttgggttg ttctcttcta caggaaaaca ctcttctaac aggtaagata
    11461 tgagtctttg ttttctttaa aatgattcat tttctatctt ttcttgcata aaattcttta
    11521 gtttatcaat acttctcttt cccatctcta gttgttctcc atttgcaaat gttactattt
    11581 cgtttactct gctaatagat gtaatgtttt cagtattaat gatataagct tttaaatctt
    11641 tacataaata ctcatattcg agtgattttt tatatttttt aattgtgccg tttacgagaa
    11701 tctcttcatc tttcaatact aggcctattt tatttttata acctggcatg ctcattagat
    11761 aaaggatttc atcgtaatgg atatagtgat cgctattacc ataacggaca gttgtccacc
    11821 tttttttcgt agcatgttga acaggatagt tttctttttc tttcaataag taactttgga
    11881 tgcttttttt atttttttca taagtgaatt cttttatcaa ataaccacta ggcgtaatct
    11941 ttcgattaat aacagttatt gctttattcg gatgagacgt tagataaaca attttacact
    12001 tttcattctt ttctctaagc atttcgccta gttcgatacc gctataatag gcgttcaaat
    12061 cgatgtctag gaaaaaaata tctgaggaat agatttcatt atttttaatg aattcaacaa
    12121 attgtataac gttcaatccc tgaacgatct caaatttcca aggacttaat aaaattctgg
    12181 attcttccaa aatttctact agcatttttt caaaaaccaa actatcatcc aaaataaata
    12241 tacgcgttac cataaaaagt acctccactc gatattttac tatcaaaatc atttcataca
    12301 acttttcaac atacatgtta ggaataaatt gtaattctct tcacaatctt ttccaacacc
    12361 tttgaaaccg atatcaaata ctttcaggat gctgcttcta aaataaatat caaacaaatg
    12421 aatacatcat gcaaaaaaag ccagacaacc gacgtccttg cgtgtcagct gtctgagcta
    12481 tgtttattta ttttgttctt ttaaaaagaa cgatacacat actgattttt cggagcagag
    12541 actttctcag cgtttgtaac aactacagat gggatttcac gcttgaatgg ttgataatag
    12601 tctgattgga tggttccttc tattttatac cattcatcat ttttaaccgt tactccttcc
    12661 ggcatatgcg tcaacaaacc aaagactcct gaatctgcca cacaatggat aatgccgaat
    12721 cggaacaaga agatatctgt attgctatcg ttcggtgttt ggtaaacaaa tccttcatag
    12781 ctgatttttt tgccaatgaa ttcgctaggg taattataaa ttagctccat aacttctaaa
    12841 tagttttcat ctgtgatctt gatagtttgc ttatccccat acttttcttt caactcattc
    12901 atttggtcta agtagtctga tttgttgaaa taaatactgg tatccggctt taagtattgt
    12961 gtctgcatct ccggatcccc tactgattct ttacttactg ggaaattaaa tcctttggct
    13021 tctacgatcg tagtgtcgag actaactgtt ggaaacaacg tccccacgat tactggcaaa
    13081 gctagcagta cataagcgat tccacgttga taaggttttg acaacccatg gtcatgatcg
    13141 tgctcgtgtg ccttttcttc tgcttttccg tttttgaccc acaaatacag ctgaactaaa
    13201 gccaaaagag cagataaaat cattgaaaga atagctaagt agcgataatg gacattgata
    13261 tattgatcga gtttgccaga aacttgcaag tacatcatca attcgaaata cccagataaa
    13321 atcaaaaacc gcagcatatt ttccctccta aataaataat gtgaatccaa taacgctaag
    13381 ggcaatcagt ccgatcagcg ataaaataaa gcgtcctgta aaatatcgtt tcatcatcag
    13441 tagatttttg atatcgacca ttgggccaaa gaccaaaaag gcagctacag gtgctgtgcc
    13501 gaacagactt aacaaagaag atcctataaa cgcatctgct tctgagcaaa gagacatcgt
    13561 aaaggccaat aacagcatga tgataatggc taaaatcttt gttgagccga gcgttagcat
    13621 aattctagtt ggtaaataag tctgcatcgc agctgcgatt aatccgccaa tgatcaaata
    13681 acgacctgta tcaaaaaatt cgtcgattga atgtgtcaac acatgcccag tttgatggat
    13741 cagctgattt tttggttcat tcttctcact ttgttcttct tcatggacat gatgatggtg
    13801 attttctgct actttagacg tgattttttc tttcaataca gcgtcttttt gaaaataggc
    13861 aagccagaca ccaatcacaa gggcaacaaa aaagctgcct atcacccgcc agcttgccat
    13921 ctgccaagaa ttgccaaatg cgataaaagt ggaaaaaatc acgattggat tgatgatcgg
    13981 agcagtcagc ataaaagcaa acgctgtgtg aactggtacg ccttttttaa caaattgatg
    14041 aacgatcggt acgatgccgc attcacatga aggaaagaaa aatcctaaga tcgaaccagt
    14101 aaaaatagag aagatacgat tttcaggaag ccatctcttc acacgttctg gggtcaaaaa
    14161 tacttgtaag gcgcctgaga taagacagcc taataatacg aaaggtaatg cttcaataac
    14221 gatcgataag aaaatcgtac tcatctgcaa aaccgaattt ggaataaaag aaaacatgag
    14281 tttcctcctt tttatttcta gttcattcgc tttgcaaata tacgctttta ttcaaaaaaa
    14341 aacaagttgc tctgtaaatt tttacacaac tcttattttt taccaaagca cttcaattga
    14401 ctttttctgt tattcccatt aaattaaggt ctcatacata tcacttctat cataaaaggg
    14461 agaataaaaa tgaaacaaac cactaacttg actgaagttc aagacatact gcaacagtca
    14521 tccgttgccg tcatttatct ttcgatgcct aattgcagtg tttgtcacgc tgttcgtcca
    14581 cgactagagg aacttctcac acattatgat attccggcac ttcatttgga tgcatttgaa
    14641 acaccagaag tagctagtaa atttgaagtg ctgactgcgc cagttgtcct gatttttcat
    14701 caaggaaaag aagtctttcg gcaagcacgg ttcatcgact ttaaaaaaat ccgttatcta
    14761 ctagatgaac tgacagcaga agatgattcc ctttcttatg aagaaatctt ccgaacaaaa
    14821 taatcgttgt ccaaacagaa aaaagcgatt gaacaagtga aagttttgcc ttcatttgtt
    14881 caatcgcttt ttatttttat tctgctgtat tttcggaatg cgcatttgcg tcagaatgca
    14941 agaaatagat caaggtttgc aattcattcg tcaaatcaac attttggatc aatacatctg
    15001 acggagcatt caatcgagca gcggtaaagt tcaagattcc tttgattcct gcttccgtta
    15061 actgattgac tacttcttgt gctctttcag cgggtatcgt taaaattgct acttcgattt
    15121 gttggatctt gatttgttct gacatatctt ccattggata aacggggata ccgtctacga
    15181 tgcgcccaac gatttcctca ttcacatcaa aagcacaact gatacgtatg ctattacttt
    15241 gatggaattt gtattttagt aaagcacttc ccaagttccc tacaccgatc agcgcaacat
    15301 ttgtcaattg atcgtcgttt aatgtctttg caaaaaagtg cataagatct tctacatcat
    15361 aaccataccc acgttttcct aattcgccaa aataagaaaa atctcgacgg atcgttgcac
    15421 tatctacttg aacggcttca cttaattcag ttgaagacac ttttttcttt ccagcattat
    15481 ttaaaatcct taaatagcga taatacaaag gcagtctttt agctgtcgcc tttggaataa
    15541 tatgatcttt cacgaaatga cctccacgta ttgtctaatt acatctttga tttctccatc
    15601 atagcagtat ttataggaaa aaatcaattc cattgctcag atattgtgaa attttattct
    15661 ttattcattt atttatcatt tctgcaaatc tcgcagtata atggaattta tggtagacta
    15721 ctaattgaaa aatagttttt tatttgagga gaattcacaa agtagaaaag aggattccat
    15781 gatattatta caagccaatc agattgctcg ccattttggt gcagaagtct tatttgaaaa
    15841 catacattta gaaatcagta caggcgctcg tgtcgcttta gttggcagaa atggcgctgg
    15901 aaaatcgact ttattaaaga tcattgctgg aattgaagca cctgatgaag gaaagatcgc
    15961 taaaaataaa acagcgactc tcggatacct cgctcaggac acaggacttg attccaatga
    16021 aacagtttgg aacgagatgc tgaaagcttt tgaacaagtt agacaaatgg aagagcggat
    16081 gcgcgagcta gagattttca ttagcgaagg tacgccagac acacctgctt atagttctta
    16141 tttaaaagaa tacgaccggc tgcaacacga tttttcagat cgaaacggct atggttatga
    16201 aaatgaaatt cgttccgtat tgcatgggtt taaattcgat tcttcatttt atgatcagaa
    16261 aatcgatact ttatcaggcg gacagcgcac acgtttagct ttagctcgca tgcttttgca
    16321 acaccctgac attttgattc tagacgaacc aacgaaccat ttagatatcg agacactttc
    16381 ctggcttgag aattatctgc aaagctatac tggtgcatta ttgattgttt cccatgaccg
    16441 ttatttttta gataaagtag tcaatgaagt ctatgaatta agcagaagaa aaatgcgcca
    16501 ttacaaaggt aactattcga aatatctaga tttgaaagca gaacagttag caagtgaatg
    16561 gaaggcttat gaaaagcagc aaacagaaat ccataaatta gaagacttcg ttgctcggaa
    16621 ccttgttcgc gcctctacca caaaacgagc gcaaagccgc agaaagacat tagaaaaaat
    16681 ggaccggctg gatcgtcctc aaggggatga aaaacaagca aactttctat tcagtataga
    16741 aaagccttct ggaaatgtag tcttgcaaat cgaagatgcc gctatcggat atgataatgt
    16801 caccttatct gaaccaatca atctagatat ccgtcgtcaa gaagcgattg ctctagtagg
    16861 tccgaatggt atcgggaaat cgacgttgct gaaatcaatc attcaccaga tcccttttat
    16921 ccgtggaaaa gaaacgctag ggacaaatgt caccatcggc tattacgatc aaggtcaagc
    16981 tgatctgcat acaaacaaga cgatcctagc agaattgtgg gatgagcatc ctaccactcc
    17041 agaaaaagag atccgaagtg ctttaggtgc tttcttattt tctggcgaag atgtagaaaa
    17101 accaatccct ctgctaagtg gcggtgaaaa agcacgggtt gctttagcca agttagcgat
    17161 gaacaaagaa aattttttga ttttggatga accaacaaac catttagata ttgacaacaa
    17221 agaagtatta gaaaatgcat tgatcgatta tgacggcaca ctgctttttg tttcccatga
    17281 ccgatatttc atcaatcgga tcgcgacaaa agtcgtcgaa ctctctgaaa atggcagcaa
    17341 agtctatcta ggagactatg attattattt agagaaaaag caggaagaag aagaaatcgc
    17401 cgaattgttg gcacaagatg agccagaatc tgctcctgct cccacgaaca aatctgatta
    17461 ttaccaaagc aaagaacagc aaaagcttat ccgtagcctt caacgaaaaa ttactcaggt
    17521 tgaagaagaa atggcgcgga tcgatgaatg gatcgatcag ttggaacaag aaatggtcgc
    17581 gccagaaaac ctggaagatc acgtaaaact caatgagctg aaccaagatt tagaagctgc
    17641 tagacaagat caagaaacaa aattgacgga atgggaagaa ctaagcttgg aattagaaga
    17701 atatgaaaat taacgaaaaa accaaaacag aaaccattca tgctgttttg gtttttcttt
    17761 ttttatttta tcaaacaaaa attccatatt tacctttttc accaataaga agaccaatta
    17821 ctagtcattc tcactaaagc ttctaaataa tagtaatcac cccaaataca aggtgtattt
    17881 accccattat ttttgggctt attataaaca gactgtgtta aaaagccatc ttcttcttcc
    17941 gttgtagcat atctttcttt caattgtcgc ataattttcc aaacagcaga ctggtataag
    18001 ttcttttctg ttttgtctaa tagacctgat tctattaatt ctaataatcc acaaaccatg
    18061 atcaccatac tagatgtatc tttttcttct ctgctagaat catcaaagat caaatcccaa
    18121 taacaaatgg tatcttctgg caaccgattc ataaaataat tggctaatat tttgcttaaa
    18181 tcaaaatatt tttgttcttt caaataacga taacttaatg caaaaccgta aatcccccat
    18241 gcttggcctc tagcccaaca ggaattatca ctataacctt gatgcgtact tccatatctt
    18301 ggttttccat ctttgacatc catataaaat gtatgataag ttgaaccatc ttctcttact
    18361 aaataatctg ctgcattttg aatatgagcc tgagcagctt ttttatattt ttgatttcca
    18421 gtttcttcac tcgcccaata caataatgga agattcatgc aacaatccat gatcattcta
    18481 ccttgttgtg aaggatcact aggatctccc caagcttgta taactcctgc cttctcccaa
    18541 aaacgctgaa gtaatgtttc tgcagcatca attgaagctt ccttcatttt tcgatttccc
    18601 gttattttat aatctgctac ggttgataaa gaatacaaaa aaccaagatc gtgatgatta
    18661 gtgataattt gacagtcaat cctgtggata aaatctatat ctgctttttc agctgtttgt
    18721 tgaaataaag gatcacccgt cttctcaaat aacaaccaat taattcctgt ccaaaatcct
    18781 tctgtccaac caatattgtc tcttaatgga taacgtcctt ttataggaca ctcgcttggg
    18841 aattgatact gactgttact gatacgtttg attaacctct ccgtgtgtct gcgacaacgc
    18901 tcgatctcat tattccattc tttttccatt aattctttat aacattcatt tatccatttt
    18961 tctggatgta ttatctcttc aaacatcact ttatcaagca tttccccacc agcctttagc
    19021 ataattttag tcttttttta ttgtttttat tttggatagt tagcccggtt gtcccatcaa
    19081 aatcaatttt gggacgattg ttccatactt ctaaactata atcccgatct tgatgagcaa
    19141 ccactcctgt tccgagccaa tgggttcctt ttccaaatgt accctctaat ccaggaataa
    19201 aagtgttttc ccatgtcatc aagtttgtat tgggcaaacc cataatagct gtggattttc
    19261 gtttaatagt atcgtcactt aaacagataa tacctgaaaa gccagcttca ctcaccctat
    19321 agttttcctt gtcttcttct atgattattc cttctttctc aggagaacat tcaatagcaa
    19381 accctgtctc atatagaaca tattctgtat ctaattctac tttgtgtacg cgaatctgcc
    19441 agccttcaaa aggaataagc caagttctga tttttgcctg taaagtaggt tcccatgtag
    19501 aggcaagtac ctctttctta catacaatgt ctcgtacatt atttcgaacg atgaactgtc
    19561 cataggtttt gatgctctca ttcttaaaac tggtcgtgat atatgtgtcc gctcgctgaa
    19621 tccctagcat tgaatccatt gccatttctg ctttcaattg attcgctcgc ggtatcgaaa
    19681 aaccaaattg actagaataa gcaaatttta aatatttttc attggtcaat gtatggaaat
    19741 ttggccctaa ttgtcccgca ttcaaaaaaa atgtatgtcc attatcatgt tgtatgagca
    19801 aattggcttc tgaaagaagt ttagttcctt cacgaatagg cataggcatt tctttagccg
    19861 tccaatactc atggtcttca ggtagcgcca acaataaaaa aatcttattc agccataatg
    19921 gagataacgt actattatag ggttcagtca atgtcaattg agggtaggta taaccaatat
    19981 tcaggatacc tttttcatca aatatttctt tttgcatcca ccatcttata ttccgattga
    20041 ctaacccctt gatttcacct aatttaaaag gcaaaagatc ggcccacaac atagctgacc
    20101 aaaagcttga aactgcaaaa cgataaatca tgcttcgacc aaaaggcaca tttgcaccat
    20161 cttccgcaaa aaaatgaata tagtctctag aaaaatcaat agctcggttc ttatatatct
    20221 ggctaatggg cttttctggt tctagtacgc tataaatcaa accataataa tgaaatgcaa
    20281 aaggattata ataatcttgg cgacctcttg aactgtctcg ataccagcca ttttgaagat
    20341 aacaattttc tatattatca aatgcttctt tcagtgctga ttctttaact ggataaccaa
    20401 atttttggat aattgttccg acaattatct taaaaaattg ccaattacca tctgcacatt
    20461 catattcaaa aatttgcgag aaccaatgaa taatctggct tttttctcct gtatctaatt
    20521 ttttccataa taattgttca tgatgatata acgctaataa cattgcgggc atttctacca
    20581 tacgctggtc tctttcatgt atttctcccc aataatcggg atgggaagga tctgttccag
    20641 cttttattcc tgatagaatt aatttcaacc atcgttcatc taattggtca attgcgggcc
    20701 ccgctcccca taaaacccga gagaatcctt ccattcctgc aattttattt ccatatccta
    20761 ccccttgatg tatataatca atttgtgcgc cacttgctcg ataaaacggc tggagtggtt
    20821 gatttatctt tttaaataag tcaaagtaat cctgtctggt ccttaatagt ggtactggat
    20881 gtttcattgt attttctcct ctttttacta ccaaatagct aattccgact gttctaatcg
    20941 aagtaagcct tcaataaaaa aataatcaga atagatcagt ggcacattat aagtcagttc
    21001 tctatggtat gcttctgctc cgcctccaat gatcccatct tcatccatat tccaatttgc
    21061 atagtgcttt tctgtctttt ggagtatatt gatagcagct tcatgataca tttttgatcg
    21121 tacagaggaa acatatcctg ctaattccag aagaccgcat gcagcgcata ctccagcact
    21181 ggtatcaata ttcgaatctt ttacagcaaa atcaatgaga ggaatataac cagttttttc
    21241 gattttctga ataaaattta ctgctatctt ttctgctata gctagatagt acggattttt
    21301 tgtgtaacga taacttaacg cgaatccata taaagcccat gcatttcctc tgctccaaca
    21361 agaattctca ttgtatcctt gcccgccaag taaccgaata tatttccctg attctgcatc
    21421 aaattctgcg atatgcccgg ttgatccatc tttcctcact agatacttag ctgttgtatc
    21481 tgcatgctgc cgagcaattt tagagaacct cggatcacca gtttccctcg aagcccaata
    21541 cagtaatggt aaattcatca tactatcaat aatcatccaa ccaggtttat ggtcattcca
    21601 tgctactaaa tagttccctg aaatattata gcgtccagca agtaccgtag ctgcatgtaa
    21661 ccctagttgt cgactatgtt tgttttgaga ctgttgataa tgtgcaatag ccgatggtaa
    21721 gaataaaaaa cctacatcat gatgaacgtc tgaaaaatgg tacagggcag attctaataa
    21781 ttgttcttgt tgtattgctg cctctttgaa cttttctcgt tttgtcttgt gaaagagctg
    21841 ccataaaata ccactccaaa aaccattggt ccaccagtcg attcctctgt cctttattac
    21901 gtctgtatat tttccgttgt aagaaatata tggaatttta ttccccattc tgtctaattc
    21961 cgcatctatc ttttcagaag ctacattcaa aatttttctt gaccattcct tcgtctgttc
    22021 attcatggat atcccgccat tcttttaatt tttatgaatg tggagttgct cctagaacga
    22081 actagatggt taacattcgt tatttttttt acttatttgc agctccaatg tcattctcct
    22141 taaatttaga ctgcgcccac acataaatca agaccattgg gatcactgaa gttgctaaaa
    22201 ttagcataat tgcgccataa ttaattggct cacctgtact agaaaccgtc atatttttga
    22261 taattaaggg aaccgtatat ttatctttat ctgaaagcat gactaatgga aatagatatt
    22321 gattccaact tcccataaag ataagtaaac cactagtaat aatcgtaggt gataaaatcg
    22381 gtacagcgat tttcgtaaaa atcacccact cattggcacc atcgattctg gcagcctcca
    22441 tcagtgctgt aggaaattga ctgctatatt gtcgcatcat aaacactgaa gttgtactgg
    22501 caatcgaagg gatgatcaca cctgcataag tattcgataa tcctaaacga ctcataatgt
    22561 aaaataaagg aatcaatgtg gtaaaaaaag gcaccatcct agatagcata actgtattga
    22621 acaacagttt attccccata aaacgatact ttgctaatgc ataacccgcc attgtagaac
    22681 tggctgtagc tgaaactgta ctgattacag caataacaat cgaattccaa ataatcaagg
    22741 gataattata tctcgccatg atggcttgcc agttttttaa tagcatatcc ccaaacttga
    22801 aattgattcc gccacttaaa atttcttgat tactttgcgt tgaagctaca atcatatata
    22861 aatatggcat caaaaatatt aaggcaccaa acacaataat gacgtacgta aaaattctgc
    22921 tttgtatctt ttgtttagtc atttttatca cctccgaatt taaattgaat agccgataat
    22981 ataacagata caaacaccat cgtccaggca atagcagagg cttttccaaa atcaaccatt
    23041 tcaaaacttg ttttatataa attgactcct acgaccaaag ctgaattttc tggtccattg
    23101 gaagtcccaa agaatatatt tgggatattg aaattaccca agccattgat agtggctaaa
    23161 actgtggcca ttaaaatgat tggctttagc atggggatcg ttaataaaaa gaattgccga
    23221 aatttcgatg ctccatctat ttcagcactt tcgtatatct ctttagaaat cccttgaaga
    23281 ccagctaaaa ataaaatagt gttatatcct acactaagcc aaatcatcgt gatgatcatt
    23341 gatattcgta tccaaaaagg atttgttaac cactgtacac cgttaattcc tagcgcattc
    23401 aaaaatccat tgaataaccc agtcggattg aaaaaagtca tgaatacgga agctacagcc
    23461 accgttgatg taatggttgg aatataatag acagttctaa aaaatccttt tccttttaac
    23521 tgtgctgaat tcaataaaac agcaaagtaa atagctaata gcatcgttat tggaattgat
    23581 cctgccatga taatcaaaac attcgtgtaa gatttaataa acaatggatc tcggaagata
    23641 gctagataat tgtcaaatcc aacaaattca aatgagtagc caattttcat aaaactaaaa
    23701 gcaaacgaga taatgatggg aatcaaaatc gtcacaataa agaaaataac aaaaggtgtg
    23761 accaatccat aagcactttt tttatgagac gtatctgttg cttttttctt gctgttcttt
    23821 attgtcttgc ttggtaacga agattgcatc atcgttaagt cctcctaata ttttttaatc
    23881 accagttaat tttacgccgt acttatgagc aaaattttct gcttctttta gatatgaatt
    23941 ttcaaaatca cctgtttgcc aatagttata tgcagcggta gtcaaataag acgtagcatc
    24001 tgaataagtg gctggtaaaa cagtatttga tgtattttca ttgattttat tcaatagttc
    24061 atagtatttt tgtcctcctt agtagtcaaa ctttttctca gctgcttctg tttgataggc
    24121 caatgagtta gatgtagcca cgcccagctc cagtgcgttg gctaagcatt cttcatctgt
    24181 cagcataaat gtaagaaatt gttgtgccac ttgtggattt ttggcatctt tagggacata
    24241 aaaacttgat cctcctgata ctgcaccttt tcctggattt tcttttgaaa aaggaatcag
    24301 tggagccatg cgccatttgt cagatgcatc aggaaaattc aaagacatat tcgtagcata
    24361 ccagccgcca gcaacaaaca ttgcagattc ttgaaatgct ttctcagcat cttgtgcacc
    24421 gtagaaatgt acaatatctg agtcgatcat ttctttgatt aactttgcag catgtttcgc
    24481 ttctttagta ttcagacgga tatttccttc ttcatcaagc aaagattgat tctgctgggc
    24541 tagcatgttg ataaacaatt cttggtcccc agattctggc aaggcaattc caaaactacc
    24601 agttttttct tttaatgctt ttgccacctg gatatattct tcccaagaac tgatttcttc
    24661 aaaatctaca cctatttcag caaatttttt tggttgataa taacaaagtg ctggggtaaa
    24721 atcactagcc caaggaataa tcgtttcatt actcgtttgt tgacgcaaaa tattcaattt
    24781 ttgatcataa aactgatcgc catatttgtc ataaaatcca tattcatcag cactataaaa
    24841 agcatcttga aatttttcca gcacacctgc tgctgaagtg tctgccatgg agataatatc
    24901 cggcatatct tcgtgtgtta ccaattttgg ggtgatcatt tgtactgttg ctgttcccga
    24961 agctacattc acaattttta agtcaatatt tgctccagtt ttgcggttat agatttttgc
    25021 agcattttca acatagtttg tcagtttgcc gtttgcgaca tatacttcta atgtagtggc
    25081 tttttttatc attggatctg cgatgtttgc tgttacttct tcgttagttt ttccacatgc
    25141 acttaagctg aataataggg taatgtttag caaagctatc accaatttgt atcttttttt
    25201 catgtctatc ccttctttct tttcaagttc ttatataaaa cgctttcact tatgtatatt
    25261 aacggaatta gtaacacaaa tatttatata aaaaaatatt ttacttgtcg ttttggcttt
    25321 tcatttttgt tataatagtc attaattata aatagaaagc tttttatata aaaagagaaa
    25381 ggaaagtggt tcttttgtta acaaacaacc aatcctccaa tcttgtcaaa aaaacactaa
    25441 cctattccat agatacccat cttcatttat ctgctgctcc ctattttcga ctactaataa
    25501 atgaaagcgc taatttatat gctgaatttg cacataaatc tatagaacta gataatcctt
    25561 cccttttatt cattgataaa cagcaagaag tccaaatctt ttctactcaa aaggaaacac
    25621 aaacttttat cattatccag ttttattttg atgagcaatt attagcacat attacgggac
    25681 aatctttttc tatagatcaa gaaataacat ctatcattac ttttctgaaa aatgaacagt
    25741 tcaaaattga ttatctaaaa catagtaagc cagctatttc ctatgatcag gaaatcaatt
    25801 cttttttcat actatgccaa cagatgagca ttcatttgct ttccttatta gttacttatt
    25861 gtctgcaaaa aattcaattg tcttccttac caaggcatta tcaacaggaa cttgctttat
    25921 tgacaatacc ttcaaatgag aaagtcattc ctaaaaaaaa gcatattctt tattcagatg
    25981 aattagttga tccaatcata cgatatttag aagaacatct ttcagaaaat tttttgcttg
    26041 aacaattagc ccaaattttt tttatcagtc cagccagctt aaaaaaacat tttagaaaag
    26101 tgaatggaaa aagtgttatt agctatttta aagaactaaa aatggaaaaa gcaaaacgtc
    26161 tcgtgctaga aaatgaatta acctatacag aaattgcaga tatattagga tttcattcga
    26221 tccatcattt ttcttcagct tttaaaaaat atacagggtt atccccttca aagtattatc
    26281 tatccttaaa atagaaaaaa atttttaggt tttatccaca aattatttct ctatattttc
    26341 tgtctattca aaataaacaa taattttccg gcacaattat ttgctgtttt ttaccataac
    26401 atagtacgat caacgtagaa aaggagatgt ttttatgaaa gttgttgtca ttggcggtgt
    26461 agctggcggt ccttcatttg ccactcgttt ccgtcgattg aatgaagcgc acgaaatcat
    26521 tatctatgaa cgcggagaaa atatttctta tgcaagttgt gctttgcctt attatttagg
    26581 aggtgtgatc actgaccgtg actcgctgat cgaacgtaca ccagaaatat tgaaaacaaa
    26641 aaacaacatc gatgtcttta ctaaacacga agtaacagca atcgatcctt ctactaagcg
    26701 attaacagtt aaagacctat ccacaaatga agaaataaaa acagattacg ataagttgat
    26761 catctcttct ggtgctagac cagattatcc ggatattccc ggagtttttg aagcagaaaa
    26821 cggctttgtc ctccgtagtg tgacggatgc ggatcgaatc aaatcgttcc ttgaagaaaa
    26881 aaatccacaa catgtcgtca ttcttggtgc aggtgttatg ggtctggaat tagctgagaa
    26941 tttcaagcat cgcggcttag acgtgacttt aatcgatcaa ttgccacaag tcgctttccc
    27001 ttatgatcca gaaattgcta atttagttta tgacaaattg ctgaaagaag gattagccgt
    27061 tcatttagaa acaagagtta ctgagatccg tgataaaggt cgagaaatag tattatcaga
    27121 tggctccgtc ctttctgctg atatgctaat ttttgctgtt ggtgtttctc cgaagaatga
    27181 agtggtgaaa gcaaccggca tacaattatc agatacaggt cagatcattg ttgatgacca
    27241 gttacaaacc aatctgccgg acatctatgc gattggcgat attatcgaaa cgactagtgt
    27301 agtgactggt cagccgatcc aaagtatgct ttccagtgcg gccaatcgtc aaggacatat
    27361 gctggcagat attttaaatg gtacgcctat gcgctatcgc ggatatattg gtgcaggtgt
    27421 cgcaaaaatc tttgatcata cagcaagtta tgcgggaatg acagaacatg aattaaaagc
    27481 atcaggcata acaaattata aaactgtttt tatcactccc tttgaccatg cctatttcta
    27541 tccagaagct acaagattaa atctaaagct gatttttgat gcagatagcg gtcgtatttt
    27601 aggtggacaa gcatttggag aaaaaggtgt cgataaacgg atgggagaac tttctgtagc
    27661 aatcaccgga aacttgacag tctttgattt gcctgatttg gagttgcctt actctccacc
    27721 gtattctact acccgtgacc cgttgaatat agctggttat gtcgcaatca atcaaatgac
    27781 gaatatcgta gaaacgatca aagcaagtga tatacccgaa aacgatttga aagaagcgtt
    27841 ctttttagat atacgtgaac ctaataaagc accttctggc agtatctcgg caacaaaaaa
    27901 tattccaatg aatgagttac gagatcgaat caatgaaatc ccaaaagata aaaaagttta
    27961 cattactttc agaagaggat tgaatactta tacttctgcc cgaatcttgg caggtttggg
    28021 tatcaaagcg attttgattg aagaataaaa aaacgaccgc ggtgggtagc cgcggtctag
    28081 gagttatttt tacttgagga gtaaaaatga aaaagtatat agggttgttg gttggtatgt
    28141 atatagaata gaagataaat gtgaagaaat tgtgcattat ttcttcacat ttattaggtt
    28201 atagtttaag aaagtttaaa cattgcgcaa tttaattatt ttagctgttt cttttcataa
    28261 aaaaacatgt tgtgactctg agacaaatca tagtccatag tgatgtctct agagtaacta
    28321 cgcctaatat tacgaggcat catattaatc tatcagcact agtacctaaa ctagcatccc
    28381 tttcgaatat tttttcttat ataataaagt ttgctttcac tcctctaatc tcaccaaatc
    28441 gactggcttg cgttgtgtga tactaggaac tgattggttt agaacgactt ttctattgta
    28501 atcatatttt tcgccatcct cgttgtcttc taatccttca atgaatgatc cctaatgtgt
    28561 gtattaaata atttaatttt tttgttccta tttatttaa
//
LOCUS       DASHWW010000029        27637 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.029, whole genome shotgun sequence.
ACCESSION   DASHWW010000029 DASHWW010000000
VERSION     DASHWW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.029"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            121..768
                     /locus_tag="U2R64_001476"
     CDS             121..768
                     /locus_tag="U2R64_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEM8918299.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            852..1796
                     /locus_tag="U2R64_001477"
     CDS             852..1796
                     /locus_tag="U2R64_001477"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEM8918300.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1931..3382
                     /locus_tag="U2R64_001478"
     CDS             1931..3382
                     /locus_tag="U2R64_001478"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEM8918301.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3403..4239
                     /locus_tag="U2R64_001479"
     CDS             3403..4239
                     /locus_tag="U2R64_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEM8918302.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4239..4898
                     /locus_tag="U2R64_001480"
     CDS             4239..4898
                     /locus_tag="U2R64_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8918303.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5024..5713
                     /locus_tag="U2R64_001481"
     CDS             5024..5713
                     /locus_tag="U2R64_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918304.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5719..6675
                     /locus_tag="U2R64_001482"
     CDS             5719..6675
                     /locus_tag="U2R64_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HEM8918305.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6719..7231
                     /locus_tag="U2R64_001483"
     CDS             6719..7231
                     /locus_tag="U2R64_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918306.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7487..8035)
                     /locus_tag="U2R64_001484"
     CDS             complement(7487..8035)
                     /locus_tag="U2R64_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8918307.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8124..9305)
                     /locus_tag="U2R64_001485"
     CDS             complement(8124..9305)
                     /locus_tag="U2R64_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEM8918308.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9541..11049)
                     /locus_tag="U2R64_001486"
     CDS             complement(9541..11049)
                     /locus_tag="U2R64_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEM8918309.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11208..11399
                     /locus_tag="U2R64_001487"
     CDS             11208..11399
                     /locus_tag="U2R64_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918310.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11602..12519
                     /locus_tag="U2R64_001488"
     CDS             11602..12519
                     /locus_tag="U2R64_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HEM8918311.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12512..13585
                     /locus_tag="U2R64_001489"
     CDS             12512..13585
                     /locus_tag="U2R64_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918312.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13733..14251
                     /locus_tag="U2R64_001490"
     CDS             13733..14251
                     /locus_tag="U2R64_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918313.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14232..14624
                     /locus_tag="U2R64_001491"
     CDS             14232..14624
                     /locus_tag="U2R64_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEM8918314.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14700..15635
                     /locus_tag="U2R64_001492"
     CDS             14700..15635
                     /locus_tag="U2R64_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEM8918315.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15768..16547
                     /locus_tag="U2R64_001493"
     CDS             15768..16547
                     /locus_tag="U2R64_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEM8918316.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16540..16857
                     /locus_tag="U2R64_001494"
     CDS             16540..16857
                     /locus_tag="U2R64_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEM8918317.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17101..18711
                     /locus_tag="U2R64_001495"
     CDS             17101..18711
                     /locus_tag="U2R64_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8918318.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18868..19716
                     /locus_tag="U2R64_001496"
     CDS             18868..19716
                     /locus_tag="U2R64_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8918319.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19947..20426
                     /locus_tag="U2R64_001497"
     CDS             19947..20426
                     /locus_tag="U2R64_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918320.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20459..22687
                     /locus_tag="U2R64_001498"
     CDS             20459..22687
                     /locus_tag="U2R64_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8918321.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22816..24459
                     /locus_tag="U2R64_001499"
     CDS             22816..24459
                     /locus_tag="U2R64_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEM8918322.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(24532..25077)
                     /locus_tag="U2R64_001500"
     CDS             complement(24532..25077)
                     /locus_tag="U2R64_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEM8918323.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25100..25585)
                     /locus_tag="U2R64_001501"
     CDS             complement(25100..25585)
                     /locus_tag="U2R64_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8918324.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25575..26387)
                     /locus_tag="U2R64_001502"
     CDS             complement(25575..26387)
                     /locus_tag="U2R64_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HEM8918325.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26526..>27637)
                     /locus_tag="U2R64_001503"
     CDS             complement(26526..>27637)
                     /locus_tag="U2R64_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEM8918326.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         9050 a         5028 c         5526 g         8033 t
ORIGIN      
        1 tctttttctt tatattttca taataaaagt ttggttcttt aatttttaaa catgacagaa
       61 aattttttct tcgttatact tgtaatagaa tactatttta taacaaaggg gatcgaatca
      121 atgaaaaaaa ctgttattta tactagttta tttgcagctt tgtttttagc tgcttgtcaa
      181 tcaaatacca atcaaggcac atctgggaat acgtcttcca gtagcgaaca gcgctcttca
      241 caggtatcgg actcctcaac aaaagcaagc acatcttcgt ctagccagac aaaaagttct
      301 agtgaagcaa gtactcagtc agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc
      361 caagataaat acccagatac tgcaattact agtttggaat tagatagtga ttggggatct
      421 tacttctaca agatagaagg tgtcgatgat caaaaagaat acgaagcaag aattgatgct
      481 caaaatgaaa aaatggagac agagaatcca gaaactctag atcgagatga acaaaatggt
      541 caaaagaaaa aagaagatgg tctggatgtt gataaattga tcacgattga ggaagcagca
      601 aaaatcgccg tcgacaaagt aggaagcggt acggcaacag attgggattt ggataaagat
      661 ttaggtacta cttattggga agtcaaagta aaagacggca atcaaagtac atcagtcaag
      721 atcaatagcc aaacaggcga agtactgtca actgaacaag atgattaaga atttcttcgg
      781 aaaacaagag ttgatttttc ttttagtcat gatacactag acaaaataac ttgtttgaag
      841 gagcgattta cttgagttta gaaacgacct ttgccaatca tatctttgcc aatcctttga
      901 tgaatgcatc tggtgtccac tgcatgacta cccaggaatt agatgaactg gctcattcag
      961 aagcaggagc atttatcact aagagctgta cgatcaatga acgaaaagga aatcccgaac
     1021 cacgctattt tgatgttcct ttagggagta tcaattctat gggacttcca aacttaggtt
     1081 tttcttatta tctagagtat gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac
     1141 cgttattttt ttccattgcc gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa
     1201 tagaaaaaag tgggtttaat gggatcactg aattaaattt atcttgtccc aatgtgcctg
     1261 gaaaaccaca actagcttac gattttgagg ccacttatga aacactgaaa gaagtattca
     1321 gcatcttttc taagccgcta ggaatcaaat tgcctcctta ttttgatttt gctcattttg
     1381 atcagatggc tgatatcttg aatcagtttc cattgaccta tgtcaatgct atcaacagtg
     1441 tgggcaatgg tttgtatatc gatacagaac aagaagcagt agtcatcaaa ccaaaagaag
     1501 ggttcggcgg cattggcgga gagtatatca agccgactgc tttggcgaat gttcgcgctt
     1561 tttatacacg tttgaaacca gaaatccaaa tcattggtac aggtgggatt cggacaggac
     1621 aagatgcatt tgaacatctg ctatgtggcg caagcatgtt acagattggt accgagcttc
     1681 ataaagaagg gccggaaatt ttttctagaa tcataaaaga attaacgcag attatgtcag
     1741 aaaaaggata tacgtcaatt gacgaattta aaggcaaatt acgcaccatt tcatagcaaa
     1801 gagacgaagg tcatgattga tcttcgtctt tttttataaa aaacactcgt ctgttcattc
     1861 ctgtgcaagc gtactcattg tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa
     1921 ggaggataat atgaatgatg caacagaatt agcaaaagag cttaaagaaa aagaatttag
     1981 ttttcaagaa ctagttacgg atatacagaa aaaaataaag aagcaaaatc atgaattgaa
     2041 tgcgtttgtc gcgcttgaac cattcgagag taattcccac gagctattga ttccccagtc
     2101 agaaaaaggg ccattggctg gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa
     2161 gggatggcta gctacttcag gatctcgttt atttgaaaca caccgagctt ctcatacatc
     2221 taattatgtg cggcaagcag aagcgatagg tctagttcct tttggacaaa ccaatgcgcc
     2281 agagtttggt ttcaaaaata ttacagaccc agtcatctat ggcccagcaa gaaacccttg
     2341 gaaccttgaa tgtacaccgg gcggatcaag tggaggagct gctgctgcag tttcatcagg
     2401 aatcgttcct ttagctggtg ctagtgatgg cggtggttct attagaatac ccgcttcgtt
     2461 ttgcggattg attgggctga aaccttcgcg agggacgatg ccagttggtc catatgcttg
     2521 gagaggatgg caaggagctg ctattgattt cggcttgaca gtttctatga gagacacgga
     2581 ggctttattt tatgggatga gaagtatcca ttccggtgcg ccatatcaag tatcgccagt
     2641 tgagtggcaa acacatccaa gaaaaaaacg gttgaagata gctttttgtg ttgattcacc
     2701 gatccactca cagattagtg aagaggcagt acttgctgta aaaaaagctg tagatttcct
     2761 tggaaaagaa gggcatgatt tgacagagat tccttaccca ctagatggtc gtaaactgat
     2821 cacgtcttat tatcagatga atggcgcaga aacagcagca atgatccgct cgattgaaac
     2881 aggcatccag cgagctgtca gaaaagaaga acttgaaccc atttcttgga ctttgttcca
     2941 atatggtcag aagctctctg ccgctactta catcgattct ctgcatgtat gggatgaagc
     3001 agcaattgtc atggaaaacc tacatcaaga atacgatcta ttcctttcac caacgactgc
     3061 atttaccgcc cctaaaatca gcgaagattt gcaaagtgat gcgataagag cacagatgga
     3121 acacatcagt gattgttctg aagtagaagg tttagacgtt gtttcttcca tgtttgagga
     3181 gagcttgaag atcacacctt atacacagtt ggctaatctg actggacaac cagcaatcag
     3241 cttgcctact catttgacaa aagaaaacat gcctctagga atccaattta tggctgccag
     3301 aggaagagaa gatttgctat ttcaaatcgg ctatctattt gaagcaaatc atcagttcca
     3361 tttaccaaat ccatggaaat agcagaaaca aggagaagaa gaatgaagaa aaaaagattg
     3421 tttgctctaa taactagtgc cttttttatt ttaagcgctt gcggtacagc tgccgctaat
     3481 caggaagata acagctggag taatgtagaa aaaaagaaag aattagtagt agcgacttct
     3541 ggcacactgt ttcccgcatc ttattataat gatcaaaatg aattagttgg ttatgatgta
     3601 gatttggcaa aagaggtggc taaacggtta aatgtcaaaa tctcctttaa agaatacaac
     3661 gtggatggac aaatcacttc tgtttcaaaa agagaatcag attttgctgc gaacgatttt
     3721 ggtatcacaa aagaaagaga aaaaaaattc tccctttcag agactttcaa atattcattt
     3781 gacagtatga tcgtacgaaa aaaagatgat tcaggaatcc actcacttga agatcttaaa
     3841 gggaaaaaag cagctggcga acccaatact agctatatgc gtttagcgga aaaacacgga
     3901 gctaaattag tcacatatga caatgccacg aatgatcagt atttaagcga tgtagcaaat
     3961 ggtcgaacag atgttattct aaatgattat tatctgcaga aaatggccgt atctgcttta
     4021 ccagatatcc ctgtaaaaat actggagaac gtttatttca atgaaaacga aagtggtttt
     4081 ttattgaaag aaggaaatga tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg
     4141 aaagaagatg ggacgacaaa gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc
     4201 aaaccgaaag aaacgatggc tgagtcggtg agtgagtgat gtactttcct ctaattgatt
     4261 tttccctcat gtggacttca cttcctttcg tactgcaagg cttggtatac acattaggga
     4321 ttggcttcgt gtcgtttctt ttaggaaatc tggtagggtt gcttttgaca gttttaggtc
     4381 ttttggattg gctgcctctg aatgtattta ttcgttttta tttatcgttc tttagaggca
     4441 ttcccgcact agtcctgctg tttctgttat attttgggtt accttatcaa ttaagtgcct
     4501 taacggcttc agtcatctgc tttacgatta ccagcagtgc atttattggt gaaatctatc
     4561 gaggatcact agcaggcgtt tcttcaggtc agtgggacgc tggtttagct tctggttttt
     4621 ctttctttgg ggtattgaaa tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg
     4681 cactcagtaa cgtagctatg gatctagtga aaggtacttc gttagcagca acaatcacag
     4741 tgccagaaat atttcaaaaa gcaaagatca taggcggtcg gacattcgat tatttttctc
     4801 tctatatttt agttgcactg atttattggg tcatttgtat cgggatcgaa aaagtgcaac
     4861 agtatttaga aaaacgttct atgcatcagt caatctgaaa aatagaaatg gtgctagcgt
     4921 ggctggcacc atttctattt tttgtttctt gtatattctg cctagtattt taaaaccatt
     4981 tcatgtaaaa tgtaaatcga aaatatgttc ggaggtagaa aacatgaaga ccccgctaac
     5041 catcgaaata gaatcctcgt tataccaata ttgcatcgag caaggcggct tggttgtaga
     5101 agaagtcacg atgcctgatg accaaggaat tgtagatacg cttagctgct tgacaaaatt
     5161 tgatggaagc cgagaatggc gatgctatga gctgaaagtg acaaaagcag attttcgctc
     5221 tacagccaaa ctgtcatttg ttggacatta taattatttt gttttaccaa gtaaactata
     5281 tgaagaagta aaaactgaaa tccctacagg aataggtgtt ttagtgtatc gtccgtacac
     5341 ggttgaagag gagatgcctg cctctggtac atttctgatt gcgaaaaaag cagcaaagaa
     5401 agagcttgct gtaccggaag aagctttgac aaaccgcttc atggcttctt tattcaggga
     5461 agtaagaaaa gcaaagcaaa tggagcgagg cgtaaaatat tttccaacag atcaattgta
     5521 caaagaattg aaaagacgtt cagaaaatca agatccattt tctaacgaac gatattatga
     5581 acggttttta gaggaaatag ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc
     5641 gcttcagcat gattatgaat atttgaggca acaacagcag atccgtcggt tgcctacaga
     5701 gccattggag tgaaaaatat gtactatcct tatttaagag gaaaacaatt tgacctatta
     5761 gcattaaaag aagcactgtc gcgaggattg ctctccaata aaatccaacc agtgatcgaa
     5821 ccagtacgtg attccgctac gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat
     5881 cgaatcgctg tgatccaaaa tccccaagta ggacaattca aattattcga tcagcatgtg
     5941 cacagttgga cagtcaaaga aaatagctct gtcgtccctg cacagatctt aacgccagaa
     6001 aatctcagtg aagtactgga ttcacctcca gcgtttcttg ttttcgatgg acagcactac
     6061 ccaaaagata cagaggtgtg gaaacagttg gcaggagttg attcgaaatt tttgatacca
     6121 gatactagtc gctttcgcat ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt
     6181 caaacgagaa agcatgttga aagttatgca gataaaacag atgacttttt tagtgatgac
     6241 tatctttttt tccacgcaga cggatatatt ggattttctg atttcacgat cgaaggtagc
     6301 cgttatttcg ataaagggtt ccctagccga gcgcttgcta tccatctaac gtatattgat
     6361 gcttacggca atatacgcgt gaaacatttt gtctctgaca gtaacgactc tgctaaagac
     6421 caagcattga agtttcttga agcaggagat aaaatgaaaa aatggatcat gcgtcaccat
     6481 catcaactct tgattacttc aggaatgatt gaattattgg ctctttacca gcaacaaaaa
     6541 ttccctggac tgggagtgtt gaaaaagtgg tcacttatgc atcatttgga acttattagt
     6601 cacctgctag atcatccaaa agattggctt aaatattatt caaaagttca ggaactatat
     6661 gaagtgatcc aatgattaga taatgtaaat gaaaaaggaa tagaaaagag gaaactggat
     6721 gtatattcgg caaacaagga aagaagaagt agaagaagtg gtagaaatca ttaatgccgc
     6781 agcggatttc attgcttcgc aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa
     6841 agaaacgatt ttgaacgata ttgaaagaaa agaaagctat gtattaatag tggaagatca
     6901 aattgctgga acagctgcat tagtctcaag cgtggatccc gtttacacaa aaatagatgg
     6961 tagttggaaa gaatcaactg gtccttattt atcgattcat cgtgtcgctt tagcagaaag
     7021 tactcgagga aaaaaactag caaaaccgtt cttagaacat ttgttgacga ttgcagccag
     7081 caaaaatatc caagatatcc gtatcgatac ttatccagct aatgaaccga tggaaaagac
     7141 catctattct gctggattca cttatcaagg gatgattgaa tttccttttg aacacggcga
     7201 aagaaaagca tatcaaataa tcatcaattg actataaaat catctgagca aagataaaga
     7261 cattaacact actgaaaaaa acaatcatat gatagccaag aggttgtaac agaagtggcc
     7321 agcttcaaaa aacaagaaag aatttccgaa aatgcttctc aaatttttgt ggaattttag
     7381 cgtattttac gaaatagctg ctttctgaaa ctcccttcat cgagaggtcg tgacatagct
     7441 tttgtcacga cctctcggct tatcctacga gtattattcg atacatttat atcaataatc
     7501 ctttttttat tttatctgca gcttcttgga acgctccatc gtttgacacg actaaaagtg
     7561 aggggatagc tttcaaacgt ttcaactgtg ctaaatcttc tacataaacc gccagtctgg
     7621 ctgaaatctg ttcagatgaa tctccacgtt ttttcaggcg cgattgcaat gtttctttag
     7681 agatcgtaat aaagatagga cggactaccg tcccgaaata ctcatataaa tgccaaaaac
     7741 catttgctgt caaaacggcg taacaatttc ctactgtcag tttcttttta atttctgctt
     7801 tactggaacc atatttatgt tgagcatatt ggtcccactc tgcaaactca tttcccttga
     7861 tcatctgatt gaatgtattg tcagaaacaa aataataatc ctcttgatct ttttccccag
     7921 gtcttggtga tcgattcgtg taagtaatga tcttttgttc cggctgaaaa atagcttctg
     7981 cgagtgaagt ttttccagaa ccagaaggac cgataaatac atagcaataa ttcattgtca
     8041 tttctccttt gatgattgaa caagtgaaaa agctttggaa aatatttcca aagcttttaa
     8101 aagtaacttt gcttttttgt atattatacc agcaagccag tcacaatagc acttaaaaag
     8161 ctgactaaag tcgctgttag caaaattttc aatccgtgtt ttgcgacaag atttcctttt
     8221 tcttcattta atcccttcat cgcaccagaa atgatcccga tagaagagaa gttggcaaat
     8281 gaaacgagga agacagatat aattgctgtt gtacgctcag taaaatggaa attaccattt
     8341 gctaattctg tcatagcaac aaattcattt gtaaccagtt tagtcgccat gatactaccg
     8401 gcatccactg cttctttcca tgggattccg ctgatgaagg caagaggggc aaagatgtaa
     8461 cctaggatct cttggaaagt gatgccgaat atcccgtgga agatagcatt gatcatggca
     8521 atcaaagcaa caaaaccgat aagcatagca gcaaccgtga tcgccacatg gaaaccatca
     8581 agaatgtatt ctcccaacat ttggaaaaat gtctgttctt tgttttcttc aatgatcagc
     8641 tcatcttctt tttcttctaa tacataggga tttacaattg aagccagaat ataaccgcca
     8701 aataagttca aaacaagggc agtgatcaca tatttagaat cgatcagtgc catataagat
     8761 ccgacgatcg acatagaaac tgtagacata gccgatacac tcatggtgaa caaacgtttc
     8821 tcagatagga agggtaattc cttttttatg gaaataaaaa cttccgattg tcctaaaata
     8881 gcagaagcta ctccattata agattccaat ttgcccatcc cgttgatttt acttaatcct
     8941 agaccaacag ctttcataaa taatggaaga atcttgatat agcgtagaat accgataata
     9001 gcagaaataa atacaattgg catcaatacg gaaagaaaga aaggtgcact tcctttattt
     9061 gctacaccgg caaaaacaaa gtcaacacct tgcccagcaa aagcaagaag atgatcaaac
     9121 atttttgcca atacagaaac aaccgctgta ccaaaagttg tacgtaataa tacgaaacca
     9181 agaacaagct gtaaaacgaa catcacaatt agtggtttca atttgattgc ttttttgtta
     9241 ctgctgatca aaaaagcaag ccctaatgtg acaaataaac caataatacc taataaataa
     9301 ctcaaataat cactcctatt ccaaattccg ttttatttta cctgttttgc aaataaaata
     9361 ctaatcttta gtgaaatttt cattactttt ttagagtgaa acgcattcat tttccattag
     9421 aaaataaagc gaacaaaata aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa
     9481 aaaacgaaac tatcgattaa gctaatagtt tcgttttcaa catttataag taaacttttt
     9541 ctattggtaa tatagatttt cggaagggta gacaggtgcg caggtaatat cgattcctag
     9601 ttttttcaat gtttgttcat catttttatt gaccatcaca gtagagtggg cttgtgctcc
     9661 ctcaagttca gctagtttat cataagcaac ttgagcgatt ggattcgtta ctgcactgat
     9721 tgataaagcg atcaagactt cattgatgct tagtgcatcc aaagaggaat gaagtgtctt
     9781 tgatttcaat ccttgtattg tttcaagaac taatggtgac aataaaggaa tgtcatctgc
     9841 gatatgggct aaatgtttta ctgcatttaa gataactgcc gctgacgcat ccatcaatga
     9901 acttgtacgc ccggtaatga tgacttcatc tggtaattcg attgcaatca cagcagaagg
     9961 atcttttgta ggactttgcg cttgaatctt atctgcatag tcatgggcag ggactaccac
    10021 gtttcggtct tcaggacgta aaccgacttc ttccataatc agtttgattc gattaactgc
    10081 ttcttcgtcg atcaatcctt ttttgaagtc gcattctgtt tggaaataac gacggatgat
    10141 ttcttgttta gaggcttctt ggacaacggt atcatccacg atcccaaatc ctacacgatt
    10201 cacacccatg tcagtaggag attgataaac agattcttta ccagtaattt tttcaataat
    10261 acgtttgatt acaggaaatg tctcaacatc ccgattatag ttcacagcta ctttattgta
    10321 ggcatcaaag tggaaggaat cgatcatatt gacatctttt agatcgactg tggctgcttc
    10381 ataagcaatg ttcagcggat gtttcaacgg aacattccat actgggaaag tttcgaactt
    10441 ggagtaacca gctgcatgtc ctttttggct ttcatgatac agttggttca aggaagtagc
    10501 gagctttcca cttcctgggc caggagctgt cactacaacg attggtttag ttgtttcaat
    10561 atactcattt tttccaaaac catcttctga gacgattttt tctacgttga ctggatagtc
    10621 ttcgatttct gagtgtttat agaccttgat gtttcgtctt tctagtttat tgataaagac
    10681 tttcgtggca ggctgtccac tatagcgagt gataacgaca ctgttgatta ataagccata
    10741 accacgtaat tcatcgatta accgcaagat atccatatca taagtaatcc cataatcacc
    10801 acggatctta ttacgttcaa tatctccagc atagacgcaa atcagtattt cagcttgatc
    10861 tttcaatttt tgcagcaatt tgattttcgc atcttcttca aatcctggaa gtacacgttt
    10921 cgcatgcttg tcgtcaacta gcttcccacc aaattctaaa tataatttgt catagtggtt
    10981 cactcgttcc aaaatatacg ctgactgctc ttcaatatat ttttctgaat caaaaccaat
    11041 ttttttcact aggttccctc cttaagtact aaagcatttt ttcatttttt tgaggattcg
    11101 tcaactggaa gagcgaaatt cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct
    11161 agatagttat tcattggtat gatagttttt gataaggaag gtgctacatg aaaaaaagac
    11221 agaaaaagaa aaacgcatat aaacactata tccgttcgat ttttaccggt tatgaaagaa
    11281 tgcttgaaga tcccgaattg gaacaattga cgtttactta tctaaacgaa gaaacgcagc
    11341 taactcgtga tgagcatcag cgcattcatt tcacaacaag agatctgcct agtaaataaa
    11401 aaataagata aaggtcatcg gattcgattc tgtcctatca gatggaaaga ctagttgatc
    11461 gaaaaaaagg ctgtaccaaa ttttggtgca gcctgtttta tggagcattg cccgctcttt
    11521 tttataacaa ttttttacag aaaatggtac tattgaagta ttaataagtg aaaaacagat
    11581 gagtaagagg aggcaagtag tatgaaagag ccagatacaa atgcaaatta tgagccagac
    11641 gaactagagg agacgaatgc ggatcaggat acaggacaag aatcgtcttc tttttacgat
    11701 atcaaagaaa aagcaagcat gaatctttcc caattattag aagacttaca ggcttttgaa
    11761 aaagctgtcc gcgaagaaga tatccctgag atctaccgtt tatacaatgg ccgattgaat
    11821 gaagaattaa aaagaagctc aaatgaaaat cacgagatcg atcaattgct gatgcgtaag
    11881 atccatgatc gttttttaca ggaatttcct tttatggaac aagtagaaaa catctcgcca
    11941 acgatgagct attacaaaat cggcacttat taccatgatc ggcccacggt cggtattgat
    12001 gcaagtctgc cagaaatttt tgttttgcct aagatcgatg aagagtggga gaaatattcc
    12061 caaccggagt caacggacta tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact
    12121 gctcagacag aaattgaacg tttagatgaa caaataaaag aaatcaatcg acaaatgact
    12181 gatttgaacg acaataaagg attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa
    12241 ttagagaaga agaagcaagt actatctaat gaaaaattag gctggcttcc ttatattgag
    12301 acgcctgaaa caatccagca gcaaaaagaa gcattgaagc aagaagcaag agcagaccag
    12361 cttcgtgcag ccatcgtaga aaaagaacaa aggcaaatca gacgctattt cggtagcaaa
    12421 gagggattcg gtcaagcaat ccatgaattc ttgatgaatt atcttggcaa tgagaatcct
    12481 aataatcaat ctaatgaagg aggttccgag tatgaatgaa cacgatgaag cagaatggac
    12541 aaaaaatgaa gaacaaacag aagatcatga agaaacgaac acttcattgg aagaacaaac
    12601 aagtaatcct ctggatgaca cagaagaaat ccctatgcta gaggaaacaa aaatacacga
    12661 aaaagaaaaa gtaactccga cgaatacgaa tactgcagaa aacacccatg cttacgaaat
    12721 aactgaaaat cccgggtatt tagaaggaaa agagcaagat catcaagata tcgtcagttt
    12781 gattgaaaca gcggaagcag aattagcgga tttacgtatg agaaaagatt tgatcgaatc
    12841 agattttcca caattattag aatcatatga tcgttttata ttgaatgaag aaccaatctc
    12901 cacgatcgga aagacaagcc tgatcgaata cttcacgtat gaattactga aaccgttgaa
    12961 tgatattggt ctggaacggt caaattcagc ttatgacaca tggaaaacaa gacatttttc
    13021 gatcaattat acgttgaatg gacaaaacga attagtcttt tcctttgtat taccgaccat
    13081 cgatcaacga taccaagtgg aatcgatgag tctcctaaac gtatcaccag agacaatgga
    13141 aatcaatgtc caagatgacc gggtgctttc tttgatccga cactggtcag tggatcgagt
    13201 attctctgca gggcagatca cgatattcaa tcacaaattg aatcaattat tagcccatgc
    13261 aagaacactt ggttttaccg ttaatcagac attactagac aatacgaagc cacttcgttt
    13321 gaatcttcag agcgaatttg aattgacgaa tgaagtattg gatgatattt ttatcgtggc
    13381 aatgaaaaat ccatcctacg atatggaaaa gatcaacgaa actacttatc aagtacgatt
    13441 agataaagga cagtctttaa cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat
    13501 ctcatctgga gactacccac gatctgtcat tgatttcttt atcaattacg aattcttggt
    13561 cccattaatg gtgagaaagt cctgattgga taagttggat taccagatgt cattcagata
    13621 attctgttcc aaaggacttg cggcagttat ccagaataat tgtcacaagt cttttctgta
    13681 tgtactaaat ggacgtgaat aacttgctga tgaaggaggg atttcattag gaatgtccac
    13741 aaataaaata gcacagctta gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt
    13801 tcaatttatt ccgaatttcc agccaatgac tgctattttt ttatttatag tactttactt
    13861 aagcttaaaa gatgcgttaa ttgtcatgag tctttctatt gcgatcagca gtttttattt
    13921 tggtgttgga ccatgggtca tcggccaatg gatcagctat actgttgttc tgagtttgtt
    13981 ttcaatcgtc tgcttgagaa aaacagtgca aaggaatcta tggttaaagg gagtctgttt
    14041 ttttctggcg ggcatggttt acggaatagg tatgaccgtt tttgatacgc tgttatatcg
    14101 tttgcctcaa ccttggatct attaccttca aggggtgtcg tttgatttga tgcacagtat
    14161 aggcaatgtt gtgttctttc ttgtttttct gccagtcgtc aaacgttttt acaatcattc
    14221 aggaggaaaa aatgaaaaaa ataatttata gtttgcttgc aatgagtgtc agtatactca
    14281 ttttgacaag ttgcagtaca acctatacac aatcggcttc caaccaaaag gaggaagtaa
    14341 aaacatcgca aaaagcaaca atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag
    14401 aagtgttctt caaaaaaggc gatgatttac tgagtatttt gaaacgaaat tttgaagtca
    14461 aagaagataa cggcttcatc acttcgcttg aagggcactc acaggatgag aaaaatcaac
    14521 tctattggat gtttactgtg gacgggaaaa gtgctactac tggtgccaaa gagatcaaat
    14581 tgaatgatgg acaatcggtc attttcaatt tgtctaaact ataagtttca taaaaaactg
    14641 ttaaagggcg aatattgcca taattcagtg agttcagttg atgaaagaag gaaaataaca
    14701 tggaaaattt taaaaaaagc ggaatgtttt ccgtaattgc tgctctaggg gctaatattc
    14761 tagttgctat cagcaaattt gtcggctatg caatcagtgg cagtgccgcc atgctaaacg
    14821 aaagcatcca cagtatcgtt gattgcagca atcagatttt gctgttattc ggtgataaac
    14881 aagccaataa aggacagagc gagttgcatc aatttggtga aggacgagca aaatactttt
    14941 tcagtacaat cgtcgcaatg atgcttttct tcggcggtgg ggcacttggg gtgatggaag
    15001 cttttgaaaa gttgacgcat ccatcccatg aagtgggtaa tccgatcatt gttatagcaa
    15061 tactgttatt tggtttggta atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca
    15121 aagaattgaa tactgaaaaa ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg
    15181 aaatactgat tatttttacg gaagacttgt gtgctgtaat cggtttggtc ttggctttag
    15241 caggaacaat attgacttat gcaaccggga ttgctgcatt tgatgcgatc agcggattgc
    15301 tgatcggttt cttgctgatg ggagccgcca ttttcctagc aaaagaattt tatagtctga
    15361 tcatcggtga aagcgtgaca gcaagcgatt tatcaaaaat caagttagct tttgaacgtc
    15421 ctgagatcag tcggctgatc gatataaaaa cagttcattt aagtccaacg gagattttag
    15481 ttgcagcaaa agcagatatc gttggtaaca aagagaatga agcttactcg gtcatcaatg
    15541 atattgaaaa aaatatgcgt cagtctcttc ctgacaagaa gatgtatata tacattgaaa
    15601 cagataaata tgacccaaat tattctcgta aataaaacgt ttattcatga attgaagcaa
    15661 aaatgagaaa aatataatct tgtttttaaa taaaacggct acaatttagc gaatttatgt
    15721 tacaatgagt ccgctgttta tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga
    15781 aaagtgcgcc atggcttcaa gctttgcatg cagtgatgcc actttgtata agctatatac
    15841 cagtaggatt agcttgcgga gtattgttgc aaaaagttgg atttgatcct ctcttatcag
    15901 gactgttatc gattctggtc ttttccggtg gcgcgcagtt tttagttgca tctatgctta
    15961 cgacgcaagc atcatttgca acgacattat tgatggtttt ctttttagaa ttacgctata
    16021 cattattagg agcaagtctt gccggtttta tgaaaaaaga aaagcggacg tttttggctg
    16081 tcttttctca atcactgaat gatgaaaact atgcggtgaa ctacttaaag ttttcaactg
    16141 acccttcctg gaataaaaga aaggctttat atgtcaattg gttctcaatg actgcatggg
    16201 ccggtagcaa tatgatcggt aattttttcg gctcggtgat tcgagtagat gctgaccttg
    16261 tccattttgc tttgacggcc atgttcattt tcatgtttat catgcagatg aaaagcgcac
    16321 tactgatctt tacaggttta ttctcaggcg tattaggggt cgtattcatg gtattattcc
    16381 aaaatacttt cggattgatt gcagcaacag tcattgcttc atttgccgga tttatgctgg
    16441 agaaggcatt caaaaaagaa aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg
    16501 agccgctctt caacttcccg gaacaggagg ccaatcacca tgactaaact atatttgcta
    16561 cttttagttg tttgtctgtt catcgtggca tatatcccgc gcttgttccc gatgctttat
    16621 tttactcatc gaaaagtgcc atcctggttc agtgactgga tgaaatatgt accggtggca
    16681 ttatttgcgg cgttagcttt taaagatgtt ttcattactc atgaacatct ggatattgct
    16741 tggaatatca aaatagctgc aatgattcta gtagcaggcg tggcttacaa aacacgttcg
    16801 atggcgttgt cagttttgac aggacttgcg tctgtctttt tgctgtctat gctttaaact
    16861 gttttatttt attaaaaaca gagattgcga cataagttgt tcaaactgat ctatccgaac
    16921 tgcatttgca acagtcaatt ctggatgcaa gtttattcgt agggataaaa aagattagtg
    16981 ttggcttatg atgcaagctc ttttttattt taggaattag agagggattt gtccttctat
    17041 gattttttgc tataataggg aagatgttta ttttatgaaa gaatagttga gggaatttaa
    17101 atgaataaaa aattgatgca aggaacattt tggctaacct ttgctaatct tctatgtaaa
    17161 gttttagggg tagtctattt gattccctgg ctaagtatga tggggaacaa tcaagatggt
    17221 atgcttgcta cgacattgta taatgttggc tatcttcctt atggattgtt cctgatgctt
    17281 ggtacagtcg gatttccaaa tgcgattgca aaaaaagtag ctgtagccac aaaagaagga
    17341 gataacgctg cttgtcggct gatttttaga agtacgatca atatcatgtt tgtcatcggt
    17401 atcgcctctg ctgcactgat gtatttattt gctcctttac tagccggaat cagtccgatt
    17461 gctaacgtta ataatgggat actagctatc agaagtttat gcccatcttt gattgctatc
    17521 ccaattctta gtgcaatgag aggatatttc caaggaaaaa atgatctgcg gccttatgga
    17581 acttctttga ttatcgaaca ggctgtgcga gtgatcgtta tcttggctgg tacttattac
    17641 ttgcgcgtat tgactgacgg aaccatatta gaagctgtat tgatcagtac agtcgcttct
    17701 ttcttcggtg ggttagctgc gattatccat atgtatatcg tcggacgcag aaaagacttc
    17761 ttcgaactta aagatttttt gatttccagc cgttatttcg aaagagaaaa ccgatctgcc
    17821 tctgtctcta tcattcggga aacactaccg tttatttttg tcggctcagt cattactatc
    17881 gttcaaatga tcgaccaagt aacgatgaaa ccactgcttc actttttccg tccagagatc
    17941 gcagatcagc aactggaatt cttattcagc cgtgcttctg tcaatccaaa taaattgaca
    18001 ttgatcctga tctccatggt aggaacagta gctataagca gcttgccaat attaagcacg
    18061 atgaagaaaa aagatcggat acaaatcgaa aaaacagtag gagatagttt ttcgattgcg
    18121 ttattgattc ttcttccttc attgactgga atgtctttat tagctggacc actatacaca
    18181 ttgttttttg gctatgatcc tgaaagtgtc ggatatttcc aaatggcttt gctagcttct
    18241 ttgtttttct ctttattcac gatcctatct acgatgcttc aatctttgaa tcaccatcgt
    18301 tttgcgatcc gattaactgt agaagcaatt atcctgaaag tcatcttcca agtaatcgga
    18361 ttaggattag ttggcggata cgggatgagc ttatcaaatg gcttagcatt cggtattgtc
    18421 tttgttcgcg gctatcactt tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc
    18481 agcaattttt tcttaaaaac tttccgctcc accctgatta tgcttgcagt atgttttgcc
    18541 gttttctttt tgctgaatca gcgattgtca atggaatcaa aaagctatgc aatgatttat
    18601 tgtgtggctg taggaagtat tggcggctta gtatttttat tttctcaatt cggaaaaaat
    18661 gggtttcgaa tgttgaaaaa tgttaaacat catagcagaa gcaaagaata ggttaactaa
    18721 tcgttttttg ctgtcacttg aaaaacggca actcgtatga ttacgcttgt cgtttttcta
    18781 ttttccaatt ttagtttcat atctaatctt acttatgata tagttataag gtctggaaaa
    18841 attctttgaa acgaggaaat taaacacatg aaacttgcag tagttacaga tagttcggca
    18901 tatctgccgg aacgtatcaa gaaccatccc gacttattcg ttattccaat ccctttgatt
    18961 atggatggga aaatttataa cgaaggaatc gatatcgaag cggatgaata ttatggactt
    19021 ttaaaaaaca gtaaagattt tcctactact tcacaacctg tcgtagggga agttttgggt
    19081 ttatatgagg aattgaaaga gaaagggtat gacacgattt taagtatcca tctttcttca
    19141 gggatttctg gctttgtcaa cacattattt gcgatgaaag atgacatcag cggagtaacg
    19201 gtcattcctt atgactctaa gatcactagt atgccgatgg gacacatggt agaagctgcc
    19261 ttagacttaa atgatgaagg tcagtccctt gatgaaatac ttgcacatat cgatcgaatc
    19321 cgagataata cctacgctta tctgattgta gatgatttga acaatttagt acgaggagga
    19381 cgtttgacaa atggtgcagc gctgattggc agcttattaa aaatcaaacc gatcctgaca
    19441 ttttctgaag ggaaaattgt tttattcgaa aaaatccgtt caagtaaaaa agcatttgct
    19501 cgagctgaag aaattattgg tagaagaaat aacgaaatac aaccgccagt caaactttac
    19561 gtgatacatg caaataattt agaagtagcg attgcggaga aagagaaatt gcagaaaaaa
    19621 tatccaaatg cagaaatcga aattggtcat ttcggaccag tcattggtac acatttaggt
    19681 gaaaaagcca tcggcattgc catttcagcg caataattcc ttttattcaa aaaacatacc
    19741 aaaaatattc caacatcatc ttggactttc tacatgttac taatgagcgt gtaaaagaac
    19801 gagatggtgt ttttatttct atcaatgaag ctctttttct ttgcaatcct cacttcaatc
    19861 ctctataatg tcgcatatag tttagtaaat gagtaaacta ctaatttact tatttactaa
    19921 aaataaaagg atgaggagtt aaaataatgg aaataccaac aaatttaaaa cataaaccag
    19981 taatcgttgt agaagactat gataaagttg atggaagaaa tgcattaaat acggatgcaa
    20041 aagggctttc actgggcctt gctcagtgga atgatcgtgg aaaagtcgat atctcaggca
    20101 aggtatggcg acatactgga gaaaaatggt cacgacagtc ggaagaatta ccaatcacac
    20161 gtattttaga tttagcgatc ttagctgcac aaggaagttt atacttccaa gatgcttatc
    20221 gttatgaaaa attttatgat ccagaaaatc cagtcgtaga catcattgga ttacaaggga
    20281 accgaatgac ggtagaagta gataccaaaa atccaaagat cgatgaagac atcattttgt
    20341 attacgatac actacaaaaa gacggagaac tgattgggga acgattccgt attttaaaac
    20401 gtcttttaga tgagctagga tattaataga cagagatgat caaaagggga agagaagcat
    20461 ggagaatttc tcactaacag aaaaccgaac cttttcacgg ctagaaaagc aaatgatctg
    20521 gaagaaaccg aaaagccatc ggacaagtgc agaagaatgg cggatcgcct ccgaaatcaa
    20581 agggaattgg caagatcctg aaatgaaaat cagtaacgta cttttggaag gagatgccgg
    20641 gtcggggaag acacaattag ccaaagcact atctgctgat ctgcaacttc cctatacaaa
    20701 agtgacctgt tttgcagata tggacaaatc agatgttttc ggagccttat tacctgtagt
    20761 agattctaat aaggaacaag accaagaatt actagaagct atttaccaaa cagatacact
    20821 tgaagctgta ctgacactga tccagaacca ttacggcatt gatccttttt ctgctaaaga
    20881 aaaattagca gagctagttc aaaggatcga agctgattat ccagatgcaa tccattacag
    20941 ctattaccct tctgaaatcg ttcgagcgat tgaaaaagga tatttattag agattcaaga
    21001 gccgactgtc atccgagatg cctctgttct tgtggcactt aactcagcgc tcgaaccaaa
    21061 tgggatgttg aatttaccga caggaatcat tcgtcgccat ccagattgcg tcattgtgat
    21121 cactacaaat cgaaattacc aaggaaatcg cccattaaat gaatctttaa gagatcggat
    21181 gcaacatgcg gaaaaaatgg atcttcctgc cttagaagtc atggcagaac gtgcgatggc
    21241 gaaaactatg atccaaaaac aagaacttct cttaaagatg gcagagatta tccgtttgtt
    21301 ggatgaaact gcaaaagcta acgccatcaa aggtgtagca ggaatgcgtt cttattttta
    21361 ttgggcaaat acctataagc aaggacaaga tttactccag tcgatttatc caaaagtttt
    21421 gtataaatta tccactgatt cagatgaatt ggcaattctt gaacaagctt tgtctgacag
    21481 tggattgcta ctggaacttc aggacatatt gagaaaagaa aaatggggtc atcctcaatc
    21541 tgagcataca aaaggaagaa ccattagcgc cgaagaagca aatgaacgaa acatcactga
    21601 aaatgctgaa gaaattctgc gcttagatga aaagaaatcg ttgtctgctg aagaaccaaa
    21661 tgagggagaa gagaaacaag aagaaacaat agaaaaaaac gagattcctc ctcaaatgca
    21721 aaaagaacgc agtagcgata tcgaaggaaa aaatcaaaaa gaacaacaaa caggagatga
    21781 ttctcaagaa atgtctgctt ctgacatgga agcacatgat aaggaaatca agaagcaact
    21841 gaataaagaa gcgcgacaaa tcatgaagga aacgattcat gaaaaagaag gtctcatcgt
    21901 tcaccgacca gctttccaag gaaaaacgcc ggaagcacgt gagctacaca tgcaagtaat
    21961 gccaatagta gaatcactta gccggcaaat tttagagtta ctggataatg aacaaacaga
    22021 gacgtaccaa aaaggaaaat acgaaggtca gcggttcaat gcaagcaaag tagcatatgg
    22081 tgatttgaga aattttgaca aaaagaaccc gccacatgag caaccttctt tagcggtagc
    22141 tgtacggatc gatgaatctg ggtcaatgat acgggatgat cggatcgaag cggcaaaaaa
    22201 agcagcgatt gccattgccg aattttctaa gaaagtcgat atcccattgt tgatttacgg
    22261 agatacagca gaccgttcgt caagagaaaa gacttctttg ttttcttata aagaatttga
    22321 agacggattt caatggttaa atgaaaaatt agtcactatg aaaccaaggc aaaacaatcg
    22381 tgatggtgct gcacttcgtt tagcagcaga aaaattaaac agacaatccg caacaaccaa
    22441 actgttgctt aatattagtg acggtcagcc aaaagcgttg ccggattata caggcaaaaa
    22501 agcaaaagaa gatatccagt ctgttttgaa agaatatgaa cgtcaaggaa tcctatttgt
    22561 ctccgcagct attggccaag acaaagaaga aatcaagtcg atctacggtg aaagtcgttt
    22621 tgtagatatt actgacttga atgaatttcc caagcaaatg attcaactga ttgcccgcta
    22681 tctatgataa aataaagctc aacgaacgca cttagcagat tcgttgagct tttcgtttct
    22741 agttaccggt aacaaggata cttctaaaat agaatcggtt ataatcaaga gggaccgtta
    22801 aaggagtgaa acgatatgat acaagaacaa aaatggtgga aagaagcagt aggctatcaa
    22861 atctatcctg ctagtttcaa agatagcaat ggcgatggtc aaggagacat caatgggatc
    22921 cgtgaaaaac ttaattattt gaaagatctt ggtatcggct ttatctggat caatccgatc
    22981 tatcaatctc catttgtcga taatggttat gacgtaagtg actatcaaga tatagaagag
    23041 agattcggaa cgatggaaga ttttgattta ttgctaaaag aagcacatga attagggatc
    23101 aaagtgatta tggatcttgt catcaaccat agttcggatc agcatcaatg gtttgaagaa
    23161 tcgaaaaaat ctaaagaaag cccgtatcgc gattattaca tttgggtcga cggggtagat
    23221 ggcaaagaac cgaataattg gacatcgatt ttcggcggtt ctgcttggga gtattctcat
    23281 gaaactggac agtattatct gcatgttttt gcaaaagaac aaccagactt aaattgggaa
    23341 agcgagaaat tgaaagaaga actattcaat atgatccgat ggtggttgga taaagggata
    23401 gatggatttc gtttagatgc gatttctcat gtaaaaaaag atgaatattc agtaaaagcc
    23461 acagagaacc ctttctcacc ctttcaaaat gtctcaggaa tcgaagaaca tttgaccgat
    23521 ttgaaacatg tttttgaaga gtacgatatc atgactgtcg gagaagcaag tggtgtcact
    23581 gcagaagaag gaccacaatg ggtagggaaa gacggttatt tcgatatgat attcgaattt
    23641 gatcatatcc atatctggca gcaagaaaaa gaagggcaat tagatgtcct taaattgaaa
    23701 cttgcattaa gcgcttggca aacttcattg gatggtatcg gatggaacgc tttatatatg
    23761 gaaaaccatg atgttcctcg tgccgtttca gtgtttggag atactcgtcc cgatttttgg
    23821 gctatgtctg caaaagcaat cgctatgatg tatttctttt tgcaaggtac gccatttatt
    23881 tatcaaggac aggaaatcgg aatgacgaat atgccctttg aatcgatcga tcaagttgat
    23941 gcagtagatt cgaaaagact ttataaaagg ctgcttgcgg aaggtaagac aagagaagaa
    24001 gcattggata tcattcgtga aacaacgaga gacaacagca ggacacccat gcaatggact
    24061 tcggaacaat atgctggttt ttctacacat gaaccttggc tgatcactaa tccaaatacc
    24121 aaaacgatca atgtagaaca acaagaatat gaaccagagt cggtcctgca attctataag
    24181 aacatgatcc gcattagaca aaccaataaa ggtctgatat acggttctta taaagaatat
    24241 cttcatgaac atccacaact ttatgtctat gaaagatatt tagaagatga acaatatctt
    24301 attatggtaa acttaacaga atcacttgct gactatgaac ttccaaaaga agcagatcag
    24361 tcctggacat tactcttgtc aaattcctct agcggagaat ttgaagctaa aggcatacta
    24421 gcaccttatg aagctcggtt atataaaaca aacaagtaaa acttcctcgt taaagttcat
    24481 tagttggact ttgcgaggaa gtttttcaga ttgctctgtc aattactcat ttcaataatt
    24541 cgctctagga ccaccgatat atttaggacg agagcgaagg gctgtcacgt gagcttgtcc
    24601 aagggttttc aaacgaggtc tgacaggtac ttggacatgt ttgatatgca taccgattga
    24661 tgtgtcaccg atatcgatac cggcttgtcc aactacgtgt tccacttcga caggatcatt
    24721 gaactggtca aaagcagcaa cagaacaagc acctccagca tgtagtgcag gaacaacaga
    24781 gacaatttcg aaattttttg cttctgccac tgttcgttct actactaatg ctcggttcaa
    24841 atgttcacaa ccttggacag ctagcgcaat ttctttagga tccaacaact cttttaacgt
    24901 acggatgatc cattgaccaa cttccgcact ggaatttttt ccaatatgtc ctccaacgac
    24961 ttcgcttgtg ctgcatccta aaacaaaaag atcacctttt ttcaagtgtg cctcagccaa
    25021 tatgtcatta actatttcag tcaattggtc ttttaattct ttttctgaca acttcatttt
    25081 ctaaaacctt ctttttcaat taatattgct tccgtgcttg aatacgttga agacttgcag
    25141 ttataggaaa ggcaagtccc attccaatca gattttggaa gatgtttcct ggtatagaag
    25201 ccactccagc cggccaatca tataaaatcc aaccggcgat accatagccg atgatcataa
    25261 ctaagcttcc taataaaagc cctaatcccc acatacgagt agaagatttg ctgaaagaac
    25321 cagcaacata tccttgtaac ccgtggatca ctaatgaaaa aactgcccac tgcggatatc
    25381 ctgaaatcaa atcgatcaat agaccactgg aagcaccaac aactaatcca cccgttggac
    25441 cataaagaaa agcagcggta tagatcccgg cctcgcataa tgtcacaaat ccattcgtag
    25501 ccggtacagg gatcaaaatt gttaatgaaa gggcaactgt caacgcaatc agcatagcat
    25561 agatcgttaa ttgcttagtt ttcatttctc attcctcctt tttgaatacc gccagaccag
    25621 acacttccgg tatgatcgtt catcagcacg ccattagaaa tacaatgggc aacaaatttt
    25681 ttactttctg ctactgcttt ggtaaaatct gcccctaaca caagattcgc tgttattgca
    25741 gaagaaaagg cacaaccggc cccgtttact gttgtagtgt cgattttttt atgagaaaat
    25801 acctcataat gatcaattga atagagaaga tccacagctt catctccagc catccttgtg
    25861 ccgcctttga tcacaatgtt ttttgttcct gaagcagtga gttctttagc gagatggatc
    25921 atttctgtta acgaagaggg aagagcttga ccagaaagta aagcagcttc tgccaaatta
    25981 ggcgtaatca tcgtaacaag tggaaaaagt tcttcgatga gctgcgaaat atacaattga
    26041 ttgatcacag cttcagtttc tttgaatgcc aaaacagggt ctaaaatgat tgggatattt
    26101 tgttttgttt ttatgaagtc tcgaacaacc atgattgctt cacttgaatt caataaccca
    26161 attttgatac catctaatga agtcatttta tcaatcgaaa ctaactgtcg tttaagcaat
    26221 tccaaagata tagattccag cataaatcgc tcattaatat ctagtgcccc tatagaagtc
    26281 aaggcgctta gtccgaatag accaaaattc tcaaaagttt ttaaatctgt ttggattcct
    26341 ccaccagcaa atggatcaga accgccaatt gtcaagattc ttttcataac attttcctcc
    26401 atgaataaga gtataacgaa attttcaaaa aagaaaaaca gccaattggc atatttttat
    26461 ctcatccaat ttaaaaaaac aaaaagaaaa gaaagaccaa aatggatctt tctttcctta
    26521 aatagttagg acttttgtga ttttaattct ttctcgattt gaagccgttg cactttcatt
    26581 gtagctgttc gcgggattgc atcaaaatca cggatgatag ggacgttcaa gcgaggaagt
    26641 tcatggactt gctcccacca tcgattccaa tccatttctt tatcaggagc taaagcaata
    26701 atcggttgtg gagaatgatt tttatccctt acaatcacta cttctgccaa aaaatctaac
    26761 gaatctaata aaaagtcttc aatagctaat gtactattga tcgtttcgat caaatccact
    26821 tgccgatctt tcaaaaatag gtggccatgc ttatccataa aaccgtaatc tccgctatcc
    26881 caccaatcgc cataaacatt ttcctggaac cgtgcatctt ccttgtaata agtcaaagcc
    26941 cgtcctttag acagtaattg tatatgacca tctgtgtttt caggtaggac attcccaact
    27001 gaatctgtaa tccgagcgct tgtcatgtct tccagtccaa cgcccatatc tcttgcatca
    27061 cttgttttca aactctctag tgtatgagcc ttaagaatca ttggtccgca ttcactttgg
    27121 ccatatactt gaagaaatac cgcatcctgt gccatcgacg ttcgcaaaaa tgtcttcatt
    27181 gtctggttgt ttatagcatc aaaagtggag tgatagtatc ggatacccga aaaagcttct
    27241 ggatgctcct tagcagtaaa acgccactga acaaagttat tcggatgggt ctctagtgca
    27301 attggccggt gagcttccaa catatgaaca acttttgaac tttgtgcgtt tgctaaaggc
    27361 atcataggaa atcccatgga catcaaagaa gagataccaa tattgaatct ggaatgcact
    27421 ggagagatgt gaaaagcgat taatttcttt tccgaaattt ttgtgaaaac tgttttttgc
    27481 catttcgtcc gccatcccat agaatgagca gaatgacaaa taagtttagg gataccagtt
    27541 gtaccagaag tatgggtcat ataagaaatt tcatttttgt ctaaaaatga ttgagaaaca
    27601 gacaaagcag gttgttccat taaataaaga ataggaa
//
LOCUS       DASHWW010000030        26146 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.030, whole genome shotgun sequence.
ACCESSION   DASHWW010000030 DASHWW010000000
VERSION     DASHWW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.030"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            126..3653
                     /locus_tag="U2R64_001504"
     CDS             126..3653
                     /locus_tag="U2R64_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HEM8918327.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3650..7372
                     /gene="addA"
                     /locus_tag="U2R64_001505"
     CDS             3650..7372
                     /gene="addA"
                     /locus_tag="U2R64_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEM8918328.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7441..7782
                     /locus_tag="U2R64_001506"
     CDS             7441..7782
                     /locus_tag="U2R64_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918329.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8091..9134
                     /gene="pheS"
                     /locus_tag="U2R64_001507"
     CDS             8091..9134
                     /gene="pheS"
                     /locus_tag="U2R64_001507"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEM8918330.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9139..11559
                     /locus_tag="U2R64_001508"
     CDS             9139..11559
                     /locus_tag="U2R64_001508"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEM8918331.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11729..12739)
                     /gene="trpS"
                     /locus_tag="U2R64_001509"
     CDS             complement(11729..12739)
                     /gene="trpS"
                     /locus_tag="U2R64_001509"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEM8918332.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12993..13730
                     /locus_tag="U2R64_001510"
     CDS             12993..13730
                     /locus_tag="U2R64_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8918333.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13744..14559
                     /locus_tag="U2R64_001511"
     CDS             13744..14559
                     /locus_tag="U2R64_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEM8918334.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14572..15219
                     /locus_tag="U2R64_001512"
     CDS             14572..15219
                     /locus_tag="U2R64_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8918335.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15235..15891
                     /locus_tag="U2R64_001513"
     CDS             15235..15891
                     /locus_tag="U2R64_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8918336.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16053..16874
                     /gene="racE"
                     /locus_tag="U2R64_001514"
     CDS             16053..16874
                     /gene="racE"
                     /locus_tag="U2R64_001514"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEM8918337.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16877..18232
                     /gene="rph"
                     /locus_tag="U2R64_001515"
     CDS             16877..18232
                     /gene="rph"
                     /locus_tag="U2R64_001515"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HEM8918338.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18233..18751
                     /locus_tag="U2R64_001516"
     CDS             18233..18751
                     /locus_tag="U2R64_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEM8918339.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18858..19358
                     /locus_tag="U2R64_001517"
     CDS             18858..19358
                     /locus_tag="U2R64_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8918340.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19638..20558)
                     /locus_tag="U2R64_001518"
     CDS             complement(19638..20558)
                     /locus_tag="U2R64_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEM8918341.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20723..21736
                     /locus_tag="U2R64_001519"
     CDS             20723..21736
                     /locus_tag="U2R64_001519"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEM8918342.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21846..22601)
                     /gene="fabI"
                     /locus_tag="U2R64_001520"
     CDS             complement(21846..22601)
                     /gene="fabI"
                     /locus_tag="U2R64_001520"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HEM8918343.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22821..23261
                     /gene="fabZ"
                     /locus_tag="U2R64_001521"
     CDS             22821..23261
                     /gene="fabZ"
                     /locus_tag="U2R64_001521"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEM8918344.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23376..24137)
                     /locus_tag="U2R64_001522"
     CDS             complement(23376..24137)
                     /locus_tag="U2R64_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8918345.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24326..25420
                     /locus_tag="U2R64_001523"
     CDS             24326..25420
                     /locus_tag="U2R64_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEM8918346.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25506..>26146)
                     /locus_tag="U2R64_001524"
     CDS             complement(25506..>26146)
                     /locus_tag="U2R64_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HEM8918347.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNG
                     LPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8643 a         4530 c         5507 g         7466 t
ORIGIN      
        1 gtatacttaa aaaagtagaa atatcagaac cttaaaagga tataatttga agaatataga
       61 acaaatgttc agtatttttt gatataataa aggagcaccg tatcatgtgt tgaaggagga
      121 aaagcatgtc tttacaattt attcttggaa acgggaaaaa agatcaccgt caagtcttga
      181 tcgacgaagc atccgcttgg ctcgaccagg atgcaagtaa ccaagtattt ttccttgttc
      241 ccaactacag caaattcgaa caggaacaag aaattttagc ggagatgcga agaagaagcg
      301 gaaaaaaaac tttcagcaca acaaacgttc aagtatttag tttttatcgt ctggcttggt
      361 atttgctgca acagacaact cttcttacag gaaatgaatt atcagaatca ggatctgcaa
      421 tgatcttgcg acagatttta gaaaaaaatg aggaagaatt aacaatcttt cgcggagaaa
      481 tcaataaaag agggtttatt cgtcaattac aagaactcta cagtgaattg cgtacaggaa
      541 atattcaacc agaagacctg atgcttttat ttggtgattc acctaatgca gaagaccagc
      601 aacttaaaat gaaagacttg aagctgattt tttcagctta tgacagcgaa ttgactcaac
      661 gtgcactaac aaatgaagat gcactatcta tactagcaaa ttatatgcag acacaagatt
      721 tcaacaacgt caaatttatt gtcagtggtt tttctcgaat caatggtcaa gagtatcaat
      781 tactgcaggc aatgatggaa aaggggcaat tggttgtcga tttattgctg gatcgtcctt
      841 atacagcgga tcttccagaa gtacttacgc tctttcatga gactggaaag ctttatttcc
      901 gtctttttca aagtgcaaga gaacggaaag tccctatatt agtggaccga tttgcaccag
      961 agcagactcg tccgacagag cttcaactgc tgcaaacaat gtgggaagag acatctagcc
     1021 aaaagaaagc ggcagtacac aaaatagggg gacaagagca tctccatttg tgggaagctg
     1081 aaaatccaac tgaagaagtc cgacaattag ctgttgaaat cagacgacta gtcagtgaag
     1141 aaaactaccg ttatcgtgat atccaagtgc tgacaaaaaa tatgtcttta tatggaaata
     1201 tccttcggcc gatctttcaa gaaatggcaa ttccttttta tatcgatgaa gaacaaatga
     1261 tggaaaatca tccgctgatc gaatggatca acagtctgtt cgctcttgac cgctattctt
     1321 atcggctaag tgatattatg cgttttttca aaactgaatt atttctgtcg acggaagcag
     1381 aaaccgaact tgatgaatgg aaacaagagc gagatgaatt caggaaaaaa ctggacatca
     1441 ctgaaaatgt agcacttgct tacaattatc aaggaactta ttggactcgt gaaaaagact
     1501 ggcagtttgt ggcgtatgat tttgaagcag aacagattga agacgtacag tatttggaag
     1561 aacagtcaaa tacgattaga cgattatttc agaaagctgt accagtattt ttgaaaaaaa
     1621 taaagaaaag caaaacagga caagaggccg caaatgtttt ttatcaattt ttgatccaaa
     1681 gtggcgtaca gcaacaatta ttgttttggc gtaatcagga agtagacaga ggaaacttag
     1741 aagcggcaag aaaccatgag cagacatggg gagcgctgat tgatctgttg gatgaatatg
     1801 tagtaattta tggtgaatcg gcttttgact ggtcactgtt ccaagaaatc attacaagtg
     1861 gtctagaaaa tctaagttat ggtaaaatcc ctaccgcaat cgaccaagtg cgaatcaatc
     1921 gtttggaatt agttcgacca aatcaagctg ccgtcacttt tgcattaggg ttgaatgatc
     1981 aagtgtttcc agaccgaaaa gagacaaaag gattgttgtc cagtgaagaa cgagaagtat
     2041 taaatcaggc cttgccagat ggacagtttt tattcgaccc atcaaaggaa agtatctctt
     2101 ttgagccttt ccaagcctat cttgtttttc tttccggaac agatcgatta tatcttagtt
     2161 atgcacaaag ctatgacaca gatggttcgc tgaagatgtc tccttatttg cgtagaatca
     2221 cagaatattt atctgttccc gtcgagagaa aagagcattt gacgatcgaa agcgacccta
     2281 attgttatgt agggacttac agaagcggaa tcaatacagt caataggatt tatcgattag
     2341 ctttagatga aaaaaaacct gtaccaaagc actggcaaaa gctcaaagaa ttagtactga
     2401 attcgtcatg gcgaaatttt gctttacaga tttttgaaag tcaggaacat ttaaatgttc
     2461 ctgtttcgat gccagaaaaa atggcggaag agctttatgg aaaagagatt tatacttcaa
     2521 tttcacgtat ggagaatttt tataattgtg aatacaaata cttcatgcaa tttggtttga
     2581 aattgaaaga acgaactgtt tatggtctaa ctccagcagc aactggtgat ttttatcatg
     2641 aatcattgga tcgtttcttc aagctactgt tttcaaacca attatcctta gtgaatatgt
     2701 ccgatgcgca gcgtagagac tttactgaaa aagtgctgca ggaagtattc ggagaacttc
     2761 ggtttgagat attggatagt tctgcaagaa tgaactatat ccgctaccag ttaggacaga
     2821 cgattcaaaa agtgacatgg gctttgcaaa aacagagcaa aaatacaggc atgcatcctc
     2881 ttcagacaga gattctattt ggtcagattg ctggagcaaa aggtatcaca ggtctggaat
     2941 taccgttgag taatggtgga aaactccatg ttcgagggaa aatcgatcga atcgatgtag
     3001 cttctgaaca agaagatact tggctaagcg tcgttgatta caaatctagc ggacgttcat
     3061 tcgatgtcac agaagcttat tatggcatgg ctatgcaatt attgacgtat ctggacgtag
     3121 cattgatgga tgcggtacgt ttgactggaa aggcggctgt taaaccagca ggatcatatt
     3181 atttacatgt tcataatcct gtattgacgg agacagatga tgtagagaag aatacattga
     3241 aaaaatttag ttatgatggc gtttttgtcg atgatcccgc tcttttagaa gtactagatc
     3301 attcactgga agcaaaagaa caatcactga tctatccagt gaaaaaaaat gcgaaagatg
     3361 aataccaaaa aggtagtttc agtaaagaca aatttttcac ggaagaagaa ctgcaactat
     3421 tcatggcgca taatcgggaa aatatgcggt tagctggaga tgcgattact tccggagaaa
     3481 tcaaactaaa tccagcttat aaagataaac agcggattgc ctgcgaattt tgtccattca
     3541 gaagcatctg tacgtttgat gtgatgctga aagaaaataa ttaccaccgt ctggagaaaa
     3601 tagataagga agaagcactg cgtagaatat tgaaaaggag tgaagaagag tgaatcaaat
     3661 tcctttaaaa ccgcaaaatg aacgattcac agatgatcag tggcaagcga tttttgatca
     3721 aggagataat ctattagtct ctgcgtctgc cggatcaggt aaaactacag tgcttgttcg
     3781 aagagtgatt gaaaaactaa aaatgggttt tgatatcgat gaattattga ttgtgacatt
     3841 tactgaagct gccgcaagag aaatgaaaga aagaattcaa gaggcattac aagaatccgt
     3901 caatagcgaa agtgaccctg tacgtagaca gcattttact aagcagttag ttttattgcc
     3961 cacagcgaat atctcaacct tacatgcttt ttgcctgaca gttattcgac gttattatta
     4021 cttaattgat attgatccag tctttcgcat gttaacagat gaaacagaaa cgatcttgat
     4081 gaaggaggat gtgtgggacg agctgagaga agcactttat gcagaaaatg atgaacgatt
     4141 tttccaatta acaatgaatt tttctaatga tcgttcagat gacggcttga cgaatctggt
     4201 gttttctctt tatgagtttg cccgtgccaa ccctgacccc caaaaatggc tagaacagtt
     4261 aagcgataat tatcgtttgc ctgaggggct agcgaaatct cgattatatc aaaaacaaat
     4321 ccgtccttta gttttggcag atatatacca atgtgtacag ttatatgaac agatgactca
     4381 gttagcacaa ggtgaaggat tagaaaaaat gcatgagcaa gtagctggag aacaacagca
     4441 gatcaagaat atctatgaag cgttctcgca agatcggtta gaagaagctt atgctggttt
     4501 ggaacaacta actttttcaa cttttaagag cagtcggaaa gcagaattga aagaaatttc
     4561 caatgaagtc aagggcatga gggataaagc aaaaaaactg attcagcaga taagtaaaag
     4621 ttattttcct gtttccccaa gccaaatgga agaattaacg gacaaagcac taccgttagt
     4681 cgaagaaatg acaaaagtca cgcaaagctt catggacggt ttcagtatgc gtaaacggga
     4741 aaaaggtgtg ctggatttca atgatctgga acatttagcg ttgcagattc tcacagaaaa
     4801 aacgaaagat gtatggctgc caagtgaagc ttcaaaacat tatcgaaaaa aattcaaaga
     4861 agtaatggta gatgaatatc aagacgtgaa ccaattacaa gaagccattt tatactggct
     4921 aagagaaccc gatgatacaa aaggaaatat gttcatggtt ggggatgtca aacaatccat
     4981 ctattctttc cgtttagcag atcctagttt atttatcggg aaatacgaga atttctcaaa
     5041 gaaagaaggc ggacgtcgaa tcgttttggc tgagaacttc cgctctagaa aagaagtcct
     5101 ttcttttacg aatcttattt ttgaacaact aatggatcca gcagtgggtc aaatcaatta
     5161 tgacgaagca gccaaactga tccaaggatt ttcagacttt ccagagaatg aacagtttga
     5221 gccggaaatc atgatctatg aaaaagaaca ggaagaatca gagattgaga ttccgacgga
     5281 tgatatactg gaagacaaaa cagaaggcga actttttatg acaggactaa aaattcgtca
     5341 attaattgat tcctccttta tgatttatga taaaaaatca aaaaaaagtc gtccgataga
     5401 gtacaaagac attgttctct tgacacctac aaagaagaac aacttaacga ttttagagat
     5461 tttcaaaaca ttggatattc cattagagat gaatgatgct caaaactatt ttcaagcgac
     5521 agaaattcgc acgatgatct cgctgctaca attaatcgat aatccctatc aagatattcc
     5581 gcttgcggct gtattgcgct caccgatcgt gggtctgatt gaaccagaat tagccagcat
     5641 tcgattagct aaccgtgcac atacttacta tgatgctgtg cttgcttatc aagcatcaaa
     5701 cgaagatgaa ttagcagcta agctggaaca ttttggcaag caactagagc attggcgaga
     5761 acttgctcgc cgttcttcga tcactgactt gttatgggat atctattatg agacgggata
     5821 tctagagtat gtggtcggtc tgccagcagg ggcacagaga caagccaatc tttatgcatt
     5881 ggttgatcgt gccaaagctt acgagcaaag ttctttcaga ggattatacc agttcgtgcg
     5941 tttcattgaa aaaatgcaag aaaaagataa agacttagca gaaccagtca tttcaataga
     6001 agataatgct gttcgcgtta tgacgatcca tgcaagtaaa ggcttggaat tcccagttgt
     6061 atttttgtta gatatgacaa aggagttcaa cttacaagac ttgcgcaatc ggtatgcttt
     6121 tgaagaaaaa cttggagcag gaattcgcta tatggatcct gaaacacgag tgttatatga
     6181 tacgttaccg tttcaagcca tcaaattggc aaagcaaaac aaattgttgt cggaagaaat
     6241 gcgtaaattg tatgtaggat tgactcgggc agaacaaaag cttttcattg tcggttccta
     6301 taaaaataaa gagcaaatga tccaaacgtg gtctgaagca gctgatcatg aggagttagt
     6361 ttttgatcct gcgctacgtt tgaagggcag aagcagcttg atgaattgga ttggttacgg
     6421 attgatccgt catcctgaaa tgcagaaata cttagaggaa gaaatttcga cttctcttct
     6481 tcaacattca aatgcacagt tttctatttc atggatgaat cagcaatcga tcattgaaca
     6541 aagacagttg cttgctgaaa aagaactggt taacttagat cagcagatga aagaagatga
     6601 aactttatta gcagattcgt tacaaaaacg tctggcatat gaatatcctt atcaagcttc
     6661 ttcacaaacc acaagttatc aatctgtatc tgaaatcaaa cgattattcg aagatccaga
     6721 tgatacacaa gaatcacgtt tgactctgga aagcagtcag aacaaagcag catcccgtca
     6781 atttcgttat acgcaagaac aactagcaga accaaaattt ttgcaaaaag atcggcaagt
     6841 gtcagcagct gctgttggaa ctgctacgca tgctttgtta caattactgc cattagagat
     6901 gccaactaca gagagtatcc atcaaaaatt acaggaattg gtaaggaaac ggttagtaga
     6961 cgaaaaagtc gcgaaaaaag tagatgtttc ttctattata tggttctttc aaacagaact
     7021 tggtcaacag ctgattgcca acaaagaaaa cgtaaaacga gaacaacctt tttccatgct
     7081 gcttcctgct gacgaagtat ttcaagacta tccaaatcaa gaagatgaac tattaatcca
     7141 cggaatcgtc gatggatacc tagaagaaaa agatcatctc aatatctatg attttaaaac
     7201 agattttatt ttacatccgg atgatccagc agaaatagat gcaatcgtcc aaaaatatca
     7261 aggacagcta agactttacc aacaagcaat gtcagaagct ttgaataagc cagtagaaaa
     7321 tgttttccta attttgcttc gagtgaaaca aattataaac attaacaaat aattataatt
     7381 gagcaaactt gacttatgtt ttgtaaggat tatgctatac tctgggaaga ggtgagtatg
     7441 atggagctaa cacagacaga attcgtttta tgccctaaat ttgaaaaaac attctctatt
     7501 ttaggaaaaa aatggaacgg attgattatc gatgtactac tcgaaaacgg tccgcaacgc
     7561 tttgttgagc ttgcggcaaa aatcccgatg gtcagtgatc gagtattagt cgaacgcttg
     7621 aaggaattag aaaaagaagg aatagtcact cgaaactttg cctgtagcga aaagagccgt
     7681 tcagaatatc tcttgactga aaaaggagca gacttgcaaa aagcgatgcg tcaaatacaa
     7741 gtttggagcg aaaaatggat cacagaggaa gaatgcggtt gattttgtaa aaaaaatctt
     7801 gtaaactata gtccatacga ataagtaaag aacgatgacg aaaaagagta gtttggctaa
     7861 accagttcag ggagatctgt cgcagactga aagcagatcc tgtgtttgaa aaatgaagtt
     7921 cactttccga gttcgtctga taaaatcaga ccggcaattg tcgttaacga agtaagagtg
     7981 cggtgtaagt catttatccg caaattagga tggtaacgcg aagacctcgt tccttaacag
     8041 gaatgaggtc tttttgtttt gtatttggaa tttaaaggag gaacaagcac atgtctctac
     8101 aagcacaatt agagagcttg aaagaagcaa cgctcgtcaa aatcacagcg gcacaagatt
     8161 taaatgaatt aaatcaaata cgtgttgaaa cgttaggaaa aaaaggaccg atcacagaag
     8221 tattacgtgg gatgaaagat ctaagtccag aagagcgacc aaaagtcgga agtttcgcaa
     8281 atgagatccg agatcttttg acagaagaga tcgagcgaaa aaaacaagta ttagaagaag
     8341 aagcgttaaa tgcagctttg gcaaaagaaa caatagacgt gacactacct ggtagaaaag
     8401 taaaacatgg tacacgtcat atcgtgacac aaatcatgga agaaattgaa gatatttttg
     8461 tgggtatggg ctatcagatc gtagaaggat atgaagtaga atctgatcat tacaatttcg
     8521 aacggatgaa tctgccaaaa gatcatccag caagggacat gcaagatact ttctatattt
     8581 cagacgagat attgattcgg acacatactt caccagtcca agcacggaca atggaaaaac
     8641 atgatttctc taagggtgct ctacgaatga tctcgccagg gaaagtcttc cgcagagata
     8701 cagatgatgc gacccacagt catcagttcc atcaaattga agggctagtt gttgataaaa
     8761 acatcacaat gggcgacctt aaaggaacat tagaagtcgt aatgaaaaaa atgtttgggg
     8821 aagatcgtga aattcgtttg cgtccaagtt atttcccatt tacggaacca tcagtagaag
     8881 tagatgtcag ctgtttcaaa tgtggtggtg ccggttgtaa cgtatgtaaa tacactggat
     8941 ggatcgaaat tttaggagct ggcatggtac acccgaatgt gttgaagatg tcaggaatcg
     9001 atccagaaga atattcaggc tttgctttcg gccttggacc agaccgcgta gctatgttgc
     9061 ggtatggagt gaatgatatc cgtaatttct atcaaaatga cttacgtttc ttaagtcagt
     9121 tcaaggggga gtaagaaaat gttagtttca tataaatggc tcaatcgtta tgtagattta
     9181 tcgaatgtaa caccaaaaga attagcggat aagatgtctg tgacaggaat cgaagtagag
     9241 ggagtaacgg ttccagaaga aggcttgaaa aaaatcgttg tcggtgaagt caaggaatgc
     9301 gtaccacatc cagattctga tcacctttct atttgtcaag tcgatattgg cgaagacgaa
     9361 ctgtctcaaa tcgtttgtgg agcgcctaat gtgaaggttg gaatcaaagt gattgttgca
     9421 cttcctaact cacgtatcgc tggtaatgta aaaatcaaaa aaggaaaaat gcgtggccaa
     9481 gtatcaaatg gcatgatttg ctcattacaa gaaattggct attcagatag tgttataccg
     9541 aaagaatacg ctgaaggtat ctattatatg ccacaagaag ctgtaaatgg cgatccagtt
     9601 tttccttatt tggatatgga tgattcgatt attgaattat ctatcacacc gaatcgtgcg
     9661 gatgcattgt caatgcgtgg cgtagcttat gaagttgggg caatttatcg tcagactcct
     9721 acattcgatg acgaaaagct ggtagaatcc tcacgtcctg ctagcgataa aattcaagtg
     9781 gaagttgaag ataaagaagc agttcctgct tatcaaatca gaatcattga aggagtaaga
     9841 atccagccaa gtcctcaatg gctgcaaaat cttttgatga acgaaggcat tcgtccaatc
     9901 aacaatgtag tagatgtgac gaactatatt ttgcttttat tcggacaacc actacatgca
     9961 tttgactacg acaaattgaa atcaaaagag atctttgtcc gccgtgcaaa agaaaatgaa
    10021 acattagtaa cactagatgg agaatctcgg gaattgacaa ctgacaatct cgtcattact
    10081 aacggcaaag aaccagttgc tttagctggt gtcatgggag ggttagactc agagatcacg
    10141 aatgaaacaa caacagttgc actagaatct gctttatttg atccaatttc gattcgtcgt
    10201 acagcaaaac aatttaattt gcgtagtgaa tcctctgcac gttttgaaaa aggaatcaac
    10261 catgcgactg ttggagaagc cagtgaggtt gctgcagcaa tgatcgtttc tcttgcgggt
    10321 ggggaagttc tacaaggcgc ggtcaaaggc tcagagatca aagcagaaga cgtatcagtg
    10381 aagatttcac ttgaacgcat caatcaatat ttaggaacat ctcttgtcgt taaagaagta
    10441 aatgagattt ttgaagcact tggatttagc tatgaagaaa aggagtatgt ttattccgta
    10501 gtagtaccac caagacgctg ggatatccaa atcgaagcag atattatcga agaagttgct
    10561 cgtatttatg gatacgacca gttgccatct acacttccaa gtggagaaac ggttgctgga
    10621 agcttgtcaa aagaacaaga aactactcgt aaaattcgta caatctttga aggaagcgga
    10681 ttgagcgaag caatcagtta tgcattgaca acagaagaaa aatcaagaca gtttgttata
    10741 aatgaaagta atattacacg tttggactgg ccaatgagcg aagaacgttc tgtattacga
    10801 atgaatttga tcagcggact attagatgat atcagttata acactgcccg aaaaaataca
    10861 gagattgctt tatatgaaat tggtcgggtg ttcttccaag aaaatgatcc acgtacacat
    10921 ctgccgcaag aagtaaaaca tgcagcaatc gctatttctg gtatttggga agaaaaagat
    10981 tggcagacga aagctcaaaa tgtagacttt ttcaccatca agggtctttt agaaaactta
    11041 tttgaacaac taggcatcac tgaagatgtc cattatcaaa cagtgacaga aatgaaggaa
    11101 atgcatcctg gaagaactgc tgcgatttac cttggcgaaa aatttattgg ttttgtcggt
    11161 caagtgcatc caacgattac aaaaagttat gatattccag aaacatatgt tgctgagttt
    11221 gatttatctg ctatagtgga agctgctcaa aaagggatcg ttttcgaagc agtgacaaaa
    11281 ttcccagcag tcagccggga catcgctttg cttgtaaaag aaactgtgac aaatcaggaa
    11341 ttaacagaag ttatccgttc tgctgccgga agatttttaa cagatatcca attatttgat
    11401 gtctatcaag gagaaaacat tgaaaaagga cataaatcca tggcgtatag cctgacattc
    11461 gtcaacccag aagcaacatt gacagatgaa gaaatcaata aagcaatgga aaaagtcgaa
    11521 aaagcgttgg tagaaaacct agaggcaagt attcgctaag aaggaaaata tagtaagtaa
    11581 cgatcaagta gcttttgaag accatacatt tgaaaaaaag atgtgacaca acttcgtcac
    11641 atctcttttt ttgattttaa aaaaggaata gcacagagac gagataaaaa aacaggcctt
    11701 tacagcctgc ttttttagag taaatgaatt aatggaagta attgattccc attgctgatt
    11761 ttacttcaga aagtgtttgt gcagctactt tagcagcttc ttcactacct ttacgtaaga
    11821 tttccataac agctgaagga tctttttcca attcttctcg gcgcgcacgg atcggtgcaa
    11881 attcagcttc caatacatca atgaggtatc gtttgatctt tacatcacca agtccgccgc
    11941 ggcggtaatg agctttcatt tcttcaattg cttctttatc tgttccgaat acatccaagt
    12001 aggtgaagac catattccct tctacttgtc caggatcttg tacatggatg tggtttggat
    12061 cagtatacat actcatgact tttttctgta agacatcggc aggatcggag atataaatac
    12121 cgtttcctaa cgatttactc attttgccat ttccatcgat tccaggtaat ctacccattc
    12181 cttttggtgg gaatacgcct tttggttcca ccaagacttc accatatgta tgattgaagc
    12241 tttgtacgat ttcctgtgtc tgctctagca ttggtttttg atcctcacca acaggtacaa
    12301 gattcgcttt gaatgcagtg atatctgctg cttgagaaac aggatagata aagaatcctg
    12361 taggcacgct ttcaccgaat tttttttgtt cgatttctgt tttgacagtc ggattgcgcc
    12421 gaacgcgtcc tacgctgact aagttcaaat aatacatggt taattcagct aattccggaa
    12481 tttgtgattg gataaataaa gtagattttg caggatctaa tcccacggct aaatagtcta
    12541 aagcaacttg caagacattt gatgaaacct tctcaggatt tttagcatta tctgtcagtg
    12601 cttgcatgtc agcaatcatg acaaacagtt ggttgtcttc atctgcctgc atagccactc
    12661 gggtttttag agaaccgacg taatgcccta aatgcagctt cccagttggt cgatctcccg
    12721 ttaaaataat atttttcaaa aaagacacct ctttacgatt tgtaagtctg agcacttaat
    12781 atcttaccgt ttttcctgaa aagaaacaac agttcctaag gaaaaaacaa ggaaagagga
    12841 taaaataact aatagattag aaatggaaga aatatttatg ggagaataaa cgttctaaga
    12901 aactttacaa attactaaac tatcagatat aatgtatttt attatacatc tttaaaagaa
    12961 atcttactaa ataataatgg gagtgtaatt ctatggcaat gattaaattt gatcacgtgg
    13021 ataaatatta tggcaagttc cacgcattaa aaaatatcaa tctcgaattc gagaaaggag
    13081 aagttgtcgt tgtcattggt ccttctggtt caggaaagag cacgatgctt cgctgtatca
    13141 atggattaga gacgatctct tcaggtaagc tgctgattaa tgatactgac ttgcatgata
    13201 aaaagacaaa actgacagaa gtccgaaaaa acatcggcat ggttttccaa catttcaatt
    13261 tgtacccaaa taaaactgtt ctggaaaaca tcaaattagc accaatcaaa gtgttgaagc
    13321 aagaccaggc aactgcagtc aaaaacgcgg agaaattttt gaaaactgtc aatatgttag
    13381 ataagaaaga ttcttatcct tccatgttat ccgggggaca acagcaacgg gtggcaatcg
    13441 ccagaggttt agcgatgaat cctgagatgc tgctgtttga tgaacctact tctgctttgg
    13501 atccggaaat gattggtgat gtattagacg ttatgaaaaa attggctcat gacggtatgt
    13561 caatgattgt cgtgacacat gaaatgggct ttgccaaaga agtggcggat cgtgttatct
    13621 tcatggctga tggagaagta ttggaagaca gcagaaatgt gagagacttt ttcgaaaatc
    13681 caaatgaagt ccgagcacag caatttatca gtaaagttat caatcattga taggaggaaa
    13741 aagatgcgca ggttaaaaaa aatacgcctg attttccttt taggcattgc ttttcttgca
    13801 ctagccggat gtaaaggaaa tgggttggca aatgaagata ttttagagcg aagcaaatct
    13861 accaatgaaa tcatctgggg tgtcaagtat gatactcgat tatttggaat gatggatatt
    13921 gagagcagaa ctgtacaagg atttgatgta gatattgcaa aagcaatcac taaaaagatc
    13981 cttggtgaca atggaaaaac agaatttgtt gaagtcactt ctaaaactcg gattccatta
    14041 ttgaaaaacg gaaatatcga tgcaattatt gcaacgatga cgatcacaga tgaacgaaaa
    14101 aaacaggttg acttttcaga tgtctatttc gatgctggcc aagctttgtt ggtaaagaaa
    14161 ggaagccaaa tcaaaagtgt agatgatttg aatgcttcta caacggttct agcagtcaaa
    14221 ggttctacat cggctgcgaa tatccgacag catgcaccag atgcaaaaat tttagaatta
    14281 gaaaactatg cagaagcatt tactgcttta caatctggtc agggagacgc gatgactacg
    14341 gataatgcga ttttgttagg gattgcagat gaaaatccag agtatgagtt agttggtgga
    14401 acgtttacta atgagcctta cgggattgcg atcaacaaag ggcaagaaaa cttcttgaaa
    14461 gctgttaacc aagcgctaga ggaaatgcat gcagatggca catacgataa aatctatcaa
    14521 aaatggtttc caaatgaaac tgaaggaaaa gtagagtaag ggggagaggc aatgagcgaa
    14581 ttgatacaaa cttatggacc aatctttgtc gacgggttca agatcacatt gttttcgagt
    14641 gtcttagcac ttgtgtttag tttgattatc ggaacgttaa tggcaatctt ccaattatca
    14701 aagaataaag tagtgagcgc cttagcaaag gcatatgtag aattttttag aaacattcca
    14761 ttattaatca tcgtgatgtt tttttatgtt gtcgtaccga tttattggtt taatctagat
    14821 ggattccaag caggtacgat tggattaacg atctatacat ctgcttttat tgctgaaaca
    14881 gtacgttcag ggattcaaac cgtaccaaaa ggtcaaacag aagcaggact atcttctggt
    14941 tttacctatt cagaaatcat gcgttatatt gttttaccgc aagcattcaa aatcgttatc
    15001 ccgccattag gcaaccaatt tatcaacctc gtaaaaaact catctatttt agcaatcgta
    15061 gctggtttag atttgatgta tcaaggagac ttgatcgcta gtgaaacatt caataccttc
    15121 gatacgtata tcatcgttgg gttattttac ttagttatca cgctaccgtt atcttactta
    15181 atggtttatc ttgagaaaaa atgggcggtt cgttcataga aggaggggaa atacatggat
    15241 tttagcggcg ctttttcatg gatgaatatc cgttttttat tggaaggatt aaaggttact
    15301 gttgaagttt cattgttttc gatcattttt agtttcttga tcggtggtct gacaggtgtg
    15361 attcgttttg cgaatatccc tttcttttcc aaaatccttg gtgtagtgat tgatattata
    15421 cggaatcttc cattattatt gatcattttc ttcacttact ttgccttacc tcaaatcggc
    15481 attcagatga acatcttctg gtccgctgtc gcagcattaa cgatttttga gtcagctatg
    15541 ttgtcggaaa ttttccgagc tggactcaat gctgttccaa aaggacagat ggaagcagga
    15601 ttatcaacgg gactgactta tgtagaatcg atgcgaacga tcgtgttacc gcaagcattt
    15661 aaatcaatga tcccggcaat tgtgagccaa ttgatttcac tgatcaaaga tacttcatta
    15721 gcagtaatca tttctttacc tgaactttct catcaggcac gtattattta tggacagaac
    15781 accaattatg tgcttccgat gttcatcatc atgacactta tgtacttcgt ggtatgttac
    15841 gcgctttctc tgctttccgg ttacttggaa aagagacggt acagttatta atagatgatt
    15901 cttttagcgg ttgtggcaaa ctaaagtcac aaccgctttt cctctttcca ttcgaaaaaa
    15961 agagatttcg attgttttaa gcaagtaaga gcacttgaaa attcacgcta aaaagtacac
    16021 aatagggagg atagaattta ttgaaaaaaa ggatgatacg attgacagat aatcgcccta
    16081 tcggatttat tgattcaggt gtcggcggct tgactgtagt aaaagaagcc ctgaaacaat
    16141 taccgaatga aaatatttta tttgtaggag acacagcacg ctgcccatat ggccctagac
    16201 ccgcggaaca ggtaatccag tatacttggg aaatgacgga ttatctggtg gagcaaggaa
    16261 tcaagatgct ggtgatcgcc tgcaataccg caactgcggt ggctttagaa gaaatcaaag
    16321 ctgctctttc tattccagtc atcggtgtga tccttcccgg tactagagcg gcagtaaaaa
    16381 aaacacaaaa taaacaagtt ggcattatcg gtacgattgg tacggtaaaa agtcaagctt
    16441 atgaaaaagc actgaaagag aaagtaccag aattgactgt gacaagtctt gcttgtccca
    16501 aatttgtttc agttgtcgaa agtaatgaat accattcatc ggtggcgaaa aaaattgtgg
    16561 cagaaacatt agctccttta accactaaaa aaatcgatac attgattttg ggatgcaccc
    16621 attatccatt attacgcccc atcattcaaa atgtaatggg agaaaatgtt caactgatcg
    16681 attctggagc agaaacagta ggtgaagtat ctatgctgtt agattatttc aatttgagca
    16741 attcaccgca aaatggtcgg acattatgcc agttttatac aactggctct gccaaacttt
    16801 tcgaggaaat agctgaagac tggcttggaa tcggacactt aaatgtagaa catatcgaat
    16861 tgggaggaaa ataaggatgc gtcatgacgg gagaaaagcc caagagcttc gcaaactgga
    16921 gcttcaaaca aatgttttca aatatccaga aggatcggta gtgatccgtt ttggtgatac
    16981 aacagttatt tgttctgcaa caatagaaaa ttctgttccc ccttttttga gagaaacagg
    17041 aacaggatgg gtgacagcag aatatagtat gctgcctcga gcaacgagta cgagaaatcg
    17101 tagagaaagc agcaaaggga aactttctgg tagaacaatg gaaatccagc gtcttattgg
    17161 tcgttccttg cgtgcagtag tagacttgga aaaattagga gaacgtagta tcatcgtaga
    17221 ctgcgatgtg atccaagcgg atggcggtac tagaacagca agtatcactg gggcatttgt
    17281 ggcattgaaa ttagccattg aaaaactttt aagagaaaaa gaattgtcag aagatccaat
    17341 aaaagaacat cttgctgcag ttagcgtagg aatcttacca gatgggactt gcgtcacaga
    17401 tttggattac caagaagatt ccgcagcact tgtagacatg aatcttgtaa tgacagaatc
    17461 tggaaaattc gtggagattc aaggaactgg agaagaagca acgtttgatg gtgaacagtt
    17521 gaatgaaatg ctcttttttg gaaaaaacgc gattgaagat ttgatcaaag agcaaaaaca
    17581 tgctttgcta acagagtttg ctcaaaatga tgagcggata gaagaaacaa aaacaatcat
    17641 cattgcgaca agaaatccag gaaaagcaga agagtttcga aatatgttca aagaagcggg
    17701 atatcatgta aaaacattac ttgactatcc tgaattgcca gatgtggaag aaactggcag
    17761 cacatttgaa gaaaatgccc gattaaaagc agaaacgatt gcacaattgc ttgatcagcc
    17821 agtcttagca gatgattcag gtttgaaagt ggatgcttta ggcggtatgc caggaatcta
    17881 ttctgcacgt tttgcagggg aacaaaaaag tgatgcgggg aataacgcca aattattata
    17941 tgaattgaca gatgtgccgg atgaaaaaag aacagcacaa ttccattgta cgttagtatt
    18001 cgcggcaccc aaaaaagaca gccttgtagt agaagcggaa tggcccggtc gagtagcccg
    18061 tataccatct ggcgaaaatg gctttgggta tgatccttta tttatcccag aaggtaagaa
    18121 acaaacagca gcagaattat cgagcgaaga aaaaaacaag atcagtcatc gggctcaagc
    18181 aatgaaaaaa ttgagtgccg agtggaaaca atggctggaa ggagagagat agatgcggta
    18241 tttagtagta agtgataatc atggagacag agatatcctc gttgacttag tagatcgtta
    18301 tcgttctgaa gtggatatct ttttccattg tggtgattcg gaattagaag cttctgaccc
    18361 attatgggat acattccaag tggttcaagg taattgtgat tatggaccag gattcgaaca
    18421 gaaaaaagtg atccaaactg gtcaggatac agtattcatg actcacggtc atttatcgaa
    18481 tgtccgattt ggtttgacac agttagcaat cgaagctcga gctgcaactg ccgatatggt
    18541 gttttttggt catacccatc aaataggctg tgagatggat cagaaaatcc tgtttttgaa
    18601 tcctggtagc atttctcagc ctagaggccc gatccaaatc ccatcatatg ctcttatcga
    18661 aagtttagat gaccaaattt ctgttcaata ctataaccgt gcccatcagg cagttgaaga
    18721 gttggccttt tctttttcga gagagcgctg aataaaaaaa ctctaatttt taataaaaat
    18781 aagctttatt ttatgaattt tgcatccggt ttcggtaaaa tagtagtgtt gaatgaaata
    18841 gaaatggagg ccatcagatg attggaccta tagtaagaga aatgctgctg gaaaatcagg
    18901 aaacgttttt gattcctgca gaaaatgtgg caaatgttat gtatcatcat ccattgtccc
    18961 atggtttact tgtgttatcg aaggtcggtt attccaaaat tcctgtatta ggaaaagatg
    19021 atcactttgt aggactagta agtttatcag atgtggtcaa taaaatgatt gacttgcaaa
    19081 caatcagcat ggacccgtta gaaggactaa cggttgctga tgtgacagaa acagatgttc
    19141 cgacaattga tgaaaattgg gaactagaag aagtactcca tttgttagtc gattcgcctt
    19201 ttttaccggt tgtcacagaa gatcggattt tcaaaggaat cattacaaga aaagagctgc
    19261 ttaaagccgt aaacttcatg gtgcatgaat tagaacgtcg taatatattg tctccgaaaa
    19321 tcgaagaatt aaaagaacaa atcgatatcg tgagctaaag aacgagaaac taaaagataa
    19381 tcaaaaaata agtagaaaaa acagcgtacc agttttgact ttatcttgaa aaagaggctg
    19441 ggacaaaagc gtttaactcc aagaaataag aaggaattca cgaaaattgc ttttcaaatt
    19501 tttgtgaatt tcagcttatt tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt
    19561 tagagcgtgg gacaaaagtg ttctttactt ttgtcccacg ctctttttag tgagattcgt
    19621 tgcatcgttt gtccaaatta ttttccgaca gcaattggac tgttcggaat cgtgaaacca
    19681 gaagctgtca attctttgac ataggagctc aagaactctt cttttaaggc atattgtttt
    19741 ccgttcaatg cgtagcagac cgtacgaatc gcaaaattgc tgtttccaag atccactaat
    19801 ccaaagatag aaggttcagt ttggagctct tcttggtatt tttcagctaa tgtacgattt
    19861 actcgatcaa tgatctcata gattttgtca tatccttctt caggaacaat ccgaatatct
    19921 aaaagtactt gcatatttgc acgagagaga ttgctgatcg tggtgatgtt tcgattcggg
    19981 atgaaatgga cagtaccatc cgttgctttc agctgaaggg tacggatacc aacagatacg
    20041 acggttcctt caatcgttaa gtttgctagc ttgatgtagt ccccaacatc catctgttgt
    20101 tccatgataa taaaaaatcc ggtaataaca tcactcatga acccttgggc accaagaccg
    20161 attgccacac ctgcaattcc ggcaccagcc aaaagtgatc cgatcggcac accgatagca
    20221 gataaaattg catagataaa aaagaaacca agggtataat gaaaaatagt atttaaaaga
    20281 ctatgtaaag tctttaagcg gctctcgttt agaatggctt ttttagaata ctgattaaaa
    20341 gacttatcaa tcagatattt tcccacacgg tgaagaatcc aaaaaaggac gatcaaaaaa
    20401 atcagatata aacttttttg gataaaggca gccaaaatgg cgtcccaatc aatcccgtcc
    20461 caaaaccgct gaaacgcatt tactttgctg acagcttgat ctgtcaatgt ctcgccagaa
    20521 gagtctgtcg taccggcagt tgctaataat gaaaacataa aatcctcttt tctaaaattt
    20581 gattctttct gtattgtacc aagaagtttt caaaaaagga aatagcaaaa ataactataa
    20641 tgaaggaaaa aagctgaaaa taaaatgaca aataatatgg ataatgataa aatgtggaga
    20701 aaataacgaa ggtggtaagt atatgcaaat cgattggaac aatctaggtt tttcttatat
    20761 caaaactcct tggcgtttta ttgccaaatg gaaagacgga caatgggaag aaggagaatt
    20821 gacagaagat aattacctga cgattcatga aggctctcca gcgcttcatt atggtcagca
    20881 atgttttgaa ggtctaaaag cttatcgtcg aaaagacggc aaggtcaatc tctttcgacc
    20941 tgaacaaaat agtcgacgga tgaatcaaag tgctagacga ttgctgatgc caatggtccc
    21001 tgaaaagatg ttcgttgatg ctgtcaagca agtggtaaaa gcaaatgaag attttgtgcc
    21061 gccctatgga acaggcgcta cattatactt gcgcccttta ctgattgggg tcggtgaaaa
    21121 cattggtgtc catccagctc cagaatattt atttgtcgtc ttctgtacgc cagtaggagc
    21181 gtatttcaaa ggtggactaa aaccaacgaa ttttattgta tctgattacg atcgtgctgc
    21241 tcctaagggg actggtgcag caaaagtcgg cggaaattac gcagcgagtt tacttccagg
    21301 aacagaagca aaagaactgg attactcaga ttgtgtttat cttgatccag ccacacatac
    21361 gaaaatcgaa gaagtaggtg cagcaaattt ctttggaatt acaaaagacg gaaaattcat
    21421 cactccgcaa tcgccctcta tcttaccaag tatcacgaaa tattccttgt tgcagttagc
    21481 tgaagaacga ctaggactgc aagcaattga aggagatatt ttcattgatg atctagatca
    21541 atttgcagaa gctggtgcat gtggtacagc ggctgttatt tctccaatcg gtgggattta
    21601 tcacaataac aatcttcatg tattttatag tgaaacggaa gtaggaccag taacaaaacg
    21661 gttgtatgat gaattgacag gtattcaatt tggagacata gaagcaccag aaggctggat
    21721 tgaagtcgtg gaataatttc aaagtaatga gttgaaaaaa acgtaaaaag aaaaaatcag
    21781 gaagagactt taaaaagttt tttcctgatt tttatatgtt ttactttaaa gaatgcaaca
    21841 aaagtttatg aaagatggac acctttgtca acgtagataa tatcaccgat gattccgctg
    21901 gaaagtgggc tgattaagaa agcacaagca ttaccgactt cttcgatcgt cacaccttgc
    21961 tgatcaggcg tacgagattc agataactgg atcagttttt gatagtcttt aacacctgtg
    22021 acagctaatg ttttgattgc cccagctgag attccattga cccgaattcc tttaggcgag
    22081 aactcagctg ccaaataacg gatagcagct tcaagagaag ctttcgcaat acccatcatg
    22141 ttataattcg ggattgcgcg ttctgaacct agataagtca tgctaacgat cccgctgttt
    22201 ggtgcaagaa acggttgtgc gtattttgat acagcaatta aagagtagct gctgatatct
    22261 tgagctaatt gatagccgtc tctggaaata tcagacacat ttccggacaa ttcttctttg
    22321 ttggcgtaag caactgcatg gacaaggccg tggatctccc cagcatattc accgatggca
    22381 ttcattgctt tttcgatgct ttcgtcgcta gaaacatcac attctacagt gaatgcttct
    22441 tcgccgacca atttgactaa tgattttttc attcgttcat tttggtaagt atagataatt
    22501 tctgcccctt gtttcaacat tgcttcagca caaccccaag caatgctttt tttgttagcg
    22561 acgcccataa tgacgatttt ttttccttct agaaatgaca taatgactct cctttgtttc
    22621 tgataaaaat ttgatagtcg taaaaaaata gagaataata gctaaaataa cttcttgatt
    22681 tcttaattat tagtcaaaat gttttgattg tcaaactatt ttttcttaaa ttaaaaaaag
    22741 attgctaaat atttaggaat atgatacttt gatagtcaaa gtaatgataa tggcaattgc
    22801 ctgaaagaag gagtttaatt atgtcttacg tattatctgc tactgaagta atggaattga
    22861 ttcctaatcg ttatcctatt tgttatattg attatgtaga tactttagaa ccaggaaaaa
    22921 agatcgttgc gacaaaaaat gtaacaatca atgaagattt tttccaaggt cactttcctg
    22981 acaatccagt gatgccgggt gcgttgattc tagaaacact ggcacaagca ggttcgatac
    23041 ttatcctaaa atcagaagag tttctaggaa aaagagctta tatcggtggg atcaataagg
    23101 ccaaattccg tcaaaaagtt gttccaggag atgtgctgaa atgtcatttt gaaatcacca
    23161 aaatgaaggg atcagtcggt acagcgttat ctgcagcata tgtagatgat aaaaaagtct
    23221 gtgagtgcga gttcacgttc atcgtcaacc aaaatgcttg actataaaac ctgatatagc
    23281 aaaacaaaag gaagcttact tgctttttat gtaaaaagaa gacgcctgaa tcctagcata
    23341 cgttgtcatc tatgcaggat tcagacgtta tttttttatt tttgttttgc ttcttgcagt
    23401 atattgattt tatcgatttt tacttcttct tttggtttgt ctgaactatc tgtttcgata
    23461 tttgcaatag catccacgac atccattcct tcaatcactt ggccgaagac agtataatgg
    23521 ccatctagtg aaggataacc gccgttttta taagcgtcga tgattgcttg aggatagtcg
    23581 tcttttaaaa gaccatcatg catatcatct gtattttgaa cgataaagaa ctggctgccg
    23641 ttactgttag gatcttgtga gcgagccata gataacgcac ctcttatatt ataaaggtgg
    23701 ttgttgatct ctgtttcaaa tccttctccc caaatgcttt cccctccagt gccatcgcct
    23761 ttaggatcgc caccttggat catgaaatct ttgatgacgc gatggaaagt cagtccgttg
    23821 tagtaaccgt cttttgcatg tgtcataaag ttttcaaccg cttttggtgc gtgttcggga
    23881 aataatttga ttttgattgt gcctttattc gtcaccattt cgaccagatc ttcattttcg
    23941 gcgacatctt tcgtcaattg tggtaattcc aatgcgttca aatcgacgct actggcagtc
    24001 gtgctttccg cagtagatgt actttttgaa ctttctgtag acgaactaga agaagtcgtg
    24061 ttgtttgcag aacaaccagc agcaaacagc aatgctgctg ctaaactaat acttaaaata
    24121 actttatttt tcttcataac tgttcctttc caatttacta ttttgttatc tttaatgata
    24181 acaaaataga gggaaaatac ctacttaaat tattggaatt tatcatttat tttaaaagaa
    24241 aaagaaaagg tgtagaccat ttactttgtg tttgctataa tgtaagtgga tacaaaaacg
    24301 aaaagatgca ggaggaaatg gtaatatggg aaaattagga atctcgattt atccagaacg
    24361 gtcaacattt gaaaaggaca aagcgtactt ggatttagct cataagtatg ggtataaacg
    24421 ggtttttacc agtttgctgc agatcaatga tgataaagaa aaagttcttt cagaatttaa
    24481 agaagtagtt gattacgcga atagcctagg catggaagta atggttgata tcaatccagc
    24541 gttatttgaa cagttggaga tttcttacga tgacttatct tttttccata agatgggtgc
    24601 ctacggggtc cgcttagata tcggattcac aggagcagaa gaagcaaaaa tgacgcgcaa
    24661 tccttttggt atcaaaatcg agatcaatat gagttcgggc acgaattacg ttgacaacat
    24721 catgagttat tcgccaaaca cggataattt attaggttct cataattttt atcctcatcg
    24781 atactctggt ttaggatacg aacactttgt tttttgttca gaaaaattca gaaaatataa
    24841 tttgaatacg atggcattcg tcaattcgca atctgctgag tttggccctt ggcctacgca
    24901 agatggcttg tgcacgctgg aagaccaccg agatcttgaa attgcgacac aagtgaagca
    24961 tttaatcctt acaggattga ttgatgatat ttctattgga aatgcgtacg caagtgaaga
    25021 agaattgaaa gaaatggcag aagcatttaa cgcggattat ccaacattga aagtagatac
    25081 ggaagaaggt attacagaaa acgaacgaat ctgcttgttt gataaccttc atagttatcg
    25141 aggggatcgc tcagaatata tccttcgttc aacgatgact cgtgtatact acaaagataa
    25201 agatttcccg cctcataata cgcgagatat gcatcatggg gatgtactga ttgacaatga
    25261 agggtacggt caatacaaag gagaaacaca aatcgccttg aaggatatga aaaacgacgg
    25321 acgtgtcaat gttgtaggaa gaatctccga tgacgaatta ttcctccttg actttttgaa
    25381 accatggtca agctttaaat taattgaaaa taaaaaatag ataattagtt attgcagaaa
    25441 taatccgcta gaaatagcca gttatttctg cttttttatt ttgttttttt ataggttatg
    25501 atttgtcaaa ttaagctaga ataaaatgct tcttgtacat agctcaaaaa tatttcgatt
    25561 ggtgttctgt aattcaatga ttttcttgga atatgattac gttgattgct gacactggaa
    25621 ataaatgtct gattcacttt tctaaaatcc attgatttcg gcagtccatt acgacgcaga
    25681 atcccgttag aattctcgtt taatgggcgt tgagaaggtg ttccagggtc cgcaaaatat
    25741 atatcaatat catgttggtt actaatggct ttccagttag aaaattcttt tccacagtca
    25801 aacgtaatag atttaaagaa gtttttaggg aagcgagaaa accattgatt aagggcagtt
    25861 tcaatatcta atgccttacg gccgttgggt ttaatcgtga taatgacttt agataatctt
    25921 tcaactaaag taatgacggc acttttatga tgaatgccaa cgatcgtatc accttcaagg
    25981 tgaccaaact cagaattgaa atcaggataa ttatcaggtc gatcatggat tgagcgctga
    26041 tactgttgtt ttccccgttt ttcctgatgg ccattgggtt ttcttttacc tttcatcggt
    26101 agtgtgtcaa tatcaaatat tcctttagaa aataaacgat aaagtg
//
LOCUS       DASHWW010000031        25819 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.031, whole genome shotgun sequence.
ACCESSION   DASHWW010000031 DASHWW010000000
VERSION     DASHWW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.031"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(451..1761)
                     /locus_tag="U2R64_001525"
     CDS             complement(451..1761)
                     /locus_tag="U2R64_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEM8918348.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="U2R64_001526"
     CDS             complement(1773..3191)
                     /locus_tag="U2R64_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8918349.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="U2R64_001527"
     CDS             complement(3431..4999)
                     /locus_tag="U2R64_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEM8918350.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="U2R64_001528"
     CDS             complement(5003..5413)
                     /locus_tag="U2R64_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HEM8918351.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="U2R64_001529"
     CDS             complement(5410..6333)
                     /locus_tag="U2R64_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HEM8918352.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="U2R64_001530"
     CDS             complement(6330..7208)
                     /locus_tag="U2R64_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HEM8918353.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="U2R64_001531"
     CDS             complement(7195..8532)
                     /locus_tag="U2R64_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEM8918354.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="U2R64_001532"
     CDS             complement(8535..9638)
                     /locus_tag="U2R64_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEM8918355.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="U2R64_001533"
     CDS             complement(9712..11220)
                     /locus_tag="U2R64_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8918356.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="U2R64_001534"
     CDS             complement(11186..11878)
                     /locus_tag="U2R64_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEM8918357.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="U2R64_001535"
     CDS             complement(11900..12874)
                     /locus_tag="U2R64_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918358.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="U2R64_001536"
     CDS             13174..14046
                     /locus_tag="U2R64_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8918359.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="U2R64_001537"
     CDS             complement(14504..16702)
                     /locus_tag="U2R64_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918360.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="U2R64_001538"
     CDS             16934..17926
                     /locus_tag="U2R64_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8918361.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="U2R64_001539"
     CDS             17986..19407
                     /locus_tag="U2R64_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HEM8918362.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="U2R64_001540"
     CDS             19400..20899
                     /locus_tag="U2R64_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HEM8918363.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="U2R64_001541"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="U2R64_001541"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEM8918364.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="U2R64_001542"
     CDS             22491..23174
                     /locus_tag="U2R64_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HEM8918365.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="U2R64_001543"
     CDS             23176..24012
                     /locus_tag="U2R64_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEM8918366.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="U2R64_001544"
     CDS             24023..25777
                     /locus_tag="U2R64_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918367.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
BASE COUNT         7858 a         5246 c         4525 g         8190 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaatttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcctccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctccta
//
LOCUS       DASHWW010000032        25807 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.032, whole genome shotgun sequence.
ACCESSION   DASHWW010000032 DASHWW010000000
VERSION     DASHWW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.032"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..848
                     /locus_tag="U2R64_001545"
     CDS             6..848
                     /locus_tag="U2R64_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEM8918368.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            848..1795
                     /locus_tag="U2R64_001546"
     CDS             848..1795
                     /locus_tag="U2R64_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEM8918369.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1810..2043
                     /locus_tag="U2R64_001547"
     CDS             1810..2043
                     /locus_tag="U2R64_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HEM8918370.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2374..2958
                     /locus_tag="U2R64_001548"
     CDS             2374..2958
                     /locus_tag="U2R64_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8918371.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3089..3757
                     /locus_tag="U2R64_001549"
     CDS             3089..3757
                     /locus_tag="U2R64_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEM8918372.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            3768..5183
                     /locus_tag="U2R64_001550"
     CDS             3768..5183
                     /locus_tag="U2R64_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8918373.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            5201..5770
                     /locus_tag="U2R64_001551"
     CDS             5201..5770
                     /locus_tag="U2R64_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEM8918374.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5880..7634
                     /locus_tag="U2R64_001552"
     CDS             5880..7634
                     /locus_tag="U2R64_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918375.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7594..9360
                     /locus_tag="U2R64_001553"
     CDS             7594..9360
                     /locus_tag="U2R64_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918376.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            9883..10152
                     /gene="rpsN"
                     /locus_tag="U2R64_001554"
     CDS             9883..10152
                     /gene="rpsN"
                     /locus_tag="U2R64_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEM8918377.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            10167..10346
                     /gene="rpmF"
                     /locus_tag="U2R64_001555"
     CDS             10167..10346
                     /gene="rpmF"
                     /locus_tag="U2R64_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEM8918378.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            10378..10755
                     /locus_tag="U2R64_001556"
     CDS             10378..10755
                     /locus_tag="U2R64_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918379.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            10776..10925
                     /gene="rpmG"
                     /locus_tag="U2R64_001557"
     CDS             10776..10925
                     /gene="rpmG"
                     /locus_tag="U2R64_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEM8918380.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            10949..11932
                     /locus_tag="U2R64_001558"
     CDS             10949..11932
                     /locus_tag="U2R64_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEM8918381.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            11962..12084
                     /locus_tag="U2R64_001559"
     CDS             11962..12084
                     /locus_tag="U2R64_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEM8918382.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            12102..13625
                     /locus_tag="U2R64_001560"
     CDS             12102..13625
                     /locus_tag="U2R64_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEM8918383.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFRDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            13649..13888
                     /locus_tag="U2R64_001561"
     CDS             13649..13888
                     /locus_tag="U2R64_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918384.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(14081..14542)
                     /locus_tag="U2R64_001562"
     CDS             complement(14081..14542)
                     /locus_tag="U2R64_001562"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8918385.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(14737..14955)
                     /locus_tag="U2R64_001563"
     CDS             complement(14737..14955)
                     /locus_tag="U2R64_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918386.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            15073..16689
                     /locus_tag="U2R64_001564"
     CDS             15073..16689
                     /locus_tag="U2R64_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEM8918387.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(16930..18270)
                     /locus_tag="U2R64_001565"
                     /pseudo
     CDS             complement(16930..18270)
                     /locus_tag="U2R64_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18546..18701)
                     /locus_tag="U2R64_001566"
     CDS             complement(18546..18701)
                     /locus_tag="U2R64_001566"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEM8918388.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(18997..19329)
                     /locus_tag="U2R64_001567"
     CDS             complement(18997..19329)
                     /locus_tag="U2R64_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8918389.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(19843..20034)
                     /locus_tag="U2R64_001568"
     CDS             complement(19843..20034)
                     /locus_tag="U2R64_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918390.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(20128..20514)
                     /locus_tag="U2R64_001569"
     CDS             complement(20128..20514)
                     /locus_tag="U2R64_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8918391.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            21208..22413
                     /locus_tag="U2R64_001570"
     CDS             21208..22413
                     /locus_tag="U2R64_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEM8918392.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            22430..22864
                     /locus_tag="U2R64_001571"
     CDS             22430..22864
                     /locus_tag="U2R64_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918393.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            23481..>25807
                     /gene="esp"
                     /locus_tag="U2R64_001572"
     CDS             23481..>25807
                     /gene="esp"
                     /locus_tag="U2R64_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HEM8918394.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         8893 a         3698 c         4831 g         8385 t
ORIGIN      
        1 ataatatgct tcaaaatttt attaatggtc tgtatgactt tcacttttta cagaatgctc
       61 taattacatc tgtagttata gggattgttt ctggaacagt aggttgtttt attattttaa
      121 gaggaatgtc tcttatgggt gatgctattt ctcatgctgt tttgccagga gtagcaattt
      181 cttatatttt aggtattaat ttttttattg gtgcgattgt atttggtcta ttagcttcta
      241 tcattattac ttttataaaa agcaatagtg taataaaagg agatacagca attggtatta
      301 ctttcagttc ttttttagca ttaggagtta tccttatagg agttgcaaat agctcaacgg
      361 atttatttca tatcttattt ggaaatattt tagctgtaca agatattgat aagtggatta
      421 caattggcgt ttctgtttta gtgttggtta cagttgttct attttttaaa gaattattaa
      481 tcacttcttt tgatccatta atggcaaaag caatggggat gaatgtcagt ttttatcatt
      541 atctattaat gattctatta actttagtag cagtaacagc tatgcaaagt gtgggaacta
      601 tattaattgt tgcaatgtta attacaccag ctgctacagc atatttatat gcaaacagct
      661 taaaaactat gatatttatt tcggcgacag tcggagcgtg ctcatcattg ctaggtttgt
      721 tcattggtta tagttttaac atagcagcag gatcaagtat tgttttaaca gcggcattct
      781 tatttgtaat tagttttcta atctcaccaa aacaaaaatt tttaagaaag aaggagagaa
      841 agttatgatg agaaaatgga aagcagtact gggaagtctg gggattttga ttgctctttt
      901 tatattcggg gcatgttcaa caaatagtaa agacaaagat acagtggctt cgaacgaaaa
      961 attaaaggta gtagttacta attcgatttt agcagatatt actgaaaata tagcaaaaga
     1021 taaaattgat ttacacagta tcgtacctat tgggaaagat ccccacgaat atgaaccttt
     1081 gcctgaagat gttcaaaaaa cttcaaaagc agatttgatt ttttataacg gtgttaactt
     1141 ggaaactgga ggaaatgctt ggtttacaaa attagtaaaa aatgcgaaca aagaggaaaa
     1201 caaagactat tttgcagcaa gtgatggcat agatgttatt tacttagagg gtcagagtga
     1261 gaaagggaag gaagatcccc atgcttggtt aaatttagaa aacggtatta tttacgctaa
     1321 aaatattgaa aaacagttag cggaaaaaga tcctgataat aaaaaattct ataaagaaaa
     1381 tctagataag tatattgaaa aattggattc tctagacaaa gaagctaaat ctaaatttgc
     1441 ttcaattccg aatgataaaa aaatgattgt tacaagtgaa ggatgcttta aatatttctc
     1501 gaaagcgtat aatgtgcctt ctgcttacat ttgggaaatc aacactgaag aagaaggaac
     1561 accagatcaa ataaaacact tagttgaaaa attacgcaca acaaaagttc cctccttatt
     1621 cgtagaaagc agtgtggacg atagaccaat gaaaacagta tcaaaagata ccaatattcc
     1681 tatctattca acgattttta ctgattcaat tgcagaaaaa ggacaagatg gtgatagtta
     1741 ctatgcgatg atgaaatgga acctggataa aattgctgaa ggcctttcga aataatttgg
     1801 agggtaggta tggtacaaat taaaacgact actatactaa tttatttact agcaattcag
     1861 gaattatcaa aaagaaaaaa gaaattaaaa aataatgatt tagcaaaagt tctaagtgtt
     1921 agtccagcat ctgtaagtga gatgctggct aaacttagat atgaggacta tttagatata
     1981 ggatttcaat taactgataa agggaaaaaa tttattgacg attacaaaaa aggttttaag
     2041 taaaagactt tatttttagg gaggataaga aaatggctat tggagtgatt atgataggac
     2101 ttaccctaat agctggatat aattttttta aatctttctc ggattatttt agaaaaggtg
     2161 aatgatttag atgagtctat taattcttgt aggattgctt tttgtatcag ttattttgct
     2221 ctttctcatt agtttagctc taaggaatga gttcagtaat agacgttaac gattgaaact
     2281 tcaagtcctg tgtaagataa tatagttaat tcatcttatt aggaggaagt acccatagaa
     2341 accagagatt atattacaac tcaccaaaaa ttaatagaaa gtggactaag ccattttgaa
     2401 aaagaaggat ttcagcaaac taagataagg caactgtgct tgaccgcagg cgtaactacg
     2461 ggtgcttttt ataaacattt tacttctaag gaagcgttat ttgaagaaat tattcagccg
     2521 catattaatg cgcttattaa tatgtataat gaagagttta ccaaatacct cttaaactta
     2581 gaaaatatag atatagagaa aagttggaga gagaacttca atgaattaga tccatttatt
     2641 aattatattt ttgagaataa acgtatattc gatttggttt tattccaatc agctggaacc
     2701 aaatatcaag atattgttga aaaaattaca tcatttgtga caaaaaagac agtctgttgt
     2761 ctagataagt taaagactat cggaatgatc aatcaaaatt tagtctttaa tgaagaagaa
     2821 atccacttct acatttactc attctacgct acattctatg atatattgaa gcatagctat
     2881 tcaaaagaaa agactatgct attaaccaga agattgtatc aattttctgt tcctgggtgg
     2941 attgaattac tgagttaatt aaaaaaaagc ttgcattgag aattgttctc agttatgctt
     3001 tttgataaga tcgcactgtt atctgaataa cggtgcattt ttgtcagctt aagataacag
     3061 tgcgatctta ttttttggag gtgaaagagt gtcaaaaatc aatccgttaa ccttgattac
     3121 tttaaatatt ttttttccgg tcattatttt tttaggaaag ggaaatatat ttcaagtggg
     3181 gtgtttcatt attgctacag ttttagtatt gatgtttcgt aaaataaaga catgtattta
     3241 tttcatcttg atttattcag ttctgttttt agtaatgaaa attattgatg ctatcaagat
     3301 agagtttttt actatatttt ttgggacatc cttatatatt gtatttcgaa tgttgccggt
     3361 cgtaatgatc tcatggttgt tggttagtgt ctatactagc aatgaattat tatcctcttt
     3421 agaaaaaata catttaccga aaaaaataat gttaagtatt acagtagtga tcagattctt
     3481 tccgacttat cgttctgaaa taagaatgat taaagaatct ttaaaaatga gaaacattcg
     3541 cttgtctttt tttcagcctc tgcaatattt ggaatttctg ttagttcccg ttcttatacg
     3601 tgcaactatg attgctgaag aaatgaccgc taatgcaata acaaagggga tagaatctcc
     3661 tgtgaaaaga agttcttact ataaaacaaa catgagctta ttagactata tcatcctgtt
     3721 ttccgttact atttttttct taagtatttt gatttgaggt gaaagaattg tttgaattta
     3781 acaatgtttc tttttcatat aaggatgtta aggaacaagc gcttgttgac cttaattttt
     3841 caataaaaaa aggcagtctt acattgatta ctggttcttc tgggagtggg aaatccacac
     3901 tattaaagtt aatgaatgga cttattccaa gactttatga cggaaaattg gttggggaaa
     3961 ttttatttga aaataactcg ctacaatcct taacacaaga aagtatatca aaaaatattg
     4021 gctacgtaag tcaaaatcct agaggacaat tctttacaac aaatacaacg agtgagttag
     4081 tattttcgat ggaaaacttt ggatttacaa aagagcatat ggataaaaga atcaatgaat
     4141 tagctgaatt attagatctt tcaaatatat tagataaaaa cattttttcg ctatcaagtg
     4201 gtgaacggca gaaaatttct attggatgta gtttatcgct aaactctaaa ttaattatat
     4261 tggatgaacc gtcttcaaat ttggacttca aagcgactaa gaaacttgct gacttacttt
     4321 gtgatttaaa aaataaagga tttactattg ttatagctga acatcgtttt tactatttga
     4381 aagaattaat tgatcaagtt ctatttgtta aaaatagaac tgtaaaaact acaactattc
     4441 agttgttaaa aactgaaaac aataacgcat taaggaaatt tgacattttt aatagttcga
     4501 ttgaagttcc ctatatcgaa aaggtaagtg cagatgtatt aaaagttgaa gaaattactt
     4561 atgaaaatat tctaaaagac ataaattttg atgtcaaagt tggagatgtt attggtttgg
     4621 tagggaaaaa cggtgtgggg aaaacaacct tactaagaat actcatgaag attattcgcc
     4681 ctaccaaagg aaagataatc gaaaataaaa aaaatttgtc atcgccgttt ttagtaatgc
     4741 aagaaatgga ttaccaattt ttcacagaat cagtgaggag cgagttagcc ctggggaatg
     4801 aaatagttag taaagatcag caagaaaaaa ttttaaaaaa aatggaactt tataaaatga
     4861 aagatcaatt accgtttgat ttatccggtg gagaaaaaca aagattattg gtttctatag
     4921 cttcattgtc aaaaactaat ttatttctat ttgatgaacc tacaagtggg ttggattata
     4981 tcaatatgga aaggattgct gaccttatta aagacttaaa agaaaagggt gcagtagtta
     5041 tagccactca tgatccggaa tttctttata aaacatgcaa tagaattatt tatttaaaaa
     5101 atggtggaat aaaaaaagat ataaaactta gagtagaaga ttcaactttg atagaacaga
     5161 tttttaatga cataacgaaa tagaattgag gagaatatat atgaaaacaa aagattatat
     5221 ttttattggt ttagctacag ttatttccct agtaatttac tttttttcaa taatggttag
     5281 tagtattggt ggggcgtttg gtcacagcat atccccaggg atttttggat tattatctgg
     5341 aatcatattt gtttatatta gctataacta ccctagaaaa ggaattttta ctatttacac
     5401 aattgtttta ttgttatttt ttacgttaat gggcggggcg tacttacctt ggtttatcag
     5461 ttcgattagt atggcgatct tagctgatat tattctatct gtatttggat atgatcgagc
     5521 aattcctcaa gttgtgtctt gggttctaat gcaactaggc agtgctgccg gacagtggat
     5581 tcccatatgg ttctttacag atcgttttcg tcaagactgg atagatagag gacaatctgc
     5641 tgcaacaatg gatgcaatga tccactacgc ggtgggtata tggggaatta tttcagtgtt
     5701 agttgtagca agtttatcta tgattggtgt attgattgga agaaaagtct taaaaaaata
     5761 caaaaaatag aacgtagttt accttctatc tgtttgtaca tctctaattt acgctattac
     5821 ggaaagcatt aacagttgta aacgaataag agaagaaatt gaatgcgggg gaggaaaaaa
     5881 tgaaagtata caaaaaatta tttagttatg tccctaaaat gaaatactac ggatggttag
     5941 ccactttatt ttctgatttt tctgtcgtat taacagtcta tggatattac agtatttaca
     6001 aatttcttca gtctctaatt attgtaggag atgaatattt agctaagagt tatgcggttc
     6061 aaactgttgc ttggttaact ttaggagctt tattttatat tttttctggc ttattttctc
     6121 atatccttgg gtttcgctta gagactaatt tgagaaaaaa gggaattagc ggtttaacag
     6181 aagcaagttt tcgttttttt gatttaaatt cttcgggata tattcgaaag acaattgatg
     6241 acaacgcggc taaaacacat atggcaattg ctcacttgat tccagatagt gctcaagcca
     6301 tagtaacacc tgttttatca gttgccttag gctttttcat taactttaaa attggattgg
     6361 ttctaatcgc catgttagta attggtgtat tcttgttaaa gaaaatgaca gagaatacaa
     6421 attttattca aaaatatcaa gaatcgttag atgtgttaag ctctgaaacg gtagaatata
     6481 tccgcggaat tcaagttata aagatatttg gtgctaaagt aacatcattt aaagccttga
     6541 ataaagcaat taacgattat gctaagtttg catataagta ttctttgagt gggaaaacac
     6601 cttttgttct ttttcaatgg ctattttttg gcatagtttg cattttgata gttcctataa
     6661 ccttttttat aacttctctt accactccca agatcttagc tgttgacttg ttgatgttgt
     6721 tttttttaag tggaattatt tttgtttctt tcatgagaat aatgtatgta agtatgcact
     6781 tgtttgaagc aagatatgca gtcgaaacac tagactccct ttatttagaa atgaagcaag
     6841 accaactaaa atatgggaac gagacacaga ttaaaaattg tgacattgca tttgaaaatg
     6901 tcagcttttc atacaaagaa gagtgtgttt tagaaaattt caacttagtt ttagaacaaa
     6961 aaagaattta tgcattagta ggaaaatcag gaagcggaaa gagtacgata gctaaactaa
     7021 tttcaggttt ctacaatgtg gataagggac agattaaaat tggtggtaag cctttaaatc
     7081 actattcaaa agacacaatt attaacacaa ttgcttttgt ctttcaagat acgaaactat
     7141 tcaatcagag tatttacgat aacgtttcta tagcaaatcc tcaagcgcca gcaagtaaag
     7201 tatttgacgc gctaagatta gccggttgcg aatcgatttt agaaaaattt cccgaaagag
     7261 agcatacctt aattggtagt aaaggagttt atctgtcagg aggagaaaaa caacgtatag
     7321 ctattgccag agcaatttta aaagatgcaa agattgttat tatggatgaa gccagtgcat
     7381 ctattgatcc agataatgag tatgaactac aaaaggcttt tcaatatttg atgaaagaaa
     7441 aaacagttat tatgatagct catcgattat ccagcattaa atctgtagat gaaattcttg
     7501 tcttgtcaga aggaaaaata gtagaacgtg gaaatcataa tgaattaatg gctaaacatc
     7561 gagtgtataa acaattggtc actaattatg agaatgcaaa tgattggagg cttgacaatg
     7621 aaaaattttt ataaaaaaaa atttgcttta actgatcagg gcgcagaagc tttaactaaa
     7681 gcttctattt ctagtttttt tgtatactgc attaatatgg taccagcatt cattataatg
     7741 atgctgatag acgaattagt tttagaaaat gcaaagcccc gttggcttta ttttgcagta
     7801 tcgtttgtta ctttgctttt catgtattgg ttgttagata gggagtatga aaacttatat
     7861 aatagtactt ataaagaaag tgcgcattta agagtgcaaa ttgcagacga tttgtcaaat
     7921 ttaccattat cctatttttc aaaacataat ttatcagatt tatctcaaac tatcatgtct
     7981 gacgttgaag gtattgagca tgcgatgagt catgcaatac ctaaagccgg cggtatggct
     8041 ctgtttttcc cttttatttc agtgatgctt ttggttggta atgtcaaaat gggattagct
     8101 gttattttgc caacgttatt tagttttgtc ttaatcttgt tatcaaagaa atcccaaacg
     8161 aaagccaata ctaaatatta cgatactttg agagaaaact cggaagaatt tcaagaaact
     8221 attgaattgc agcaagagat taatagcttt aatctatcta aaaaagttca agacagactt
     8281 ttcaaaaaaa tggaagagag tgaaaggatt catttaaagg tagaattaag tactttttca
     8341 gtcatggcct tatcctctat tttctcatat gttagtttag cagtagtcat tctagtaggt
     8401 gttcacttac tgttaacggg tgaagtgact atactctacg tcgttggtta cttactagcc
     8461 gcaataaaaa taaaggattc cttcgattct atgaaagaag cagtgcttga aatattttat
     8521 ttagctccta aaatacagcg aattagagct atgaaggaaa ccagtatcca agagggatca
     8581 gatagtcctc tgaaatcttt tgacattgag ttgcgagatg tctctttctc atatgataac
     8641 aataccccaa ttttagatca tatctctttt acggctaaac aaggagaagt gactgcgtta
     8701 gtaggtgcta gtggttccgg gaaaactagt atcttgaaat tagtgtctag actgtatgat
     8761 tatgatgaag gctgtatttt aattgatggg tatgatatta aacgtgtatc tccagcttct
     8821 ttgtttagca aaatcgctat tgtttttcaa gaggtaactt tgtttaatac aagtattttg
     8881 gaaaatatac gtattggaaa tagtcaagcg tcagatgagg aagtgaaaaa agcagctcgt
     8941 ttagctaact gcgaagactt tattgaaaaa ctacctgacg gttatcatac attggtcgga
     9001 gaaaacggaa gttcactttc tggaggagag cgacaacgcc tatccatagc acgggctttt
     9061 ttgaaaaatg cgccaatttt aattttagat gaaattactg ccagtttaga tgcggaaaat
     9121 gaaaaacgta ttcaggaaag tttaaatcgt ttaatacaag ataagacagt actaattata
     9181 tcgcatcgct tgaagtctat tgaaaaggta aataaaattg tagtgatgga tcaaggaaaa
     9241 ctagttgatc aaggtactca taatgagttg tatcgaaggt cagaaatata caaaaatctc
     9301 ataaagaaaa ctaaactatc tgagaaattc gtctatgaaa aagaagctca atcacgatga
     9361 tgaaataggc tttaaattaa cctacaattt ttgggatata gttataattc tttttcaaaa
     9421 agaataattt tattaaacag catctaattt tgaatacacg aaagaatcag tatgattgaa
     9481 ttagttcact taatgtctat tcttataata taaggaataa tcaaagtttt aaaaaattgg
     9541 cgataaacca gttaaacata aaagattgaa taaaaagtta tagtttcttt catattgccg
     9601 ttttaagtag aggaaaagct acttaaaacg gtatttgtgt ttgattggac taataaaagt
     9661 gaattcttat ttttcagagc ctaaactgca tattctttta aatgatttga ttatctctat
     9721 gtaccgataa attcgttttc aaatagttat ctattcatat gagttttatt tcatgttatt
     9781 tattgttgac aagagcaact cttgttggta aagtatcagt gtcaaaacgt aacgattacg
     9841 atttgaggtg tctaaatcaa aataaaagga gtataaaggt atatggcaaa aaagtcgaaa
     9901 attgctaaag caaagaaaca aatggcgatg attgaaaagt atgcagataa acgtcaggaa
     9961 ttaaaagccg caggagatcg caccgctctc gctaaattgc caagagattc aaatccgaat
    10021 cgtctgaggc ttcgtgatca gacggatggt cgtccaagag ggtatatgcg aaagttcggt
    10081 atgtcccgta ttaagtttag agaacttgcc catcaagggt tgattcctgg agtaaaaaaa
    10141 gcaagttggt aaaaggagga aatatcatgg cagtaccagc aagaaaaaca tctaaggcga
    10201 agaaacggtt aagaagaact catcaaactg tagtaaaacc agaaatttca tttgacgaag
    10261 cgaatggtga ttatagacgt agccatcatg tatctttaaa agggtactat aatggaaaga
    10321 aagtaattaa aggagcttca aaatagttta atatataact tttaggaggg aatcaaaatg
    10381 gaaattattt acccaccttt agttgaagaa ggattaaagt attatcttga aacgacccag
    10441 caatcgctag ataaatgcac tttttatcgt tcgatggtag agagaggaat tattactgaa
    10501 acgggtttac cgacccaaca ggcaattgaa aatggattag tcaaagatta ctatgaggac
    10561 caaggcttat catttgatga ttttttaaga atctatccaa tttttgaaga gtatgacgag
    10621 gagttatttc aatgtatcga tggttattgg gagatacctg ttgatatgaa agaaaattta
    10681 gtttcacaat tggaatctgg cgagttaact tttgaagatg cacaacaaat tcaagcatat
    10741 cttgaagatc gataagtatt gaaggaggaa gatttatgcg tcaaaatatt attttggaat
    10801 gtgtcgaaac tggagaacgt ctgtatctca ccagcaaaaa taaacggaat aaccctgaac
    10861 ggttagaatt aaaaaagtat tcgccaaaat tgcgcagacg ggcaattttt aaagaagtga
    10921 aatagctaag tggtaaaaag gtgacaaaat gggcatacca gttacaatcg tttctgggtt
    10981 tttaggggct ggaaaaacaa cgctaatcaa tcaagccttg caagtctcac cctaccccag
    11041 ggaagaaatt attataattg aaaatgagtt tggtgaagtt gggattgatc acaaattatt
    11101 agttcatagc gaggaacggg tgttacaact aaataatgga tgtatgtgtt gcagtcttcg
    11161 cagtgattta ttagcaatat tgatttcttt actggaaaca atagaagaac atcaacaacc
    11221 aatttcacaa atcatcattg aaactacagg tatagcagat ccccaaccaa tcattcaaac
    11281 acttttaaca gcgcctcaac taagaggaag agtatatatc gatagtttat tgactgttat
    11341 tgatagtgac agttttgaac ttattgaaag agaaccacaa gcccttaagc aacttgtcat
    11401 ggcagatcgc atttttgtgt ctagaaaaca aaacttgaat ttatctgcac taaaaaaatt
    11461 acagagagaa atcaaaagta ttaacccttt atccgatatt cgaatgttca cacatagtga
    11521 aacgattcaa aaaaaggatt tttataattt gaaaaaattt aatcatccct tagtttttga
    11581 aagtgattca tcagaaaatc actataatgg caaatactat catcaacacc atcaagtaca
    11641 tgagtttaaa tcaattctct taacttcaga tcaagacata aaaaaagatt ttttactcca
    11701 atggattgac tggctgattt taaccaacca agggagcctg tatcgtttta aaggattgat
    11761 tgctttacaa gagcaggatt ttatagttgc catgcaagag gtaaacgaac aggttaattt
    11821 tcaatacacc actcgacaaa aagaccaaac cactattatt ctaatcggaa aaatgttgga
    11881 tgaagaaagg atcaaacaga gttttgataa attactggcg gaaagcaaat aatgataagt
    11941 agtgattggg ggtaatttct aatggagaaa acggatatat ctagtgcata tcgacgactt
    12001 aaaagcccga atattaaaac tagaaaaagg gcattaaaaa ttatcaaaga acataaacga
    12061 aataaaatga agaaattagc ataattaagg aaggaaaaag aatgaagaaa atcagtgtag
    12121 gacttattgg gatagcagct ctaggattat tgggagcttg ctccagcact aatgatgcaa
    12181 aagtatcgaa tgataaagat ggaaaattag aaattgtaac aacattctat ccaatgtatg
    12241 atttcaccaa aaacatcgtc ggcgatgaag cgaacgtgga tttaatggtt ccagcgggat
    12301 cagaacctca tgactatgag ccctcagcta aggatatggc aaaagctcat gatgctgatg
    12361 tttttgtata tcataacgaa aacatggaat catgggtacc aaaagctaaa gaaagttgga
    12421 agaaagctgg gcctaatgta gtagaaggaa caaaagacat gattttattg ccaggtagtg
    12481 aagaagaaga tcatgatcac ggagaagaag atcaccatca tgaactagat cctcatacgt
    12541 gggtttcacc caaaatggca attaaggaag tttcaaatat caaggatcag ttagttaaat
    12601 tgtatccgaa aaaagcaaaa gtatttgaga caaatgctga aaagtatttg actaaactga
    12661 aacggttgga tgctgactat accactagtc ttaaagaagc gaaacaaaaa agttttgtga
    12721 cgcaacacgc agcctttgga tatttagctt tggattatgg attgaaacaa gttcctattg
    12781 ctggactaag tcctgaagaa gagccatctt ctggtcgatt agctgaatta aaagagtatg
    12841 ttaaaaaaaa taagatcaat tatatttact ttgaaaagaa tgctaatgat aaaattgcaa
    12901 aaactttggc caacgaagct gggataaaat tggaagtact gaatcctctt gaaagtctta
    12961 caaaagaaca aatggataat ggtgaagatt atgtttcagt aatggaagac aatctaaaag
    13021 cgttagaaaa aacaactatg gttgctggtg aagaggtagt tccagaaaaa gaagcgaagg
    13081 atgaaaagac agttgctaat gggtacttta gagatgccga tgtgaaggat cgcgaattga
    13141 gtgattatac aggcgaatgg caatctgttt atccgttgtt aaaagatgga attttggatg
    13201 aagttttcga ttacaaagca aaaatcaata aagacatgac agctgccgag tacaaagatt
    13261 attatactac tggctataag acagatattg atactatcaa cattaaagac aacaccattg
    13321 attttgtagt caacggtgaa catcatcaat acacatacaa atatgttgga tacaaaattt
    13381 tgaattatga aaaaggaaac cgtggtgttc gttttaattt tgaaactgat gatgcaggtg
    13441 ctggtcgttt taaatatatt caatttagtg atcatggaat tgcaccaagt aaggcagagc
    13501 atttccatat tttctttggt ggagaaagtc aagaaaaact ctataatgaa ttgcataatt
    13561 ggcctacttt ctatccagct tcattgtcta aacatgaaat tgctcaagaa atgatggctc
    13621 attaaaattc aatttttgga ggaaatacat ggtaagaaaa gtattattgt ctatggattc
    13681 caagaatatt gatgcttatc ggcgttatcg atttgcaaag caaatgagat taaatgggag
    13741 tacattagct gatattgctg caactttaca tgttagtatt gacacagttc atagagtatt
    13801 aaaacgggat cctgattgtt gttttatcaa ggtcaatact ggaagaagta gacgtttagc
    13861 aaaacggcat aatagcttgg ccaattaatt gataatacca gagtagatca tttttccctt
    13921 atttggattt gatctgcttt ttattatgtc ttgaattgtc aaatcaagcg caacacttta
    13981 tcaaagaaga cttcataagg tgttctccaa tctaaacact ttctaggtct gttattcagt
    14041 ttttcaatca tctgatttat cgttgagtta tctaccgtag ctatctcttt cgattttggc
    14101 aagtattctc gaatgagtct attcgtattt taatttgttc attgttgcca agggcatgag
    14161 gatctggaaa ataaaagggc atattattca atgcttctgt aactgcgaaa tgattggaga
    14221 attcttttcc tctatctgga gtgatcgttt tgaccgcctc atttggaata ctgcttaaaa
    14281 gttcaatcat tttctcgctc acataagcgg ctttctttct ggggaccttc tttcctgcta
    14341 aaaggaagca tgattttctg tctgtcaaag tcactaaaca agtaccacca gttttgccag
    14401 ctacaatatc ggctttccaa tgaccaaaat cacttctatc atctgcggat tttggacggc
    14461 catggatcga atgagtaagg caaatctttc cacgagactc gacatgattt tttgtatgtc
    14521 ttgtttttcc tcgatggtgc aatgaacgga tcaggccttt attgccgtgt gagaggggtt
    14581 ctgtatcgaa aagatcattg caaattgcac gttagatcgt gataaaacta attgaaaagt
    14641 ccatatgttc atgcttcaaa cgattcgaga tttcctctgg cgaccactga aaatcgacaa
    14701 ataaatgacg aacaattgac caaactcacg gatcatttag aatgtgataa cgtccgcatt
    14761 tttttcttcg ataagcataa tttttttccg ctttggaagg tgaatagttt ttttcttgtt
    14821 tcttctcagt tcatgtaaaa tagtaaacgg gctatgctga atgtcgttgc caattatact
    14881 aatagaaaat ccttcttcgt gaagcagaaa gattctttct cgttcgagta tagtaagatg
    14941 acgatactgg ctcataatta ttttccttct aggagtgttc tcgacaaact tatactagtt
    15001 ggatatcgat tatgactcat ttttatgtgt tgcacttaaa gtgtaaattc aaggtataga
    15061 aagaggttcc ctatgaaaaa aatacctatt acaatcttaa ctggctatct tggttcagga
    15121 aaaacgatac ttctaaatca tattctgtac ggtgatcacg gaaaggaaat tgctgtcatt
    15181 gtaaatgaca taggggaagt aaatgttgat ggggtattag tcgacaagaa aggttttaaa
    15241 agaactggag aaaaacttgt ttcgatgccg aatggatgca tttgttgtac attacgcgaa
    15301 gatttgattg ttgaactaga tcaattagtg caattttctg acttgaatca aattgttatt
    15361 gaagcttcag gaatcagcaa accaattcca attattcaag caattatatt agctaaaaac
    15421 cctttagaca ttgatttgac ccaacgatta gagattggtg ccattattat agtagtggat
    15481 gtaaaacgtt tttgggataa tttcgaaacg ggtgaaaaga ttcaggaaag aaaagctgaa
    15541 ggtaatgtag ttgaagaaga acaggatatt cgtggcttgt taattgatca attcgagtgt
    15601 tgtaacatat tacttttaaa taatagtgac ttagtgtcaa ccaagacgat ttacaaaatt
    15661 aacggtctaa ttgctaagtt acagtccaat gccaaaataa ttaggacaat taaaggtgaa
    15721 gtagacttat cgaaaattct aaatacaaat ctttttaata tagatgagac ttcctattca
    15781 gtgggctggt tcaaagagtt agagcttggc tatcaaaatc atattcctga aacagaagaa
    15841 tatggtatct caagttttat ctatcgaaat cggttactcc ttgacgcaca aaaatttgcc
    15901 catcttacgg ataaaaattt tcctggcaat attacaagag caaaagggtt tctttggttt
    15961 gcccaacata gtgatttttc gacgatcttt gaaacatcgg gtagctataa aagtattgaa
    16021 tcattaaatt attgggtagc tagtttacct aaaattgagt gtcaaatgat tatacaaaaa
    16081 aatcccgaat tgaaggaagc ctggcatccg ttgtttggtg aacgcattaa taaactagtt
    16141 tttattggta tgaagatgga tcaacaatgt attaaggaac aacttgaggg ttgtttaact
    16201 gattctctta atgcagataa tttccgaaaa atttcaccat ttccatggaa aaagtctaat
    16261 atgtttagcc agatatcgtt aatgaaattt ttaagaaaag ctggtgtcaa gataggcgat
    16321 gtcataatta ttggcatttt gattattacc tcttttattc ccttatttgt attctctata
    16381 gaaaaggaga atgaaacaac tgaagatgct atcaaatatg ccatcgttcg aattgatggc
    16441 aaggaaatgg atcgcttcga tttggataag atcaatcata aactcgtgaa ttatcatcct
    16501 gcgaagggac aatataatat tgttgagatt aaagatggaa gaattcgagt taaagaagat
    16561 aatagtcctg atcaaatcgc ggttagaact ggatggatct caaaacccgg tcaaacgagt
    16621 atttgtttac cccataagtt agttattagt attgagaaaa aagaaagcac agattactac
    16681 atttactaat ctggaaatag atgaggaggt ttttaataag aaaaagatat tattattaat
    16741 aatagcaggg gctttattaa gtgtgttaag cgcttgtgga caagaaaaag aagcggtgac
    16801 aacaggcaca agtatcttta acgggacctg caatggttta gttaacagtc ggttagatta
    16861 cttattttgg ctcttcgtca atgagtgttg gtgaagaaat tcaatagaat aatcgagata
    16921 ctcacacggc tagacagcta tcttgtctag ccgtgttgtt gttctggctt tagtcagttg
    16981 ggtagtattc ttagttttct taaaatattt tcctcgatat aaaaagattc gttctcggta
    17041 gttttgaaag tttctatagc cataggcaat tcgttttagt actttgatat ggttattcaa
    17101 acattctata gggccgttgg aatagggaac gcgcaacgct cgtttgattt ctgtttggta
    17161 tttcttgaag gtcgtgaaca ctggttggta gtgctctggc aactccttgt agtcttcttt
    17221 taggagcgcg acgaattcag gaacatcttg tcttctgata acggaaagaa aatcctggta
    17281 gacttcgtag cctcgcttta aggaatcatc ataagataat agccgatcga ctatctctgc
    17341 ttctgtcaga tgatctcgaa atgacggacg ccagtagcga tgctgacctt tcaattccca
    17401 cgcattcttt tgaagtagtt tccagtattt ctttaagtgc ttcgaccgac gatccccttt
    17461 tttaaaggtc ttcattactt gaattcggtg gttggtaaaa gcccgaccaa tgtgttggct
    17521 aatatgaaag cgatcggcga cgattcgggc attcggaaaa cactctttca ccaatgtgcg
    17581 atagggtgta tagaaatctg aaaccactag acgcacttgt tcacggactt ttatagggta
    17641 gcgcaagaaa tagtcgcgta aaggattgag ttgccgattt tccacaatat caatcagttg
    17701 atgggtcttg ccgtccatca tgacaaagct catggctccc gagacatttt tcactgattt
    17761 gaattcatcg aaacacacca cttctggtaa cagctggctc aaagaaatgg ttttaggccg
    17821 aaggctgcga agtattcgaa tgacagtggt cggagaaatg tgcttcatac gtgcgatcaa
    17881 agacatagaa agaggttcgc ttaatagctc aagaatggct tgtttgactc tgcgagcaat
    17941 ggagcagcga cgatcactaa ctgaatcttc tgctaaaaaa gtctttccac agtgtttaca
    18001 tttgaagcgc tgtttgttaa tccgcagaat ggtcttgtag ttactgacat cattcaataa
    18061 gatggatact tttttccagc cctatttaat gatcgtttgt tcattttgat agtggcgatg
    18121 aaagcattcc tccggttgat aggtcaatgt gccatcaaaa gcaaaacatg tttcgtcatt
    18181 gatgcgctct ttgcgaaagg catcctcatg aaaggtaaga tttaggtcta gaatatctag
    18241 taactctttg gtaaactctg aataggacat cttgaaacac tactttgaat ggtttttgtc
    18301 gactttattc taaaggattt taaggtgtct gtttgcgttt attagaaaaa agaaaaagta
    18361 ttggcaacag aaggcgtcac caacactaga tattatagat cccttatttt cttcgcttca
    18421 aattgtcaag gagtcatcat aaattttgta tggattcttt tgtttgggta gtagtcttct
    18481 aaataatctt ggattaacac cttcatctct attttacttt tatatttgtt ggagtcgatt
    18541 aattctcatt tgattgatcg atgaaacgct tcaattactg cattgtcaac aggagtccca
    18601 gtttggctca ctgaatgtgt gatgtggtgg tcgttcaaca gctcttgata aataaaagac
    18661 cgatgctggc tacctctatc ggaatgaatt accgtaggca attctcctta ataaatttgt
    18721 aatggacgga cgacaatctc tttttttatg tgtgaatcta ccatatagta acgtagaata
    18781 cgagttgcta agtcaatata ggtggacaaa tagaggcgac cgtcattaca tggaatgtaa
    18841 gtaatatcca tcacccaaac agcatcaatt tggttctgtt caaattatcg attcaacatt
    18901 tttttaccat ttctttgatt gttttttctc taccatgaga agatttgcgt cgatgaaatc
    18961 ctcttgtgca taaattcatt tcacgcataa gaacagctac aacacgttta ttgatttcga
    19021 ttccttcatc gtaaagtttt tgagtgatcc ctggagatcc gtatcgatct ttgtgttcgt
    19081 agaacactcg tcttcctctt ttagtcgttt attttcctgt tcaagaatgt agaaatctgc
    19141 tttatcaggt aatctttttc cttgtccagc aaaagcattt ttcccgtatc gacgatattc
    19201 tgaaacccat cgggaaattg ttggacgaga gatattgtat tcttcagcaa ttttcttggt
    19261 agttactttt ttctcaagga tatcctgtga aatctttagt ttaaatttac gatcatatgt
    19321 ttttctcaat agagttcatt ccttccggta acgtaactga tagtcaagaa aagtgtatca
    19381 tagcccaact tagtatcagg gtttgtcaac taaactgtgg aagttgatag ataagagttt
    19441 ttaacaacca aaattctctt gactattttt gaaatcagac aaattttgat tggacacata
    19501 gttgaataaa tctaccgtcg ttacggaagg taaatcgcat gcttttcaat tctagaggag
    19561 aagtcctcgt tgaagtacca tagcccagtt ctggattcga cctcctgccc acttcatacg
    19621 taaataaagt aattttagga gtgagactgt gacaaaagtt atttttaagc taaaaacgaa
    19681 ttaaaaaacg ttgataatta aaatcattcg ttttagattc tatgaatcat tatagaacgc
    19741 tgtaaaatcg atactttata attataaaga agatagtttc aaatttattg ttcgaaattt
    19801 gaaactatct ttttacttat gtcacagact cccttagttg agttattctt taatttcgaa
    19861 tttcgagata gctagatata ttgcaagcat acattcttga taacaatctt gatcatattt
    19921 tccagttctc caggattgct tatgaatcaa agagctaaat cttttgagaa ttgcctcaac
    19981 agcttcttca tttccagcct ttgctaaaat gaaatcttct tttaaagaat tcataaatct
    20041 accttcttcc catggactta taatctattt ctttgggaag gaggagaacg agcaaagaag
    20101 catacaaaat tagttattat gcagatatta aaccagcatt ttttgaattt ttttgtaaag
    20161 tcgatgtttt aaatttgtcg caccctgtct tgtaatcccc agaacctttc caatttcttt
    20221 atcagtttta tcaaagataa atttttcgat aagaaaaatt tgttcaggtt ctttcaacaa
    20281 aggaaggatt tttgctaatt ttatatcttc aacaaggaga gtcacattta aaacattaat
    20341 cggttgttta aattttatag tatctttagt aaacaaatat ggtgggagtt gatcaagttg
    20401 ttcatgtttt tgaatttctt cttgtttttt ataataagta ttagcggtgt tcaaaatgac
    20461 cttttcaaag aatcgaatca actgggcatt tacgcgttcg tcgttatctg acatattgca
    20521 cacctcctcc attaagattt aaagggaaaa gaggcaaaaa acacgaaaag aagctaatgc
    20581 aattatgctg cgctgcgaat aacttctata agctcacatg cattgatagg actgctgatg
    20641 tttattttca aaaatgtttt tttagttgat aatggatagt tatctttata cttagaaaag
    20701 aaaattcata tatcttctta aatatcaaac atgtccttat ggctaagaaa atgtcttgag
    20761 ctttttacgt ataataaatc ttttctaaaa cctccttttg gataatattc ttattcgtgt
    20821 atagattgta ttttttattt cttccccctt cataattaac aactagaaaa gagttcgaat
    20881 agacacgtat ttgaacgaaa atttttattg gattcccaaa ttggaatatt tagaaacgaa
    20941 aaattcctat tatctgtata gtgcttagat aataacggat cataataatt attgtctttg
    21001 aactagatat atgtaaatag tattcatcat gatgaaaaat gatgagttct cggtgataaa
    21061 atgtactttt tacggtggaa tatacatgaa agcgataagt ggatatttta taatgaagta
    21121 agttagctta ttttgacaga ggaatagtat tttagataac gtataaaata ctatttaatg
    21181 atgtagaaag gaaagagaga aacaaaagtg ttttcagata aagaagtctt attaaagtct
    21241 cttcatgttt gtttaaagtt acctatcgtg gtttttaatt ccgaattcag tattataaaa
    21301 gagtatcgct cagatagaac tacttatttt ttttatgatt ataaaaagtt actaactgat
    21361 aatattaaaa aaactaaaga tttccatttc tttactggtg attttaatga gatgtttctt
    21421 ctatacatgt ttaaaaccag atattactta tttggtccat ttagagcaaa taatattgat
    21481 aaagtttttt ttaaactaaa aatgaacaat ttgaatgttg caatggctga tagagaacga
    21541 ctctataatt cattgcaaaa tttgactttg tattctttag gagacattcg agatattctg
    21601 attttagttc attatttttt tactggaaaa atagaagatc tattccatga accgttaatt
    21661 gaatatacag aaaatctaag taaaactatc gagcaaatca aaatagataa tctgttatca
    21721 caaaattacg atccagaaat atatctgttt ctttatgaaa ataaaatact ggaatatgtt
    21781 aaaaatggag atattcgaaa tttagaaaac atggttttta atctgagtaa tggaataatt
    21841 ccaagtgtta gtggagatac gattcggtct gaaaaaaatt attctatcat tgtttttgaa
    21901 aagttagcac aaacgtctat aacattagga atggatataa tagaagcgta tcaaagtaga
    21961 gatgctttga tacaagaaaa cgaattagct gtatcgttac ctgaggtctt aaaagtgagg
    22021 gattctggga ttgtttatta tactaaggaa atcggaaaaa ctaagataga gcatctttct
    22081 cccttaattt cttctgtcgt tcaattcatc ggcttaaata tctataaaag aattactgta
    22141 aaggaaatag ctaattattt ttctgtaagt gaaactaaat taagagaaag ctttaagaat
    22201 gaaatgcata ttacgattta taattatatc tctaagcgaa aaatttctac ggctaaaata
    22261 atgttgaaat caaaccatac tatcagtgaa gtttctttag gtttaggatt ttcagattct
    22321 tcacactttt cgagagtatt caaaaagtac gcaggtgtat ctcctaagca atatcaatta
    22381 ggtttagtgg acaatttcaa caacattagc tgagaggttt tattttatta tgagactata
    22441 tcatttacgt agtttggagg agttgaggaa attggatttt aacaaaaaat ttttttggga
    22501 aatttctgat ttgagttgtt tcgtagaatc tgagcgtcta agtaatggta ataatagtgt
    22561 gttaaatgaa tatgacaaag tagtaattaa taaagtaaaa agtttatgtg aagaagctag
    22621 agaatctatc agtcatatta atggtagcaa ttttaaacaa acattattta atctgattaa
    22681 gctagatgct aaaatatcaa gttatttatt ctttttgata catgatgaat ttatggatta
    22741 tcaaaaattg gatcagttaa ttgaaagaga aagctgggaa gattattacg tgggtctaac
    22801 tttttcagaa aagttaaaca actacaagtt aatagattat aagtatttga gtgaaagcaa
    22861 ttaattattc atgtagagta ctagacactt taaatatgga caattcaatt ataaagaaaa
    22921 agaatcaata atttaatgag gctgtgacaa atgtcatttt ttgtttcgct aaaaacgagt
    22981 gaaaaaatgt tgataactcc aatcattcgt ttaagattct aggaatcatt cagaaatgct
    23041 gtgaaaccga tactttataa ttataaagaa ggtgatttca aattccgaag aaggaatttg
    23101 aagtcacctt tttacttatg tcacagtctc attcagtaat gcgggataag gctccttatt
    23161 ccgttatttg aatactctga agtttaatct aagaaagggt aatattttga aaacatgctt
    23221 catcgcatag aaatgaactt aatttcagaa agaatacata catatctttt tatatgtttt
    23281 cagctgctga atggttaaaa agcacaaata tccgaaaaaa acatgaagaa atgtactttt
    23341 tttgttgtaa tgttcatgaa attctctaag taaattagtt aacataaggt tagtaagatt
    23401 cctattctgt gaataatacg tatcagattt atcttttatt cttactagga aagtaattat
    23461 taagggagtt gatttgaata atggttagca agaataataa gagagtattt ctagaaaaaa
    23521 caaagaaacg agtattgaag tacagtatca aaaaattaag tgttggggtt gcatctgttt
    23581 tgattggtgt tggtcttgtc ttgggaacaa ctgaactagt taaagcacaa gatgaaattt
    23641 ctccaagcag cccacttgaa acagcgataa gctccgtaca agtaggtgac aaagtagctt
    23701 cggggaatac ttttcaggag aatcctggtt atacgaaaaa ttataacttt tcggatttac
    23761 aatttagtcc tcaagaacta actggagaca cactaaaagg caatacaatt ggatttgaag
    23821 tttacggaaa acataatatt gcagcatcaa ctaaaaactg ggaaatccgt cttcaattag
    23881 atgaacgatt agctaaatat gtagaaaaaa ttcaggtcga tccaaagaaa ggaattggat
    23941 cttctagacg gacctttgta agaattaatg attcgctggg tagacctaca aatatttgga
    24001 aggtcaatta tattcgtgca agtgatggat tatttgctgg ggcagaaaca accgatacgc
    24061 aaaccgctcc taatggggta attacgtttg aaaagagcct agatgaaatt tttaaagaga
    24121 taggcataga caatctcaag accgatcgtt taatgtatcg aatctacttg gtaagtcatc
    24181 aagacgatga taaaattgta ccgggtattg atagtacggg ctacttttta acagattcag
    24241 atgatttcta taatagctta gatgtatctg aaaataatcc tgaccagttt aaacatggat
    24301 cagtaagtgc aaaatatgag aaacctaata ctcaaacaaa agatggttca ggatccacag
    24361 gtgctaatgg agctataatc ttagatcata agttaacgaa aaattataat ttctcatatt
    24421 catcttccgc aaagggcacg ccttggtatg ctaattacaa aattgatgaa cgattagttc
    24481 catatgtagc gggtatacag atgcacatgg ttcaggctga caaagtaaca tatgatgttt
    24541 cgtttgaatc cggaacaaaa gtagctgatt tagcaatcga gcgacgggaa ggtcatgaaa
    24601 attatggcat aggttcaata actaataatg atttaactaa acttatcgat tttgctaatg
    24661 caagtccacg tccagtcgtt attcgatatg ttttacaatt gactaagcca ttagatgaaa
    24721 tcttagaaga tatgaaagca acagcacaag ttgaagaaaa taaaccattt ggtgaagatt
    24781 tcatctttga ttcttggttg tcggatacga ataaaaaatt aatccagaac acttatggaa
    24841 caggttatta ttatttgcaa gatattgatg gtgatggaaa ccctgacgat aaagaagaga
    24901 gcggagacac gaatccatat atcgggaaac ctgaattaga agaagtatat gatgttgaca
    24961 caacagttaa ggggaaagta ttcatccacg agttagcggg aacaggtcac aaagcccaac
    25021 ttgttgataa agaaggtact gtattagcag aaaaaactat cgctccaaat gaaaaagatg
    25081 gggctccaat ttcagatact gtagaatttg aatttacggg tgtagattca agtaaattaa
    25141 tcgcgaaaga tgaattaaaa atccaaatcg tttctccagg ttttgataaa ccagaagaag
    25201 gttcaaccgt tattaaggaa tcaccaaaag cggttgataa acaaaccgtg gtagttggat
    25261 ttaaaccaga tgctaaagaa tcaattcgga ataataaaaa cttacctgaa gatgcagagt
    25321 attcatggaa aacagagcct gatacttcta acgttactga tagtacgaaa ggtattgtaa
    25381 ctgttaagat cggaaatcga actttcgacg tggatgtaga gtttgctgta aaagcttctc
    25441 aagctatgga aaatgatgca acatacgtac ctataacaac aactccagaa acgacagttc
    25501 aaagtggaaa acctacattt gataaaccag atgttccttt agctaaagat gccttttcaa
    25561 tttcagatgt ctataataag gacttcggta atgcaagtgt tgatgcaaac actggtattg
    25621 ttacattcac tccagctaaa ggtgtaggag aatcggagcc gattactgga acaattccta
    25681 ttaaaattgt ttaccaagat ggttctgtag gcacgaccga tttagcagta actgtaagta
    25741 aagatattta tgaaaatcca ggagaaaaca ttcctgcagg ctaccacaaa gtaaccttca
    25801 ccgcagg
//
LOCUS       DASHWW010000033        23801 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.033, whole genome shotgun sequence.
ACCESSION   DASHWW010000033 DASHWW010000000
VERSION     DASHWW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.033"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1248)
                     /locus_tag="U2R64_001573"
     CDS             complement(<1..1248)
                     /locus_tag="U2R64_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HEM8918395.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYL"
     gene            1521..3992
                     /locus_tag="U2R64_001574"
     CDS             1521..3992
                     /locus_tag="U2R64_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8918396.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(4095..5831)
                     /locus_tag="U2R64_001575"
     CDS             complement(4095..5831)
                     /locus_tag="U2R64_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEM8918397.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5828..6532)
                     /locus_tag="U2R64_001576"
     CDS             complement(5828..6532)
                     /locus_tag="U2R64_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8918398.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDLHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            6663..7166
                     /locus_tag="U2R64_001577"
     CDS             6663..7166
                     /locus_tag="U2R64_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HEM8918399.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7126..7464
                     /locus_tag="U2R64_001578"
     CDS             7126..7464
                     /locus_tag="U2R64_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEM8918400.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7485..8903
                     /gene="ffh"
                     /locus_tag="U2R64_001579"
     CDS             7485..8903
                     /gene="ffh"
                     /locus_tag="U2R64_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEM8918401.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9015..9593
                     /locus_tag="U2R64_001580"
     CDS             9015..9593
                     /locus_tag="U2R64_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEM8918402.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            9597..10118
                     /locus_tag="U2R64_001581"
     CDS             9597..10118
                     /locus_tag="U2R64_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8918403.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10197..10751)
                     /locus_tag="U2R64_001582"
     CDS             complement(10197..10751)
                     /locus_tag="U2R64_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEM8918404.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLVFSNKLTE"
     gene            11004..11279
                     /gene="rpsP"
                     /locus_tag="U2R64_001583"
     CDS             11004..11279
                     /gene="rpsP"
                     /locus_tag="U2R64_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEM8918405.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11291..11542
                     /locus_tag="U2R64_001584"
     CDS             11291..11542
                     /locus_tag="U2R64_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEM8918406.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            11667..12458
                     /locus_tag="U2R64_001585"
     CDS             11667..12458
                     /locus_tag="U2R64_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918407.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            12628..13149
                     /gene="rimM"
                     /locus_tag="U2R64_001586"
     CDS             12628..13149
                     /gene="rimM"
                     /locus_tag="U2R64_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEM8918408.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13139..13900
                     /gene="trmD"
                     /locus_tag="U2R64_001587"
     CDS             13139..13900
                     /gene="trmD"
                     /locus_tag="U2R64_001587"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEM8918409.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            14036..14383
                     /gene="rplS"
                     /locus_tag="U2R64_001588"
     CDS             14036..14383
                     /gene="rplS"
                     /locus_tag="U2R64_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEM8918410.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14756..15418
                     /locus_tag="U2R64_001589"
     CDS             14756..15418
                     /locus_tag="U2R64_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918411.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            15497..18724
                     /gene="fss3"
                     /locus_tag="U2R64_001590"
     CDS             15497..18724
                     /gene="fss3"
                     /locus_tag="U2R64_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEM8918412.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18838..19152
                     /locus_tag="U2R64_001591"
     CDS             18838..19152
                     /locus_tag="U2R64_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8918413.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            19165..19539
                     /locus_tag="U2R64_001592"
     CDS             19165..19539
                     /locus_tag="U2R64_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8918414.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            19549..19893
                     /locus_tag="U2R64_001593"
     CDS             19549..19893
                     /locus_tag="U2R64_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEM8918415.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19964..21109
                     /locus_tag="U2R64_001594"
     CDS             19964..21109
                     /locus_tag="U2R64_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEM8918416.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            21824..23683
                     /gene="ltrA"
                     /locus_tag="U2R64_001595"
     CDS             21824..23683
                     /gene="ltrA"
                     /locus_tag="U2R64_001595"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8918417.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
BASE COUNT         8093 a         4211 c         4936 g         6561 t
ORIGIN      
        1 taaatagatc cgtgcccgaa agttataaaa gttgcgataa ccaaacgcaa ttcgtttaat
       61 cagcttgatc ttgttattca gcccctcagt gacgccgttt gagtgggaca ccttaaaggc
      121 atttgaaata cccgattggt agcgatggaa gatcgtgaat ttctttttaa acgactgagg
      181 taacgtagat gaaattgttt taagggtttc ttgaaagcct tccgtacctc gtttaacgaa
      241 ataatagcgt aataattgac aaaaatgata cgcagttcgc aattcttcgt tgtagcttaa
      301 cagctcatca acgatttctg tttgactaat tggtcgttta aacagtcgat gataatgccg
      361 tttgagtggc tccaatgtcg tggaatcttt gagtaagagt ttccaatatc gcttgagccg
      421 acggtacttc ttctgatttt cagagtgtga ggttcgaaaa cgattcatga tctggacacg
      481 taattgattg aagctgcgat tgatgtgttg gacaatatga aagcggtcag ttacgatctc
      541 cgcatttgga aagactgttt taagcaactg acaatagctg gcattcatgt ccatcactag
      601 gtacttgacc tttaaacggg cctttctagg aaagcgcagg aagtattgag ttagtttgta
      661 aagtctgcga tcttcaagga tcgtaaatag ctgattggtt gtcccatcaa cacaaataaa
      721 actcatggaa ccagaaacag aattcattga tttgaactca tccatacaca acaccgtcgg
      781 aaggaagttc atacgtggct ggtaatgctt cgttgcttca cgcaagatcc gtgtcaccgt
      841 cccatccgag acgaagtact tcttagcgat tagtttacgt gattgatttt cgtacagttc
      901 catgagaatc acctgcttca gttcctttgt tagttgatga tgttcatcaa ctaagtccgt
      961 tttcgcagaa aaggtccttc cacaatcatg gcagagaaaa cgggtacgtt ttaattctaa
     1021 aatagttaac ttttctttga ctttcaacat ctgagtgcgt gtcgtatagg aaccgttgcg
     1081 gataatacga accgatcgac agtgttcaca ataggaagaa gagtcatcca attttccttt
     1141 aataaactgc gcttgaacgc ctttatattc tttttcaatc agccattctt catcaaaaaa
     1201 taaatgttta tctgttaatc cgagtaattt tctagtatga ttatccattg agagactcct
     1261 ttggtaggat gacgttttgg tcgactaaat tttaccaaaa gtgagtctct ttttgagttg
     1321 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
     1381 tagaaccctt tttttttgct atatgacagg aatgaaaggt gtttgcaagc ttaatgtgag
     1441 gaacactttc catatctgtt ctatactgga taggagaagt ttggaaatat ccagaaaacg
     1501 aaatcaatcg aggtagccac atgaagaata aatggataaa tcgaagtaaa aaaaagaaag
     1561 taacacaaag atcatcagat aaagtcatcc gtctttttcc atcgtataaa gaaggattaa
     1621 cggcagatca agtcaaggaa cgaatagaaa aaggtgcagc aaataattca gtcgatccca
     1681 cattcaaaac aaatcagcaa atcgtattgg aaaacatatt tacgtatttc aatttgatct
     1741 ttcttatctt agccattttg ctttgtttag tagaatccta taagaacttg acttttttac
     1801 cagttatcat agccaataca ggaatcgcca tttttcagga aattcgatcc aaaaagatct
     1861 tggacgaact aaatgtttta aatacagcaa aagtcaatgt catacgagac gggatagaac
     1921 aaacaataga tatagaagac cttgtaatag atgacattgt tattttagag actggatatc
     1981 aaattccagc agatgcagag gtcgtggaag ggaaactgca agttaatgag gctttattga
     2041 caggcgaagc agatgaaata accaaagaaa taggtgatcc attaatgtcc ggcagtttca
     2101 ttgtttccgg aaaagcttac gcccgattag acaaagttgg agcagattcg tatatttccc
     2161 agctgacagt caaagccaag acaatgggag aaggagaaca gtcggagatg attgcttctc
     2221 ttaatcaatt gatcaaatgg attgggatca tcattattcc tatcggtatc ctgctttttt
     2281 ctcaaagtta cttttttaat ggaaacacga tcaaagaaag tgtcgttgca atggaagcag
     2341 cattgatcgg tatgatacct gaaggactgt acttgctgac gacgattgca ttagcattaa
     2401 gtgcgactaa actagcaaag caaagagttc ttttacacaa tatgaaaagc attgagacat
     2461 tggcaagggt aaatgtcctt tgtgtagata aaacaggaac gatcacagaa aataaaatgt
     2521 ctgttcaaaa aatgatcgtc tctaaaaaac aagaaataat cagtcagtca gatcaattgg
     2581 aagcatgcat tgctgactat gcaaaagcga tggcaggaga caatgcaaca atggaagctg
     2641 ttaaagcata ttttacaaaa accactgatc aatcctatca ccatgttatt cctttttctt
     2701 ctgtccaaaa attcagcagt gtagcgttgg cagacaaggt gtatgtttta ggagcgcccg
     2761 aaatggtttt gcgcgatcaa ttgccggaat atgcggaaga gtttgtttct ttcgctgaaa
     2821 aaggctatcg cgtgttggtc tttggtgtgt acgatgggat tcttgaagaa ccagtattga
     2881 cagaagcagt cacaccatta ggctatattc tgattgctaa tcctatcaga aaagaagcaa
     2941 gagccacatt tgattacttc aaaaaacagc aagtagccat caaagtgatt tctggagata
     3001 atccgctcac cgtatccaat gtagctgtcc aagcagggat ttcacatgct gatcagtacg
     3061 ttgatgcatc taaattatca gaagaagaat atgaagcagc tgtcgaaaaa tatacagttt
     3121 ttggacgcgt caagccagaa caaaagaaaa tcttcgttca attgataaag cgtaacaata
     3181 cagtagctat gacaggtgat ggcgtgaatg atattctagc catgaaagaa gcagactgca
     3241 gtatagcgat ggcttccgga aatgaagccg ccatgcaggc ctcacaagtg gtcttacttg
     3301 attctgactt ttcacgcatg ccagaagttg ttgcagaagg acggcgcgtt gtgaacaata
     3361 ttgagcgatc agccagcttg tttttagtga agaatatttt ctcctttttg ctctcactgt
     3421 tttcagtgat ctttgctctg acctatcctt tagaaccatc acaaatcaca ttgattagtt
     3481 tgtttactat cggacttcca tctttcttgc ttgctctaga agaaaacaaa aagcgaatca
     3541 gagggaaatt catcatgaat gtgatggaaa aagctgtgcc aggtggacta acagatatga
     3601 tcgtagtcgg tgcgttggtg atctgcgggg tgactttgaa tctaaataaa acagatgttt
     3661 ctacagcatc taccatgctt ttgattgcag tagggttcct cgttctctat aaaatctgtt
     3721 caccgctgaa taaattcaga agtcagatca ttcttttctg tgctagcggt aacttttttt
     3781 cggtcatctt tttgcataag ctgttttcaa tcaccggtat ctcagctgta tcacttttgc
     3841 tgttgagcat tctatttttc tcggcagatt cgatttttag gcatttgacc acattggtag
     3901 aatatttgtt tgaacgtaaa aatgaaaaag agcaaaagcc gtttagtcgc gtagctaaaa
     3961 aatttctatc gatatttaaa cgagaaaatt gacgaaaagt atctcaaaaa agagtaaaaa
     4021 agaacaacca ctcgtgtatc tttcgaagca ggatgagtca tccaacttta aaacgcacga
     4081 gcagttgctc ttttttacat tttcggaatg gtaacggtga aagtcgaacc tgttccaaga
     4141 tgactgtcta cagtaatcgt accattaagg agttgcacgt agtcttttac aatcgctaac
     4201 cctaatccgg tcccgcctga atgtcggctt cgcgccttgt ctacgcggta aaaacgctca
     4261 aagatccgtt cctgatcctc aatgtcgata cctataccaa agtcttggac agaaaacgat
     4321 agatcatctg ttgcctgata gcggataata atctcgctgt cgctttttga atattggaca
     4381 gcattttcaa ttagattttt gataattgga taaaggatat ctgttttagt agtaaatggt
     4441 tcgttctttc caatcaatcg aatcgtcaac cgtttctttt cgatgattgg ctgataattt
     4501 tgaacgattt gctggaaata aggttctgta taaattgtct ggatctcgta agaattctcg
     4561 ccatcttttg acagctggat gatttcccga atcagtttat ctaaccggat cgcatctttt
     4621 tgcatgatct caagaaaaga agtcagagtt tgcgggtcat cttttgcacc atccagtaaa
     4681 gtctcggtaa aaccaatcag tgaagtcaca ggagttttta attcgtgaga gacgttgcca
     4741 acgaaatcct tttgtagctt ttctaaacgt cgcactttcg ttaagtcata cgccacccct
     4801 agaatctgtc cggtaccttc tgaattagta aagtagcgca aactcaagtc taatgtctgc
     4861 cgaccttctg taagggtgat ctcctgatgg atcagcggat gctcaggagt cacttgatga
     4921 atcagctgaa tgagttttgg ctcttgaatg acttctgtgt accgctgttc aggttgatag
     4981 cttaccacgt ttaaatgtag ctgcatcttt ggattaagca gtagtaaacg agaatcagca
     5041 tcatcaatca ggaatacgcc aatcatcagt tcgttcagta acgtatataa ttgctcttct
     5101 gtggtagtac acgcccgata catcttactc atttgttcgc tcaacgcatt aatcgtctga
     5161 tacaattctt cccattgatc gggtgtttgc atgattactt ccgcctgatt aggattttgc
     5221 accatttttt ttagtacggg cagcacggtt ttcaatggct ggtttttttg atagatcaga
     5281 taatagatca ttcctgcaag aacaaggaag aaagacagaa agaagaaaaa gacccaacgg
     5341 cgaaaactct cagttctcgg taaaaaaccg cttgtcggtt ctgcgatacg taaaatggct
     5401 tctaactggc cacttttttt gactggtaat gcgacatata aaagatcctc attcaaagta
     5461 gtacttttgc gcaaagcgct acctaggttc ccaccattca atacggcttt gatttcggga
     5521 cgggagtttc gctgttcatt caatgtttca ttgtttgtgt caaataagat ctttccagta
     5581 gcatccatta aagtaatccg ttcgttcgac tgatggacga attcttccaa agcagttttg
     5641 ttttgcgctg cttggaggtt ttcgacatct aattgccgga tcagcagttg tgcttttttt
     5701 gtcaggtagc tttcttgctg ttccacgatc tgctgttgaa aataatggga aatcaattgc
     5761 cagccaccaa aaaacaaact aactaaaaga ataagaaaga agagacgttc ataaattttt
     5821 ttccatttca tcgtttgggt tcctgaaact tatagccaaa tcctctaata gtcaccaagt
     5881 actttgggtg ttttggatct cgctcgattt tttctcgcaa atgactaacg tgtaaatcta
     5941 cgattcggct ttgtcctgcg aagtcaaaat tccaaatgcg gtctagcaat gtgtctcggt
     6001 cgatcacacg gtcttttcgt ttcatgaaat aaacaagtaa ttcaaattct ttcggtgtta
     6061 gttcaatcag atggtcgtct acggtcactt gataattggt caaatcagca gtgatttgtc
     6121 caatcgatag atattcaggc tcagcttcat cttttgattg cttacgaggt tcaattcgtc
     6181 tgaatattgc tttcatacgg gctaatactt cgcgaggact aaatggtttg gtcaaatagt
     6241 cgtcagcacc tatttctagg ccaatgatcc gatccacttg gtcatcttta gccgtcagca
     6301 tcaaaatcgg tgtttcattt ttttcttgac gcagccgctg agtgatctcc atgccatcca
     6361 tcgttggaag catcacatct aaaatgatga aatcaaatga ttgttctaat gctaattcta
     6421 atccttcgcc tccatctgtg gcactggtta ccttgtagcc ttctttttcc aaattgaacg
     6481 tcaagagcgt tacaatagaa ggttcatcat caacaactag tatttttttc attcaaatct
     6541 cctttaaata ggtttcattc tgtttatatt ttagcataga atcagtacaa agggctattt
     6601 tacaaaagaa ataaatggta taataggaag gcactttgct gaatagaaag gaagagcagt
     6661 caatgattgg aatcagtgca tgtttaggcg gtctggcctg tcgctatgat ggacagaaaa
     6721 aagaagtacc agaattgatg gaactagttg aaactggaga agctgtcatg gtctgtccag
     6781 aagtgatcgg cggattacca attcctagag atcccgctga aatcattggt ggaaatggat
     6841 tcgatgtgtg gaaagatcaa gcaaaagtat ggacgacaag cggcgaagat gtaacggaag
     6901 cgtacaaaaa tggcgcgatc aaagcctatc aaaaattgca ggaaaaacac attgatctag
     6961 tcatcatgaa ggaaaaaagc ccttcatgcg gaacccattc gatttatgac ggaagttttt
     7021 ccggaataaa aaaaaatggt gccggagtgg ctactgctta ttttattcag caaaaaatga
     7081 ctgtgctctc tgatgaagaa tggctgaaaa ctagaggtga gcagaatgga aatcgaaaag
     7141 accaatcgaa tgaacgcgct ctttgaattt tattcgacct tattgacaga aaaacaaatg
     7201 aactacatgg aattatatta tgcagatgat ttttcattag gtgagatcgc ggaagaatac
     7261 gaagtaagcc gacaagcagt atatgacaat atcaagcgga caagcaagat cttggaggat
     7321 tatgaaaaaa aactccatct tttttctaat tatattgttc gagaacaggt attggaaaat
     7381 atgactgcat atattacaga taagtacccg gaagataaaa aactacttga atatgtacag
     7441 caaattcaag caatcgaaga ataaataaaa ggaatgaaga aaatatggca tttgaaagct
     7501 taactgaacg tctccagcag gcgatgggaa aaataagaaa aaaaggaaaa gtatcagaag
     7561 ctgacgtaaa agaaatgatg cgggaaatcc gccttgcctt actagaagcc gatgttaact
     7621 tgcaagtagt caaagatttt actaagcgcg tacgcgaacg tgcggtaggg gcagaagtgc
     7681 tggaaagttt atcacctgca caacaaatcg taaaaatcgt tgatgaagaa ttgacgatca
     7741 cacttggttc tgaaacagca gagttaaata aatcaccaaa aataccaact gttatcatga
     7801 tggctggtct tcaaggggca ggtaaaacga cctttactgg taaattagcc aattatttaa
     7861 agaaaaatga aaatgctcgt ccgctcctaa tcgcagggga cgtatatcga ccagctgcga
     7921 tcgaccaatt gaaagtatta ggtcaacagc tagacgttcc tgtatttgat atgggaactg
     7981 aagtcagccc ggtagagatc gtccgtcaag ggatggagtt agcaaaagaa aagaaaaacg
     8041 actatgtatt gatcgatacg gcaggacgtc tgcatatcga tgaaacattg atggatgagt
     8101 tgaaacaaat caaagaattg acgcaaccaa atgagatttt gcttgttgtc gatgccatga
     8161 ctggtcaaga tgccgtcaac gtagctgata gcttcaacca gcaattaggt attacagggg
     8221 tcgtcatcac taaacttgat ggggatactc gaggcggggc agcactatcg atccgctcag
     8281 tgacaggcgc accaatcaaa ttcatcggtt ctggtgaaaa attgactgac ttagaagtat
     8341 tccacccaga tcgtatggct agccgtatcc ttggtatggg ggatatgctg acattgattg
     8401 aaaaagcgca gcaagactac gacgagaaaa aagcggaaga acttgcacag aaaatgcggg
     8461 aaaattcatt cgatttcaat gactttattg aacagcttga tcaagtgatg ggtatgggcc
     8521 cactggaaga tctaatcaaa atgatcccag gaatgaatca agtccctgga atcgaaaacg
     8581 tcaaggtaga tccaaaagat gttgaacgca aaaaagcgat ggtttattct atgacgccag
     8641 cagaaagagc aaatcctgat ctgttgaacc caagccgtcg tcgccgaatt gctgccggtt
     8701 ctggaaacag tgttgttgaa gtgaatcgaa tgatcaaaca attcaaggaa tcaagaaaaa
     8761 tgatgcagca aatgtccaaa ggggatatga acatcccagg tatggaccaa atgtttggtt
     8821 caggcgtcaa aggaaaacta ggcaaaatgg cgatgaatcg aatgatcaag aaaaataaga
     8881 agaaaaagaa aaaacggaaa taagatgaaa aaaacagctt cggtacagac tgaaaatgtc
     8941 tactgccgga gcttttctat cagcaatttt tattctttac taatacaatt actctaaacg
     9001 aagaggtggc acagatgaga tgtccgtgga gtgaacaaac agaaagtatg cggcaatatc
     9061 atgatactgt ctggggtgtt cctgaatatg atgaccaaaa gctgttccga aaattgatgc
     9121 ttgatattaa tcaagccgga ttgagctggc agacgatttt aaataaaagt gaagcattcg
     9181 atgaagcata tgatcgattc gatatcaaaa aagtcgcaaa ttatggagaa acaaaaatca
     9241 gtgaactaat ggaaaacaaa ggaattattc gtaaccgaag aaaaatcgaa gcagccgtcc
     9301 aaaacgccaa agcagtcttg aaaattcaag aagaaatcgg cagtttttca gagtatcttt
     9361 ggtcgttttc taatggaaaa atcgttgatt cttcttatca ttcacaagaa gaagtcccaa
     9421 caacaagtcc tctttcagat gaattagcaa aagatctaaa gaaaagagga tttaaattta
     9481 tcggaagcac aacaatctat gcttttttag aagctgtcgg gatcatcaat gatcaccttg
     9541 acagttgttt ccgcaaagaa gaggtcgtac gtatcggcag aaagggcgaa taaagcatgc
     9601 gaaaaatcat attttatggt gctataagtt tagatggcta tttggcaacg aaaacggatg
     9661 atcttcaatg gctttttgac actccaacag gtaagcaaac tacttatgaa gctttttatg
     9721 aaacaatcga tacgaccatc atgggcagaa aaacttatca ggaagcaaaa aaatatttgg
     9781 agaccgaagc aatttatcca gagaaaaaga atttcgtttt ttccacccac gcacaattac
     9841 aattgccaga tgctgaggtc gtaaacgaag atcctgttgc ttttctaaaa aatctacaaa
     9901 tgacagaagg aaaagatatc tgggttgtgg gtggcggtcg attgatcaaa ccgctattgg
     9961 aacatcaaat gattgatgaa tggtatatcc agattacccc tgtattatta ggggacggga
    10021 ttcctttatt ccaaaaagga acatatgaag cgcgttttga aatgctagac acgacacgat
    10081 tcggtgaatt tatcgaattg cattatgtac gaaagtagaa gtaaataaaa taaaaaaggc
    10141 aactatatgc agaaatgtcc tgtacatagt tgcctttttt attaccgtta tgctttttac
    10201 tctgttaatt tgttagaaaa aactagatac gcatctaaaa tcgtttggaa gaaacttaat
    10261 gttccttcaa cgatattacc attttcatca attagattcg caacgtttcc gatatatgct
    10321 tccggttgct gcaaggttgg cacattcaaa aagacaagtg attggcgtag atggtggttt
    10381 gcgccaaagc cgccgatccc acctggtgat gcagtaacga ctaaacctgg tttatgatcc
    10441 caaacactgt gtccataagg tcttgagcct acatctaaag catttttcaa tactgctggc
    10501 acagaacggt tgtattcagg agtaacgaaa acgacaccgt ctagtcccct cacttcctca
    10561 cgaaaacgag tccattcagc aggagcctgt tctggagttt cgagatcctc attgtaaaat
    10621 ggcagatcat cgatttttac aaatacactt tcgtaccctt caggaagcaa tttcgcaaaa
    10681 gcttctgcta cttttttgtt gtaagaatct tttcttaaac taccaataaa aaatccaatt
    10741 ttttttgtca tacgattttt cctccttcaa actatctata ataatcttac aaaagataag
    10801 taactggagc aaataaaaac acttactgac aaaagctaca tagaagatag attacttatt
    10861 tttaacaaaa aagaagtcta aaatcttcta ttttctaaaa aaaatcgaat ttaatcaagc
    10921 tgtaaagaaa aaaagcttta cagggtaaaa aaaaactgtt acactacatc ttgtgaataa
    10981 aacaatggag gtggaaataa ataatggcag ttaaaatccg tttaaaacgt atgggttcta
    11041 aaaagagtcc gttttaccgt atcgtcgtag ctgattcacg ttctcctcgt gatggacgtt
    11101 tcatcgaaac tgtaggtact tacaatcctt tgaaagaccc tgcagaagta gttttaaaag
    11161 aagacttagt tcttgactgg ttatcaaaag gtgcacaacc ttctgacact gtacgtaaca
    11221 tcctttcaaa agaaggcgtt atgcaaaaac accacgaagc taaattctca aagaaataag
    11281 gtgaccggat atgaaagatt taagcgactt agtcttaaca atcgttcgtc cgctagtcac
    11341 ttatcctgat caagtcaagt tagacgtcgt agagtcgaaa gacttttacg agtacaatct
    11401 aacagtggct cctgaagata ttggccgtat cattggaaaa caagggcgtg ttgctaaagc
    11461 aatccgcaca atcgtttacg gtgttcggat caatgcaccg aaaaaagtgc gtttgaatat
    11521 catcgatgat aaggaaaagt aaataaacgt gctgtactcg aattttcgag tgcagctttt
    11581 ttgttttttt tattaattga agaaatgatt atttggcaaa acaagcaaga aagcgtatcc
    11641 ttataggagg agggagtgaa cagccaatga gaaagaaaat gttatttatt ccatttgctc
    11701 tattgttaag cgcttgtagt tcggttactc aagaatcaga caatacacat ctatcaagca
    11761 gtatatctga aactgttacc agtccagaaa aaagtagtac caaaacggct tccaccactg
    11821 aacaaacaat ggctacctca aataatgaga aaaagactgc tttagaccag ttgaaagaac
    11881 aacagccaaa tgttcccatg cctctagatg taccagtctc ttcaggctat ctcaatatcg
    11941 cagcgacaca tacaaagcaa ggttattcta ttttatatta cagaacagat cgtcccctcg
    12001 ggttgaatgc tgacgaattg aatcaagaaa cgcctattgc aacctatcta tatcaatatg
    12061 ggtttgcttc tagtcaagaa acaatccaag ttttgcagcc atttgagatc gacacaaatg
    12121 gtcagcaagt ggacttaggt tctcgaatca cagggtatca gcaaggtgca gcaggttcaa
    12181 gttttcttga atggcaagaa ggaaactggc gtattcgaat ccgtgggaat aatatagaag
    12241 gccaagatcc cttactatta gctaaagaaa tcgtagctta tttggaagaa aacagtctac
    12301 cagcacctga acaatttggt aaaattactg ttgatatggg tgatacgacg aatcgagccg
    12361 tagaagtaag ctggcaagaa ccgaaaaatg cctatacgat cactcatcaa gatcctatgt
    12421 ctgcgttgaa gatggcagtt tctatgaaga ggttgtgaaa tcagcgcgct gatctgagcc
    12481 catcatttaa ctccaagtca caggaagtaa tcaaaaatag cacgccgcat ttttgcataa
    12541 ttttggctta ataccttaaa agaaaactag aattgcctct tcacacatgc taaaataaaa
    12601 cagacaaaaa agaaatgggg atataagttg actgaatact tgaatgtagg aaaaatcgta
    12661 aacacacaag gtatcaaagg cgaagtccgt gttatctcaa caacggattt cccagaagaa
    12721 cgttacaaaa aaggaacggt gctaacacta ttccaagacg gaaaagcacc tgtggaatta
    12781 acagtcaaaa gtcatcgcaa acataaaaat tttgacttat tgagttttga aggacatcct
    12841 tctatcaatg atgtggaaaa atatcgggat ggcatattaa aagtgtcaaa agacaactct
    12901 gtagatctag ctgaaaatga attctattac catgagatca tcggtctgca tgtattagaa
    12961 gatggaactg agttaggtaa agtaaaagaa atcttgtcac caggtgccaa tgatgtttgg
    13021 gtcgttcaac gtccgaaaaa agctgatata ttgcttccat atatcgcttc tgtcgtcaaa
    13081 gaagtcgatt tagaagctgg agtggtccgt gtagaaattc cagaaggact gattgacgat
    13141 gaagattgat gtattgactt tatttccaag aatgtttgaa ggtcctatgg gggaatccat
    13201 catcggtaag gctgtagata aaggattatt agatatcaat atctctaact tccgcgatta
    13261 ttcagataac aaacatcaga cagtagatga ttatccatac ggcggtggag caggtatgct
    13321 gctcaaagtc cagcccatct atgataacat ccaagccatt gaaaaagctg caccggatgt
    13381 caaaaaaaga gtaattcttc ttgacccagc tggtaaacga ttcgatcaga aaatggcaga
    13441 agaattttca caagaagaac acttagtatt catttgtggt cattatgagg gatatgatga
    13501 acgtatccgc acattagtga cagatgaagt ttccttagga gattatgtcc ttactggggg
    13561 agaattaggt gcgatggtca tgatcgatgc aacagttcgg cttttgccag atgtgttagg
    13621 gaatcagact tcagctcaaa cggattctta ttcaaccggt ttattggaac atccccaata
    13681 tactcgcccg gcagaatata aagggatgaa agtaccagaa gtattgacaa atggaaatca
    13741 taaattgatt gaagaatggc aattaaaaga atcactaaga aggacctatc aacgtcggcc
    13801 tgatcttttg gaaacacttg aatggacacc tcaaatgacg aaatttttag aagaaatcaa
    13861 gaaagaagaa caagaaaaaa cagcagatga agccaagtga ctttttctaa aatcttcttt
    13921 acagtaggtt gataatatgt tagtatttta tggtgagtgc aaaagcactt aactattacg
    13981 atattccgct gtgagaaaag ctcataagaa tatttggaat aaggagaaga aaaccatgaa
    14041 tccattaatc gaagaattaa caaaagaaca attacgttct gacatcccag cgttccgccc
    14101 tggtgacact gtgcgtgttc acgcaaaagt tgttgaaggt actcgtgaac gtatccagtt
    14161 atttgaaggt gttgttatca aacgccgcgg tgctggaatc agcgaaactt atacagtacg
    14221 taaagtttct aacggagtgg gcgttgaacg tacattccca ttgcatacac cacgtgttgc
    14281 aaaaatcgaa gtagttcgct acggtaaagt acgtcgtgca aaattgtact acctacgtgc
    14341 attacacgga aaagctgctc gtatcaaaga aatcagaaga taaacacgga aaacttcctt
    14401 ggaaatctga aatttgtgaa aagtccttgt atatcaaggg ctttttcttt tttctctatc
    14461 acagttttaa gccatttttg gctgttttgg accatttttc aatcatattc ccttaaaaat
    14521 tgtcctagat tgtccgacat tgactatcag tgtcgtcaaa atagggcaaa atttagtagt
    14581 cagcttgacg acaaatataa tacgaaaaat accaaaacat ttaccgaatt tagcaacttt
    14641 tgaacccaag tttctcaaag ggtcagctat tagcaaaaaa gacaaaacat gtacttttct
    14701 actaaaaagt tgatgtgata ggcttctatc taaataacta ttaggagttt ttatcgtgaa
    14761 gcaaaatgat ggacgtatca tttggaaaaa tcaaagtgag ttaaaactga ttttaacaat
    14821 taatgaattc atcgaaaaac acggaattac atctagccgt caataccaga aaaagctatc
    14881 agaaaatcca aattctgcac caagtatgtg gttcattaac aaaaaatatg gatcatggga
    14941 gaatttattg attagtatag gacgagaaaa tactgggtat ggaaaatggg ctagaatgtc
    15001 agaacaagaa ttattggaaa tagtagaagc ctttattaag tgcgagaaga taacctctca
    15061 acgaatgtac gaacaaaaat cagtagggaa gaatattcct tcacttagta ccattaaaaa
    15121 gatgttagga gatatacgtc cactttttaa agaaaaaaat gatggatctc gatttactga
    15181 tttcgaactg ctgttagaac taaaaaatga aataatccga ttaaaactac aggatgattt
    15241 atcaatgaca aagtttcgaa aactagttca atccccaaaa ctaccatcag ttgatacaat
    15301 tatgaaaaga acgaacaaaa attgggagga attgatggca gagattggat ttgattatcg
    15361 aagaatcaaa atttataagc agagaaacaa cctatccaag acaaagaaaa ctaaatagta
    15421 tcactctaaa tcagacgttc aaaattaaaa tttggacgtc ttttttatta cccaaaaacg
    15481 aaaggagatt tattttatga aaaagccaag atttaagaat tggcgtttgc tcgcaacact
    15541 gagtctatta tgccaaacaa ttggtggatc gcttggccca acgattgcct ttgctgatga
    15601 aattactcat ccacaaacgg taactgtgga attggatttg gctcaccagt atgctgtcga
    15661 aggtacattt agcgatggtc gtcccatgtc agaagttacc gttccgcact atgcagttta
    15721 caatggtgtg aagcaagata ttttctgtat tgagccaggg gtgccgattt acaatgagtt
    15781 cactcctggt tatgagaaaa atccattgcc tgatatgtcg gagaaagcga aattagtttc
    15841 cgttttatgg aaggaagctg gtacggatgt ggatacacat attgtggccc agaagatgat
    15901 ttggcaagaa gttaatggct acacgcttca ctcaattaaa cgttctgatg gtagtgcagt
    15961 aaatatcgca gccattgagt caaaaatcaa tcaagccatt gcggattatc aaaagaaacc
    16021 aagcttccat aactccacag tgaaaaccgt gttaggtcaa tcgactactg tgacagatac
    16081 gaacggcttg aatttatcgg agtttgatga agttgtcgag aatatcgcaa atattgatta
    16141 tcgtgtgaac ggcaatcaac tagtgattac tccaaatgcc aattcaaaag agagtggtga
    16201 attaacccta aagaagtcag ctaatacagg aacaccggta gcttataaaa tggctggtca
    16261 acaaactttg atggcggggg caattgataa gcccaatacc tacacaatca aaattgatgt
    16321 ggaaactgag ggttctttga agattaaaaa agtcgataaa gaaacaggaa atgttgtacc
    16381 gggaaccgtt ttccatttag actttggaaa aacattacct gcaaaagacg tgaccaccga
    16441 taaagaaggc attgcgacat tggatgagat tcctcatggc gcgaaagtaa ccattactga
    16501 aaaatcagtg ccagctcctt atacgattga cactacacca atcaccgcaa ccattaaatc
    16561 tggtgagact atttctgtga cttcaaaaaa tactcgcgaa aaaggtcaaa tcattttgaa
    16621 taaaatgggg gtggaaacag gaactgatct ttggaacgac aaatactcat tagccggaaa
    16681 tacgtttgcc attcgcaaag acagtccaac cggtgaaatt gtccaagaaa tgaccacgga
    16741 tgaaaaaggt catgcggaaa caccaaaaga gattgccaat gcgttggaat tgggaaccta
    16801 ttatgtgacc gaaaccaaag ctagtaatgg ctttgtgaat acctttaaac cagtaaaagt
    16861 cgaattgaat tatgtcaatc aaaccgtggc tcttgttacc agtaacgtaa aagggcaaaa
    16921 ccaagaaatt actggtgaaa ccactttgac aaaagaagac aaagataccg gtcatgaaac
    16981 tcaagggaaa gctgagttta aaagagctga atacaccttg tttactgtta aggatggaaa
    17041 agcggtcaaa tggaccgaga actttaaacc agaattgttg aagggaacga aagcttctga
    17101 tgaaaccgta actttgactt tagatgaaaa gaatcaagtt gccgttaaac acttagcgat
    17161 taatgagtat tactggcaag aaaccaaagc gcctgaagga tataccttgg atgaaacaaa
    17221 gtatcctgta tccatcaaaa aggtggatga tagcgaaaaa aatgctgtga ttactcgaga
    17281 tgttgcggca aaagaacaag tgattcgctt tggctttgat ttctttaaat ttgctggatc
    17341 agctgctggg actgccgaaa ctggcttcaa tgatctgacc tttaaagtat cgccattgga
    17401 aggaaccagt gagattacag gtgccgaaga tgaagcaatt acagcttata acgagcaact
    17461 aggttttgat ggctatggca agtttgaaaa tcttccttat ggggattatt tacttgaaga
    17521 agtagaggct ccagaaggat ttcaaaaaat tacgccatta gaaatccgtt ctacttttaa
    17581 agaaaataaa gcggattaca ctaagagtga atacattttt acgattaccg aaaaaggaca
    17641 aaaacaacca attaaaacgg tgaccgttcc ttacgagaaa ctgacgaata aagcattttc
    17701 tgttagcttg aatcgtttga tgctctatga tttacctgaa gaagaagata gcttaacttc
    17761 tcttgggact tggaaagacg gaggcaaaga attgacagac cttgattcta ccgagctagt
    17821 tgataaattg agctataact tgcatgaaat caaagaagac tggtatgtgg tagcgcaagc
    17881 cattgatgtg gaagcgacaa aagctgccca agaaaaagat gaaaaagcca aaccagtggt
    17941 aattgccgaa acaaccgcaa cgttggcgaa taaagagaaa acaggaactt ggaaaatttt
    18001 gcataaatta accgcagaac aagttttgga taaaaccatc gtcttattca actatgtgta
    18061 tgaaaacaag aaaccctatg aagcaggtga tgatccagta gcgaaagatg ctagcttgaa
    18121 caatcaagcc caaactgtca attgtacggt ggaacgccat gtttccatcc aaacaaaagc
    18181 ccacctagaa gatggttcgc aaacctttac tcatggggat gtggtggata tgttcgatga
    18241 tgtgtcgatt acccatgatg tactggatgg ctcaaaagaa gcttttgaaa caattctgta
    18301 tgcattactt ccggataata cgaccaaaga aatttggaaa tctggcaaaa ttgattatga
    18361 agtgaatgac aaagaattca ctaaaaccgt acttgcggaa aaagtggaca caagtaaata
    18421 tccagaaggt acaagtttta ccttcaaaga aattaactat ggcaaagacg gaaacatcaa
    18481 tgggaaacac aatgaggatc taaaagaaaa aactcaaact ttaacaccta aaaaagttcc
    18541 gacaacacca agtgcaccag aacaaccgga aataccaact gttccaagtg actctcaaga
    18601 atctagtcct acagtaaaga cattcccaca aacaggggag aaaaattcta atgttctgct
    18661 gtttattggg tttaccttga tctttgcgac tgctgggtat tatttctgga atcgccgaaa
    18721 ctaaggtgat gtgatgaaac aactaaatag gaaaaaccaa cgtgcgcgac cgcctcctaa
    18781 aaaaagtggt cgcgctattt ttgtatccaa aactaaaaat gaaaagagga aaagaagatg
    18841 gaattgaaat ttgttgtgcc agatatggcc gaaacctttg gaaagataag gtatgccggc
    18901 gaaggcgaag ttttaactga aggatatggg cggaatacta cagtaattgg tcgtagttat
    18961 catttgtatt ccagtaagca acgagccgat gatattgaag tggtggtagc tgcggaagcc
    19021 ggcgaaaagg attttgatca agatcaacca ctaaaagccg tgaatcccca tttggttgcc
    19081 aaaggctatg agattgagaa tcgtgggttt accgactacg tgttgtatgt cgatgattta
    19141 gtgaaagcat aggaggaaaa gaagatgaga ttaacagaag gtattgttgt agattcagga
    19201 ctaacgtttg ggaaattacg attttccgca ttacgccgag aagtacggaa gcaaaatgag
    19261 gatggaacgg ttagtaacga ggtaaaagaa cggacttata atttgaaatc ctctgcgcaa
    19321 ggtcgaatga tccaagttag tatcccagca aatgtaccct tacgcgagtt tgcctatgac
    19381 gcagaggtag agttggtcaa tccaatcatg gatacggtcg ccaattatgt tttccgagaa
    19441 ggaactactg tcaattggtt cattaaggcc gatgatttag tcttgaaacg acaaccagat
    19501 cagggaaatt ctacaaacca aaatgaagga aagaaatagg tgaagcgtat ggaaattaat
    19561 gttgaacata ttttagattg tctcgatcaa tatggaaaag gtgagctaac ggaggaacaa
    19621 ctcactaaag cattaaccta tgatgaaaaa atgtttctga ttatgcatca agggttactg
    19681 gaagtaggta acgatgccga agaagatttt gatgtactga attggttagg ggaagaagag
    19741 tccttcttta tggttatcga agtaaatgaa agtctatgtc gagaagccga aaccgtattg
    19801 gaagaaattg gtgtggaaat gccggatgcc attgaagttt ttttaaagca actagtggaa
    19861 acgaaacaac tccctatagc agtaaatgac tagcataact gcttgaaatt ggatcaatga
    19921 aatcctatga agcttttttc gattggaggt ggaaaccata aaaatgtaca aagggcatcg
    19981 tatacgggca ggagatcagc acttggttta tcactttgtt cttggctggc tactcgctct
    20041 gttcatcggt tggatgagcg tcttttattt tcaagagctt agacaatttg atatttctaa
    20101 gctatcactt tctactatag aaatcgttcg ttctataaaa gatttaatct atttgctagg
    20161 aagtctcgtt ctttcaggaa gcacgatgtt gctttatata cacttttttc aggatcattg
    20221 gcgcagtttg tggcatcgac aaaagctagc ccggatgatt ctagaaaatc attggtacga
    20281 agtaaaacaa actcagagtg aaggattttt caaagacctc aatagtagtc gaaccaaaga
    20341 gacaatcagt tacttcccca aaatctatta ccgtatgaag gatggtttac tttctattcg
    20401 cgttcaaatt tcactgggaa aatatcaaga tcagctttta aagctggaaa agaagttaga
    20461 aagtggtcta tattgtgaac tagtagaaaa ggaactcaaa gactcctatg tggagtacac
    20521 tttactgtat gatataattg ccaatcgaat tgggatagac gaagtagtgg cagaaagtgg
    20581 ggctttgcga ttgatgaaaa atcaagtatg ggcttatgat tctttacctc atatgttaat
    20641 cgctggcggc acaggtggtg ggaagactta ctttttactc actatcatcg aggctttatt
    20701 aaaatctgat gccgagcttt ttgttcttga tcccaaaaat gcggacttag ccgatttagg
    20761 tacggtaatg cctcatgtct attcccaaaa ggaggaaatt tctgcttgtg tggaagattt
    20821 ctatgagcgc atgatgactc gtagcaaggc aatgaaagaa atgcccaact acaaaacagg
    20881 agagaattat gcgtttcttg gacttccacc aaacttttta atctttgatg aatacgtggt
    20941 ttatatggaa atgttaacga cgaaggaaag tgcggtgatt ttgaataagc tcaaacaaat
    21001 cgtgatgtta ggtcgtcaat ctggtttctt tctgattcta gcttgtcaaa gaccggatgc
    21061 gaaatattta ggagacggga ttcgcgatca atgtgcgaca tgtttctaac tgaaaaggtt
    21121 aggcacttaa aagaagaaaa cataagtttc cttttaagga gaactgatat tttgagcagt
    21181 ggaatgatgg ggtaacgccc tgaaacgctc ccttaatact ccgactggct gtttaacata
    21241 tagctgttag atggtcagaa gctcggtgaa gtcggctgaa agttaccgta aatatgataa
    21301 attcatatac gaaagttgtt cagaggtgaa tgatgtaacc tataggtcgg aggtctataa
    21361 aatactcacg gtgagaatgt aagtaatact actgacgaac ttgcgaatga aagaatctat
    21421 acacggactg tatagaaatg tacaggattc taccgtatca acggaacaga atgtatgttg
    21481 tggtttagta agattattgg ttatgaacaa ccatgcaatg ttacaggcat tggaaatata
    21541 caggttcaaa gcaagcacct aaaagtatat ataaagataa aaatatcgaa acatgggaag
    21601 ctggcaatgt ggaggaaact atattccatt gaaacatttg tgacgaagaa taataagcac
    21661 atttatgcca gtgaaagtgg tggcacagta ccaatgagga tatagaaata tatcggagga
    21721 atagccacta gtcaaaagaa atcgttaatt aaatgatgta tttcatagaa tcgagtaaga
    21781 caaaataaac actacaacct aagtaaacaa aggtagtggt gctatgaata aagtaaaaac
    21841 aaataaaaca cttcgtcata gtgaatacta tggcatgaca caaatatttg atgaactgta
    21901 tgtaaaaagt gataaaaaag aagtttttac agagctcatg acaattatta tgagtgatga
    21961 aaatattcga ctagcataca gaaatatcaa gaataacaag ggcagttata cagcgagtac
    22021 cgataagaaa agtattcgag acattaaaac actgtcagaa gatacctttc taactgaggt
    22081 taaagttctt tttcgctgtt acaaaccacg agcagttaga cgtgtagaaa ttcccaaacc
    22141 aaatggaaaa acacgccctc tgggcattcc atcaatctgg gataggttaa tacaacagtg
    22201 tattttacaa gtcttagaac cgatatgcga agctaaattt cacaattata gttatggatt
    22261 tcgaccaaac cgttccacac atcatgcgat tgctacctgc aatcgactgg caaatagggg
    22321 gaagctacac tttgtagtag atgttgatat taaaggattc tttgataatg tcaatcactc
    22381 taaacttttg cgtcaaatgt ggacgattgg aatccgtgat aaatggctat taggtattat
    22441 tcgatccatg ctaaatgctc ctatagtcct accaaccggt aaagtcgaac accctaaaaa
    22501 aggtgtacct caaggtggtg tcctatcccc tttactatct aatatcatat tgaatgaatt
    22561 agattggtgg gttgcttcac aatggcaaaa taccacgatt gagacagaaa agattatgga
    22621 taggcgagat aaaggcaaag gcattgataa gactaatcag tatcgggcat taagacgaac
    22681 aaacttaaaa gaaatataca ttgttcggta tgctgacgac ttcaaaatct tttgtagaaa
    22741 acgaagtcat gcagataaaa tatttcacgc aacgaaaatg tggcttaaag aacggttatc
    22801 acttgaaatt agcgaagaaa aatccaaaat tgtcaatctc aaaaaaggta aatcagaata
    22861 tctaggattt gaattaaagc taatcaagaa aggtaaaaaa tacgtagtcg aaagtcatat
    22921 gagcaaaaaa tcaatgacaa gagttaaaat ccaattaaag aaacaattac gtaaagttgc
    22981 cagaccgaag aatcattgcg aacaagcaaa agaaattgga ttatataatt ctatggtgat
    23041 tggaatccat caatattatg gaattgcaac ctgtgtaaat ctcgattgca gtaaaatagc
    23101 ctatacacta aaaccgttca tcaatcacaa actgccgaca aagaaacatg gaaagatatt
    23161 aaatacattt atcaaatcga agtatggaaa aagtaaagaa atgcgatggt tgaataatgt
    23221 gccaattgta ccgctcaact atgttcagtt tagacttgct gtccccctat cagagggaac
    23281 ttgcaagtac actgaaagtg gacgaagcaa gatacacagt aaattaaaat tagacctagc
    23341 ccttttactt cacatgatga gaaatagtaa ttatgaaaga agtattgaat ttgtggataa
    23401 cagaatatct aaatattctg ctcaaaaggg aaaatgtgct atcacgggta aatttctcga
    23461 atacgaagaa atccattgcc accatatcgt accagtaaaa caacagggta cagacaaata
    23521 cagcaacctc attattattc acaaaaatgt tcacgcatta gtccatgcta tcgaagaaaa
    23581 aatcatacac aaatacctga atgtattaaa tctaaccaat gaacaaatag aaaaactaaa
    23641 tgaattacgt gtcaaagctg gtaatagtgt tttaacagtt taacttgaaa aatatatcat
    23701 acttaacatt cttttgatgg aacgccgtat gaagtgaaag tttcatgtac ggtgtgaagc
    23761 gggggaaaat ctggagatga catcaaagga ttacctatcg c
//
LOCUS       DASHWW010000034        23656 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.034, whole genome shotgun sequence.
ACCESSION   DASHWW010000034 DASHWW010000000
VERSION     DASHWW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.034"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            258..533
                     /locus_tag="U2R64_001596"
     CDS             258..533
                     /locus_tag="U2R64_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918418.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            546..2624
                     /locus_tag="U2R64_001597"
     CDS             546..2624
                     /locus_tag="U2R64_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HEM8918419.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2784..4670
                     /locus_tag="U2R64_001598"
     CDS             2784..4670
                     /locus_tag="U2R64_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8918420.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4682..5629
                     /locus_tag="U2R64_001599"
     CDS             4682..5629
                     /locus_tag="U2R64_001599"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEM8918421.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5649..6176
                     /locus_tag="U2R64_001600"
     CDS             5649..6176
                     /locus_tag="U2R64_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8918422.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6239..6892)
                     /locus_tag="U2R64_001601"
     CDS             complement(6239..6892)
                     /locus_tag="U2R64_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEM8918423.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7024..7866
                     /locus_tag="U2R64_001602"
     CDS             7024..7866
                     /locus_tag="U2R64_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8918424.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8024..8920
                     /locus_tag="U2R64_001603"
     CDS             8024..8920
                     /locus_tag="U2R64_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEM8918425.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8923..9636
                     /locus_tag="U2R64_001604"
     CDS             8923..9636
                     /locus_tag="U2R64_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEM8918426.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9656..10174
                     /gene="msrA"
                     /locus_tag="U2R64_001605"
     CDS             9656..10174
                     /gene="msrA"
                     /locus_tag="U2R64_001605"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEM8918427.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10171..10398
                     /locus_tag="U2R64_001606"
     CDS             10171..10398
                     /locus_tag="U2R64_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEM8918428.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10550..11101
                     /gene="lepB"
                     /locus_tag="U2R64_001607"
     CDS             10550..11101
                     /gene="lepB"
                     /locus_tag="U2R64_001607"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEM8918429.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11184..11684)
                     /locus_tag="U2R64_001608"
     CDS             complement(11184..11684)
                     /locus_tag="U2R64_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEM8918430.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11963..12361)
                     /locus_tag="U2R64_001609"
     CDS             complement(11963..12361)
                     /locus_tag="U2R64_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8918431.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12621..13481
                     /gene="ylqF"
                     /locus_tag="U2R64_001610"
     CDS             12621..13481
                     /gene="ylqF"
                     /locus_tag="U2R64_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEM8918432.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13474..14241
                     /locus_tag="U2R64_001611"
     CDS             13474..14241
                     /locus_tag="U2R64_001611"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEM8918433.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14297..15154
                     /gene="dprA"
                     /locus_tag="U2R64_001612"
     CDS             14297..15154
                     /gene="dprA"
                     /locus_tag="U2R64_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEM8918434.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15276..17354
                     /gene="topA"
                     /locus_tag="U2R64_001613"
     CDS             15276..17354
                     /gene="topA"
                     /locus_tag="U2R64_001613"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEM8918435.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17323..18699
                     /gene="trmFO"
                     /locus_tag="U2R64_001614"
     CDS             17323..18699
                     /gene="trmFO"
                     /locus_tag="U2R64_001614"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HEM8918436.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18897..19802
                     /gene="xerC"
                     /locus_tag="U2R64_001615"
     CDS             18897..19802
                     /gene="xerC"
                     /locus_tag="U2R64_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HEM8918437.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19839..20387
                     /gene="hslV"
                     /locus_tag="U2R64_001616"
     CDS             19839..20387
                     /gene="hslV"
                     /locus_tag="U2R64_001616"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HEM8918438.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20401..21801
                     /gene="hslU"
                     /locus_tag="U2R64_001617"
     CDS             20401..21801
                     /gene="hslU"
                     /locus_tag="U2R64_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HEM8918439.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIASDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21819..22610
                     /gene="codY"
                     /locus_tag="U2R64_001618"
     CDS             21819..22610
                     /gene="codY"
                     /locus_tag="U2R64_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEM8918440.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22692..23567
                     /locus_tag="U2R64_001619"
     CDS             22692..23567
                     /locus_tag="U2R64_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEM8918441.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8192 a         4081 c         4983 g         6400 t
ORIGIN      
        1 atttttgtcg cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga
       61 aagtaaacat ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata
      121 ctatttggaa tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg
      181 atgaaacaat gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg
      241 tataggagat ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc
      301 gctatggcgc cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa
      361 atatattgat gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa
      421 aacgtgtaca gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa
      481 ttttaaagaa aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat
      541 ggacgatgga atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca
      601 tagctagccg cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg
      661 tattaggtct gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta
      721 tgattattgc accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca
      781 aaaatttcgg gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg
      841 taggtgcgac gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg
      901 gagcagcgtt aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata
      961 tccctaaaaa ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg
     1021 ttactgcctt ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg
     1081 cggggatgag tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct
     1141 ggttcaaaca aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt
     1201 atctgctgat cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg
     1261 tatctggaat cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa
     1321 tctctgtgtt tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt
     1381 ttacactgaa tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc
     1441 cagtatgggg agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct
     1501 ctgtcatgct ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg
     1561 gcagtaaaaa gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa
     1621 agggaacagt cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt
     1681 tttaccagcg gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca
     1741 tagggatcat tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga
     1801 atgctttgat gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg
     1861 atcgtaatac aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga
     1921 tacgtgatct gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac
     1981 aagcactgat tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc
     2041 tttcttctaa tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca
     2101 caagccagat tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa
     2161 tcgttctcca tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta
     2221 gtgatgaaga tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg
     2281 aaagtttaga taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc
     2341 aacgcaaact tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc
     2401 agcaagatag tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca
     2461 ttgatgaata cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga
     2521 atatcaattt gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat
     2581 ttgcgtttcg agcaaagtca aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc
     2641 aagttttata aaaaacaaaa catatcagaa caggatcgaa tcggtcctgt tctttttttg
     2701 agaacacaaa aagaacaaat accaaaaaaa ttttcctgaa gttcactatt tttatgatac
     2761 aatatccaag ataaggaggg aacatgttga aagaattaaa agtaactgac ctcaaaaaaa
     2821 cttatggtga aaaagatttg tttgaccaga tttctttttt ggtccacgaa aaagaccgta
     2881 tcgggttgat tgggacgaac gggacgggta aaacaagtct cttaaatatt attgccggta
     2941 tcgatagcag cgacggtgat cggcaaacag tgttttatcc aactgattac cgtattggtt
     3001 atctttctca agcagctgaa ttttccgatg aattaactgt tctccaagca gtctttcaag
     3061 gaaacagccc cttgatccaa actgttcgag catatgagga agcattgatc gaactagggg
     3121 aaaacggaga agaccctgat gtgcaaaaac gttatgctaa agcagaagaa caaatgaata
     3181 aagaagatgc ttggactaca gataccaacg caaagattat tttgcaaaaa ttaggaatca
     3241 gtgaattaga taaaaaaatc agtactttat caggtggtca gaaaaaacga gttagtctgg
     3301 cgcaagtgtt gattgatgaa cccgatttac tattactaga cgaaccaaca aaccatttag
     3361 attatgaagc gatcgagtgg ttggaaaact atttgaaaca ataccgtggc gcactattga
     3421 tggttaccca cgatcgttat tttctagata gagtagcaaa ccgaatcttc gaactttcat
     3481 ttggaaaatt atacgagtat aaaggaaatt atgaagctta cgtcttagaa aaagcagaac
     3541 gtgatcgtgt agaagtagaa caagaagaaa agcgcaagcg gctttataaa caggaattag
     3601 cttggatgag ggctggcgta caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt
     3661 tcgaagatct aaaggagaac ttgtaccaag taaaccaaga agatgattta gagctgaacc
     3721 tagcgacaca acgtttaggg aaaaaagtac tggaaatcaa agatggcagt taccgtataa
     3781 atgaccaaac actgctagaa catttagatt tattgattca atctcgggaa agactaggta
     3841 ttactggtaa aaatggtgcg ggaaaatcga cattgcttaa tattctagct ggcagaattc
     3901 ccctggatag cggtacaatg tctatcggtg aaacggttca tcttgcgtat tatacacaag
     3961 aaaatgaaga aatggcacca gataaacgga tgattgctta cttacaagaa gctgctgaag
     4021 aagcaaaaac agcagatggc agtcaaatcg gagtagcaga attacttgaa cgatttttat
     4081 ttccaagatt tatgcatggg acactgatag gcaaactttc aggcggagaa aaacgccggt
     4141 tatttttgtt gaaactgctg attcagcaac ctaatgtttt attattggat gaaccgacca
     4201 atgatttgga catagcaaca ttgacgattt tggaagatta ttttagaagt tttccaggtg
     4261 ctgtgatcac tgtttcccat gaccgttatt tcttggacaa ggtagcagat aagttattag
     4321 tattccaagg aaacggaaaa caagaacttt attacggaaa catgtccagt tatttactga
     4381 agcaaaaaga gacccagcag cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac
     4441 ctgctgaaaa gaagaaatta tcttacatgg aacaaaaaga atgggaaacg attgaagatg
     4501 agattgcaga acttgaagaa aaaatctcat tgctccaaga agagatgaat catcaaggag
     4561 ataatttcac tcgattacaa gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg
     4621 aagaaaaaat ggcacggtgg gaatacttga gtgaatgggt agaagattag gaggaaaaag
     4681 gatggaacaa gcgtatcttg acttaggaag aaaattgttg gaagaagggc atcgtaaaga
     4741 agacagaaca ggcacaggca cattaagctt attcggatac caaatgcggt ttgatctgca
     4801 aaaagggttt cctttgttaa caacgaaacg agtacctttt ggattgatca aaagcgaatt
     4861 gctttggttt ttaaaaggag atacgaatat ccgctatcta ttacaaaata aaaaccatat
     4921 ttgggatgaa tgggcatttg aacgctacat caaaagtcca gactataatg gaccagatat
     4981 gactgatttt ggccatagat gtttgacaga tcctgaattc aatgaagaat ataaaaagca
     5041 gagcaagctt ttttgcgaga agatcctaac cgatgattcc tttgctgaaa catacggcga
     5101 tcttggacac atctacggct atcaatggcg tcactgggaa acaaaagacg gtggctttat
     5161 cgatcaaatc aaacaagtga tcgaagcaat caaaaagact cctgattcta gaagattgat
     5221 cgtttctgca tggaatccgg aagatgttcc tagcatggct ttgcctcctt gtcatacgat
     5281 gtttcaattt tatgttcaag agggacggct aagctgccaa ttgtatcaac gcagtgggga
     5341 tgtgtttcta ggcgttccgt tcaacattgc aagttatgcg ttgctgactc acctaattgc
     5401 acatgaaaca ggtttagcgg ttggcgaatt tgttcacaca ttaggagatg ctcatcttta
     5461 tatcaatcat atcgaacaaa tgaaagaaca attgagccga gaaatacgcg catttccgac
     5521 tttagttttg aatcaggaaa agcagtcagt atttgatttt gagatggaag atatccaatt
     5581 agaaggatat gacccacatc cggcgatcaa agctcctatc gctgtttaga atcagaaagg
     5641 atgagaaaat gttagctgca atttgggcac aggatgaaaa cggattgatt ggaaaagaag
     5701 accgtcttcc ttggcgtttg ccaaatgatc tgaaattctt caaacaaatg acagaagcaa
     5761 atacactagt gatgggacga aaaacattcg aagggatggg tagccgtccg ttgccgaatc
     5821 gtcagacgat tgttttgacg agagattctt cctataaagc agaaggcgtg catgtcatgc
     5881 atagtgtgga agacgtgctt gctctggaaa aagaaacaga cggtatcttt ttcatcgctg
     5941 gagggtcagc tgtttatcaa gaatttctgc cattttgtac gatattatac cgtacagtca
     6001 tccatcatgt attcgatgga gatgcttatt ttccacctgt tgactggtct gattggtcac
     6061 tgatcaatac tagtcaagga gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa
     6121 cgtatcagcg taatgagaat cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa
     6181 gctatggata gactagctgt tatttagagc tgtcccatcc atagctttat tttttttatt
     6241 aagtaaagaa taaaacagag aagtacataa aacctgcacc taacataaca aacaaatgcc
     6301 aaacaacatg catatagcgg atagaattca agctataaaa gaatgcgcct atcgtgtaag
     6361 aaagcccgcc tgctaccatc aaaataacac cagtcattcc aagagagtga taaagaggaa
     6421 cagcagccac gacacagagc caccccataa aaatatagat gatcgtagat acttttgata
     6481 ctctctcccg tttatgcaac gtcaacgctt tatatataat gccaagaatc gcaaacaacc
     6541 agattaatac aaataaagtc caacctagcc atcctcggat actcagcaaa caaaaaggag
     6601 tataacttcc tgcaatcaaa agaaaaatcg aactatgatc gaatacttgg aacacctttt
     6661 ttgcttttgt aaaaatcaat gaatgaaaca aagtagacgt taaaaataaa agaatcatca
     6721 tcgatccata gatagcataa gagacaatat ggagggagga atgcaagtgg gcacctttta
     6781 ctaaaagaac cactagtccc gcgatactca atccagtccc aattccatgg gtgactgcat
     6841 taaacacttc atttaatatt tcatacgttc gattaaattt cgttttttcc atgaaaacgg
     6901 ctcctttact aggtgtaatt aatgaaaaat cattatttgt ctgttatact aaaaatagaa
     6961 attgtcttac atgtagttta acatgaataa ggcatcttgt taaagaaaga gagagagaaa
     7021 ataatgacaa atgtaaaaat cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc
     7081 gatgctttag gcattcgtgt catgccgcta tccatcatga tcgacggaac agtatatccc
     7141 gatgatgacc aactagacgg cgaaagattt atggaaatga tggcgaaagc aaaaaatctg
     7201 cccaaaacaa gccaaccacc aattggagaa ttcatctcga tgtatgatga gctaggagaa
     7261 gacggcagtg aagtgatttc gatccatatg acaaaaggct tgagtggaac agtagaagca
     7321 gcaagacaag ccagtaatct aacaaaaacg aaagtaacgg ttatcgacag tgataccact
     7381 gaccaaggat tatcttttca ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca
     7441 gtagagaaaa tccttgaaga agtcaaaaaa gtacaagaca atacaaaatt atacatcgga
     7501 atatccacac tagataactt ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg
     7561 tctagtgttt tgaacatacg cgtggtgatg aatttcgccc attctgaatt aatccctgta
     7621 actaaggggc gaggaaagaa aacgttcgat aaatggttta ataatttgaa aaatgaactg
     7681 aaagaattgc caaatgtgcg acaaatcggt atttcacatg cggatgcaaa agaattggcg
     7741 caagaattca aagagggttt gcaagaatta ttcccggaca tgcatatccc tgtactgcat
     7801 acgaatccgg ttatcgctac gcatactggt aaagacgcgt ttgcaatcat gtattatgta
     7861 gattagtcga aaagaggata agccctcagc ctgaaaggct tgcagcttat tctctttttc
     7921 tttataaaat taggaaaata attgttttct tttttcataa agactacctt tttgataaaa
     7981 tttttgataa cattagaacc aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg
     8041 acatttgatc ctcgttttgt tcccattatt aattgcgatc atcatctatg caggtttagc
     8101 tgcttctata ccgaaagctg gcccactaat gaaaccagta actactgtga gagaagatcc
     8161 aaataaaaaa gaaaaacttc actacatagc tatcggagat tcgctgactg aaggagtagg
     8221 agatcaaacc aagcaaggag gattcgttcc ccttgtcgca aatgatctaa aagaccgtta
     8281 taatttgacc gcggttgaaa cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat
     8341 cttaaagcga gtaaaaacaa aagaagaaat tcgaaacaat atcaaaacag ctgattttat
     8401 cacactgact gttggcggta atgatttgat gaaagttatc caaaataatt tattcgggtt
     8461 aacggtcaac tcctttaaaa agccactgaa aaactatcag gaaaatgtca cagaactatt
     8521 ggaagaattt cgatccctca ataaaaccgc acctatttac attttaggca tctacaatcc
     8581 attttatttg aactttcctg agatcactga catgcagaca attgttaaca attggaacaa
     8641 aggaacagaa acggtgacaa aaaaaatgcc gaactgctac tttatcccaa tcaatgattt
     8701 gctttatcaa ggattgaatc aggaagtagg tgtcacagaa gaaggaacag atcaaacaac
     8761 tagcacgaca gaaaatctaa atggcatcaa aaataatgtg ctctatgaag aagatcattt
     8821 ccatccaaat aatttaggtt atcaattgat ggcaaatgca gtgagagatc agctgatcga
     8881 gacacaaaac caatggttag agaaggagga tgatcaataa acatgaaaac aagatctgac
     8941 gtatcttcaa acaaaacaaa gaaaacaaat tactggaaat tcgccttcct tatccttctt
     9001 ggggtagtac ttggttcgac cgtattttta ggcagccgta tttttgctaa tcgggaacca
     9061 gaactcccag aaataccagc tcttacggaa agacaaggag atcctgtctt aacgatcaat
     9121 tcaaataaag aaaaagtcaa tcaaatcatc agctttttcc ttagtgagta tcaaaaagat
     9181 agtgatattg aatataaatt ttatttggaa aatgaagcac tactcaatgg tactttcgaa
     9241 gtactaggtt ttcctatcga tttctattta tattttgatc cgtatgtgat ggaaaacgga
     9301 aatgtccaac taaaagctag aagtctttct atcggaacat tgagtttgcc aatcaaagat
     9361 gtgatgaata tgatcaagag aaactataaa ttaccagatt ggatcgaagt caatacagat
     9421 gatctgacta tcatgcttag gttggatcaa ttccgaatgc aaaacgggat gtatattaaa
     9481 gcagataaaa tcgacttagt aaatgatgac attcggttta gtctatattt gccaaaagat
     9541 acctctgatg cttcaaacaa ctcaaatacc aacaaaacta gcaccagcag tactgaaagc
     9601 aagacaaaag aaaataaaaa atcatcggat gagtagtatt agagggggaa tcataatgga
     9661 acgagcaata tttgcaggag gctgcttctg gtgtatgatc cagcctttcg acacgcttcc
     9721 tggtatccat acagtgatgt caggatatac tggagggcat gtaccagatc cgacttatga
     9781 acaagtaaaa agccaaacga ctggacatac agaagcagtg gagattatct atgatccaac
     9841 attgatttca tatgaacaat tagtagaact ttactggcag caaactgatc caactgacgc
     9901 tttcggacaa ttcgaggatc gcggtgacaa ttatcgcccg gtgatctttt atttgacaga
     9961 agaacagcgg atcattgctg aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga
    10021 acagccaatc gttacaaaaa tcgaaccagc ccaaccattt tatctagcag aagaagacca
    10081 tcaagagtat tataaaaagc atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc
    10141 ctttatcgaa gaaaattgga ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg
    10201 acactgcgag gcggtggcac acatgatgct ttatctgttt tcgctacaga agccggtaaa
    10261 gacatccaat ttcctaagca cagctctagc tacgaagaaa tttctaatta tctggaactg
    10321 aatgtcgact atttgccgtc catggatatc tttgacgaag catgggaaaa atatttagaa
    10381 aataatcatg acatataaga gatagttttg tactttatga tcaaaaaagt tttttgtcca
    10441 atagcctaat tgaaagaatt atttttattt cagctatcta gtcgcatttt tttgatattt
    10501 ttcttataat aaagaaagaa tgaaaaaaag agggatggat tgatagagat tgacaaaaaa
    10561 acaacgctat attaatcgct tctggcttgt attcaaatac ttacttgttt ctgtattcct
    10621 tgcgttcatg ttgcggggat ttttattcat cccggtacca gtggaaggca attcaatgga
    10681 aaacgtgttg aagcaaggtg atatggttgt gatggaaaaa ttttcggaga tcagacgatt
    10741 tgatattgtt gtttttcaat tagcagatgg cacgatttat atcaaacgag taatcggtct
    10801 tccaggagaa aatgtcagct accaaaatga tcaattgaag atcaatggga aagtagttaa
    10861 ggaaccttat ctaactaaaa acctgaaatc agatcatgca aatgcatcct atacgacgga
    10921 ctttacacta caagagctaa cgggacaatc caagcttccg gaagataatt attttgtact
    10981 tggagataat cgaagagttt caaaagatag tcgttcgttt ggcacgatca ataaaactga
    11041 tattctaggt aaagcaagat ttgtctatta tccacttgat gaaataaaat ggatccagtg
    11101 agaaacaata aagcgtgcag tctgttgaga ctgcacgctt tattgtttaa tccaaaatca
    11161 gtttactacc ttagtacgta aaatcaaaca gctcgtttaa acacttttct agcctctaaa
    11221 gttttgataa atgaataaac aaccattatt tgaataggga tttggatcat attcctgatg
    11281 aatctaccta gaaaaattac tttgaaatct gcaccaaaca aaacagacat cagccaagaa
    11341 ttgataaaaa ggctgactgg gatcataatc aataattggg cagcgatgac ggaaggcagg
    11401 tttatctttt tatgatataa aaataagcca ttaataaatc caccaaggaa agccgtgata
    11461 agaaaagcag cttgaaacgt tcctgaacca aatatcgtga aatttaaagt gttcgacaac
    11521 atttcaagca aaccagccca gatcggtcca tatagataac ccataagcgc catacttaaa
    11581 aatccgaatg tgatttgaaa ataagcagga ccaatcgcta tcttgtataa gatgacatca
    11641 agggctaata aaagagcaga ggtcgacaac aatcttgcat tcatttcggg caatctaaaa
    11701 acgtcttttg caatcaaagt gttcaaaata ttctctcctt tgtcagttaa taataaaagg
    11761 ataccataaa atcaccaatg tgtcatgaca cattggtgat ttacatacac tggcatctaa
    11821 caattaaaaa aagggtgaga agactgcttt tataaactgt aaaaaagaga ttgtacgaat
    11881 aaaaaaaata gaggcggaga atacttatcg tatcatccgc ctttgttttt ttgttataaa
    11941 aaacgtcaga ttagttatct gcttacatct tcatccatac gggttctaat gtatttccgt
    12001 ctagatcttg gacttctaat gaaaacattt cttcttcagg cattcccata tctacttcgt
    12061 ggaaagtacc accattttct tttgcaattt gagcaaattt ttttacttca tccgcatttt
    12121 caacactaaa cgaaatcaaa gcaccacttg tttttttatt atcagctatt tctttatctt
    12181 ttataaattt tttataaaaa tcatgagaga gaagcattat ccaaaaagtg tcatcccata
    12241 ccattgaacc agcttcttca gtagaaaatt cttcattttt tttaaaaccc agcttttcat
    12301 aaaaagcaac ggaacgattg acatcagcaa caggaaaatt aacaaaaacc atactattca
    12361 tttgtttcgt ctcctttctg ttttgttcgt ctatcatctc ttatttagga aacgctgtca
    12421 aaaatttaga ttcatatata gaaaccaaaa taaaaatttg catcatcaaa aaagtgaaga
    12481 tgtgatagaa tgaggactgg ttcactttca cttaactaat agatggaatt tctttataat
    12541 aaaaaagtga atttatattg aaaaagaaaa aaacaagtaa agccggggaa tattccggta
    12601 tgaaaggaat ggagagaaca atgaccatcc aatggtttcc gggacatatg gcaaaagccc
    12661 gacgagaagt ttctgaaaaa atgaaatatg tggacatcgt atttgaattg gtagacgcac
    12721 gattaccttt atcttctcgt aatccaatgc tagatcagat cattcagcaa aaacctcgcc
    12781 ttgttttatt gaataaagcg gatctggcag atccacaaca gacaaagctg tggcaagaat
    12841 attttcgtaa acaaggccat cttgcattag ctatcacggc acaagaaagt aaaggaatta
    12901 aaggtctagt acctgcggct aaagaagcat tgaaagaaaa acgggcaaga gatgctgctc
    12961 gggggatcaa gcctcgcgct attcgggcaa tggtcttagg tattccaaat gttgggaaat
    13021 ctacgttgat gaatcgacta gtaggcaaga aaattgcaca gacaggaaat aagcctggcg
    13081 taacaaaagg tcagcagtgg cttcgtttag gtaatgagtt ggaattgtta gacacaccag
    13141 ggattttatg gcccaaattt gaagatgaag aaatcggcaa aaaactagcg ctgacaggcg
    13201 cgatcaaaga ccagcttgtc catttagatg atttagcgat ttacggatta gacttttttg
    13261 cccgatatta ttcaggaaga atcagcgatc gttatggttt atcaatcgag caagaagaaa
    13321 aattggcacc ggaattactg atggatatta cagcaaaacg tgggtataaa gaagactatg
    13381 atcgtggcag cgaattagtc gtgcatgata ttcgtcaagg aaaacttgga cgatacacac
    13441 tggatcgttg cgaagaaatg gagcaaaaaa gtgatgactg aatccatcca aagtatcaaa
    13501 gaacgattga aaagcataca gagaatagat gatcctacac tagaatcatt aagaaatgat
    13561 ccacgcaaag gcgtgcagca agcactggct tcttttgaac gacgattgaa aaaggaagca
    13621 ttaattaagg aaaaatatga agaaatgttt tgctttgaaa agcaagggta cgcacaaggt
    13681 caccaatgga ttgccggcat tgatgaagta ggaagaggac cattagctgg acctgtcgtg
    13741 gcagctgcag ttatcttgcc gaaaaatgag atcatattag ggctgaatga ctccaaacaa
    13801 ttatcagaga aaaagcgaga acttctttat caacaagttc aagaaaaagc cctggcaatc
    13861 gggatcggga tcgttgatca gcagacaatc gatgatgtga atatttatga agcaagtaaa
    13921 ttagcgatga tccaagcagt agaaaaattg tccattgtac caagctattt gttgatcgat
    13981 gcgatgacct tggatttgcc tattcagcag gaaaaaataa tcaaagggga tgcacgatct
    14041 gtgtcgattg ctgctgcaag tatcattgct aaagtatatc gagaccaatt gatgaaagaa
    14101 tatgacgtgc tttatcctgg atatggtttc tcgcataatg caggttatgg aacaaaggaa
    14161 cacttagaag gacttgaacg acaaggaatt acgccaatcc atcgtaaaag ttttgcacct
    14221 gtaaaaaaat atttacaata aaaaacagcc gcttttacgt atcttattag aaagagagac
    14281 gaaaggcggt tttatgatgt atcaaataga agaaaattta ttgaaacttg cttatacaaa
    14341 aggaatcagt agtcaaggaa aatgggcact tgctaactgg atgatgcagt atccttataa
    14401 agaaatcgga tttgaagaca tcattaagat aggtaaaata accaaacacc gggagctgtt
    14461 tcgcaaaagt tggcaggaaa ttcacgctaa ctggggcaaa atccaatcga aacagtcgtt
    14521 tatcacttgc tttgatccca aatatccccc tcagctgctt cacttgacct atccgccaat
    14581 tgtactgttt tataatggtg atctatcttt actttcttgt aacatgttaa gcgttgttgg
    14641 tggaagacac acttctgctt tagccaaaaa aacagtttat tatttactaa aaccagtgat
    14701 agaagctgga tatgtgatcg tcagtggctg cgcgaaaggg atagatacat acggtcacca
    14761 agcagcaatc tctcatggtg gacggacaat cgcagtcatt ggaacaggga tagagcaagt
    14821 ctatcctgct gaaaatcgtg acttgcaaga ggtgattgca aatgatcatc ttcttttgag
    14881 tgaatatcct cctcaatccg gcccgaaaaa gcattgtttt ccaatgagaa atcggattat
    14941 cgcagctttg tctaaaggaa catgtgtctt tgaagccaag aaaaaaagcg gctctctgat
    15001 aacagcacag caagcattgg atcttggaag aacagttttt tctgttccag gaaatatttt
    15061 aacagaacat tctaccggat gtcatcattt gatccaagac ggtgcagttt gcacggtttc
    15121 gggtgaagat atcttggcag aatttaaaga ataacaccat acttttcatt tgcttttctt
    15181 gacaaacgtt ttctgaatgg atatgattag ctacgatttg tatgaatcct cttttaatag
    15241 taggaacacg acaatggaaa ggagtccatt cagtaatggc gtataaatat ttagtgattg
    15301 tagaatcacc tgcaaaagcc aagacaattg agaaatatct tggacgaaac tataaagtaa
    15361 tggccagtgt tggccatata agagatttac cgaaaagtaa aatgggtatc gattttgaaa
    15421 acaattatga accccattat atttctatac gcggaaaagg cgatgtcatc aaaagcctga
    15481 aagccgcagc aaaaaaagct caaaaagttt acttggcaag tgacccggat agagaaggag
    15541 aagcgattgc ttggcattta gcgtacctac ttgggttgga tctgaaagaa aaaaatcggg
    15601 tggtcttcaa tgaaatcaca aaagacgcag tcaaagcagc ttttaaggaa ccaagaacga
    15661 tcgatgtaga tttagtagat gcacagcaag ctcgtcgtac cttagacaga atcgttggtt
    15721 attcgatcag tcctattctc tggcgtaagg tcaagaaagg gttaagtgca ggacgtgtcc
    15781 aatctgtcgc tttaaaaatt attattgacc gtgaaaaaga gatccgagaa tttgttccag
    15841 aagaatattg gagcatcgac ggtaatttta aaaaagctcg caagaaattc aaagcaaatt
    15901 tctggggaat cgacggtaag aaaaagaaat taccagatgc acaaagtgta aaagaagtca
    15961 ctgctagaat tgatggaaca gacttcgaag ttaaaaaagt agaaaagaaa gagcgcaaaa
    16021 gaaaccctgc gaatcctttc actacaagta gcctgcaaca agaagctgcc cgtaagttaa
    16081 actttcgaac aagaaaaacc atgatggtag cacagcaatt atatgaagga atcactttgg
    16141 gtaaacaagg aacagtcggc ttgattacat acatgcgtac tgattctacc cggattgccg
    16201 atacagcaaa agcagaggcc gcagcattta ttgaagatac gtatggaaaa gaattttcta
    16261 gacatgatca ccgaaagatc aaaaatgctc aaggcgcaca agatgcccat gaagctgtgc
    16321 gtccaacgag tgtgcttcgt acaccagatg aactcaaaca atatttagat aaagatcaat
    16381 tgaaacttta tacattgatc tggtcacgtt ttgtggctag tcagatgaca ccagctattt
    16441 tagatacaat gaaagtgaca ttagaacaaa atggtgtcat cttcattgcg aacggttcaa
    16501 aaatcaaatt caaaggattc atgcaagtgt atgtggaagg tagagatgac ggcaaagaag
    16561 agaaagaaaa tattcttcca gaacttgaag aaggcgatgt agtccaatct gttgatattg
    16621 aaccaaaaca acattttact caaccaccag cacgttttag tgaggctacg ttgattcgtg
    16681 cactagaaga aaacggggta gggcgacctt ccacttatgc accaacactt gatacgatcc
    16741 aaagacgcta ctatgtaaaa ttgacacaaa aaagatttga gccgactgaa ctaggagaaa
    16801 ttgtcaattc attaatctgt gaattcttcc ctcaaatcgt cgatatccat ttcacagcag
    16861 aaatggaagg agatttggat aaaattgaag aaggcacgga agcgtgggtc aaagtggttg
    16921 atcgtttcta taaaccgttt gaaaaagaac tgacgaatgc ggaagaaaaa atcgaaaaaa
    16981 ttcaaatcaa agatgaacca gcaggattcg attgtgatgt ctgtggacat ccgatggtga
    17041 taaaattagg gaaatatggg aagttttatg cttgcagtaa ttttcctgat tgtcggaata
    17101 cgaaaccaat cgtaaaagaa atcggtgtga cttgcccagt atgtcatgaa ggacaagtca
    17161 ttgaacgaaa atctaagaaa aacagactat tctatggttg ttcccgtttc ccagaatgtg
    17221 aattcacttc ttgggataaa ccagtgggca gaaattgtcc aaaatgtgac ggatatctgg
    17281 tcgagaagaa agtcaaaggc ggtaaacaag tagtctgtgt aaatggagat tacgaagaag
    17341 acatccaaaa ataatagaaa agaggttctt tcattgaaaa tggtaaatgt tgttggagca
    17401 gggcttgccg gaagtgaagc tgcttggcag atcgcacaag caggagtccc tgtccgttta
    17461 tatgaaatgc gtccagtcaa atcgactgag gcgcatcaca caagtaattt tgctgaacta
    17521 gtatgttcca attcattaag aggaaacagt ttggctaatg cagtagggtt attgaaagaa
    17581 gaaatgcgcc gattgaattc ggtagtaatc acttcggcag atgaaacagc agtgccagct
    17641 ggtggtgcct tagctgttga ccgcgattct ttttctgaaa caattacccg aaaagtcaaa
    17701 gagcatccat tagtaacagt gataaacgaa gaaattactg aaataccgga aggaatcacc
    17761 gtagtagcaa caggaccttt gacttctcat ccattagcag aaagcatcaa agcattcaat
    17821 ggttcagatg gtttttattt ctatgatgca gctgcaccaa tcgtagacaa agctacgatc
    17881 gatatggata aagtatattt gaagtcccgc tatgacaaag gagaagcagc ttacttgaac
    17941 tgtccgatga cagaagagga attcaaagct ttccatgagg cactaatcaa tgccgaagtg
    18001 gcagaactta aatcttttga gaaagaaaaa tattttgaag gatgtatgcc aattgaagta
    18061 atggcacagc gaggattcaa aacgatgctt ttcggaccta tgaaaccagt tggattggaa
    18121 gatcctaaaa ctggcaaacg tccttatgct gttatccagc tgcgtcaaga caatgctgca
    18181 gcttctttat acaacatcgt gggctttcag actcacttga aatggggcga gcaaaaacgt
    18241 gttttccgga tgattcctgg gttagaaaat gctgaattcg ttcgctatgg tgtgatgcac
    18301 cgaaacagct ttatgaattc gccagaattg ctgaaaccga cttaccaatc aacgaaacgc
    18361 gaagatctgt tctttgcagg tcagatgact ggtgtagaag gctatgttga aagtgcagcg
    18421 agcggactac ttgctggaat caacgccgca cgcttagcaa aagaaatgga accagtcgag
    18481 tttccacaag aaacagctat tggaagtatg gcttactaca ttactcatgc ggaaggaaaa
    18541 catttccaac cgatgaatgc caactatggt ctgtttcctg aactgccaga gcgcattcga
    18601 gacaaaaaag caagatatga agcaattgca caacgagctt taaaagctaa tgaggcaata
    18661 aaaacagaat tagaaaaaac tgcaatccca aatgagtaag gaaactccat gaagagggtg
    18721 agacggatag tctcgctctt tttcttgcgt ttttcttaag aatttctcaa acaaaatgtg
    18781 aggaattgcg ccaattgtga acaaacttag aaatattggt taaattctga caatttattt
    18841 gtctttttat aaacgctgtg ctaaattatt ctctgggaca aaaggaaggt gagaaaatga
    18901 cagaagccac gtgggaacaa aaatttttgc gttatttgat tgtcgaaaga ggatattcag
    18961 aaaaaacgaa agaagcatat gaagaagaca ttctccattt caaacatttt ttggaggaat
    19021 ctggagacgc tgatctgctg aaggcggaat attttacggt tcgtgtctat ttgagtgcat
    19081 tagctgatca tcgtcctagc tatagcagaa attctatcag tcgcaagata gccagcctac
    19141 gttcgtttta tcagtatctt ctcaaagaag aagtgataaa agaaaatcca ttttcttacg
    19201 ttcatctcaa aaagaaaaat ttgagactgc cacgtttttt ttatgaaaat gaaatgcaag
    19261 cactttttga cagcgtagca ggagatagtc ctttggattt gaggaaccgc gctttactgg
    19321 aagtccttta cgggtcaggc atccgtttaa gtgagtgtag cagtttgtcg gtatcagaca
    19381 ttgattttga ttcagaggtc atgttgatcc atggtaaagg gaacaaagag agatatgctc
    19441 ctctaggttc ttttgctcaa gatgctctgc aagaatattt cagggaaggc cgccaggtat
    19501 tgatgacaaa atatcacgaa gagcatgata tcgtttttgt gaatcatcat ggaaaaccaa
    19561 tcacgcctac tggaattgaa tatgtcttga atcaaatgat caaaaaaagc agtttggata
    19621 gtgatatcca tcctcacatg ctgcgccata catttgctac tcatttatta aataatgggg
    19681 cagatttgcg gacagtccaa gaattgctag gacatgccaa tttatcgact acccagatct
    19741 atgcccatgt aacaaaagaa agtttacaaa aaaactatcg ttctttccat ccaagagcgt
    19801 aaaaataagg aaaagaacaa atttaggagg aaacaaacat ggtcgaatca ccatttcatt
    19861 caaccactat ctgtgccgtc gaaaaagacg ggaaatttgc tatggctgga gatggccaag
    19921 taacaatggg tgaatctgtt gtcatgaaag gcactgcaaa gaaagtacga cgtatctaca
    19981 atggagaagt tgttgtaggt ttcgccggaa gtgttgcaga tgcgtttact ttagaagaaa
    20041 aatttgaagg caaactaaac gaatataacg ggaatctaca acgcgcagct gtcgaattag
    20101 ctcaagaatg gcggacacag caatctatgc aaaaacttga agcgatgctg atcgtaatga
    20161 atgataaaga aatgcttctt gtttcaggta caggagaagt tatcacacca gatgatggta
    20221 tcttagctat cggatcagga gggaattttg cgttggctgc agcccgagca atgaaaaact
    20281 atgctcaaaa cgacatgagt gcgaaagaaa ttgcagaaaa tgcgttaaat attgccgcag
    20341 atatctgtat ctttactaat cataatatta tcgtagaaga actgtaagag gtgagtagat
    20401 atgtatgaat taaaacaaac accaagacaa atcgtaagtg aattagatga atatatcgta
    20461 ggacagcacg cagcaaaaaa atctgttgcc gttgctttgc gtaaccgcta tcgccgtttg
    20521 cagttagatg aaaaaatgca acaagatatt acaccaaaaa atatgctgat gatcggacct
    20581 acaggggtcg gtaaaacaga aatcgcacga cgtttggcaa aaatcgtcaa tgcaccattt
    20641 gtcaaagtcg aagcaacaaa atttactgaa gtcggttatg tcggaagaga tgtagaatca
    20701 atggttcggg atttagtaga aaatgcgatc caaatcgtag aaaaagagca gtacagccgt
    20761 gtatacacaa gtgctaaaaa aaatgcagaa aaacgtttgg taaaaatctt ggtacctggt
    20821 atcaaaaaag aacagaaaca atccactaat caatttgaac aaatgatgaa tctttttaat
    20881 gctagtcagc aaaataccgc tgaaccgcaa gaagaagtga cagaagatat tcgaatcaat
    20941 cgccgtacag tcttggaaca actacaaaag ggtttactgg atagtcgtga agtaaccatt
    21001 gaagttgaag accaaaagaa acctgcacca atgatgaaca atggattgga gcaaatgggg
    21061 atcgacctaa atgaaactct aggtgctttg acaccgaaga aaaaagtgga acggacggta
    21121 acagtcaaag aagctttaga gttattgatc aaggaagaat cagcaaaatt agtcaaggat
    21181 gctgatatcc atagtgaggc aatcaaatta gcggaagaaa gtggaattat ttttatcgat
    21241 gaaatcgata agatcacttc taaatcacag caatctggag aagtatccag agaaggcgtc
    21301 caaagagaca tattgccaat tgtcgaaggt tcacaagtaa acacaaaata cgggatcatc
    21361 caaacagatc acgtcctatt cattgcttca ggagctttcc atttgtctaa accaagtgat
    21421 ctaattccag aacttcaagg acgcttcccg atacgggtag aattagatga tttgacagct
    21481 gaagattttg tgaagattct gaccgaacca aataatgctt tagtaaaaca atacgtcgcg
    21541 ttgatcggta cagaaaatgt gtcagttacg tttacaaaag aagcaattga acggatcgct
    21601 caaatcgctt ccgatgtcaa ccgtgacaca gataatatcg gcgcacgcag actgcatacc
    21661 attttggaaa aactactaga agatctatta tttgaagcac cagatatgca aatgggagaa
    21721 ataacgatca cagaagcata tgtggatgac aaacttggct caattgcggc aaatgaagat
    21781 ttaagtcgct atattttata aaaaatcgga ggacgacaat gacagacttg ctaacgaaaa
    21841 cccgcaagat aaacacactt ttgcagcaaa agaatacttt tgacatgcaa gcagatttgc
    21901 cttacgataa aatggctgtc acactaggtg gtattcttga cagcaacacc tatatcatag
    21961 gaagtgacgg agtattacta ggttataatg aacgtcacga tgtgaacaat gaacgaatca
    22021 aaacaatgtt tgttgagaaa caatttcctg aatcttatac tgatacagtg gcacagttga
    22081 tgaaaactga agctaatatc ccaattacta gtgatattac tgcatttccg gtagagtcaa
    22141 gagagaaata tccatttggt ctgacgactg tcgttccgat ctttggagct ggcgaacgtt
    22201 tgggtacgat tatcttatct cgtatggaac aatcgtttgc agatgacgat ctagtcttag
    22261 cagaatatgg agctacggtt gtcggtatgc agatccttta tcagaagtct cgaagcatcg
    22321 aagcagatgt acggagtgca acggctgtcc aaatggcaat caacacatta tcttatagcg
    22381 aattgaaggc tgtacaagct atctttgaag cattggatgg agatgaaggt cgtctgactg
    22441 cttctaatat tgccgatagt atcggcatca ctcgttctgt gatcgtcaat gctttacgaa
    22501 aattggaatc agctggaatc attgaatctc gttcgttagg catgaaggga acttatttaa
    22561 aagtattgaa ttcccgtttt aaagacgagt tagcaaaaca cagttattag aagtaagggg
    22621 actggggcag atagaaatgt ttgttccagc cttcccattt taaaaagtaa gtcgaagttg
    22681 gaggaatggc aatgactgtt attattcaaa atgaccagct gatcgccgaa atcgctgaac
    22741 acggtgcgga attgatcagt ctgaaatcaa aagaacatgg tttagagtat atctggcaag
    22801 gtgatccagc gtattggggc agacatgcac cggttttatt cccttttgtt ggacgtttaa
    22861 aagatgatca gtatgtttat caagggaaaa catatcaaat ggggcaacac ggatttgctc
    22921 gggatatgga ttttgaagtc attgaacatg gacaagaaat ggctagtttc atcttaagga
    22981 gtacgccgga gacattagaa aagtatccat ttgattttga attagtgatc agctatgaat
    23041 taggaggaga cggcatcacg gttcattatc aagtggcaaa taccggtgaa aaagaaatgt
    23101 tcttttctat cggtggacat cctgctttca atgtacctct tgaagaagga ttgtcatttg
    23161 aagatttcta tctggcattt tctccattga aatcaagatt acgcctacca ttgaaaggcc
    23221 cattcatcga tatggatcaa aagacgttag gtcagacaaa tacgaatctg gctttgaatc
    23281 gtgaactttt tgagcaagat gccttggttt ttgaaacaag gggtctaaat gcgtacgcca
    23341 ttcgaagtga aaaatcttcc catagcgtaa ctttaagcta taaagatatg ccttatgtag
    23401 ggatctggtc tccttatcca aaagaagcgc ctttcgtttg tatcgaaccg tggtgcggaa
    23461 tcgctgacac ggtgaacagt agtggaaact tgatggaaaa agtagggatc aatcaactag
    23521 gtgcccatga aatcttcaag acaaaatatt ccatcacagt gaagtaagag gttgtgaccg
    23581 agaagttagc agggaacacc gtttaccaag gtgtgtaaaa aagctatcct gtaagtaata
    23641 agggagtgtg acatcg
//
LOCUS       DASHWW010000035        23578 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.035, whole genome shotgun sequence.
ACCESSION   DASHWW010000035 DASHWW010000000
VERSION     DASHWW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.035"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            44..676
                     /locus_tag="U2R64_001620"
     CDS             44..676
                     /locus_tag="U2R64_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEM8918442.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(678..1583)
                     /locus_tag="U2R64_001621"
     CDS             complement(678..1583)
                     /locus_tag="U2R64_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEM8918443.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1668..2327)
                     /locus_tag="U2R64_001622"
     CDS             complement(1668..2327)
                     /locus_tag="U2R64_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEM8918444.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            2643..3587
                     /gene="mvk"
                     /locus_tag="U2R64_001623"
     CDS             2643..3587
                     /gene="mvk"
                     /locus_tag="U2R64_001623"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEM8918445.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3580..4557
                     /gene="mvaD"
                     /locus_tag="U2R64_001624"
     CDS             3580..4557
                     /gene="mvaD"
                     /locus_tag="U2R64_001624"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEM8918446.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4570..5655
                     /locus_tag="U2R64_001625"
     CDS             4570..5655
                     /locus_tag="U2R64_001625"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEM8918447.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5652..6716
                     /locus_tag="U2R64_001626"
     CDS             5652..6716
                     /locus_tag="U2R64_001626"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEM8918448.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6965..7768)
                     /locus_tag="U2R64_001627"
     CDS             complement(6965..7768)
                     /locus_tag="U2R64_001627"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEM8918449.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7788..8630)
                     /gene="kduI"
                     /locus_tag="U2R64_001628"
     CDS             complement(7788..8630)
                     /gene="kduI"
                     /locus_tag="U2R64_001628"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HEM8918450.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(8646..9653)
                     /locus_tag="U2R64_001629"
     CDS             complement(8646..9653)
                     /locus_tag="U2R64_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEM8918451.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(9660..10304)
                     /locus_tag="U2R64_001630"
     CDS             complement(9660..10304)
                     /locus_tag="U2R64_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEM8918452.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(10404..11162)
                     /locus_tag="U2R64_001631"
     CDS             complement(10404..11162)
                     /locus_tag="U2R64_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HEM8918453.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(11289..12440)
                     /gene="fucO"
                     /locus_tag="U2R64_001632"
     CDS             complement(11289..12440)
                     /gene="fucO"
                     /locus_tag="U2R64_001632"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HEM8918454.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(12522..12833)
                     /gene="rhaM"
                     /locus_tag="U2R64_001633"
     CDS             complement(12522..12833)
                     /gene="rhaM"
                     /locus_tag="U2R64_001633"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HEM8918455.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(12835..13680)
                     /gene="rhaD"
                     /locus_tag="U2R64_001634"
     CDS             complement(12835..13680)
                     /gene="rhaD"
                     /locus_tag="U2R64_001634"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HEM8918456.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(13694..14950)
                     /gene="rhaA"
                     /locus_tag="U2R64_001635"
     CDS             complement(13694..14950)
                     /gene="rhaA"
                     /locus_tag="U2R64_001635"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HEM8918457.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(14947..16407)
                     /gene="rhaB"
                     /locus_tag="U2R64_001636"
     CDS             complement(14947..16407)
                     /gene="rhaB"
                     /locus_tag="U2R64_001636"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEM8918458.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            16560..17429
                     /locus_tag="U2R64_001637"
     CDS             16560..17429
                     /locus_tag="U2R64_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HEM8918459.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(17555..18454)
                     /locus_tag="U2R64_001638"
     CDS             complement(17555..18454)
                     /locus_tag="U2R64_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918460.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(18619..19443)
                     /locus_tag="U2R64_001639"
     CDS             complement(18619..19443)
                     /locus_tag="U2R64_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEM8918461.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(19454..20749)
                     /locus_tag="U2R64_001640"
     CDS             complement(19454..20749)
                     /locus_tag="U2R64_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HEM8918462.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(20765..21244)
                     /locus_tag="U2R64_001641"
     CDS             complement(20765..21244)
                     /locus_tag="U2R64_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HEM8918463.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(21250..22278)
                     /locus_tag="U2R64_001642"
     CDS             complement(21250..22278)
                     /locus_tag="U2R64_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HEM8918464.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(22295..23401)
                     /locus_tag="U2R64_001643"
     CDS             complement(22295..23401)
                     /locus_tag="U2R64_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEM8918465.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6779 a         5200 c         4239 g         7360 t
ORIGIN      
        1 tcccgcttct ttgctatact aaagaaaaac gaggtgaacc cacatgaaaa aaatcgaacc
       61 tattccacct tctcttcctc ttcttacaaa gggagagttt tatttagaag atgaggagat
      121 cttctctggt cttctgatca acgggggtga ccaaagctat ctcgatgcca aaaatatggt
      181 attaagagag agtcatatcc aaaaacttac gatgcaaaaa acagttttac gtcattttga
      241 atgcagtaat gtcatttttg aaaaatgtga tttttccaat ctggagtgga ttggtggcag
      301 tttccaccaa gtcgtgtttc atcaatgtaa attaacaggt acgaattttg ccgaaagtta
      361 tcttcgagac tgtactttca ctgattgtat tgcttcgatg gcttccttta gtagtacaaa
      421 cttgaaagct gtctccttcg atcattgtca attagaagac agcgaatttt atgaggtcac
      481 ttggaaaaac ctttttttgt ctgacaatca gttgaccggt tcgaactggt ttcgaacttc
      541 tctgaaggga ttagacttta cgactaattt cttcacagca atcgctttat ctcaagattc
      601 tttggcggga ctaatcgtca accaagagca agcacttgtg atcgcccaag cccttggttt
      661 gcagatcaaa gactagatca acgaatccgc cgccacagtg caataagcat ccaaatagat
      721 aagaccaaac tgatgatcaa ggcgattccc catccgaaaa cggaatgggt aaagggtaac
      781 tggagattca ttccgaagaa tcctgtcaca atagttggaa cggtcaagat cagcgaccag
      841 accgtcaaaa atttcatcgt gtcattcaag ttgttattca gcaaattatt ataagtgcca
      901 gagagctggt ctaaaatctg cgaagctaag ttcgtcattt caactgcttg tcgtgcttcg
      961 atcagcgcat cgtccaactc ttctttttcc ttttctgaca acttgcgata aatagccaat
     1021 gccttgattt gttctaaaag tactacattt tgttttgttc ctgtaactaa gtaaaccaaa
     1081 ccgatctcta aatctgaaag ttgcagcaga ttcttgttcg ttgttttttc tcttaatttc
     1141 agattaagcc gctgacgttc actattcact tcctcgatta aaggaaaaaa ggaatcagaa
     1201 atcaaaaaca atgtacgaaa caataaactg tatacactca tgtctggcat tcgttccaaa
     1261 agcgatcgaa ttagtcgaat cacgtactcg gtattcggcg tggtaaatgt aaacaaaccg
     1321 tcttctttta aaataaaagc gataggacta gtttcataat gattatcgac tttttgctgg
     1381 tgcggaacat ttgatacaag cagtaacgct tcatcaaaag aatcgtactc tacgcgcgcc
     1441 cgttcatttt tatctagaga ataagtcagc atctcgtcac taatgccata ttcttctttt
     1501 aagtttttaa cagctagcac atcgttttgc tgtacattga tccaaaaatt acggtcttga
     1561 ttaaaatagt gtttttcccg catactctat cctcctgaca tttgtttcca gtataaagaa
     1621 aaaagtcgct caaataaagg tttacccttt atttgagcaa ctgtaaatca aatggctact
     1681 ttggtttggc gaatctctgc taatttttct tcgatcattt tcaagacttc ttcttttgct
     1741 tgaggatctt ccacaaaatt atagcggtct ccatcgattt ggatttttgg actttctttg
     1801 tattcttcat accattgatc gtaacgtctg ttcaattctt tgtaataatc gtatagactt
     1861 ggatcaaagg acaattgttc atacgaacga ccacgttttt cgatacgctc caacatcgta
     1921 tcaaaagata cacgaatatg aactaataaa tccggatgtt ttttatgggc agcataggga
     1981 agttcttcca tcatgttttc cagcagttca tcatacacac gaacttctgt ttctgttgct
     2041 cttcctagat ctgcatttag atggaaaagc agtgaatctt cataaatcga acggtccaat
     2101 acattattgt catctttcat tgcttgtttg atgcttgcaa aacgtttatt caaaaaataa
     2161 atttgcagca aaaaagcata ctgttcaggg tttgcataaa ataagggcaa gacttcatta
     2221 tcatcaatcg attcataaaa tgcctgacta tcaaagtgtt cagccatcat ttctgttaaa
     2281 cttgattttc cggcaccaat tgtacctgct aaaacgatca cgctcattta cctccagctc
     2341 acttcatcac taaatattgt gtttaactcc aaccttttta aatatacccc caatatctag
     2401 tagtgtcaat tgtatttttt tctagtcaaa gaagaaaaaa agtcaaaaaa ttcttaagaa
     2461 aaaagtgttt tttctttaga aaacgtattc ttagttttac ttctgagatg gttttagtaa
     2521 aataaaggag gaatgttttt tgagaccctt agtggacaaa aaaattcgtg aagcagcgca
     2581 actcgttttg ggcgctttat tttttgctta aaaatcactt ttacgtgaga aggagttaga
     2641 ttatggcaaa ctatggccaa ggagaatcaa gcggaaagat catattgatg ggcgagcacg
     2701 cggttgttta tggagaacca gcgattgcct ttcctttcta tgcaacaaaa gtcaccgcat
     2761 tccttgaaga gctggatgca atggacgatc aactggtttc ttcctactat tcaggaaatt
     2821 tagccgaagc tcctcatgca ttaaaaaata tcaaaaaatt attcattcac ttaaaaaaac
     2881 agcatgacat ccaaaaaaac ttgcaactga ccattgaaag cacgattcct gctgaacgtg
     2941 gaatgggatc aagcgctgca gtcgccacag cagtcactcg tgctttttat gattacttag
     3001 catttccttt gtctcgtgaa atactattag aaaatgtcca gctttcggaa aaaatcgccc
     3061 acggtaatcc tagtggaatc gatgcagccg ctactagcag cttgcagccg atttatttta
     3121 caaaagggca tcctttcgac tacttttctt tgaacatcga tgcttttttg attgtcgctg
     3181 atacaggaat caaaggacaa acaagagaag ccgtcaaaga tgtcgctcac ctctttgaaa
     3241 cccagcctca tgaaactgga caaatgatcc aaaaattagg atacttgacg aagcaagcaa
     3301 aacaagcaat cattgaaaat tcaccagaaa cgttggcaca gacaatggat gaatcacaat
     3361 cacttctgga aaagctgaca atcagcaatg attttcttaa tctattgatc caaacagcaa
     3421 aagataccgg ggcattgggt gccaaattaa ctggcggtgg acgcggtggc tgtatgattg
     3481 cattagcaca aacaaaaaca aaagcccaag aaatcagtca agcacttgaa gatgcgggtg
     3541 ctgctgaaac ttggatacaa ggattaggag tacataccta tgtttaaagg caaagcacgc
     3601 gcatatacca acattgctct aatcaaatat tggggtaaga aaaatgaaga actcatcctt
     3661 ccaatgaaca acagcctttc gttaacattg gatgcatttt atacagagac agaagtcatc
     3721 ttttctgata gctatatggt agatgaattt tatctagatg gcaccttgca agacgaaaaa
     3781 gcaacaaaaa aagtcagtca gtttcttgac ctttttcgta aagaagccgg cctctcacta
     3841 aaagcttcag taatcagtca gaatttcgtt cctaccgcag ctggattagc ctcctctgcc
     3901 agcgggctag ctgctttagc aggcgcttgc aatactgctc ttaagcttgg attagatgat
     3961 ctctctcttt caagatttgc tcgacgcggg tctggttcag cttgccgaag tattttcggt
     4021 ggtttcgtcg aatgggaaaa aggccatgac gacttaagtt cttacgctaa gccagtccct
     4081 tccgattctt tcgaagacga tttagcaatg gttttcgttt tgatcaacga ccagaaaaaa
     4141 gaagtgtcca gcagaaatgg gatgcgtcgg acagtcgaaa catccagttt ttatcaaggc
     4201 tggttagatt ccgttgaagg ggatctatat caattgaaac aagcaatcaa aacaaaagat
     4261 ttccaacttc tcggagaaac gatggaaaga aacggactaa aaatgcatgg aacgacttta
     4321 gctgcccagc ctccattcac ttactggtct cctgacagct taaaagcgat ggatgcggtg
     4381 cgacaattga gaaagcaagg cattccatgc tactttacga tggatgctgg ccctaatgtc
     4441 aaagttttag tggaaaacag ccatttatct gaggtacaag aaacatttac caaattattt
     4501 agcaaagaac aagtaattac tgcacatgct ggtccaggaa ttgcgattat tgaataaagg
     4561 gagattttta tgattgaagt atctgcacca ggcaaactct atattgccgg agaatatgca
     4621 gttgttgaaa caggccatcc agcagttatc gctgcagtcg atcaattcgt gacagtcact
     4681 gtagaatctg cacgaaaagt cggaagtatc caatctgcac aatatagtgg gatgcctgta
     4741 cgttggacaa gacgcaacgg agaattagtt ttagatattc gggaaaatcc ttttcattat
     4801 atccttgctg ctattcgctt gactgaaaag tatgcacaag aaaaaaacat tcttttatcc
     4861 ttttatgatc tgaaagtaac aagtgagtta gacagttcaa atggccggaa atatggattg
     4921 ggttctagcg gtgccgtgac cgttgcaacg gtcaaagcct tgaatgtttt ttacgcgttg
     4981 aatttatctc agttggagat tttcaagatt gcagcactag ccaatttagc agttcaagat
     5041 aatggttcct gcggcgacat cgctgctagc tgttatggtg gctggatcgc tttctcaacc
     5101 ttcgaccatc cttggctcca agaacaagaa actcagcatt ctatcagtga gttacttgcc
     5161 ctggattggc caggtctatc cattgagcca ttgattgctc ctgaagattt acgtttattg
     5221 attggttgga cgggtagccc tgcctctact tctgatttgg tcgatcaagt tcaccgttcg
     5281 agagaagata aaatggtggc ttatcagctt ttcttaaaaa atagtacaga atgtgtcaac
     5341 gaaatgatca aagggtttaa agaaaataat gtaacgttga tccaacagat gattcgaaaa
     5401 aaccgacaat tactgcatga tttatctgca atcactgggg tcgtcatcga aacgcctgct
     5461 ttgaacaaat tgtgtaattt agctgaacag tatgaaggag ccgcaaaatc ttctggtgca
     5521 ggtgggggcg attgcggaat cgtaattgtt gaccagaaat ctggcattct tcctttaatg
     5581 agtgcatggg aaaaagcaga aatcactcca ctgccgttac atgtctatag cgatcaaaga
     5641 aaggaaaacc gatgaatcga aaagacgaac atgtttcact agctaaagcc tttcatgata
     5701 aacaaaaaaa cgaatttgac ttcgtacgga tcatccataa ccctttgccg caaatagcag
     5761 tttctgatgt cgatctaagt acacaggcag ttgggtttac actaagcagc ccattttata
     5821 tcaatgcgat gactggcgga agcgaaaaaa caaaaaaaat caaccaagat cttgcaatcg
     5881 tcgcaagaga agcagatttg atgattgcca ctggttcagt cagcgctgcc ttgaaagtcc
     5941 cttctttagc cgatacttat acgattatgc gacaagaata tcctcacggg aaaatcattg
     6001 ccaacatcgg tgcagggact tctgtcgaaa gagccaaaga agctatccga ttgtttcacg
     6061 cagatgcctt acagattcat ttgaatgcac ctcaagagtt ggttatgcct gagggagacc
     6121 gtgattttac caattggaaa gtacttattc aagaaactca aacagccatt gacgtccccc
     6181 tcatcgtaaa agaagtcggt tttggcatga caagagaaac gctcaatgat ctagctgctt
     6241 taggagttca tacagttgat atcagcggtc gaagcggaac aagcttcacc cagatcgaaa
     6301 acgcccgtcg ctccaagcgg gaactgagtt atttagctga ctgggggcaa tcgacagtct
     6361 cttcattgct tgaagcaaat gaagcagaca cttctatgga aatcctagcc tccggaggta
     6421 tccgcaatgc ctatgacata tttaaagccc tttgtctcgg cgcaaatgcc gtgggtactt
     6481 caggaaccgt actgacgcat ctgatgaatc acggcgtaga agaaactatt atactgatga
     6541 agcaatggca agaagagctt cgtctgcttt atactatggt cggcgcaacg aataccgcgg
     6601 ccctacacca acaatctctg atcttttccg gaccagtgaa ggattggtgc gaagcaagag
     6661 ggatcgactt agtgaagtat ggaagacgca cagaaaagag cgtgggacaa aagtaaagaa
     6721 cacttttgtc tcacgctcta aacacgtaca aacggcggaa gtaaaagcaa ctccttcgga
     6781 aataagctga aattcacaaa aatttgaaaa gcaattttcg tgaattcctt cttatttctt
     6841 ggagttaaat gcttctgtcc cagcctcttt tttcgaataa atgatgttta atcagctgtc
     6901 cttcggtatt cgttcaatcc gctgatttca caacctctcc actaaacagt gtactaaagc
     6961 tcttttaagg ttgttttccg atataggcaa gtatgcctcc gtccacatac aagacatggc
     7021 cgttaacgaa atcagatgcg ctagaagcca agaagacaga tggtccagcc aaatcgattg
     7081 gctcgcccca gcgtgctgct ggcgtacgtc caacgataaa ttgatcgaat ggatgacgtt
     7141 caccgttttc ttgtgtttcg cgtaatggag cagtttgcgg tgtagcaata taacctggtc
     7201 caattccatt acattggata ttgtattgac cgtattcaga agcgatgttt ttcgtcagca
     7261 tttttaatcc gccttttgcc gcagcataag cactgaccgt ttcgcgtcct aattcactca
     7321 tcatggagca gatattgatg attttaccgc cgcctttttc gatcatatcc ggaataactg
     7381 cttttgaaac gatgaatggg gcatttaaat ccacgtcgat tacttggcgg aagtctgccg
     7441 catccatttc gatcatcggt gtccgtttga tgatccctgc attgttgact agaatatcaa
     7501 ctgaacctac atcttctttg atctgttgaa ccatcgcttg aaccgcttct tcatcggtca
     7561 catcgcagac ataacctttt gcatcgatgc ctgcttcttt ataatgcgct ataccttcat
     7621 caactgattc ttgattcaag ttattaaata cgatttttgc tcctgctgta gctaaagagc
     7681 gtgcaatctc aaatccaata ccatagacag caccggtgac taatgctact tttccatcta
     7741 aacgaaacat atccatacta aattccatca ttttctctcc cttatgctta ttttaattga
     7801 tccatttgca ccatatccat gtctgtatag gtgatatttt ctccgcacat tgcccagatg
     7861 aatgagtaat tgcttgtacc tacacctgaa tggatcgacc agcttggcga aataatggct
     7921 tgttcattgt ctacaactaa atgttttgtt tcatctggtt tgcccatcat gtggaacaca
     7981 cgtgtatctt cattggcata atcaaagtag acataagctt ccatacgacg ttcatgtgta
     8041 tgacaaggca tcgtattcca agcgcttcct ggttctaaaa tcgtataacc catttgtaat
     8101 tgacagcttt cgcatacatt tggatggatg tattggtaga ttttacgttc attcagtgtc
     8161 aggccttcac cagtctccat tggttttact tggtcgatac tgatttttac atttggatat
     8221 ttatgatgag ctggaacaga actaatatag aatttagctg ggttttcagc atcttgagaa
     8281 gaaaatacaa catgtcgtgt ttcttttccg atatagtatc cgtcttgttt tttcatttct
     8341 tctttttgcc catcgatctc gatgaatcct ggtccaccga tattgatcac acctagttca
     8401 cgacgctcta agaagtaatc aacacctagt tctttgtcta atgtgatttc taattctttt
     8461 tcagtaggtg tcactccacc aaagatcatt cgatcgttgt gcgtataagt caaactgatt
     8521 ttccctggtt caaatacctt ttctactaaa aattcttttc tcaattgttc cgttgaataa
     8581 tgacggatat cttctggact gtgtgtataa cgtgtttcca tttcttgcat tttcttctac
     8641 tccttctatc gaatgatttt tccagagccg catgctaaaa attgtgcgac ttcttcttga
     8701 ctaaattggt tgcagtcccc atggatcgta tgcttcaagg cagaagctgc cgtagcaaaa
     8761 tcaatgattt cttgcggaga catattggat aaaatcccat ggagcacgcc acctgcaaaa
     8821 gcatctccgc cacctactcg atccacgatt ggggtgattc tatggacttg ggattccaca
     8881 tattcatggt tcatccacaa tgtccccttc aattcatttt cacttgctga atgaacggta
     8941 cgcttggtcg aataaaacac ctgaatattc gggaactttt cctgcatttt ttgataataa
     9001 taaattagag gttgttcttc tgcttctggc gctttctcga tacctaacaa ataaagagca
     9061 tccatttttc cagctgagca gatatctact aaaggtaaaa gctgatggat tacttcgctg
     9121 gcttcttgct gtgtccataa ttttccacga tagttgatat cgaagctgat caggcagcca
     9181 gctttttttg cagcttctat cacctgtttc gtcatttttt gccatttttt agacaaagct
     9241 ggggtgattc ctgaaacatg aaatatatct attccttgga ataactcctc tagcgaccat
     9301 tccaaatgat ccatttcagc aaaacttgat ccggcacgat catagatcac tgaggcggcg
     9361 cgttcgccac taccagtttc catataataa gtacctagtc ttgatccacc agataatacc
     9421 tgtttcgtat ctactccata acattgcaag tgctttttga ctgcttttcc caatgcgtta
     9481 tcaggtactt ttgtagcaaa aatcgcttca tgtccgtaat tagctaaaga aattgctacg
     9541 tttgcttccc ctccgccata atgggcagcg aatcgttcac ttgaatcgat acgggttccc
     9601 tgctctgtgg acaatcgcaa catgatttct ccgagtgtca ctacttttcc cataagcagc
     9661 tacctcttga tttctttcat ttttgctgca tactgttgcg cgacttccgt tactttgtca
     9721 aaatctcctg tagctgcggg tgctaaaagg ttcccaccta ctccgactgt tacgacacca
     9781 gcatcgaacc actctttcat attgtccaga ctcacaccgc cagttggcat gatattgact
     9841 tgaggcatcg gcgccttgaa ggcagaaatg atacttggtc cataagcgct tccaggaaat
     9901 agtttgacga tatctacccc gcttttcagc gctgttttga tctcggtaat agtcatacat
     9961 cctggtaagt aaggaatttg atacagattg cacatctctg ccgtttcttg atcaaaggaa
    10021 gggctaacaa tatactctgc gccagctaag atagccaagc gagctgtgac agcgtctaat
    10081 actgtgcctg cgccaatcac tatttctggt tggtctttgt agaatgacaa aagttctttg
    10141 attacttgat ctgcttgagg gactgtaaaa gtcaactcaa taccagttag accacctttg
    10201 atgattgcgt ggcaagcatt caaagcttct tctttgcttt ttccgcgtac caccgcaatc
    10261 actccggcgt ttttcaatcg agataaaata tcaatttttt tcatcttctc cacctatttc
    10321 ctatttagaa attttatttt ataacttgga aatctatacc catattatac ggcagaaaag
    10381 aaaaattgca aacgcttttt tcattatttt tgaattcttt gctcgatttc gctttttgtt
    10441 tgcttgaggg cactgattat ttgttctttt gtctcatctg ttaaacgata tttcggcata
    10501 cttacactaa atgcaccaat gatttgttcg tttttcacga ttgaggctcc tatacaaaaa
    10561 atatcacgtt cgatttcttc atcgtcaaat gcgatgtggg tttcttttac cgtttggatt
    10621 tcctttttca accgtaatgc attggtgatc gtatattctg tgtaagggat caacggatgc
    10681 ttttcaagat aatcagtgta ctgctcttca ctgaattctg ctaatacggc tttgcccatc
    10741 gcagaattgt ataatggtcg ggtgattccg atttttgaag acatgcggat cgtttgatgt
    10801 tttggatcta gtttgttcac gtacaagatc tcattgttgt ccaatacccc taagtggata
    10861 gtctcatcga tcttttgctg cagctgttct aaaaacggta aagtcaactc taccaaatcg
    10921 atttgttcaa tgtttttatt cgcgtagcga ataagctttg cacctaaacg atagtttttc
    10981 tctgaatttt tatttacgta gccgatcatc aacaaagtat ctagtatttt caagactgta
    11041 gaagaggtca ttcccacacc ctttgcgatc gtctgcaaag agacatcttg gttttccgct
    11101 aaatagtcta gtattttaga ggctttgatc aatacagttc cataaggctt tttattttcc
    11161 atataatatt ctcctatttc tttataagaa aaattatagc ggaaatacca tcaatttaaa
    11221 agagatatcc agatataaac taccatttct ctttacaggc aatttaatgt tgaagatccg
    11281 cttcgttttt acatcaaact ttgatataaa gcaatgattt cttctactgt cgtttctctt
    11341 ggatttcctg gtgtgcatac atctcgcaaa gcatcttctg caattgctgg aatatctgct
    11401 tcttttacac ctaattcaga aatggtttct gggattccaa ccgctttgct caaccgatcg
    11461 atctcaccac aagccgcttc tcttacatct tctaaagaca tttcagctgc tcctttaatc
    11521 cctagaacaa gagcgatctc acggtacttt tctccagtat attctttgtt atatttcatg
    11581 acagttggca aaagtgctgc acacgctacg ccatgaggaa tgttgtacca tgcacttaac
    11641 gggtgagcca tcccgtgtac cagtcctaaa ccgacatttg agaagcccat tcccgcaata
    11701 tactgtccta atgccatttt ttctcgccca ttttgatcgc catctacaga agcttccaaa
    11761 gaatggccga tgatttcgat tgcttttaaa tgcagcatat cagtcatttc ccaagcgcct
    11821 tttgtgataa acccttcaat agcatgcgtc atagcatcca tacctgttga tgcagccaat
    11881 tttttcggca ttcccatcat catatcgctg tcgatgaacg cgacgattgg gatatcatga
    11941 ggatcaacac aaacaaattt tcggtgattt acttcatctg tgatgacgta gttgatcgtt
    12001 acttctgctg ctgttccaga agtcgttggt atagctaata taggtaaaca tggatttttc
    12061 gtatcagcaa caccttctaa actaatgacg tctgaaaact ctggattcgt caaaataatc
    12121 ccaatggctt ttgccgtatc gattggcgaa cctccaccga ttgcgatcaa acagtctgcc
    12181 tctgcctctt taacaaaagc cactccatct tttacatttt ggatcgttgg attaggtacg
    12241 atcccgtcgt ataaagcata agcgattgct gctttatcta gaagttctgt tacttttgtt
    12301 gctataccgt gctcgatcaa tcctttgtca gtaatgacag ctgctttgcc gaatcctcgc
    12361 tgctgaaatt cagggacgat cgactcaatc gctccttttc caaaatacga tgtttcattt
    12421 aaaatcattc gattactcat tttctattcc tcctaatttg tattattttt cacaataaaa
    12481 acgaaagaac cccaagcaac cggttgccca gttgcttgtt gctacagttc aaagactggc
    12541 atcaattccc aactgactgg agaggcatct ggatttgtct ccatgatatc ttccatgtac
    12601 ttccaccatt tttgattgat agatgtattt gccatttttt cccataactt ttcatcttcg
    12661 atcactaagt aaccaaataa caaacttgta ctcggatcaa gatagatcga atagtcgatg
    12721 accccgtgtt cacgaagtgc tgtacgcatt tctggccaaa gttcatcatg tctttttttg
    12781 tattcttctt gtttttctgg gtaaactttc atgcaaaaag cttttttcac catgtcagac
    12841 acctgctttc gtatgaactt cctccaaata acctgctttt ggagtgacac caaacgcatc
    12901 tgctaaatgc cacaggtttt cgtccgtgat tgtttgcaag attggtcctt gcgctttgac
    12961 gtacgtatag acttctgctg ccttttctgc tgtctcgatc aaaccaaaga cttcatccat
    13021 gtcttttcct gacccgtaga ttccatgttg tggccataaa accaatcgag tttctttcat
    13081 tttttcagct gttgcttccc caatctcatt tgttcccgga accatccacg gaatgatgga
    13141 aattccttct ggaaaaacaa ctaagcattc cgtacacatt tgccatagcg tacgactaaa
    13201 ggaacgttcg tctaattcat gcgtaaaact catcgctaat agatgactag catggcaatg
    13261 cataacgatc cgattatctg ggtctacttc taaacgggcg atatgactca tgaaatgact
    13321 tggcaactcg cttgtaggaa ggcattcgtt ttccagcccc cacaaaagtt ccagtgtttt
    13381 gccatcttca gcaactcgaa cgattccaag attctcggca ggttcgctcg ctacattttt
    13441 aaaatatctt cctgaaccag ttacaataaa atagcatcct gctaaacggc tggcatcaaa
    13501 aatcatcgag atgcggcgga tcactttttc aggatccaag aacggtgtga tctcttcttc
    13561 ttttagtaaa taagaaatat tcccgccatt tctttcatcc catcccaagc gataaagatt
    13621 cgacgtcgtt tcgatcattt ctttcacata aggcgcttgt aaaatatcta tttttttcaa
    13681 tatagccaca ctcctatttt cttaattcca acacgtcttt ttgatattcc tggacttctt
    13741 ccagccaatc caaaccaact ggaacttgat ttttgtaaca gaaataattc catacatcgg
    13801 catacgggaa atctttcaat tcttccgtat aagccattct tgaagtaaag tcaaaagcca
    13861 gctccatttc tttcaatcgc tcaactggtt ccagcatagc tttcagcagt gctttttgtg
    13921 tatttctcgt accgatgacc caagcagcga tacggttgat cgttgcatca aagaaatcca
    13981 gaccgatatt tgttttttcc aacaattcgt tacggactaa ttctttagcg atttcctgca
    14041 attcatcatc catcaaaacc acatggtctg aatcccaacg cactggacgg gaaacatgca
    14101 acatgattcc tttgctgaat aaagctaatg aagataattt attggaaatc acttctgttg
    14161 gatgaaaatg tccagcatct agacaaacaa gtttgtcacg agtcaacccg taacccatat
    14221 aaaattcatg ggaaccgact gtataagctt cagcgcctaa accaaatagt ttgctttcta
    14281 ctgcatcttg tacataccgt tcatctaact cttctgtaaa aatttcatcg agtgattcca
    14341 ttaaacgttc ccgtggggta aaacgatcaa tcggattatc tttcatccca tcaggtaccc
    14401 aaaagttatt gatacttgtt tgcccagttt ctttcccaaa gtactccgcg attttgcggc
    14461 ttcttttccc gtgttcgatc cagtattcac gaacttcttt atctggatga gccaatgtaa
    14521 agccgtcttt catcattgga tgcgaaaaga aagtcggatt gaagtcaaga ccgatttctt
    14581 ctttttttgc ccactctacc catttttcaa aatgtttcgg ctcaatttca tttagatcga
    14641 cagattcttc tgtatccaaa tagatagcat gaaggttcaa tttgtgtttg cccggtatca
    14701 acgaataagc cttctccaga tcttgtctaa gctcttcagg tgttcgtgcg gctcctggaa
    14761 aattccctgt cgccatgatt ccaccggtca attcgccatc cggtgtcaag aaacctttga
    14821 catcatctcc ttgccagcaa tgcatagaaa ttttgatgtc ctgtatcttt tctagtacag
    14881 catctgtatc tacaccgata gttgcatatt tttcttttgc ttgttcgtaa tttctttcaa
    14941 tcgtgttcat acgattactc ctttgatttt attcacgtac cattccatcg tgttttgctt
    15001 attttcatct gggtaaaaag tttcacatgg aaacgactgt ttgattacat ttcttgcttg
    15061 ttctatattc gaaaactgac ctgtactgag catttgcatg gcaacattcc cgattgctgt
    15121 ggcttcacta ggtcctgctt ctacaatgat tccggcataa tctgctgtca attgattcag
    15181 tagacgatta ttcgatccgc cccctacgat gtgcagcttt tccaatttcg ttccagttaa
    15241 gtgttctact ttgatcagct cttgtgcgta acaaagagca agattatcat acacacaacg
    15301 agcgatagct cccgatgaga cagggactgg ctgctctgtt tcaaaacagt attgctgaat
    15361 ctcttctatc atatttgggg gattcaaaaa tcgagggtca ttgatttcca tcacttgctg
    15421 cagcggtttt tcttttgcag caagctctgc caattccgca taactgtact cgtactcttg
    15481 cattcgggca acttcctgga tcaaccacat ccccatgatg tttttcaaaa aacgcaccgt
    15541 gttatgggca ccccattcat tcgtataatt ttcagaaaaa gcattgcgag aaacattggc
    15601 gatctttgtt tcaatcccta aaagcgacca tgtcccactg ctgatataac cccaacgttc
    15661 tccttgacct ggcgttccta atacagctga cgccgtatca tgacttgcta ctgtgataaa
    15721 ggtcacatct ggcaaatcat attttgaaaa ttgttctttt tgcagatctc ctagtatcgt
    15781 tcccggctct gtcaatggtg gaaataattc cttcgagaca ccgatttttt caagaagttc
    15841 tatttcccat tcttttgtcc ctgcattcag cagctgcata gtagatgcat tagttttctc
    15901 cgtcaccatg ttaccagtaa agacataccc taaataatca ggtatcagta acaatttatg
    15961 tgcttttgcc aaattttctt tttcttcagc aaacaattgg aacaaggtat tgaaaggctg
    16021 gatctgaatc cctgtctgct catacaactt atctagagaa tagatttcag aaaactgttc
    16081 tactgctcca ttggtacgct tgtcccgata agcaatcgga tcatttatcc gatccccttg
    16141 ttcatcaatc agacagtaat cgactgccca tgtatcgatc cccgcaaaaa ggcgatcaat
    16201 ccctgtctgc tttaattttt caaatccaat caaaatctct ttgataagat aatcgatctt
    16261 ccagcgatcg tgaccgtctt tgttccgaaa gccgtttttg aaccggtgta cttcttccaa
    16321 gatcaaagaa ccttttgcat ccctcgtact tttcattagt cgtccgcttg atgcaccgat
    16381 atcgatggca acaaatgttg gattcatttc tccacctctt ttactttatt gttgattagc
    16441 actttattaa taaagcgtta tcatttatta acaatgctat cataatacag aatcttatat
    16501 tttgcttcac actattttgg tatataattg cattatcttg acaagttggg agtgtttaca
    16561 tggattactg ggaaaaagcc aaccactcat ggtcggaaga ctcaaaaaga gtgatcttga
    16621 cgcctacaca aagaagcagg aatttatttt tttatatcca agaaatcggt tacttcaaag
    16681 caccaatccc ttactatact gaacgagcac atttaccttc ttacttgata aagtttactt
    16741 tgtctggcaa aggttcgctt acatataatg ataatcagca acagctaaaa gctggagact
    16801 tattttttat tgactgccaa gaatatcagc gttatcaaac gatcagcgaa gaaccatggg
    16861 aaatggattg gatccatttg aatggtcaga acgtccaatc attttatcag gagttcacaa
    16921 aagacggcca taacaccttc cattcaacag gggatccatc agaaaacaag atccaccatt
    16981 tgatcacaga attgatccac atgcaacaag gcacgaatgc ccgtaccgat ttccagtcct
    17041 ctgtagctat ccacgagttg ctgaatgaac tgattttgca aaagtatcag ctagatttcg
    17101 aagaagagga tattcccgcc tacgtttaca aactgaagca atacttagac gaacatttca
    17161 aagaaacgat tacacttgat caattagaac aacaattctt attgaataaa tatcagctga
    17221 gcaaagattt ttccaaattt atcggttctc caccaatcga ttatttgatc agcaaaaaac
    17281 tttcttacgc taaagacctt cttcggtata cagaatttac ggttcgaatg atttccgaag
    17341 aaatagggat tgagaatttt gcttacttta gccgcctgtt caaagcaaaa acaggactat
    17401 cgccgagaga ctttcgtaaa ttcagctgat tcatataata tgtacgtcat tttttcaaaa
    17461 tattttgaaa tatatagata aaaataaaat aaccgcagtt tctgcttcta tgtaaacaac
    17521 agcagctact gcggttattt tttagtgatc attctcattg ttcatcttca aaatgttcat
    17581 aatgaaccaa ctgtttctgt gtatcacgtt tcaaaaattc tttaggcgtt atgccgaact
    17641 ctctcttgaa tgctttcaga aaatgcggat aagaagaaaa accactttta ctatatacag
    17701 cactagagct gcggtattct cgcaacaagt gcttggcata gatcagcttt ttcttcatta
    17761 catactgatg aaacgtaaat ccagtgtact ttttaaattc tcgtgtgata tggtatttgc
    17821 tgacaaaaaa ctgcttttcc atttcctcta aagaaagcgg atgagataaa ttttttgaga
    17881 tatattgtaa catttgttcc acacgctcat taggaactac agcattctgt tcttgcgcac
    17941 tctcttcttt ttgtacaact tgattgagaa aaatcaagta ttctaccaga gcttgttcat
    18001 attttatgtc ttcaccgtaa atttttttat caggaggatg gtcgataaat gataattttt
    18061 gcttcaatac ttcctgttct atttgcaata cacgactcct cttctctccc attggttgaa
    18121 agcaagccga tagattagac catggcgtgg aacgactttc tagaaaagaa ggggtgacaa
    18181 agatatagac acgctcgaat acatctgaag attggcggac gatacgatgc aaatcattgg
    18241 aatggatgag cagcacactt cctgctttga tcgtaaattg tcgtccgttc aaataaaaag
    18301 tcgcttctcc ctttaatgta gcatggatct catagaaatc atgatgatga tagatcgttt
    18361 tattttggct gacgacatct ttgacatgat agatttcata ctgatcagaa accatcgtat
    18421 tgacttgttc accgctgatt ttcttttgga gcatgtgccg cacctccttt tgttcactta
    18481 tgcacaattt tattatacca cgttttttgt aatcaaaaag agctgctttt atatactctt
    18541 ataaaaaaga agagacgtgg catcttctag ccccgccccc tccattctaa atattagtta
    18601 accaacgtct tctttacatt attcaagaag acttcttcca taacgaatcc catcatcttt
    18661 tgtttcttca agaaccacat acaggtacgg acgattcttc atgatgattt ctttgatttt
    18721 tgtgtactcg atcacaccgt ctcccaaatt taccggcacg attttttcct gttcgacacg
    18781 aaaatctttc aaatgaaccg cacatatctt ttcaccaaaa cgttcaaaag cttcttctac
    18841 caattggact tgttcttgat aatcactact tgtgatcaaa ttggtcggat ctaaaatgat
    18901 tcctagatag tccgaatcta ctgcttggat cagctgctct acccttgcta aagaatacac
    18961 cggatgattc aaacctggtt ctatccccac catcatttgg tatttttctc cagcttttac
    19021 caagcgacgg ataacggaca cagcttcagc aaatgcttca tctgtgaaat tttcttccgt
    19081 atattggatt tccggcaaaa cacatccagt ttccgaagca accatcgacg caccaaagga
    19141 agaagcatag cgaagatact gctcgaactt tgtcagcaac tcttgtcgta tcgttaaatc
    19201 tggatgaatc atattgatat agcaacttaa aattcctacg gtcacttctt gcttttctaa
    19261 aactcgtttg acataatttc ccatcccaga attgatctca tttgcgccag aaggtatttc
    19321 aggaaacgaa agacctaagg cgagctgcag tgtatgaatc ccttgttctt ttgttttttc
    19381 tgcaagatct tctatcgttt ggacttcgga aagatcatgt cctctaattg taatgttcaa
    19441 cataactatt ctcctaactc agcatattgg gtagccacat gacgatttgc gggaagtaag
    19501 taatcaaaaa caagacgact aagataaccc cataaaaagg aagaagcggt ttcagcattg
    19561 cctctgcttt tacgcctcct acacttgcac cgacatatag tcctgtacct actggcggcg
    19621 tgatggagcc tacacacaga ttcatgattg aaaacaaccc gtaatgtaca ggatcaaccc
    19681 ctacacttgt gacgattggt aaaaatattg gtgtaaaaat caagatagca ggcgccacat
    19741 ccataaacat acccaccagt aataacacaa gattgactaa taacagaata ataaatttat
    19801 tatccgttac gcccataatc aacgaactaa ttgcctgagg aataccggta aacgccatgg
    19861 cgaaagacat catggaagaa gtagccaata agaacatgat cgtccctgac attgctactg
    19921 attgaaacaa catattaggt atatctttta gttttaccgt tttatagtaa aacatagcaa
    19981 tcaacaggga gtaaatgaca gctatcgctg aagcttctac tgctgtaaat atccccgtca
    20041 agataccacc gataatgatg acaatcaata gaaggctagg aatcgcctct tttattattt
    20101 ttccagcatg agccatctgt cctttttcga caacagggta tttattcttt ttagcaacga
    20161 tgaatgctac tagcatgatt cctagcgccc acaaagcgcc tacgagataa cctcccataa
    20221 acaaagcaga gatcgaagca ccaccagcaa caagtgaata catgataaaa gcagtacttg
    20281 gaggaatgac catacctgtc ggagctgacg cgatattgac cgctgtcgca aacttccggt
    20341 catatccttc ttccacttgc tgagggatca acactccgcc aatcgcggta gaagcggcaa
    20401 tggccgagct agagatggaa ccaaataaag cattccctaa cacattcgta tgagccaaag
    20461 cccccggcac gcgcccgacg aacaacatcg caaaatccac tagtttctta gctatccctc
    20521 cattattcat gataatgccc gagagaacga aaaacggaat agcgatcagc gaaaaactat
    20581 tgatacttcc caccattttt tgagctgaac taaaagcaga aacatcaaac ggtataacta
    20641 acaataaagt catcatcgat gagaatgcaa tacttatagc aatcggcatc cctaatacaa
    20701 gcaacacaac aaatacaaaa aataacacta atccggcttc tattgccatt ttattcctcc
    20761 atttttatat tttttcttga attgctggct tgttgcttaa tgtatcgatt agattgatca
    20821 ggctatagat aatgatgagt acccccgata caggtactga cagataaaca tatcccatag
    20881 gaatacttaa agaaggcgag atctgcccca ttgtcaatgt gacagcattc catccgccat
    20941 acaccatgat catcgcagca aataccagaa ataaactttg aacaacaact tctaaaattt
    21001 tacttttttt gccagttaat ttttcactta aaaccgttac ggctaaatgt gctttttgtc
    21061 ccacaacata cgcggaagac aacatggcaa accagacaag accgaatcga acaagctctt
    21121 ccgtgaccgt atttggattt cctaaaaccg ttctggaaaa tacttgccat aaaacaacag
    21181 cgaccatccc aacaagcaaa acagctccca ggatctctaa taccttgttt aaaatcattt
    21241 tcatcacagc tacgctcctt gctcttggat cttttgataa aggtctttgt aggtaggatc
    21301 gtttttgaat atatcatgaa gtggggcaac tgcctctcga aacggtgtat tatctacatc
    21361 attgaattgg actccatgtt cttcttgtgc taaagctttt tcttcttcaa ttgcttttgc
    21421 aaaagcttca atttcaaaaa ccgttgattc tttcgctgct tcttcaatgg ctttttcctg
    21481 ctcatcagtt agctgttctt tgatggcatc attcatgatg atgatatctg gcacacgtgt
    21541 atgctcatca taggaatagt atttagccac accaccatgt ccagctgtat acaagacaaa
    21601 ttcattgttt tctgatccgt tgatcaaatt ggattgaaga gacgtgtaca cttcatcact
    21661 tcccataggt acgggcgaac cgcctaaaag ctctaccatt ttgatagcgg tttcgctttg
    21721 catcacacgg atcttctttc ccttcaaatc ttccggcgta tggatcggac cgtctaccat
    21781 ataaaagctg cgctgaccag aatcataata ggtcaatccg gtaaatccta aatttttggt
    21841 cgattggtag attggctcca ttatttcttc attatccatc accttaaaga aatgttcttc
    21901 atcattgaat agataaggaa ctgaaaaaat cgaataatct ttagagaaac tttccaacgc
    21961 tgaggcactt acttttgtga aatctactgc tcctgactgt gtcaattcga tcagttcacg
    22021 ttctccaccc agttgtccat ctgggaaata ctggatctgt acggaaccat ctgttttttc
    22081 ttttactaaa cgcccaaatt cattcattgc atcaattact ggctggctgt tgcttgcata
    22141 agcaaagcgc aaggtaacta tctcatttac atctgcatct gcgacagttg ccacactaga
    22201 attatttccg cagccgctta gacctagcag acctaggcta agcgaacttg ctgcaaacag
    22261 cagtgatgtt tttttcatat gggtttcctt tcttttaaca ataagagacg agcaattctg
    22321 tcaaacaaag caccgttaac gactgtccat aaggcattgc tgtgattccg atattccgat
    22381 aaaaatctaa actgtccccc attcctgtcc cgattgaaac gttttgaact tctccttttt
    22441 catcgatttg ttcaagcaat ccttggatag cacgataagc gacttcttta tattcttgtg
    22501 gtaaataacg tttatggacc gctttcaaaa taccgtaagc aaatcctgca gttgcagaag
    22561 attctacgta agaagaagga tcatccaaca acgtatgcca taaaccgctt tcagactgat
    22621 aagtttttaa tgcacgcact tgtgcttcaa gtgtttcgat caataatttg cgcaatgcat
    22681 cttctttcga taattctaag atttcaatga tctctggaat agcaatcgtc aaccagcagt
    22741 ttccacgagc ccaaaatgct tcggcatagt tatgatttcc ttcaaacgtc cagccgtgat
    22801 accacaatcc tgttcgttta tccatcaagt atttgatatg gatcataaac tggtaacgag
    22861 cttcttctaa atattctggg cgattcaaca gtttcccgat ttttgccaaa ggaagcactg
    22921 tcatcatcaa tgtatcgtcc cacaactgat tcttattttc cggtccatat gtggcatgct
    22981 gtaacccgtc ttcatttgtc cgaggcatgt cattcatgac ccattctgcc cattgttcta
    23041 aataaggcaa atagcgtgaa tctttcgtgt cttcatacaa gtaagccata gtcaatagcg
    23101 gtgccattgt attgacgttt ttgggcggag cgccttcttc catacgatcc tcaaaccatt
    23161 cattgaccac ttgataagcg cgaggatttt ttgtcatctg gtaattttta taaataccat
    23221 atagaccgac accttgtggc caattccaca ctgtccagct tttgtcatct actttcagtc
    23281 catcaaagtc caacaaaaat tcaccattat cgtctttgat cgttgtcagg ttttcaacga
    23341 gcaggtcaat tttttctttc actaattctt taggtacaaa aatctcttct ttaataatca
    23401 tctttacgcc acttttttaa acgctttcat tttatatcct taatatagca gtaataccgt
    23461 ccactataaa tatcgctttt tgaacaaaaa ctgtctaaaa ttgacctaaa tgttaaataa
    23521 caaaagtaac tttcagttac ttggaaatta aaaaaagaac ttggagaaac aacgtttt
//
LOCUS       DASHWW010000036        23571 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.036, whole genome shotgun sequence.
ACCESSION   DASHWW010000036 DASHWW010000000
VERSION     DASHWW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.036"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="U2R64_001644"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="U2R64_001644"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEM8918466.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="U2R64_001645"
     CDS             complement(1172..1867)
                     /locus_tag="U2R64_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEM8918467.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="U2R64_001646"
     CDS             complement(1880..2596)
                     /locus_tag="U2R64_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEM8918468.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="U2R64_001647"
     CDS             2926..3531
                     /locus_tag="U2R64_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HEM8918469.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="U2R64_001648"
     CDS             3856..4179
                     /locus_tag="U2R64_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEM8918470.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="U2R64_001649"
     CDS             4361..5731
                     /locus_tag="U2R64_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEM8918471.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="U2R64_001650"
     CDS             complement(5861..7162)
                     /locus_tag="U2R64_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEM8918472.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9350)
                     /locus_tag="U2R64_001651"
     CDS             complement(7392..9350)
                     /locus_tag="U2R64_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEM8918473.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="U2R64_001652"
     CDS             complement(9527..9793)
                     /locus_tag="U2R64_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8918474.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="U2R64_001653"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="U2R64_001653"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEM8918475.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="U2R64_001654"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="U2R64_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEM8918476.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="U2R64_001655"
     CDS             13137..13700
                     /locus_tag="U2R64_001655"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEM8918477.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="U2R64_001656"
     CDS             complement(13953..14474)
                     /locus_tag="U2R64_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEM8918478.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="U2R64_001657"
     CDS             complement(14477..15319)
                     /locus_tag="U2R64_001657"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEM8918479.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="U2R64_001658"
     CDS             complement(15312..16037)
                     /locus_tag="U2R64_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HEM8918480.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="U2R64_001659"
     CDS             16213..16509
                     /locus_tag="U2R64_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918481.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="U2R64_001660"
     CDS             17077..18669
                     /locus_tag="U2R64_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8918482.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="U2R64_001661"
     CDS             18682..19422
                     /locus_tag="U2R64_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8918483.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="U2R64_001662"
     CDS             19590..20939
                     /locus_tag="U2R64_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8918484.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="U2R64_001663"
     CDS             complement(21067..21657)
                     /locus_tag="U2R64_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEM8918485.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="U2R64_001664"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="U2R64_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEM8918486.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6750 a         4746 c         4490 g         7585 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa caccgtttat
    23281 tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag aaatattttg tgaaaatggc
    23341 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctggcttttg aacaccgttt
    23401 attgagcgtc tataaactga cctgagtatt agagaaacaa aacggcaaag tagctccata
    23461 tactttgccg ttttgttttg aactaatacc gaagagaagc tgatcaaaca acatttcttt
    23521 tataatatag attttagaca tatatatgat ataaaaatag ttttcgcaaa a
//
LOCUS       DASHWW010000037        23145 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.037, whole genome shotgun sequence.
ACCESSION   DASHWW010000037 DASHWW010000000
VERSION     DASHWW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.037"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     misc_feature    111..236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            280..804
                     /gene="infC"
                     /locus_tag="U2R64_001665"
     CDS             280..804
                     /gene="infC"
                     /locus_tag="U2R64_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEM8918487.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            876..1076
                     /gene="rpmI"
                     /locus_tag="U2R64_001666"
     CDS             876..1076
                     /gene="rpmI"
                     /locus_tag="U2R64_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEM8918488.1"
                     /translation="MPKKKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1129..1488
                     /gene="rplT"
                     /locus_tag="U2R64_001667"
     CDS             1129..1488
                     /gene="rplT"
                     /locus_tag="U2R64_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEM8918489.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1740..3047
                     /locus_tag="U2R64_001668"
     CDS             1740..3047
                     /locus_tag="U2R64_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HEM8918490.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3124..5253
                     /locus_tag="U2R64_001669"
     CDS             3124..5253
                     /locus_tag="U2R64_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HEM8918491.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5228..5917
                     /locus_tag="U2R64_001670"
     CDS             5228..5917
                     /locus_tag="U2R64_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918492.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6325..7011)
                     /locus_tag="U2R64_001671"
     CDS             complement(6325..7011)
                     /locus_tag="U2R64_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8918493.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7147..7341)
                     /locus_tag="U2R64_001672"
     CDS             complement(7147..7341)
                     /locus_tag="U2R64_001672"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918494.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7391..7831)
                     /locus_tag="U2R64_001673"
     CDS             complement(7391..7831)
                     /locus_tag="U2R64_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HEM8918495.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(7835..8680)
                     /locus_tag="U2R64_001674"
     CDS             complement(7835..8680)
                     /locus_tag="U2R64_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEM8918496.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8829..10247
                     /gene="pepV"
                     /locus_tag="U2R64_001675"
     CDS             8829..10247
                     /gene="pepV"
                     /locus_tag="U2R64_001675"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEM8918497.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10304..11251)
                     /locus_tag="U2R64_001676"
     CDS             complement(10304..11251)
                     /locus_tag="U2R64_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8918498.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11474..11824)
                     /locus_tag="U2R64_001677"
     CDS             complement(11474..11824)
                     /locus_tag="U2R64_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEM8918499.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12024..13103
                     /gene="pepA"
                     /locus_tag="U2R64_001678"
     CDS             12024..13103
                     /gene="pepA"
                     /locus_tag="U2R64_001678"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEM8918500.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13247..13567
                     /locus_tag="U2R64_001679"
     CDS             13247..13567
                     /locus_tag="U2R64_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEM8918501.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13589..14053
                     /locus_tag="U2R64_001680"
     CDS             13589..14053
                     /locus_tag="U2R64_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8918502.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14258..14863
                     /locus_tag="U2R64_001681"
     CDS             14258..14863
                     /locus_tag="U2R64_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HEM8918503.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(14902..16191)
                     /locus_tag="U2R64_001682"
     CDS             complement(14902..16191)
                     /locus_tag="U2R64_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEM8918504.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            16619..17098
                     /gene="rlmH"
                     /locus_tag="U2R64_001683"
     CDS             16619..17098
                     /gene="rlmH"
                     /locus_tag="U2R64_001683"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEM8918505.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            17183..17692
                     /locus_tag="U2R64_001684"
     CDS             17183..17692
                     /locus_tag="U2R64_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HEM8918506.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            17792..18442
                     /locus_tag="U2R64_001685"
     CDS             17792..18442
                     /locus_tag="U2R64_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918507.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            18893..19831
                     /locus_tag="U2R64_001686"
     CDS             18893..19831
                     /locus_tag="U2R64_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEM8918508.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            19844..20896
                     /locus_tag="U2R64_001687"
     CDS             19844..20896
                     /locus_tag="U2R64_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8918509.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            21162..21797
                     /locus_tag="U2R64_001688"
     CDS             21162..21797
                     /locus_tag="U2R64_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEM8918510.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            21988..22779
                     /gene="msrA"
                     /locus_tag="U2R64_001689"
     CDS             21988..22779
                     /gene="msrA"
                     /locus_tag="U2R64_001689"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEM8918511.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT         7378 a         4067 c         4789 g         6911 t
ORIGIN      
        1 ggaatcactg ctagaaagtc tgctaatcta atcattttca gaaaaggaag acaaactgta
       61 tgaaaaacat tgacaaaaag attagttttt gctatactat gatggttgag aaataaaagc
      121 agaagcaccc gcttctcgcc ttagttgata atgtcactgg gctagatagt tttcactggt
      181 tctattaggt gaagtacgcg cgggttctgt aagagaactc gtttttttat tgccgtttat
      241 tcggtaagct tttctttctc tcataatatt tggaggtgaa tgaccatagc aaaggatatg
      301 atggttaacg acggcattcg tgcacgagag ttacgattga tcggttcaga tggtgagcaa
      361 ttaggagtta agacaaaagc agaagcattg aatattgcag aacaagcaaa cttggatctt
      421 gtgttagttg cccctggtgc gaaaccacca gttgcgcgaa tcatggacta cggtaaatac
      481 cgtttcgaac aacaaaagaa agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta
      541 aaagaagttc gcttaagtcc tacgatcgac ttgaatgact tcaatacaaa acttcgtaat
      601 gcacgtaagt tcttggaaaa gggcgataaa gtgaaagctt ctatccgttt caaaggccgt
      661 gccattaccc ataaagaaat tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg
      721 gatattgcaa cagtggaaca aaaagcgaaa atggacggac gcagcatgtt cttgacgctg
      781 gcaccgaaaa acgacagtaa gtaatttgaa tgactaactg gctgttggac agccgatagt
      841 cggataacga aagattttga ggaggaaata tagtcatgcc aaaaaaaaaa acacaccgcg
      901 gatcagcaaa acgtttcaaa cgtactggta aaggcggatt gaaacgcttc cgcgcgttta
      961 caagtcaccg tttccacggc aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca
     1021 tggtttctag tggcgacttc aaacgtattc gccaacaact agcaaaaatg aaataagaag
     1081 tacaaataac agaatctgaa gatttatttt tattaggagg aattatacat ggcacgtgtt
     1141 aaaggtggaa cagtaactcg taaacgtcgt aaaagagtgc taaaattagc aaaaggttac
     1201 tacggttcaa aacacacttt atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac
     1261 tacgcatatc gcgatcgtcg tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt
     1321 atcaacgcag cagctcgtat gaatggcttg agctactcaa aattaatgca cggtttgaaa
     1381 gttgctgaaa tcgacatcaa ccgtaaaatg ttagctgact tggctgttaa cgatgcagca
     1441 gcatttactg cattggctga ccaagcaaaa gaagctttgg ctaaataagc taaacaatta
     1501 taaagaggaa agaagataac gaaaagttat gttctttcct ctttttttat ttacaatcct
     1561 ccatcaaatg aaacaggaca ataacgtata agtctaaaat agcataatta aggtttttta
     1621 attgaaaact gaacatttat ggtcaccctt taatgaaagc gctaactaca taagttagaa
     1681 tgagtttgac tgatatatta gtttgcttat cagaaaaaca aaatggacgg aggaataaca
     1741 tgagtgatat tattattggt attttgttag ttatctcatt ctttttcatg gtctggtact
     1801 gtgtaaaagg ctacaacttg atggtcggct ttgccatcat ggctactgta tggatgggat
     1861 tagcgctagt cggaaacacg ttttcaccaa acccggcgat ggaagggcaa ggagtaattg
     1921 atgtgttgac gcatatctat acgacggggc cagctgagta cgccaaatcg atcttggtaa
     1981 atgtcttctt tggtgccttt ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc
     2041 tgattcgaaa ggtagttgaa cttggagggg acaagccaag aatcacgatg agcttactat
     2101 gtattgtaac cgctgttata ttcatgtcga tgacaggaat cggaccagtg atttctattg
     2161 cagttattgt gttgccaatc ttgatgtcat taggtatttc agtaccggtt gcactgttct
     2221 catttatggg ctcgattatg gctggaatct ttgctaatat cgtcaatttc aaacaatatc
     2281 aaacgattta tgctggtttc aatccagcgg ctgaaagcta tacttataat gactatttcc
     2341 aaattggtat gattgggatg attgtaagct tagttgtggt actaacggtc gctaatatat
     2401 caatgaacaa aaagaaacgc tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg
     2461 caccaatgat ctcatggtta gccgtattat taccagtttt aggggtcgtt cttttagatc
     2521 ttccaatcat cttaggtttt attctagcag gtatctgggc attgctgttt actggaaaat
     2581 tgcgcggagg ttataaagaa atctgtcgtc agtttgcgaa attatttaca gatggcgcag
     2641 tagatgttgc accaatggtt ggtttcttga tgaccttagc gatgttcaat aattcagctg
     2701 cgtatgcttc tccttatttt tcagctattt ttggagattg gataccgcaa tcaccattag
     2761 tcttggcaat cgtatttgct atattgacac cactaggatt tttccgcggt ccaatgaatc
     2821 tagtcggttc aggctcagct attttagctg tcgtattagc tgttaatcca acgatgtcgc
     2881 cagccttttt gttcccgtta tttgcaatca caacgattgc tcctcagcat ttagatatta
     2941 cacaatcttg ggttgcttgg ggattaggtt atacaaaagt aacttctcga gaatatatga
     3001 agaaatccat cccaactggt tggatcatcg gagcgatctt tgcctgatca cgttcttatt
     3061 gtacgggaac gcctagtaaa caaaacgtcg ataaaaacga ttagatgaat ggaggaaaag
     3121 aaaatgaaac gttttgtgcg aatgggaatt gatgttggcg gtacacatac gaaagcagtc
     3181 gcaatcgata atgcgacgca cgaaatcatc ggaaaatctt cagtgaaaac aacccacgat
     3241 gatgtccgtg gagtagccgc aggtgtcgtt cagtcttttc aaaattgttt gcgggaaaat
     3301 aatatcagtc cagaagatgt tgtgtttgtt gcacattcta ccacacaagc gactaatgca
     3361 ctgattgaag gagacgtagc aaaagtcggc gtaatcggga tggcaaaagg tggattagaa
     3421 ggttttttag caaaacaaca aactagattg aacgatatcg atttagggaa taagaaaaaa
     3481 atagagattg tcaatgcatt cttacctgtc aaacacttaa atgtagaccg tgtttcagaa
     3541 acgatttctt ctttagaaag agaaagagcg gaggtcttgg tttcttctat ggcatttgga
     3601 gtagataatg gggaaccaga acgagttgtt tatgaagcag catcggtaaa atcgatccct
     3661 acaacgatgg cttctgacat cacaaaatta tatggattga caagaagaac tcggacagca
     3721 gcaatcaatg catctatttt accaaaaatg ctagatacgg caacctctac agaagattcc
     3781 gtacgagaag caggggtcaa tgtttctttg atgattatgc gcggagacgg cggagtaatg
     3841 gaaatcaatg aaatgaaaaa acgacctgtt ttaaccatgc tttccggtcc agcagcatca
     3901 gtcatgggct ctttgatgta cttgagagcg tctaatggtg tttattttga agtaggcgga
     3961 acaacaacca atatcggggt cattaaaaat ggacgtccag caatcgatta ttcaattgta
     4021 ggtggccacc caacatatat ctcttcatta gatgttcggg ttctaggtgt ggcaggcggt
     4081 tcgatggtac gggctaatca gtcaggaatc atcgatgtcg gtccacgttc tgcacatatt
     4141 gccggtctag attatgcagt atttacggag acagaaaaaa tcaaaggtcc taaggttgaa
     4201 tttttctctc ctaaagaagg agaccctgct gattacgtca aggtagtgat ggaagacgga
     4261 gaagaagtga ctattacaaa tacatgtgca gccaatgtcc ttggattagt gcaagaagaa
     4321 catttttctt atggaaatgt cccatctgca cgaaaagcca tccaagcatt agctgattat
     4381 tgtcatacga cggttgaaga catcgcagaa cagatcatgg aaaaatccta tgctaagatt
     4441 gaaccggtga ttttagaatt ggcagacaag tatcacttgg agaaagatca gatttctctt
     4501 gtaggtgtag ggggcggcgc tgcctcattg attacttact ttagtaataa aatgggtgtg
     4561 aaatattcga ttcctgaaaa cgccgaagtg atttcttcta ttggtgtagc acttgcaatg
     4621 gtccgagatg ttgtagaacg tatcatccct tcgccaagta aagaagatat acgatcgttg
     4681 aaaaatgaag cgatgaataa agcgattgaa tcaggcgcta caccagaatc gatcgaagtc
     4741 cacgtagaaa tcgatccaca gacttcaaaa gtaacggcta tcgctactgg ttctacggaa
     4801 gtgaaagcaa ccgatctaac caaggagatc acaacagaag aagcactaga gcttgctgca
     4861 gaggatatgc gattaaataa aaatgaagtt tgcttattgg aaaatacacc tttcttttat
     4921 gtatgcggcg aacagaatcg ttcaaaaaat gctggaagtc ttcggatcat cgatcaaaaa
     4981 ggatttatca aggtccaacg tggacatgct tcatgtatga aaacaactgc agccaattat
     5041 atgacagctg tcgaacaact ttgggaagat atggcagttt atcaaactga attgattgcc
     5101 cgaccagaat tttatctctg cttaggagca agagtctctg attttacagc gacggatctg
     5161 gaacaactac agcttttgat ggatctggaa gtatctacta tggaaccgga ggaagaagtg
     5221 atcgtcgttg ccggaaatat caaacaaaca taagttagaa gagttactaa acgaattaca
     5281 acagatcccc gaagaaattt ggggattcta ccagtttcgg cgagatttat tttggaaaaa
     5341 gattcctttg tccaagcaga aaattcttat acaacaatca atcgattgtg gtatcgaaac
     5401 ggcatgtagc atcaaaaaaa agtacccttt tgccgatgta ggagaaattt gtgaacaaat
     5461 ggctgttcca atcgtttcct gtgaatcaga gcaaataaac gaacgaatca cttttgcaac
     5521 ttatgcagaa gatgaaggga ttcgattgat gacggagccg ttagaaaaat taaaatgttc
     5581 aggactagct tcgatctcta aagaaacagc gcaagctttg attattggac atgaactatt
     5641 tcaccacatc gaagcttctg ttaagggaat ttatacgcaa agcgaaaaaa ttgtgctgtg
     5701 gcggttgcct ttttatacac atcaatcaaa cattcgtgca ttgagcgaga tagcagcgat
     5761 gagtttttca aaagagatga atcaaagcga tttttcgcct tatgtattag aggcagtctt
     5821 actttggcca tataatgaaa ttcgtagcca agggatctta gaagaaataa aaaaaataga
     5881 aaaaagatgt acggagtatg atttagatta caaataaaga gactgtgaca aaagtcgtgt
     5941 cacagtcctt tttttccgaa taaacgatgt tctcctgtca actcctcggt cacaagtcaa
     6001 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagatgaa
     6061 cggcaggctc acgacctctt ggaaaacggt gttcaaaagc ttgcatctgc ggtaataagt
     6121 ccagccaagt taaaaacata agaagctatt tttacttggc tgttcttatt acttgatgca
     6181 gggcagcttt ttcacaacct ctcaataaac ggtgtgcaat cagctgaccc tcggtattag
     6241 ctcaaaaaaa acggcaaaat atgaggaact attttgccgt ttctttctct aatactcagg
     6301 tcaaaacgct gattccaaaa cctcttattt gatgggtctg tcctgaatat cttcaaaata
     6361 atcggggtaa ttatgaatca cgtattcttg ctcctcgata atcatatgta aatgcatcgt
     6421 gcaaagaaat ccgacttcat caaagttatg atcaatcatt gattgaagca ttgtctgatg
     6481 ttcatctaat actcgacccc agtctaattc tgaaatcgtc aaacgtaacc atctgaaacg
     6541 gttcaagtgc gtactataac tttctagcca atcccaaatt tctcgttttc cagcaatttc
     6601 ataacaagtt cggtgaaaat cagtatccaa atcaaaaaaa gcttttttat tttgagcgat
     6661 tactgcctga tcggtttgtt ctagtatttt ttctagttta gcttgatctt gcttggtcat
     6721 tttcgcactg cattcttgca ggatcggttt ttccaacttt tcccgcgtat aacgggctaa
     6781 tgaagcagat cggatatcga tttttgaaac ataagtgccg gactgtggaa tggtttttac
     6841 aagctcttga ttgcgcagtt ggatcagtgc ttctcgaatc ggtgtacgcc cgatagctag
     6901 ttgttcttct aacactttat cggagatttt acttccaggt gctaactcgg aataaatgat
     6961 ttgtttacgt atagattcat aagcttgctg ttgcaaatta ttgataacca tttaaccttc
     7021 ctttctatgc agatataatc tattataaca taaatcgctt acaaatcgtg tgggcataaa
     7081 aacacagtct gcaaaaaaag ccctgatagg catgcctatt agagcctcga aaagaaaaat
     7141 attgaatcaa tctggtcgta cctcttgtat cggtttgaca cgaccgccga ttcttttagc
     7201 aaaagcttcg gattcttttt tgtctttgaa aatgagcaga ttgtctaagt ttttttcccg
     7261 agtgcgacag ccagttttat cgatgtaacc gtgcattact ttaacgacat acatggggat
     7321 cacctgcttt tttcttttca ttatacgaac tactcgacac aatacaagaa aaatgcttag
     7381 acggtcttta ttaagaattt acatcatcca aagaagcgta cgcttggaat aactgatcta
     7441 actccggatt gactttgctc agcttcacta atcgttgcga atcagaaagt aaaaaacagt
     7501 gtttactact gccagtagtt tttaattttt tgtcttcagt tcccacaatt tcgtagctaa
     7561 aatccaaccg tgtccccgta tacttttgga tagttggatg gatgctcact ttttctccgt
     7621 aatggatcat ttctttatag ctgcaattta cttccagaac ggggatgatg atcccagatt
     7681 cttcgatttt tttataggga aaccctagat gtaccaataa ggctacccga gcctcttcaa
     7741 accagcggat ataattgctg tgatgaataa tccccatttg atctgtttca taataaaaag
     7801 gttctcgcac ataacctgta aatttctcca tgactcatgc ctcgttttcc attgattttt
     7861 tacaaaaata attcatccat ttcggaagtg cttcgctgat ttgtgtcggc aaaacaatat
     7921 attgttcttt tgccagctgg tctccaatga aactatgaag ataaatagct gctgcaatcg
     7981 tttggtcatt ttgaggaaac tgggctaaaa atcctgtgat catcccagct aaagtgtcac
     8041 ccatgccgcc cgttgccata gcagcagaac ctaaaggatt ggtgtagaag tgctggtgac
     8101 cataaatttt tgtctcatga cttttcaaaa cgagcacagc accgatttcc tgttgcttct
     8161 ttttgttttc tttatcccgt tgttcttgta tcggtagaga actcaaccgt tgccactcca
     8221 tttgatgagg tgtaagtaca gtttgttcgg gatagggtag caaaagatga ttagcagcaa
     8281 gtaaacttaa agcagagcca tcaatcacca gccattgttc ttttgattgg ttttctagta
     8341 cttgtttgaa acgttccaaa ctcttagaag aagtacccaa tccgggacca atcaagagta
     8401 catctgcttg ctttattacg gaaagaaact ggtcagtatc cgtccaaact acaatcattg
     8461 cttctggcag atgactgtga agagcactcc gatttttttc atcagttact acagtcgtga
     8521 gacccgctcc gctgtgtacg gcagctaaag cactcataat gattgctccg ccatattgtt
     8581 cattgccgcc aatcaaaacg atacgtccaa atgttccttt atgtgaaatt tttggacgag
     8641 gtgtgatgat tcttttcact agttgttcgt ttatcagcat ctaaaaacct ccttttactc
     8701 attatagcgt atattttttt tagagaaaaa cagataagaa aaggaattgt cagatttttt
     8761 gaactatttt tttctgtaat ttgtggtatc atgaacacga agacttaaat aagtggagga
     8821 ttaactttat gacaattgat tggcaaaaag aagtagaagc acgtaaagaa gacttgcttg
     8881 aagacttgaa aaatctttta cgtgtcaaca gcgagcgcga tgactcaaaa gtaacaccag
     8941 atgcaccatt tggacctgga cctcgcgacg cattgaaaca tatgttagct tatggcgaac
     9001 gtgatggatt taaagtaaaa aatgtcgata actatgcagg gcatattgat cttggcgaag
     9061 gagacgaaac gctagggata tttggacaca tggatgtcgt tcctgcagga gatggctggg
     9121 acacagatcc ttatgaacca gtaatcaagg atggaaagat ctttgcacgc ggatcaagcg
     9181 atgacaaagg tccaagtatg gcagcttact atgcgatgaa gatcattaaa gaacttgact
     9241 tgaaactatc aaaaaaagtt cgcttcgtag tcggcagcga tgaagaaagc ggctggggcg
     9301 atatggctta ttatttcgaa catgaagaag aaccagattt tggtttctca ccagatgctg
     9361 aattcccaat catcaatggt gaaaaaggaa atgtttcttt agctttacgc ttcaaaggcg
     9421 acaatgcagg agattatgtc ttgaaatctt ttgtttccgg acttcgcgaa aatatggtgc
     9481 caggaacagc aactgcagca cttcaagtac caagtgcaga tgcagctatc gcgatggaag
     9541 aagcatttta ccaattcatc gaagcaaatc cagtaagcgg aacgattgaa gcggacaata
     9601 cgtatgtaaa aatcgaatta gttggtaaag gcgcacatgg tgcaagccca caatctggta
     9661 tcaatgcagg ttctttcttg gcattgttct tagataacta tgaattccta ggatctgcta
     9721 aacaatttat ccatgtagca gctgcttatg tccatgaaga tttttatgga gaaaaactag
     9781 gagtcgctta tgaagatgaa aaaatgggca aattgacaat gaatgctgga ctatttgctt
     9841 ttgaagaaaa tggtacagag gaagcgaact tcatcaatat gaatttccgt tttccaaaag
     9901 gtgtaacagt agacggattg caaagtgaca tcgaacaaac agtggggcaa gaaggcgcaa
     9961 cagttactcg aggtgctcgc gtaatggaac cacattacgt accaatggat gatccattgg
    10021 tggctacatt attgcaagtc tatgaagacc acactggaga aaaaggctac gaacaaatca
    10081 tcggtggcgg aacttacgga cgtttgttga aacgtggcgt tgcttatgga gcgatgttcc
    10141 caggatatac tgatacaatg catcaagcaa acgaatttat gagtcttgat gacttgttca
    10201 gagcaacagc aatctatgca gatgccatct atcgtttggc gaaataatta attaaaaaga
    10261 ggatcaagaa ttgcaaatta tttttgcagt cttgatcctt tttttacttt ctactgtggt
    10321 attcatgata aacatgatat agattcaatt catattcttt cttagcgttc gtgacgactg
    10381 tatccaaaat caaccctgtt actaatgaaa gaagtgctaa agtcatcaat ccagtactta
    10441 aaatcgcaga agggatgcgt gtaataaagc ttgtcagcat atattcgcga atcacaggaa
    10501 tccccgtgac caatccaaat aaaaagaaga agatggtcca aatcccaaag aaaagcaaag
    10561 gcttataatc tttaaacatt ttaataatca tcatgatcac tttgaatccg tcagagaatg
    10621 tattcaattt tgattcgctg ccttcaggac gatcacgata atcgattggg atttcaacga
    10681 acttgaattt tttatctaaa gcatggatcg tcaattccgt ttcgatttga aaaccagaac
    10741 tcataatagg aaaacttttg acaaagatac gattgaatcc tcgatagccg gtcatgacat
    10801 caagaatttt tgttttatac attctagtaa ttgtatttct aacaaggtta tttccaaaat
    10861 cgtggaaagg tctcttattc tcatcaaagt aggttccatt tgataggcga tcaccaatga
    10921 ccatatctgc ttcaccagaa cgtaatttct cgagcaaacc atgtacagct tctgcaggat
    10981 aagtatcatc gccatctacc attaaataat agtcggcatc gatatcaaag aacatttggc
    11041 ggatcacatt tccttttcct tgacgaggtt ctttttttac gattgctcca ccttgaacgg
    11101 ccaattcgta tgttcgatcg gtcgaattat tatcatagac ataaatatct gcttctggta
    11161 attctcgttt aaagtctgca atgactgttg aaattgttgc ttcctcattg taacaaggaa
    11221 tcagaacagc aattttttct tgttgttcca tttttcactc tccttaacta tagaaaacaa
    11281 aagctaaatt aaaaatacct cataatcaaa ggaaatgcta gtttttcccg ctaaatatca
    11341 tttatttaaa aagaaaatac tggaatatat gtttggaaag ctctatctaa aaaaccaccc
    11401 actacaaaag aaggacatga tacctctctt ttgaatagtg ggtgcgtatt cgttctctca
    11461 cttttttgac gtattaatct gttgcacctt tttttcttga aatttctaat acggttcctg
    11521 tatgagcatc tgctaaaaat tcataataaa cagtttcgcc atcttctatt cgagaaagac
    11581 ctccccgata agcactcgac cgaacggcga atttcctaat aggttccttt tcaaaagaga
    11641 tccaagaacc ttcgattgca ccttctttta gaaaagatga cttgatattt tcaagtactt
    11701 ggtctgctga caatactttt ttgcgatgat accaaatcgt tgaagctacc ccgctcaata
    11761 atcctagacc gattccaact gctaacccgc ctttaaaata gcttagttcg ctttcttcat
    11821 acatgtggac atacctcctt cttctcactt gttactcctt gtgcttattt taccacactc
    11881 tcatattttc tttgaaataa ataaccgcta ccagaaaaaa taagctataa taaatacgat
    11941 cggtctgcag aaaaaatcat attttatccg cagatcaata taagtctgag aggagtttag
    12001 tctgaaattt agacgaatag catatggaag aaaaaacatt tcaacgaatc aaagagttaa
    12061 cagaattaca aggaacaagc ggttttgaac aagatgttcg cgcttatatg gaaagtcata
    12121 tggaaccgct ggtagatgag ttacagttag atggtttggg cggcattttt ggtctgcgcc
    12181 atcatgaaga agcggatgca ccccgtgtaa tggtcgcagc acatatggat gaagtcggat
    12241 tcatgctgac acaaatccaa gaaaacgggc tttttaaagt cgtacctcta ggcggctgga
    12301 atccttacgt tgtttctgct cagcgtttta cacttaaaac ctctactggt aagaattatc
    12361 catgtatttc ttcttccgtt cccccacatt tattgcgagg aacaagcgga caaaaatcag
    12421 tagaagtaac cgatattttg ttcgatgctg ggtttgaatc aagagaagag gcaatgagtt
    12481 acggtgtcct tccaggagac acaatcgttc cttacgctga aacgatcaaa acagccaacg
    12541 gaaagaatat tatcagtaaa tcatgggaca accgctatgg ctgtacaatg gtattagaag
    12601 ctttagaagc gttgcaaaat gaaacattag gtcatacatt gattgcaggc gcgaatgtcc
    12661 aggaagaagt aggcttgcgt ggttctaaag cttctgtcaa taaattcaag ccagatctgt
    12721 tctttgcagt agactgctct gcagcagatg atacagtgac gaaaaatggc acattcggac
    12781 atttaggaga aggtacattg atgcgtatcc aagatccagg tttgatcatg cttcctcgtt
    12841 tgcgcgagta cttgctggat atcgctgaaa caaacaatat cccttatcaa tactttgttt
    12901 caaaaggcgg tacagatgca ggtgctgctc atacacaaaa cgaaggaatc ccaagtacag
    12961 tgattggcgt agtgggacgt tatatccata cgcatcaaac gatgttcagt attcgcgatt
    13021 ttgaagctgc acgagaaatg ttgattcaaa cactgaaagg tttggataaa tcaacagtga
    13081 atacgatcgt atacggaaaa taatgcgata gtgaaactat aaaatctggc aaaagattgc
    13141 tttttgccag atttttttta taaaaagagg atcaatgttt gttagttcga aagaaaggtg
    13201 tataatttaa ttgaaaaata cataaacaga aagtagagga caaagaatga ttatcccaaa
    13261 tagtttagaa gaattagcag gctacgtaga aactggaaag agtgtatttt tctttactgc
    13321 cggctggtgc ggagactgcc gttttatcaa accgcaaatg cctgaaattg aaaatgactt
    13381 ttctgattgg caatttattg aagtagaccg tgacaagtac atagatgtag ccgctgaatg
    13441 gaacattttt ggtatcccaa gttttgtcgt gatccaagac ggaaaagaat taggtcgtct
    13501 agtgaataaa gatcgtaaaa caaaacagga aatcgaatcg ttcctagaaa gtgtaacaaa
    13561 aggctgacat ctgttaggag gggtcaagat gaatcaagaa tataagaata ttttagtagg
    13621 tatcgacggt agtgaacaag cacttgctgc tttcaaaaaa gcggtagaag tggctcgccg
    13681 taataatggg aaagtatatg tagcaaacgt aatcgatcag caattttata actttatggg
    13741 ctatgcacct attgatcaaa atctagtcga tcagcaaact gaaacagcca aggaaatgat
    13801 cgaagaatgt aaagaatatg ggaaatctgt tgattacaca aatatagaag gaattattgc
    13861 atatggttct gttcgtgaat ccatggcagt caaattgcca aaaaaatatg agatcgatct
    13921 aatcatggtt gggcagtcag gtctaaatgc agtcgaacgc tttatgacag gaagtgtagc
    13981 cagctacgtg atacgtcatt caccttgtga tgtcttgatc gtttctgacg aagaagaaca
    14041 gccaagtaat taagcaagtg gaacttgtac gaccttttta atcaattaac taaaacagta
    14101 aagggactgt gacaaaagtc ttgtcacagt cccttgttac gaataaatgg tgttccagaa
    14161 gaggcttctt cggaaataaa gcatgaaaaa aatttcatgc agtgaatgca attttttgtt
    14221 aagataaatc tcagcaaagg ataatggagg aaagaacatg atttttgctt ataacaaagc
    14281 acacgtcgga gacaccttga tggttattat agccgacgat aaaggaacag aaaacactgt
    14341 tgaacgcaaa tggaatgttg ctcggatcaa agatgaacaa ggtcaagttg ttgcttggaa
    14401 ctttttccat atctccgatc atctaacaat cgaagggaac ggccaagtaa gcttaacaga
    14461 tgaggaatta gcgaaattga atcgattgat caaagaagca ggattcgaag aacagcttga
    14521 agctgatcat gaaccgaaga tcgttgtcgg gtacgtaaaa acatgcgtcc cacatcctga
    14581 ttctgaccat ttatcgatta ctgagacaga agtagacaat ggtacagtat tgcaaatcgt
    14641 ttgcggtgca cccaatatcg aagctggaca aaaagttgtc gttgcaaaac caggagctat
    14701 gatgccagat ggaatgatga tctggccagg aactttgcga ggggtagata gctatggaat
    14761 gatctgttcc gctcgtgaat tgcatttgcc aaatgctcca gcaaaaaaag gaatcttagt
    14821 attgcctgag gatgccgtag tcggagaagc atttccaaaa taaagaggtt gtgacaagtc
    14881 tttgtcacaa cctctttttt attaattttc actattttga ttttgtttta atgccgattg
    14941 atcgatcgtc aattcaacag tagttgtttt ttctttcgag ccttcatagt aagtgatttt
    15001 gacagaatct cccacttttt tcttatacaa agcagattga agttctacac cagaagaaac
    15061 ttctttgtca tcgatcttag taatgacgtc gtattgtttc aatccagctt tttcagccgg
    15121 tgtagctgtt tggacatttg tcacgatgac accgttagtt acagatgaag gaatcttcaa
    15181 gatttgttct tgttgctgag tagaaacggc agataagtcg accattgtga tacctagagc
    15241 tggacgtgtc acttttccgt ctttttccag ttgattgatg atattcacta catcgttact
    15301 tggaatagca aatcccattc cttctacgct tacattagaa gtagattcag aagtacttgc
    15361 gatcttactt gagttgatac cgataacttg tccttcgata ttaactaaag gaccaccaga
    15421 atttccaggg ttgattgctg catctgtttg gatcgcattg atattgactg tttcgttcga
    15481 ttcattcgta cttgtcactt gtcggttcaa ggaagaaatg attcctgaag tgacagaatt
    15541 tgcatattca gatcctagtg gggaaccaat cgcaatcgca ggctcaccaa ccttcagagc
    15601 acttgagtca ccaaaagagg caactgtttc gactttgtct gaattgatct tcaacaccgc
    15661 taaatctgaa taagcatctg ttccaactaa ttcagctttt accttcgtac cgtctttcat
    15721 caagacttca agaccttgct ggccatctac tacgtgatta ttcgtgacta cataagcagt
    15781 attcccgtct tttttgtaga tcacgccgct tccttcacta taagcttcca aattactatc
    15841 atctgagctg ctactttctt cttgctgccc gaatagtccg ccaaaaccgc ttgattggtt
    15901 ttgactttgt aagttgataa cagaaacgac agcgtcttga actttatcta ccgctttggt
    15961 gatatcagaa tctacattga ctttgatatt ttccacaact gtttcaccgg cagaattctg
    16021 attgccgctt gtagcagtag aactattgtt gccagtgccc atcgctgcat aaaaaatgcc
    16081 agctgtcagt agtcctccaa cgatccctcc aacaagcccc agacctaact tacgccagag
    16141 gctattattt ttactttttt tcatctttgg tgtcacattt tttctatcca tgtgttcctc
    16201 ctccaattac attcatttat ctactgttag tatagtctta tttgttgact ttagtctact
    16261 ttgagactgt gaacttttta tgaaaaactt taggaaaaat cattgttttc agatgaaaat
    16321 atttgatttt ctttttccac agatactgtg taaaactacg cggataggat tggaaaaata
    16381 agggataaaa catatccaca gcctgtgtat aaagtggata aattcttata aaacgtatgt
    16441 ttgcctaatg aatgtgatga aataaggtaa aataacactg ttttctgtgg ataaacctgt
    16501 ggatgttgtg cataactgtt ggggaaatct ttttaacaaa aatagccaaa ataaacatat
    16561 agacgaaaaa attgattata ataaacaaag tgagcatgaa gaccaaagga gagaaaacat
    16621 gaatatcaaa attatctcag taggaaaatt aaaagaaaaa tacctgatcc aaggtatcaa
    16681 tgagtatgtc aaacggctga atgcctatgc aaaaatcgaa ttgatcgaag ttcctgacga
    16741 aaaagccccg gagaatttaa gcgaagcgca aatgagacaa gtaaaagaaa aagaagggga
    16801 acggatctta gcgaaaatca aagaacaaga atacgtctat gccttagcaa ttgaagggaa
    16861 aaatcctaca agtgaatctt ttgctaaaca aatcgaccaa ttaggtatcc aaggaaaaag
    16921 ccaccttgtt tttgttatcg gcggctcttt aggactcagc gaagccgtca tgaaaagaag
    16981 caatgctcag atctcttttg gaaaaatgac gtatccacat caattgatgc gtctgatcct
    17041 tgtcgagcaa atctaccgtg ccttccggat caatgcgggg gcgccttatc ataagtgatg
    17101 cggtttttat cattgatcct aaaaatctta gcaagacaaa aagtacgtaa gaaagtaaag
    17161 actaaatact tcggaggaac aaatgaataa caatgatagg ttattgcgat tgcgttatgc
    17221 gattgatttg aaagatacgg atttgattaa agcttttgag ctaggcggtg taccactgac
    17281 taaagaagaa gctcaggcgg tactgaccaa agtacaggat aagaacaaag ataatgcaga
    17341 aaataatgtg tatgaaaaaa ccatcaacaa ccaagttttt gacgcattcc taaatggcct
    17401 gattctcttg gcgcgtggtc cgcaaaaaga taagccgata gtagacacgc cgcaaaaaag
    17461 caaggaaatc aaatatatca acaatgtgtt gctaaaaaaa ttaaaaatcg ccttgtctat
    17521 gaccactgat gatattttag acgtttttgc tgaggcagaa atctatccat caaaaggcga
    17581 aatcggggca tttttgagaa aagaaggcca acgaaatttt aagccttgcg gagataaata
    17641 tatgcgtaat tttctcaagg ggttaggaat ttataatcgg agaaaagtat aaagaaattt
    17701 catgagaaat caaaacaatg gttgttttga tgagagctag tttttgtatg agattaaaat
    17761 attatcttaa tcgaggagct ggattggttt tatgaatgat gaatataaga atgatgaaga
    17821 taagatgctt tttgaagaga tagagaatcg atgtaggctc aattttgagc ttcggggaaa
    17881 gatgtcttta atacaacaaa aaaagtattt agcgaataaa tcagagttta ctctgggaca
    17941 tgttgaaaaa ttaatctcgg attggattag tagtagaagc gaatttacaa aaataaaaca
    18001 gccgattaaa tttgacatga aaaaactttt gttaaataag agtgagatag gtaatagaga
    18061 tcaatatatt agagctaaag ggcaagaaat aattgattca ttaggtgaaa tgaggtcata
    18121 caattatttg tatgtaacac atagagctga tggaatggtc attactgtgg ggaaatcttc
    18181 ttctaatgat atttttttag atggagatct tttttatcaa ctcaatacaa atcacttgtc
    18241 tggcactgaa aatataattt taaggacgga atatggcaat gaaatatttg caaaatatga
    18301 tgagatttta aaaaattatt tggactgggc ttggataatt ccggttgagt caggagatgc
    18361 taagaaactg gagagattat tgggcgatga actaattaat aaaaaagtac caattttaaa
    18421 ttattattcc catagacaat aaaaggctat ttttcatgat aatactagtt ataactgtaa
    18481 aaatggaaga aaatctggga aagaagtttt taaataagtg tattgttcga ttttaataaa
    18541 taataagcaa taccatccgt ctgtgttgcg caacatcgta ctacaatgaa tattttttca
    18601 caaaaagaaa atcatccatc gaatgaatgg aaggttttag tatacacgag gttaatgccc
    18661 cctcttttat aatcagagga gtgaggtttt ttctatgaat gtttctattt tcttattgct
    18721 agtctagttt ctcttacgat gaaattggga ttctattcca gtttttattg atttgctgat
    18781 aaaataactt gaatggtgga tataaacatg ataaataaga gaagaataac aaaacaaggt
    18841 tgtgaaatga ttctcaaatg aatataatag aaagaaaaag gaggaagaat caatgaaaat
    18901 agcaattgca ggcgctggcg caatgggaag tcgctttggg ttaatgcttc accaaagtgg
    18961 gaacgaagta ttattaatcg atggctgggc agaacatgtc caacaaatca aagagcatgg
    19021 attacaagca aattttaatg gtaaagaggt agaagcaaaa ctaccaatcg ttcttcaatc
    19081 cgaagtagaa aaagaagatc aagttgatct gattattcta tttaccaaag cgatgcagct
    19141 ggaaaaaatg ctgcaggata tccaatcatt aatcaaaaaa gatacagagg tcttatgtct
    19201 attaaatggt atcgggcatg aagatattat tgagaaattt gtaccaatgg aaaatatcta
    19261 tattggaaat accatgtgga cggcaggtct tgaaggtcct ggtcaggtca aattatttgg
    19321 aagtggttca gtagaattac aaaatttagg tgatggaaaa gaagcagctg caaaaaaatt
    19381 agcagacaaa ttgtctgaat caggattaaa tgctcatttt tctgacaata ttcactattc
    19441 tatttatcgc aaagcatgtg tgaacggaac aatgaacgga ctatgcacaa tcttagacgt
    19501 taatatggct gagctaggaa aaacatcgac tgctcataaa atggtggcga cgattgtcaa
    19561 tgagtttgcc aaagtagcag cagtagagaa gattgaacta gatgtcccag aagtcattgc
    19621 acattgtgaa tcttgttttg acccggaaac aattgggtta cattatcctt caatgtatca
    19681 agacttgatt aagaaccatc gattaacaga aatcgattat atcaatggcg caatttctag
    19741 aaaagggaag aaatatggtg ttgcgacgcc ttattgtgat ttcttgactg agcttgtcca
    19801 tgcaaaagaa gatagtttga acgtaaaata aaggagagat tgaatggaaa cttcacaaaa
    19861 aatatcaccg aaaatttttc tgaataaagt cctcgctggt acagcaacag gaatcattat
    19921 tggattgatt cctaatgcag tattaggtgc cattttaaaa tattttagtg cgtatccctt
    19981 tgcggtaacg atcgcacagt tagcagttat ttttcaacta gcaacacctt tgatcattgg
    20041 tggtttgatt gccttacaat ttggatttga tccgatgaga atgatggttg tagccggagc
    20101 ttcttttgtt ggttctggtg tagtcaaatt cacacctgat ttgggtgaaa cgggtgttta
    20161 cgttggtgct ggtacaggcg atattattaa tacgatgctg acagcatcga ttgctgtcgg
    20221 gctgatttta ctgattggaa atagttttgg gtcagtgtcg attgtgttaa caccgattgt
    20281 tgtaggtgta ggtgcaggtt tacttggttt ttatttattc ccttttgtaa cagcaattac
    20341 ttctgcaatt ggatcattga ttaataactt cactacctta caaccgctgt taatgtctat
    20401 cttgattggt tgttcctttg cctttttgat tatctctcct atttcaacag tagcaatcgg
    20461 aatggcaatc caactagatg gtgtttctgc tggtgcggct gcgatgggcg tagctgcaac
    20521 cacttttgtt ttagtagtga actcttggaa ggttaataag tcaggtgtga caattgcgat
    20581 tgctttaggc gctatgaaga tgatgatgcc taatctattt agaaaacctg tgattcttat
    20641 tccttgttta gttagtgcag tgattacagc tattcctgtc gctctatttt ctatttcagg
    20701 tacgcctgct tctgctggtt tcggcgtggt cggacttgtt ggtccgttgg cttctttaga
    20761 tgcagggcta aatggctttc ttgttgttct ttgttggtta gtcatccctg tttttgcggc
    20821 actaattact caatttttat gcgagaaagt atttaaactg tatgatcgag aagaagtctt
    20881 caaattttta ggctagtaga ttttactaag aaattttcaa tcaatggatg cgtaagtgag
    20941 atgtcaacaa catctgactt acgttttttt gcctttttga gtaggagatt gatgctgaca
    21001 actgaactct tcagtgccat tcgatttttt aaaatgtaga agaaactcac ctttatgtta
    21061 ttgattgttc aaaaggcaac tagaataaaa atatgtgtta aaatgagaaa aaatttgatt
    21121 gttggatgta tcgaataatc actaaaaagt aggagaagaa aatgattttt ttgcaaaaat
    21181 atggttttta ttttttatta ttaggtgtga ttagtgattt atcgacaccg tatatccttg
    21241 gcctttttta tcccaaactg aatcaaatga ctaccgtaat tagtgtgttt ggtgacgtag
    21301 atagtccagt cagacgtgct ttcttggtct ggtcagttgt atctggactt ttttttgttc
    21361 tttcgttgcc tgcgttgtat cacctattta ttggaacatc aaaaacactt gcaatacttg
    21421 ctgttgcaac agttggttta tatgggatag gtgattgtat ttttactggg ttattcagta
    21481 tcaatacgaa tgaaagctct tggaatctat cgacttggat ccataatata ggttctgggc
    21541 taggctatgc aggctttcta cttttcccat tgttacttgt tctgctttat cgtcaaagtg
    21601 gtcaaggtac gcttagccat ttttatcttg ttttaacagt tattagttta ctaattgcag
    21661 gtctttacag attagcacgg attccgtcga ttagtcagtt tgccttcttt aagcaattgg
    21721 gcttctttca acgcttaagt tttttcttta actatttgcc gatgatttgt ttaagttttt
    21781 ttcaactacg aaagtagaaa aagcagtgtg aagctgatta agtaaaagaa tttctctatg
    21841 ggtaaccatt cgtgtggatg tgttcgacta agaatagaga tgaggagagc gaaaagcaag
    21901 ttagtcttaa cttgttatgc gttgtgctaa atttcaggta gtcatttttt gaatgaataa
    21961 gaagaaaact tgaaagaggg tgacttcatg ttagatgtgg agcagatgga aatagacctt
    22021 tataatatta ttttaaatcg aaatacaaga gaatgggaaa gaacacaatt tgaagaggca
    22081 aaagaagacc tagcaaaaat gtcgataaag caggtgatag aaaaactaga ggtcaacttg
    22141 cgtccgctag cactacgaga taatttgaca ccagatgcga tggattttta tttaagaatc
    22201 acaggggagt cagcgagtgc aaaggcttat gattatgcca aacataagat aacttcaccc
    22261 ttataccaag aacgggcgat ttttgccggt ggctgtttct ggtgtatggt tgagcctttt
    22321 gaaacaaaac caggtgtaat ctcagtgtta tctggttata caggtggaga gaccaaaaaa
    22381 ccaaattacg atcaagtcag tggtggatat actgggcatg ttgaagctgt tgagatcata
    22441 tttgatacac gtcaaataac ctatgaagag ctgttggaga tttattggca aatttcagac
    22501 cctacagatg cctttggtca atttcaagat cgggggaaac aatatcgttc aattctattt
    22561 gttgttaatg aaaagcaaag gcaattggct gaaaaatcaa gagaacaact gattcaatct
    22621 aaccgattta gccgtcctat cgttacagag attcgccaag caaagacttt ttggccagct
    22681 gaaaatcatc atcaacaatt ttatcagaag caacctaaaa gatataaaaa gatcaagcat
    22741 tcgcatcagc ttcatttatt ttttcagcga catagataga ggaaggttgt ggcgcaaagc
    22801 gttcagctcc gacaaaataa tgagcaactg acaaaaatag cttttcatat ttttggacag
    22861 ttatgaatta tttcgaggag ttgctttgag aacaccgagg aaaaggttgt ggcgcaaagc
    22921 attcagcttc aagtcgcaag gaaacaggag gtatgacaag tcttttgtca caactcctgt
    22981 ttttttacta gcctttattt ccatgtgaaa gagaattcga attgtagaat cttgattttt
    23041 ctatggaatt ttgtagagaa tcatcttgat aattaataga cacctaatcg aattccacat
    23101 taatgatgaa ctaaattccg tataaaagcg caaacaataa ctata
//
LOCUS       DASHWW010000038        23012 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.038, whole genome shotgun sequence.
ACCESSION   DASHWW010000038 DASHWW010000000
VERSION     DASHWW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.038"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(260..1492)
                     /locus_tag="U2R64_001690"
     CDS             complement(260..1492)
                     /locus_tag="U2R64_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEM8918512.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1747..2316
                     /locus_tag="U2R64_001691"
     CDS             1747..2316
                     /locus_tag="U2R64_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8918513.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2494..2934)
                     /locus_tag="U2R64_001692"
     CDS             complement(2494..2934)
                     /locus_tag="U2R64_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEM8918514.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3092..3856
                     /gene="map"
                     /locus_tag="U2R64_001693"
     CDS             3092..3856
                     /gene="map"
                     /locus_tag="U2R64_001693"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HEM8918515.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3888..4811
                     /locus_tag="U2R64_001694"
     CDS             3888..4811
                     /locus_tag="U2R64_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEM8918516.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4887..6026
                     /locus_tag="U2R64_001695"
     CDS             4887..6026
                     /locus_tag="U2R64_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEM8918517.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6019..6819
                     /locus_tag="U2R64_001696"
     CDS             6019..6819
                     /locus_tag="U2R64_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8918518.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6819..7646
                     /locus_tag="U2R64_001697"
     CDS             6819..7646
                     /locus_tag="U2R64_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8918519.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7624..8358
                     /locus_tag="U2R64_001698"
     CDS             7624..8358
                     /locus_tag="U2R64_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8918520.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8458..9324
                     /gene="rfbA"
                     /locus_tag="U2R64_001699"
     CDS             8458..9324
                     /gene="rfbA"
                     /locus_tag="U2R64_001699"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEM8918521.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9338..9910
                     /gene="rfbC"
                     /locus_tag="U2R64_001700"
     CDS             9338..9910
                     /gene="rfbC"
                     /locus_tag="U2R64_001700"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEM8918522.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9932..10960
                     /gene="rfbB"
                     /locus_tag="U2R64_001701"
     CDS             9932..10960
                     /gene="rfbB"
                     /locus_tag="U2R64_001701"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEM8918523.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11058..11909
                     /gene="rfbD"
                     /locus_tag="U2R64_001702"
     CDS             11058..11909
                     /gene="rfbD"
                     /locus_tag="U2R64_001702"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEM8918524.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11943..13976
                     /locus_tag="U2R64_001703"
     CDS             11943..13976
                     /locus_tag="U2R64_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918525.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14020..15299
                     /locus_tag="U2R64_001704"
                     /pseudo
     CDS             14020..15299
                     /locus_tag="U2R64_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15509..16315
                     /locus_tag="U2R64_001705"
     CDS             15509..16315
                     /locus_tag="U2R64_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918526.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16327..17547
                     /locus_tag="U2R64_001706"
     CDS             16327..17547
                     /locus_tag="U2R64_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918527.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17537..19123
                     /locus_tag="U2R64_001707"
     CDS             17537..19123
                     /locus_tag="U2R64_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8918528.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19162..21300
                     /locus_tag="U2R64_001708"
     CDS             19162..21300
                     /locus_tag="U2R64_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8918529.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21668..22651)
                     /locus_tag="U2R64_001709"
     CDS             complement(21668..22651)
                     /locus_tag="U2R64_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEM8918530.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7217 a         3934 c         4747 g         7114 t
ORIGIN      
        1 cgagtctctt ctttctgagg agagacatca agagtcgctg cgctactgct cctgacctct
       61 ctcctcagaa agaaaggcat ggcagttagg ttcacaacgc aaaacattgt gcttttgatg
      121 aggttgaact tttacacaag attgtggact tgactaaaaa aacggtgggg ttgtttagcg
      181 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata ttattttttg
      241 catgtgtgcg aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc
      301 catcttcacg gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg
      361 tttgacttct attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt
      421 tcacactgaa ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata
      481 atgtattgaa aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga
      541 cttctcctaa acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc
      601 cttgttcggc agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga
      661 tgatggtgcc agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac
      721 tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag
      781 cattatagct tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg
      841 taccgggagc agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt
      901 ttgctaattt ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag
      961 tcgttttgaa aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga
     1021 agacttttgc tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg
     1081 cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta
     1141 ctcgatggct atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc
     1201 ttgctccttt ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa
     1261 tacgatccgt tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa
     1321 cgataacctc agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg
     1381 cctgttccac gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt
     1441 ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa
     1501 ttcctcctca ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa
     1561 caatgaggct ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat
     1621 gttactactt gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa
     1681 aaacatgtta caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta
     1741 aaaaatatgg caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa
     1801 gtagctgcca ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat
     1861 tgttccacgc aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt
     1921 tttgagcaga tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat
     1981 acgattatcg atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat
     2041 cgttcactgt acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact
     2101 tactttgtga atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc
     2161 gaatctttgt ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca
     2221 agcatcatcc atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct
     2281 atcttgaaat tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc
     2341 agtaggtaac aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca
     2401 tttttaactc ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga
     2461 ataaatctgg atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc
     2521 gaaagcttct aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc
     2581 ggctcctttt gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca
     2641 gaattcatcg taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc
     2701 caattcttgc aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta
     2761 tgtataagta gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt
     2821 acattcgttg atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc
     2881 gatttcttca gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg
     2941 cctcctcgtt tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa
     3001 ataaaaccta gagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa
     3061 tgagagggat ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat
     3121 tgaaatgatg gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt
     3181 tataaaacca ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag
     3241 tcatggcgga attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag
     3301 tataaatgat gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt
     3361 ggtaaaagtc gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta
     3421 tgtagttgga gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt
     3481 gtacatcggt attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat
     3541 ccaaacttat gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt
     3601 tggtcctacg attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt
     3661 gcggttgaaa gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa
     3721 aatgaaaatg gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca
     3781 atatgaacat acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga
     3841 agaaggcact tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga
     3901 acaaaataaa acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca
     3961 ctgattcaga aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat
     4021 ttccattgat tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg
     4081 tactgaccta tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa
     4141 tcaaagacct tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt
     4201 tatggtctgc aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg
     4261 tagaaaatag aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt
     4321 tcatgattgc tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg
     4381 ctattcagcc aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt
     4441 ggccaatcac attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta
     4501 atgctcagtt gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga
     4561 tgctgttatc acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt
     4621 atcagatcat aggaagtttt attgtactca tgctttggct taattttgct gctacgatca
     4681 tcattttggg cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca
     4741 aaaaacgtcg agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata
     4801 aaaaaaagta gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat
     4861 gactcttaat taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt
     4921 ttctgacaat tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa
     4981 caggtatggt cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg
     5041 gcggactgcc tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta
     5101 tccctcaatc gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag
     5161 tgctcgatga taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt
     5221 ctcttattat ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg
     5281 gatatatcca actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca
     5341 cgaatgcggt caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg
     5401 gtttaattac gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc
     5461 cagttgttat tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc
     5521 cggcaaagat ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc
     5581 tttcactaca agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca
     5641 tgggagtgcc ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt
     5701 ctttttctac agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc
     5761 ataaaggtgc tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg
     5821 tcatgaatta tactggaaga atcggaacga tcatattgat tattgccatg ttgtttgctg
     5881 caattttatt atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa
     5941 cattgcgatt tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga
     6001 aatggaaccg tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg
     6061 acggcaaaca gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat
     6121 gaaacagcag taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga
     6181 ctaacagagt ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga
     6241 tttggttatg gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt
     6301 aacccagata ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa
     6361 catccggaat gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac
     6421 ctcatccgtg agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg
     6481 gtcaaaaaaa agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat
     6541 gctaatagtt atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt
     6601 aaagagataa aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt
     6661 ttgagttttg aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat
     6721 ttttacggga agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg
     6781 atgaaatttt tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag
     6841 tcgttgtgct ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag
     6901 cacttagcga aaagcaaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa
     6961 atgagctgtt tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag
     7021 cggtggctta taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc
     7081 tggatcagga tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta
     7141 cagatgaatg tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc
     7201 tatattcaga tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag
     7261 ctgaacgaat catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga
     7321 ttggcgggtt taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag
     7381 tggatcagtt ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg
     7441 ttttagacta tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc
     7501 gattttatca tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa
     7561 gaacagctaa acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct
     7621 catatgttaa gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat
     7681 ggaggcagat atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat
     7741 gaagtagtca tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac
     7801 gcagaaaaag ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat
     7861 tttggttatg cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat
     7921 gtttggttgg agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag
     7981 ctagtagtag tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg
     8041 tatttttcgt ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat
     8101 attggtgctg gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca
     8161 gaagtgccga tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta
     8221 agagaaccgt taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat
     8281 tctaaattac ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga
     8341 aaatggttta aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa
     8401 caattgatga gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg
     8461 aagggaatca ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca
     8521 tcgaaacaat tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg
     8581 atgttggcgg gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc
     8641 aaggaattat ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa
     8701 agtccagatg gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt
     8761 gtctgcttgg tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa
     8821 cgagcagctt caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa
     8881 cgctttggtg tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct
     8941 gctcagccaa aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt
     9001 tctatcgcta aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat
     9061 aaagcatatt tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg
     9121 cttgatacag gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa
     9181 aaacgtcaga acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc
     9241 gataaggaac aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat
     9301 ttattgaatt tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt
     9361 aacagatgtc aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga
     9421 aagttattca aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa
     9481 ccattcacta tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc
     9541 tgcacagaca aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat
     9601 ccgcaaaggt agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca
     9661 tcgacagttg cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt
     9721 gaacttcctt tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt
     9781 tgatgatcca gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga
     9841 aaaagatcac cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg
     9901 agaaatctaa gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc
     9961 cggattcatc ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt
    10021 cactgttttg gataaactga cttatgcagg aaacaaagag aacttggctg gacttcctag
    10081 cgatcgcgta gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt
    10141 aaaagaagcg gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa
    10201 agatcctttc ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg
    10261 ccgcaagtat gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc
    10321 attacgtgaa gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac
    10381 accatataat ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa
    10441 agcatgggtg cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg
    10501 tccttatcag catattgaaa aatttattcc tcgccaagta acgaatatct taagcggtat
    10561 tcgtccaaaa ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca
    10621 ttcttcagca gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg
    10681 tgcagacggt gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggtca
    10741 accaaaagat gcgtacgacc atgtaaacga ccgtgcagga cacgacttgc gttatgcaat
    10801 cgattcgaca aaattacggg aagagttagg atggaagcct gagtttacga acttccgtga
    10861 tgggttggct gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa
    10921 agaggccgtt gaagcagcat atgccaaaaa tggacaataa tacagagaaa atgtcactgt
    10981 attaatggaa aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc
    11041 aaggagcgga taatcatatg tttttattaa ctggaggaaa tgggcaacta ggtacagaat
    11101 tgcgccattt attagatgaa aaaaatctgc aatatgtttc aacagatgca aaagacttgg
    11161 atatcacaga tgccgagaaa acaatggctt acatcacaga attaaaacct gatgttattt
    11221 tccattgtgc agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg
    11281 agaagatcaa tgttgatggt acaagaaatg tagcacttgc agcaaaagct gtgaatgctc
    11341 aattcgtcta tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg
    11401 aagtagacga ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa
    11461 aagcagtaga agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga
    11521 tctatggaca caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga
    11581 ctgtagtaaa tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg
    11641 tatatgtcat cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct
    11701 gttcttggta tgaattcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg
    11761 ttacgtcaga agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga
    11821 aaaagacaga agagttagga tttgtcatac caacttggca agaagcactt gcgcaaatgc
    11881 tggaagctgc caaaaaaatg aataagtaat ttccttttat caaatagaat ttggagcatg
    11941 atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aaccaggcag
    12001 attcgaattt ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca
    12061 tcgtggtcat cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg
    12121 tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc
    12181 ggtcagacga atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttc
    12241 cgttggtgaa cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc
    12301 ctgtaaagga tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa
    12361 gagatcgagg actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat
    12421 tcgaagtact gatgatatta acgaagagaa aaaaagctct atcgctaatc ggtgcatttg
    12481 cgctgacatt ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt
    12541 tctttacttt gggactgatg actgcttttt atcattattt ctacaatcat gataaaaaat
    12601 ggctacgaac gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga
    12661 tttacccagc ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc
    12721 ttatttacta tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg
    12781 cagttttatt tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt
    12841 tagcttcttt gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga
    12901 ttggcgaatt tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt
    12961 cgaataactc tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc
    13021 catttgtgtt atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga
    13081 ttttttgtct gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa
    13141 tcactctgct gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt
    13201 gtttattatc gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt
    13261 ataaattcat tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga
    13321 aaatggataa ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga
    13381 ttttagcttt tgcattattt ggctggagac gcttgtttta cctcgctttt gccgccttag
    13441 ttatcgtatc tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa
    13501 aaacactggc aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt
    13561 ctgaagatga attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac
    13621 gcttttatcc agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt
    13681 attataatcg gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt
    13741 tagatcgtcc agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga
    13801 tcgactatgt gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt
    13861 tcacgcagct atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg
    13921 attatccaga tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg
    13981 ctagctgaga ataatcctga aatgttagta gaaaggagag tggagataat tcaagcaatc
    14041 gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttact gacgctagtc
    14101 ttttttgttt ggacagcagg gttaggtttt ccagcaactt tgtttatata taacaatagt
    14161 tcattactta tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa
    14221 ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt
    14281 cgggaattaa gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt
    14341 tgtttagtaa ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc
    14401 ttttcggtct tcctcggaat cacgtttatc gtgtatttac agagatccaa gtaccagaag
    14461 gacaaagcat ctgggctcca ggcaattcgc tttctgatat ttggatcaat acgaatacaa
    14521 tcggaagttc tttgatgact cttgctttat tgatcagtgg atttgccagt tcttttgaac
    14581 gatggtatgt acgaatcatc ggtgcagtag cagttgttgc agcttttctc gggatttggg
    14641 tctgccaatc tagaggtgca ttagtcgcgt tgattgtttt tgcgatattg gatcttttac
    14701 ctaaatcgtt gatgcgtgtc attcgtgcgc catttattgc ttacacggtt acgattcttt
    14761 tagctttgcc gatttcttat ctggcggctg tctctgaaaa agtcaatttg tttaccggtc
    14821 gagaagatat ttggcataaa ttctatcaga cgctaggaga aaaatctgaa caaattttac
    14881 taggaatgaa aacatttatc ttccaacgag gaaaccaatt tttaggaaac cacaatagtt
    14941 ataattctat tttgaatatc tatggattga taggatttgg gattgctgct ttgctgctta
    15001 tcctttttat tggtcgctta acgttgaaag cagatttatc caacgggcag atgactttta
    15061 tctgggcctt ttttgcggtg atgatgcagt catttatgga ggatacattg acttcataac
    15121 catgggttcc gattatttat atcctgttgg ctatggccgt tcatcgatat gatgaaccag
    15181 aagttgcgga ggaattctat gttatggaag aggcatatga cgatatgact tatgatgata
    15241 catcttatga ggaacaacca gatagcgctc attcttccag gatccaacgc tatcattgat
    15301 aggcacaaaa tacgagagag gctgtgacaa ccgtcgcagc cttttttggt ttattgcaat
    15361 tgtctagcat cttctgtaaa atagaaacgt tagagaaaat cttgtatcat agaaaattaa
    15421 gaaagaaata agaacgcagc tcggtaccaa aaatatggta aaatggcact tgactgtaat
    15481 tcactgaaaa tcgcttggag gaacacaaat gtttaaagat ttgtatttat ttatgaagga
    15541 catttatcag aacagaaaat tattgctaca gttttcgatc aatgacttca aatcaagata
    15601 tgcaggatcg tttttaggaa tcttatgggc gtttatcaat ccgctattta ctgtattgat
    15661 ttattggctg gtatttggtg ttggactgaa agcacaaatg atcgatgcaa aatacccatt
    15721 tatcgtatat ttagttaccg ggatgattcc ctggttcttc ttctcagatg catttgcatc
    15781 aactacggtt gtttttcggg aatatactta tttagtaaag aaagtcgtat tcaatattcg
    15841 tatcttgccc acgacgaaaa tcctatccaa tctgtacacc catttattct tcattctgat
    15901 tggcatagct gtcgcgctta taaatggtat atatccttca gcaatgtctt tacagctgat
    15961 ttattattta ttttgcatgt gtgctttctt gacaggattg acttggctga cggcatcgat
    16021 ccaaccattt ttacctgata tcatgcaatt aattacgatc gtgctgcagt tgatcatgtg
    16081 gacattaccg atattatgga gccctaatca gtttgattca ggtcttgtaa gcatattgaa
    16141 attaaatccg ctgtactatg ttgttcaagg ttatcgtgag tcatttttaa gtgaagcttg
    16201 gttctgggag catggaacat atactttgta tttctgggtt ttcacgttag taatgttcgt
    16261 aatcggctct gcagtgttcc gtagattgaa accacatttt tcagatgtgc tgtaaggaga
    16321 atagctatga cagaatatgc aattagacta aaagatatca caaaatctta taatatgtac
    16381 gcaaaacctt cggatcgatt tcgtgaagcc ctcaatcctt ttaagaaatc ctatcatgat
    16441 gtattttatg cgttgaaaaa cgtgaatgta gaaataaaaa aaggtgagat gatcggtttc
    16501 gtgggagaaa acggatcggg aaaatctaca atgttgaaaa tcattacggg agtactgaca
    16561 ccaacatccg gcacgatgga aatcgaagga aaaatctcag ctttgctaga actaggatca
    16621 ggattcaatc ctgagtattc tggctatgaa aatatctatt taaatggaat ggttctagga
    16681 ttttcaagag aagaagtcga tgaaatggtc gatgatatca ttgaatttgc tgacatcgga
    16741 gaccatattt atcaacctgt aaaaacttat tcaagcggga tgttcgttcg tctagctttt
    16801 gctgtagcaa tcaatgtgaa tcccgatatt ttgattgtgg atgaagcatt ggcagtaggc
    16861 gatcttgaat ttcaactaaa atgtatggaa aaatttacag aaatcaagaa ctcgggaaag
    16921 acgattttat tcgtttctca tgatatcagt tcgattcgtc gtttttgtga tcgttcctat
    16981 tggttgaaaa acggagaagt cgtcgaatat ggcgatacga tggaagtaac gacgaattat
    17041 gaaaactttt taaagaaaaa atcagttaaa acagtggatc ggaataaaaa ccaagtagaa
    17101 cggttcgccg ctccagatat cgtcgacgtg acgaaagcgg aattgttgga taaagacaaa
    17161 aatccggtgg atatgctgga acaaggagaa aaactatacg ttaaagtaac ttatgaagta
    17221 aaagatgata caatcaaaaa tccggtttta ggaattgcgc tacgaacagt cgacaatttt
    17281 tatgtatgcg gacttaatac tctactagat ggtatcaaga ttccttggaa aaaaggagag
    17341 aatatctttt atctggagta tgaaaagtta ggtttgttag ctggtgaata ttattttgac
    17401 gttgcggtct ttgaagaaaa tgcaacggtt cctttggtat ataagacaaa gtacatgaac
    17461 ttgtttgtca gcggttctta tatcggagaa ggcatcgtgg tcttagacca taaatgggaa
    17521 gaagggactc atagcaatga aatatgattt tgaaatggac ctagatgaac aaagcagtgt
    17581 gggaaaaatt gccgcacaga tcaaaccagg aagtaaagtt ttagagtttg gtcccggaaa
    17641 cggccgatta acgaaacatt taatcggagc aaaacaatgt gaagtgagca ttgttgagtt
    17701 agataaggaa ttgttcgatt ttgtcagcga atttgctcaa gatggatttt atggtgatat
    17761 cgaaagtttt gagtgggcaa actattatgc tggacagaca tttgattacg tcttgtttgc
    17821 ggatgtttta gaacatttgg tagatcctgg aaaaacattg aagaaagtca gagaattttt
    17881 gaatgaagaa ggagagatcc tgattacatt ccctaacttg gcgcataatt ctgtcatgat
    17941 cgatttgttc aataaccaat tgccgtgggc ttcttatggt ctcctagatg aaacccataa
    18001 ttctttttat actcatgatg gcttccaaaa agtttttgaa aaagcgggat tattcattaa
    18061 tattgaagat tatttgtact tagctgtagg tgatacagaa ttaaaatcaa cttatgaaga
    18121 attgccggaa gctgtacgct atgatttcaa aatgcgacca tttggtgaag tctaccaata
    18181 ctttttctca ttgatgaaac atccagtagc acaaagttcc attgcagagc cacaaaattc
    18241 taattatgta aaagtgttag aagtaaccca gcaaacgaaa caagatgaaa caatccaaca
    18301 aataccattc aataatttca caggggaaaa tgagacacta agtttccccg tatcagaaac
    18361 aacagaaaga atggtgtttc gcttcgcgca acaacctagc tttatcgaat tcagcgcaga
    18421 agctgccgga gaaaaactaa catttatcga ttcgaatgct gtagtcaaaa cagtaaatga
    18481 ttgttatttg tttgatggga aagaattacc agagttcgtt ctaacggata tttctgggaa
    18541 agaagtgact atccattgtc actatcgctt tatcggggaa ttgacaccaa caatgaaaga
    18601 attgttggaa acgattcgtc ccatggctga agtcacaaag cagctttctg agaaaaatga
    18661 cgaattagaa agagaaaatc atcatcttct tgaggaaaat acaagactag accatacgtt
    18721 aaaaacaacc acaaatcgct attgcacatt gttggaaagt gatgaatgga caataaaaca
    18781 tagactagga cgacgtaaga aagaaacttc gaaaaaaatc caagaaaaag aactttctat
    18841 atgtattgac gagaaaatct gggatgcaga aacaaaaata ttaaaaatca tcggatgggg
    18901 aatcgctaat tcggatcgcc agcccttgtc ctataagtta tcagctgacc aatcgccatt
    18961 tttcgaagca attcctgttt cacgagaaga agtcaatcaa gcagaacagc tcgcaaaagg
    19021 aacagaagcg ggatttgagt tacgaatcct ttgcgagcaa gaacgttcat tcttagtgga
    19081 agcagtagct caaaatggcc aatcatggat cattgaaatg taaataatga ttaacttata
    19141 aagataagga gtaaacgaat cgtgcaaaaa aaagaaattg ccgtatttat cgatcaaatc
    19201 actcgtgaac gggccactgg cgatttgctt attgtgggct gggcaattga tgaagtgacc
    19261 aaagaaatcc ctacgataaa ggtagaaaaa gaaaatgtga ttgctgaagc aacacatgtc
    19321 gtaagattgg atatcaatca tttatataat cttgatgtta agacccaaag cggttttaag
    19381 gtacgtttat cagggaaaat gagaggaaaa gccatcttag acttccaaac agcgagacat
    19441 caaaatggca tagctgtgaa attaaacggt aaataccctt atgatgacgg cattgaatct
    19501 tcatgggaaa gaaaaaaaag attactgaaa aaagggataa attatgcaag gactcatggc
    19561 gtaaaaaaag cgatccgtcg ggtcaaattg gaattgaagc caggatcgat cgactatgca
    19621 gagtggatca gtcgtcatga gaaaccagat ttgaaagagc aaaggaaaga agcacaagga
    19681 tttgcgtacc gtccattgat ttccatactt atgcctgtct ataacgttga aatcaaatgg
    19741 ctcgaaaaat gcattgattc ggtactggat caaacgtatg atcattggga actatgtatc
    19801 agtgatgatg cttctactga tccagctatc cgaaagtgtc tggaatccta tcaagcaaaa
    19861 gatgatagaa tcaaagtcgt tttccgaaaa gaaaatggac acatcagtct ggcaactaat
    19921 tctgcattgg aaatagcaga aggagaattt atagcactct tagataatga tgatgaatta
    19981 ccgccatttg cattatatga agtggcaaaa gtgctaaacg tacatccaga actggatgtg
    20041 atctacagtg acgaagataa aatcgatgca gatggcaatc gctttgatcc gcatttcaaa
    20101 gcagactggt cgcctgatac attgatggga aataattata tctctcactt aggcgtatat
    20161 cgaacaagca ttgttaaaga acttggcggt ttccgtaaag gctatgaagg ttctcaagat
    20221 tatgatttgg tccttcgtgt gacagaacaa atccctgcag atcatattta ccacattgac
    20281 cgagtcttgt atcattggcg gacgatccca ggatcaactg caagtaatgg cgaagccaaa
    20341 agttatatct atgattccgg agtgaaagca ttgacagatg ccctgtctag aagaaacatc
    20401 aaaggaagcg tacgtcctgg cagaatttct ggattttatg agattgctta tgacgtcttg
    20461 caagaggatt tggtcagtgt gatcattcca acgaagaatg gctatgaaga tctaaaaact
    20521 tgtgtggatt cgatcatcga aaaaacgtct tattcaaatt atgaaatcat tattgcggat
    20581 aacggaagta cagatccaaa aatgcaagaa ttatttgcag aatacaagca tcagctgaaa
    20641 gaccgcttta tcgtagaatt gattgacatt ccattcaatt attctcgaat taacaattta
    20701 gcagcagaaa aagcaaacgg caaatacttt ttattcttga ataacgatac agaagtgatt
    20761 gagccagatt ggatgacggt gatggtttct tatgcacagt ttgatcgaat cggctgtgta
    20821 ggagcaaaac tgttttatcc agatgataca acgcagcatg caggagtatt attaggaatc
    20881 ggtggtgttg cagggcatgc attgaataac tatgatcgaa cacattgtgg ttatttcggc
    20941 cgattggtca ttgacgtcaa ttacttagca gtcactgcag cttgtatgat ggtcaaggca
    21001 gctgacttca atgctgttaa cgggtttgat gaaacattag aagtagcatt caacgatgtt
    21061 gacttgtgct tgaaagttta tgaactgggt cgttacaatg tctatgcaca tcaagcagaa
    21121 ttgtaccatt tcgaatctaa atcaagaggt tatgaagata ctccagaaaa acaaagacgt
    21181 tttgctggtg aaatcaaaaa aatgcaagat aaatggccag catatattgc gcatgatcca
    21241 ttttacaatg ataatttaac aaaagaagga atcggcgact tttcgttgag accagattaa
    21301 actataataa aaagctgtta tgttgtgatt cgctcgcaca taacggcttt ttatagtttt
    21361 ttgtcaaaaa aaggcagaag gtgccgactc aaaaaaataa gtcgaggttg ggacagaagt
    21421 gtttaactcc gagaaataag aagaaattca cgaaaattgc ttttcaaatt tttgtgaatt
    21481 tcggcttatt taagaagaag ttgcttctgc tcccaccgtt tattcgtttt taaagaatga
    21541 gacaaaagtg tttcttactt ttgtcccacg ctcttattca tgctcagagc gccaatagat
    21601 acaaaatcat agccaaagtt tcacgaaccc tagctgtcaa agaatcgata ttttatttta
    21661 atataggcta ttttaaaata aatggtttaa ggtattcctc tacaaaagcc actctatcaa
    21721 ttatcatggg tttaaaataa gaagtgatgg agataaccag attgttctta gcgtcaatat
    21781 aaagaacatt tccactatta ccaattgctg aatatatttc gttctcagaa tctaataccc
    21841 accataaata gccatatctc atattttgta agtcttctaa agcactggtt ctaggtttga
    21901 acatctcgtt tatccacatg ggtggtacga tttgttttcc tttatacatc cctttattta
    21961 ggcataatac accaattttt gccagatcac ttgccgataa acacaaacca tatcctgccg
    22021 tcccgatatt tagtggatca caaaaccaga cattggtttt aggagactta tccattgtaa
    22081 actgcttatg ttcttcagct gtttcagcat aataattgac atggtttggt atccctatag
    22141 gatcaaatag atacttattg gcaaaatcaa cagttgttag cttacttgtc tgatacaaca
    22201 agccagttaa tatgtgtaaa cagacagttt gatagttgaa ttcgccggtt ataccttttc
    22261 ttcctcccaa taaatctagt gatgtttttg tccaatcttc acttgaacag acttttgtcc
    22321 atggatcgcc tttacatttg tagggtgctt tcattgttag caagtgcttg attgtaatag
    22381 cgtaaatagt tttctccccg cgtttcactt tatactctgg aaaataatct aatactttat
    22441 catcgatact tttgattaat ccttgctcta aagcaatgcc aatcagcaaa gatacaatac
    22501 ttttcgttgc tgacatgata tgacaagtat cgtctttttt ataaccattc cattcatctg
    22561 tataaacttc taccccatcc ttatatgcga caatttgaca tatatttggt tgtcgaaaac
    22621 caataaaatc atgcaactct tgtttattca taagatatta cctcactttc ttctataagc
    22681 ataatgtcat taaaaatcga tttcaatttt ttcgattctt cacgtaatac aggtattctt
    22741 atggactaga cagcgctttg ggaagatgga ttctctgaaa aatataaagg ttcactttat
    22801 gagtggataa aaaaagcagc aaatacttcg acttctttaa tttaccaaca ttagtgaaaa
    22861 tcgattcatc tggagatttg taatttagag tccttgtctt gattagaggt gtataaagct
    22921 ttttattaga catttttaaa ttccattaca atttgcttat aaactaggtt tttaaaggtg
    22981 actatggtaa gataatagag atattatttt gt
//
LOCUS       DASHWW010000039        22236 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.039, whole genome shotgun sequence.
ACCESSION   DASHWW010000039 DASHWW010000000
VERSION     DASHWW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.039"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(717..3866)
                     /locus_tag="U2R64_001710"
     CDS             complement(717..3866)
                     /locus_tag="U2R64_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEM8918531.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3880..5124)
                     /locus_tag="U2R64_001711"
     CDS             complement(3880..5124)
                     /locus_tag="U2R64_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEM8918532.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5117..6709)
                     /locus_tag="U2R64_001712"
     CDS             complement(5117..6709)
                     /locus_tag="U2R64_001712"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEM8918533.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7218..7943)
                     /locus_tag="U2R64_001713"
     CDS             complement(7218..7943)
                     /locus_tag="U2R64_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918534.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8097..8423)
                     /locus_tag="U2R64_001714"
     CDS             complement(8097..8423)
                     /locus_tag="U2R64_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918535.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8460..8825)
                     /locus_tag="U2R64_001715"
     CDS             complement(8460..8825)
                     /locus_tag="U2R64_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEM8918536.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8862..9077)
                     /locus_tag="U2R64_001716"
     CDS             complement(8862..9077)
                     /locus_tag="U2R64_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918537.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9206..9541
                     /locus_tag="U2R64_001717"
     CDS             9206..9541
                     /locus_tag="U2R64_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918538.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9617..11614)
                     /locus_tag="U2R64_001718"
     CDS             complement(9617..11614)
                     /locus_tag="U2R64_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918539.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11712..11987)
                     /locus_tag="U2R64_001719"
     CDS             complement(11712..11987)
                     /locus_tag="U2R64_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918540.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12219..12953
                     /locus_tag="U2R64_001720"
     CDS             12219..12953
                     /locus_tag="U2R64_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918541.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12992..14134
                     /locus_tag="U2R64_001721"
     CDS             12992..14134
                     /locus_tag="U2R64_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8918542.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="U2R64_001722"
     CDS             complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="U2R64_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEM8918543.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15625..16095)
                     /locus_tag="U2R64_001723"
     CDS             complement(15625..16095)
                     /locus_tag="U2R64_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEM8918544.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16082..17317)
                     /locus_tag="U2R64_001724"
     CDS             complement(16082..17317)
                     /locus_tag="U2R64_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEM8918545.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="U2R64_001725"
     CDS             complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="U2R64_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEM8918546.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="U2R64_001726"
     CDS             complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="U2R64_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEM8918547.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19583..20431)
                     /locus_tag="U2R64_001727"
     CDS             complement(19583..20431)
                     /locus_tag="U2R64_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEM8918548.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20455..21141)
                     /locus_tag="U2R64_001728"
     CDS             complement(20455..21141)
                     /locus_tag="U2R64_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918549.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21134..22168)
                     /locus_tag="U2R64_001729"
     CDS             complement(21134..22168)
                     /locus_tag="U2R64_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8918550.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
BASE COUNT         6390 a         4551 c         3725 g         7570 t
ORIGIN      
        1 gactaataca ggtagtcctc ttttttgtta ttttgatatt ctaaatcatt ttttattgga
       61 ttattccctt gttcgatata gacccaaatt gatctatcaa taattatcaa actgagtcat
      121 atagagacaa aaatttcaaa aatgacctgt taaatggtca tcgaatatca tttaaaatca
      181 atacgacgga gtcagacacg gagtcaaaac aagcccgctg agagtaaaaa atatatacag
      241 tcccataggt aaagtgccac aggactgtat ttttttttat ttgagattac ctgaaatgat
      301 tccatttact ttttatctca ttttttccta ctagttagta tcaaatactc tcctattttc
      361 tcaataaact attttgggtt acatggtatc tgaaacagct aaaaccttgt cattacagca
      421 aaaaatcact ttatctccgt ttcatttcag atacatttca cttaagcgga ttccaaaaaa
      481 acaaaagaaa aaggaacccc tagttagcct atgcttttta ttggttcctc tcaaaacacg
      541 gtcatataac aacggggtgg ggtaaatgaa tgaaaaaggt ggaggaaaca ttattcaata
      601 gctgtcttaa atacttcgtt ataaaatgtg aacaaataaa agacatctat ccctattttc
      661 tacacttcca ctttactacc atctttgaat cgtacaattt tcttaactct tctcgtttac
      721 ctcaattcat tttcaagtgg aatcagctca tcatctaaca ttttacgcca tgctcgcttc
      781 atttcttgtg ggtatttaaa tggcttcgct tctggatggt tggctttata tccttcgtaa
      841 tccttactgt tgataattgc tttcatatta ggaattggat cttcacctgg catatattgc
      901 agattagaag catgtaattc tttctcagaa acaaaccact cattggaaaa gacatgaatc
      961 aaatcatcac tcgcttgtgt aaaatagcga cgtttaatga caaagatatc ttcattacta
     1021 tctaaagtcc ccacatcaaa cgcatttaaa atttgtcggt aaacttcttt gactccttct
     1081 gttttattca atttagccaa agctttttca atttcttctc gtgcatctga actattcgcc
     1141 gcataagttc ctagtaattg atcaatataa gtagaatcaa tatcatacaa cttcgtggta
     1201 ttttcactat aaaattcgat cgtggaaaaa tcttctccct ctttttctgg ttcttcctct
     1261 attaatgaac ccttcacggt ctcgtacacg ccaatttgtt cttccaaaag ttgaatttga
     1321 ttgttcaagg ttgaagattt caccatgtca tcattgtaat cgtcataagt cactaacgat
     1381 tcataagcac gattcaattc ttggaatgct ttgacgtact cgatacggat ttcaagtggc
     1441 gtatgttcat caatggattc catggatgaa acctctttta acttaccata tgcttgcttg
     1501 aatctttttt tggattcctg ataacttgga taaatcaaac ccgattcttc ttttgcttct
     1561 gaatacagtt ttgtcgcatc ctcgacattc ttctccattg tggctggctt tcggaaagta
     1621 acaattagtc cttttgtttt ttctggatac gtacggttcg tacgtgaaaa agcttggatc
     1681 aatcctgcat actctagatt acgatccaca aatagggttt gaatcgtagg tgcgtcaaaa
     1741 cctgtcaata gacgatccac tacgatcact aaatcaattt gtttcccaaa ttgtttgaat
     1801 tccgctcttt ttcgtgccaa acgattattg atgtctccgt tataacgctc aatgtctgct
     1861 aatgaccagg aagtattata atactgatta tattcctcaa taattttttg catttcttct
     1921 tgttggacac ttgaatctcg gctgttttct tctaatgaat aggtaatagc gattcgtgga
     1981 aaatcaggat cctccatcgt tcttccttca cgaatgggct gattaggaaa ctcttttgtt
     2041 aaccagtcag gttctttcgt catttctttg atcgctcgat aatacttttt ggccatgtca
     2101 atggaactcg tggttaagat cgcagacttc gttggacggc catttcgaaa atcaaatttt
     2161 gtataggcat tgtctggacg gaacatttta tgaatgactt tttggatatg ttcatctgct
     2221 tcaaaaacag tagggtccaa ataactttct tttttgacag gctccatttg atcaatcata
     2281 cgattgatct gttccggtga atactctgca tatgtttcta cttcttttaa tttccgatag
     2341 attttattct ctaatgaagt cggctccacg gtgttttcat gctctacttg aaatcctaaa
     2401 accgagccat cttctaatgc attcttgatg gtataggtat gcaagacctc tccatactga
     2461 tcatgggtcg tacgtgccaa ttgccctttg gcttgtttcc gattctcagg gaaaatcggt
     2521 gtacctgtaa agccaaacca agtggatttc ggaaacattt ttttgatttc ttccatattt
     2581 tcagcactta acgctcgatg acactcatct actacaaaca cgatatgttg ccccattaat
     2641 ttttggaagc gattggttcc ttttttctct tcttgttttt ttgcatattt caacgccgca
     2701 tctagctttt gacgggttgt aataatcaca acatttgcat tggcatctgc caacagagtt
     2761 tcacttaact ctttggcact tcctgttccc acgatcaagc tattcgcttt ggcgttcccg
     2821 gaagaaatcc cagtattaaa ttccgaagca aatttcgtaa actctgtggt ggtttgatta
     2881 tctaaatctt tgcggtccac taacatgatc gtccgatcga tccccgattt tcgtgctaaa
     2941 agcttagtag atacaaaact agtcaacgtt tttcctgaac cagtcgcatg ccacacatat
     3001 cctgattgat gtttatttgc agcaataaac aaggcttgaa tcgcatgtac ttgataagga
     3061 tgtaacacca tgaggatttt attgtcttga tcttcactga caatcgtata atccgcaatc
     3121 aagcgatgag catccgggat atttagcact tgtttgcaaa actcatataa gttttctacc
     3181 tttttattat ctttcgttcg ccaactaaat aaaaacttag gatgcaaatc ctttggtaag
     3241 gcatttgcaa aataccgagt ggtttgttca ttggaaacca caaacaactg taaggtcgaa
     3301 aagatattgt tccgaaacat accttcttct gcatattttt tgatttggtt aaacgcctga
     3361 taaaaactat cttttgcggt tacttgtttc agctcgattt ggacaatcgg taatccattg
     3421 atcagtaagg tgacgtcaaa acgtcgatcc cgtgcttcta tgttacttcc acgttttgca
     3481 atttgatgga ccacttcata ggtagagatt cctccaccaa tgtcttgatt agaataaaga
     3541 atgagcgaga cagaacccag ttgcggatct tcccgttcaa tcgtgatccg agccattcca
     3601 ttttcacctt ttaaccattt cgcagcatca aagggggttt tcgttcgtag taacaattct
     3661 gttttgatcg tttcaaattc tttatcggtc aaaggaaaat cattcagttc tgcttgatta
     3721 tttgagatga ttttttggcg taaattgacc caaagatctt cttctgattt tagatcggga
     3781 cgatacgtcc actgattatg cccttccccc aatacacgga tcaactgttc ttcgacttcc
     3841 gcttcctcac ggtgactaat tttcatttat cttccctccc taaacaaaca tcttttgtaa
     3901 gaagcctttt ttcgtttcct tcagcaaatc taacttacgt tgatgaagag cgatcgtgtc
     3961 gtcgagttgt ttgaagaaag cgccgatttt ttgttgttcc tctttattcc tagtaaaagg
     4021 aaacttgata ttagcgaaat tctcatagaa taagtattct cgtacgcttc cttcagtgtt
     4081 gcgcttgacc tctttgataa atgttggtga cttgataaac tgaagtatga actcattatc
     4141 taagtcctcg ctcattttca caactacata aagagagcta acaatgaccg tcataccaag
     4201 attgttaaat gcaattgatc ctacgtttac tcttgctgga ttataggcga attcatttgg
     4261 ttcaacgaat ttataatttg ttttttctaa atcatccaac ctactaccat caaactgttc
     4321 tgtttgagaa attaaacctg ctttattact taccgaatag gcagggaagt ctaaatcttt
     4381 cgtgttcttt tttccagtct tcttactaaa ctctttgaac ttacgctgtt cccaatcttc
     4441 cgtaaatcca ggaaaccgaa tttctggcac ttttgctccg tttttaggga acattttttg
     4501 taagaatcct tttttcgttt cctttaataa atctagctta cgttgttgaa gagcgatagt
     4561 gtcgtccagt tgtttgaaga agttcccaat tttcttttgt tcttctaata ttggaaattg
     4621 tactatccat tttttcactt ctgacattgg tacgagattt gtaattgctg aacctggatt
     4681 agctcctgtg agttttcttt gcataaaatc tgcacgaata aattgaataa aatattctga
     4741 atctgtgatt tctttattta ttctaagtct aatcaaagcc tgattgaata cacccggttt
     4801 tatttgcttt ggtactcttg aaattctccc aattgttcca gcgccactca tgataaaatc
     4861 gcctggttct aatttaaatt tgattaattc attatatttt ttttcagtaa ttttatatct
     4921 tgtttcgtaa ttatcataaa tagcattttg ttgttcatag acaacaaaat tgctattaga
     4981 tacaaagaat tctttcttta aggcactccc aaatggtccc ctccttactc catctttttt
     5041 atcaagtaag cattcaaact tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat
     5101 ttctggttgt atatcattac tcatgtttga acacctccag cgcaccttgt aaccacgctt
     5161 cattttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt tctagcactt
     5221 gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca attggttctt
     5281 cttcttcaaa cgtatctaca tagcgtggaa tatttaagtt atagtcattt tctttgattt
     5341 catcaaagtt tgccaaatga gcgtatttct cgacatcttt tctttcagca taggtttcga
     5401 ggattttttg aatgttttct tccgataatt tattctgatt ttttcctttg acaaattctc
     5461 gactagcgtc aatgaataat acgtctcgag tttggcggtt ctttttcaat acaatcaccg
     5521 tcgttggaat cgatgtcccg aagaacaagt tcgcaggcat accgatcaca gcataaatac
     5581 tgccgtcttc tagtaatttt tgacgaatga ccccttctgc agcgccacgg aataaaactc
     5641 cgtgtggcaa gacgatggcc atagtccctg tttccttcaa atgatagaaa ccatgaagaa
     5701 gaaacgcaaa atctgctttg gattttggcg ctaattttcc ataacgatta aaccgagaat
     5761 cgtctaagaa ggtcgtatct gctgaccaat tagccgaata aggtgggttc attactactg
     5821 catcaaatgt gtaaggttca tctgttggcc aatccttatt caacgtatcc ccattgcgga
     5881 gattcatttc ttcggcatct accccatgta aaatcaagtt catttttgct agattgtatg
     5941 tcgttgtatt taattcttgc ccatgatatt taacgttatc tgggtgagtt aagtagttac
     6001 gcacatttaa catcaatgaa cctgaaccca tggttggatc aaaaacacta aagaatcgtc
     6061 gttctttttg atccaacgtc acgatttgtg ccatcatatc agaaaccata tgaggcgtgt
     6121 aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga aattcataag
     6181 catccccgat cacgtcccca tcgtgaccta aaacttccac gtcattcaat ttcttaatga
     6241 cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt gattggagat
     6301 ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc acaaaggctt
     6361 tgtttagatc attcaattgg aacgttgctt gttttgcttg atccgctaag acgttgaaaa
     6421 gatactctgg cgaaatcgca taccccaaaa tatcaacgat tgttgcaatc agatcttctt
     6481 ttgattcttc atctgaaagt aattcgcgat acaacatcgt ttgtttgctt accgtatcat
     6541 attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaaacgg tcggataaat
     6601 atttatagaa aatcagtccc aataaataat ttttatattc tgacgcatcc attttgctac
     6661 ggagattatc tgccgcacta aataattttt gatttaattc tgcacccaaa aagatacact
     6721 cctatctctt atttaaagtt gctatatacc ctcttatttt agcatactcc cttttagaaa
     6781 aagcaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa ggagtctaac
     6841 gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta catagttatc
     6901 tttagaacca tttcagatac atatgaaaca attacatatg attttttcat aaaaaaacag
     6961 tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta aaatcactac
     7021 ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc gtttcatttc
     7081 agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca gtagcttatc
     7141 ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt aaataaatga
     7201 aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta atcagttacc
     7261 tgtccgttct taaataccac agaataatct tttttcccat tttcaagtaa ccgaagtgga
     7321 atatctttac caactttctc tgtcactgca ttactgatac ctgttagatt agctaataaa
     7381 tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt gattccttta
     7441 tcttcattta caagtttcca agtaggtggt atagctgtgt atgtttctac aaatgaatta
     7501 agtttttcat taagtgactt ctcttttata tttccatcta aaaactctgt atatatggct
     7561 tgagctatac taaaacaaag ctggccttgt tctaataatt ttacatcatt agttagtaaa
     7621 gctgtgttca cgttatcaat cgcttcaaga agagtatctt tggtgtccct aacagcttta
     7681 ggtgtgcctt ctggaatttc cctacttgat acctcgtcca ttttatcttc cataaacccc
     7741 ttaaaatcat atctttctcc caaatccata gaagtttttg agaaagcttt catttctgag
     7801 tctatttctt caataatatt taacatgtct gatacatatt gtttaggctg attcgttttt
     7861 aatctatatg tggtaaatat ctcaattcct ccaattatca ataaaattgc caaacaaatc
     7921 cataataatt ttttcttttt catttttcct cctatacact gctgttataa cagtgactaa
     7981 tgtaaagatt ttcccagcaa tcatcagact attatttaca gggaatcaaa aaaactcctt
     8041 agtaagctta cacctttagg agttcctgtt tgaacggtat gcataataca tttaaatcaa
     8101 tttaacatta acacctcagt atatggtatc tctacatata cacggtcttt ttttggatag
     8161 tactcgacat ttatattgat agcacttcca ttgtctaacg tagctttagc ccggtacgtg
     8221 ttatcaccat tatcatgagt gatcgtcaca tcatcacatg tccgatttaa gttatactgt
     8281 tcttgtaaaa tctgagttac caatggtaca gatgacttct ctagtccaga tgaacccgtc
     8341 attcttgaaa aaattatacc tataatagcc aatacaacga tacctataat gacaaacttc
     8401 ttattcatat ttactttatt caacttttta tctcctatct ccaaaatgat tttctctcat
     8461 cagtaactca ttgacatccc caatagtaca ccaaagatgg ctccagctac ccctgctatc
     8521 atcaaaatcg tacccatttg ttcatctttc tctcgatata agtaacccat aataacagca
     8581 acagcaccaa ataccacagg aataaatgct aatgatacta ccatagaaat ccaaccaata
     8641 atcaaataca gcttccctgt ctcttgtcca tgtacgattt gttccttcat ttcattaatt
     8701 gtctgctcag tacttttctt tactgtgtct gttccggttg tctcatctgt ttcttgtaat
     8761 gctccgcaaa actggcaata cttactttca tttgttattt ctttaccaca ttttctacaa
     8821 tacatgtctt ctcctcctaa aatcattcaa ttgcttatta gctaactgtt tactttatta
     8881 aatacatcag aaaacagctc atttattggt acacttaata tctcagaaag cattttcatt
     8941 tgatagggtt taggaatcgt tctccctgtt tgccacgaac ttacacattg ctgtgtaaca
     9001 ttcatttttt tggctaactc agtttgggaa agtccttttt cttttctgta tcggctgaga
     9061 ttacttactt ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat
     9121 ttcaactcat aaaatatata aatacttcaa atgtcattac aaatacaaca acttgttgta
     9181 ctctactgag aaggggggtg tattaatgaa acagaagcaa tatgcaaagg tcattagaga
     9241 aaagcgaaaa gcactcgggt ggacacaaaa agaattagct aaaaaaatct tctctacaca
     9301 acaggcagta gcaagatggg aaaattctgt aacagaacct aacctcgata gcttaacagc
     9361 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg acatagatta
     9421 tgaggaagag tttttggctc tctatcgctc tcttagtact gaagatgcaa ttcgaacaat
     9481 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
     9541 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
     9601 gctatggata acctgtctag tttaatataa ttgggtctct tctattcctt actctccgtc
     9661 catcatctct tgttacactt gtaaattgat aaataggaac taattcaact cctgataata
     9721 tcaattcttt tattacttca tctatccctg cccctttcgc tagatatact aaaaaactac
     9781 tgcttgcttt cacattgtat agtttcttaa tatccttaga agctcgttca agagtgaatc
     9841 cttgtttaac aaagtagcct ctgttttcta ttaaagcatt tttcacgctg ttatccctga
     9901 catttcgtag gcgttcacaa acagtgttaa taagttcttt ttctgtcatt agatatgtcc
     9961 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
    10021 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
    10081 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
    10141 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
    10201 agacattgct tctcttatgt ttaaagtttc ctaacgcttt ctcttccttt aacctattta
    10261 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
    10321 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaag
    10381 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
    10441 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
    10501 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
    10561 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
    10621 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
    10681 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
    10741 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
    10801 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
    10861 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
    10921 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
    10981 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
    11041 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
    11101 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
    11161 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
    11221 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
    11281 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
    11341 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
    11401 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
    11461 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
    11521 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tcttgatcta
    11581 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
    11641 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
    11701 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
    11761 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
    11821 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
    11881 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
    11941 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    12001 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    12061 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    12121 cataatacct cgataaaaaa ggggtgtcaa cagctttgta aaatttattt acaacacccc
    12181 ttttttgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    12241 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    12301 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaaa
    12361 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    12421 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    12481 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    12541 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    12601 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    12661 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    12721 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    12781 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    12841 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    12901 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    12961 tactccttgt aaactaagag gagatgattt aatggcaaaa atatcaaagt acaaaaagaa
    13021 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    13081 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    13141 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    13201 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    13261 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    13321 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    13381 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    13441 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    13501 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    13561 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    13621 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    13681 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    13741 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    13801 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    13861 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    13921 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    13981 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    14041 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    14101 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    14161 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    14221 taacaggttt acccaacact gccttccatc tcataactga tcaatcgatt gagttcgact
    14281 gcatattcca ttggaagttc tttggtgaat ggttcaacaa agcccatgac gatcatttca
    14341 gttgcttcag attcggtcag gcctcggctc atcagatagt agagttgttc ttctgagatt
    14401 tttgagactt tggcttcgtg ttctaaagag acttggctgt tgtggatctc attgaatggg
    14461 atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt cacattcgat atgagagatc
    14521 gaacccgcac tgtttttggc aaaggttact tgtcctcgat agtttacttc tccgccgtct
    14581 tttgaaattg atttagagac gatagagcta gatgtatttg gtgcattgtg gatcattttt
    14641 gcacccgtat cttggatttg gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt
    14701 gcaccttttc catctaagta aacacttggg tatttcatcg ttgtttttgc acctaggttt
    14761 ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg ctcgtttggt tactaagttg
    14821 tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta
    14881 aagatttcta cgatggcggc atgcaggctg ttacttgaat aagtaggtgc cgtacaacct
    14941 tcgacatagt ggatgcttgc tccttcgtca acaatgatca gcgtacgttc gaattgcccc
    15001 gtgttttccg cattgatccg gaagtacgtt tgtaatggaa catcgacttt gacgcctttt
    15061 ggcacgtaaa taaaggtccc acctgaccat acggctgaat tcagcgctgc taatttgttg
    15121 tcggttggcg gtacaagttt tgaaaagtac tctttgaata attcagggta ttctttcaaa
    15181 gcagagtcag tgtcagtaaa gacgattcct aacttttcga attcatcttt catattatgg
    15241 tacacgactt ctgattcata ttgtgcggaa gcaccggcta gataagctcg ttcagcttct
    15301 ggtataccaa tcttttcaaa tgtatctttg attttttctg gtacgtcttc ccagtcacga
    15361 gcgggtttgt cacttggttt ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg
    15421 tcggggcccc atgtttgcat tggcattttg ttaaatgttt ctagagattt cagacggaat
    15481 tcaagcatcc attctggttc gcctttgatt cttgacatct cacggatcac ttcttctgtc
    15541 aagccttctc ctgtactgaa aaccggttcg acatcatcgt gaaacccgaa tttatattct
    15601 tctaattctg gtacgcccat gttctcactc ctcttccttg tggtaatgat ggaaagctgc
    15661 ggtaccatcg ttttccattg cttttcctag tgctttccag gcaagtgtcg cacatttgat
    15721 ccgagcggga aatttagcta caccaccaag catagcagca tcgcctaatt ggtcgggatc
    15781 tttgacttct tttccttgga caagctgtag aaagtctaca gttaaatgtt ctgcttcttc
    15841 tattgatttt ccgatgacgg cgtctgtcat catcgaggca cttgccgtac tgatggagca
    15901 gccactgccg tcaaaggcga tatttttgat gattccgtct tttacatcga cttgcaattc
    15961 gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct
    16021 tccacgatga tgcggatggg aagaatgatc caagatcact tgacggtata aattgtctaa
    16081 tttagatagt cccatgttgg aaaaactcct ttgttgccat gattgcttca actaaacggt
    16141 cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg agcagtcgct gatacttcaa
    16201 ggtacttcaa tagcggttgc gcacaatgat gacctgctct gacggctacc ccttccatgt
    16261 ctaaagctgt cgcgacatca tggggatgta acccatccaa attgaatgca acgactcctg
    16321 tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc atcaattgct tgtaattttg
    16381 gcaacacata agcggctagt tcttcttcat atcgatggat attgtccata ccgagttttt
    16441 gcaaataatc gattgcatgg cctaatgcga tagcgccggc gatatttggt gtccctgctt
    16501 cgaatttcca aggtagttct ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt
    16561 cgccaccaaa ttcaacaggt tccatttctt ctaaccattt tcgtttacca tataaaacac
    16621 caatacctgt tggtccgcac attttgtgtc cgctgaaagc aaagaaatca cagtctagtg
    16681 cttggacatc aatggccatg tgcggggcag attgagcacc atctactacg atgaccccgc
    16741 cgttttcatg gacaagttca gctaattctt gaacaggatt gaagacacct aagacattgg
    16801 atacatgagc aatggagacg attttggttt tgtccgtaat ctttttcgct gcatcctcca
    16861 tatccaggaa gccttcttct gttagttcga tatatttcaa gacagcacct gttcgttttg
    16921 ccaactgctg ccacgggata acattagaat gatgttccat gtaagagagc actatctcgt
    16981 ctcctgcttt gatatagcgg tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg
    17041 taccacgagt aaacagcact tctgctgttt cttttgcatg gatgaacgcc cgtacttttt
    17101 ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa
    17161 cattggcgtt atcgtgttcg taatagtacg ctaatgcctg gagtacttgt tttggctttt
    17221 gggtcgtcgc tgcattatcc agataaacta aaggttcatc attgacgtct tgaaataaga
    17281 taggaaaatc attgcgtagc tttttagcat cgatcatcca ttcaacttcc cttcgattac
    17341 ttcgactaat tctttccgaa cttgttctac agggattgct gttaagacag aaccgaggaa
    17401 tcctcgaatc actaagcgct ctgcttcttc tttatgcaat cctctactca tcagatagta
    17461 catttcttct ggatcaactc gtcctacact ggcagcatgt ccagcagtta cttcgttttc
    17521 atcgatcaaa agaataggat tcgcatcacc acgtgcttta tcagaaagca tcaagacacg
    17581 actttcttgt tgggcatctg caccttttgc ccctttcaag atgtggccga taccattaaa
    17641 ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg
    17701 ggctttattg gttactcgtg tatcgattcc ttggatttgt ctgcccgagc tgattgccac
    17761 gattttgact tctgcgtgtg caccttctcc tgctaaatct gagtcaaagt cagcgatcac
    17821 atgaccgtca ttcatgacac caattgccca gtcgacagaa gcatctcgta aaatgtgccc
    17881 acggcgattc atataagaag taatattttc tcctaattga tctacggctg aatatttgat
    17941 ttttgaacca gctttagcga tgacttccac gatgatatta cctgatgatt ttgctacttg
    18001 ttctttggtt gtctggaaac gttccagata agaaaattca ctatgttcat ctgccacgat
    18061 caacacatgc ttgaagaagt gctcatcgga tgcgccatct tgaatgaata aggactcgag
    18121 tggttcatcg atcacgacat ttttaggcac atacaggaaa ataccgctgt tcataaaagc
    18181 tacatggagt gcagtcaatt ggtcttcgtt catgtttact gcttttttca tataatattc
    18241 ttggactagt tctggatatt cgatcattgc agtgaacaag tcggtaaaaa tgactccttt
    18301 ttctgctaat tccacaggca gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac
    18361 aggattgtct ttcattgcat caaatgccgg aatcgtgcct gtttcactga tggtttgtgt
    18421 ttctttcaca tcaaataacg accagcgatg gaatttcacc cgatcgatat gcggcaatgg
    18481 cagttcatct gctttcgcta gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc
    18541 tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg agccagtttt tttctttcat
    18601 tcttgctccc ccttacgctt cttcttcttt atagtcgatt cctaattctt tactgatacc
    18661 agcgtagcct tctgcttcca gacgtttagc taggtcagca ttccctgtca tgactactcg
    18721 gccttccatc atgatgtgaa cgacatcagg tgtgatatag ttcaataatc gttgatagtg
    18781 ggtgatgatc aatgcaccga aattgtctcc gcgcatttca tttactcctt tagcaacgac
    18841 tttcaaagca tcgatatcca gacctgaatc gatttcgtct aaaattgcaa atgtaggttc
    18901 taacatcaac aattgcagga tctcattccg tttcttttct ccgccagaaa aaccttcgtt
    18961 cagataacgt tcagccattt cttctggcat atttagtaaa gccatttttt catctaactt
    19021 tttcaaaaat gccataacag aaattttgtc gttttcatca cgtttcgcat tgatcgctgc
    19081 acgcatgaat tccgcattcg tgatacctgg tatctcactt ggatattgca tagctaaaaa
    19141 taagccaagt cgcgcacgtt catctacttc caagtctaaa acatttttcc cgtcaaacaa
    19201 aatttcgcct tctgttactt catagtttgg attgcccatg atagcggcag ataaggtaga
    19261 ttttcctgtg ccgttaggtc ccatgatggc atggatttct ccggttttca ttgttaggtt
    19321 tacgccttta aggatttctt tttcctcgat cgacacatgt agatttttta tttctaagac
    19381 agacatgcat tataccccca aattctcttt cgttctcact cattttagac taattgagaa
    19441 tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt tatttattat taaacaattt
    19501 tgatttctaa attagaatag gtataaaaaa gatgagaaat aagccattac agacttattt
    19561 ctcatctttt ttgttccata ccttattttg catcagcctt tactggttta acagagccgc
    19621 cccatttgtc tgtgatccat tcttggactt ctttgcggtg aagcacttca atcagttttt
    19681 tgattttgtc actgtcttca tcacctttac gagtcgcaat aatattcacg taaggagagt
    19741 tgtccttttc aagcaatacg gcatcttcta atggattcaa ccctgcgccg taagcgaagt
    19801 ttgcgttgat tgcaactagg tcaccttcat cattttggta cgtagaagct aaaagtgatg
    19861 ggtcgatcgt atggttgaac ttcaagttct tagggttttc ttcaatatca tcgaatgttg
    19921 ctgtttccag atctactcca tctttgactt tgactaagcc agcatcttgt agaattgtga
    19981 tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat tgttgcacca tcttttaatt
    20041 cggaaacatc tttgactttt ttagagtaca agcccattgg ttcgatgtgg acagcaccgg
    20101 cattgacaaa gtcatatcct ttttctttga tttctttgtt caaataagga atatgctgga
    20161 agtaattggc atcaatgtcg ccttcttcca aagattggtt cggtaataca tagtcatcga
    20221 atttgacgat ttcaagatcg attccttcat ctttcaataa tggtttcaca tgttccaaaa
    20281 tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg
    20341 ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg
    20401 ctgctgcaaa tccaaaaatt ttctttttca tatcctacat ccccctatat cctattatct
    20461 tttgtctgtt ttcttagtta agaaatcacc gattccttga acgataaata cgattagtaa
    20521 aataattaaa gtcgcaacga atgtcactgt tagattacca cgctggtagc cttcctgcca
    20581 agcaagacct ccaagtccac ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat
    20641 cgagatcgtt gtaactgtta atccagaaat caatgcggga atactttcag gtatcaagac
    20701 cttccagatg atttcccagt aacttgctcc cattgcatct gctgcttcca gtacaccagg
    20761 gctgacttca cgaaaagcaa tctctactag acgggcataa aatggtgctg cggataaaac
    20821 aagagctgga atggctgctt gcgcacctag catagtgcct acgattgctt tagtaaatgg
    20881 aatgatcaaa accatcagga tcataaatgg cgttgaccgg aaaatattac tgatgatcga
    20941 tacgattcca taaatgattc gagcatacgg tttgtttttg cgtccaatag agtaaaggat
    21001 caatcccaaa actaatccga tgatcgtcac taagaccatt gagattaatg tcatatatag
    21061 tgtatcaagg atagcctgat tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt
    21121 ttctgaaaag cttttatcca cgatggatca cctcaattcc tactccttgt tctttgatga
    21181 acacttctgc ttgatctaat tctttggttt caccagtcat caagacagtc aatgaaccaa
    21241 aggaaccttc tttcacttgt ttgatctttc catacacaac gttgacatcg atgttatagc
    21301 gtcgaatcgc ttgggaaatg actggctcgt tggcatttct ttcgctaaag gtcaaagttg
    21361 ccaaacggcc gcttggattt tctttgatga gttcagctaa tagttctgtc gaatcagctt
    21421 ctggttcgat gtcttgttgt acaaagcgtt tggttacttc ttttttcggt tgtctgaaga
    21481 cagtcaatac gtctccttct tctacgactt tccccaactc catcacagcg actttgttgc
    21541 agattttgcg gatcacattc atttcatgtg tgatcaagac gatggtcaaa ttcaatttct
    21601 tattgatcgc taacaataag tctaatactt cttctgttgt ttgcgggtcc aatgcgctag
    21661 tagcctcatc acaaagcagg atctcaggat catttgccaa tgctcgtgcg ataccgacgc
    21721 gttgtttctg tccgccggaa agttgtgaag gatatgcttg tccgcgtcct tctaacccga
    21781 ctaaacgcaa cagttcttct gcccgttctt tacgtttgct ctttggtacg ccagctaatt
    21841 ccagcggcag ctggatattt tcaagtacag ttcttgacca taacaggttg aaatgctgga
    21901 agatcatacc gattttcttt cggaatgtac gtaattcttt gttttttaat tttgtaatat
    21961 cttgatcgtt tacgatcact tcgccgctcg tgggaagctc aagtccattc aggagacgga
    22021 ctaatgtact ttttcctgcg ccagaatagc cgacgattcc ataaatatcc cctttttcaa
    22081 cgtttagtga aacgtcattg acggcttgga tgtttccgtt tttcccattg aatgtctttt
    22141 tgacattcgt tagttggatt aatgacatgc cattcacatc tttctcttat gatttttcaa
    22201 acaaaaaagc cttcgccctc ttgccttaag caaaag
//
LOCUS       DASHWW010000040        22220 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.040, whole genome shotgun sequence.
ACCESSION   DASHWW010000040 DASHWW010000000
VERSION     DASHWW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.040"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            172..516
                     /locus_tag="U2R64_001730"
     CDS             172..516
                     /locus_tag="U2R64_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEM8918551.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="U2R64_001731"
     CDS             517..936
                     /locus_tag="U2R64_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEM8918552.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="U2R64_001732"
     CDS             complement(1028..1378)
                     /locus_tag="U2R64_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918553.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="U2R64_001733"
     CDS             complement(1344..2675)
                     /locus_tag="U2R64_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HEM8918554.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="U2R64_001734"
     CDS             2931..3497
                     /locus_tag="U2R64_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8918555.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="U2R64_001735"
     tRNA            3642..3729
                     /locus_tag="U2R64_001735"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            4063..5037
                     /gene="bsh"
                     /locus_tag="U2R64_001736"
     CDS             4063..5037
                     /gene="bsh"
                     /locus_tag="U2R64_001736"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEM8918556.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5362..7257
                     /gene="asnB"
                     /locus_tag="U2R64_001737"
     CDS             5362..7257
                     /gene="asnB"
                     /locus_tag="U2R64_001737"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HEM8918557.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNETIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7452..7898)
                     /locus_tag="U2R64_001738"
     CDS             complement(7452..7898)
                     /locus_tag="U2R64_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEM8918558.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8126..8275
                     /gene="rpmG"
                     /locus_tag="U2R64_001739"
     CDS             8126..8275
                     /gene="rpmG"
                     /locus_tag="U2R64_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEM8918559.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8363..8881
                     /locus_tag="U2R64_001740"
     CDS             8363..8881
                     /locus_tag="U2R64_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8918560.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8958..9914)
                     /locus_tag="U2R64_001741"
     CDS             complement(8958..9914)
                     /locus_tag="U2R64_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8918561.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10080..10886
                     /locus_tag="U2R64_001742"
     CDS             10080..10886
                     /locus_tag="U2R64_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918562.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10883..11872
                     /locus_tag="U2R64_001743"
     CDS             10883..11872
                     /locus_tag="U2R64_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEM8918563.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11869..12873
                     /locus_tag="U2R64_001744"
     CDS             11869..12873
                     /locus_tag="U2R64_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEM8918564.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13005..13547
                     /locus_tag="U2R64_001745"
     CDS             13005..13547
                     /locus_tag="U2R64_001745"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEM8918565.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13567..14265
                     /locus_tag="U2R64_001746"
     CDS             13567..14265
                     /locus_tag="U2R64_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEM8918566.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14286..14498
                     /locus_tag="U2R64_001747"
     CDS             14286..14498
                     /locus_tag="U2R64_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEM8918567.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14498..15460
                     /locus_tag="U2R64_001748"
     CDS             14498..15460
                     /locus_tag="U2R64_001748"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEM8918568.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15478..15873
                     /locus_tag="U2R64_001749"
     CDS             15478..15873
                     /locus_tag="U2R64_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEM8918569.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16036..16401
                     /locus_tag="U2R64_001750"
     CDS             16036..16401
                     /locus_tag="U2R64_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HEM8918570.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16398..18209
                     /locus_tag="U2R64_001751"
     CDS             16398..18209
                     /locus_tag="U2R64_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HEM8918571.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18271..18438)
                     /locus_tag="U2R64_001752"
     CDS             complement(18271..18438)
                     /locus_tag="U2R64_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEM8918572.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18686..19675
                     /gene="galE"
                     /locus_tag="U2R64_001753"
     CDS             18686..19675
                     /gene="galE"
                     /locus_tag="U2R64_001753"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEM8918573.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19687..21171
                     /gene="galT"
                     /locus_tag="U2R64_001754"
     CDS             19687..21171
                     /gene="galT"
                     /locus_tag="U2R64_001754"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEM8918574.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21195..22175
                     /locus_tag="U2R64_001755"
     CDS             21195..22175
                     /locus_tag="U2R64_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8918575.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
BASE COUNT         7210 a         3806 c         4619 g         6585 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat aatagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatcaacga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
     3781 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     3841 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     3901 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     3961 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     4021 aagataaaag tgtaaaaacg atttgtttta ggacgggaaa cgatgtgtac cgcaatcact
     4081 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     4141 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     4201 aaacattatg caatgatagg aatagcagct ggggtatcca actatccact ctattatgag
     4261 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     4321 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     4381 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     4441 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     4501 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     4561 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     4621 ctatcaaatg gaacaccaga aaatcatttt tcaaaccaga tcagcttgaa tgtttatagt
     4681 cgtgggatgg gaggattggg cttacctgga gatctctctt ctgtttctcg atttgtaaaa
     4741 gccacattta ctaaaatgaa tgctgcatca ggtgattcag aatctgaaag tatcagtcaa
     4801 ttttttcata tactaggctc agtcgagcaa caaaaaggag tatgcgatac tggagaaaga
     4861 aaatacgaat atacgattta ttcttcttgc tgtaacgttg ataaagggat ttattattat
     4921 cgtacgtatg aagacagtca aattactgct gtaaatatga ataaagaaga cttggatcgt
     4981 catgaattgg tcagttatcc agtcataaaa gagcaacaga taaactatgt caattaatta
     5041 atgaatagat ccgtttggta tcatattttc tgatacagtc ataattagac acgatcttta
     5101 ggtcgtgtct ttttttgctg gtttttttgg aaatagcatc cactaatatt tttttaacac
     5161 gaagagaata aggtagcctc aaaaaagaaa acatggtaaa ttagatattg ggactttatt
     5221 ttctgtaaaa acagaaactt tcatcttttg ttttcacgtg acgaaattgt aagagagaaa
     5281 atattcgtcc gctatttatt ctatgataag atgcatatga atgaaataaa cagtaatttt
     5341 atattaggat gtgaaagtta aatgtgcggt attgtaggtt ttgttaacga caaggacaac
     5401 aaaaaaacaa ttattaatac aatgatggat cgaatcgttc accgtggacc taatagttca
     5461 ggagaatata tcgataaaca tgttgcttta ggattcagaa gattaagtat tattgactta
     5521 gagggcggta ctcagcctat ttacaatgaa gatcggacaa agatcattat ttttaatggc
     5581 gaaatctata attaccagcc tttgagagaa gaattgattg cagctggcca cgtttttcaa
     5641 acacatgcag atacagaagt ccttttgcat ggttacgaag aatggggaac agaattattg
     5701 caaaagatcc gcggaatgtt tgcttttgct atttgggata atgaaaagaa tgagttattc
     5761 ggtgcaagag accactttgg gatcaaacca tattattatg cagaaatgaa cggaacattt
     5821 atgtttggtt cagaaatcaa aagttttctg cctcatcctg attttaacaa agaattgaac
     5881 aaagaagcgt tgaaacctta tatgactttc caatattctc cattaaacgg cgaaacattc
     5941 ttcaaagatg tctatcgttt gcctgaaggc cattattata cgtataaaga tggaaaaata
     6001 gacattcagc aatattggga tgcagatttt gaaacaaaag aaacgcattc ccgacaagaa
     6061 tggatcgaaa aaatcgacga aaccgttcaa gcttctattg aagcacatac ggtcagtgat
     6121 gtagaagttg gttctttctt atccagcggg gttgattcca gttatgtaac ctctgtattg
     6181 aaaccagatc attctttctc aatcgggttt gatgataaaa cctataatga aacgattgaa
     6241 gccagaaaac taaccgaact attggactta gataatacag cagcagtgat cgacggagac
     6301 atgtcgttca aagcattccc tttgatccag tatcacttag atgaacctga ttcaaatcct
     6361 tcttgcgtac ctttgtactt tttagcaaat cttgcttcac aaagtgtgcg ggtagtccaa
     6421 tctggagaag gggcggatga actgtttgcg ggataccaaa cgtatggatt ccatacgaat
     6481 tcaaaattca tccgtgtgat tgctcaagga ttgaaaaaat taccaaaagg aacacgctat
     6541 aatttaggac gtaaaatcgg aaaaatgaaa aatttccatg gacggatcca tttatatgaa
     6601 tcacttgctc ctgcaaaaga atattttatc ggtcatgctc gagtgttcga agaatcagaa
     6661 gcatcagaag tgttaacacc aaaatatcaa acagcaccat ctgtggatga aatcatgact
     6721 gttcattacg agaaaacaga aggaatcaaa gatgaagtca ataagatgca atatgtcgat
     6781 cttcatcaat ggatgccaaa agatatcttg ttaaaggcag ataaactttc tatggcaagt
     6841 tctttggaag tccgagtacc tttattggat atcgaagtca tgaaattggc tcaacaaata
     6901 ccaagtaagt ttttattgaa tcaaaacaac acaaaagata ttttcagaca agctgcgaac
     6961 aaacatcttc cggaagaatg gtcgaatcgt gtgaaattag gattccctgt gccaatcaaa
     7021 gcttggttga aagaagaaca cggctacgaa caagtcaaag cattattcga agcagatttt
     7081 gcaaaagaat tttttgatca agaaaaaatc atgaagttgc tagatgacca tcacgaagga
     7141 cgtaaagaag agcaaagaaa aatctggaca atcttcagtt tcttgacatg gtataaagtc
     7201 tactttgtag atgaaacgat tccgcaagca gaagcaatcg actatgtgac tgtttgatga
     7261 aaatcaaata tcaataaaaa agaggttttc tcctaccgtt taacactgag tgataagaaa
     7321 caatttcaaa aaacagctct tcccgtttta tagatattat gacttatggt tcggagttgg
     7381 cagaggaaca ccattgtttc gaacataagg gggttgtgac acgattttcg tcacaacccc
     7441 tttacatatg ttcaataatc gatttctttt tcttttgtcc catctttttt ataaatgaac
     7501 aaagttgatt ctttgttttg tgctacttgc tttccttttt cgattgcttc tttttttgta
     7561 tcaaaatggt tgcttgcctt ttttgcccct ttagatttca cgatccattg ttcttcctca
     7621 tattctacga tcacatctga atcaagcagt tttccagcac gaggattcgt atcgtgttca
     7681 tccgtcttgc ttggattttt ttctttttcg aaagttcgtt tttctgattc actagcatct
     7741 tcataccatt tttttgcttg atcaatggca attgggatcg cacggttatc agggtaccct
     7801 tcatctaata atgcatttgc gatgtcgatt gctttttttc ttgtcaattt atctaagttt
     7861 ttcattgatg caggaaagtc cttcatgttc catggcatat tagtatcccc ctttattaaa
     7921 aaacataatc tatataaaca agtgtaaggg tatttataca aaaagaaaaa gattttgttt
     7981 gagaagtaaa accgttgtat ttatcgtcaa gtagttttac ttaacaaaat cgtgaaaaac
     8041 actagcaatc tagaaaaaat catggtaaga taatcaagtc tgagagtcat cttagaggat
     8101 tcttgtaaaa atgggaggga aaaacatgcg cgtaaacatc actttagagt gtacttcttg
     8161 taaagaacgt aactatctaa caagcaaaaa caaacgtaac aatcctgatc gtttggaaaa
     8221 acaaaaatat tgcccacgcg aacgcaaagt tactttgcac cgtgaaacaa aataatgttt
     8281 ttaaagttct caattccttg ctggtcaaag aattgagact ttttttatct caaaacatct
     8341 aaaatcataa ggagcggata atatgtttat ttccatgtgg gcacaagata aaaatggtct
     8401 gatcggcaaa aatggtttgt taccatggcg attgccaaat gatatgcgtt tctttcgcga
     8461 acacacaatg gatcgaattt tagtgatggg aagaaagacc tatgaaggaa tgggggatct
     8521 ttcacttcct tatcgccata tcatcgtgtt gacaacgcaa ccaaattttc gcacgaaaga
     8581 aaatgcggaa gtaatgcatt cgatcgatga acttttgtcg tatagtcaaa cgatctcaga
     8641 agatatctat gtttcgggtg gtagtcggat ttttcaagaa cttcttcctt acactggtcg
     8701 gatctggcga acattgatcg atagcacgtt tgaaggcgat acgtatattg ggaatattga
     8761 tttttcagac ttcgccctta tagaggagta tgaggggata acggatcaag aaaatctata
     8821 tgcccatcgt tttcaaaaat gggaaagagt aaaaaatagg gttgcttcaa aagaagaata
     8881 aaatctatgc gtctagtttg ttaataagaa aaaaagcatc tcacgactaa tcgtgaagat
     8941 gcttttttta gttaaaatca atttagtttt tctttgatat cattgaccat ttcctgactg
     9001 gcaataggtc cgttatatag ccaactagat tcaggtccga attgcagtac atgattgtct
     9061 gtcactgctt ttagattctt ccagcttggt tcattgaaca tggcagcatc tttgtcactg
     9121 ttcacaagga tgatgtagtc agcatctaat tcagctagct tttcagagga aacagcagac
     9181 cagtcagaag tggctttttt ggagacctct tccactagat caggaacacc aaattccaga
     9241 tcgtcgtata cgattcttcc acttgaccga tttttgctga ccataaaggc tgagttgttg
     9301 gtcacccaca acactgcagc tgtcttgttc tcgattttat ctgctagttc ttctcgagtt
     9361 ttcttgatgg atttttgata atcggaaatg attttttctg cctctttttc ttttgccaaa
     9421 gctttgccga catcttttag ttgttcttcc catgtgacat ctgttccgtt ttttacaaca
     9481 taagttggcg cgattttgct atattgttcg tatttcccgc cttcgacagt agcggaagaa
     9541 gaaatcaaca gcaaatcagg ctcaaagctt aacactttct cataaggaag gtcataagaa
     9601 atcgttggga catcctttaa atcatcttgc agataatctt gaatggaacc actgccaaca
     9661 gtccactggg cgataggttt ttcccctagt gcaatcagat agtcttctaa gtaactgccg
     9721 atgatccgtt tgggcgcgtt tggaatctct actttatgtc caagtgtatc tgtgactgta
     9781 tgagtactat tggatgaagt cgtcgaattg gcagttgtag ctgtttcttt atctgaagag
     9841 ggggagcaag cgctcagtac tccagccagc agcaatatgc tagataatgt gaatactttt
     9901 gtttttaatt tcatttcttt cctcctaaca taattgagaa tctttctcat tggttattat
     9961 tcctgatatt tcgaacgctg tcaaccgctt catttggcta tagatatgaa agtagcgctt
    10021 gacgaaatgt tgaaacagcg tcataattga gaatgatttt cagcgaaagg atgggtgaaa
    10081 tgacgagatt aagagcagct gacattgcag ccggctacga aaacaaaaaa atcattgaaa
    10141 acatgtctgt tacgattcct gaagggaaaa tcactagttt gattgggcca aatggaagtg
    10201 gaaaatctac tttattgaaa agttttaccc gtatactacc tgtgaaatca ggaaagatca
    10261 ttgtcaataa ctctgatatc tctacataca gttcaaaaga acttgcaaaa aaaattgcat
    10321 tattagcaca aactagtgaa caccctacag gtatgacagt agaagaagta gtatcttacg
    10381 gacgataccc ttatcaaaaa ctgttcagtg gcatggacac gcaagatcat gaagcaattg
    10441 agtgggcgtt ggatgctaca ggtctagctg gatttcgtat gcgggatatc gcaacgctgt
    10501 ctggtggaca aacccagcgt gtctggatcg ctatggcgct tgctcaggaa acagatatct
    10561 tgatcttgga tgaaccgaca acatttttag atccggcaca ccaattagag atcctacagt
    10621 tattgactga aatcaatcaa atgaaacaaa caacgatctt gatgtcgatt catgacatta
    10681 atcatgcttc acgtttttca gattatttat tagcaatgaa aaacggtaag ttgatcacag
    10741 aaggtacacc tgaagaagtg atcacaaaag agtgtatgaa aaaaatattt gagattgatg
    10801 caacgattgt cacgcttcca agaacaaata aaccagtttt tctaacctat gatttgttgc
    10861 caaaagagca ggaggatcaa ttatgaggac tatgaagaaa aatagactcc tgcttttggt
    10921 ctgttttgtt cttttgatta ttttttttgt tgctctttca aatggcgcag cgactgtggg
    10981 aaaagcagat ttttggcagg cgttgtttga ttttgataga tcaaaacaaa gtcaccaaat
    11041 catacgaaat attcgtttgc ctcgtgtggc gggagcattt cttgtaggga gttgttttgc
    11101 attgagcggt gcattgatgc aaggagtgac aagaaatcct ttagcagatt caggcttact
    11161 aggaatcaac gcgggtgctt cgttggcaat ggcccttagt tttgcttttt ggcctaaagc
    11221 ttctgatttt tctgtgtttc taatgtcatt ggcaggttct tttgctgtaa ctttgctcgt
    11281 atttggtttt ttgcagtttt cgaaaatggg catgaatcct ttacagctga ttttagctgg
    11341 cgtagctatt agttcttttt ttactgctat cagccaagca cttacccaat tctttaatct
    11401 gcagcaggat cttgcttttt ggtttgtagg cggagctgcc aatatcacat ggaaacaatt
    11461 agcagtattg tttcctttat atatacttgc tgttttggtt tctttttcat taggaaaagc
    11521 aatatctttg attcatttga gtgaaacaca tgcattagct cttggaagtc atcctaaacg
    11581 aacgcggttg attgttttct gtctagttgc agtgttagca gccattgccg tttcgttagt
    11641 cggacctgtt tcatttattg ggctgttggt tccgccagtt gttcgcggaa tggttggaac
    11701 ggactatcgt tatgttctac ctgtctcttt tttagttggc ggtggattgg ttatgttggc
    11761 ggattttaca gcgaggatga tcaatccccc ttttgaaaca ccttttggat tagtcattgc
    11821 attgattggc gttccgtttt tactgataca agtaaggagg gaacaacggt gaaaaaaata
    11881 tattggacgt tctatttctt gctttttgta cttgtcatcc tgtctatagg tagtttaatg
    11941 attggtacgc cttttattta cctggatcag ctttttgcca cgttcatagg gaaagaatca
    12001 tcttctttgg cgctgattgt tagagaattt cgagttcctc gattactgat cagtttatta
    12061 gcaggagctt gtcttggcgt ttctggttat atcttgcaag gagtaacaag aaatgaattg
    12121 gcagattcta gtatattggg cattaatgcc ggagcaggat ttttagtgat gctttattta
    12181 ggtttctttt cgcactattc gctgccgttt ctattgctag ttgtagcctt tctaggtggt
    12241 gttttagctg cttgctgtgt ctatcttgcg gcctatgatc gaaatggctt tttgggtatg
    12301 aatcgaatct tattgtccgg tattgccgtt aatgccggcc tttctgcatt aacattgcta
    12361 tgcacgatcc aattatctaa ggaaaattat ggatttgtga atgcatggtt agcgggatca
    12421 atctggggtg cgagctggcc ttatgtttgg gcattgcttc catgggcggt tatcttaatt
    12481 ccgctaggag gactttatgc acagaggatt gtattgctat catttggtca agaacgcgcg
    12541 caaggattag gccttaacgt ggctaaaagt caaaaaatcc ttttgttgtt agctgttgct
    12601 ttggcaagcg gtagtgtagc ggtgacaggt agtttatctt ttgtaggact actagctcct
    12661 catgctgcga agctagtcgt acgtaaagaa aataactgga cctttgttct gagcggtttg
    12721 ttcggttcca tttttctgct tagtgcagat atggttgcta gagtgattct actaagtggg
    12781 gaagtaccta caggaatttt gattgccctt tttggtgcgc catattttct gtatgcactt
    12841 tttatcagac aaaaacacgc gctgaacagt tgaaattcat taaaaaagga aggccaatca
    12901 tttctaggtc ttctttttat tctatttatg catttatttg aaagttcgat tgctattttt
    12961 ctttttttcc tataccattt tatgagagaa ggaagggtga gtttttggac caattgaaag
    13021 taagattacg ccggaaagga atcgaaaagc tgaaaaatct ggccaaaagt ggcaagaaaa
    13081 aggaaaaaga acagcgaatc tataaacagc tattcgccag cgagtactgg aagtcagcaa
    13141 aagtgatagg gacgacttta tcgaatgaat ttgaactgga tacacagccg gttatccaac
    13201 gagcagaaaa agaacaaaag aaaatagttg tacctaaaac tttgccgaaa cgtcagatgg
    13261 cgttttatga aatggatgaa cagtccgttc ttgtacgttc gagttttggt gttcttgagc
    13321 cacaatcaga gaagctctat ttgccggaga tgatcgatct cctcattgta ccaggtatta
    13381 tctacaatag agccggttat cgaatcggtt ttggcggtgg ttattacgac cggtatttaa
    13441 ataattttca taaaaaaaca tgtagccttg tttttcgtga acaattgaat gaacaatggc
    13501 aaccggagag ctttgatcag aagatccaac aattgtttat tgactaaaat gaaatgggag
    13561 gttttcatga attatcaaca gcaaataaaa ttgcgtgcat ggttaagacg accgttatgg
    13621 acctatgctt ttttagggat acagacagcg gtcttcctca tgatggaatt atttccgcga
    13681 cttgagatcc cttattatgc cggaatgtat ggtccttatc ttgttcactt caatgaatgg
    13741 tggcgtttag tgacaccaat cttcatccat tttggactga tgcatttcgt aatgaactca
    13801 ctgatactgt attttatggg gcagcaaatc gaggcaatct atggccattg gcgttttttc
    13861 ttgatttata tgttcagcgg gataatggga aatacagcaa gctttgcttt taacgaagcg
    13921 aatgttctgt ctggtggtgc aagtacttcg atattcggtt tgttcggtgc gttgtttatc
    13981 ttagggtttc attttaaaca taacccagcg atccagcagc tagtcagaca ttttctttta
    14041 tttattgtgt tgacatttgt ttttggtctt ctggatacct ctgtagatgt ttggggacat
    14101 gtcggtgggc taattggcgg attagtgtta gggaatgttt tgggtctacc gaaacaacag
    14161 acaagctatt cgatacacca aaggattctt tctacactag tttttgtatt tctttttgta
    14221 atatgtattt tactgggttt aaaaaaatat ggtttacttg tataatatga aggaagtgct
    14281 taaagatgga gagcttatat gatgtacagc agctgttcaa aaaatttggc atctttatct
    14341 atgtgggtgc acgcatctat gacattgaat taatgactat cgaattgcgt aatctgtatg
    14401 atagccgttt gattgatcat gatacataca tgacagcgtg gcgcatatta aaaagagagc
    14461 accgaattga agaaagccga aagaaaggaa atttgtaatg gacaagaaga ttattgggat
    14521 tgatttaggt ggaacaacag caaaatttgc aattttaaca ccagaaggag agattcagca
    14581 aaaatggagc atcgatacca atattttgga tgatggtaag catatcgttc ctgaaatcat
    14641 tgaatcaatc aatcatcgtt tgaatttata taatatgaaa gccgaagact ttatcggaat
    14701 cggcatgggt accccaggaa gcgtggacag cgaagctgga acggttattg gtgcgtataa
    14761 cttaaactgg acagaagttc aatttgtgaa aaaactgatc gaggcaggaa caggaatcaa
    14821 attcgctatc gataatgacg cgaatgttgc tgctttaggt gaacgatgga aaggtgctgg
    14881 agaaaacgat ccagacgttg tattcgttac tctaggaaca ggtgttggcg gaggtatcgt
    14941 tgctggcgga aatttgattc acggcgtgag cggagctgga ggagaaatcg gacatatcac
    15001 tgtggatcct gaagggttcg aatgtacttg cggtaaacgc ggatgtttag aaactgtatc
    15061 tagcgctaca ggtgtggtac gcctaggtcg tttcttggca gaagaatacg caggggattc
    15121 aaaactgaaa gcaatgctag acaacggaga agaagtaaca agtaaagata tctttgaaat
    15181 ggctcaagaa gacgatccgt ttgcattgat ggttgttgat cgcgtatgct tctacttagg
    15241 tttagcttgc ggaaacttgg ggaatacatt aaatccgtca agtatcgtgt taggtggagg
    15301 agtatcggca gcaggagaat ttttacgtag ccgtgtagag aaatatttta aagaatttac
    15361 tttcccgcaa gtaagagaat caacaaaaat caaattagca gagcttggta atgaagctgg
    15421 tgtcattggt gctgcctcat tagccttgaa atttgcttaa aaaaacggag gcattacatg
    15481 gttttatggg taattaatat cattttgcta ttgattgtgc ttgcaatcat cctttgggaa
    15541 gtctatctac gagtaatggc caaacgttca gcaacgactt tgacagaaga agaatttcga
    15601 gaaggaatga gaaaagcaca agtaatcgat gttcgcgaaa aagatgtgtt tgatgctggg
    15661 catattttag gtgcaagaaa catcccttac actgttttga aagattcatt aggatctatt
    15721 cgaaaagacc agcctgtcta tatttacgat caaaagaaaa gtttgagcat ccgtacagca
    15781 aataaattac gtaaagcagg ttatcaagag atttatttac ttaagggtgg atatgacgga
    15841 tggtctggaa aaatcaaaag taaaaaagta taaaacagat gattgtatga cagctttaaa
    15901 aaccgaatca atcattagat tttgaccaag atcacatgaa cggcgcaatg gatagttgtg
    15961 ccgttcattt tttttatttt gtgctattat ctacatatat aagctaagcg aaaaggtaga
    16021 aagaaggaaa caactatgat caaattaaaa cgtgtttacc ttgatgctga aaaagaggat
    16081 ggctatagaa tactcgtgga tagattctgg ccacgaggaa tttcaaaaga aaaagcgcag
    16141 ttagatctgt ggttgaaaga aattgcacct agtaatgaag cacgcaaaac ttttgaccat
    16201 gtaccagaac gatttgcttc atttgcaaag aaataccagc aagaattgat tttcgaagaa
    16261 gaaaagaagc aagctatttt taaactcagt caacttatga aagaacatcc agtcattact
    16321 tttgtttatg gtgcaaaaaa tgaacatcag aaccatgctg ttttattgaa aaaatttatc
    16381 gaaatggagg catgcaaatg aaaataggga tcattggtgc cggacctaga ggattaagtg
    16441 tagcagaaag gattctccat aataatcagg acagacattc tcttgaactt tttcttttcg
    16501 atcccaatgg tcctggaggt cgagtttggc ggttgaatca gccaccggag ttattaatga
    16561 attctgtttc tcaacaagtg acgcttttta cagatgaaac attgtccagt ggaggattgg
    16621 taacacaggg acccaacttg tttcaatgga gtaaaggacc tgctacagat tatatcgaac
    16681 agacggtaac caaaaataag caactaatta tagaagaaat caatcgtctg gaaaaagatc
    16741 agcaatctac tcgatgttta tacggactct atcaacgctg gtttttctca aagttgcaag
    16801 aagaatttcc agcttctatt cagtttgttt attctttagt aaaaaaagta agcaaaagaa
    16861 aagatggtta tcttttacag acagatcagc aaagctattc tatcgatcag cttgttttag
    16921 caagcggtca ctgggaaaat gatgagacag aagaagaaag agtgtgggta gactacgcaa
    16981 agaaaaatgt tttactgtat cagcttcctt ctaatcctgc agatgtagat ctttcgaaga
    17041 taccgcctaa agaaaatgtc tttttaagag gtctaggctt aagttttttt gattatgtcg
    17101 gattgtttac agtatcaaga ggagggcgct tcgagaacga aaagggaaaa ctggtctatc
    17161 atccatcagg caaggaaccg attgtataca gtggatcaag aagggggctc ccttattacc
    17221 ctcgaggaag aaatcaaaag caaggcggag caatggcatg gccacggtta ctaacaaaag
    17281 aaaacctgga gcaatggcat cagtcgggat ttttgactgg cgaaacattt tttgactatc
    17341 tgaaaaaaga cgttgagttg ttttattaca agaaaatcat cgaagaatat cacttgccga
    17401 ttccaaagaa aaattttgag catgattttc tctccctctc ttcagaggag tgtctcggaa
    17461 agcatccagc actaatccct tatagatggg attggtcgta tttagaaact cctcttgcct
    17521 atcagaatga gcccttttca gaagctagcc gaatatttat tgaagggcag ataaaagaag
    17581 cggaaaaagg caattgcaca ggagcatttg cttcaacatt tgatgcatta aaagactggc
    17641 gtgatccaat ccggcaggct attgaatggc acgttttttc tgctaaggaa tacaaagaaa
    17701 tactatgggg atggtttact catctaaata gctttttaac gatcggtccg ccaatcattc
    17761 ggacgaaaga attagcagca ctgatagatg cgggtatttt tcatttgatc gaaccgccat
    17821 ttgatattca gcaaaagcac aaccgctatg ttatttctct acaagataaa gaaatcagca
    17881 gtcgctattt gattgaagct cgattgccac aaacaagctt ttctcgttca agtaatcctg
    17941 tcataaaaaa tttgaaggaa aacaaacttg ttcgcccttt ttcattttca gataatacag
    18001 gaagttatca ttcagaagct atagatgttg agcgaggtac gaatcgcgtg attgatgctt
    18061 caggggaaat ccagtctgac ttttattgct atggaatacc tgttgaaggt gtggattggc
    18121 taactgcagc agtagctaga ccttatacag atccatggaa tctgagacag gcagataaaa
    18181 tagcacaact tatattgact gacaaataaa aatacgcatg atgacttatc tgttttttag
    18241 aaagtcttca tgcgtatttt taaataatta ttaacgagaa acgcgtttac gcattgcttt
    18301 tttacggttt tcttcgatca ttgcttcttt ttcgtcaatt ggatcgatca ctgttttttt
    18361 cacagaagca accaaaccag caacggcagc ggctgttgcc agacttccta ctaatattcc
    18421 agatacaaat tttttcattg aatccacctc atttattatt tgttatatct attatggaac
    18481 aaaagagaaa aaaaggctag ttttacgttt gtttgtaaac ctttgcaaaa aatccttgaa
    18541 aatgtttact aaatgtttta ttataaattt accatatgaa tttacgaaat tttactttgt
    18601 ttgttttcac cataaaagta aacttcgttt tttaaattat atagaatcaa caaacacaat
    18661 tttactaatc aaaggagtgt tttttatgac aattttagta ctaggcggag ccggttatat
    18721 cggttcgcac gctgtagacc agctagttca aaaggggtat caagtagctg tggtagataa
    18781 tttgctcaca ggtcacaaac aagcagtaca tccagatgct catttttatg aaggagacat
    18841 ccgggataaa gaatttctac gttccgtatt tgaaaaggaa ccgattgaag gagtaatcca
    18901 ttttgctgca agctctttag taggagaatc tgtcgaaaaa ccattgatgt atttcaacaa
    18961 caacgtatac ggtatgcaaa tcttacttga agtcatgcac gagttcaacg tgaataaaat
    19021 cgtattctct tctactgcag caacttatgg agagccgaaa gagtctccaa tcacagaaga
    19081 tacaccagct aatcctaaaa atccgtatgg tgaaagtaaa ttgatgatgg aaaaaatgat
    19141 gaagtggtgt gaccaagcat atggcatgcg ctatgtcgct ttgcgctact tcaatgtagc
    19201 cggagcaaaa gcagatgcat ctatcggaga agatcataca ccagaaacgc atcttgtccc
    19261 aatcatttta caagtagctc ttggtcaaag aaaagccttg gctgtttatg gagacgatta
    19321 tgatacacca gatggaacat gtatcagaga ttatgttcaa gtagaagatt tgattgctgc
    19381 acatatttta gctttggaat acttgaaaga aggaaatgaa agcaacttct tcaatttagg
    19441 cagcagcaaa ggatactcag tcaaggaaat gctagaagca gctagagaag tgacaggaaa
    19501 agaaattcca gcagaaatag caccaagaag agctggagat cctagccgat tagtcgcttc
    19561 aagtgaaaaa gcgagagaga ttctgggctg gaaacctgaa tacacagata tcaaagcgat
    19621 tatcaaaaca gcatgggatt ggcatgtcag ccatccaaat ggttatgaag aataggggaa
    19681 tgagatatgt caatcagtca aacgatttgt gattttgcca cacttgcgat cgaagctggc
    19741 ggatggatgg aaatggaccg cttatattta cagaatcgtc ttttagggat ggtaggagaa
    19801 gatgctctag aaagcattga agtaagacca gttaaggaag aatctgtaga cttattggat
    19861 cagcttgtcg ctaaggcaag agaaaatggt gttctttcag aattgccagc agaacaagag
    19921 atttttgaag cgcaattaat ggattttctc acaccgccac cttcagtcgt caatgcattc
    19981 tttgcacagc actattcgaa aagcccagag gaagcaactg agtatttctt taatttaagt
    20041 aagaaaaatg actacatcaa aacaagagcc atcgcaaaaa acatcaaatt tccggcagag
    20101 tcggagtatg gtgaactgga aatcacaatc aatttatcta agccagaaaa agatccaaaa
    20161 caaatcgcag cagaacgcga ggcggtaaaa gtagactatc ctacctgcat gctttgcatg
    20221 gaaaacgaag gatatagagg tcgcttgaac tatccagccc gcaccaatca ccggattatt
    20281 cgaatgaatc tagacggtga aagctgggga ttccaatatt ccccttatgc ttattacaat
    20341 gaacattcga tcattttatc agaacaacac cgcccgatga aaatcacaaa ggaaacattt
    20401 gctagactgc ttcggattac tgaagtcttg cctcattact ttgttggttc gaatgctgac
    20461 ttaccaattg ttggaggatc gattctttct catgatcatt atcaggcagg acgtcatgaa
    20521 tttcctatgg caaaagcacc gatagaaaaa cttatcaaac tagaagatta tccgcaagtc
    20581 atcgcaggag tcgtgaaatg gccgatgtct gtgatccgtt tgcaatcaac agagaaaaac
    20641 ttgcttattg aagcagctaa ctcagtattg gaaaaatgga aagcatattc ggatgaaaca
    20701 gtatctatca gagctttttc agcagatggt acaccacacc atacgattac gccaattgca
    20761 cgaagaaggg acaattactt tgagttggac cttgtccttc gagacaacaa tgtttcagaa
    20821 gaacatcctg atgggatttt tcatccacat aaagatgtcc aacatatcaa aaaggagaac
    20881 attgggttga tcgaagtaat ggggcttgct gttttaccac ctcgtttgaa accagaacta
    20941 gtagaagtag agcatttctt attaggagaa gaaaaccaga tggctgaata tcatcgtccg
    21001 tgggcagaac aattaaaaaa agaacatcct gatttgacga aagatacggt caccgatgtc
    21061 gtacaaaaat ctgtaggtca ggtttttgca cgtgtactgg aagacgctgg agtattcaag
    21121 cgagatgaaa aaggacaggc agcgtttgaa cgatttactg cgattttata aacgtaaaaa
    21181 aggaggagag acaaatggca acaattaaag acattgcgca gttggcagga gtttctcctg
    21241 ctactgtttc aagagttctc aactatgatc ctgatctttc cgttggctta gccacaaagc
    21301 aaaaaatttt tgaagcagca gaacgcttaa attatacgaa acatcgtaaa aatgcagcaa
    21361 atactaagca aacgcttcgc ctgatccagt ggtacgacga tacggaagag cttgaagatc
    21421 tttattattt atctattcgc ctaggaatcg aaaaaaaggc agaagaagca aacgttactt
    21481 tattgaaaga aacgtgggat tccattagtg atcttccggc agatggaacg atcgcactag
    21541 gaaaattcga cgaagctcag ttattagaaa tgaaaggatc ccaaaatgcc ttgcttttgg
    21601 tagattctga cggcacttct caaggaatcg actctctagt tgtcgacttt aagtcaagtg
    21661 ttcaaaaagt cattgaacac tttgtctccc ataaagcgca acatatcgct atgcttgctg
    21721 gaacagaata tacgaagaaa aaccatcagc ggctaaaaga tcccagaatt atggcatttc
    21781 aacaagtttt ggcagaaaaa ggctacgacg aaggtccaat tatcgaagca gatttttctg
    21841 tcgagtcagg atatcaagca gtgaagcagt atttaaaaac gaatccgcat gttcctgatg
    21901 cgctttttgc agctaatgat gcattagcga ttggcgcact gaaagcgatt caagaaaaag
    21961 gtttagtggt accagaagat atttctgtga tgggcttcaa tgatgtcagt gtagcgaaat
    22021 atgtaacgcc ctcgctttct actgtaaaag tttataccga atggatggga gagctagcag
    22081 tggagacgat tcttcaatta agtaattcca aagcaccggt ttcaagaaag attattgtgg
    22141 aaacagagtt gattattcga gaatcaacga aataaaagat ggaaaagctg tgggaaaatg
    22201 gagtgatacc gcagcttttt
//
LOCUS       DASHWW010000041        22132 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.041, whole genome shotgun sequence.
ACCESSION   DASHWW010000041 DASHWW010000000
VERSION     DASHWW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.041"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..523
                     /locus_tag="U2R64_001756"
     CDS             <1..523
                     /locus_tag="U2R64_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEM8918576.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            523..2109
                     /locus_tag="U2R64_001757"
     CDS             523..2109
                     /locus_tag="U2R64_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918577.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2128..2349
                     /locus_tag="U2R64_001758"
     CDS             2128..2349
                     /locus_tag="U2R64_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEM8918578.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2346..3107
                     /locus_tag="U2R64_001759"
     CDS             2346..3107
                     /locus_tag="U2R64_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEM8918579.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3487..3996
                     /locus_tag="U2R64_001760"
     CDS             3487..3996
                     /locus_tag="U2R64_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEM8918580.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4071..4610)
                     /locus_tag="U2R64_001761"
     CDS             complement(4071..4610)
                     /locus_tag="U2R64_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEM8918581.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="U2R64_001762"
     CDS             complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="U2R64_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEM8918582.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5623..6474
                     /locus_tag="U2R64_001763"
     CDS             5623..6474
                     /locus_tag="U2R64_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEM8918583.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            6502..7137
                     /locus_tag="U2R64_001764"
     CDS             6502..7137
                     /locus_tag="U2R64_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEM8918584.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7157..7930
                     /locus_tag="U2R64_001765"
     CDS             7157..7930
                     /locus_tag="U2R64_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8918585.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8338..9135
                     /locus_tag="U2R64_001766"
     CDS             8338..9135
                     /locus_tag="U2R64_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HEM8918586.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9113..9526
                     /locus_tag="U2R64_001767"
     CDS             9113..9526
                     /locus_tag="U2R64_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEM8918587.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9510..12155
                     /gene="mutS"
                     /locus_tag="U2R64_001768"
     CDS             9510..12155
                     /gene="mutS"
                     /locus_tag="U2R64_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEM8918588.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12173..14281
                     /gene="mutL"
                     /locus_tag="U2R64_001769"
     CDS             12173..14281
                     /gene="mutL"
                     /locus_tag="U2R64_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEM8918589.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14303..14863
                     /gene="maf"
                     /locus_tag="U2R64_001770"
     CDS             14303..14863
                     /gene="maf"
                     /locus_tag="U2R64_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HEM8918590.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14948..16936)
                     /gene="treP"
                     /locus_tag="U2R64_001771"
     CDS             complement(14948..16936)
                     /gene="treP"
                     /locus_tag="U2R64_001771"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEM8918591.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17159..17872
                     /gene="treR"
                     /locus_tag="U2R64_001772"
     CDS             17159..17872
                     /gene="treR"
                     /locus_tag="U2R64_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEM8918592.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17949..18395
                     /gene="msrB"
                     /locus_tag="U2R64_001773"
     CDS             17949..18395
                     /gene="msrB"
                     /locus_tag="U2R64_001773"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEM8918593.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18565..19167
                     /gene="ruvA"
                     /locus_tag="U2R64_001774"
     CDS             18565..19167
                     /gene="ruvA"
                     /locus_tag="U2R64_001774"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEM8918594.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19180..20181
                     /gene="ruvB"
                     /locus_tag="U2R64_001775"
     CDS             19180..20181
                     /gene="ruvB"
                     /locus_tag="U2R64_001775"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEM8918595.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20210..20788
                     /locus_tag="U2R64_001776"
     CDS             20210..20788
                     /locus_tag="U2R64_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8918596.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20840..21322
                     /locus_tag="U2R64_001777"
     CDS             20840..21322
                     /locus_tag="U2R64_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEM8918597.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21439..21813
                     /locus_tag="U2R64_001778"
     CDS             21439..21813
                     /locus_tag="U2R64_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918598.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7237 a         3991 c         4790 g         6114 t
ORIGIN      
        1 cgggggcaat tttttgacta tgctgattac tcctgcgaca gtggcacttg ccatccctct
       61 ttataaaaac ttccgtttac tgaaagagaa tttttatcct gtaatggctg cgattttagc
      121 aggaatagtc gcaaattgct tggttagtgt agggttcggt tacttcttct ctcttcataa
      181 agagatggtg atctcattac tacctaaatc tgtaacgacg gctatttctg tcgatttatc
      241 tcatacgatg ggcggggtga atgccgtgac acttgctatt gttgtctcta caggtatttt
      301 tggttcgctg atcgccactc atattttccg cctattcaag atcgaaagtc cagttgctcg
      361 cggtgtggcg ttaggaagta cttctcatgc tattggtaca gcaaaagcaa tcgagattgg
      421 tgaaatagaa ggaatcattt ccggacttgc gatatgcgtc aacggaatat tgaccgtttt
      481 attgctaccg ttattctttc agccttttgc tggcttgttt tgatgcgaaa accactattt
      541 tatgctacaa taaccaaaac gttcgagcat aaaaaaggag ggaaagacgt gtatttgtct
      601 tccgagtatc ttaaacaatt tgataaagat ctatattata agattctcct cctagaaagt
      661 tttgaggatc aagcttggca taccgctgca caattagcgc aagttgttca gctggatgcc
      721 cgcagcgtgt cgaaatacct gaacgagctg tctaaaaact atcagcagtt tagcggtaag
      781 acacaccctt tgtttacaaa aaatcaccgt tctggttata acttttatga tacgctcgat
      841 tcaattgaac atgagcgttt tttgatctat ctcgtgcaaa gtacgctgaa attccagttg
      901 ctgcacgaca ttttttttga agaattccat acaatgtacc aatttgcgca aaagcattac
      961 attagtgaat ctactgctca tcgaaaaatc aatgaatgga aacagcaact gcaaacttac
     1021 ggaattcggc tgcaacgagg tacatatatc gctcaaggcg aagaagaaat cattcgactt
     1081 tacttgcata tgacattctg gcagttgttt cgagggaaaa tctggccatt tgaaacgatt
     1141 tctcaaatgg acgtaaagaa tatggcagaa catatcatgg ctttttttaa tgttcgtctg
     1201 aacgagatca aaaaaagacg attggaatat atgctaggtg cctttttttt aagaaaatca
     1261 cagaagcatt atgttgtatt gaatgagaaa aaaagacggc tgatttctga caatctgttg
     1321 ttccagcgat tttgccaggt catggagccg gtatttccta attattttca agtagaagac
     1381 gagttaggcg cattatttct tgtactgatg actcgtgaag aatattatag tgatcctaag
     1441 atacggaaga aaatttttga ttttcatcaa caagcaaaaa caccgccctt tacagccctt
     1501 tcagaagcaa aagccgctct ttctctttat caggaagagc aggggctgcc agcagaaaat
     1561 ctaaccttcg aggcagaaaa ctatttattc agcagtcatt ttttcgccta tctttttcct
     1621 aatgcgaaag aaacgattga tggcaatagt agtgatttta ttaatcattt agttattgaa
     1681 aacaaggaat tgaaacaatg gctcgtacat ttttttgaaa gtagacacaa acatcccaat
     1741 catctggcat ttaaaaatca tgcgtttttg atggggcggt atctgactgt gtttaaaaca
     1801 ttaggagcct ttactccaca gcttccaaag atcacgatcc ttttaatgac agatttccca
     1861 ttatttgaag agcaactgtt agaggaggga ttacggacat ttttccgtaa tgagtatcag
     1921 ctgatttttc tgccaacaga ttatcggggg agagaagttg atcttctgat ttcgacaagt
     1981 aaagtccacc gcaaaccatg ggcggatctt gactatttta ttgtgactga agaactaaaa
     2041 ttaattgatt acatccaact atctcaaaaa tttgaaatga ttcaaaaaca aaaactatta
     2101 aaacaataac aaagaaggag aaaaaagatg acatttgaag aaattttacc agaattgaaa
     2161 aaaggtgcaa agattattcg taaaggatgg agtggatttg aactttatgt tgttctcgta
     2221 tccgatgatg aatttgatgg ctgtccggtg acgccgtact tattgatcaa aacaagtgac
     2281 gaaggttttt ccagcttcgc tcctacagtt tgtgatattt tagcagatga ttgggcgatc
     2341 gtagaatgaa aaaccagtat ccagatctag ctaaacaggt tgtatttatc acaggagctg
     2401 cttctggaat tggtgctgcg caagcccgag cgtttcttga acaagatgct tttgtatttg
     2461 gattagatca aaagttcggt aaaatggaag aaatttcttt gcgatttcct gaaacttttg
     2521 cctacgcact aggtgatgtt cgacaaatga aagaactcca acaagcggta tcgaaatgcc
     2581 aaaatcattt tggtgaagtt acgattttac tgaatacagc ggggatattg gatgcctaca
     2641 aacccttgat ggaaactgac gaatcgctgt gggatctgat ttatgagacg aatgtgaaaa
     2701 gcatgtatca gctgacaaaa atcatccttc ctgatatgat ccgccaaaaa agcggaacga
     2761 tcatcaatat ggcttcgatt gctggcttga ttgctggtgg aggtgggatc gcttatacaa
     2821 gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc tctggattac gcaggacagg
     2881 gtatccgagt aaaaggaatt gctccaggag ccatccaaac accaatgaat gcggctgatt
     2941 ttgaagggaa aggtgagatg gcagagtggg tggcaaatga aacaccagtc aagcgatggg
     3001 cacagccgga agaagtagct gagctgacgt tatttcttgc ctctcctcaa gcaagctaca
     3061 tacaaggaac gatcatccca atcgacggcg gatggttgtt aaaataacct tgtgtttttt
     3121 tcaagcttct gtatgataaa actaaagaga gaaacaacgg ttgatgataa aaaaagtcga
     3181 tgactgttcc cgacattcga tgccgaacag ccagttcaaa aaattctttt taataatcgt
     3241 taatattcga aactaagcgg cttttcacga cctcttgata taaacgatat tcaaaagctt
     3301 gcaactgcgg taacaagtcc agccaaatga aaaatataag gagctatttt tatttgacca
     3361 ttcttattac ttgttgcagg gcagcttttt cactaccttc tgcgacactt cagttggaat
     3421 tttcttccca tcctttggtc gcggtcatta ccaagataaa attatcttgc aaaggagaaa
     3481 tagaacatgg aaaaaaataa tacccgttca gccaaacgct ggacaacgac agatgtgact
     3541 cggatggcgc tagtcactgg tttatatgtg gcagtgacgc tggttttgtc tgtctttagc
     3601 tttggagtga ttcagattcg tctctcggag atgttcaact atctgtcctt gtataacaaa
     3661 agatacatcg tcgcggtaac agcgggagta gctttggcta atattgcttc tcctcttgga
     3721 ctgatagatg ttgcagtagg aagcgtcagc acgctgcttg tattgcttat caactataaa
     3781 atcactagtc gcatcaaaaa catgaaaatc aaaatggccg tgacagcatg cgtatttgct
     3841 ttttccatgt ttacagtagc tggtcagcta acgattttat atcaactacc ttttttcttg
     3901 aattggtggg tgattgcttt aggagaattg gcatcaatga ttgtcggtgg gataattatt
     3961 tattggatcg gtaaaaaagt ggatttgtca aaataaagat ctgtttaatt taaaataggg
     4021 cagcatggaa gagactgaat gttgagtctt cttccatgct gcttttttga ttaatttgta
     4081 tgaagaaatc gatttagccg ttttttcatc aagataccga tataagctgc tccagttgcc
     4141 ttgattgctt ccggcagtaa aaacggcagt agtccactgg caaatgcagt tgtaaaagta
     4201 agatcaccac ttattttcag ccagatcgtt ccgcagatca atgcagcaag agagcccatt
     4261 agattggcaa agattgcata taagtaatga gcatccgttc tttcgatcat ccaaccagtt
     4321 atccacgttt gtaagagaaa tccaatcaaa tatccgccag ttggcccaaa taaaacagct
     4381 atacctccag tcatccctga aaatacagga agaccaatca agccaagtaa aagataaact
     4441 ccaacagata tcaatcctag ttttcttccg agaaaagttg ctgttaatcc aatagcaaat
     4501 gtttgccctg tcaaaggaac caaaccaaaa ggaatggtca tctgagaaag gacagaaata
     4561 atcgcggcaa attccgcagc aagtatcaat tctttcaatg ttcggttcat aacgccctct
     4621 tttcgttaac ttaatatttt tatttggtta acgaaattgt aaaacaaagt gattactttg
     4681 taaatagaaa atataaaaaa agaccagcta tccaatagat agcggtcttt ttcaagaaag
     4741 cttttgaaat tataagcttt ggttgtagta ttcaacgaca agagcttcgt cgatttctgg
     4801 atatagttcg tcacgttctg gtaaacgagt caatgaacct tccaattttt cagcgtcaaa
     4861 gcttacgaat gctgggcgtc caacagttgc ttctacagct tcttttactg ttacgatgtt
     4921 ttgtgatttt tcacgaactg agatcacttg acccacttct acgtggtatg aagggatatc
     4981 aacgcgtttg ccatcaacta aaatgtgacc atggttaact aattgacgtg cttgacgacg
     5041 agtcgttgca agtcctaaac ggtaaacaac attgtctaaa cgttgttcta gtaagatcat
     5101 gaagttaaca ccatgtttac cttctttgat tttgctagct tttacgaaca agttacggaa
     5161 ttgacgttcg ttcattccgt acatgtgacg aagtttttgt ttttcagtta attgcatgcc
     5221 gtattctgat tgtttgccac ggctattagg tccatgttga cctggtgcgt aagggcgacg
     5281 tgctaattct tttcctgtgc ctgacaatga gatgcctaag cgacgagaaa ttttccatga
     5341 tggtcctgta taacgagaca ttaaaatttc ctccaatgaa tataagtttt tggagtaaaa
     5401 taatccgttg aaaaattcat aatcatatag tttgttcttc aatcttcacc tttgcagccg
     5461 cggttacaca atcgaacccg agacggggca acaaactagg gatgagttat tatttttctg
     5521 ctgcattatt ttacacaaat tacagtatat gatagatcat ccacgaatgt caagataatt
     5581 agtacataaa aacgctttac aaacctaggc tgtctttata aaatgagagg gtatgtgcaa
     5641 atggaaaaaa gcgaaggaag tttaaggaga aaatcaatga atccggtatc accattattt
     5701 gagaaaatcg atgcttcaat tgaaaagaag gcgaatcttt ttgaaaacag cttttcacgt
     5761 tacgctgttc gagcggttct cgcctgtttg tttttgactt taggaacggc tgtggcattt
     5821 gcgatcgcga tgaaggggga agatatcgcg catggtctag gaaagatttt atacgcattt
     5881 atgttcagct ggggtctggt catgattcta tacatgaacg ccgaattagg aacatcgaat
     5941 atgctttata tgaccgtggg tgtttttcgg cagagacttg ctttaagtaa ggcagccaag
     6001 attctatttg cctgtatttt tttcaatatg attggcggta tattatgtgg atttctaatt
     6061 tctatgacta cgccatttca agatttaacg ttggacaact ttatgttaga atcaatagca
     6121 gtaaaactag caaaaccttc agcaacgatt ttggtggaag ggatgtttgc gaatatcgtt
     6181 gtcaataccg ctgtactgat cagcatgcgg atgaaagagg atgtcggaaa agtgatcaca
     6241 gtcgtattca tcattttcat ttttgctttt ttaggatatg aacacgtgat agcgaatttt
     6301 cctgccttta cgcttactta ctttgcttct cacggacaga tggatggaat gacagtcagc
     6361 aatgtgttac ataatttgtt ttttgctttg gcaggaaatt atattggtgg cggtttagta
     6421 atgggactgg gatatgcttg gctgaatcag tcaaaatcat cctatgtgga ctaaaaagtc
     6481 gttcattaaa ggggaagtgc catggaagtt ttagtttttc caaaaaatga ggaaaaagcg
     6541 ttacaaatgg aaaagtacat gaaaaatctt ttttcctttg ctggagtacc taagccggaa
     6601 cgcgctcttt tacaacaacc gttactggat gagagcaaaa atttatctat ttctgaagtt
     6661 ttagcttttg ttcattatta ttatgaacaa atcgaaagag agtatcagta tgtagcgatc
     6721 gatttagtcc agaaaaacat caaacggctt acatttgaag acttagtcgt attgttgcca
     6781 ctagttcaga aaaaagaatg gtgggacagc atcgactctt ggagaaaagt atacagcaca
     6841 tggtgtaaag cctacccaga gcagcgtgaa gaagtctttc aattgtttga aaaaaaggaa
     6901 gatttttggc tacgtcgaat agcaatcacg ttgcaattag gttataaaca gcaaacagac
     6961 acaggactat tgatccgagc aatagacgaa gatcgtcaaa caaaggaatt ctttatccaa
     7021 aaagcaattg gttgggcatt acgcgattat agtaagaccg atgccgattg ggtaaaaaga
     7081 cagctgacaa cagatttgag taagttagct gttcgagagg caagtaagta tttataagaa
     7141 agcgagacga caagagatga gacgcaaatt atttgctttt gatattgatg gaacgttgtt
     7201 agattcaaac aaacaagctt tagatagcac aagagaagca ttggaaaaat tacgcaaagc
     7261 cggtcatctg gtcacgattg ctacagggcg gagccgattt catgcgcaag agatcattcg
     7321 cgatcttgat tttacgaact acattttatg taatggagcg gccggttttt tagaccatga
     7381 acaagtatat aagaatttac tagatcgcga ccagttggat gcgttcgttc aagaagcgca
     7441 tcatgagcag atcgatacag cttttgtcag cttagacaat atcaagcgtt cttcttccaa
     7501 tgatgtaacg gtgatggaag aagcgatgca ttctttcggt gctgtcttgc ctgaattaga
     7561 tcagtttttt gcagaggaac aagaaatata ccaagcgtta gcatttttcg atcaaacata
     7621 tgatgggaag ttctcttcat atgataaaat tcgatttgtc cgctggcatg agaacagtgt
     7681 agatgtcgta cctaaaaatg gttctaaagc agcgacaatt ctgcacttag cagaacaagt
     7741 aggcatccct catgaagaca tcatcagctt tggcgatgga caaaacgacc gtgaaatgtt
     7801 gcgcatgtca ggaattggga tagctatggg gaatgctgtg ccagaagtac aagcagaagc
     7861 taagatggtc actgatacaa acgatcagga tggaatttgg aaggcattga aagagttaag
     7921 cgtgatttaa aagaggttgt gaaaaagctg ttctgcatca agtaataagc ccagccaaac
     7981 aaaaatagct cctcctattt ttcgtttttc tgggcttatt accgcagatg caagctttcg
     8041 aacaccgttt aaggaagagg tcgtgacaga agtggtcagt ttcaagaaat aagaagggat
     8101 ttacgaaaat tgcttctcaa atttttgtaa aattacggct tatttctgaa gaagtagatg
     8161 aaacaacgtt tattcgggaa atgggactgt gacaagatgt ttgtcatagt cccatttttt
     8221 tattttattt ttcaaaacta agaaatacca ggaaagagtt ccttttgttt gaccttttct
     8281 ttcttattga aaacaactat aatatagagt gatgttaaaa gagaagagga atttagtgtg
     8341 cgggtattgt ttattggtga tgtagtaggt tcaatgggac gagagatgat tactgaatat
     8401 cttcctagat tgaagaagaa gtaccgtccg caagtaacga ttgtaaatgg tgagaatgcc
     8461 gcttctggac gtggaatcac agaaaaaatc tataaaaaat ttttgcaaga cggcgtagat
     8521 gtcgtgacga tggggaatca tacgtgggac aaccgcggaa tctttgagtt tgtaaatgaa
     8581 gctaaaaaga tggttcgtcc ggcaaatttt ccggaaggga cgcctggaca agggatggtc
     8641 tttgtcaaag tgaaccaagt cgaactggca gtgatcaaca tgcaggctcg ttcttttatg
     8701 gtggacttgg atgatccttt tcgtaaaatg aatgagctgg tagaagaagc cagaaaacgt
     8761 acgccgatca tttttgtaga ttttcatgga gaaacaacaa gtgaaaaaca agcaatgggc
     8821 tggtttttag atgggaaagt ttcagcagtg gtcggtacac atacacacgt tcagacaaat
     8881 gatgcgcgaa ttttgccaag aggaacagcg tatctgacag acgttgggat gacaggtccc
     8941 tatgatggta ttttgggtat gcgcagagaa cctgtaatcg aaaagtttct gactgcatta
     9001 ccaaaacgtt ttgaagttgt ggaacaaggc cgatcgattt taagcggctg tatcttggaa
     9061 ttggatgata cgacaggtca tgcaaaagaa atccagctga ttcagatcaa cgatgatcga
     9121 ccgttcatgg agtagaaaga gaggcagttt tttgcagcag gagccggaaa ttcaaaaaga
     9181 agtaaggaaa ctgacaaaac ttttaagaga gaatgaaacg atcattcgct acaaagaact
     9241 tgaagaaaag atccagcaaa accagtattt agctgagttg agagaaaaaa tcaaacaagc
     9301 gcaaaaagat gctgttcatt ttgcccacta tgacaaacca gcagcagaaa aagaagcaat
     9361 caaacaagcg gatcaattca tgcaagaatt tgatcagcat ccgcttgttg tagcttatag
     9421 aaaacagctg ttggaagcag atgatctgct tcatcattta acaactatga tacaagaaga
     9481 aatcaatgga caaatagagg aggaaaaaca tgcctcaaaa aactaaaaat actcctatga
     9541 tggaacaata tctaagcatc aaggcccaat accaagatgc ttttttgttc tatcgtttag
     9601 gagactttta tgaactattt tacgaagatg cgatcaaagc gtcacagctt ttggaattaa
     9661 cgttgacgag cagaaatcga aatgcagaag aacctattcc tatgtgcggt gtacctcacc
     9721 atgcagcaca aggatatatc gatgccttga ttgaaaaagg ctataaagta gcgatttgcg
     9781 agcaggtaga agatccaaag acgactaaag ggatggtcaa gcgcgaagtg atccagctag
     9841 tcactcctgg tacagtcatg gacagcaaag gattgtcggc aaaagacaac aattttttaa
     9901 cagctgtagt tagtcaagga aatgaatttg gctttgctta tgccgattta agtacgggag
     9961 aattgaagac ggctcggttg catgatgaag aagctgtttt aaatgaagcc tctgcattgc
    10021 agacaaaaga actcgtatta ggcagtgaga tcactgatac ccttcgtgaa cagctaagcg
    10081 ggcgtttagg gctagtcttt tctcaacaaa atgagatgga agaaaacgcg gaatttagct
    10141 ttttgacaag cgaactagtc gatccgctgg aaaaagaagc aaccggcaaa ctattgactt
    10201 atttatcggt gacacaaaag cggagtttag ctcatatcca aaaagcagta gaataccaac
    10261 cagatcattt tttgaaaatg gattattatt caaaattcaa cctagaatta agccaatcta
    10321 ttcggactgg gaaaaagcac ggcactcttc tatggttgtt agatgaaaca aaaacagcaa
    10381 tgggtggccg tttactaaaa caatggctag accgtccgct tatccaggca aaacaaatta
    10441 aagcaagaca agaaatggtc gcttctttgc tagacagcta ttttgaacgt atcgatttgc
    10501 agtcagcatt aacgaaagtc tatgatctgg aacgcctagc aggtcgagta gctttcggta
    10561 atgtcaatgg gcgagacttg atccagctga aaacttcttt agaacaagtg ccaatgatca
    10621 gagggttgat tgaaggaatc gatcaaggtc aatggcaaag tctgctttca gaaatgcagc
    10681 cgatggacca tctcgtccaa ttgatcgacc aagctatcca agatgatccg ccgttacaaa
    10741 taacggaagg aaacatcatc aaagatggat tcaatgagca gctcgatatg taccgttctg
    10801 ctatgagaaa cggaaagaaa tggttggcag aacttgaagc aaaagagcgt caagaaacag
    10861 gaatcaagaa cttaaaaatc ggatttaacc gcgttttcgg ttattatata gaaattacaa
    10921 aagcaaatct tggaaatgca gaactggaga agtatgaacg aaaacaaact ttagcaaatg
    10981 cagagcgttt catcacacca gaactaaaag aattggagac acaaatcctc gaagcagaag
    11041 aaaaatctgt tgatttagaa tatcagttgt ttttagctgt gagagaagaa gtcaaaaagg
    11101 ctatccagcc gctacaagta cttgcaaaag caatcagtgc agtagatgtg ctacaaagtt
    11161 ttgcaacgat cagcgaacgc tatcagtatg ttcggccaga acttgtcagt gacaagcatc
    11221 agcttctgat caaagacgga cgacatcctg tagtagaaaa agtattagga catcaggaat
    11281 atatccctaa cagcgtagaa atggcagaag acgaaatgat cttgctgatt acaggaccga
    11341 atatgtctgg taaaagtacg tatatgcgac agttggcatt aactgttctg atggcgcaaa
    11401 tgggctgttt cgttccggca aaacaagcag ttttacctat ttttgatcgg atttttaccc
    11461 gaattggtgc aagtgacgac ttaattgctg gacaaagtac ttttatggta gagatgatgg
    11521 aagccaatca agccctgcgt tatgctacgc caaacagttt gattttgttt gacgaactag
    11581 ggcgaggaac agcaacctat gacggaatgg cgttggccca agcaatcatc gaatatatcc
    11641 atcgtcatgt acaagcaaaa acactctttt ctactcatta tcatgaactg acggtacttg
    11701 agaaagaact tccgcagctt aaaaatgtcc atgttggagc cgttgaaaaa gacggagaag
    11761 ttgtcttctt gcataaaatg atggatggac ctgcggataa aagctacggc atacatgtgg
    11821 caaagatcgc aggattgcct tccaatctac tagaacgagc agcagatatc ctgcatacgc
    11881 tagaaaatgg cgataacgga caccatactg ttccagctga agtagaagag aaaactaaaa
    11941 cagccaaaca ggagcaaata aaaccacctg cagaaaaagt aaatcaagac catatacaag
    12001 accgtgtaaa agaagaaaac caacagcttt ctttattcag tgaattatcc gaaaatgaaa
    12061 cagaagtcat tgaatcactg aagcaaataa atttactaga aatgacgcca atggatgcac
    12121 taaacacatt atatgaatta caaaaacaac tgtaggaaga aggcggatat cgatggccaa
    12181 aatccaagaa ttatctgaac gtttagctaa tcagatcgct gcgggagaag tagtggagcg
    12241 accagcttcc gttgtgaaag aattagtgga aaatgcaatt gacgccggca gtactcagat
    12301 tgatatctta gttgaagaag cgggactgcg gacgatccaa gtgattgata acggagaagg
    12361 cattttggca gacgacgtag agaatgcctt caagcggcat gcgacaagta agatccataa
    12421 tcgcgacgat ctttttcgca tacgaacgct gggctttcga ggggaagctt tgccaagtat
    12481 tgcctctgtt tctgaaatga ctctggaaac ggcgaatcag gaagaaaaac aaggcaccta
    12541 tctgtcgctg aaaggcggag aagttattga gcatcgacca gcaccactgc gtcaaggaac
    12601 gaagattacc gtcagcaatc tgtttttcaa tacgccagcc cgcttgaaat acgtgaaaac
    12661 actgcacaca gaattagcga acatcgggga catcgtcaat cgactggcat tgagtcatcc
    12721 atcgattgct tttcgtttag tacatgatgg aaacaaaatg ctggcaactg ctggaaatgg
    12781 cgatctgaaa caaacaattg cgggaatcta cggattatct accgcaaaaa aaatgctgaa
    12841 aatcgaagga aaagatctag attttgagtt atttggctat gtttcattgc ctgaggtgac
    12901 tcgtgccagt aggaattact tatcgacgat catcaatgga cgttttatca agaacttttc
    12961 cttgaataaa gcaatcgttg caggttatgg gtcaaaatta atggtcggtc gtttccctat
    13021 tgctgtattg gaaatcaaaa tggacccgct tttagtagat gtaaatgttc atccgacgaa
    13081 gcaggaagtc cggctgtcga aggaaaaaga actaacagag ctaattagta acgccattca
    13141 aaaagcattg tctcaagaaa atctgattcc aagtgcagcg gataatctac ggtttaagaa
    13201 aaaagtacct gatcagccta aaacagaaca aatcgaaatc gatttgtcct acgcttttga
    13261 agaagaaaaa cctaaaaagc caagtagttt gaattttgat cgagagacag gtaccttttt
    13321 cgtagaagaa ctaaagaaca catttgttga cagaattgtt gataagtctg tggaaaatgt
    13381 tgaaaactat tctggttttt ctgaagaaaa caccacttat ccagaaaaaa cagcgaaaac
    13441 ggtggataag tttggtgaaa atgttgataa ctttgtagaa aaaacagtgg aaaaatctga
    13501 aaagaaagaa tttcccattg tggataacat ggagaaaaca aatgaagaac aagcagataa
    13561 atccgtagaa gaggatgaaa agatttacga ggaagaattg acactccatc ctgaatttga
    13621 tttcactcaa ggaaacgaca aaacattaga acaagccatc aagaaattag aaacggaaaa
    13681 accagtacaa cgttttcctc agttggaata ttttggacag atgcacggaa cgtatctttt
    13741 tgcccaaagt agcgatgggt tgtacatcat tgatcagcat gctgcccaag agcgcattaa
    13801 gtatgaatat ttccgggaaa aaattgggga agtatctgat gatctgcaag aattgcttgt
    13861 tccatttgtg ttagactatc caaacagtga tgctttgaaa ttaaaagagc aaaaacactt
    13921 gctagaagat gcagggattt atttagaaga atttggtcaa aacagcttta ttgtacgggc
    13981 ccatcctact tggtatccca atggagaaga agaatcgatt attcgggaga tgatcgatat
    14041 gctgctgaca actggaagtg tgagtgtaaa aaaattccgt gaagcaacag caatcatgat
    14101 gagttgcaaa cgatcgatta aagccaacca ttatttgaat gaagcacaag cacgtgtgct
    14161 gctgaaggat ctggcacgat gcgaaaatcc tttcaattgt ccccatggcc gtccagtatt
    14221 gattcacttt accaattcgg atatggaaag gatgttcaaa cgaatccaag acccgcatta
    14281 agtcaaagag aagagggaaa acatgaagat tgtattagca tcccaatcac caagaagaaa
    14341 agagttattg gctcatatcg tttcagaatt cgagattgaa cctgctgata tcgatgaaac
    14401 gccatttcca gacgaacagc ccgtcgatta tgttcgtaga atggctgaag aaaaagcacg
    14461 aactgtctgg gaacaagatg aaaaagaaga ccatttagtg attgccagtg acacgactgt
    14521 tgttctcaat caagagatca tgggtaaacc agaagatctg gctgaggctg aattcatgct
    14581 gaaaaaacta agcggggaaa cacatactgt atatacagct gttgttttaa aaacaaagga
    14641 acgagaagaa cggatactag cagaagcaca tgtcactttt tatcctttga cagacgaaga
    14701 gatcaaacgc tacttggaga cgggggatta tgcggataag gcaggggcat acggcatcca
    14761 aaatgctgcg agtgtattcg tcaaagaaat ttctggagat tattacagta tcgtaggatt
    14821 tccgattggt gctgtcaatc aggcactgaa aacattcatt taaacaaaaa agcggactat
    14881 ctgattttcg attgaaaatc catgatagcc cgtttttttt attgaaaaga ttacttatct
    14941 actctgacta agattttact tcagctttac cgactgcttc gcccgggcga acaagtcctg
    15001 attggtcaag agaaagtcct gcaacttttt cattattggt caaagcaaca ataatgtcag
    15061 ttttcttgcc agcttgttct atttctggca aatccatttc agcaatcagg gtctctggtg
    15121 tgacaaggta tccttctttc acgaatacat tgaaaggaac accctttagt tcaacagtat
    15181 ctaatcccat gtgaacaagt acttccagcc cctcattaga aagaatacca atggcatgtt
    15241 ttgtttcaaa gacactcgtc actttaccgt ttactggtgc atagactttg ccgtttgacg
    15301 gttcgacagc ataaccgtca cccatcattt tttgtgagaa aactgggtca tttacttcag
    15361 ttatttcctt gatggtccct gcagcgactg cgaataatgt ttcttttgtt gcaactgccg
    15421 taccagttgc tgaaacaggt tcgaaagact gtggcgttgc tgttgcgcca tttgctgttt
    15481 gaagttgtac atcagcagca ttttcaggaa cagcaggatc aatcttattc aaaattccct
    15541 gacgtctaaa gatgatcgtc aagccaaatg gaatgatgac agcaatgatc attgcgatga
    15601 tgaaaggtac ccatgtttct gcttggatag ctagtattcc tggcaaaccg cctactccga
    15661 tcgcgttagc tcgaacaccc atcaagttag caaacatgcc agctaatcca gagccgacca
    15721 ttgcagcgac gaaaggatag acgtatttca aattgattcc gaacatagca ggttcagtta
    15781 cgcctaagta acaagaaatc attgctggaa tcgagatttg ttcttctttt ttattcccac
    15841 gatgtaagaa gatgatggct aagactgcag agccttgggc gatatttgat aaagcaatca
    15901 tcggccataa attcgttgat ccgaaatctg caatcagctg catatcgatg gcattggtca
    15961 tatggtggag accagtaatc actaaaggag catacaggaa tccgaatacg gcactaaaca
    16021 accagctgat agaagacgtc aatccagtat ttacgatatt tgagatccag cttccgactg
    16081 tccagccgat aggacctaaa ataacgtgtg cagctaaaac agttggtaac aatgaaaaca
    16141 atggaacaaa aatcatcgag atcgactgag ggatatattt gcggaagaag atttctagat
    16201 acgctaacat aaaccctgcc agcatggctg gaataacttg cgcttgataa ccaatcatct
    16261 ggacttgagc aaaaccaaaa tcccaaaatg gaatatctgc tgcggctgtg gaagctacac
    16321 tataagcatt taataattgc ggagaaacta acgtaattcc taaaacgatt cctaatattt
    16381 gtgtagtacc catctttttt gcaatactcc aagtgatacc tactggaaga aaatggaaaa
    16441 ttgcttcacc cggtaaccac aaaaaggcat tgacaccatt ccaaaacttc gagtgttcaa
    16501 cgattgttcc accaagactt tcaaactgga taccttcaag tacatttctg aatccaagga
    16561 tcaatccacc gacaatgatt gcaggaatca gtggtgtaaa gatttctgct aaaacggcaa
    16621 tagcacgttg aacgggatga aggttttgtt ttgcagctgc ttttccttgt tctttggaaa
    16681 ccccttcaac tccagatact gcaacgaagt cgttataaaa agtagaaaca tcgtttccta
    16741 tgatgacttg gaactgtcct gcattcgtga acatcccttt tacgctaggt atatcttcga
    16801 tcgctttttc gtccgctttt cctggatcat tcaggacaaa acgcatacga gtcgcacaat
    16861 gactaactgc agcaatattt tcttttccgc cgatatcatg taacagcttc tcggcatctg
    16921 cttgatattt tgccatatca ataaacccct ttctcttaac ttgtctatgc aagttgtttc
    16981 ttcatttact atactttttt tcggagagaa ttgcaagcgt tttattaaaa agtacgagag
    17041 aaaatgatat cgttttaaaa agcttaaaat aagcttttct taaaaatagg aacattgaaa
    17101 tacaaaaaga gctgtagtat agtgaagaaa tgatggaaga acgagtgagg gaaaaaacat
    17161 gaataagttc aatgaaattt ttttagattt ggaacagaaa attttagcga aagaatatcc
    17221 tccgcattcg cttttaccca gtgagaacca attgatcaaa atttatggtg tttcacgaga
    17281 aacaattaga aaagcgctga atcttttgac tacggaaggt tatattcaaa aaaaacaagg
    17341 aaaaggttcg atcgtactgg atcggaatcg cttcgacttt cctatttctg gattgactag
    17401 ctataaagag ctacaggaga cccaacgtat tccaagtgaa acgatcatcc atacgttaga
    17461 agaaacagaa gtgacaaaag cattgaacga gatcactggc tgggagatcg gtgcgcctgt
    17521 ttggcatttg atacgcgaaa gaaaaatcaa tggcgaagta gttatattag acaccgatta
    17581 tctattaaag gaaatcgttc ctattttaac tccagcacaa gcacaaggat cgatctatga
    17641 atattttgaa aatgagcttt ctttgacgat tgcttacgcg caaaaggaga tcacagtaga
    17701 agaagtaacg gaaatcatga aaacagcgat ggatcttcac gatgacactt atgcagtagt
    17761 agtcagaagc ctcgttcatc tggaagatac ccgctgtttc gagtattctg agtcggttca
    17821 ccgattagat aaattccgtt tcgttgagtt tgcccgacgc cgaaaagtgt aaatagttca
    17881 aaagaaagca aattgttggc atctgtccac tttggcgcta tgataggatc acaaaggggg
    17941 catttttaat ggataaacca ataagaccag aaaaagaaga actgaaagaa aagttatcac
    18001 ccatggctta tgcagtcaca caagaaaatg caacagaacg accatttagc gggaaatatg
    18061 atgattttta cgaaaagggg atctatgtag atatcgtcag cggtgaaccg ttattcagct
    18121 ctgcagaaaa atatgatgca ggttgtggct ggccatcatt cagcaaacca ataacgaaaa
    18181 gacaagtgcg cgaaaaagcc gatttttctc atggcatgca tcgaatagaa gttcgaagca
    18241 aagaagcaga ttctcatctc ggacatgtgt ttaccgatgg accagtagat caaggtggtc
    18301 tacgttactg catcaattct gcctcactga aattcattcc atatgaaaag atggatgaat
    18361 taggttatgg ggaattcaaa tcacttgtag aataatggaa atacacaaag agcggtacaa
    18421 tacggggatt tactcgatcg tccgctcttt ttttattcaa gcgattgcta tttgaaagaa
    18481 acgctcccta gactcctttt ttcacaaggt gaaatgtgct acaataaagg gaacgtatgt
    18541 gtgcaaaaga aagaggacta gaatatgtat gaatatctga caggtgtggt tacctttatc
    18601 aacccctatt acatagtagt agaaaccaat ggtatcggct accagatcgc actaggaaat
    18661 ccttaccgct acagtagcaa actaaatcaa aaaataaaaa tttatgtcca tcaggtaata
    18721 cgtgaagatg cgcatcttct gtatggattt gattcgctag aagaaaagca actgtttttg
    18781 cgattagtaa gtgtttcagg aatcggtccg aaaagtgccc ttgcaatcat ggcaagcgaa
    18841 gaccactccg gtttgattca agcagtagaa tccagtgatg tcacttattt gacgaaattt
    18901 ccaggagtag ggaaaaagac agcacaacaa atgatcttgg atctaaaagg aaaattcggt
    18961 gagctgagta tcgatacacc ttttagtcta tttgatgaag caaacacaaa agacgctaca
    19021 gctctatctg aagcaatgga agctctctcg gctcttggtt acagtgatcg agaaatcaaa
    19081 cgtgtagaaa aacaattaaa agaagtagat aatcagacaa cggatgagta tctacgccaa
    19141 gcactcaagc taatgatgaa aaaataagga ggagaccaaa tgacagatga atacttgtta
    19201 tcaccagaat ctggcgaaaa tgaactgagt ttggaaaaat ctcttcgacc acagctgctt
    19261 tctcaatata tcggacagag aaaagtcaaa caagaacttc agatttacat cgaagctgcc
    19321 agaaatcggg aagaaccttt agatcatgtt ctgttgtacg ggcctcctgg attaggaaaa
    19381 acgacgatgg ccatggtcat tgctaatgag atgaccgtaa atattcgtac gacgagtggc
    19441 cctgctatcg aacgtccggg tgacttagta gcaatcttga atgaactgga agcaggggat
    19501 gtcctgttta tcgatgagat ccatcgatta cctagagtgg tagaagagat gctttattca
    19561 gctatggaag atttctatgt agatatcatg gtaggacaag ggccaaccgc acatccggtt
    19621 catttccctc ttcctccctt tactttgatt ggcgcgacga cacgggcagg tatgctttct
    19681 gcacctttac gagatcgatt tggcatcatt tctcatatgg aatattatga cgaacaggat
    19741 ctgcaggaga tcgttttacg ttcttcggat atttttcaaa cagagatcat tgaagaaggg
    19801 gcattggaaa ttgctcgccg atcacgagga acgcctagaa tcgctaatcg cttgctcaaa
    19861 cgggttcgtg attttgcgca agtccaagga gacgggaaaa tcgatcgtcc tatagcggat
    19921 caggcactta ctttgctaca ggtcgatcag gctggattgg attatgttga ccagaaattg
    19981 ttgcgaacaa tgatcgagtt atatggcggc ggaccagtag ggttaagtac gctttcagta
    20041 aacataggag aagagcgtga gacggtagaa gatatgtatg aaccgtatct gatccaaaaa
    20101 ggatttttaa agcgtacacc tagagggcga attgctactg cttatgccta tgaacatttt
    20161 ggttacgact atcatatatg atttttgctt ttagattgga ggaaaatgaa tgagtgatac
    20221 aacacgtacg aaacaattga tcaaaaacgt attgattgat ttgtgccaaa cgcaatcttt
    20281 tcgaaaaatc agcgtccaaa aaatcgcaaa cgaagcaaaa atcaatcgac aaacatttta
    20341 ttatcatttt acagataaat acgatttgct tcgttgggtc tattgtgagg atgcattgca
    20401 ttatttagat ccacaatgtc tttcacttga taattgggaa gagcaagcat tgaaaatgct
    20461 gaaagcaatt gctgagaaga aagaatttta tgcaaatact gtgctttctg acccagaaat
    20521 tttacaaaaa gagttttctc aactgatcca aaaatcattt atcaagattt ttgaacaaat
    20581 ggatgaagaa agacaacttt ctgcaagaga caaactattt tatgctcgtt ttttttctta
    20641 cggttgcagt ggtgtattag tcaattggat cacgaatgaa tatgaagaaa caccgatgga
    20701 aatcgctatg cagcttttcc gtttagccaa ggatacggaa ttatattctt atcgtcttta
    20761 tgcaaaagaa gagttggaag aacagtaata gaaaaatttt ttgttggaaa agcaataatc
    20821 gctaaaagga gatggggaaa tgacaaaaat tttatttgtt tgtttgggaa atatttgccg
    20881 ttcaccgatg gcagaaggct tgctgagaaa acgaatagca ttagaaggaa gggaagcaga
    20941 attttttgtg gattctgctg ctacaagcac gtatgaagtt ggaaagacac cgcaccctgg
    21001 aacgaaaaaa atattaaacc aagaaaaagt agatatgacg aatatggttg ctcggcaaat
    21061 cacaccccac gattttgaaa cttttgattg gatcattggc atggatcaag aaaatgtaga
    21121 agaactgaaa cgaagagcac cacgctcagc gcaggggaaa atccatttgt ttttaagtag
    21181 cattcctgga aaagaaaaag aaaatgttcc cgacccatac tataccaata actttgatga
    21241 gacatatcac ttgatcacag aaggcctgaa tcattggtgg aatatttgga ttgatgaaaa
    21301 taaaataaca aacaatttgt aaagttaacg ctttcttttt aaggcgatgt tagagcattt
    21361 ccttgttttt ttgtaaaatg ttaggtaaaa taaaattaat taagtaacac tttcttagct
    21421 aaaggaggag tgcattcgat gaacgaagag acagtatcgc caatgaagaa gcttacgaag
    21481 ttagttactc atacttcgta tcaacttttt gattcttttg taaatgacac tgaagaacat
    21541 gctaagaatg tacgattgca aggaaagttt attcttgagc tgcaaaaagc tgctactgaa
    21601 catagtctag ttatcttaca agtaagagca aatcgtttga gtagcaagta tgaaacgatc
    21661 tcaggctggg tggcgacaaa aacggtcgaa aaagaccgag tgatgatccg cctacaaaac
    21721 gaagagcagc agatccggat ggttcctgta gaacaaattg aaaaaataac aatcctttca
    21781 ccagcagggg aacaggaacg gttatcaaaa taatttatac cagatagaaa agcacgtatg
    21841 agcttgtacc atcaatcatt actaatcaaa aataaccgaa tgctttaagc tgatatcagt
    21901 aaaacggaac gttttaggat gagtatcata gcatgacagc attcggttga ttagttgaat
    21961 cgattggatg gtacaagttt ttttgataaa aaaaggtcct gctagccggg gagctagcag
    22021 gataaggagt taaaaatgaa aaagtgttgt tagggttgtt tgttggtatg cttatataat
    22081 agtcattagt tgtgaatatt ttgtgacgaa agttttcgaa agttgttaag tt
//
LOCUS       DASHWW010000042        22079 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.042, whole genome shotgun sequence.
ACCESSION   DASHWW010000042 DASHWW010000000
VERSION     DASHWW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.042"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            95..1870
                     /locus_tag="U2R64_001779"
     CDS             95..1870
                     /locus_tag="U2R64_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HEM8918599.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(1936..3522)
                     /locus_tag="U2R64_001780"
     CDS             complement(1936..3522)
                     /locus_tag="U2R64_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HEM8918600.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            3773..3997
                     /locus_tag="U2R64_001781"
     CDS             3773..3997
                     /locus_tag="U2R64_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEM8918601.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            4139..5890
                     /locus_tag="U2R64_001782"
     CDS             4139..5890
                     /locus_tag="U2R64_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8918602.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            5890..7674
                     /locus_tag="U2R64_001783"
     CDS             5890..7674
                     /locus_tag="U2R64_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918603.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(8023..9363)
                     /locus_tag="U2R64_001784"
     CDS             complement(8023..9363)
                     /locus_tag="U2R64_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8918604.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            9542..10393
                     /locus_tag="U2R64_001785"
     CDS             9542..10393
                     /locus_tag="U2R64_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8918605.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            10447..12198
                     /locus_tag="U2R64_001786"
     CDS             10447..12198
                     /locus_tag="U2R64_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8918606.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            12202..12372
                     /locus_tag="U2R64_001787"
     CDS             12202..12372
                     /locus_tag="U2R64_001787"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8918607.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(12412..13314)
                     /locus_tag="U2R64_001788"
     CDS             complement(12412..13314)
                     /locus_tag="U2R64_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8918608.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            13545..14948
                     /locus_tag="U2R64_001789"
     CDS             13545..14948
                     /locus_tag="U2R64_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEM8918609.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            14948..16381
                     /locus_tag="U2R64_001790"
     CDS             14948..16381
                     /locus_tag="U2R64_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEM8918610.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            16526..17452
                     /gene="trxB"
                     /locus_tag="U2R64_001791"
     CDS             16526..17452
                     /gene="trxB"
                     /locus_tag="U2R64_001791"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEM8918611.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            17666..19393
                     /locus_tag="U2R64_001792"
     CDS             17666..19393
                     /locus_tag="U2R64_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEM8918612.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            19408..19758
                     /locus_tag="U2R64_001793"
     CDS             19408..19758
                     /locus_tag="U2R64_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEM8918613.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(19850..20710)
                     /locus_tag="U2R64_001794"
     CDS             complement(19850..20710)
                     /locus_tag="U2R64_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HEM8918614.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            20802..21230
                     /locus_tag="U2R64_001795"
     CDS             20802..21230
                     /locus_tag="U2R64_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEM8918615.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            21392..21568
                     /locus_tag="U2R64_001796"
     CDS             21392..21568
                     /locus_tag="U2R64_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEM8918616.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            21595..22041
                     /locus_tag="U2R64_001797"
     CDS             21595..22041
                     /locus_tag="U2R64_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HEM8918617.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7094 a         3873 c         4740 g         6372 t
ORIGIN      
        1 tttaaattta gacaaacaag gtatactggt agaaaagtaa aaaaacgaaa agtttcacaa
       61 gcaagtggca aaacgtgatt ggaaggacga aaagatgctg aacactttaa aacccttgat
      121 caaccaacta aaaaagaaac atacatactt tattcttggc atagccctat tatttacaat
      181 tattcgtttg tatttatata gtaaagcaat ctatggaaca gacatgtcgg caacctatga
      241 tgaccagctg ctgattcgct atgctcaaaa tattttggac ggtaaatggc taggggagta
      301 tacgactaca acactttcca aaggaatctc ctacagctta tttttagtac ttgcacataa
      361 actgcatctt tcttatgcag ttttgttcgg catgttcagt atttttgcca gtatattggt
      421 tgcactcgcg tttaaaccga ttgtgaagaa caagtatctt cttttaagta tctattttta
      481 ttttttgttt tctccgatta gttttacaca tgaatattcc actcgaacat atcgtaatgc
      541 cctcgtgatt ccggctgttg agatcattat cgcttgttta ttagctattt attaccgcaa
      601 atacggttct agcagaaaat tgctgccatg gtttttaggg ctttctgtcg cttttccttt
      661 cttttggttc attcgcgaag attctatctg gcttcttcct tttactgtag tagctttggg
      721 tatcagtttc gtccagatct tgctagggca agacttttct ttcaaagaag taaagaagtt
      781 aaaaaaacga ctctttcttc tctcgaaacg ggaatggctg aaactttcat tgtttttact
      841 tcctatagtt ggcttttcca tcgtctatca atggatcgaa tataaaaatg agacaacata
      901 cggtattgca accatcaatg accgttccag tggagaattt ggacgtttga tgaaacaact
      961 gatccgaata gatgatgaaa cgaacttgaa taaagaaaac agtgagatat gggtctcaca
     1021 tgctgcacta aataaagcat tagccgcatc tcctacattc catactgttt ctacccgtat
     1081 tgacgaatta tatacgactc acgcgtggac tcaaggtgga aaagtaaaag aattacccgg
     1141 agatatcatc ttttgggcat tgcgagatgt ggtaagcgaa tctggttatt accaaaacaa
     1201 tgcaaaagaa accaatgatt tttggaaaaa agtcaaccaa gaattagaag aagcctatca
     1261 caagggaaca atcaaaaaga aaaaagagtt ctatctgatg ggatcaggag atggaaagac
     1321 gatgagtgat ctgccaatcg tattcgattt ccttcaatca ggatacgctt atgcatggcg
     1381 atataaagat ttccatcaag gaggaaatta tagtttcgga acgcaagaac aagtcaaaca
     1441 ggctcaagaa ttattaaacc ttccgctaat ggagaattgg atcgatagta atgaaccgag
     1501 aacacctaat ttccaattaa caaaatcagc aaaagtcgcg aatgtcatca taaaaattta
     1561 ccaagttctg gctattcccg tgctgattgc ttcaatagca gggatattac ttatgatact
     1621 aggaaccgta tttgcaaaag ctgatcgtgc ctattatagt tcctctttga ttgtggtcac
     1681 cggattaata ctgacacaat tggtttttct tttcggtgtc tcatggtttt gttcttatgc
     1741 gccagaaaaa aaggactatt ttttaagtgt ctacactggt gcaggcgtgc cattaacgca
     1801 attcatcgta gtaacaagca tgctagtttt cagtaaatta aatctgaaaa aagctttatc
     1861 ttctaaataa aaagaccctt ggtagctaga tttttaacct aactatcaag ggtctttgtg
     1921 tggaaaaatc agtttttatt cgatttcttc taccgtttcc tgcaaaagct gttcatattt
     1981 tttgtttcct ttatataaat caccaatcgt ccatgccaac aggagaagga caagaacaat
     2041 gattacataa gcgatgtgat cagccaatgc tagttgagcg gaagtggctt gctcgccgaa
     2101 gaaactttcg atctgtcctg gtaatcctcg taagttcaag taagttagac taatcacaga
     2161 gaaccagcca agaagtttta cgatgaatga atttttaaat cggctaccca tctccgcttg
     2221 gctgttggtc atcatcagta aaggaatcat cgaaaacggc aacgcaaaag ccaagaacac
     2281 ctgggattca ttcattaagt tattcaaagc ggcatgttct tcgatcgttc cttttgtact
     2341 tgtaaacaaa acacaaatca atacaggaat cacagaaagc aatcgtgtga ccagtcttct
     2401 tagccaaatc gggatacgca tatggatgaa tccttccatg atgacttgac cggtcaacgt
     2461 accagtaata gtagagttct ggccagaagc aagaagtgct acagcaaata aagtggacaa
     2521 gataccagat tttgctacag caatcaaaat accattgctc atagctgatg gatcagataa
     2581 agcttcatac agaccaaaaa aggaaggatc ttggacagaa ccggttttga agacagcgac
     2641 acccatgatc aatagcagtg cattgactag aaaagccatt gacaactgga tattagaatc
     2701 ccaagtagaa aaacgtacag cttgtgctac atcttcttcg ttttggtgat cgatcttccg
     2761 agtttgtgaa actgctgaat gaagatataa gttatgcggc atgactgttg caccaataat
     2821 ccctaaagct ccagtcagcg gagtttcgcc gccgatgacc ggtgagtctg agaatgtatg
     2881 actgttaggg ataaagccag caaataaact gtgccaatct gggttagaca agccaacttg
     2941 atagacaaaa acgaataaaa tgacgaaaat taagcagaca accagtgctt cgatcttacg
     3001 aaacccgact tttgtcagta gtaagagaac gaaaacatct aatacagtaa taaagacggc
     3061 aatcaccaat ggaatatcaa aaagtaagta gagggcgatt gctgcaccaa tgacttctgc
     3121 aatatctgtt gccataatgg ctaattcagt caagatccat aaaatgacac ctaatgtctt
     3181 acttgtgcgt gctcggattg cctgtgccaa atccatttgg ctcacgattc ctaattttgc
     3241 tgccatatac tgtaaaagca tagcaatcag actagacatc aaaataactg acatcaataa
     3301 atattggaaa ttttgtcctc cggtgatcga agtagaccag ttacccgggt ccatataccc
     3361 aactgctact aacgcaccag gtccagagta agcaagaagt gttttaaaaa aacttttccc
     3421 ctttggtaca tcaactgttc catttacttc agctaaagat aaaccatttg tatgttcaat
     3481 aagtcgatgc ttatgaaatt gtttattgga ttgattattc aagaaaaaac cacctttcct
     3541 atttatctac gattacattc tacacctcaa aaagaaaaaa ttaaagaaaa agattcggta
     3601 cgcctaattt tttttcatgg cgcgtcttgc tagatgacga aagaaatttt gttctcctct
     3661 aaaaaaacca ctattttttg catgaaacta aagaatacgc ctttcttttt tcaataaact
     3721 ttagtaaaat aagtcattga gagcaattcg gaaatagaaa ggagagattt atatgttatc
     3781 aacaggtatt gtcgtactta ttgctattat tgctttgcta atcggcgcag taggtggctt
     3841 tttcctagcg cgtaaatata tgaaagacta tttagaaaaa aatcctcccg ttaatgagga
     3901 catgttgcga tcaatgatga tgtcaatggg gcaaaaacca tctgagaaga aaattcgcca
     3961 gatgatgcag caaatgaaga accaagggaa aaaataggtt ctgacccaac gactttttac
     4021 gggctgattt tttcagtccg ttttttattt cgtaatttgt tagactattc agattattca
     4081 gcaaaaaaga caagcacaga caatcctagg ctcttgataa agacaaagga ggagtaaaat
     4141 gtcgattttt agaaaattag gctggttttt tcgtcaggaa aagaaacatt atttaattgg
     4201 ggttttctcg ctattcgcag tggccttggt acagttagtt cctccaaaag tgattgggat
     4261 catcattgat gagatcgccg ataaaaattt atcaataaag atcattttcg ggtggatctt
     4321 cctattgatt atcgctgctt ttttacaata tctttttcgt tatatctggc ggacgaatat
     4381 ttggggaagt gcagctcgat tggagaaaga acttcggcag cagttattca aacattttac
     4441 agaaatggac aatctctttt accaaaaata tcggactggg gatttgatgg ctcacgcaac
     4501 gaatgatttg aatgcgatcc agaatgtagc aggagctggt atcttgacct ttgcagattc
     4561 agtgattacg ggcggaacaa cgatcattgc gatgattttg tttattgatt ggcgcttaac
     4621 actgattgcg ctgattcctc tgcctttgct ggccgtcact tcacgagtgc tggggtcaaa
     4681 actccatgat gcttttcgtg attcgcaaga agctttttct agtatcaatg ataagacaca
     4741 agaaagtatc actgggatca aagtcattaa aacatttgga caagaaaaag aagatctagc
     4801 ggattttgaa gaaaagattg aagatgcaat tattaaaaac aaacgagtca attttttaga
     4861 ctccttattt gatccattca ttaccttgat tatcggtctg tcttatgttg caacaattat
     4921 tttaggtgga aagtatgtct tggaaggcac gatctcgatc gggcagatgg tctcatttat
     4981 tagttatatc ggtatgcttg tttggccgat gtttgcgatt ggtcgattgt tcaacgtatt
     5041 ggaaagagga aatgcttctt atgatcgcgt caatgaactt ttgcatgaaa agacgcatat
     5101 cgtggaacaa ctgggtgcag tgcagacccc ggcaaaaggc gagctgaatg tagctatttc
     5161 ctcttttaat tatccgaaag aagaatcacc agcattagaa caaatcaagt ttgcgatcca
     5221 agaaggagaa acattaggta ttgttgggaa aactggtgcg ggaaaaacga cgatcatcaa
     5281 attactgatg cgtgaatacg atgattatca agggaaaatc caatttggcg gacgttcgat
     5341 caaagaatat tcattgaatg ctttattagg atcaatcggc tatgtgcctc aggatcactt
     5401 cttgttttcg atgaccattc gagataatat ccgtttttct aatccaaaac tttcagaaga
     5461 agaagtagag catgcggctt ctttagcatt tatcaacaat gaaatcaagg aattaccaaa
     5521 aggttatgat accttagttg gagaacgtgg agtctcttta tctggcggac agaaacaaag
     5581 gatttcgatt gctcgagcat tgatcaaaaa tcctgaatta ttaatattag atgatgcact
     5641 ctctgcagta gatgccaaaa cagaagaagc tatcttgcat aatttaaaag aaataagaaa
     5701 agagaaaaca actatcattg cagctcaccg tttaagtagc gtgatgcatg caaaagaaat
     5761 cattgttgtc gatcaaggga aaatcattga acgaggaacc catcatgagc tgcttgcact
     5821 aggcggctgg tatgaacaaa tgtgggagaa acagcaatta gaagcgaaga tagaaggagg
     5881 cgaggcctga tggatgaaaa ttatcaatcg gaatggacaa aatcgattcc acttaaagaa
     5941 cagaaaaaga tcatcaaacg actgatgaag ttcgccaaac cttttagaag aacgttcatc
     6001 gttgctatct tatttgcgtt tgctttgtct gtgatcaatg tcctattgcc aaggatcatc
     6061 caaactttta tggatgatca tctggctaaa cagtcggcta cgacacaagt tattttgttt
     6121 tttgctggta tgtacttatt tggagtcata gtaaaaagta tcatttggtt tttccaatgg
     6181 tatttgtatt ccatggcctc attgaagacc tatcagtata ttagggtaaa attatttgaa
     6241 aagctgcata cactaggtat gcgttatttt gatcagacac cggcaggatc aaccgtttct
     6301 cgagtgacga atgacacaga aacgctattt gaattttggt acgtcttttt gatggtattg
     6361 actgggatct ttgcagtcgt ttcttcattc cttgccatgt ttcaaatcaa tggagaaatt
     6421 gccttgtgga ctttggtgtt tttgccgatt ttaggaatcg tcatctggta ttaccagaaa
     6481 ttcagttctc gtatttaccg aaatatgcgg gaaaaattaa gtcagctgaa cacgaaattg
     6541 aatgaatcga tttccggcat gcgtattatc cagcagtttc gccaagaagc tcgtttagct
     6601 aaagaatttg aacaagtgaa caatgagtat ttagacacgc gttatgcgat gatcaaaacg
     6661 aattcgattc tgttaagtcc gatcatcaat tttctatatg cattggcgat tgcgttggtg
     6721 ttgactttgt ttgggatcga tgcgttgcat tctcccgtag aagttggact gatctatgca
     6781 tttacgacct atgtccaggg attttttaat ccaatgtctc aaatgatgga ctttttgagc
     6841 atcttcacag atgggatggt tgctggtagt cgtatcttga agattatgga tacggaagaa
     6901 tatgcaccac aacaaaaccc tggagcagat caaatgatta cttcaggtaa gattgagttt
     6961 cgcaatgtaa gcttttctta tgatggagag cacaatgtat taaacaatat ctcttttgtt
     7021 gctaatccgg gagagaccgt tgcattagtg ggacacaccg gaagcggaaa aagctcgatc
     7081 atcaacgtat tgatgcggtt ttacgaattt tatgaaggtc agatattgat tgatgatcat
     7141 gacattcgag aatatccaat ggaagagtta cgtaagaaaa tggggctggt cttgcaagat
     7201 gctttcttgt tttatgggga tatcgcagga aatattcgga tgatgaatcc agctatcaca
     7261 gacgaacaga tacgccatgc ggctgagttt gttcaagcaa acaaattcat cgatgaatta
     7321 ccaaaaggat atcactcaaa agtgatcgaa catggtgcca gctattctag tggacaacga
     7381 cagctgatca cttttgcgcg aacaatcgtg actgatccta aaattctagt attggatgaa
     7441 gcaacagcaa atatcgatac tgaaacagaa ggattgatcc aagaaggatt ggcaaaaatg
     7501 cgtcaaggac ggacaacgat tgcgattgcc catcggctgt caacgattcg agatgcagaa
     7561 ttgattttag ttttagacaa aggtcatata gtagaacgcg ggaatcatga aacacttcta
     7621 gcgcaaaatg gtttgtatgc agatatgtac aaactgcaaa gcagtggtat ataaaagatg
     7681 ttgtgacagt agaattttga cctaagcact agagtgaaaa taaaacatag cttctcatat
     7741 ttttcatctg tgagagttag tgtcgtagtc accagattta aaaaaagatt cgacagctag
     7801 tcagaagtgc ctaatagcca ctaagaaagc gttgacaaaa gcatttgctt tcgataatat
     7861 aaagaaaacg atacaacttg gatagtgatt gcctgatgca agctaaacct gatgagtctc
     7921 ccatggtttc atggacggct ttttgggttt ttctttttgt tggctcttcg tcaatgagtg
     7981 ttggtgaaga aattcaatag aataatcgag atactcacac ggctagacag ctatcttgtc
     8041 tagccgtgtt gttgttctgg ctttagtcag ttgggtagtg ttcttagttt tcttgaaata
     8101 ttttcctcga tataaaaaga ttcgttctcg gtagttttga aagtttctaa agccataggc
     8161 aattcgtttt agtactttga tatggttgtt caaacattct atagggccgt tggaataggg
     8221 aactcgcaac gctcgtttga tttctgttcg atatttcttg aaggtcgtga acactggttg
     8281 atagtgctct ggcaactcct tgtagtcttc ttttaggagc gcgacgaatt caggaacatc
     8341 ttgtcttctg atagcggaaa gaaaaacctg gtagacttcg tagcctcgct ttaaggagtc
     8401 atcataatat aatagccgat cgactatctc cgcttctgtc agatgatctc gaaatgacgg
     8461 acgccagtag cgatgctgac cattcaattc ccacgcattc ttttgaagta gtctccagta
     8521 tttctttaag tgcttcgacc gacgatcccc ttttttaaag gtcttcatta cttgaattcg
     8581 gtggttggta aaggcccgac cgatgtgttg gctaatatga aagcgatcgg cgacgattcg
     8641 ggcattcgga aaacactctt tcaccaatgt gcgatagggt gtatagaaat ctgaaaccac
     8701 tagacgtact tgttcacgga cttttctagg gtagcgcaag aaatagtcgc gtaaaggatt
     8761 gagttgccga ttttccacaa tatcaatcag ttgatgggtc ttgccgtcca tcatgacaaa
     8821 gctcatggct cccgagacgt ttttcaccga tttgaattca tcgaaacaca ccacttctgg
     8881 taacggctgg ttcaaagaaa cggttttagg ccgaaggctg cgaagtattc gaatgacagt
     8941 ggtcggagaa atgtgcttca tacgtgcaat caaagacata gaaataggct cacttaatag
     9001 ctcaagaatg gcttgtttga ctctgcgggc aatggagcag cgacgatcgc taactgaatc
     9061 ttctgctaaa aaagtctttc cacagtgttt acatttgaag cgctgtttgt taatccgcac
     9121 aatggtcttg tagttactga catcattcaa taagatggat acttttttcc agccccattt
     9181 aatgatcgtt tgcttatttt gatagtggca atggaagcat tcctctggtt gataggtcaa
     9241 tgtgccatca aaaacaaaac atgtttcgtc attaatgcgc tctttgcgaa aggcatcttc
     9301 atgaaaggta agatttaggt ctagaatatc tagtaactct ttggtaaact ctgaatagga
     9361 catcttgaaa cactcctttg aatggttttc gtcgacttta ttctaaagga tttcaaggtg
     9421 tctgtttgcg tttattagaa aaaagaaaaa gtattggcaa cagaaggcgt caccaacact
     9481 agatattata gatccttttt gttttggata cagccctata catcatggaa aggagcaaaa
     9541 catgctgatt gagaaagtac tgaataacaa cgtcgtaata accagggatg aaagaaatca
     9601 ggaaatgatc gtgatgggaa aaggtttggc attcaaaaag aaagtgggtg acccgatttt
     9661 tgactcatgc atcgacaaaa aatttcagtt gacaaatgac gggctttcac aacagttcca
     9721 agaattggca caagcgattc ctcttgagta cttagaaatt tcttgtgaaa tcattgaata
     9781 tacaaaagag gctctacaag tccagttgaa tgattctgtg tatattgcat tgacggatca
     9841 tttgtatacg gctatcgaac gtcacaaaat gggaatattt gtaccaaatg tattgctgta
     9901 tgatatcaaa caactatttc ctaaagagta tgccatcggg aaaaaaacag tgaagaaaat
     9961 ctcggataaa taccacatca agttatcaga agatgaagcc ggatttatcg cattgcattt
    10021 agtcaatgca caaggcattc aaagccagca agacaatacc tacctgttta ctataacaat
    10081 acaggatatt ctaaatatcg tccgctatta ctataagatt acatttgatg aagattcagt
    10141 ccattttttt cgattcgtca cacacttacg tttttttctg acacgcgtcc tagatggaga
    10201 aaaatcagaa gtgggagaag tttctgagga attgtttcag gttattcaaa aaaaatataa
    10261 ggatacgttt ggttgcgttg agaaaatagc agacttttta gccgagacgt tcaactacca
    10321 gatgtccacg gacgaaaaaa tgtatttaac gatccatact gcgcgtttag tgcatgagaa
    10381 tcgttgtaaa taaaaaaagg aggataaatt aacaagaacg tatgaaataa gggtagtgac
    10441 attcagttgg ctaaaccttc cactaataaa ttggagggaa tagaaatggg aaaataccaa
    10501 gaattagcga gaaaaatcgt agaaaatgtc ggcgggaagg aaaatatcaa tggtttgaca
    10561 cattgtatca caaggcttcg tttcaaatta aaaaacgaag aaaaagcaaa tgatgagatc
    10621 ttgaaaaata tggacggtat tgtaacggta atgcgagcgg gagggcagta tcaagttgtc
    10681 attgggaatc atgtgccagt cgtgtttgaa gaggttataa aagcaggaaa ccttactttt
    10741 gatgaggctg tttcaacaga aaaaatgaga ccgtttgata tgcttattga tggaatatcg
    10801 ggctgtttcc agccattcct tgctatccta gctgctggcg ggatgattcg tggactgaca
    10861 gcattccttg tcttcttagg cgcgtttgac cgcggttctg gcacatttgt tatgtttgat
    10921 aatatcggtg attctgtatt ccaatttatg cctgttatta tcggtttaac agctgcccgt
    10981 aaatttaaag taaatgaatt cgtagggatg ttgcttggcg cagcattaat gaatcctagc
    11041 ttgtcgctgg aagctttgag tggtgcagca gaagcaccac taacgaccat attttctggc
    11101 actatttttg aagcacctat ttatcaaaca gtattcggca ttccctggat tgcgcgtaac
    11161 tacgcttctt ctgtcattcc cattatcttt attgtgttgt tagctagcca aattcagaaa
    11221 ccaattaaaa agttagtacc tgagatgatc gcgaatttct tcgttccatt cttcaccgtt
    11281 cttattacaa tgcctttagg ttttttactc gttggaccag tattcacatt cgcaactgat
    11341 attttaatgg ctggatttga aacactttta gcactttcgc cagttattta tggagcaatc
    11401 gtaggcttct tctggcaaat tctggtgatg tttggtctcc attgggcaat cgtaccaatg
    11461 ggattgatgc aattttctgt gaatggttgg caaaatatta tgacacctgt tgcagtagtg
    11521 tcttttggac aaactgcagc acttaccgca ctctacttta agcttagaaa tccaaaagac
    11581 aaagcaattg caataccagc cattgtttct ggtattgtgg ggattacaga gccagctatt
    11641 tatgggttta cattaccacg taaaaaaata tttattttta cctgtgtcgg tggtgcgtta
    11701 gggggcgcgt atagtgggtt aatgaattta acttcttgga atcaaggtgg actaggcatc
    11761 tttacaattc ccaactatat tagaccagat ggtgatttaa cagatgtgat taatgtattg
    11821 attgggatcg ccattgcgat ggtggtatcc tttacgctga cttttttctt ttggaaggat
    11881 gaagcaggtg aaacagatga tatacagaaa aaatcaggta aagaaattgt aaaaacaccg
    11941 atacaaggac aaatcgctcc actaaatgca gcaaaggatg cagcttttgc acaaggaaca
    12001 ctaggtcgag gaatcttgat ctaccctgaa aaaggagaag tacgtgcccc ttttgacgga
    12061 acagtcatga ccctgttccc gacgaaacag gcaattggaa tggtttctga aacagggctg
    12121 gaattgctga ttcatgtcgg attggatact gtgcagttgg aagggaaata ttttgaaagc
    12181 ttagtgcagc aaggataaag agtgaaacaa ggcgatctgt tgctacgctt cgacaaaaag
    12241 aaaatcgaaa aggaaggata cagtttagaa acacctgtga tcgtcaccaa ttacacggat
    12301 tatttggata ttttggaaaa ccaaggggag acggtcgggc cagacgatgc acttatcacc
    12361 gcactgacct gaacggttag gtgaagaatg gactaggctt aactattctt tttattccac
    12421 ttctttattt tcaaaattga aaggctcttt catgatggct gagctgatag ggcgtttatc
    12481 gaatttttga ccgacagaaa ttagatggac taaattctgt tgataatttt ctgcaaaaac
    12541 acaactatat aacacgtcta gaagataaca aattgatgta ttgatcgtaa aattaccaat
    12601 ttttgaatac agtcgctcgc gtgtcgtaag tcgcaaagcg gctgtactca ttgcagatag
    12661 cgttgaatca ccgatactgg tcaaagctaa aattggaaca tgattttgtt tcaatatttc
    12721 tgcggtacga aggatcacat tgttttcacc cgtataagaa atcagaatcc cgcacatatc
    12781 actcgtgcaa ttgtacgctt catagaatga ttcaccaaaa gtggtgacaa tcgtgacatc
    12841 cattttgatg cgcttcattt tcagcatgaa atcttgagaa atcaaagtat tcgagttact
    12901 ggcgaaaatc acgatttttt ttgcttgaag cattagttgt ttggcttttt gcagttggtc
    12961 atgatgaatg agagaaagtg tatcatgaat cgtcatctgt tctaaagaag ccattttatt
    13021 tgcgatcgtc ataataccgt ctgtggtgga aaaaggaaga ttcgcatcta cgtcttgaaa
    13081 attcccttca agataggctg tttcagctaa aaaagcatta cgaaaactga cccagccatc
    13141 aaaacccatt ttttttgcta cacggatgag tgtagagggg tggacataac atcgctcagc
    13201 aatcgcttgg atggtcattt cgccaagtgc tggagaatcg cttaagagaa actggatcac
    13261 ttcattttct gaaggagaaa aggagatttc tttgattttt tcacgtaata acatgtagat
    13321 accttcttct tattttttta cgtaaattat aacttttttg aaaatgattt gtaaacggat
    13381 ttatactata taacttaaaa tagacatttt ttgacaagat atttacaaaa atccactaga
    13441 aaacagtaaa ttttgtaaat gttactggaa agaaacagat ttctattgtt tgttttgttt
    13501 acaaaaaaga taatgaaagt gtaaaaaagt aaaggagtga gaacatggca aaaggaatca
    13561 aaatcgctac gattggtgga ggcagcagtt acacccccga gttgatggaa ggatttatca
    13621 aaagatatga ggaattaccg atacgagaaa tctggctcgt agatgtagaa gaaggaaaag
    13681 aaaagcttga gatcgttagt cagatgtctc agcgtatgtg ggatgcttct ccgtatgaag
    13741 tcaagatcta tgcaactctg gatcgggaag aagcattgaa agatgcggat tttgttacga
    13801 ctcagtttcg tgtcggtcaa ttagatgcac gaatcaaaga cgagcggatc cctagttatt
    13861 atgggatgat tgggcaagaa acaaatggtg ctggcgggat attcaaagct tttcgtaccg
    13921 ttccagtcgt tttggcaatc gttgaggaca tgaagcgttt atgtccaaat gcttggctga
    13981 tcaatttcgc gaacccaagt gggatggtga cagaagcagt tatcagatat ggcaaatggg
    14041 ataaagtgat tggattatgc aatgtgccag tgatggcgat gatgacagaa ccagcaatgc
    14101 ttggcaagaa aaaagaagag ctgatctaca agtttgccgg tctaaatcat ttccattggc
    14161 acaaagtagc agataataaa ggaaatgacc gcacggcaga attgattgat cgtttatacg
    14221 atgaagagaa tggattaccg aaaaatatct ttgatatccc gtttttcaaa gaacaattaa
    14281 aacaaatgaa catgatccct tgtggctacc accgctatta ctatcgtgaa gaagaaatgc
    14341 tggaacatgc tttagaagaa tatcaaacga ttggtacaag agcgcagcaa gtgaaagaaa
    14401 cagaagcaga gctatttgaa ttatacaaag atccagaatt agaccataaa cctgaacaat
    14461 tgcaaaaacg aggtggcgct tattattcag acgctgcctg tgaaacgatt gcttcaatct
    14521 atggaaataa agaaacacag atcgtggtat ctacaaagaa tgatggagct gttcctgacc
    14581 tgccggcaga ttgtgtagta gaagtcactg cctatgttgg cgcacaagga gcgagaaatg
    14641 tagcgtttgg ttctcttcct gctgctgaaa gaggctggtt gcaagtaatg aagaatatgg
    14701 aattgctgac gatcgaagca gctgtgactg gtgattatgg gacagcttta caggcgttta
    14761 cgatcaatcc acttatacga tcaggaaaga cagcaaaacg gatcatggat gagttgttta
    14821 ttgcacacca gcagtattta ccgcaattca aggagacaat cagccgatta aaagaagaag
    14881 gaatcgaagt tcaagatgaa ctggcaagag aattatcagg taatacacat ataatggagg
    14941 aagtataatg ggattcagaa aagatttttt atggggcggt gctacagcag ccaatcaatg
    15001 tgagggcggt tatgatgaag gtggacgcgg actagcaaac gtagatgttg tgccaatcgg
    15061 aaaagaccgt tttcctgtta tcaccggaaa gaaaaaaatg tttgaatttg atgaggatca
    15121 tttttatcca gcaaaaattg caatcgatat gtatcatcgt tataaagaag atattgcttt
    15181 gtttgcagaa atggggttca agacttatcg aatgtccatc gcctggagtc gtatttttcc
    15241 aatgggggat gagaaagagc cgaatgaagc tggcttgaaa ttttatgagg atgcctttaa
    15301 agaatgccaa aagcacggaa ttgagccact tgtgacgatt acgcattttg attgtccaat
    15361 gcatttgatc aaagaatatg gtgcgtggcg ttccagagaa ctcgttggtt tttatgaaaa
    15421 tctgtgtcga gtcatcttca atcgctataa aggacttgtc aaatattggc tgacattcaa
    15481 tgagatcaat atgatccttc atgcaccatt catgggcgca gggctgtatt ttgaaaaagg
    15541 agaaaatgaa gaacaaatca aatatcaagc ggcacatcat gagttggttg caagtgccat
    15601 cgcaacgaag attgctcatg aagtagatcc ggagaacaaa gtaggctgta tgctggcagc
    15661 aggagcatat tatccataca cttgcaatcc tgaagatgtt tgggcttcta gaaaatcaga
    15721 tcgagaaaat tatttcttca ttgatgtcca gtcacgagga gaatatcccg cttatgcatt
    15781 gaaagaaatg gagcgaaatg gcattcagat cgaaatggaa ccaggggatg ccgcattgct
    15841 gaaagaacat actgttgatt ttatctcttt ttcttattat gcttcccgag tttcgactac
    15901 cgacaacgaa ctcttggaac agactgcagg aaatatcttt gcttctgtca aaaatccata
    15961 tctgcaagca agtgaatggg ggtggcaaat tgatccatta ggcttgagaa taacgatgaa
    16021 tgatatttat gatcgttatc aaaaaccatt gtttattgta gaaaacggct taggtgcagt
    16081 cgatacgcca gatgaaaatg gttatgtgga agatgattac cgaatcgatt acctggcagc
    16141 gcatatccag gcgatgaagg atgcagtaga actagacgga gtcgatctat taggctatac
    16201 gacttgggga tgtattgatt tagtatcagc tggtaccggt gagatgaaga aaaggtacgg
    16261 attcatttat gtcgatcgtg ataaccaagg aaatggcaca ttagcccgtt caaagaaaaa
    16321 atcattcaac tggtataaaa aagtaattga ttcaaatgga gaaaatcttt cgaacgattg
    16381 atcaatgatt tataaaagtc tattgttttt cagcggattt ttcgagtata ataaagctat
    16441 tcgagaaacg caagcagaac aatagacttt ttttcgcatt ggctgtaaag tatgcttact
    16501 tgattaagta aaggagaatc tacatatgta tgatgtaatc gttattggcg caggtcctgc
    16561 tgggatgact gctgctttat atgcttcacg ttcaaactta tccgtattga tgatcgaaca
    16621 aggtgcccct ggcggccaaa tgaacaatac ggcagaaatc gaaaattatc ctggattcga
    16681 ttcgatcatg ggccccgatc tagcttataa gatgtatgaa agtgtctcaa gatttgggac
    16741 agaaaatgct tatggaatcg ttcaagatat caaggatcac ggcagccata aagaagtcat
    16801 ctgtgaagat aaaagttacg aaggaaaaac agtcattatc gcaacaggat gtatccaccg
    16861 taaattaggc gtacctggcg aggaagaatt tgctggacga ggcgtttctt actgtgcagt
    16921 ctgtgatggt gcgtttttcc gtaacaaacg tctagtagtc atcgggggtg gggactcagc
    16981 agtagaagaa gccatctatt tgacacaatt tgcttctgaa gtagtgatcg tccaccgtag
    17041 agatgaatta cgtgcacaaa agatcatcca agaccgtgca tttgcaaatg aaaaaatttc
    17101 ctttatgtgg gatacagtcg ttgacgaaat cgttggaaac gaaatggtag tgacaggtgt
    17161 gaaagcacgt aatgtcaaaa ccggcaatga atttgattta gcagcagacg gagtattcat
    17221 ctatgttgga ctggatccat taactgcacc ttttagagaa gcaggtttga cgaacgaagc
    17281 tggctggatt ccaacagaca acgaaatgaa aacgaatatg ccaggcgttt ttgccatcgg
    17341 agatgttcgt gaaaaagatt tgcgacaaat cactacagct gttggtgacg gcggtattgc
    17401 tggacaacaa gtgtataaat acttggagtc tttagaagaa acaacagcat aagtttaaaa
    17461 agagtagaag aacgggttca attgttcttt tactcttttt tttcgcgtga aatttactga
    17521 atctgattta tgcgaacacg tccaacacct tttgataaaa gaatcctttc ttgatttaag
    17581 cgttttttgg tcctcatact ttcatatcta ataagtgaat gctatactta ttaagaacca
    17641 tatttcagaa agaggtgtta ttttcatgtc ttgggaacaa gtgtatgaac aatgggtaca
    17701 tgaagaaaat ttagaagaaa acttaaaaaa acaattaaat gatctgggtg aagatcctga
    17761 aaaacttgaa gatgcttttt atgcaccgtt ggaattcggt actgcaggta tgcggggaat
    17821 cttaggacct gggatcaatc gaatgaacat ctatacggta agacaagcaa cagaaggact
    17881 agcacgtttc atggatacac aaggtgaaga aacaaaacgc cgaggtgtcg ctatcgctta
    17941 tgactcacgc catcagtcac cagaatttgc aatggaagca gccaaaacac tagcacatca
    18001 caatatcccg tcttatgtat tcgaaagtct gcgtccaaca ccagagcttt cttttgcagt
    18061 tcgtcatttg aagacgtttg cgggaatcat ggtaaccgca tctcacaacc cagcggctta
    18121 caatggatat aaagtctacg gagaagatgg cggacaaatg cctcctgcag acgcagatgc
    18181 attgacgaaa tatgtccgtg aagtcagcaa tccgctaaaa gtcgaagtat tatctgacga
    18241 agaagctaaa catagcgggt tgatcacgat catcggagaa gaagtggacg ctgcttatct
    18301 agaagaaatc aaagcagtga cgattgatcg tgaattggtt gaaacaatgg ggaaagattt
    18361 gaaacttgtg tacacgccac ttcatggaac agggaaaatg ttgggcgaac gtgcgttgaa
    18421 acaagctgga ttcgaacaat tcgtactagt tcccgaacaa gctgtggcag atccagattt
    18481 cactacggtc aaatcgccaa atccagaaga acattcagct tttgaatatg ctatacgact
    18541 tggagaaaaa gaaggagctg acttgctgat tgcaacagat cctgatgcag accgtttagg
    18601 cgcagcggtt cgtttgccag atggttctta tgaagtattg actgggaacc aaatcggagc
    18661 attgtttgct caatatattt tggaagcaca tcaatcaaga ggcactttac cagaaaacgc
    18721 agcggtattg aaatcaatcg tttccagcga attgcctaca gcaattgcgg aacactacgg
    18781 tgctaccatg ttcaatgtgt tgacagggtt taaattcatt gctgaaaaaa tccaacaatt
    18841 tgaagaagac cattcacata cttttatgtt tggattcgaa gaaagttatg gttatttagt
    18901 taaacctttt gttcgcgata aagacgcgat ccaagcattg cttttattag cagaagtagc
    18961 agcttactat aaaaaacaag gcaaaacgtt gtatgacggc ttgcaaacga tttttgaaac
    19021 ctatggctat ttcgcagaaa aaacgatttc tgtgacaatg agcggacaag aaggttctgc
    19081 gaaaatctct gctttgatgg aaaaattccg taaagaagca ccgacagaat ttgccggagc
    19141 aaaagttatt caaacagaag actttaaaga attgacgaga acagaccgtg aaggaaacgt
    19201 agaaaaacta acaacaccgc catccgacgt attgaagtat acattggaag aaaatggctg
    19261 gatcgctatc cgcccttcag gaactgagcc gaaaatcaag ttttatattg gtgtaaaagg
    19321 aagctctaca gaagacgcag ccgaaaaagt agcctcttat gaagcgatta tcaaaaagat
    19381 gacagaagaa taaaaaactt gagactgatg gaaaaagtgg taaactttag aagtcagtct
    19441 tttttcaagt tggaggtgaa tggattgcca gacacgcaaa aatcaaaagt agagaaagtc
    19501 agtcaattat tcaaaatgtt gagtgatccc actcgtctta aaattctgct atatctgaaa
    19561 gacggggaac aaaatgtgac agcaatcacc caagcagtgg aaatggagca gtctgctgta
    19621 tcgcatcaac tacgtttatt aagagaaaat catgtcgtca agtctcatcg cgagggaaaa
    19681 gcgattttgt atagtcttga tgattctcat gtactggata ttttgaacca gacactcaaa
    19741 catgtggaac atcaataacg ataggtgaaa atagataaac actggagtgt gacaacgaag
    19801 aaatttcgtt gtcacactcc agtgtttttt aagaaaaaga caaaaatgat taatcgcttt
    19861 tttctgttgt ttcagttcca taataactat gatcttctag gtctaaagca ttcaaaataa
    19921 gcgaagccgt ttcttcaata gataaagatg ccacattgat cactacacat cctagttttt
    19981 cataaagatc attcgcaaaa tcgagttcag ctctaatttt ttcgatatcg gaataagcag
    20041 tatcagggtt taatccgtaa gagcgcatcc gttctttacg gatattattt aaaatatctg
    20101 ggttattcgt tagtcccacg atttttttag gatcgatttc ccacagctgt ttgggaatat
    20161 gtgcttgggg aatcaaaggt aaattagcaa cttttaaatt tttatttgct aaaaacaagc
    20221 tcaaaggcgt tttggaagtt cgggatacgc ctagcaaaac gacatctgct tctaaaaaac
    20281 cacgaggatc tttcccatca tcgtatttta cagcaaattc cattgctttg atccgtttga
    20341 aatagttctc attcaataaa tggagggcac caggttgccg aattggcttg ataccagtta
    20401 aacgttcaat ttctgatatc ggtggcgtca tcacatcgaa actaaataat tgatgttctt
    20461 cacaaaaaga acgtgttatc tcgatcagtt cttgattgat taatgtatgc aggacaagtg
    20521 ctttttcttc taatgcatct tgcaatgcct gccttaatgt tttttcatct gtcacgaacg
    20581 ttctgcggaa taggttgaac tcaacggtag gatactgagc catagtagct tgcgctagtt
    20641 ttgtcgcagt ttctccagca gagtcggaga tgacaaaaaa agtaacgatt tctgtagaat
    20701 cggaagacat ggataaaacc tcacttgcat tttttttatg tttattatac catactctag
    20761 aatgcgtact tcgtaatcat tttgatttgg aggaataagt catgaaaaaa cagacattga
    20821 tcgaacaatc attagaaaca ttgaaaaata acggttttaa atatactaaa aaaagagaag
    20881 cattgttaac ttatttagtg aagcgtaacc gctacgtatc tgctaaagaa gtttttgact
    20941 atatgaatca ggaattcaaa ggggtaagtt atgatacgat ttaccggaat ctccatgatt
    21001 ttgcagagat cgatttactg gaagaaaccg atttaaatgg tgaaatgaag tttcgttttc
    21061 attgctgtca gggggaaatc ggccatcacc atcattttat ctgtacagtg tgcggaacaa
    21121 cgaaagaaat ccatatgtgt ccaatgaatt atttcgaaga acagctaggt ggatgcacga
    21181 tcgaagggca tagattcgag attttcggaa gatgtgaaaa ttgtcaataa ggatttaaat
    21241 aaaataacat ttgataattt aaaaaaaaag caagatttcc ttgacggtca aaacagcatt
    21301 agatataata tttacaggac agtcttgttt tttgagatat atttcaataa caattacggt
    21361 tactttttaa gctcggaggg agggaattaa catgtcaaaa acagtcgttc gcaaaaacga
    21421 atcacttgac gatgctcttc gtcgcttcaa acgttccgtg tcaaaagcgg gtactttaca
    21481 agaatctcgt aaacgtgaat tctacgaaaa accaagtgta agacgcaaga aaaaatctga
    21541 agcagctaga aaacgcaaaa aattctagtt ctgtgatgaa ttggagttgg tagtgtgtca
    21601 ctactaagta gattaaacga tgacatgaaa gcagcgatga aagcgaaaga taaggaatct
    21661 ttacaagtca tccgaatgat caagtcatct atacaaaacg agcagattaa agaaggtcac
    21721 gacttgacag aagaagaaga actaacggtg ttgtctcgcg aaatgaaaca gcgacgtgat
    21781 tctttgcatg agtttgaaga agcaggacgt gacgatttag ctgaaaaagt aaaaagtgaa
    21841 attgtaatag tcgaaaaata tatgccggaa caactttccg acgaagaaat tcgacaactt
    21901 gttcaagaag caatcactca aactggtgct tcatcaatga aagaatttgg caaagttatg
    21961 ggtgcaatta tgcctaaagt caaaggaaaa gcagatggaa accaagtgaa tgcgattgtg
    22021 aaagaactat tacaatctta attttatcat ttaaactgcg gacagtgatt gtccgcagt
//
LOCUS       DASHWW010000043        21642 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.043, whole genome shotgun sequence.
ACCESSION   DASHWW010000043 DASHWW010000000
VERSION     DASHWW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.043"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            144..542
                     /locus_tag="U2R64_001798"
     CDS             144..542
                     /locus_tag="U2R64_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEM8918618.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="U2R64_001799"
     CDS             526..1221
                     /locus_tag="U2R64_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEM8918619.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1805..2692)
                     /locus_tag="U2R64_001800"
     CDS             complement(1805..2692)
                     /locus_tag="U2R64_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEM8918620.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2877..3716
                     /locus_tag="U2R64_001801"
     CDS             2877..3716
                     /locus_tag="U2R64_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEM8918621.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3912..4886
                     /gene="sgrA"
                     /locus_tag="U2R64_001802"
     CDS             3912..4886
                     /gene="sgrA"
                     /locus_tag="U2R64_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HEM8918622.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5184..5540
                     /locus_tag="U2R64_001803"
     CDS             5184..5540
                     /locus_tag="U2R64_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918623.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFASQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5543..6700
                     /locus_tag="U2R64_001804"
     CDS             5543..6700
                     /locus_tag="U2R64_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918624.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6726..7166)
                     /locus_tag="U2R64_001805"
     CDS             complement(6726..7166)
                     /locus_tag="U2R64_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEM8918625.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7326..7832
                     /locus_tag="U2R64_001806"
     CDS             7326..7832
                     /locus_tag="U2R64_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8918626.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8000..9913
                     /locus_tag="U2R64_001807"
     CDS             8000..9913
                     /locus_tag="U2R64_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEM8918627.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVEKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9918..10919
                     /locus_tag="U2R64_001808"
     CDS             9918..10919
                     /locus_tag="U2R64_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8918628.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11121..11327)
                     /locus_tag="U2R64_001809"
     CDS             complement(11121..11327)
                     /locus_tag="U2R64_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HEM8918629.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11973..12821)
                     /locus_tag="U2R64_001810"
     CDS             complement(11973..12821)
                     /locus_tag="U2R64_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8918630.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12820..13887
                     /gene="gnd"
                     /locus_tag="U2R64_001811"
     CDS             12820..13887
                     /gene="gnd"
                     /locus_tag="U2R64_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HEM8918631.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13889..14890
                     /locus_tag="U2R64_001812"
     CDS             13889..14890
                     /locus_tag="U2R64_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HEM8918632.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14887..15171
                     /locus_tag="U2R64_001813"
     CDS             14887..15171
                     /locus_tag="U2R64_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HEM8918633.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15204..16001
                     /locus_tag="U2R64_001814"
     CDS             15204..16001
                     /locus_tag="U2R64_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8918634.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16015..16848
                     /locus_tag="U2R64_001815"
     CDS             16015..16848
                     /locus_tag="U2R64_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8918635.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16866..17723
                     /locus_tag="U2R64_001816"
     CDS             16866..17723
                     /locus_tag="U2R64_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8918636.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17745..18254
                     /locus_tag="U2R64_001817"
     CDS             17745..18254
                     /locus_tag="U2R64_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8918637.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18291..18692
                     /locus_tag="U2R64_001818"
     CDS             18291..18692
                     /locus_tag="U2R64_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918638.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18804..19157
                     /locus_tag="U2R64_001819"
     CDS             18804..19157
                     /locus_tag="U2R64_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918639.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19191..19634
                     /locus_tag="U2R64_001820"
     CDS             19191..19634
                     /locus_tag="U2R64_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEM8918640.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19651..20736
                     /gene="uxuA"
                     /locus_tag="U2R64_001821"
     CDS             19651..20736
                     /gene="uxuA"
                     /locus_tag="U2R64_001821"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEM8918641.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20729..21442
                     /locus_tag="U2R64_001822"
     CDS             20729..21442
                     /locus_tag="U2R64_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8918642.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7458 a         3322 c         4510 g         6352 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 ttatttctca tttaaacgat gtattcccta acctctaata catccttgta actctgaagt
     1381 tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt
     1441 tcgtgtttct ctagtataac agaataagag gaacaagtcc agaagggata tttttagtct
     1501 tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg
     1561 gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga
     1621 tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt
     1681 tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa
     1741 taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat
     1801 ttgtttattt gaatatattt tttacataag gatctttaat agttacattg tcttttttca
     1861 tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa
     1921 ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca
     1981 tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag
     2041 aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat
     2101 tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag
     2161 cttgaacaag cttggagaaa ttttcccctt catttgcttc tttttttgct ttatctgctt
     2221 cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag
     2281 cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca
     2341 gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt
     2401 ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg
     2461 aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata
     2521 gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc
     2581 cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg
     2641 cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct
     2701 tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct
     2761 gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt
     2821 ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga
     2881 tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt gttttaggaa
     2941 ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa
     3001 ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg
     3061 tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt
     3121 tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt
     3181 tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt
     3241 ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc
     3301 atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc
     3361 ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag
     3421 gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct attggtgctc
     3481 atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag
     3541 aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact
     3601 ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt
     3661 tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga
     3721 tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa
     3781 aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc
     3841 gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga
     3901 gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa
     3961 ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat
     4021 ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag
     4081 tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg
     4141 atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga
     4201 ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga
     4261 gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt
     4321 tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg
     4381 aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaagta
     4441 gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag
     4501 gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca
     4561 tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata
     4621 atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca
     4681 acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa
     4741 aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga
     4801 acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc
     4861 gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa
     4921 cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag
     4981 ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac
     5041 aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga
     5101 aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata
     5161 atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag
     5221 tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata
     5281 tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat
     5341 cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa
     5401 aagtcgagtt tgcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa
     5461 cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc
     5521 ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac
     5581 tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga
     5641 agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca
     5701 ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca
     5761 tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt
     5821 gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt
     5881 gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc
     5941 aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt
     6001 tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga
     6061 aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg
     6121 ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc
     6181 aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga
     6241 ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc
     6301 tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata
     6361 ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca
     6421 atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga
     6481 acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta
     6541 tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca
     6601 acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa
     6661 aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc
     6721 caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc
     6781 aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct
     6841 tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa
     6901 gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga
     6961 acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc
     7021 aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg
     7081 ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca
     7141 gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa
     7201 taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca
     7261 cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca
     7321 caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt
     7381 ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca
     7441 aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag
     7501 tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt
     7561 ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg
     7621 aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga
     7681 ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa
     7741 cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg
     7801 ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa
     7861 tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat
     7921 ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct
     7981 cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt
     8041 ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat
     8101 ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga
     8161 aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt
     8221 tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac
     8281 agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg
     8341 gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta
     8401 cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt
     8461 aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagaaa aagagattat
     8521 caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt
     8581 gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta
     8641 tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga
     8701 tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt
     8761 tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg
     8821 gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac
     8881 ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg
     8941 gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt
     9001 attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc
     9061 aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc
     9121 cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct
     9181 tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac
     9241 gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt
     9301 acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt
     9361 agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca
     9421 tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga
     9481 aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga
     9541 aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc
     9601 gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc
     9661 agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga
     9721 acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca
     9781 aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct
     9841 tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag
     9901 aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca
     9961 tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct
    10021 tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg
    10081 atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt
    10141 acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc
    10201 ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt
    10261 tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac
    10321 cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa
    10381 aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg
    10441 cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc
    10501 atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt
    10561 tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat
    10621 gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag
    10681 ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa
    10741 atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag
    10801 tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt
    10861 tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa
    10921 gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt
    10981 tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga
    11041 tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc
    11101 ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat
    11161 ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt
    11221 tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa
    11281 atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc
    11341 ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga
    11401 tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa
    11461 tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa
    11521 atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg
    11581 atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca
    11641 aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa
    11701 aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa
    11761 ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca
    11821 atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct
    11881 gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt
    11941 tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt
    12001 cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat
    12061 agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct
    12121 gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct
    12181 tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt
    12241 gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa
    12301 gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc
    12361 aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag
    12421 acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac
    12481 ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc
    12541 tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg
    12601 atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga
    12661 aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt
    12721 actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg
    12781 ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat
    12841 aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa
    12901 aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag
    12961 ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga
    13021 ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca
    13081 agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa
    13141 tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata
    13201 accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa
    13261 ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa
    13321 atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc
    13381 ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta
    13441 gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg
    13501 atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta
    13561 caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg
    13621 gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta
    13681 agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg
    13741 ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca
    13801 caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga
    13861 catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc
    13921 cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt
    13981 tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg
    14041 attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa
    14101 agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc
    14161 agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac gaaatgctgt
    14221 agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc
    14281 aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa
    14341 caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg
    14401 taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga
    14461 aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg
    14521 tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca
    14581 gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc
    14641 gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga
    14701 agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca
    14761 tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt
    14821 cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat
    14881 aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat
    14941 ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa
    15001 agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt
    15061 ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct
    15121 gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg
    15181 gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg
    15241 gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata
    15301 aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta
    15361 taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag
    15421 atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg
    15481 aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc
    15541 attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc
    15601 tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa
    15661 gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc
    15721 gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc
    15781 gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc
    15841 tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg gctgaattta
    15901 ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac
    15961 agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa
    16021 acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc
    16081 tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc
    16141 gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg
    16201 atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca
    16261 gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt
    16321 gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact
    16381 tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga
    16441 tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt
    16501 gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc
    16561 gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact
    16621 gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt
    16681 gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc
    16741 gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac
    16801 aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat
    16861 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
    16921 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
    16981 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
    17041 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
    17101 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
    17161 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
    17221 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
    17281 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
    17341 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
    17401 tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag acagcgattg
    17461 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
    17521 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
    17581 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
    17641 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
    17701 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
    17761 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
    17821 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
    17881 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
    17941 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
    18001 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
    18061 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
    18121 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
    18181 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
    18241 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
    18301 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
    18361 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
    18421 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
    18481 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
    18541 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
    18601 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
    18661 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
    18721 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
    18781 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
    18841 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
    18901 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
    18961 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
    19021 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
    19081 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
    19141 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
    19201 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
    19261 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
    19321 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
    19381 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
    19441 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
    19501 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
    19561 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
    19621 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
    19681 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
    19741 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
    19801 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
    19861 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
    19921 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
    19981 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
    20041 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
    20101 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
    20161 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
    20221 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
    20281 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
    20341 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
    20401 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
    20461 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
    20521 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
    20581 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
    20641 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
    20701 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
    20761 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
    20821 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
    20881 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
    20941 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
    21001 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
    21061 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
    21121 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
    21181 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
    21241 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
    21301 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
    21361 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
    21421 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
    21481 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
    21541 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
    21601 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tc
//
LOCUS       DASHWW010000044        21371 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.044, whole genome shotgun sequence.
ACCESSION   DASHWW010000044 DASHWW010000000
VERSION     DASHWW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.044"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            131..505
                     /locus_tag="U2R64_001823"
     CDS             131..505
                     /locus_tag="U2R64_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEM8918643.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="U2R64_001824"
     CDS             complement(619..1248)
                     /locus_tag="U2R64_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8918644.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="U2R64_001825"
     tRNA            complement(1382..1454)
                     /locus_tag="U2R64_001825"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="U2R64_001826"
     tRNA            1668..1741
                     /locus_tag="U2R64_001826"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="U2R64_001827"
     CDS             complement(1879..2043)
                     /locus_tag="U2R64_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918645.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="U2R64_001828"
     CDS             2338..3666
                     /locus_tag="U2R64_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HEM8918646.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="U2R64_001829"
     CDS             3868..4701
                     /locus_tag="U2R64_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HEM8918647.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="U2R64_001830"
     CDS             4717..5454
                     /locus_tag="U2R64_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEM8918648.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="U2R64_001831"
     CDS             complement(5609..6577)
                     /locus_tag="U2R64_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEM8918649.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="U2R64_001832"
     CDS             6809..7642
                     /locus_tag="U2R64_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HEM8918650.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="U2R64_001833"
     CDS             7676..8515
                     /locus_tag="U2R64_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8918651.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="U2R64_001834"
     CDS             8541..9101
                     /locus_tag="U2R64_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEM8918652.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="U2R64_001835"
     CDS             9300..11021
                     /locus_tag="U2R64_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEM8918653.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="U2R64_001836"
     CDS             11186..12328
                     /locus_tag="U2R64_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEM8918654.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="U2R64_001837"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="U2R64_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEM8918655.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="U2R64_001838"
     CDS             14128..14775
                     /locus_tag="U2R64_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEM8918656.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="U2R64_001839"
     CDS             15168..17813
                     /locus_tag="U2R64_001839"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEM8918657.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="U2R64_001840"
     CDS             18123..19436
                     /locus_tag="U2R64_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEM8918658.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="U2R64_001841"
     CDS             19426..20079
                     /locus_tag="U2R64_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8918659.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="U2R64_001842"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="U2R64_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEM8918660.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..>21371)
                     /locus_tag="U2R64_001843"
     CDS             complement(20700..>21371)
                     /locus_tag="U2R64_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEM8918661.1"
                     /translation="NKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDC
                     QGSVAGQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEA
                     TKQKFEQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALM
                     KELNEIEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNIT
                     VNFLI"
BASE COUNT         7173 a         3559 c         4386 g         6253 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt cctctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat t
//
LOCUS       DASHWW010000045        20941 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.045, whole genome shotgun sequence.
ACCESSION   DASHWW010000045 DASHWW010000000
VERSION     DASHWW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.045"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            168..362
                     /locus_tag="U2R64_001844"
     CDS             168..362
                     /locus_tag="U2R64_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918662.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..929
                     /locus_tag="U2R64_001845"
                     /pseudo
     CDS             631..929
                     /locus_tag="U2R64_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1026..1460)
                     /locus_tag="U2R64_001846"
     CDS             complement(1026..1460)
                     /locus_tag="U2R64_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918663.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1692..2402)
                     /locus_tag="U2R64_001847"
     CDS             complement(1692..2402)
                     /locus_tag="U2R64_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEM8918664.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2392..3252)
                     /locus_tag="U2R64_001848"
     CDS             complement(2392..3252)
                     /locus_tag="U2R64_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEM8918665.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3257..3895)
                     /locus_tag="U2R64_001849"
     CDS             complement(3257..3895)
                     /locus_tag="U2R64_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEM8918666.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3910..4209)
                     /locus_tag="U2R64_001850"
     CDS             complement(3910..4209)
                     /locus_tag="U2R64_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8918667.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4252..5736)
                     /locus_tag="U2R64_001851"
     CDS             complement(4252..5736)
                     /locus_tag="U2R64_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEM8918668.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5756..6217)
                     /locus_tag="U2R64_001852"
     CDS             complement(5756..6217)
                     /locus_tag="U2R64_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8918669.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="U2R64_001853"
     CDS             complement(6235..7302)
                     /gene="ulaG"
                     /locus_tag="U2R64_001853"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEM8918670.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7520..8290
                     /locus_tag="U2R64_001854"
     CDS             7520..8290
                     /locus_tag="U2R64_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8918671.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8563..9390)
                     /locus_tag="U2R64_001855"
     CDS             complement(8563..9390)
                     /locus_tag="U2R64_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918672.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9958..11193
                     /locus_tag="U2R64_001856"
     CDS             9958..11193
                     /locus_tag="U2R64_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEM8918673.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12192..12452)
                     /locus_tag="U2R64_001857"
     CDS             complement(12192..12452)
                     /locus_tag="U2R64_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEM8918674.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12479..13780)
                     /locus_tag="U2R64_001858"
     CDS             complement(12479..13780)
                     /locus_tag="U2R64_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8918675.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14072..14530)
                     /locus_tag="U2R64_001859"
     CDS             complement(14072..14530)
                     /locus_tag="U2R64_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8918676.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14543..15874)
                     /locus_tag="U2R64_001860"
     CDS             complement(14543..15874)
                     /locus_tag="U2R64_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HEM8918677.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15885..17327)
                     /locus_tag="U2R64_001861"
     CDS             complement(15885..17327)
                     /locus_tag="U2R64_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8918678.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17314..18078)
                     /locus_tag="U2R64_001862"
     CDS             complement(17314..18078)
                     /locus_tag="U2R64_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HEM8918679.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18182..19057)
                     /locus_tag="U2R64_001863"
     CDS             complement(18182..19057)
                     /locus_tag="U2R64_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8918680.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19312..19396)
                     /locus_tag="U2R64_001864"
     tRNA            complement(19312..19396)
                     /locus_tag="U2R64_001864"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19360..19362),aa:Leu,seq:caa)
     gene            complement(19414..19485)
                     /locus_tag="U2R64_001865"
     tRNA            complement(19414..19485)
                     /locus_tag="U2R64_001865"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19451..19453),aa:Gln,seq:ttg)
     gene            complement(19495..19567)
                     /locus_tag="U2R64_001866"
     tRNA            complement(19495..19567)
                     /locus_tag="U2R64_001866"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19532..19534),aa:His,seq:gtg)
     gene            complement(19629..19713)
                     /locus_tag="U2R64_001867"
     tRNA            complement(19629..19713)
                     /locus_tag="U2R64_001867"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19677..19679),aa:Leu,seq:caa)
     gene            complement(19734..19804)
                     /locus_tag="U2R64_001868"
     tRNA            complement(19734..19804)
                     /locus_tag="U2R64_001868"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19770..19772),aa:Cys,seq:gca)
     gene            complement(19850..19921)
                     /locus_tag="U2R64_001869"
     tRNA            complement(19850..19921)
                     /locus_tag="U2R64_001869"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19887..19889),aa:Gln,seq:ttg)
     gene            complement(19933..20005)
                     /locus_tag="U2R64_001870"
     tRNA            complement(19933..20005)
                     /locus_tag="U2R64_001870"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19970..19972),aa:His,seq:gtg)
     gene            complement(20008..20081)
                     /locus_tag="U2R64_001871"
     tRNA            complement(20008..20081)
                     /locus_tag="U2R64_001871"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20047..20049),aa:Trp,seq:cca)
     gene            complement(20088..20168)
                     /locus_tag="U2R64_001872"
     tRNA            complement(20088..20168)
                     /locus_tag="U2R64_001872"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20132..20134),aa:Tyr,seq:gta)
     gene            complement(20170..20245)
                     /locus_tag="U2R64_001873"
     tRNA            complement(20170..20245)
                     /locus_tag="U2R64_001873"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20210..20212),aa:Phe,seq:gaa)
     gene            complement(20281..20353)
                     /locus_tag="U2R64_001874"
     tRNA            complement(20281..20353)
                     /locus_tag="U2R64_001874"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20318..20320),aa:Asp,seq:gtc)
     gene            complement(20363..20435)
                     /locus_tag="U2R64_001875"
     tRNA            complement(20363..20435)
                     /locus_tag="U2R64_001875"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20400..20402),aa:Val,seq:tac)
     gene            complement(20451..20522)
                     /locus_tag="U2R64_001876"
     tRNA            complement(20451..20522)
                     /locus_tag="U2R64_001876"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20487..20489),aa:Glu,seq:ttc)
     gene            complement(20537..20626)
                     /locus_tag="U2R64_001877"
     tRNA            complement(20537..20626)
                     /locus_tag="U2R64_001877"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20590..20592),aa:Ser,seq:gga)
     gene            complement(20666..20739)
                     /locus_tag="U2R64_001878"
     tRNA            complement(20666..20739)
                     /locus_tag="U2R64_001878"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20703..20705),aa:Asn,seq:gtt)
     gene            complement(20749..20864)
                     /gene="rrf"
                     /locus_tag="U2R64_001879"
     rRNA            complement(20749..20864)
                     /gene="rrf"
                     /locus_tag="U2R64_001879"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6601 a         4390 c         3332 g         6618 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa tcatgtgttc attttttata ttagttcgaa tttgcaaaaa attgtatttg
      901 ataaagaggt gagtaaaaaa ataaaatagc tgagcattgg aggatagatt gagtgatact
      961 aagtctatcc tcttgttttt ctaaagaact aagctagaat tttttctttt gtacgttatt
     1021 atatgttatt tgtcattacc aaaaagcacc ttttttcttc tagtatctat gacataagaa
     1081 ataccaccca tttcctttac ttgaacaaat cctactgatt cataaaattt ttttgttttc
     1141 tcagtatcat ctgtcaataa ttcgatttgg actggtccat aactagtgat cttctccaaa
     1201 gcttcattca aaagcacttt gcctattcct tggcgctgat acctcggatg aatgaggata
     1261 tcttgaataa atgcgatcgt cgcaaaatca gtgatccaac gaacgattcc gataatcttc
     1321 ccttccccat tacgctttat cagagattca gattgttcaa atgctctagc taaccttgca
     1381 gtgtcttttg tgtaattcgt ccaaccaacg ctcttatata attcagaaat ctcatcgatc
     1441 ataagggaat caatattcat ttttttcttc ctttcttata caattctccc tctaataata
     1501 cagttctttg actatttaat ctatcacata taactctcct gtaaagattc tctcgattcc
     1561 ttaaaattcc tctttccttt tagaatgcat actttttgat aaataaaaag gttgtgataa
     1621 attttcttca caacctctgt ttctctctat caagtgttat cttttaattt tctaccctta
     1681 ccctagcatc tctattgccc gtagtatgca tactttccat gtttgcgaaa ataatgttta
     1741 tctagtaaat attgcgggat ttcacatata ttggggttga tcagctcgtt ttctttggcc
     1801 atcagacaaa tttcatctaa gatcaaactg ttttctactg ctttcatagg tgaatccccc
     1861 catgtgaacg gtccatgtcc atagacaagt actccaggga cttcgtttgg atctaatttt
     1921 ctttccttaa acgtctcgac aatcacattc cctgtatgaa cttcgtaagc ttctcttact
     1981 tcttctttcg ttaattggcg tgtacaagga accttaccat aaaaagcatc agcatgagtc
     2041 gtgccataag ctggcaaatc gcgtcctgct tgcgcccaca tgacggagtg cgtggaatga
     2101 gtatgagtaa tagcagttat atcttcaaaa gtttgataca aaacaacatg tgtggggaga
     2161 tctgaagatg gttttaagct atcttcttct attatatttc ccgacaaatc tgttaccacc
     2221 atttgatctg cttgcatgca ttcatatctg acaccgcttg gcttaatgac gatgactcct
     2281 agctcacggt ccacttcact cacattgccc caagtcaatt tgactaatcc gtatcgcggc
     2341 aatgccagat ttgcttcaag gacacgttgc ttcattgctg caattttttc ttcacaagac
     2401 atcatagcca gcctccttca atttagaact taagtagtct tttgcctgct ggatttctct
     2461 tcgaaagtct tggctttttt cactccacat ttcaatcaga aatgttccat cataatctag
     2521 acgtttcaaa tgtcttaata atccaagaaa atcaacacaa ccgctaccaa aaggaacatc
     2581 acgaaactgg cctgaatatt cttttgttac agggtaagta tcttttaagt ggatagcagt
     2641 gatataatcg atccctttct caagttctcg agccggatta ttttccggcc atgcggacaa
     2701 attgcctagg tctggatata cttgtagaaa aggtgaatga atctgttctt tgatttctaa
     2761 aaattttgaa atggagttca taaatggatc atccatgatt tccacggaaa gaatgatgcc
     2821 atatttagaa gcttccttta cgctttcttt tattccttcg ataaagtctt ctctggaatt
     2881 cattgatttc tcttcataat aaacatcgta tccagctatt tggattactt tgacgcttag
     2941 attatgcgcc aaatggattg cttttttcat tagttgtttc gctgcttttt tcttttctgg
     3001 atcagcagaa ccaaacggaa atcgccgatg cgcacttaaa caaatcgaat ggatacgtac
     3061 accggagctg aacatctctt ctctcagctc agctatcttt tcttcagacc aatctaatcg
     3121 tgctaaccgc tcatccgtct catcaatcga catctcgata aaatcgaagt ccatttcttt
     3181 tacaagggaa aaacgttctt tccatgaaat atctttgggt aacgcttttt cataaatccc
     3241 aatttgagcc atttccttac ccccagatac gaatgatctc atctttgaag ttttgtgcgg
     3301 ccttcatcgg atcatttgct gctgtaatac cacgaccagt gataaaggta tacacatcga
     3361 tcccttcaaa taagtgtaat gtgtgtggat ttaatccacc agttacagaa acattaaagc
     3421 ctagttcaat cagttttttg atcttcgata aatctttttc accccaagtt tcaccagata
     3481 acagcgcatc acggctttga tggtagatta cctgccggat accgatgtta tgccaatcca
     3541 tggcttgttc aaaagtccaa ttgccgtaga gttctacttg caattcacct atttcttttt
     3601 gtgctgcctc catagttgga atcgttgcac aacaaatgac tgtcatccag tctgctcctg
     3661 cttttgcaac attactcgcc actgttcctc cagcgtctgc acatttcgta tcagcgacta
     3721 gttttttatc tgggaacata ctgcgaatac agcgaatcgc tttttgtcct tcctgtaagc
     3781 aaagaattgt gcccacttca ataatatcta ctacatcacc aactttcata acatctccta
     3841 atgcatgttc taagtcattg tgatctaacg caatttgcaa attcggcctg ctcatcttag
     3901 ttccttcctt tacttgtttt tttggtacca ctttgtttca gcaaattttt cactgatttc
     3961 tttgactgac atcacatttt tgataccgat aactgtaact ccttttttct ctgcctgagt
     4021 aaacatattc aaaaaattga ctggcgtaaa aactacatcg tattggccag ctgaactttt
     4081 tccctctgaa atggcacaat gatggatttt ggtaattggt acgtttagtt ctttcattgc
     4141 tttttccaca cttctcatca tcatcaagct tgttcctgat ccatttgcac acgatactaa
     4201 aattctcatc ttaatccctc cattatgagt gttgtctaat cagattttct tttatactct
     4261 ctgcttttct gcatatgtgt catagtcttc tacaatcaaa aaataaccat caggattttt
     4321 ccgatattgt aactgcggaa tagccaataa accaatgaca actacggcaa ttccagcata
     4381 acctaggact ttcatgatta ctgtaaacaa tggccaagct gttgcccagt cgaacatccc
     4441 gatataacca ccgtatgttg acatcccaat ccatgtagcg aataatgctg aaccgcctac
     4501 ttgtatgatt cctgaaagaa acgggaacag gcaagcggct ttgaatccac ctcggttatt
     4561 ggcataaact gctataacgg cattatcaaa gaacaacgga atgaaaccgg ctatgacgat
     4621 cgttggtgat ttcaataaaa tcagtaaacc aatcatcaaa aactgtccca aagcaccaaa
     4681 caagaaccca atcgttaccg catttggcga accaaagcca aaagtagcag ctacgtcaat
     4741 tcctggaaca gctcctggta aaatcgtgtt tgagattcct tggaaagatt gagttagttc
     4801 atcgacgaat gtccgaacac ctaattgcaa gatcgccaga tataccgcaa aatttaaaga
     4861 agtcgtcata atgtagaata agaaactctg cccttcttgc atgaattgcg cttgaatcaa
     4921 ataatctttg cctagtacaa tcagaatgat cccaaagaaa aatagcatga gtaacgaagt
     4981 agcaaccata ttctcattga aaatcgacaa gaatcctggt aatttgatat cttcaatttt
     5041 tttgtcttgc ttgattgatc tatttttctt ttcatcccgc tttttcatcc actcagctaa
     5101 ttttgcaaat ataaagattc cgaacatttg ctgatgtgcc actgcaaatc cggcaccttc
     5161 tgtcaattcc tgcgtgattc ctactgttaa gttagaagct actgtccaat aacaacctaa
     5221 aatcagtccc ataaaaatca atgcttgtat cctacctaga tcaggaaagc aaaacagtaa
     5281 aatccaaaaa gcggtagctg cttgttgaac ctgaacgttt ccggtagtga aaacggaacg
     5341 cagtttcgta tatttctgaa aacggactaa taagatattt aaaacaaatg caatcagtaa
     5401 taaaatcatc acatctccaa aggtacggcc aaatgtctcc attaatccag catccacagc
     5461 attttgtcca aaataaggat ctgtaaccat ggcatccaaa ttgaaccgtt cctttagtcc
     5521 aaccaagatt ggccgaaaat tattgaccaa accaccagag ccaacagtca aaataaagta
     5581 accgaccgtt gcctttaaga atccagcgat gcattcatga agcgggcgtt tcagcaaaat
     5641 atagcctaat aacacgataa aaccaatcag gtatgctggc tgcgtcaaga tatttgttgc
     5701 aaaatacgtc caaatgctta acaaaaattc ccccatcttt tttctcctct atcaattaat
     5761 tatattctgc catcacaact tggtaatcat cgatggagtt cgtagagatg agacgctcaa
     5821 ccaatccatc tgtcattaat aattcggata atttttggat attttctaga tgttcttctg
     5881 gatcttttgc tgcgagtgta aaaaacaaac tagccgtttt ctcctcattc tccccttcac
     5941 tttcaaaacg gattggctgt ttcaacttgg taaatgaaat agctgttcca aaaacaccat
     6001 cacttttttc tgaagaatgc ggcattgcta cttgaggtgc gatcacaata taaggaccgt
     6061 atttttctac acaatggatg atctcctcca catacgtttc atcaataatt tccttatcga
     6121 tcaatacaag acagctttcg gcgatagctt cacgccaatc cgtgatttct ttatctgggt
     6181 aatgaatcaa ttgatggtca aaaaagtatt tcagcaagaa actccccttc tttcttataa
     6241 aaacgacgga aacggtgtat cattttcaat cgagaagaca tcttcaaatc ctcgataaaa
     6301 attaaactca agatcatctt tgtttgtcgg atagatgaat ttcccgccta cttgccagat
     6361 ataaggttta aatccatact tcaggcgatc ctttttgaat ttccaaattt cagtgatctc
     6421 ttttggatca gccataaaat tagaccaaat atcgtagtgg acaggaatca ctacttttgc
     6481 attcaatgac tccgccatgc gcagcatatc aacagaagta actttgtctg ttatccctcg
     6541 tgggttttca ccataggccc ctaaacagac atcgattttg tgttcattac catgtttggc
     6601 aaataaattg gagtaatgtg aatctcctgc atgataaaga ttccctcctg atgtttcgaa
     6661 taaatagttt actgcaattt gatccatctc ctgaggcatt tttcctttta atacctcttc
     6721 tggatcttca caagtgacca acgctgtccg atcaaacgct tctaaagcta ctacattgat
     6781 gtctttgatt ttgactgcat cacctggctt tactgtaatc gttttttctt caggaattcc
     6841 ccatttttgc cacgtgcgaa ccacttcttt tggcccaatg aatgttgctt caggacaatt
     6901 ttgatgaact gctgcggctg tatggatatc tagatgatcg gaatggatat gtgtaacgat
     6961 taaagcgtct acatttttta tcgcaaaagg atcgattacg aaaggctgag tacgtaaatt
     7021 aggctgcata ttttgaacgc cactcatacg catcatctga tggccttttt tcatcatgcc
     7081 attcccatga ctacgttttc ccgtcccaca ccatagatca cataaaatat tcgttccttc
     7141 atgacttttc agccaaattc ccgtacagcc cagccaccac atagcaaaag ttccaggatc
     7201 cactacttct gtttcgattt cttcattcaa gtatgtgccc cactcaggaa atgtttctac
     7261 taaccacttt tcttttgtta cttcattgac agttttactc atttgcttgc tccccccata
     7321 tcgttgttcc aacttacaag taaatattaa tgtgtatcag catccatgaa aaccctttta
     7381 tatgaccgtt tgttttttat atgattttct ttcagtaatc aatgattgtt tcagtataat
     7441 aaagacagat atgaatgttt aaatgaacaa ctagtcaaat aaatccatgg atcaagatgt
     7501 ccctcaggag gcaaaagtca tgaaaaactc acttgtcaat attgaaaaac gtcaaaaaga
     7561 aattttggaa ctgcttcagc agactgaaca actatcaact ttcgaattag ctgaatccct
     7621 tgatgtatct attagtacga tacgaagaga tttaaattta ttagaagaaa aaaacgagat
     7681 catacgcaat tacggttatt gttcttataa ttacaaaaac cagactgatt ttgatcaatc
     7741 tggtcctgaa aggattaaac aagcgattgc cagagaagct agtaaataca ttaacgatta
     7801 tgatacgctg tttatcaatt ctagctcgac tgcgttgaaa acactggatt ttcttcaatc
     7861 taaccatttg acagtcatta caaacaacgt gaaaatcaat tactctccgc acaaagataa
     7921 ttgtagttat attttaactg gtggagagat gcgctttcca aaagaagcac tagtgggcga
     7981 catcgcatta aatacgattt cttcagtcaa tgcagacatt tgtatcattg gctgtagcgg
     8041 agtcgatgta gtacatgggg tcacaacaaa gatattaaat gaatcaacga tcaacgaaat
     8101 gatggtcaac aagacaatca aatgtaagat tttagtcgct gatcatcgaa aaatcggact
     8161 gacatcaaag ttcaagattg ctgatatttc agtctttgat tatttgatca ctgataaatt
     8221 ttgttctgaa aaagtattag aggagatcag aaatacgggg ataaaaacca ttcaagtaga
     8281 ttcattttaa gaaccaggac gtaaatatgt aaataggatt atcaaaaaaa tgaataacaa
     8341 atttatcgat aaatgaaaaa cacgctacgc tcaaattgat aaaggaatcc caagatgtat
     8401 ccatccaatc gataccatca taatctattg cttcttttat aaccgttata tgttgcctaa
     8461 ataggaatca aacaatatcg aaaaaaggag gtatgacaaa agtcacacct ccttttttcg
     8521 aataaacggt attcaaatca gaacactgat ttcacaacca ctttatttca ggtcgttttc
     8581 aatcaccttt accgcgtaat catttccgtt gaaacgcgct attttttttg cgtccatata
     8641 tctttctaaa taatcatctt ctcctaattg cttatggcaa gaagcaattt cataaagcaa
     8701 gtattccaat gcataagtcg atttatgttt cttattatac tcaataccct tctcacataa
     8761 ttggattgct ttatcataat cctcgatttt acggtaatag gtggcgatat cataatatac
     8821 aatgcagacc atcagattat caaaatcagt ctcactcaat attttaagtg tacgctccac
     8881 ataaactttc gcaaaatcta attctccttt tgacaagtag atcattgcca cgtttgcagc
     8941 tgcttgtaag tgatggatat ctgtttcggt cgtttgttcc aacacttgat taaaataaaa
     9001 taatgctgca tctggttttt tcgcataaag atgatcaagc agtccttgat aaaataaaat
     9061 ttgatttaaa agatcagaat tacttacttt ttcctgatcg atcgtttgta aaattttata
     9121 agattcttgg tattttgata cagaattcaa tgattgaatc tcatttattt ttttcctgat
     9181 tttgtcttct tctgtttcta ctaatatatc ggagatctcg acattcagct ttttgcaaag
     9241 cgcacttaag atattgatgc ctggcgacat attcttgttt tcgatattgc tgacagttgc
     9301 ttgttcacaa atgccttctg ctaattgtac ttgtgttaac ccctttttct ttcggtattc
     9361 ttttagtaat gctccatcta ctttaatcaa aacaatttcc ttccctttaa aaaattattt
     9421 ctcctttata tcatacacaa aaaaaagttc taaacaacca aaaatgttta gaacagaata
     9481 aaaattttaa ttttaaaata atattcaaat taaacaactg gcgtatctgc tccttgattt
     9541 ctttttgtgt tatctgaata attatcgttt acagttataa cacatagtga aaattgtcat
     9601 ggcgagaaag tctaagaata tttttaaaca taactatttc tttcttacgt gtgtataatg
     9661 acgacagcac acctatcaat taatataatt attttatttt tttatgttct catgtttatt
     9721 tttaatgaca caacttctcg tatttatctg gcacaacata taaatcgatc aaaaaattgt
     9781 tgcgtgtttt tttgaaaatt ggagtttcaa cttgattaca aaatttaaat ttagaagttg
     9841 tgaaaacagc gagagacagt ttaatattca aaatatacat aggctactcg aacgctgtgt
     9901 tttttagtat actagtaaga aacgaaggga tagactcatt ccaataagga ggatttcatg
     9961 aagacaattc tttttgctcc tgcagtattc aatttagctg agacaacacg aatgattgag
    10021 gttgccaaag ctatgaaaga ccgttattac tgtgtattct ttggcttttc taaaactttt
    10081 gctcctttga tcacagaaag tggctttgag tatcatttac tagcgccgat ccttacgaaa
    10141 aaacaagaag aacaaatcat aaaatttgac cagttgcgta cacttaaaaa cccttttacc
    10201 aaagaaatgg ttgcctctcg tatcactagt gaacagagtc tgattgctaa gtttgagcct
    10261 cgactgattg tgacaggttc gaatgtgaca atttttttat cggcccgcaa taaaaagatt
    10321 cctttagtat atgttaaacc ctatgctttg agtgaacctt tttttcaatc agagcatgcg
    10381 ctgatgcccc acgagttacg tttcttcggc cctttaagca atcccctttg gcactggaca
    10441 aaaaagcgta tagtaaatac ccgatggatc cccaatgcct tcaaacacgc tgcacaaaaa
    10501 gaaatgcttc ctttaccaaa aacaagttta caaatgatgg atgctgatct aaatctcatc
    10561 acaacgccta aactattttt ggaagaagaa cagctgccgg aaaattatcg aatcgttggt
    10621 ccaatttttg ctaagctcag tacttccttg cctgaagaag tgctaacttt tatacagcga
    10681 aagcaacaag aaagaaaacg tattatctat ttcgcaatgg gtagttcagg caatccgcgt
    10741 atgttacgca aaattttgtt cttcttacaa aaacaaccgg atctagcggt tattgcacct
    10801 attgactatc tgcttgatga cattcaatct gactcagaag atcttttaat aacagaatat
    10861 ctgtctagtc atcttttgca tgaattcatt gatttttctt ttatccacgg cggggaaggg
    10921 accgtccaaa ctgcctgtga atccggcaaa ccgtttatcg gtgtggggat gcaatttgag
    10981 caaagctgta atattgacta ttgtgtaaaa tacggaaacg caatcgccct cacaaaacca
    11041 gtgactgaaa gaaaactgca gattgctctg cgcgaagttt cttcacccaa gattcgtcag
    11101 caggcacgca cgctgcaagc cgtttttcca ataaatggtc cacaacaagc aattcaagaa
    11161 atcgaaacct tcctgagcaa ccacccaata tagtttcaag tagaaaaagc ttttttaata
    11221 gagactcatc agtaatttcg ctattcgaga cccagacagt gaaaatacaa aaaaagtaaa
    11281 tagtggattg aaaagttaga gttacttaaa ttacggtgtc taaaaaacac aaaatcatcc
    11341 ttaaaataaa agatctgacg ctatccaaat gagcataggt agcgtctgcc atttattctt
    11401 agtcaaattc tttgacacct ttctctggtt ggatcatctc aacgtttctt caaaagaaag
    11461 accataataa ttaggcaaat acattttctt aaaatgtgtc atatagatct agaagcatcg
    11521 ctttgtagag atttgtgccg ctagtcccct caacaattac taaatcaaat gtaggattta
    11581 ccactttatc tttgataatc aacctccctc ttctgttgag acaatgatct cgcaatccga
    11641 tgcatactcc tatataaact gccagcaatc cccacatatt gagtagatca tgtcagaatg
    11701 ttctatgtcg tcagcaacga tacactaaaa gtcacgttca ccatgactga ttgctattcc
    11761 cagcacaatt atttctatac acgtttcatg atttgaataa acactcacat catacatatt
    11821 accattcata caccatactg cagcccctac tatatggttg taagctccca aatctatatt
    11881 tgacttgatc actttggtag tagatctact aattctaaat ccattgctga taaaatttcc
    11941 attttttcct ccttctttct gccaaaacag ttaaaacaat aataatcttt atgtaaaaaa
    12001 gggctgtgac aaaagccttg tcacagtccc atattccgaa taaacggtgg tcaaaagctt
    12061 gcatctgcgg taataagttc aaccaaacga aaaataagcc aacatttcac aaaaatttaa
    12121 gaagcaattt tcgtaaattt cttcttattt cttgaagcta accacttctg ttacaaccac
    12181 ttttagaaca tttaaagctt cgatgtgaca aaccatctat gctgctcgat cataaaattg
    12241 atagcaaaaa ttccacaaag tacatatgtc ccccatgaaa acaaaacatt catatgcggt
    12301 acaatgatct ttggaagaat cacgatcaaa aatgatgcca gtgcccaaat ccatcgattg
    12361 atttgaatat gatatgtagc tagcatattc aatataaggt gactagccgt taataaaaag
    12421 ataaaaacaa aaaataaaat cagccaatac attgtttccc accttctaaa aaccaaactt
    12481 agacagtctg gacttcgttt tctccacgac tttgttcatc tgacagcatc tttttatcat
    12541 aagcttttac aaatggataa tagataataa atgctatcaa tgtgttgatc atgatcaaga
    12601 taacaacacg ccagtcattt cctgctgaaa gataaccgcc gattggagct ggtaatgtcc
    12661 atgttggcaa aacagtaaat ctattgacca tttctaattt gactgcaaaa taactgataa
    12721 tagtcaaaac taaaggaact aagttgaacg ggatgaacat gtaaggattc aacatcatag
    12781 gagctccaaa aattatgggc tcattgatat tgaagatacc aggaataata gaaaaacgac
    12841 caacctcttt caagaatttt gatttacaga agaatataaa caaaacagat accacgatcg
    12901 ttgctcctgc accaccaatt gttaccgtcc attgataaaa ctgttcagga gcgatatagg
    12961 gtaattgggt ggcagctgta ccatctgcca atgcctttgc attctcatcc aacatgatca
    13021 gccacattgg acgaacaaca gcccctacaa tactcatgcc atggatacca aatgaccaca
    13081 acaaatggat caaaaacatt ggtagtaaaa caccaagcaa attattccct aaaatattgg
    13141 ttaaaggctc gaataacgat aataaggcag cgtttacatc aaagcccgcg acgcttcgaa
    13201 tcagccaagt aattgttaaa atgactgcac ctggaatcaa tgcctcaaaa ctacgggcaa
    13261 cagcaggtgg cacttgttct ggcattttga tagtaatatt tcgattttta aagaaacgat
    13321 atacttccac tgcaaaaatc atagataaga tccccgcaaa catcccagat gctcccaaag
    13381 aactcatagg taagacccag ccaagaggtg cctcttcagg agttaaaacg tttacaggaa
    13441 cttgtaacat aaagaacgtt cctaaagata atataccacc tgtcacacta tctaatccat
    13501 atgatttagc tagatccgaa cccataacaa aagttgcata aatagccatc aatcccatcg
    13561 tcatcctaaa gggtaaaaca atcgttgccg aataaggggc aataaattca ttccatccag
    13621 gaaacggtaa attgataaag accataaaaa atgtcccaat caaaatcaat gacaatgttg
    13681 aaacaacccc attacgaatt gctaataaat gacgctgtgt accaattttt gccattggtg
    13741 ggacaagttt ctcttcgacc catttcatca gcttttccac taaaaccact ccttttcaat
    13801 aaaatatgaa ccattcattg catgacaacg caaagaatgt tcataactaa ttatataatt
    13861 aagaaatttt atttcaatat attctcttaa ataatcaaat ttatttttaa gaatcctgaa
    13921 aataagtttt ctaaatcata ggagcaacaa aaaaattcga taattaacaa aaatcaaaat
    13981 gattaaatct agtgattgaa acatatcatt tcaaaaaaat tttgtaaatt cacccataaa
    14041 tatcacccta tttaactttt ttcatcgtac actaaaattc aaaacaacta tctttaatct
    14101 ttacttcttg gttttgtttt aataaatttc cttcaaaaat gcctggagaa actacaatga
    14161 tcaccgtatc tttttgtgct tgctccaact tcttcaaatc tataatagct aacagtgtcc
    14221 cttcttttac ctcctggtta ctttcaaccc gtatctgaaa cggacttcct tcgagttcaa
    14281 ctgtatctaa acccatatgg atcagtattt ttctgccaga ttcactttcg atcgttatgg
    14341 catgtcgggt aggaaatata ttatcgatta ttcctttaac tggcgcatgg atatatccat
    14401 catgattcgt tatagcgtat ccaactccta tcatttttga agaaaagacc tcgtctttta
    14461 ctgctgttaa tggaataatt tgaccactag ctacagcttt tagaatgttt cttgttttaa
    14521 agaaatgcac tttttatcac ctctacttta atgctggcca atattttttg tttactttga
    14581 tcatttcatc tagtattttt tttgcgactc tggcatttgg tacggtttga ttcaatgtaa
    14641 atgcttgtaa agctttttga taagaacctt caaagtaagc atctactagt aacttctcta
    14701 ctgcaacttg tgcctccatc aatcctttat gaaaatcact gattggtttt cttagtgtaa
    14761 ttggctccac accagttgca ccaacatatg ccggtatttc aacaactgca tctgaccgta
    14821 gattcggaat cgccccttga ttaggaacga ttagcataaa gcgacgacga tcatcattca
    14881 acaaggaaat agctatatcg acgatatatt gtccatgctc cccaaaatta aagttcaata
    14941 cttcttccac aataccgcgg cgtattttat cagccatttc tttggtattt ttctctcgtc
    15001 catccatgac catattagca cgtgtatact ctttgtcagt atgctcaacg accatatcag
    15061 gatataagta atactctaag taattattcg ggatattact tggaaaattt ttcgtgatga
    15121 ctgacatcat ttgaaaggtt ttttgccaag ttttatctcc tatattaaaa tcggcgactt
    15181 gcatttcttt tgttattagt ttttcaataa tctctggcat aatttctcgt tgcaattctt
    15241 tatcataaat cgatgtatac cagccaaagt ggtttaaacc ataatacgta acgatccaat
    15301 tcttacgatc ataaccgtaa ttcactgcaa tcgtttcttc aattgaaata gtcatatcac
    15361 aggcattaat catttttaca ttcggatatt tacgacgaac agcttcagaa acgatcgact
    15421 ctggatttgt ataattcaaa atccatgctt tgggggcata gtcttgtata tgatcgacaa
    15481 tttccaataa acctttgatt gagcgcatcc cataagcaaa tcctccgagt ccacacgttt
    15541 cttgtcctac taatccatgt ttaagtggaa tcttttcgtc cttttctcgc atctccaatc
    15601 ctccaacacg aatttgtgag aaaacaaaat cgcgtcctgt aaaagcaagc tttggatcat
    15661 ccgttgcacg aatgcgaata tttgaaaaac cttttctttt cagcataaat ttaacaatca
    15721 agtacatatc catatttctt tcttcatcaa tatcatataa acgtatttca gataatggca
    15781 accgtttttc attgttcaaa atggcttgaa cgattcctgg tgtatacgta ctcccgcctc
    15841 cagctatagt gataatctgt tttttcatca tcatcttttc ctttctattc ttctaataat
    15901 ttattgaatt ctgccataac ataagtcact tctaagccga tgataatttg ataatttttt
    15961 tcagttggtt taatgatccc gcttatccct aattgcttga ttcgctgttc ctcgaccatg
    16021 gtgggatcca ctacctctac ccgtaggcgt gtattacaac tatagacatc caggatattg
    16081 gcttttcctc caaacgcttg tagcattttt gttgccatat attcataatt tttacttgct
    16141 aaccctaact ctgtttcttc taaggttact tcattgccaa actctgcctt agcttcacgt
    16201 cctaatgtct gaatgtttct cttattgatc aaataataaa aagtaacgta atacaaggca
    16261 aaaaagaaaa ttccgattgg aagaatcaaa atagcattgg tagcgattcg aaaattgatg
    16321 agataatcaa caatacatgc tccgaatgta aaaccaattc gtatattgaa taagtaacag
    16381 acaatccctg ctaaaccggc aaaaagtgca tggatcacgt acaacatagg agaaagaaac
    16441 atgaaactaa attcaacagg ctcagtgata tttgcaataa atgaagttcc tgcaccgctt
    16501 cccatgattc ctttgaccat ctctttattt tctttataag ctgctttata gatagctaga
    16561 catatagctg gtataccaaa catcattact acaaaaaaaa ctgataaaaa cagtccagcc
    16621 tgaggatctc cgttgataaa gcgtgtcatc tctcctctga aaacttcctt gctaggagat
    16681 gtatagcttc ctaaatcgta ataaatatac gtattcaaca catggtgcag tccaaagggg
    16741 atcagcaaac gattcaaaaa cataaatatc cccacaccta atgctcccat atcaacgagc
    16801 agttttgcaa aattatcaat cccaatttgg atgagcggcc agataaagcc caaaaaaaca
    16861 gctgcgattg tttgtagaat catcaccata gtcaatggga atttttcgcc cgcaaaataa
    16921 gaaaaaacta ctggtaattt ttgttcttta aagcgattat acgtccatgc cgctactaaa
    16981 ccggaaataa ttccaccaaa aatccccata ttcacttctg ggtccataat ttctaagcct
    17041 tttttcaagg tagcaatcgc taaaaaacca gtaagtgcag gtattccttt gtccttattt
    17101 ttgacaaaac cgattgcaac tcctatagca aataagatat ccaagtttcc aaaaacggca
    17161 tttccagctg caccaattac tgggatgttc agcatatcgt cagctgataa acgcatgatc
    17221 aatcccgcta atggcatcgc tgcaactgga agtagcatcg ctcttccaag cttctgcaca
    17281 tttgatttaa cattcatttt tattcctcct ctattaaata tcctcatatg ttactaactc
    17341 aatcaaagga tcatttttca ctttttgagc aaatgctgaa tgaattaaaa attcgacttg
    17401 gtgggtacga ggatacacaa aacttgaacc atttaacaat tcctgatcca aatacgctgc
    17461 gtgacacatg acttcgatcg ttttatcttc tctcaatatc atgagtaaac ttgccaaata
    17521 ttcttccaca ctcgtattga tttgtcgttt tttttcatca gtttctccta cgacatcgaa
    17581 acaaggctca aaataatcga catgacgaac ttcatctttt cgttcaaagt tgctccgaac
    17641 cggcaaatca tatttttttg ctaatgtaac aactacctcc tgattttcat ccaaagtatg
    17701 agtatgatga tgactgtcta aatgagttgg tatgatcccc gcatgataaa ttttttgaat
    17761 ctgagcattc cattcctgat acagttgatc tttgtcaatg ttaaatggat gctgataata
    17821 agataaggat ctgaactctc cgctttcgat aagagtatcg acagttttga ggagtggttt
    17881 gccacacgtc aatgttaaat ggactcctac acctagccta ggcatttcct ttcttagttt
    17941 cacagcatgc tcgaaacccg gcatatttgc catcaatgta gttgatgtca aaattcctcg
    18001 ctgataagca tccataatcc cataattcac accatggcta tagccaaaat catccgaatt
    18061 aaaaatcact tttcccattt cattctcctt cttttttcta ctaaaatagg cgcaaccaaa
    18121 taatcatagt ccatttacta tgtgtcattt ggttgcgcct atagatagtt acgcccttat
    18181 tttaatagat tcttgctaga tgaattgcca aatagatgat ttcattttct tgaatggcaa
    18241 gttgaaattg ctgttcgatg atatctttaa tctttagtgc tgtacaatac gctttgctat
    18301 gtttaaatgt ttcagtaaaa aaaccaatat tttctactgg cgtttcttcc tgataaatca
    18361 agcgtttaac caggaatttg atatgaacca ttaagcgatg ataagtcagt gattctttat
    18421 cataaacgtt tgaataggat ttttctagat gggacaaaat cgtggtcgtc atttctacta
    18481 tttttaagct ctttaaacta ttaggctctc ctagctcagc attaatgata tgcatagtga
    18541 tgaatcctac ttcatttgac cctaactcgg tttgatatcg atgattgatt cgctcgacca
    18601 cttctactgc tatatcatat tcatttggat aaaggaatct catttctggc aacataattg
    18661 ctgtgacatc tctatcttct ctttttcgtt gaatagcaaa ataaatatga tctgtcaatg
    18721 taatatagat atttgaatct aatggagagg agatcctagc tgttatcagt tcaatcactt
    18781 cttccgcaaa atccataaat tcgattggaa tctgcgagac tatctcactg aatcgtttga
    18841 tcttttcttt agaatctaat acaaataatt tgtcagcatc ctcaacatca aatggcttac
    18901 tcactttagc agaaaagcca atccctttcc ccatcgcaat tttttctatt ccatcgtcat
    18961 cgatcaatac agcattatga ttcagctttt tcatcacata caccgttaat tcacctcctc
    19021 tatatgataa aacaaaacaa cttgcagact ccttcataca tatttttgtc tccaaacaat
    19081 ttttaaagac aaaaaacgac ctaagaaaga accctttctt aggtcgtgcc taattgaata
    19141 gtagcaccct acataattta caaaaatagt ttaacacata ataaaagcgt tatcaatatc
    19201 ttttttactc gttttatgat aatacttgta tcgaattgat ttggaggtaa ttacataaaa
    19261 acaaaaaaaa tatagcaact ctctataaga aagttgctat attgataatt ataccggcgg
    19321 ccggggtcga accggcacgt cctcaacgga cactggattt tgagtccagc gcgtctgcca
    19381 attccgccac gccggcaaat ttaaaaataa taactggggt agctggattc gaaccaacgc
    19441 atgagggagt caaagtccct tgccttaccg cttggctata ccccaagaat aaagggcgaa
    19501 tgatgggaat cgaacccacg aatgccggag ccacaatccg gtgcgttaac cacttcgcca
    19561 cattcgccat cataaaagat gttatttaat ttctcaataa aaaactaaga tgaagacatc
    19621 ttagtcaata ccggcggccg gggtcgaacc ggcacgccct caacgggcac tggattttga
    19681 gtccagcgcg tctgccaatt ccgccacgcc ggcaagttga tttattagta ctaaggcggt
    19741 aaccggattt gaaccggtga tgaaggtttt gcagacctct gccttaccac ttggctatac
    19801 cgccattata ctattatcaa tctataaaat aaagaataaa ttatagaaac tggggtagct
    19861 ggattcgaac caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc
    19921 aagaataaaa agggcgaatg atgggaatcg aacccacgaa tgccggagcc acaatccggt
    19981 gcgttaacca cttcgccaca ttcgccatgg caggggcagc aggaattgaa cccacactaa
    20041 cggttttgga gaccgctgtt ctacctttaa actatgcccc tataaaatgg aggagagtgg
    20101 attcgaacca ctgaacccta aggaacggat ttacagtccg tcgcgtttag ccacttcgct
    20161 actcctccat ggtggcgcgg gacagaatcg aactgccgac acacggagct tcaatccgtt
    20221 gctctaccaa ctgagctacc gcgccatatt ttaaaattat taattgaata acaagaacga
    20281 cggttccgac gggaatcgaa cccgcgatct cctgcgtgac aggcaggcat gttaacccct
    20341 acaccacgga accagttcat tatggaggtt aacgggatcg aaccgctgac cctctgcttg
    20401 taaggcagat gctctcccag ctgagctaaa cctccaacat tcaattaaaa tgacccgtac
    20461 gggattcgaa cccgtgttac cgccgtgaaa gggcggtgtc ttaaccgctt gaccaacggg
    20521 ccaggtaaat ttgctacgga gagtaaggga ttcgaaccct tgagacagtt tggcaccatc
    20581 tacatgattt ccaatcatgc tccttcggcc tctcggacaa ctctccagag tgaaagaagc
    20641 tcaatactct ttctcaaaat gagaactccg gcagtaggac tcgaacctac gacatcatga
    20701 ttaacagtca tgcgctacta ccaactgagc tatgccggaa taacatcagc gtggcgacgt
    20761 cctactctca caaggggcaa cccctcacta caatcggcgc taagaagctt aacttctgtg
    20821 ttcggcatgg ttacaggtgt atccttctcg ctatcgccac cacactgtgg tgttatcttt
    20881 tattgagtaa attttgttca ctcaaaactg gatttgaagt cacataagtt tttttccgag
    20941 t
//
LOCUS       DASHWW010000046        20782 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.046, whole genome shotgun sequence.
ACCESSION   DASHWW010000046 DASHWW010000000
VERSION     DASHWW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.046"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(18..1574)
                     /gene="rny"
                     /locus_tag="U2R64_001880"
     CDS             complement(18..1574)
                     /gene="rny"
                     /locus_tag="U2R64_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEM8918681.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1985..3034)
                     /gene="recA"
                     /locus_tag="U2R64_001881"
     CDS             complement(1985..3034)
                     /gene="recA"
                     /locus_tag="U2R64_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEM8918682.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3143..4384)
                     /locus_tag="U2R64_001882"
     CDS             complement(3143..4384)
                     /locus_tag="U2R64_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEM8918683.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4624..5202)
                     /gene="pgsA"
                     /locus_tag="U2R64_001883"
     CDS             complement(4624..5202)
                     /gene="pgsA"
                     /locus_tag="U2R64_001883"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEM8918684.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5411..6334)
                     /locus_tag="U2R64_001884"
     CDS             complement(5411..6334)
                     /locus_tag="U2R64_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918685.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(7073..8359)
                     /locus_tag="U2R64_001885"
     CDS             complement(7073..8359)
                     /locus_tag="U2R64_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEM8918686.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8352..9620)
                     /locus_tag="U2R64_001886"
     CDS             complement(8352..9620)
                     /locus_tag="U2R64_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEM8918687.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9872..10333
                     /gene="mscL"
                     /locus_tag="U2R64_001887"
     CDS             9872..10333
                     /gene="mscL"
                     /locus_tag="U2R64_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEM8918688.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10392..10838)
                     /locus_tag="U2R64_001888"
     CDS             complement(10392..10838)
                     /locus_tag="U2R64_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8918689.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10931..11176)
                     /locus_tag="U2R64_001889"
     CDS             complement(10931..11176)
                     /locus_tag="U2R64_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEM8918690.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11290..11868)
                     /locus_tag="U2R64_001890"
     CDS             complement(11290..11868)
                     /locus_tag="U2R64_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8918691.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11945..12475)
                     /locus_tag="U2R64_001891"
     CDS             complement(11945..12475)
                     /locus_tag="U2R64_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEM8918692.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12479..13339)
                     /gene="rlmB"
                     /locus_tag="U2R64_001892"
     CDS             complement(12479..13339)
                     /gene="rlmB"
                     /locus_tag="U2R64_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEM8918693.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13332..13727)
                     /locus_tag="U2R64_001893"
     CDS             complement(13332..13727)
                     /locus_tag="U2R64_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEM8918694.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13724..15136)
                     /locus_tag="U2R64_001894"
     CDS             complement(13724..15136)
                     /locus_tag="U2R64_001894"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEM8918695.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15133..15669)
                     /gene="cysE"
                     /locus_tag="U2R64_001895"
     CDS             complement(15133..15669)
                     /gene="cysE"
                     /locus_tag="U2R64_001895"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEM8918696.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(15755..15994)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15991..17451)
                     /locus_tag="U2R64_001896"
     CDS             complement(15991..17451)
                     /locus_tag="U2R64_001896"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEM8918697.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17621..18778)
                     /locus_tag="U2R64_001897"
     CDS             complement(17621..18778)
                     /locus_tag="U2R64_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HEM8918698.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18812..20182)
                     /gene="radA"
                     /locus_tag="U2R64_001898"
     CDS             complement(18812..20182)
                     /gene="radA"
                     /locus_tag="U2R64_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEM8918699.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20245..20772)
                     /locus_tag="U2R64_001899"
     CDS             complement(20245..20772)
                     /locus_tag="U2R64_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEM8918700.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5473 a         4592 c         3706 g         7011 t
ORIGIN      
        1 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
       61 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
      121 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
      181 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
      241 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
      301 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
      361 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
      421 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
      481 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
      541 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
      601 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
      661 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
      721 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
      781 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
      841 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
      901 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
      961 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
     1021 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
     1081 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
     1141 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
     1201 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
     1261 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
     1321 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
     1381 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
     1441 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
     1501 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
     1561 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
     1621 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
     1681 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
     1741 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
     1801 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
     1861 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
     1921 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
     1981 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
     2041 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
     2101 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
     2161 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
     2221 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
     2281 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
     2341 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
     2401 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
     2461 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
     2521 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
     2581 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
     2641 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
     2701 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
     2761 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
     2821 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
     2881 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
     2941 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
     3001 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
     3061 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
     3121 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
     3181 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
     3241 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
     3301 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
     3361 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
     3421 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
     3481 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
     3541 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
     3601 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
     3661 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
     3721 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
     3781 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
     3841 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
     3901 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
     3961 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
     4021 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
     4081 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
     4141 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
     4201 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
     4261 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
     4321 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
     4381 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
     4441 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
     4501 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
     4561 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
     4621 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
     4681 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
     4741 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
     4801 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
     4861 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
     4921 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
     4981 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
     5041 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
     5101 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
     5161 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
     5221 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
     5281 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
     5341 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
     5401 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
     5461 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
     5521 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
     5581 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
     5641 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
     5701 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
     5761 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
     5821 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
     5881 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
     5941 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
     6001 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
     6061 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
     6121 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
     6181 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
     6241 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
     6301 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
     6361 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
     6421 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
     6481 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
     6541 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
     6601 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
     6661 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
     6721 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
     6781 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
     6841 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
     6901 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
     6961 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
     7021 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
     7081 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
     7141 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
     7201 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
     7261 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
     7321 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
     7381 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
     7441 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
     7501 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
     7561 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
     7621 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
     7681 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
     7741 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
     7801 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
     7861 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
     7921 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
     7981 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
     8041 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
     8101 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
     8161 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
     8221 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
     8281 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
     8341 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
     8401 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
     8461 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
     8521 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
     8581 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
     8641 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
     8701 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
     8761 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
     8821 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
     8881 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
     8941 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
     9001 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
     9061 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
     9121 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
     9181 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
     9241 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
     9301 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
     9361 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
     9421 agctctgcaa gttgcgcact taactttgtc tgatccggat aattcaaact atttgtttcc
     9481 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
     9541 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
     9601 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
     9661 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
     9721 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
     9781 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
     9841 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
     9901 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
     9961 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    10021 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    10081 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    10141 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    10201 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    10261 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    10321 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    10381 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    10441 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    10501 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    10561 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    10621 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    10681 gtatcttgaa aaaacgtatg ccaagcttgt ccatcaatgt catcaacttc ttgataagga
    10741 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    10801 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    10861 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    10921 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    10981 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    11041 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    11101 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    11161 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    11221 ttcaagttta ccataaaaaa aaagaaatgc aataaaaata aataagaagc tcattaagat
    11281 ttttctaaat tattcctcat tataaaattt caagtgtttt tttattttga gttttactct
    11341 cccgtaagcg ctcattactt gcttgtgatc cattgctaaa cattcagcca tgtctacaaa
    11401 atcaacgcct tgcatataat aatgaaaaat tttagcttct atttttgaaa actggatttc
    11461 gcaattttcg attgcttctt ttaataaaag atgctgaatc gctaaaggtt cttgcaatgt
    11521 gatctctgct aaaaagtctg gtccttctgt ctctattttt tggtcgattg agacttcatc
    11581 tttttgatca cgacgcttca gcgcgttctg cttcctcaac agagaataga tttgattgct
    11641 tataatgctt ttataataac ttccaaagct aacacctttg cttttttcgt aagttctcaa
    11701 tgcctgatat aaagcgatcc ttgcttcttg ttcccaatcc tcagaaacat aatttcttaa
    11761 ataataggtg tttttcaaac gtagtaaaag tggaaaatat ttttgataca gggcagcaaa
    11821 tgcttcttcg tcaccattac gtgcagcgcg caataactcc tcagacataa aataattcct
    11881 ccataaattc gtttatggag gaatcttatc atcaatgatt catcgaactg attagaacga
    11941 tatgttattt attttttctc attaaatcgt ccaatttttg ggacaatttt tttaactgct
    12001 cttcattcca tggagaatta cgtcggaaat caataaaatg catatcttta ttttcttggg
    12061 ctattgtttt ttccgttttt tttatcgtct tatataattc ataagcagaa gttcgtaatg
    12121 ctccttggga aaagatcatc cactgttctg ctaaatcgct tgtcgccact gtcacttgtg
    12181 tcaaacggtc attcagctga ccagcgattc tctcgatata actgtcagcc gtttcgtctt
    12241 ctttcgtaaa aacaacatcc aactggtatt tcttataatt ttgttggatg cccggaacta
    12301 gttgggcatc gaagacaacg atgacttcca ttccttcata tttcgcataa tttgataaac
    12361 gatgtaaaag agcttctctt gcatccgcca ttttgtcctg ctttttaagc tggacaagtt
    12421 ccggccacga accaatcatg ttgtagccgt ctacaatcaa cagctgtttt ttcatggtct
    12481 actccccctg acgttgggaa aaagcctgat acataagcaa accagcagca acactggcat
    12541 ttaagctctg gacgtgcccg gtcatcggga tcgtcagcaa ttcatccatt tcttttttca
    12601 atcctggact cattcctttg ccttcattac caatgactaa agcaattgat cctttggcat
    12661 tccatttttg gaagtttgtg ccggtcatat ctgtgccaaa tacccaaaat cctgtttctt
    12721 tgagctgttg cacagcttgt accaaattcg tcacgcgtgc aacagggaca tgttcgactg
    12781 ccccagtgga agtctttgtt acgataggtg tgattccaac tgctcggtgt tttggtatga
    12841 tcacaccatc gacgccactt gcgtctgctg tccgtaaaat cgacccaaaa ttgtgtggat
    12901 cttcgatgct atccaaaatc aaaaagaagg ggtcttcttt tttctctttt gttcgttcaa
    12961 tcagttggtc aagggataaa tattcataag gtgtaatcgc aagaacgact ccttgatgca
    13021 cgccgtgatc gctcaaagtt tctaattttt gtttaggaac ccatttgact ggcacagctt
    13081 gttcacgtgc gatttctttc agttcttcta ctttttctcc tcgtgaatct tcttgaagaa
    13141 agagtttatt ccctcgccct tgttgtagcg cttctactgc ggcatggtgc ccaaagacga
    13201 aattatcttc taatgcttct tcattttgat cagaaactga ctgatttcgt ccagtttgct
    13261 ttttatttga atatctattt tgttttttgt cttcaaatcc acgtttcgat tgatgtttgt
    13321 ttgttctttc tttacccatt tttttcacca actttctgaa tacaccagcg gatcaattct
    13381 tccatccgct cggtttgttt tgtcaaatgc agatagccca tgagcgcttc gaaccctgtt
    13441 gcgacccgat acgtcgtaac atcagcattt tttgcgctcg tatggctttt agcatttctt
    13501 cctctgcgat aataaagttc ttcttcttct gtcaaaagat gttcttccag catttgctga
    13561 atcaaaaagg cttgtgcatt cgcagaaaca taattcgttg ccgcacgatg cagcttattg
    13621 ggttttgttt ctccttgatc aatcaggtgg tcacgaacat agatttcgta aatcgcatct
    13681 ccaacataag ccaaggctaa accgttcaat tgtgtgtaat ctctcatgct tctcttctcc
    13741 atcgggttcc ttgcggtgta tcttctaata agatcccttt ttctttcaac aaatcacgaa
    13801 tttcgtcgct tcggacaaaa tcacgattgc ttcttgcttg atttcgttct tcgatcaatt
    13861 gttcaatctc ttcatctaat aactcttctg ctgtaaataa aataccgaag atcgaaagcc
    13921 attgcgagaa taaagcttct ccttgtgcca agacagcggc agaaactttc ggctggtcta
    13981 gataagtgtt cagccactta gcaagctcat agaccactgt gatcccattt gctgcattaa
    14041 aatcatcgtc catttcttcg atgaatcgct gttctaaatt ttctaacaaa gcgattttat
    14101 ccgcatcatc tgccaaattc tctgaggcag tttcttggcg gaatttcaaa ttgtcaaacg
    14161 tattcttcag tcgttgtaaa ttggtggctg cttctttcat cgtcgtttca ctgtagcgga
    14221 tcggacgacg gtattgtgtg gtcgccatga agaaacgcaa gacttgtgga tcaacgtttt
    14281 tgatcatttc atgtacagtg atgaaattcc ctagagattt actcattttt tcatcgtctt
    14341 cgccaatcgt tacatagcca ttgtgcatcc agtaattagc gaattttttc cctgttttcg
    14401 cttcactttg tgcgatttca ttttcatgat gaggaaattc taaatcttgc ccgccaccat
    14461 ggatatcgat cgtttctcct aaatgttttg ttgccataac ggaacattca atatgccaac
    14521 cgggacgtcc tttgccccat ggtgaatccc aagaaatctc gccaggtttt gcttgtttcc
    14581 ataaagcgaa atctaatggg tcttcttttt gctgctgttc ttcccctgta cgctgacttg
    14641 ctccgacttc cagttcatcg atggattggt cacttaattt cccataattt tcaaatttac
    14701 gggtacggta atacacatca cctgaagatt cataagcata gcctttttca accaacactt
    14761 gaataaatgc taaaatatct ggcatatgat ccatgactct tggatgcagt gtagcaggct
    14821 cgacattcaa cgctttcgta tcttcttcaa atgctcggat gaaacgatca gcaacttctg
    14881 gtgctgtaat acctaattcg tttgctgtac ggatgatttt atcgtctaca tccgtgaaat
    14941 tcgatacgaa atcgacttta tagcctcgat attcaaaata gcgtcgaatt gtatcgaaag
    15001 caatggtgct acgagcattt ccgatatgga tataattata cacagtcggt ccgcagacat
    15061 acataccgac atgtcccttt tgtataggga tgaattcttc tttttttctg gtcaatgtat
    15121 tgtagatttt tatcattctg atctcctcac tttttctcct ttgattcgaa cgacttttgc
    15181 tggtactcct accgctgtag cgtcgtctgg aacatctttc aacacaacgg cacctgcacc
    15241 gattttggcg ttttttccga tcgttaccgg tcctaatatc tgcgcattcg cagagagcat
    15301 ggctccttgt ttaacagttg ggtgtctttt acccgtttct tttcctgtgc cgcctaatgt
    15361 tacgccatgg aataaaatca catcgtcctc gatttctgcg gtttcgccaa tgacgattcc
    15421 cattccatgg tcgatgaaca cgccagttcc aatcgttgct cctggatgga tctcaacacc
    15481 agttaggaaa cgccagaatt gagcattgat cttcgccaat aaaaagagcc ggtgctgata
    15541 taaaaaatga gagaaacgat gccaaaacaa ggcatgaaaa ccagggtatg tcaaaacgat
    15601 ctcagctgtc gaacgtgcag ccggatcgtt tctctttgct gcatcaatcg ctcgggtaaa
    15661 ccaactcatg actttccact cctttcgtaa gaattttatg taggaaatca tcttcttata
    15721 aagaaaagaa gcgcctttta aataagtttc cttatcaaaa gacgctttcc gcgtggttcc
    15781 acttttcttc ataatcaatg attatctctg acagctaacg cctgttatac gttcttggct
    15841 actttgtttc ctataaaaca gtttttcctg ttttctgtgt ttcgccaaga ccactcccag
    15901 aggcatttcg gcaaccattc attgatacct tgcaccaccc ggtatctctc ttgtaatgat
    15961 cagctgctta cttttttctg ttcatcgtgt ttagttcagt acttgattta aatgtgctaa
    16021 tgatttttca cgaccaagca attcgatcgt ttcaggcaat tctggaccat gcatttgtcc
    16081 tgatacagct acacggattg gcatgaaaag attttttcct tttacgccag tttctttttg
    16141 aacagctttg atggcagctt tgacagttgg agcatctact acttccattt gttctagctg
    16201 tgctttgaat gcgtggagaa cagtaggaac tgtttcacca gcaagtactt cttttgctgc
    16261 ttcattcaat acaggatgtt cattgaaaaa tagcgtagac agatcaacga tttctgcagc
    16321 atagctcatt tgaggttgat acaggctaac gatcttcttc acccattcga ttgtcttttc
    16381 atctgggttt tctgctacac gtccatcagc gattagataa ggcagacaca tgtcagtaaa
    16441 tgcatctaga tccattgctt tgatgtaatg gttgtttacc cattgcagtt ttttcgcatc
    16501 gaaagctgcg ggtgatttac ttaggcgttt tggatcgaac attttgatca attcttggtg
    16561 ttcgaagatt tcgtcttcgc ccacaggtga ccagcccaat aatgcaataa agttgaacat
    16621 tgcatctggt agatagccta attcgcgata ttgttcgata aattgcaaga ttgattcgtc
    16681 acgtttgctt agttttttac ctgtttcact gttgatgatc aatgtcatat gtccgaaggt
    16741 tggtggtgtc cagccaaatg cttcatagat catcagttgt tttggtgtat tggcaatatg
    16801 gtcatctcca cgtaaaacgt gagtgatttt catcaaatga tcatcgaccg caacagcaaa
    16861 attataagtt ggcataccat cgcgtttttg tatgacaaag tcgccaccga tattatcgga
    16921 ttcgaacgaa atagcgcctt tcaccatatc tgtaaatgcg tattctgtat tgcgaggcac
    16981 acggaaacgt acaacagatt ctagaccttg tgcttctttt tctgcttgtt cttcaggtgt
    17041 caagttcgca catgttcctg cgtaatgagg catttctcct cttgcgcgtt gtgcttcccg
    17101 ttctgcttct aattcttctt ctgtgcaata gcatttgtat gctcgattgc tagcaagcag
    17161 ctgatcaatc agcggttgat agatttcttt acgttcagat tgacggtaag ggccgtattc
    17221 tccaggattt tcaggagatt catcccaatt cattcccaac caagcaaggt tttccaactg
    17281 gcttttttcg ccatcttcga tattacgttt ttggtcagta tcctcaatac gaataataaa
    17341 gtctccatca ttgtggcggg caaacaaata attgaataat gcagttcttg catttccaat
    17401 atgcaggtgc ccagttggac ttggtgcata gcgtacgcgt actttcgtca ttttcttcct
    17461 cttctttcaa actagacttt gactaacagc aaaaattccg tcagttacgg cttctcaaat
    17521 atcatttatt taaagccact cagcacaaat tttacctttt ctaaggtaaa tagtaaagcc
    17581 aactggttga atttccttac cagttggctg aatttctttt ttattttgat tgtttagtct
    17641 ttttctctgt ctctttttta ttgtcgattc ctcgtcctgc atgtgcaggt ttagcaaaga
    17701 tcatgcgtcc agcagctgtt tgaagggcac ttgttacaac gacttcgata cgttcattca
    17761 tgtaatgctg tccatcttct acgacaacca tcgtgccgtc atcaaggtag gctactcctt
    17821 gttggcgttc tgtcccggct tttactacta gaacattcat cgtttcacca gggatgacga
    17881 ctggttttac ggcatttgcc aacgcattga tattaagaac aggtacattt tggaattcag
    17941 agactttatt caagttatag tcattggtta caatgacacc atctaaaagc ttagccaatt
    18001 tgatcaattt gctgtctact tcactgatat cttcaaagtc tccatcgtac atttcgacag
    18061 atataccctc ttctttttgc aaggcattta ggatatctaa tccgcgacga ccacgcacac
    18121 gtttcaaact atcccctgag tccgcgatgt attgtagttc gtaaagaaca aaattaggga
    18181 tcatcaaggt tccttctaag aatccagtct ttgtaatatc ataaatccga ccgtcaatga
    18241 tcacgcttgt atccaagatt ttatatttat ggaaattttc tcctgatttt cgttctaaca
    18301 gttgactctc aacttgacta gctgtttctt gctcgatttt tttgcttcgt gaaccaaaaa
    18361 ctttcttcca ttcttcgatt cgtgtcgttc ccattctcaa tcccagatag cctaagatga
    18421 tcatcagtaa aatcggcaat acactattga cgaatggaat ttccatattg taaagagggg
    18481 tcgagatcac aacacctaaa gtcaatccga tgatcgcacc gatcgcaccg aagagaagat
    18541 aagtcaagct gacctcactt agtttttgtt ctacttgttt gataatagct gagatatgtt
    18601 tggccaacag caaagataat aaaaagaaaa taagtgcgcc taacaggctg ttggtaaatg
    18661 tattattcag ccatccgttt gactgttgac cgattgcctg ccaagctgag ggtaaaaatg
    18721 aaatacccaa gcttgcgccg acaatgatca tcagcaaagt aatgacacgt ttttgcatcg
    18781 tttttcctcc gtttcgacaa tcatttatta gttagcggaa cacacgcttc aacgtttcag
    18841 ccaaagttgc tactccaact atctcgattc cttttggcgc ttcccagtta cctaagttgt
    18901 ttttaggtag gtatactttt gtgaagccga gtttttggac ttctttgact cgttgttcaa
    18961 tatgactgac acgtctgatt tctccagtca gtccaatttc accgatgaaa cattccgttg
    19021 gctgtgttcc tttttcttta tagcttgaag caatactgac agcgatagct aaatcaatcg
    19081 ctggttcatt taattttacc ccacctgcag cttttaagta agcatcttga ttctgaagaa
    19141 gcaacccagc tcttttttcc agcactgcca tgatcagaga tacccgattg aaatcaagac
    19201 ctgttgttgt tcgtttggca tttccgaaca tagtaggtgt gactaatgct tggatctcta
    19261 ccaaaattgg acgtgtccct tccattgcca caacgatagc agagccagtt gcaccgtcta
    19321 ggcgttcttc taagaaaatc tgtgaaggat tagcgacttc ttccaatcca tgctcatgca
    19381 tttcaaaaat cccaatctca ttcgttgagc caaatcggtt ttttactgct cgcaaaatcc
    19441 gaaaactatg atgttgttca ccttcaaaat ataacaccgt atccaccata tgttctaaca
    19501 ttcttgggcc ggcgatcgag ccttctttgg taacatgacc gacgataaaa atggctatcc
    19561 catttgtttt agcgattttg agtagttctg cagtggtttc tcttacttgg ctgacacttc
    19621 ctgccacact tgtgatgtct ggctgcgtca tcgtttggat ggaatcaatg ataacataat
    19681 caggggagat atgttcgatg gcacgactga tttcgttcat atctgtttca gcgtatagat
    19741 aaaattctgt gttgatactt ccgaggcgtt ccgcgcgtaa ttttatctgc tctgcgcttt
    19801 cttcgccgga tacatataag acttttccgc ctatggctgc taattgctga gaaacttgta
    19861 acagcaaagt ggatttcccg atacctggat cgccaccaat caagaccata gaccctggca
    19921 ccacacctcc gcctaacaca cggttcagtt cttctaattt tgttttgatc cgaggttctt
    19981 ttttagggac gacgtctgcg atttttgttg gttttgcttt ttctcctgtc aaacttgtcc
    20041 gagttctgcg gtccgttgta tcttgttcga tttcttcgac catcgtattc cattttccgc
    20101 aatttgggca gcgtcccaag aacttaggcg acacataccc gcaattttgg caaacaaatt
    20161 gtacttttga tttttttgcc attgtaccgc ctccttttat cctaatcatg agacattaaa
    20221 tcaagcttaa gtatctttaa cgttttattt actggaagaa ccaaatccgc cttgacgttg
    20281 agcagtcgtt tgatcttgat ctgcttttaa aaacggcaaa aagatccctt ggccgatacg
    20341 ctcgcctttt ttgatcacta catccttgaa accaaagttg gtgaattgga acatgatatg
    20401 gccttcattt gcctcattat tgtaataatc actgtcaatc acacctactc cgtttgtcaa
    20461 cactaaaaac cgcttcaacg gattgcttga acggttagca agctgcaaaa attcatcttc
    20521 tcccatgtaa gctttgattc cagtaggcac gagggttggt ttcaattgtt tttcattttc
    20581 tgatacatct tttttcaatc catctgcgac tgtttccaac ccctttttcc agcctgcttt
    20641 ccagatactt ggaatcacga cctcttctgc tgcttcaaaa tcatagccag cagcatgatg
    20701 tgtagcgcgc tgcggtagat tgatattttg atctttatat ttagaaataa cttcaaatcc
    20761 tctttttctc accggttttc ct
//
LOCUS       DASHWW010000047        20415 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.047, whole genome shotgun sequence.
ACCESSION   DASHWW010000047 DASHWW010000000
VERSION     DASHWW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.047"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1835)
                     /locus_tag="U2R64_001900"
     CDS             complement(<1..1835)
                     /locus_tag="U2R64_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918701.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
     gene            complement(1832..2536)
                     /locus_tag="U2R64_001901"
     CDS             complement(1832..2536)
                     /locus_tag="U2R64_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918702.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2548..4857)
                     /locus_tag="U2R64_001902"
     CDS             complement(2548..4857)
                     /locus_tag="U2R64_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEM8918703.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5052..5516)
                     /locus_tag="U2R64_001903"
     CDS             complement(5052..5516)
                     /locus_tag="U2R64_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918704.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5516..6142)
                     /locus_tag="U2R64_001904"
     CDS             complement(5516..6142)
                     /locus_tag="U2R64_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8918705.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6149..6514)
                     /locus_tag="U2R64_001905"
     CDS             complement(6149..6514)
                     /locus_tag="U2R64_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEM8918706.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6504..6842)
                     /locus_tag="U2R64_001906"
     CDS             complement(6504..6842)
                     /locus_tag="U2R64_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918707.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(6832..7158)
                     /locus_tag="U2R64_001907"
     CDS             complement(6832..7158)
                     /locus_tag="U2R64_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEM8918708.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7136..7417)
                     /locus_tag="U2R64_001908"
     CDS             complement(7136..7417)
                     /locus_tag="U2R64_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEM8918709.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            complement(7419..8783)
                     /locus_tag="U2R64_001909"
     CDS             complement(7419..8783)
                     /locus_tag="U2R64_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEM8918710.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(8796..9365)
                     /locus_tag="U2R64_001910"
     CDS             complement(8796..9365)
                     /locus_tag="U2R64_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEM8918711.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9337..10524)
                     /locus_tag="U2R64_001911"
     CDS             complement(9337..10524)
                     /locus_tag="U2R64_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8918712.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10588..12315)
                     /locus_tag="U2R64_001912"
     CDS             complement(10588..12315)
                     /locus_tag="U2R64_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEM8918713.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12312..12764)
                     /locus_tag="U2R64_001913"
     CDS             complement(12312..12764)
                     /locus_tag="U2R64_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEM8918714.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(12876..13256)
                     /locus_tag="U2R64_001914"
     CDS             complement(12876..13256)
                     /locus_tag="U2R64_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEM8918715.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13253..13639)
                     /locus_tag="U2R64_001915"
     CDS             complement(13253..13639)
                     /locus_tag="U2R64_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918716.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13641..13919)
                     /locus_tag="U2R64_001916"
     CDS             complement(13641..13919)
                     /locus_tag="U2R64_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918717.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            13967..14695
                     /locus_tag="U2R64_001917"
     CDS             13967..14695
                     /locus_tag="U2R64_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEM8918718.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(14841..15317)
                     /locus_tag="U2R64_001918"
     CDS             complement(14841..15317)
                     /locus_tag="U2R64_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEM8918719.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15277..15624)
                     /locus_tag="U2R64_001919"
     CDS             complement(15277..15624)
                     /locus_tag="U2R64_001919"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918720.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15611..15796)
                     /locus_tag="U2R64_001920"
     CDS             complement(15611..15796)
                     /locus_tag="U2R64_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918721.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(15797..16069)
                     /locus_tag="U2R64_001921"
     CDS             complement(15797..16069)
                     /locus_tag="U2R64_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HEM8918722.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16066..16269)
                     /locus_tag="U2R64_001922"
     CDS             complement(16066..16269)
                     /locus_tag="U2R64_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918723.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16394..16606
                     /locus_tag="U2R64_001923"
     CDS             16394..16606
                     /locus_tag="U2R64_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918724.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16639..16833)
                     /locus_tag="U2R64_001924"
     CDS             complement(16639..16833)
                     /locus_tag="U2R64_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918725.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(16841..17029)
                     /locus_tag="U2R64_001925"
     CDS             complement(16841..17029)
                     /locus_tag="U2R64_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918726.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            complement(17026..17166)
                     /locus_tag="U2R64_001926"
     CDS             complement(17026..17166)
                     /locus_tag="U2R64_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918727.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(17656..18021)
                     /locus_tag="U2R64_001927"
     CDS             complement(17656..18021)
                     /locus_tag="U2R64_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918728.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18061..18363)
                     /locus_tag="U2R64_001928"
     CDS             complement(18061..18363)
                     /locus_tag="U2R64_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEM8918729.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18363..18662)
                     /locus_tag="U2R64_001929"
     CDS             complement(18363..18662)
                     /locus_tag="U2R64_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918730.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18655..18819)
                     /locus_tag="U2R64_001930"
     CDS             complement(18655..18819)
                     /locus_tag="U2R64_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918731.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(18825..19094)
                     /locus_tag="U2R64_001931"
     CDS             complement(18825..19094)
                     /locus_tag="U2R64_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918732.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19106..19855)
                     /locus_tag="U2R64_001932"
     CDS             complement(19106..19855)
                     /locus_tag="U2R64_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918733.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(19858..>20415)
                     /locus_tag="U2R64_001933"
     CDS             complement(19858..>20415)
                     /locus_tag="U2R64_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918734.1"
                     /translation="DRVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFF
                     YFRFEGVTGRKISLKDESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYF
                     YKCITKRVCCICGKTGADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVI
                     NFKNKYQIKGIKLNQKTIKKLNIGG"
BASE COUNT         5662 a         4317 c         3184 g         7252 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcat caggataccc accaggtgtt
       61 tctcctccgc cagatggacc gccattttgt cctggtatca cttctttacc tctaacagta
      121 agttttccct gaatatctaa atcaccgaaa taatatgctt ttccgtttcc taataacaca
      181 aatccttttt ctgcagttgg agaaattaaa atgtattttc catcgccatt tgtacgtatt
      241 accaaagaat tttcctcaag aggtgtaggt gttacagcat ttggaaatgg atttcctgct
      301 gaatctgttg ttccgatcgt tccaatggat tcttttctat tccagaattc catacctttt
      361 ttggttagct ccatgatttt tttgttttca ttccaaattt gaagcgtgcc ttttacaagt
      421 tttaacacat caccataagc attaaaggaa gtttcgaata cttctgcatt tattgttcct
      481 actttgatga agtcagcaac aatttctcct tttgatgtga tagcaatacc gaacgggcca
      541 tttactccgt tgtctgaata acctaagcca tttaaattcc aacgccacac tcgctttgca
      601 ttcgccacat ttggagtatc catgataaga atctctgatg gagctttttc tggacgaaaa
      661 acgacatgcc caccagaatt accagtgatc catgccgtcg cattcaacac attttgaact
      721 aacgtttctg ttcgattgtc gattttcttt ttcaattctt gtgcttgagt atttactgcc
      781 gaagtgtaca gtgataaatc attacctaaa acaatatcct tatatttccc aagcgttggg
      841 aaataagtgt attcgaccat acgctctttt atctcgatat ctagctcttt cgccctaaca
      901 tgagcgacat caccaaagtg taaagacgct agctcttgat acatgtcacc gtattcgagt
      961 gtgtgttcca acgccaccat actgactgta tgagtagctt ttggctcatg gatacgatca
     1021 ttgtcaaata aggttttgcc ccatttgatc aattcatcaa ctgttttaca atctccgttt
     1081 tcacgtttgg caatacgtcg attctcgttg gttactccat caatttctaa ataaccatat
     1141 tcgataggtt ctttgtcttc atcataatcg ttatcaggaa caccgccaac caaatacaaa
     1201 ctattgacaa ttgattcttc atcaatttct tcttcgattg cttctaaatt gatgccaaaa
     1261 tcaatccgaa aaccattatc tgatccaatc tgttttacca gtttcaaatc atagttatcc
     1321 atatcaagtt ccgcgctagt cacgccagtc aaattttgat taccgttatt tgaaccaatg
     1381 attgcttcaa ctggcgcgac ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa
     1441 agatagttaa atttttgatc aaatgccaaa ctgtttttaa gattggtcat gatctgagac
     1501 ccattgccgt tatccgtaaa cgacttgaca ataaagttct tattggccat aaaaccaata
     1561 tgccgagctg ttacagaaac ggaggtcaaa ttctttttga cattataaat ttcaaaatat
     1621 tgccatgatc catctggtac cttcgctttt ataaaatttc ctttttttaa ataagagcga
     1681 tactgtccgc ttcttgaata gttaccataa aaacgatatt ggccattcag cacacgattg
     1741 atttctggca aatcttccca atcaactaac gacgctccgt tcacgctcaa atcatctggc
     1801 atttttttat aagcataaat aaattcttgc gtcacagata cacactccta ttccaaaacc
     1861 gcacttcttt aaattttccg gatattttta cctgattcca ttcaggctgc aatactggcc
     1921 aatcaccacg cgtaaataaa ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa
     1981 ccacgattgt tgcagctaac gtattaagta ttgttaggct tttatcaccg acagcgatcg
     2041 ttatatctcc tccgttcgat tctatttcca gatagggatg tgcaatttcg tcaccatgat
     2101 caaaaatatc cataacacta gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga
     2161 gtggctgaca acgaaaagta acatcgaatg tataaaagaa gccccactcg ttttcgaaag
     2221 ggacttcttt atccatgctg cagatagcct ctagatactt gtctggatca ttatgtgtga
     2281 ttaattggct tttaccagtg agccatcgtt tgacttctct cagtttcgaa tgtggaatag
     2341 tgatcccttc tatttccaaa tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc
     2401 cgcttcggcc ctgaatcgtg taagtttcgt atcgcttgtt cggcataata tctggaagct
     2461 ctgcctcaat gatgcaattc atatcaatta ctgcattccg atttttccaa ataaaatttg
     2521 gttcatctgg attcataaat tgtcgactca aataggaaca cctcccaaat cacgaatagc
     2581 ctgtttgttt gctttagcaa atttacgatt catacgatct aactcagatg gattgtttgc
     2641 atcgactttg ccaatgtgta tatgctgttc aatgctacct ccagaaactc ttccactgat
     2701 ccctttgcgt ttttcttcgt ctgataatgg agtaactgtg gttttaccat tcttggcagt
     2761 cagtaactca ggtccagctt caccaacaat cgcttgtcca ttgattagat gaccgccttg
     2821 tgctaaataa ggcagttttg aaatagaaaa tgattttcca cctacaccag gaacccattt
     2881 tggtatcttt atattattca atccaccaat aaatccattg atcaatccaa tcatggcatt
     2941 aataggagct ttccctacag caacaatacc atcgaaaata cctccaaaaa tatcaactag
     3001 accttgccat gcttttgacc aattccctgt aaatactcca gtgataaaat ctagaaaacc
     3061 actgaaaatt cgttttccag cattataaaa attattgaaa tttgctataa caccatcgaa
     3121 aaatccacca aaataaccac ttaaaaaatt aaatatttca acagctacat ctgaaacacc
     3181 tttgaagaaa gaattcactc catcatgaaa ccatttaacg ttattatatg cccaaattag
     3241 tccagtaact aatgcgccaa tagctataac tgctaatgca aaccagcctc ccgacattcc
     3301 aaataaacca gcaagtcctt gccaaactcc tataaaactt ttaacttccc caacgatttt
     3361 tgtaacagat cccataagtg aaccaagaac gattagtact ggtccaactg ctgccgctat
     3421 accagcaatt gttatgatcc aattctttgt atcttgatct agagaccccc accatttaga
     3481 gaattcctgt aataaggaag ttgctttttc aaaaaaaggc aaaaggctta cttggactgc
     3541 ttcacctacg tcagccattg ctaattttgc attgttcata gcttgatcgg cttgatcaat
     3601 tgggtcgaga gtagcatcga atgtgtctcc tacagctccc ccactttctc cagcagtttt
     3661 tgctaaatct tccaggttca aagtacctct acgaattgca tcggccattc taggaccgcc
     3721 tttagtcccg aatacttctg ctgctgcatt gatggcttct gtttcagaac ctgcattttt
     3781 taccttgtct tgtagttctt ctagtccttg acttaaagat tttccgtctt tcgcataagc
     3841 cactgttgct ttagataaac tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa
     3901 ttgtccaagt aaagtgaccc cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc
     3961 gccatcaatt gctttttgca tcaagtcgtc tacagattga ccagtattct gcgatgtttt
     4021 cgttgttaca tcaaggacag aattcaaatc atcatattct agtccataag catcaatagc
     4081 ttgtcgagca gatattgctg attgcgaaac atctgtatca ttgatttcag cgtactgtag
     4141 gagataattg gttgaatctt ccagtttttt atccatgaat ccaaattgtg tatttacctc
     4201 accaatagct tccccaaccg tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa
     4261 agactgtgaa agtctatcag cttgatcacc tgttgctccg gtttttgtaa tgatggtatc
     4321 aagtgcctcg tcaacttcac caaatgctgc aagtcctgct gctcctgccg ctacaatagg
     4381 cgcggttact ccaacagaca ttttttcacc aacgcctttt actttctcac ctgtttcttc
     4441 gattttctgg agtttttttg ctgtatcaac agaaacgtca ccttgttctt taagtgcatc
     4501 gttcgtctgt tctaatgctg tacgaagttt attttctccg gtttcagaat tgagtaattg
     4561 tttataaagt ttttctgatt cagcagaata ttcaccggtt tctttgacag atttttcata
     4621 ttcctctctc agcatttgag atcgttgttc agccaatcct aattgttttt ctaatttttg
     4681 tttagccgct cgcaattttt ctgtttgagt tgcatccttg tccatcgcag acacttggtt
     4741 tttgtactcg gcagcggcta agttcatttc tttgttgatt tctttgattg ttttcgaata
     4801 actgacttcg ccattcgttt taaaattaag aacgacatca gattctttac cagccattta
     4861 tcttagcgct cctttctacc accaaggcga tttatccata gttacagatt gaggtggttc
     4921 aaaatcggtg ttttgttgta accactgtaa ataagatttg agccacaagt taggtgtaga
     4981 ctttaaaaag aaactctcac tccaattcaa tagagtgaga gcaacgtaaa tataaaaact
     5041 ccaaggagtt cctatctctt ccgattcttt ttgtttttct ttctttttgc ttgcgctttt
     5101 tgaaagtctt gtggcttctt ggattttttt aggtcttcca cctgaaatgt ctggctagca
     5161 aaaatttcca tacaggtact ataagcagac aacacctctc cactcattcc caaaaatttg
     5221 aaaatagttt ctggatcttc ctctaaacca ccagtacgca gcatggcata aatcaaggca
     5281 cgcatgattt ttagatcact aggcgataag ttagcagaag aaatttgtcc ttctttttta
     5341 gatagcatgg cgttcatatc agattcaaat tgcgaataat ctccaccata cacatctgct
     5401 ataaattcca tcgtttgcat agtaaatgaa atagggaatt ctgcgccttg aataattaca
     5461 acagcagaat tttttaagtc ttcaacgtga attccataat cagataaccg agccattaac
     5521 ccgcacctcc aactttagcc aatgttttcc actgttcttc atcgtataca ggttgagcaa
     5581 tgaatttatt aaataattct agagaagctc cgtctctatt tgaatcaaaa cttgcataca
     5641 tcacattatt gtatttcagt ccgatggaaa ccagatttgc agttacatcg tcaatttttg
     5701 tttcttcctc tgcagtggca tactcttcgt caatcacatt ggatagttgt gtattaggat
     5761 accaaactgc ttttttaccg ccattttcaa tatttccaat aaatccaaag gcgaagtacg
     5821 gaaattctcg tgcggtattt ttgctaaacg ttactccgct tttagcaact aatcctttga
     5881 tttcatccat cacttctatc ggaataccca cgtgatccaa cgcaagttca tgttttgttt
     5941 ctcgcgacac acgacgaaac attttgctgg atgcccattt ttctaatgct gttccattcc
     6001 ctttgacacc gatttttgtg gcaattggca atcgtaaaac ttcactataa gtcggtgcag
     6061 ttccaacaga atctggcgtt gccatcatcg caattaaaat gtcgtccaat ccttcaaaat
     6121 aaaaagtatc ttgttttccc aattaaaatc acccttccca taaatcaagt atttttctag
     6181 tcataatttc ttcaattttt tctttgtttt gttcatacgt accacttgca aaatgttggg
     6241 cacgttgatt tgttgtgcca ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt
     6301 gaactttcac ttgatcgttt tcaactacta cttttatttg atcgcgcata tgtttctttt
     6361 ttaagagcga cttaggaata ttaggaagca actgctttag ataaaagtta gctgcttctt
     6421 ctaaagattc caacgataat tttttcggat caacttttga aaggtttcct aaataatccg
     6481 atatttcaga aaaaccattc ttattacttg gcattttcca cacacctcac atatgtgtaa
     6541 tagttggtta cggtatcgtc gttctcatca ccttgtatac ctgtaaaatc tgaatatgga
     6601 atgccagcat tttgcagcgc ttgttcaata acaactaaat cctgttctgt tccaagtgta
     6661 aaaaaagaga cttggtaata aggtaatttt ttatagactt taccggatgc catttttttg
     6721 ctgttactca catttgagta cacaatgtat ggatacatcg tccctaatct ggctttgtct
     6781 ctgaacactg ctaactttgt tgatttcagc gctgttttca attcatcaaa gctaatcgac
     6841 ataagctaaa ctcaactcca tttctcttgc atcgggattc gtataaatgc gagtaatgtt
     6901 atacgttaca gaatcaattt tgagcgcact taatttctct gtgatggatt tatcccatct
     6961 gactttaatt cgtctgacaa cgtctgtctt ggcttgctgt gataaatatt tttcttgaga
     7021 agtcacaccg agttcttcat agaatattag acgcttaaat tcgtaaattg tagttggacg
     7081 atcgtttccg tctgttcctg ttttgatgtc tagcaattcg gctttccatc tgagattatt
     7141 ggtctgtctc ttcggcattt tgaatcgctc cttgcacgat aaatggcgtc atggcattca
     7201 tagctttgtc gagttcatcc tctgaaactc tatattcata ggcaatgccg gcaaccatca
     7261 aaataagata ttcttgttgg ccaccagttg ctgttttgac ataatctttt gccatattta
     7321 aataaaaaga gagcaaagaa tcatccatgc cctcttcaaa atgaatatgt gatttgaatt
     7381 tttcctctaa agacaattct ttagtttgct cttccatctt aaccaccaac tggttttgta
     7441 atttcgtagc gatatactgc cggttcaaat ggagaataaa ccaattgacc atctagcaag
     7501 ttgtaaattt ggaatccaat ttgattttta ccagagaatt tttcaacaag tttttgaatt
     7561 tccaaggcac caataacttc ttgaatttta aatgcagaaa aatcgccaaa atataaaact
     7621 ggcgtgtctg gttcaccctt tttatctgct gcatctgtcc aatccacagg atagccaact
     7681 aattggtaac caattccacc ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca
     7741 tctgttttca ttttttcaat ggcagtcaaa gcagctcgat taataataaa gcgtcccttt
     7801 ttcatcactt ctgtcactgg tgtattttta aattcgatta atgcatcata taatttttgc
     7861 ccagcacctg aagcagttag atctaaaggt tttttaaatg ctacagcctt tttggctaat
     7921 gcaccaggat tttcatttcc agcgtcatca ccattgaaca tataattgat ttctttacgc
     7981 acataagctt ttttcaattc ttccacaaca atatcttcaa ctggaacacc agacattttt
     8041 aataattttt tagttactgt tgccaaagca tcgaattcgg caggattaag caaaatttca
     8101 tcaaactgaa tagctgtttc agcaatatca gttgaacgct ctttcttgtt tacattcgca
     8161 tctgctttct tcacaagaat tggatatttg acatctcctg atgttcgcac cactgttccg
     8221 tatttacgaa gtaaattttc ttcttgagca taagtaataa cttcagatgc aattacttct
     8281 gggacagtaa ctgaaccgtt gccagcttca atccctaaag ctcgagcttc tgcttcagaa
     8341 atatttccag ctacaaaatt agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg
     8401 gtcatttttg cacgtgcctc caatccgttc ttaattgatc caagtaatcc atctcgttgc
     8461 tgttgagtaa tcattccaga acgattttct gaactatctt cactgtctga atcttcttct
     8521 tgatcgttgt cttcaccaga acggctttcg tctgaatccg tactattcga ttgatcatct
     8581 gtattgtcgt ctgtttcatc agttccagaa tctgcgccta attcgtcttt aattccgttc
     8641 aattcatcaa taacactgtc aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat
     8701 tctcctgatt caactttttc acgtaattca gtcaatcgtt gctcacgacg tgccttcatt
     8761 tttttcaata attctttatc catgtatttt tcctcctacg cttctagcgc ttgattaatt
     8821 tttttgatta atttttttct ttcttcgacg tttttttcta attcatcacg acttcttaat
     8881 gcagcttctg tatcttcgta tgctggcaaa ggcacaatag aaacctcgta taattccact
     8941 tcatggattg ttcgaagcat tggttcagaa ttgtagtccc acgtttcttc agtcggcaca
     9001 aaaccaaaac tacattggtt gatgtctcct cgttccatag atttaactaa gtcccttgct
     9061 accgttgtgt ccggtaaatc aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga
     9121 agggttccgc ttttagtacg tcctagcaca ttggaccaat cgtgattgaa caaacaacga
     9181 acatccgaat tactaattgc ctttgagaat gcaccaggaa caatcacttc gcttaagtca
     9241 tcccataaaa gtgtttgact gttgaataca gcagcgtagc cgctaatggt cctcgtatga
     9301 gtttcttcat cggaacgtgt tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc
     9361 ttcatttcca tcacctcctt tcaagtcttg atcattcgtt ggtaaggaat catctgttgc
     9421 atttttctgg ccaatcctag ataagtcatt tgaaatatag atagcttgtg tttctggagt
     9481 attctgttta ggaaaaccaa gcatttctgc cacgttatct ggacttgtaa tcccggtacg
     9541 aacgatgttg tagccaatat ttgtttttgt tgagtaagga acaaaatcca aaatattaat
     9601 tttccattcc actctatagc cagaattagg cataaaaaaa agagcggtgt aatgttcgct
     9661 cttgtttttc aatattggtt tgattgcttt gttgtgcaga tacatcatcg ctttttcaat
     9721 atctgtcttc atcagcgatt gatacgtatc aacattgatt cctagaaatt ttcctaagtc
     9781 ttttttgtaa acacctaaat aattcaaaat tgccgcgtca tcaacaggac tttttaatgt
     9841 ctcgatggaa tatccttttc ccaaaggaat catcttaaca gaatgatcac tctcattttg
     9901 cgttccttcc agttgatcca atatagcttt gacaattttt gtttgggcgc tattatttgg
     9961 attgatgtgg gcgtctagtt taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc
    10021 cgtcaaaact ttttcagcgc tcagaacgcc ttctagagtg tttcttgcaa gatcaattat
    10081 tccagcacct tttaatgaat cagttccgat gttcttaatg tgtcgaatca tttgaccagg
    10141 tattttttga ccattcattt caaattcttc ttgaagtcgt tcattgattt tagttgttac
    10201 accgtacgcc aaatgaagct gatccctatc cgttaatggg aatgtctcac cattgatcaa
    10261 taaagtattt gtttccaatt tggtaaattc gaatcctgtc aaataatcat tgggactctt
    10321 caaaatattt agtaagtgat gatctttgac ttcgttgccg tcgggaccaa taacaattgg
    10381 tgtggccaat gccacctgat tagatatgtc ttgaactaat tcataaacat cagaagattc
    10441 catgatagat gaatccgtca catatctttg accataacgt gtgtagtgtc caaaaatatc
    10501 ctcgatatat ccacgttttt ccataaaaga atagactgca ttcgataacc gatcacgtaa
    10561 tttcaatttt tttcaccgcc tttctattta tctatagatg gaacttaggt aatcatctaa
    10621 ctcatctgaa tcaatatctg tcatttgatt catcgtttcc ttatgaccac acaaaaacgc
    10681 cacgaaccca tcaatctttt tctttgattg acgtttactt ggcgcttttt gtccattgat
    10741 gttagtaatt gctacaacgt tcaaagtgca ataaaggaat aatggattat caaattgaat
    10801 tcgtttctca taaaacaacc gttcgacatc gtcaaaagga gcattcaata ctttaggata
    10861 ttgagcaact tcaacgcatt ccaatcctaa gttttctaat ttctcaacaa gtttgtcact
    10921 catcgctgga tcataattca cttgctgaat atcatataaa ttcatgcagt cctctatgta
    10981 ctgcaaaatc tgatcttgat caatcatttt tccgtcgcaa aattcaacga aaccttgttc
    11041 agccaaatca ctgtaaggaa cattatcttc tttttctcga aactctaaat cttcattcgg
    11101 aataaaataa agttgcttta ctttaagaac cgctttacca tcttcatccc atgttgggaa
    11161 gtttaaagat acacaggtca aatctcgtgt acgtgataaa tctaaaccga tataacatgg
    11221 ttcgccactt aaatcaccaa gttcttgtgt ggtaactaaa catggctcta cttgatcctg
    11281 ttcaaagaaa ttatccgcgc cgttcacaaa tacatccaag tgtttcgtta gaaattcagc
    11341 tttggaatga gctgaccgtt gcgctgtttt aaatgccgat tctaaagcag ataaatcgac
    11401 tgatattccc cagttaggat tgcacatttc ccagactttt ctatccgtcc aatcataatt
    11461 tttatttggc tcatagatta gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc
    11521 ttttgcttcg cgatatacac gcattccaac agacgacgaa cctttcccag cagttgagat
    11581 attaaacatc aatggctgtg gtaaagatat ctgagcagac ttaaaattgt catactgttc
    11641 cattttctcc tgtttatgca attcatcgtt caatacaaaa tatggattgg atccctcgat
    11701 attatcaata ttcttggttt gaacaataaa tttatttgag taagccatat cttcatgaat
    11761 atagtcataa gtaatactag aaacagttcc ctttggcccc ctaaatattt tagttccttc
    11821 aagtaggatt ggattgttta agattgtaac tgcaaaaggt ttggcagcat attgcgcttg
    11881 agcaaaatca gatgcgcaag catagcaatc aactgataac gccccttctc cgtacattgc
    11941 atatcctaat gaaccgacag caatcaatgt tttaccattc ttttttggaa tctggacata
    12001 agcctcacga gtaacgcgta caatttggcc tttttcattt tctttaaccc aaccataaat
    12061 ccaagaataa ataaattttt cccagggttc taaaagaaac ggttttccca ccatttctcc
    12121 ttttgtgtga acaataaatg attctaccca atccatcatt tcattcgcgc gatctacatc
    12181 aaaccaaata tcttttcttt ttttccactg ataccagcga tctattgcta aacgaacggt
    12241 cttaggatac ttcttaggtt tctttcttac ttcttttgca aataaatcag cataatttac
    12301 accaggttca atcatttttc agcacctgcc ttcttacgcc atttatttct gtgcgctgct
    12361 agttcatcta ctggctttac ttctgggcgt gtaatttctt catcttttct tgcggtcgat
    12421 cctccagcaa ttagtctacc agtttttgct ttgtttgtta atcctaataa atctagagct
    12481 ttcatcttct tatctgccca agtttctact tgttgtgcca atggatgttt tgattgatta
    12541 gtagctcctg atttattcgt gaatttttgc gtctccggaa atcctttttc cttccacaat
    12601 aaatatttgt gttggtaaat ttcaaaaata tccaagtatg attcgattaa tggatcaaga
    12661 gtgatggtgt acaaatcaga caaattcatt atttctaaga tacgagcttt ttcagcactt
    12721 actttttcat caataatcgc tttacgttgc gctttagtcg tcatttttgt atacaccccc
    12781 ctttgttttt tgaaaaattt gacctaacga tgcgcgtgac tccccgctac cctatctccc
    12841 cacgcgaaaa aattttgaaa atgaataggg gggcttcaat tgaaatacga aggaaaaact
    12901 tttttgtctt ccgtttcgtt ttcaacaatt ggatgacatt ttgaacataa tagcatgaga
    12961 ttgtttggat caagcttaag cagttcgttg tctttgattg gtacaatgtg atggacgtgt
    13021 gctctctttc caaatatgaa ctgaccacac cgctgacaat gaccaccttc tctttcataa
    13081 ataaattgac gcatatcttt ccatgcttgc gttcgataga atggtttgtt ctcatgatga
    13141 taaacagact ttgcttgctg cttcttcttg cgtgatctgc ttgatctctt gtgttcagta
    13201 cagtagatac cctttgctat tttgttcgtg catccgtcaa actgacagta tttcattcta
    13261 cttcacgaat aagatttatg atatcgcctt ttgcacggat agcaccagga atatcaatac
    13321 catgtttctt agcatatgca cgcaattctt ttgcagtcat attgtccagt tcatccgtat
    13381 cttcagtgga ctgatcatta gtagcttcgt ctccatcaaa attagcagca gtgtttccat
    13441 cgctatcaag aatttcactg ctatgagcta tgagttcgcc attgacagca acaaatgatt
    13501 tgccatcact caaaattcct ttttcttctt ttacttcaaa atttggttct tgatctttcg
    13561 gaacaactac tgtccttttc ttttctgaat cccaatactc tgttccacta atggatgttc
    13621 taattttgat cattgccatt ttaattctct cctttgtaat ttgtacggat tacttttgcg
    13681 cccattcgct cataccattc aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa
    13741 gaaataacta acgtattcat tccagttctg taatcatcat tctccacttg cacatgtgca
    13801 tgattaccat tccaattttc tctgtacgga ctattctctg cttcaattgc tttcttataa
    13861 actttagcca aacttgattc tacttcaata ctaagtaccg cttcatgaaa atcattcatt
    13921 tgtttactct cctatcagat attttgtggt atgatttata aaaaagatgc gaggtgtttt
    13981 aatgcttcaa gaagttaata ttaagtatcg tgatcgtcaa aatacagaga caatttattt
    14041 gccaaatagt tgtccgcatt gcggaaatat aatgactccg tatgtgtatt ttggggtttc
    14101 atcatatagt gcgttcgata atgatagaat ctttggcgta ttagtacagt gtataaatga
    14161 tgagtgcaac aaattttata gtttacaatt tataaatacg tttaatgaag atgaaggata
    14221 ttctgaaaat attttaatta aagattatta ccgtccgccg attaaaatag atttaccaga
    14281 aaatattgaa aaagtttctc ctacatttgt tgatatttat actcaagcca cacaagctaa
    14341 atctgagcaa ttggaacaaa ttgctggagt tggttataga aaagctctag aatttctaat
    14401 taaagattat gcaatatcta aaaattcaga ggatgaagat aaaataaaaa aaatgttatt
    14461 aggtaaaaca attgaaaatt atttgaatga ttttcctaaa ctccaaagat tagccaaagc
    14521 tgctacttgg attggtaatg atgaaacgca ctatgttcgt agacatacta ataaagatgt
    14581 tcatgatatg gatgcattta ttaaatcagc agcgcaattt atcgcggctg attatgatgc
    14641 tgatttagct gatcaattta taaatggaaa taactttatg ccaactacta attaaaagaa
    14701 taaaagagcc acagatacca attaataaaa cggttgggat atcttggctc tttcatattt
    14761 ttttgacact aatagaatat catgctgcta acaatgttta catagctaca atgaccgaac
    14821 atttagtgaa cagtgtaatt ttagaataaa gagagttgtt ctttgtactt ctcgctattg
    14881 taaaaatcaa tttcgttttc ttttttcaat cggtcagctt gtctgtgttc atactcatct
    14941 aaaaagttca atgtctttct aatttctgca tgtcgctgtc tgacatacga tgagctatac
    15001 ccaacagatt cagcaatatc ttctaagctc atttgatcaa catatttcat cttaacaatt
    15061 tgattatcga taccagaaaa gctatctatc agcaataaca tttcttcttt ttgctcgatc
    15121 aacaattcca attcattttc tatcttttgg atattctctt ctaaagaaga agttctcgaa
    15181 ttcttttcga tgcggacgtt tgctaaatca ccacagaccc atcgattcaa ttcaagctta
    15241 cttttattaa gattccactt taagtaaaga atctgctcat ctagttcttg gtaatctttt
    15301 aaccaatgaa atctcacaaa cgccacccct tatggtagaa tagtattgcg ctgctatctc
    15361 gaaaggggta gcttttttat tttttcttag ccgttccatt ctggattgcc ttttgttcca
    15421 aacgtcgttt tttcttctta atctttgatt ttgtttttcc catacaattc tcctttccga
    15481 aaacacattt tgttcgattt ttaatactaa ataaaagttg gccagaattt ttcgttcgtc
    15541 tttactcatc tttttttgaa taagattact agcataaaaa tagttagtac cacgaaaatg
    15601 aacaggtaaa tcaattacgt tcaccttctt catgccagtt atcagccact agaatctttg
    15661 cgttagtgcc gccaccgttt tcttttttgt atttttcaaa tgctttataa gcagctgttt
    15721 ttgatttata gatttttccg gaaccgactg ggaacatcca tgtgccctct gtgatagcta
    15781 agatgtatac tttcatttaa ttcacccctt taatccccaa cactacatat ccggacttct
    15841 gcatgtaatc agtaatataa gtgatctctg ctttgtatga gtcaccagtg taactaaatg
    15901 ttggtctcgt tagtccaggt aattcatgtt taatgtattt tttatattca cgtagtatta
    15961 actgatcacc aactttgaag tcacgatcat tcttgcggat ctcgaattgt ttgcgtccgc
    16021 tcgtcactgc ttcaaaatat tctggtagta tttttagttc gtggatcatt ctgtttcctc
    16081 cttcaaaatt cgctcatcat caaaaagtga atctccacaa aatccttctc ccaaatattt
    16141 atcgttcatg tataagtcaa ccaaatattt gtgatctgct tctcgatatt cattaatatt
    16201 aacgatcttt attttgtaaa cattatcttc gtcgctcact atcttgaatt gttctctgac
    16261 tttcaccacc gttcctcctc tttttgaaaa aattttagtg tttttgtaag accccctaaa
    16321 tcagcttttt tatttgatat aatacttgta tcgattaatc aaatcgaaat taaatttaaa
    16381 aaggtgattt atcatgaata tcaacaattt agtaaaactc gttgaacaac gttttaaaga
    16441 atcaggatta gaacaattaa aaaaagataa ttctccagaa ttattttcta attttaccga
    16501 agacgacatt cctactctta aacaattaaa atattattct gattattgga cgcaaactcg
    16561 tgagaatgaa ttaaatttag aaaaactcat tattaaaaag aaatagcaac tccagcccac
    16621 acggctggtt ttttagtttc aacttccctc cttacgggtc aaaatcatcg gttccggcat
    16681 aatctgatca tcctttagca acaaatcagg atattttttc cttagcttct tattgttcgt
    16741 gtaagttttc aatagccatt ggttggcttc gcttttgctt tctccagaaa aataaatttt
    16801 ccctgtttgg atgcctgcaa gttgaatcat cattttcacc tcaaatcaaa tttttttctg
    16861 ctagatggag caaaagcaat ccgacatcaa gaatcttttg acccattatt tcagctactt
    16921 tgctcggctt aactccttga gaaaagagca agcgtgcttg ctctatctct tcgtgagtcc
    16981 aaataaattt ggcttcctca aggataatta ctggatcagt tgctctcatt gttcctctgg
    17041 aaaaatgatg tcattcttat gcttggacca ggtatctgca tatggaacaa agtattgtct
    17101 agctaattcg atttgatcaa ttaaagcagt ttctgataat tcatggtctg cagcaatttc
    17161 attcatacta tcgccttcat ctaaacagat aagaccgttg acgttatcga tttttacatt
    17221 tgtgactgct tgactttctc cacgctcata atattctaca gttgatactg atacatcagc
    17281 ttcggagttt aattgcagaa tctgttactg ccgggataat ttaatattct tttcataatt
    17341 cacctttttt cctactgaca tcgaatattt ttcatgttat gattagccgt gaaaggagag
    17401 ctatattatg tgtttacaca tgatgtcctt agctcattcg gttctttgga agcttttttg
    17461 gaaataactc tcaggttctt gacgcaaatc tcatttattc tttgaaacaa aaaacttcca
    17521 ttttccgaga gctttggatc acttcaaaag agatttgcat ttatatttct gtgaccttga
    17581 gtcgcgtaaa gaaccttaca gcaatggcgg caattccact ttcaggaaac cgcctttttt
    17641 cattgatatt ggtggttagc ggactaccca ttttctttcg gcagtgccaa accacaaatg
    17701 atctgtgttg atgtttaggt agttgtatac cagataagct aaatccaaag tgcctgcatc
    17761 ttcaagacga caatattcca aaaattctcc catagctgga cataaaaatc ctggagctat
    17821 catatcccaa cagttaatag tgcaaagaaa ttcgtttagc ttctgaacgt tttctttggt
    17881 ttcacgaatt acaacatact ccaattcttc tccgctggca gagcattcca aaacttcaaa
    17941 ttgattaaga aatggtagaa catatgcttc aaacatcaac attccatctt tctgtttttg
    18001 cacttgtttt gcatcaatca tgtctatcct cctattcagt tatttcttcc attaatggaa
    18061 ttatttcagg tcactggact taacgaaaac accattgacc atctttccag tccgaccttt
    18121 gatttcgtca taagcaaaat ccaagcactc gtataaatcc atatcatttt gcattgccaa
    18181 gatgatcaag gttactacta catcgccaat tccgtctctt aaaccatgtt catcttttct
    18241 agctagagaa gcggcaactt ccccgatttc ttcgaccgtt tttaacattt gcttgctgaa
    18301 atccgcttga tccaatccct tatcttttgc ccactgctct actttcgcga ttagttcgtc
    18361 cattatttct cctccacata cctaaactgt cttccttttg aatcaatcca taagctccta
    18421 gctctatccc aaataatatt tttgctcaga ccagtaattt cagataactg tttagcggta
    18481 cccgttacta gaattcgatc accatgccag attgcaatct ttctcggcgt tctccgtttg
    18541 ggcttttcag tccacattga tttaccgagc ttttggactt ctgcaactat ttttttatct
    18601 tcctgccaat cttctgaata agtcaattcg ataattcgct gcattgccgc tttcttatcc
    18661 atcccgacat tctcctttca gtaatttgag tacttgatca agtgcgctct cacgtccgcc
    18721 atgaaatgtg ttgagccact tgtcttcgta cgacacactt tgtcttaaag cttcttgatg
    18781 cattaattcg atctgtgctg taaatgtctt taggtccatc ttgtttacac ctgctcaagt
    18841 tcattaagat gtttttgcaa gcctttaaca caatcaatga atagtaattt ggtatatgct
    18901 aaatttctta attgcgttcc atcgatatag agtgcgaaat agtatctgag tttactccaa
    18961 ctcgaacgat cattcttaat tccttcaatt ccagcttctt cgagttgatc atatacgtct
    19021 ctcaggacgt ctaattcctc gcccttttta taattcgcta tttcattaat tagttctaga
    19081 taatcgatct tcatttttcc acctcttaga atggtgcttt tgattgtcta ttagctcgtt
    19141 ctagcgcttt tttcttgaga taggcttctt ggtcgattgc ccattcagga agcttctctc
    19201 gtcttcctgt gcgcttgtat ccactgcttg cgttcttagg ttcacttttt tctttccttg
    19261 cccaacttcg aatagttgcc aaatagtttt tataagtctt accagatgat tcacaatact
    19321 ctgacagtcg ttcgattcgc tcttggtaat cattagggaa ttctgttttg agtttctcca
    19381 tctgctcatc tgacaaaaga acatttttat actctccgta tttatgacgg acgggcttag
    19441 ccttcgattt tttcgaaggc ggtaactctc ttatatattc ttttgtatta ttaaatgtat
    19501 tattaataga tgtattatta tctttgactt tttcgtcaat aggggtattg cgtttttcgt
    19561 caatagggta ttgattaatt cgtaggtacc tattgattat ttgattggta ccctctttgt
    19621 aaatgatttc ccgattcaag tatccaaact taatcaaatc acttacccat cgcgatatgg
    19681 tctctttatt cacaccatat aaatctgcaa agtactcatt gcctgcccaa caaaagcctc
    19741 tttcattaca caaggccgtt atctctccgt ataacaactt agtatttggt ttaagtcttt
    19801 tgtcgtacct tacgttggct ggtataatcg cataataact tcgatgttct gtcattttta
    19861 ccctccaata tttaactttt tgattgtttt ctggtttaat ttgatccctt tgatttgata
    19921 tttatttttg aaattaatca cacctatttt gtgcttctct gtgtgatgga ttctgcagag
    19981 tgctgcaaat gtgtactctg catgatcaac ttctttgcgc tttcgtcttc ctagcgcttt
    20041 gtcaaagtga tcgatgtcag ctcctgtttt gccacagatg cagcagactc tttttgtgat
    20101 gcatttgtag aagtaatatt cttgattcgc aggtaaaatc tcatagcctt ctttgaaagg
    20161 aatatgatgt tcaaagatga aatctaagat gatatttgct aagacattgg catcactcac
    20221 agttgtattc gattcgtctt tcaggcttat tttgcgccct gtgacacctt caaaacgaaa
    20281 gtagaagaat tccttccaga agtccgttgg catgcctgta tcgataaaaa tatcgcctat
    20341 cagcgcatag atgaagtttc gttgctgtac ggtgaaacgt ctaggatcaa taaaacgaat
    20401 ttcaatgact cgatc
//
LOCUS       DASHWW010000048        20206 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.048, whole genome shotgun sequence.
ACCESSION   DASHWW010000048 DASHWW010000000
VERSION     DASHWW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.048"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..189
                     /locus_tag="U2R64_001934"
     CDS             <1..189
                     /locus_tag="U2R64_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8918735.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1585)
                     /locus_tag="U2R64_001935"
     CDS             complement(1055..1585)
                     /locus_tag="U2R64_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HEM8918736.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVMGKHCWIGAKSVI"
     gene            complement(1582..2199)
                     /locus_tag="U2R64_001936"
     CDS             complement(1582..2199)
                     /locus_tag="U2R64_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEM8918737.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2805..3002)
                     /locus_tag="U2R64_001937"
     CDS             complement(2805..3002)
                     /locus_tag="U2R64_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HEM8918738.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYK"
     gene            complement(3180..4712)
                     /locus_tag="U2R64_001938"
     CDS             complement(3180..4712)
                     /locus_tag="U2R64_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8918739.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4848..5933)
                     /locus_tag="U2R64_001939"
     CDS             complement(4848..5933)
                     /locus_tag="U2R64_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8918740.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(5948..6667)
                     /locus_tag="U2R64_001940"
     CDS             complement(5948..6667)
                     /locus_tag="U2R64_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEM8918741.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6664..7974)
                     /locus_tag="U2R64_001941"
     CDS             complement(6664..7974)
                     /locus_tag="U2R64_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEM8918742.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8001..8591)
                     /locus_tag="U2R64_001942"
     CDS             complement(8001..8591)
                     /locus_tag="U2R64_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEM8918743.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(8909..9970)
                     /locus_tag="U2R64_001943"
     CDS             complement(8909..9970)
                     /locus_tag="U2R64_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8918744.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10538..11605)
                     /locus_tag="U2R64_001944"
     CDS             complement(10538..11605)
                     /locus_tag="U2R64_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8918745.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11625..12104)
                     /locus_tag="U2R64_001945"
     CDS             complement(11625..12104)
                     /locus_tag="U2R64_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HEM8918746.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12121..12582)
                     /locus_tag="U2R64_001946"
     CDS             complement(12121..12582)
                     /locus_tag="U2R64_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8918747.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(12596..13846)
                     /locus_tag="U2R64_001947"
     CDS             complement(12596..13846)
                     /locus_tag="U2R64_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEM8918748.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14224..15675)
                     /locus_tag="U2R64_001948"
     CDS             complement(14224..15675)
                     /locus_tag="U2R64_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEM8918749.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(15996..16760)
                     /locus_tag="U2R64_001949"
     CDS             complement(15996..16760)
                     /locus_tag="U2R64_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEM8918750.1"
                     /translation="MIDLHCHILPGIDDGAESLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16788..17486)
                     /locus_tag="U2R64_001950"
     CDS             complement(16788..17486)
                     /locus_tag="U2R64_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HEM8918751.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17498..18277)
                     /locus_tag="U2R64_001951"
     CDS             complement(17498..18277)
                     /locus_tag="U2R64_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HEM8918752.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            complement(18293..19237)
                     /locus_tag="U2R64_001952"
     CDS             complement(18293..19237)
                     /locus_tag="U2R64_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8918753.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19283..20062)
                     /locus_tag="U2R64_001953"
     CDS             complement(19283..20062)
                     /locus_tag="U2R64_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918754.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
BASE COUNT         6407 a         4035 c         2606 g         7158 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgtaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acccataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
     1861 taactctttt gttccagttg ttgtattata cttataaatc caccagtctc ccataacatc
     1921 agataaagga tttaaccaaa ttgttcgatt gattaatgtt gtaaataaaa tcatcgcagt
     1981 atagaatatc aaagcacaaa cttttctata ttttctatcc ttctttaaat gaagataaag
     2041 ttccattagt atacgtttat agccctcacc tgcagcaatg ccatctgttg catacataaa
     2101 atagaccagt cctaaaattg tcaataaaac agcaaaccca aagggttcat ataatttata
     2161 taatatatct gtaataattt ctgcaatcac tattatcata attatttctc caatatcaag
     2221 tatacactta tcgcttccaa ttacacatga tcatattaga gtgtattatc acattctcta
     2281 atattcaatt tatttttcct aaaatattcg aaataatcgt cttgataacg agtaagtatt
     2341 tttatacgat tgataacata gtaacaatat ttttaattat agtaaaaaat catctgcctt
     2401 tttcatccac ctaatcttat ttttcatttt attcaacatc cttaaataaa cttccgttcc
     2461 taagctctat aatatcttct taaaaaataa tattatggtg tcgttttcaa actcgtaatc
     2521 ttttacattg gaaaaataca tacttttctc aatgtagcaa ctcctatctc acagtattca
     2581 aaaattcttc aatattatga aatacttgtg catgttcttt aaataccttg tcagtctgtt
     2641 tataatcccc tactaaattt tgcattgctc ccaactcttc gacaaattgt catctccatc
     2701 tgtaaacagc cctaaaaact catataatgc tttttcatca atatttttcc catattattc
     2761 tcggtatagt ttcacaagtt ttacggattc ttcatattgt ttatctattt ataatattca
     2821 tctagggaca taattacttt tgctagattt cctgcaacaa cacaatcgtc tgatacgtcc
     2881 ttgtttacta aactatttgc acctataact acattatttc ctatatgtac accctttagt
     2941 attctagact tcattcctat aaaaacatta ttacctattt tgatcctctc cgatgatccc
     3001 aaagcttctc catactactt ttaaaaccga tcaatcataa acatgagtca aaattgtaac
     3061 tccttcatat catctccaat ttcaacaaga gtcttcgttg gaacaaaaac tatacatcgt
     3121 tcgcctattc ggcagcctaa aaattgtagt tactttatat atcattctga tgtctcttct
     3181 catcttttta ccaataccga cgtaagaact ttcaaaatat acttaaactt cttattacgg
     3241 atattaaaca gaagaataac taaaatcgat atgacaaccg atataactaa atttatcact
     3301 aaacttatca ctttgaaatt tccgatatta acatacgaac aagcaaaata acttaaataa
     3361 gaagcaacaa aagctattac acacaaactt atgagcttcc aaacatattt acctgccgat
     3421 tcaaatttaa atatattttg gaaaacatta tataataacc agggtaaatc aaccaacaat
     3481 actgaaacaa tggttgccgc caaaactcca tataatccga accaattaac gaggatgata
     3541 tttaatacaa tgtttatcat tgctgtaatt aatggtctaa acctgtctgc gtaccatatt
     3601 ccagcagcat ctttgtataa cccaattaac tgatcaattt catataagaa aaaatgaact
     3661 atcataaata taacaaatga aatactcata agattatcac ttcccaccca gataatcatg
     3721 aacggctgaa ataatgtaat aaagcatgca caactaattg ccagaaacca acctataatt
     3781 gttgtaatat cacaaaaatc tatataattt ttttcttgac tttctacaat aagactgtta
     3841 cctatacctg ctatacatga ttcataaatt attgcaaata tactcattat ggcagaaata
     3901 ataaagtaat aattctgata aatcgcaagt actgaaagac ctaagaaaga tgaaataata
     3961 attgaatctg aagatcgtaa tattgtaccg cctaccttgt ttgtaactaa tccttttact
     4021 ttttttataa tatcgtcaat agtttctttc tctaactcac caacaggagt ataatcagga
     4081 tacatctttt gagaaacaac agcacacatt aagttaagaa ctatttgtcc caaaatagaa
     4141 gccaataaat acaaatagta attttttaag aaaatcagaa catatgcctg cattacaaat
     4201 tggaatgtaa aagtaattag catagacacg ttaattacat catttctttg atgtgcatat
     4261 attagactct ttctatatga aaataaccaa tacgacaaaa cagtatttat caaatacatt
     4321 aaatacaaaa ctgtcatatt taaatttcca ggaatcgaac ctttaactaa aaatctcaaa
     4381 aaaggaatgc ataacaatcc taatgtaaac actatccatc caataattga aaagtacttt
     4441 ttatatgcgt tcagtaaagc acaaatctct tttctattgt cttctgctat aggtttatac
     4501 atacttacag ttagtgcagc acctattccc aattccgcta aatttaacat ttgaaatata
     4561 gatgtgaaca ggttgttcaa tccagcatac tccattccca tctgataaat cataagtgta
     4621 cgcataaaaa agggaatgat aatctgatat aacttaaaaa ttgttccagt aattatattc
     4681 cttttagcat tttgtttacg attaattatc atatcatatg gctccaaact ttctattttt
     4741 tattgttacc taatactata taatttctaa aatcttgaaa tgtaataggt ttcttctagc
     4801 tctttgatta attacgctaa ttttcatgtt tggacaacca caaaaaacta tacattttca
     4861 atcaaagcaa cccattgttt tgtaatttct ttcaaattaa atttttgtac attattatat
     4921 gcgttcagtg acattctcat tgctaaatca gtattcttag taaacattat catgctctta
     4981 gctaattggt ctatattctt atcttcaacc aacatcccat taaaattatg atgtaccaaa
     5041 tctctcggac cagttttaca atcataagaa ataactggta atccataaga ctgtgcttct
     5101 aatataacca taggaaatcc ttcataaaca gaactaagca cataacaaga tgcagattta
     5161 taatattcct ccacatggtc tgaatgccct gctatagtta ctctttgcag atttaaatct
     5221 tttatctgct ggcgaagatc tttttctaat tcaccttttc ctacaatgat aagatcccaa
     5281 tcatctactt ttttttctac aattttccaa gcacttatca tgtcagcaaa atttttctct
     5341 tccactaatc gccctactgc aagaaatctc tttttatcat aatgatattc gtactcgata
     5401 ttagatatac acggatttgg catagttata acaaaatctt ctgataaact atattcatca
     5461 atatgttttt gacgatcttc ttctgtgaga accacaagcc tctttgcata tttttttatc
     5521 aattttttag ccttgaatct cttcttttct ttcagcattt ccattgtcca gtaattaaaa
     5581 tgttcccaag aaatcaattt gcactttgtt cctttaattg cccttgtagt atacaaagac
     5641 aacaaagtat caatatcaat tactatatca aattcatttt tgcatatata cttgtgcaat
     5701 ttccaaaccg gatataaata agttctatat aattttccct ccgttttagg atttaacata
     5761 taatcaacct taatcgtctt atctaaccca aaataaggct ctccactatt ccaaaagctt
     5821 aaaatagtga catcataacc taaatcagac aagctattgg caataatact ccctactctt
     5881 tcagttcccc cagaacgaga aattacacca ctaatgaaac aaattttctt caaagtactt
     5941 ttctccttta taagtgtaaa aattttttca gtgcaagtaa cctgttaaat tttttttgtc
     6001 caattgttga ttttaatcta taaacaaatt tttgtttagg tgttttccaa gatgcattat
     6061 attgatgaat gcttattgta ttactagttt tataaatttt tccagtatca taatccttgg
     6121 cagcaaaata atccgtagga tagatatgca ggccatttat tatttgttcg ctgttatcgc
     6181 gaaccaatcc aatagattca agataatctg taatataata cggactcggt ttcaagttca
     6241 atgtaccatc attttgataa aaacttaatg aatcgtaaat atcccttaaa cctttaataa
     6301 cagaatgtcc ttcttctgca ccaaaaccaa taccgccatt aacccagatt tccccttcaa
     6361 atcccatata ggcatgattt tcacgaagta tatctaacga cttaattagc tcaacatctg
     6421 tatctaaata aaatccacca tgattataaa taatatcaaa tcttgcataa tctggaacaa
     6481 aaccccattt acgttcttta tatgcatcgg ccatataacg gttcttattt aaatcataat
     6541 ttgattcatt ccattcaata atctcataat cagggcaata ctttttccag ctttctatgc
     6601 actttctatc ttttttcgga agtggatttc ccccgaacca acagtaatgt atcttcttag
     6661 gaatcataat atctctcctt ttgtattttt ttcactataa taatgctctt tccttttcac
     6721 aacttcaggc atggctaaaa tcatataaat cagtggcccc gttgtttcac ccctaagtgt
     6781 tgtgttatac acaaaaaaga ataccgacat aattgcaata actttaacaa gacttgcatc
     6841 tttatccttc ataaaagatc tttttgcatt gaaaaatgtc tttattataa aaaataggaa
     6901 tatcgaaact cctaatattc caacttctat aaataaccaa atatgatgaa aatactgata
     6961 atgaagatta ccaaacgatt tataaaactc actgacaaaa aaattggtaa actctgcatt
     7021 gccaatgcct actcccatta ggactaatct aaaattatta ttaaatattt catctactac
     7081 tctagagata ccagttattc gatttaaatc accaacacca tcatatccag aatctcttga
     7141 cgcatattct aaaagacctt gaattgtgaa attatcagca tagctttgtc cattatcgtt
     7201 caatgtaata aatattgtta taaaaaagga taatactatc gacacaagta ttacgcatga
     7261 taatatcttg atcactactt taaaatcaac ttttaaagtg aatactattg caacaaatat
     7321 tataaataat tcaggaataa aaactttcaa ttcagctaat gcagacataa aaagtgctgc
     7381 acaaacacat aaaataaaat ggatgaaatt tttttctccc ttgaaatatc cgattgtaac
     7441 aacagtaact gtcacacaca aaattaaatt caatggcata ttacaacctg aataattcca
     7501 aaaaactcca cctatcatat ctcctacaat tgttccagtt ggataggtga ccatgaatct
     7561 ttcaattaaa caaagtggca gtgaaatcca gaataatttt tcaattatag cgaatacttt
     7621 atagtaatct ttaattgtta aatatgttgc acaatttata tatactatga acatacgagt
     7681 gttatttcgt atcccccaga taatcaatcc tatattttct aaattaataa ctgagctaca
     7741 aatagaaact agtaaaaaca aaactatcag catctcattt ttgctagcat atattccttt
     7801 tctgcgtcta aagctaagtg catttaataa cacaaagata ttaattatat ctcccaaata
     7861 taaaattgct cttggggcgt taaaagtata tacaagaact atggagattg caaaaaatgc
     7921 caacgtgaac aatgtccaat ctgctcctga ccatcttttt attgaaatac gcatcgttat
     7981 tcaccttctt tcgctaaaaa ttattctaaa aatacttttg ttaaattaac ataccctatt
     8041 atttttgccg gtacacctgc aagaattgca ccattctcta gacaatcttt gataacaata
     8101 gctcctgccg caacaactac attgttagct atttttacat taccaataat ctttgcaccc
     8161 acgcatacac gtacattatt tccaattaca ggacacttag gatcgattcc atcatttcca
     8221 atacagttat tcccatataa gtaacaattt tttcctatta tggcgttacc attaataaca
     8281 attccttgtg tatggtaaaa tcttacacct tcatcaaata cattttcacc acactctata
     8341 ccacattttc ttcccaaact attcattctt ctgcaagaca caatatacat aatcgcataa
     8401 atgatatttt tctttctctt tgaataataa taagatgtaa ttctcattcg acgagtatac
     8461 cgccaagcgt tgtagtccgg atgtgatttc attattttta gtaattttgt gtgttgtcct
     8521 ttagattcta tatatagatt cttttccata cgaagaaccg cttttaaata ttctttactg
     8581 ctaatttcca ttcatatctc ctattaattc aatttatact taacaatttt attcggattt
     8641 cttgcaacaa gagcatcatt caatgctact gaatctacaa cgatggatat gttatcttca
     8701 tcgttgattc caccggatac aatattactt ataaaaatcg taacattttt tccaaaagaa
     8761 gggatgtccg tgatgtataa tgcccatttt ccgatatttc cagttattta aacctaacga
     8821 atttttacaa tagtacaagt atcacaatca ttaatatata actggaatat aaatctccaa
     8881 aaattcacta tagtacagtt ttttatgatt aaaatctcct atttctaccc attccgctta
     8941 aatatgctaa tgttttaacc ccaataatgg attggtttag taaaaaatag ttaaatattc
     9001 gttgtttaat tggattttgt ttatatgggt atgagtgaat acaggcaatc aactcatcgt
     9061 tcataagtat cttagacaaa taggagttta aatcaaattc tttattaaaa ctagcatatc
     9121 taactgcctt ttgaatacaa gtacgacagc gtcccaacaa aagtctcctt gttttgttta
     9181 caaatatctc attttctaat atatagctta aatcgccttc aattttttta actaattcaa
     9241 tattacaatc gaactcatta tctctaaaat tatgtgtcaa tgaattatta ttattacatc
     9301 tataataata gatacaatct ttaataaaac ttgttatttt tgaatgttgc aaatatgaaa
     9361 tatggaatat gatatcttca gatatataat ccctttctga cggaaacttg atattgtgct
     9421 gttgaattat ctcagatgaa tacagcgcat gccaaactga cattggcaat ataaaatcga
     9481 ctttataact cggctcagtg ccaatcattc caagcaacac tttttcaatt atagcgttat
     9541 ttgtaaatat cgtactatca tatcttgctg gctttgaaat aatattatta tcatcataat
     9601 attcataata tccagcataa catgtgtctg cattactcct ttttatacca tttaacattg
     9661 cttcaatata attagctgca acaaaatcat cagaatcaat aaaagcaaca tattttcctt
     9721 ttacatgttc aagtcctgta tttcttgcca atcccaagcc agcattattt ttatgaataa
     9781 tacgaatcct tgaatccttt aatgcatagt cttcacatat tttattagat gaatccttag
     9841 atccatcatc cacaattata atatctaggt tcttatatgt ttgattacac actgattcca
     9901 aacaacttcc tacatacttt tcaacattat atacaggtat gattacacta attagatcac
     9961 tcgaattcat ccttctatcc tttcactcac gttttctcaa ttagtcaatg acggcatcaa
    10021 cgattttctt aaattctctg aaaaaaatag actctgatct tgatgatgtg aatgacatac
    10081 tatcttcttc tagaaaaatt atttccttta aattatttat taaatcaata atatgatcct
    10141 cgtaagtatg ctttcccttg gaataatgaa aatatacttt tgtattacac aatattgcaa
    10201 ttttatttct taatatgatt atttcactca ttcattactg ccacatatac acaacttata
    10261 accaccccct gcaaagttta gggtaagtta tcagataata tcttcctctt catcatccag
    10321 aatacaaaat ctatttattt atagaaatat cattaatgtt tttatataat gtaccgtgct
    10381 tgtactcttg ctctattaca agcactaaaa cactactatt catttgaatt cttacacgga
    10441 taaaaattta catcgtctat ttcaatattt tttctctcta ttttattcac ttaataagtt
    10501 cattacataa tcgaaacatt ttttattttc cttgtcatca ctccttgctc cctttttgat
    10561 acagatttaa aattctatca aagaaatttc catcgttaaa tttcgttatt gccaaatcct
    10621 tcgaacaacg tgaaaatttt acgtatttat ctttatcatt gatttttagt attgcagatg
    10681 tcaacgctga tacgtcacca ggttgaaaca aatatccatt ttctccatca cgtactgctg
    10741 aagaaatatc tcctacatct gtagcaatta caggcattcc ataagaaatc gcctctagaa
    10801 tagatatagg caatccctcg ttataggacg gtaaaatcat cacatttgat cttctatagc
    10861 actcctcctt tttttctccc acaacccaac ctgtaaattc aaaatacgat tgcaaattat
    10921 attcttctat caattctttg agcgatattt cttcatcacc tgctccagca atctcaaaaa
    10981 taaacttttt ttctggatat tgttctgcaa tgtttttaac tgcttctacc aaatcgtgta
    11041 caccttttcg ctttatcaaa actcccataa acagaaatcg gcacattttt gaattccact
    11101 ttatggtata ttctggaact acaatagaat tttctacaac aacagtttta caatttggct
    11161 caatttcttt aattatcttc ttccattttt ctccaagtac aatcgtggaa tcagactctc
    11221 ttaacagcaa gcgaatctga ttttgttttt ttacagaaac actatcatac cattttttaa
    11281 attccgatcc atgaagatgg atgattacag gaatatttaa taatctaaac cacttattca
    11341 gcacatattt cctactaaaa ctccctctgt acgacatgtg catatgaata atattaggtt
    11401 tactcaataa agagatacct ataattttag caaatgcata cataaaatat aaagatttaa
    11461 atattgcatt tccaccctta taactcggta taaaagtcat ctcgatattc tttttttccc
    11521 aattaaaatt gagcatttgt gtaattatac ttgtaattcc accttttacc gagctgtcat
    11581 taccaatcat aagtactctt tgcataacgc tttactcctt atatttatat tttttctatt
    11641 aatacctcta tcgaattaat aatcgtttcc gtgttagata catacttgtt aaacatccga
    11701 actcttgttt ctttaacggc atcttctaaa ttttctaatt cataacaagg atagataata
    11761 ttcatctcat caaattgtct aattaactgc agttggtgat catcgacatg ctcaccatac
    11821 ttagccaatc gaggaacagc aatgaccctt ttaccttttt ttacggcccc aattatagca
    11881 cctgtacctc catgagtaat caccatttct gctttttgca tagtttcagt aaactcatcc
    11941 ctatttagaa atgctttata ggaataattt agtggtttat aatcactata accactctgt
    12001 gcaaatgtac tttcgattat tactcctttt tcaattaaat catcaatagc ttttaacaat
    12061 ctatcaaatt gaaatttttg tgaacctaat gttataaata tcattttttt ctcctattat
    12121 ttaatatatc ccacccaaat aaatagcatt aggataaaat tgtagcatag tttcccactg
    12181 aacataaaat tgatctgcaa aatgatacat caattttcct gtctgagtag ggctggttac
    12241 ttttgcaaac gattcaatat aaatcagttt ttttcccatc atttttgtta ttaagcagat
    12301 agggatcata gctaaaacac ctgtacaaat cacgagatcc ggtttttcct ttatatatat
    12361 aataattgat ttgaataaat taataagtat agtacacaaa aaaaactttt cttttctatt
    12421 tacttgtctc atgtagtacg ttttttcgcc ttttgactca gctgaatatt ctgtctgttc
    12481 tgttataaca aaactctcat acttctccat cagtggtttt aacatcatta actgttcata
    12541 atgcccccca gaggaagccg caaaacatat ctttttgttc atattaacct ctctatcagt
    12601 cacgctgaaa aatatctcta gtgtaaactt tttctttaat atcatccaag caggtatcat
    12661 atcgattggc aataatagaa tcacacatcg ccttaaactg ctctaaatcg ttgataacct
    12721 tacttccgaa aaaagtctct ccatctttca gtgcaggctc ataaatcacc acagtcgcac
    12781 ctttagcttt tacgcgcttc ataactccct ggattgaact ctgacgaaaa ttatcactgt
    12841 tgctcttcat ggtcagccgg tatataccga ttaaaactgg attttccctg ttgacatcat
    12901 actgattata ttcagcgtag ttgtaatagc ccgccatctg aagaacacga tctgcgatga
    12961 aatccttacg ggtacgatta gattcaacga tagcctcaat caaatttcca ggaacatctg
    13021 catagtttgc caacaactgc ttggtatctt ttggcaagca ataacctcca tatccaaagg
    13081 atggattgtt gtagtgagtt ccaatacgag gatcgagaca aacaccattg attatctgct
    13141 gagtattcag ccccttcatt tcagcataag tgtctaattc attgaaatag ctgactcgca
    13201 gtgctaaata ggtatttgca aacagcttta ctgcttcggc ttcagtgaat cccataaaaa
    13261 gagtatccac gttctcctta attgcacttt tctgcagaag tgttgcaaaa acatgagcag
    13321 catttaacaa gcgctcatca gtcatatcag taccaacaat aatacgagat ggatacagat
    13381 tatcatataa agccttgctc tcgcgcagaa actctggact aaaaataatg ttcttactcc
    13441 ccgttgtctc acggactgat tcagtgtagc caacaggaat tgtagacttg atgaccatga
    13501 tggtatcagg attcacgtcc atcacaacct caataactga ctcaacagca gaagtatcga
    13561 aatgctgagt acgactgtca tagttagtcg gtgtagcaat aacaacgaaa tctgcggatt
    13621 tataagcgct ccttgcatcc aaagtagcag ttaagtcaag ttctttttct gtaagatact
    13681 tttcaatata ttcatcctga attggagact tccgtttatt aatcagttca atcttttcag
    13741 ggataatgtc taccgcggtt acctggtgat gctgcgccaa tagtgtggcg atactcaaac
    13801 caacataacc ggtgccggct actgcgatgt tgtacttttt cttcacaata tctcctcttt
    13861 cctctcttaa gtatggagaa tgttactcct acggctattc atcatgtcaa aataacacag
    13921 cttagaatgt tgataaaata attttccaga atgtgataaa atctctttca tttataaacc
    13981 acacatctaa ttttatctat tctccacaag acatgtagag tattctttaa taacaagata
    14041 cgaccttact aaatacttca aaaaattatc atatttaatt cataaatata aatcttcatt
    14101 ttaaatgtat gcccaaaaat ttatctgtaa tgcgtcatca aaatctagat tccaaatctt
    14161 tatcaatttt tatccactca ttctaccact ttagtaatat tttctattta taacactttc
    14221 gtcctacatt gatccccccc tctgaagtac agtttttact gtcttaaata aaattttaaa
    14281 atctaacccc atactccaat tttttatata ttccgtgtca agttttgcta cttcttcaaa
    14341 atcagtaata tcacttctac cacttacctg ccacattcca gtaattcctg gcttgatagc
    14401 aattcttgca cgatgatgat aatcatattc ttcatactct gatttaaggc atggtcgaaa
    14461 tcctataagg ctcatctttc ctgttagaac gttgaaaaat tgagggaatt catctaaaga
    14521 cgtggatcta ataaattgac cgattcctgt cttttttgtt ccatctggaa gtattttatt
    14581 tccgataatt cttggatcaa actccatctt aaacataaga ttattgctca tcttattttc
    14641 tttcattaat tctacttttc tttcttctgc atccatatac atacttctaa acttatacat
    14701 cttgaacggt ttaccattct gacctatacg ttcttgtgca aagaaaattg ggcctggtga
    14761 attaatataa ataagtggag caataaagat aaaaataatt cccgttgcaa tacatccaac
    14821 aatacctgca agaatatcaa ttgttcgttt tataaatgcc tgttgagttg tcataacatt
    14881 gatacttgtt gtaagtactg tatattctcc tatacgacca atagattgtt ttcccaaagc
    14941 actatctgat acttttgcaa gattcaaatg tacagtaagg cccatttcag agcatcgttc
    15001 aataaattct ttcatacacg aagtactttt attcaaaata ataaagactt catctaccca
    15061 tccctgacat aagtaatccg ctgcattttt ggaatcagaa acaactgtca ctccctcaac
    15121 atcttcacca atcatgcttt tatctatgat aatgacacca tttattttat acattttata
    15181 gttatgctct ttcacattac gaataactac ttcagcaata ctactagatg taactataat
    15241 aagtgatttg ttcccctcat ttttcatttt atgtttcaag taatgtttcc ataagaggcg
    15301 agttatatat gtaattacaa cgtataaacc tcccatcaag aaaagaacga ctctagaata
    15361 atcatttcca ccctgaacac taatgagata caaacttcct aacagcacca acataatcgc
    15421 ttgctttaca gaagaagcaa attctatata gtaccctctt tttaatacac ctctatatgc
    15481 ttcaaacatg aaaataacta aaagatctgc cagttcaatg aagactgcca tgttttgata
    15541 cattggaatc acataaggat tccaatctac ctggcgtaag acatacgata gataaaaagc
    15601 aagctggata cacaataaat ctaaaataat aaaatcaata tgtttaaccc atccccttga
    15661 acttttcttg tacattcctt tttactcccc tctttttaat aaaataaatt gtattacttg
    15721 ttttctctcc taaatatctt tctgaaggat tattgactcg acaaattggc ttgtggatat
    15781 tcttatatat agaacatccg taagccaact taaaactcct taacaaaatt tttttactca
    15841 tattgtagat caaaacaagt atccaagaaa tcatatttta tttctttttt ctgcttactc
    15901 aacaacagct aaaagaaaaa tcatcataaa caaattcaac taagccaacg atccccttgt
    15961 gaaatcaagt tttttcttga tttacgaata aagagctaaa ataaaccaaa cttcttcttt
    16021 tttacctctt catagactgg ataactgatt tcatccccgt tgatcagatc ctttgcgact
    16081 tgtttcatct gtactacttt ttccttacca aagtcctttg caatctgctc atagcactct
    16141 tttaagtaaa aggtgcgctt agagacccca tgggcatcag aagcagccat ctgcacgaga
    16201 ttatgtttga ccatcgtttt ggctgttttc tggatgtctt tgccaaatac cccaacataa
    16261 cttggcgcag tgagttgggc caaacatccc atatctagga acggaagcaa atgatttggg
    16321 tcttcgcgaa aatgcacgtt gcgttctgga tggacgatta ctggtgtctt tcctagttct
    16381 aacaactcaa aaaaaagccg ttctgcatat aacggcactt ccagtgtcgg aaattcgatc
    16441 agaagatatg tatcatctaa atctgtaaat aatatttcat ctcggtggat gtcttcgatg
    16501 agcgttccgg taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ctgtcttttc
    16561 tctaattcgg cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat
    16621 tttccattat tgtggtgtgg tgtgcataaa atatgcgtga tgccttgctg aatcgctttt
    16681 tcagccattg caatacttgc ttctaagctt tctgccccgt catcgattcc tggtaggata
    16741 tggcaatgta gatcgatcat ttctcttgtc tcctctcttc ttattcctta atttccgtag
    16801 taataaccag catctttgct atgttctgct ccgttgtaca caacacctaa gactcgtgct
    16861 tgtaccatct ccagcagttc ttttgcttta gtcaaggatt ctttacgtga catattttca
    16921 cgtacgacca ataaagtgcc atccgttttt aaagacatga tctgtgcatc tgttacggct
    16981 actactggtg gcatatcgaa tatcaccacg tcaaataact gtcttgcttc ggataggatc
    17041 tgatccattc ttggcgagct taacaattct gatgggttgg gtggcttagg tccactaggc
    17101 aaaatcgaca agttctcgac tggcgttcgt tggatcacat ctgctacact tcctgatgaa
    17161 ctaagtgctg tacttaatcc actggcattg ttcagctgga atgtcttata gacgacgggt
    17221 ttacgtaaat ctgcatcgac tagtagaact cgttgacctg atttagcaaa aacgactgca
    17281 atgtttgctg cagtggtgga tttcccttct ccaggacctg atgaagtcac aacaatcgtt
    17341 ttgatttgct gaccagctgc ggaggcaaac tggatattcg tccgaatcgt acgatattgt
    17401 tcagcgattg gtgaagaggg attggtgagt gtgaccaaac tgactgcatg agtttgggct
    17461 gctttttgtt tctgtgttcg tgccattttc tttcctccta gactcttgag cggcttctgc
    17521 gtgatggcgc tgttttatcg tttgtagctt ttggttgtgt ctgagctggt ccttttttac
    17581 ggataccagc attcaattct ttcgctgaca tttctggaac tgttcctaag attgggaatc
    17641 ctaatgtatc tgtcacatat ttttcatctt tcactgtccg atcgagtaat tccaataaga
    17701 atgccagacc tacacctacc atcattccta acattaagcc agtcattaaa ttcaatttat
    17761 tatttggcga aacaggtgtc gtattggcaa ctgcacctga aatgatcgag attttatcaa
    17821 cattcatcac atcttttgcg ttctcttgga aaacttgtga agttgtgtta gcgatctgtt
    17881 gagcagccac tgcattcgta cttattgcct gaatcgagaa catttgtgaa ttttctgcct
    17941 gattaactga gatggcatct ttgatttgtt cagcagtcat tttcacattg tcttctgttt
    18001 ctaaacgatc tttgacttca ttgagcacta aatcactgac gatcatatct ttatacgtat
    18061 tgatcatttg caggttcgta ttgacatcat tgacatttgc agtgtctgat tgtggcagtg
    18121 tcacgatcaa ttgtgcttgt gaactgtatt ttggtgtcaa gatgaaaaat gttacgattc
    18181 ctgagatggc caagccagca aacattgaga tgatgattat taccaagtgt ttgcgtaatg
    18241 tttcaaaaat ttctttcaag ctgattgtct cttccatttt ttctccactt tcctatttat
    18301 tctctagatt catttgatct tttaattctt ttttcacacg atcaagttct tgatcactga
    18361 ctttttgata ggagatatta tcttgcatga agccttctcc ttgcagctga tcttgcttaa
    18421 tcgtaccaaa tgcctcccga taatctaaag caattttttt catttcatca aagttcatgt
    18481 ctgttttcat attcgactct agagcattca aaacggattg atagttgctg acaccgttta
    18541 gactcaatac ttttttcgct acgccttcta cgatctttct ttggcgccct tgtctaccgt
    18601 aatcaccatt tgggtcttca taacgcatac gagaataaga taatgcctga tccccgttca
    18661 atgtaatttt accgattgga aagtcatagc catcttgtga gaaagtgagg tcattattga
    18721 cttcgatacc accaactgca tcaacgagtt cctttagccc tttcatattg atagagacat
    18781 agtgatcgat tgggatgtct acatattttt gtacggtatc catcgccatg gcagctccgc
    18841 cgaatgcgta agcgtggttg atcttgtctt ttgtgtcacg acctacgatg tcgacatacg
    18901 tatcacgagg aatgctgacg atcgttgtct gtttgtcttc aggactgact gtggcaacca
    18961 tcatcgtatc tgatcttcct tgatcgaccc gacctaaatc tccagtatca atccccatca
    19021 atagaacaga gaaagattct tgtttgtcca gatcaactgg tttcgttcgt tctccttggg
    19081 ttcgttccac tgattcgtaa gttttctcaa tagaatgtga gagatccaga tataattttg
    19141 ctcctactcc tacaattgct aatactaata cgataagaac tgctaaaata atcagaaata
    19201 tttttttccc tcttgatttt cttcttcgtc ttgccatagt ttcctccgtt tgctaacctt
    19261 gcttgaatca acgttttaac tgtcaatagc ttatattgct atagcccatt tgctcagcaa
    19321 cagtttgtgc ttttgttgcg tatgctgcgc ttattttttc attccggatc tgctctattt
    19381 gactgagcac cgtcaaatat tgatcgtaag tagcggtggc agtcacttga ccatccttta
    19441 acatcgtatc gaataactga tctagttgcg tgacttgcgc gatctgaata tcagcgaatc
    19501 ctagatattg cataacaacc gttttccaag gactatcttt aaaaaagctc atattttcac
    19561 gtacacgagc gacatctgca cttgtcacct tttctttgat gatgacatcg tctacagctt
    19621 gctgccagtt tgatacattt ttagtaaata aatcgttgac agctgtctgg atcttcagtt
    19681 ttgattctgc actatctaac tgtgtcacga ttgctttctt ctcatcttgg attgcaacag
    19741 cttctttagg caattctgat tctttgatgt cgtaatcatc tgctgaaagt ttgacagagg
    19801 atagcttatt tgacaaactt gtgattgttt cttctgttat ttcagggttt agaaaaattt
    19861 tttcttttgt actatacagc ttgtctactt cttttgataa agaagtcaag gtgtcttttt
    19921 gattggtgat ggcagattct gcataattga tccgttgctg atgttgccgc tgattattga
    19981 tatggtatcc aaacaaacag atcgcaatag cacctgcacc taccgccaca gcagtcaatg
    20041 acttgacgaa tggcttttcc atagattcac tcctaagtat tgatgataga taaattaaga
    20101 tataattcac ttacataaaa atgacagctt tttatttaaa aaaacataat taaactaata
    20161 tattcacaga aatatttgta aacaagtttt ccctatataa tcatac
//
LOCUS       DASHWW010000049        20183 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.049, whole genome shotgun sequence.
ACCESSION   DASHWW010000049 DASHWW010000000
VERSION     DASHWW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.049"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            210..1016
                     /gene="proB"
                     /locus_tag="U2R64_001954"
     CDS             210..1016
                     /gene="proB"
                     /locus_tag="U2R64_001954"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEM8918755.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1013..2260
                     /locus_tag="U2R64_001955"
     CDS             1013..2260
                     /locus_tag="U2R64_001955"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEM8918756.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2336..2680
                     /locus_tag="U2R64_001956"
     CDS             2336..2680
                     /locus_tag="U2R64_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918757.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2797..3123)
                     /locus_tag="U2R64_001957"
     CDS             complement(2797..3123)
                     /locus_tag="U2R64_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918758.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3496..4698)
                     /locus_tag="U2R64_001958"
     CDS             complement(3496..4698)
                     /locus_tag="U2R64_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8918759.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4815..5330
                     /locus_tag="U2R64_001959"
     CDS             4815..5330
                     /locus_tag="U2R64_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8918760.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5529..5975)
                     /locus_tag="U2R64_001960"
     CDS             complement(5529..5975)
                     /locus_tag="U2R64_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEM8918761.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6022..7500)
                     /gene="msr(C)"
                     /locus_tag="U2R64_001961"
     CDS             complement(6022..7500)
                     /gene="msr(C)"
                     /locus_tag="U2R64_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEM8918762.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7854..8483)
                     /locus_tag="U2R64_001962"
     CDS             complement(7854..8483)
                     /locus_tag="U2R64_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEM8918763.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8467..8931)
                     /locus_tag="U2R64_001963"
     CDS             complement(8467..8931)
                     /locus_tag="U2R64_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8918764.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9418..10686)
                     /locus_tag="U2R64_001964"
     CDS             complement(9418..10686)
                     /locus_tag="U2R64_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEM8918765.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10917..11654)
                     /locus_tag="U2R64_001965"
     CDS             complement(10917..11654)
                     /locus_tag="U2R64_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8918766.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11721..12290)
                     /locus_tag="U2R64_001966"
     CDS             complement(11721..12290)
                     /locus_tag="U2R64_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEM8918767.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12418..13290
                     /locus_tag="U2R64_001967"
     CDS             12418..13290
                     /locus_tag="U2R64_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8918768.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13632..14504
                     /locus_tag="U2R64_001968"
     CDS             13632..14504
                     /locus_tag="U2R64_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8918769.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14501..16459
                     /locus_tag="U2R64_001969"
     CDS             14501..16459
                     /locus_tag="U2R64_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8918770.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16710..17561)
                     /locus_tag="U2R64_001970"
     CDS             complement(16710..17561)
                     /locus_tag="U2R64_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8918771.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17684..18151
                     /locus_tag="U2R64_001971"
     CDS             17684..18151
                     /locus_tag="U2R64_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEM8918772.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18414..18896)
                     /locus_tag="U2R64_001972"
     CDS             complement(18414..18896)
                     /locus_tag="U2R64_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEM8918773.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18996..19859)
                     /locus_tag="U2R64_001973"
     CDS             complement(18996..19859)
                     /locus_tag="U2R64_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEM8918774.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6067 a         4157 c         3664 g         6295 t
ORIGIN      
        1 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
       61 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tgcaagttgt
      121 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
      181 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
      241 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
      301 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
      361 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
      421 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
      481 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
      541 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
      601 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
      661 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
      721 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
      781 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
      841 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
      901 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
      961 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
     1021 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
     1081 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
     1141 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
     1201 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
     1261 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
     1321 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg accggcatca tttacgaatc
     1381 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
     1441 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
     1501 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
     1561 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
     1621 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
     1681 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
     1741 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
     1801 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
     1861 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
     1921 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
     1981 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
     2041 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
     2101 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
     2161 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
     2221 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
     2281 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
     2341 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
     2401 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
     2461 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
     2521 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
     2581 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
     2641 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
     2701 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
     2761 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
     2821 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
     2881 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
     2941 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
     3001 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
     3061 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
     3121 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
     3181 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
     3241 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
     3301 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
     3361 acctcttggt aaacggcgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3421 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3481 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3541 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3601 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3661 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3721 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     3781 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     3841 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     3901 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     3961 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4021 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4081 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4141 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4201 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4261 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4321 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4381 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4441 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4501 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4561 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4621 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4681 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4741 taaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     4801 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     4861 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     4921 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     4981 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5041 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5101 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5161 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5221 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5281 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5341 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5401 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5461 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5521 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5581 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5641 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5701 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     5761 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     5821 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     5881 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     5941 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6001 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6061 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6121 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6181 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6241 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6301 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6361 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6421 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6481 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6541 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6601 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6661 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6721 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     6781 cggtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     6841 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     6901 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     6961 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7021 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7081 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7141 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7201 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7261 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7321 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7381 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7441 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7501 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7561 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7621 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7681 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7741 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     7801 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     7861 aacgtagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     7921 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     7981 aactgatctg cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8041 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8101 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8161 ggcatcttcc ctgattcgta agcttggtta tagatttctt cgccatattc gtaacattgc
     8221 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8281 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8341 tgcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8401 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8461 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8521 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8581 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct cgattttctt
     8641 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8701 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     8761 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     8821 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     8881 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     8941 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9001 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9061 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9121 tattgattct tatcaaacta tagaagatag ctcttctgca gtagaaaatt ttacaccgcc
     9181 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9241 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9301 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9361 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9421 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9481 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9541 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9601 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9661 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9721 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
     9781 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
     9841 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
     9901 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
     9961 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10021 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10081 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10141 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10201 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10261 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10321 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10381 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10441 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10501 aattgtattt tctgagacag tagctgactg caaagtactc tctgtatcgt tttcaattcc
    10561 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10621 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10681 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10741 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttga tgaatttgct
    10801 ttttctacat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    10861 ggtcgtttga ataactattt aacaagtaat tctctttgga tattatccgt tatggattat
    10921 acttcctgtg tcgtcggacg gataatcatg ttactgacag acatccggtc tggcgtttct
    10981 atcgcaaatg ctacagcaga agctatatct tcggaggtca atccccattc tttttgcgct
    11041 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11101 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11161 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11221 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11281 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11341 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11401 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11461 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11521 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11581 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11641 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11701 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    11761 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    11821 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    11881 tttttcttga tgtggattgg ctttactgac aagcctcttc gttcttttgg atcggttaga
    11941 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12001 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12061 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12121 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12181 gctgctaaag gctcttcgtt ttcagcttgg atctgatgga tcacttcaaa gagcggatcc
    12241 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12301 ccttttatcc ttactttata acggacggct tatcatgtct aatacttata aaacatactt
    12361 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12421 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12481 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12541 gaacttggtg tgacactttt cactcggggc tcccgagaga tacagttgac ggattctggt
    12601 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12661 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12721 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    12781 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    12841 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    12901 caagatcgtt ggggactttt gatacatcga aatcatcctt tagcaaagca aaccgtcatc
    12961 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13021 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13081 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13141 gggatcatca atacttatgg gacggaaaaa atattcatcc cactcgatcc gccattacaa
    13201 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13261 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13321 ttaacaacga ataagataag caaaagatcc aacgattaaa taacacaagt ttcttaattt
    13381 atttcttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13441 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13501 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13561 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13621 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13681 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13741 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    13801 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    13861 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    13921 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    13981 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14041 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14101 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14161 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14221 cattttcact gaattattca agactggtga atcatttacg actacttcta caacgaaccc
    14281 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14341 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14401 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14461 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14521 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14581 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14641 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14701 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    14761 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    14821 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    14881 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    14941 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15001 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15061 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15121 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15181 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15241 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15301 aaacaaagca aaaacagctt ccttgatgct agcagcagct tttgcttcat tctttactgg
    15361 tgtgacagaa ccacttgaat tttcatttat gttcgttgct tggccattat atgtcttgca
    15421 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15481 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15541 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15601 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15661 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15721 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    15781 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    15841 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    15901 cgttgcagat gagatggcaa aactacatgg tggtgctgca gcacgacctg cacaaacaaa
    15961 caccgtggtt aaaacagaaa catttgccgg tgaaacgatc gaacaagata tttacgctat
    16021 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16081 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16141 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16201 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16261 atatgtagaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16321 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16381 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16441 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16501 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16561 caactccgcg gtaataagtc cagctaaacg aaacatatga agagctattt tttatttgac
    16621 tcttcttatt acttgatgca gaacagcttt ttcacaaaat ttttcttcat actcaaaact
    16681 aatcggcttt ttcacaacct ctttatacat tattcctgat ccaatatttc ttttaatgct
    16741 gcttcaagag aagttaatgg ttttcccaat actttttcta aatcatcaga ggaaatagct
    16801 aactgatcct ttttaatatc atgttggatc gctaaaaaca tgtcagctgc ttcttgaggg
    16861 aatccggctt cttttagatt ttcgacaaac gctgcatcac ttgcttcaat aatttctaac
    16921 tctttacctg tcgcacgctc taatgccttg gctaattctt catagtcagt tagattgccg
    16981 gataattcta agatttctgg agagtcactt tctactagta cttttgctgc agcttctgca
    17041 tattcacgtt tcaatgccca acctgttttt ccatttcctg cagcataaac gaattgacca
    17101 gtttttaaag cctgcccaat gataggtaat tcattctcta cataccaatt attccgtaaa
    17161 aatgtatggg aaatacctga atccttaatc attttttcag tgaattggtg atctggcgct
    17221 aatacactga tcgagtgatc ggcatctgca aaacttgtat aagcgatata agatacccca
    17281 gctgcttgtg ctgccttcac tacattctta tgttcggctt gacgatttcc tggaacgcca
    17341 gagacaaaaa gcaatcgatc tattcctttc aacgcttctt tcattgagtc taaatcatca
    17401 taatcaccaa tacgtatatt aaatccagct tctttcagtg cttctccttt ttcttcacta
    17461 cgtactagta catagatttc attttgtgga accatctttt ttaagaattc cagcgcataa
    17521 ccaccaaaac ctccagttgc tcctgttact aaataatgca tatttgccac tccctattct
    17581 ttttatttgt taagatttac agctgtacat ttataaatta cacctttatc ataaagagtg
    17641 tggtaagata agtcaagcaa aaaaaatgaa aggatgacaa ctgatgaagt attctctgca
    17701 atttagtgat gcaatccatg tacttgccta tattgaaatg tttcaagata cccgatcact
    17761 ttctagtgag atgattgcca gtagtatcga aacaaatgca gcaaatgtac gtaaaatcat
    17821 gagtcagctc aaaaaatccg gtttgatctt tacaaaaacc ggaaaaccgc agccttccct
    17881 tgccaaaagt ccagatcaga tttctttact agatgtctat cgcagcatcg aaggtaatac
    17941 acagcttatc caagtcgatc caaaaacaaa tccaaattgc gtcgttggtg cgaatatcca
    18001 agaagcttta gaagaaagct acgctcggct gcagaaaaag gcagaagaag aaatggctaa
    18061 gatcacactt gatagtctga tacataaaat agccgttttg gaaaaagaaa aaagaccaga
    18121 aaacacaggc ctcgtagaga gatttttata attctctcta ctgtgcctgc atttttctga
    18181 tcggaatcgt ctacataaat tcttttattc tccgggggac aaaagccttg tcatgcccct
    18241 ttttcctctc taatgctcag gtcaaagcgc tgaagtcatg acgtcttgat aaacggtgtt
    18301 caagtagctg accctcggca ttagttctga aaaatgcaaa atatggaaag ctatttccca
    18361 tttttcctct ctaatgctca ggtcaaagcg ctactttcac gacctctata ttatcatggt
    18421 ttattgacta ccggtatcca gatttctccc atatatttcc cgttggtaac tcccatttcg
    18481 actacagcat ttggaccccc aacataggcg taatcttcta cttctcttaa aacatgccca
    18541 aaggccgtat tcgtcaaatc atttcttaat tcttcaggcg attctgctaa agcgcttaca
    18601 acaagatacg ttccttttgg gaatgggatg attcgcgtag tgtttggaac atcctgactc
    18661 gtttgaacac cgacatagta catcattttc ccgttatagg gttcgttgac tgtaaagaaa
    18721 taatgatttt cagcagcttg tttcaatgca tctattgttc cattaccgat aactttttgc
    18781 tcaaatgctt gtttctctgc agccaaaccg acaaaatccg tattgctact cttcaattcc
    18841 acaccaatac ccgtcaccgt aaaatctggt ttttcttcga tcctatactt tgccatttct
    18901 cccacccttt ctattatatt aagttcatct tacataaaat taaagggaaa tgacacgatt
    18961 acgctctttt ttctagggat atttttattt tttaactatt tttttgcttt cactgcaatc
    19021 caaatctcac tgtaaacatt actgaaatcc tctccccatt ttgtaaaaga gatctcggga
    19081 gcttcgacta acccataatc tgaagaagga agccattctg catagatttt cccccaagta
    19141 tcttgtaaag tttggggaaa tggcccttta ttaggaaaaa tggcccaagt gtgttcttct
    19201 atagcaagca tttctaaatc agcgtacgga ttttcttttg tcgtagcaaa gccaatcatg
    19261 tgcatcaaac tgcccttttc ttccaagcgg tctccatcaa atccataaga aacgttgatt
    19321 acttgatttg gatataaatc tcctaactta tgcatctctt ccctttgagt ctccgtgatc
    19381 gtctgcgcta acttttgtat ttcttgattg actccttcaa atttgacagg aacttttttc
    19441 gccacacctg ccacataaaa ctgttctttc ttttcgatac gaaattccat cgattttcct
    19501 cctctgacat caataaaaaa tgtcaagcgt ggaaaagatt tttgtatgcc gtatctgctg
    19561 atttctgaag gcagatatcc tgaccaatca cgaaaagctc ttgaaaaacc ttcgactgtt
    19621 tcatatccat atctaaacgc cgtttctgtc actcttgatc catctagaag atcgcgatta
    19681 gccaaagcca atctacggtt tttgatatag tccattagcg acatccctgc aataaacgta
    19741 aagatgcgtt ttaattgata ttcagagatt cctgtatttt cggctattat tttataggaa
    19801 agtccttctg tcaaatgttc ttcgatgtaa tcgatcaatt ggttcagatc tttaagcata
    19861 tttatcttcc tccttgattg cctttttatc atattatcaa agaaagtcaa ttacttgatg
    19921 aatcaggaac caatttagtc agatgtagaa aatgttgtat ggatctaaag aaaattctca
    19981 agcagcgttt cgtaacggat aattggtatt atctgcctat ctatgtttta cctttagaaa
    20041 aataaatttt ggggaagaca gattctaagt aaacaaagcg gtaaaaatat cttttattcc
    20101 cttagttaat ccgcttacta cctactgtac aaagcaaatt gttgttcaaa ctgctgatca
    20161 gaacgctgct tggatttttc ttt
//
LOCUS       DASHWW010000050        19996 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.050, whole genome shotgun sequence.
ACCESSION   DASHWW010000050 DASHWW010000000
VERSION     DASHWW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.050"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            4..816
                     /locus_tag="U2R64_001974"
     CDS             4..816
                     /locus_tag="U2R64_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEM8918775.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="U2R64_001975"
     CDS             813..1613
                     /locus_tag="U2R64_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEM8918776.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="U2R64_001976"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="U2R64_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEM8918777.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="U2R64_001977"
     CDS             3110..4819
                     /locus_tag="U2R64_001977"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEM8918778.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9383
                     /locus_tag="U2R64_001978"
     CDS             5031..9383
                     /locus_tag="U2R64_001978"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEM8918779.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9527..10000
                     /gene="rimP"
                     /locus_tag="U2R64_001979"
     CDS             9527..10000
                     /gene="rimP"
                     /locus_tag="U2R64_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEM8918780.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10024..11199
                     /gene="nusA"
                     /locus_tag="U2R64_001980"
     CDS             10024..11199
                     /gene="nusA"
                     /locus_tag="U2R64_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEM8918781.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNSKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11221..11514
                     /locus_tag="U2R64_001981"
     CDS             11221..11514
                     /locus_tag="U2R64_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEM8918782.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11511..11822
                     /locus_tag="U2R64_001982"
     CDS             11511..11822
                     /locus_tag="U2R64_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEM8918783.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11835..14141
                     /gene="infB"
                     /locus_tag="U2R64_001983"
     CDS             11835..14141
                     /gene="infB"
                     /locus_tag="U2R64_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEM8918784.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14168..14515
                     /gene="rbfA"
                     /locus_tag="U2R64_001984"
     CDS             14168..14515
                     /gene="rbfA"
                     /locus_tag="U2R64_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEM8918785.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14623..14844)
                     /locus_tag="U2R64_001985"
     CDS             complement(14623..14844)
                     /locus_tag="U2R64_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8918786.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            15292..17655
                     /locus_tag="U2R64_001986"
     CDS             15292..17655
                     /locus_tag="U2R64_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HEM8918787.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKLGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRNDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFHSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAATLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            18023..18946
                     /gene="truB"
                     /locus_tag="U2R64_001987"
     CDS             18023..18946
                     /gene="truB"
                     /locus_tag="U2R64_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEM8918788.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18950..19891
                     /gene="ribF"
                     /locus_tag="U2R64_001988"
     CDS             18950..19891
                     /gene="ribF"
                     /locus_tag="U2R64_001988"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HEM8918789.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKKDEQATAEYFSQQ"
BASE COUNT         6862 a         3513 c         4389 g         5232 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgtgtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccagctagga cgaaatattc
     5701 cagccgatga accaacgaca ccaatgatca gtatcgttga agaagaacga agagtcacac
     5761 ttgaggggta cgtattcgac aaagaagtca gagaactacg ttcaaaacgc aagatcttga
     5821 ctttgaaaat cacagattat acttcatcat ttatcgtcaa aaaattctcg aacggcgaaa
     5881 aagatgaaca agtatttgat gcgatcagtg tcggtagctg gttaaaggta cgaggaagta
     5941 ttcaagaaga tacgtttgtc cgtgatttgg tcatgaatgc gcaagatatc atagaagtca
     6001 aacatacacc tcgcaaagat tatgctcctg aaggggaaaa acgagtagag cttcatgttc
     6061 atagcaatat gagtacgatg gatgcaacaa acagcatctc tgatcttgtg gcacaagcag
     6121 gaaaatgggg acaccgagct atcgccatta cagaccatgg tggtgcgcaa gcctttccgg
     6181 aagcacatag tgctggaaaa aaagcaggtg tgaaaatctt atacggcgtg gaagcgaatg
     6241 tcgtagatga tggtgtccca attgcttata atgatgcaca tgaagcattg agtgaagcca
     6301 catacgtcgt atttgacgtg gaaacgacag gattgtctgc agtatatgac acgatcatcg
     6361 agctagccgc agtcaaaatg tataaaggaa atgtgatcga aagctttgat gaatttatcg
     6421 atccaggaca tccattgtca cgaacaacgg tagatctgac tggtatcacg gatgaaatgg
     6481 ttcgagggtc aaagtcggaa gaagaagtat tgcggatgtt ccttgaattt tcaaaagata
     6541 caattttggt agcccacaac gcggcttttg atatggggtt cttgaatact agctacgcaa
     6601 ggtatggtat tcctgaagcg gccaatccag tcattgatac gttggaatta gctagatatc
     6661 tgtatcctca attcaaacgt ttcggattag gtgtgttatc taaaaagttt ggtgttagct
     6721 tggaacagca tcaccgagca atctatgatg ctgaagcaac tggtcactta gcatggatct
     6781 ttgtgaaaga ggcaatggac aatcataaca tgctttatca tgatcagcta aatgagcata
     6841 tcggagaagg agattcttac aaaagggctc gacctttcca tgtaacgatt ttagcaaaaa
     6901 atcaggcagg actgaaagat ttgttcaaac tgatttcaat gtcgaatgtc gaatacttcg
     6961 aacgcgtccc acgaatacca cgctcccaat tgaaaaagat gcgtgaaaat ctattgatcg
     7021 gctcagcttg tgataaggga gaaatattcg aagccatgat gcaaaaaggg gtagaagagg
     7081 caagaaaccg agcaaaattc tatgattata ttgaagttat gccaaaagcg gtctatgcgc
     7141 ctttgatcga gcaagaattg gtaaaaaatg aacatgattt ggaagaaatt atccaaaatt
     7201 tggtagaaat cggaaaaagt ttggataaaa tcgttgttgc aacaggtaat gtacattatc
     7261 tgaacgaaga agatgccatt taccgaaaaa ttttgatcaa ttctatgggc ggagcgaatc
     7321 cgttgaatcg tcatagtttg ccggatgtcc atttccgaac aaccgatgag atgctaactg
     7381 catttcactt tttaggggaa gaaacagcga aagagatcgt agtagaaaat acgaataaaa
     7441 tcgcagatat ctgcgaagaa gtgattccag tcaaagatga actttataca ccgaagattc
     7501 caggttcaga agatgaaata tcagaattga gttacacaaa agcaaaacaa atgtacggag
     7561 atccgttacc tgagatcatt caaaaacgat tagaaaaaga gttgaattct attaatggta
     7621 atggcttctc ggttatttat ctgatcgccc aaaaactagt gcataaaagt aatgaagatg
     7681 gctatctagt aggttcacgt ggctctgttg gctctagctt tgttgcgacg atgacaggaa
     7741 tcactgaagt taatccatta gcccctcatt attattgtcc agagtgccaa tattccgagt
     7801 tttttgaaga tggtacgtat ggttctggat ttgacatgcc agaaaaacaa tgtccaaaat
     7861 gtggtgcacg cttaaacaaa gacggtcatg atattccatt tgagacattt ttaggattcc
     7921 atggagacaa agtgcccgat attgatttga acttctcagg tgattatcaa gcagaagccc
     7981 ataactatac gaaagtattg tttggcgaag actatgttta ccgtgccgga acgattggta
     8041 cagtcgccga caaaacagca tatggctatg taaaaggata cgaaagggac aataatctgc
     8101 agtttcgaag tgcagaagtc gacagattag caaaaggcgc tactggagtc aaacggacaa
     8161 ccggccagca tccagggggg atcatcgtta ttcccgatta tatggatgtc tatgatttta
     8221 cgccgatcca atatccagca gacgatcaaa attcagaatg gaaaacgact cattttgatt
     8281 tccactcgat tcacgataat gtattgaaat tagatattct agggcatgat gacccaactg
     8341 ttattcggat gcttcaagat ttatcaggga tcgacccaca aacgatccct acggatgacc
     8401 cggaagtgat gcggatattt gccggtcctg aagtacttgg agtaagtcag gaacaaattt
     8461 attccaaaac agggacatta ggtattccag aattcggcac tcgttttgtt cgagggatgt
     8521 tagaagaaac gcatcctaca acttttgcag aactactgca aatttccgga ctatctcatg
     8581 gtacagacgt atggttagga aatgcggaag aattgattcg acgaggagat gcgacactgg
     8641 cggaagtaat cggctgtcgt gatgatatta tggtttattt gatccatgct ggattagata
     8701 gcgggatggc atttaaaatc atggaaactg ttcgtaaagg acaatggaac aagatccctg
     8761 atgaattgcg agaaacctat ctatcggcga tgaaagaaaa taatgtgccc gactggtata
     8821 tcgattcttg ttcaaaaatc aaatatatgt ttccgaaagc ccatgctgca gcttacgtat
     8881 tgatggctct tcgtgtcgct tatttcaagg tttatttccc tattttgtat tactgtgcat
     8941 acttttctgt acgtgcagac gactttgatc tagtctccat gtgcaaagga aaagatgctg
     9001 tgaaacaagc aatgaaagaa atcacggaca agggattaga tgcttccgta aaagaaaaga
     9061 atcaactgac agtgctggag ttagccaatg aaatgctgga acgaggattc aaatttggaa
     9121 tgattgattt gtataaatcg gatgccgtta actttgttat tgaaggtgat acgttgatcg
     9181 caccatttag agctgtccca agtttgggaa ccaacgtggc gaaacaaatc gttgaagcaa
     9241 gaaaagacgg tccattttta tccaaagaag atcttgccac ccgcggtaaa gtttcaaaaa
     9301 cattgatcga atatatgaac gacaatggcg tattgaaaga tctaccagat gaaaatcaat
     9361 tatcgttatt cgatatgcta taagcatctg ttttcctgtc tgcttgtaat tttaagcaga
     9421 gtatggtata gttcttatag gtaatgatac taactgtgag tgagcggatt tttcgctcac
     9481 tctttttaat ggaattacgc acttaatttt taaggaggcg aaacttttga gtagcgtcgt
     9541 tgaaacagtc acagaaatgg tgacaccgat tttagatgaa caaaattttg aacttgtcga
     9601 agtcgaattt gtaaaagaag gaaaaagctg gttcttacga gtatttattg acaaagaagg
     9661 cggtatcgat atcgaagaat gcgcctttgt cagtgagaaa ctgagtgaaa aacttgatgc
     9721 agcagatcca gatccgattc ctcaagctta tttcctggag gtatcctccc cgggagcaga
     9781 gcggccattg aaaaaagaaa gcgactatga aaaggcactt ggtgattatg tccatgtctc
     9841 cttataccaa ccagtagatg gcgaaaaaca atatgaagga tttcttcaat catttgatgc
     9901 tgaacagctt acattgaaaa tacgcataaa aacacgagaa aaagaattga cttttgaccg
     9961 aaaaaatatt gcaaaagctc gcttagctat ccaattttaa tcacggagag gaatcagaaa
    10021 aaaatgagta aagaaatgtt aaatgcgtta gacgctttag aagctgaaaa agggatctca
    10081 aaagaaatcg tgatcgatgc attagaagca gcattggttt ctgcatacaa acgtcactat
    10141 ggccaagcac aaaacgtcga agtggaattt gatcagaaaa aaggaaagat ccatgtctat
    10201 gcggtaaaag aagtaacgga agaagtgatg gattcacagt tggaagtctc attgaaagat
    10261 gcacttttaa tcaatccagc atatgagatc ggtgatacga tccgttttga agtaacacca
    10321 aaagattttg gacggatcgc tgcgcaaacg gctaaacaag ttattttaca gcgtgtacgt
    10381 gaagcagaaa gaacgattat ttataacgaa ttcagtgctt atgaaaaaga catcatgcaa
    10441 ggaatcgtcg aacgccagga taaacgttat atttatgtca atcttggtaa aattgaggca
    10501 gttctttcta aacaagatca aatgccaaat gaattttatc aaccacatga tcgaatcaaa
    10561 gtttatgttt cccgagtaga aaatacgtct aaaggtccgc aagtatttgt tagccgcagc
    10621 catccagacc tattgcgtcg cttatttgaa caagaagtac cagaagtcta tgatggaatc
    10681 gttgaaattg tcagcatcgc ccgtgaagct ggcgatcgtt caaaagtggc agttcgctca
    10741 aatgatccaa atatcgatgc agtcggtaca tgtgtcgggc caaagggaca acgagttcaa
    10801 gcaatcgtca atgaattaaa aggcgaaaac atggatatcg tcgaatggaa tgaagatcca
    10861 gctgtattca tcgcaaatgc attgaatcct gcacaagtca tggatgtgat cttcgatgag
    10921 acaaattcaa aggcctgcac agttgtcgtt ccagactacc aattatcgct agcaatcggt
    10981 aaacgcggac aaaatgcacg tttagctgct aaattgacta accataaaat cgatatcaaa
    11041 tcagaatctg acatgacgga attttatgaa aatcaagaac aacaaaaaga aacagaagaa
    11101 ctgcatgatg aagcaatcgt tcagtcagat ttaacagacg atgaatatga aacaattgca
    11161 ttcaacaatg aaacggtcga agaaaaacca gaagcttaac tttagtaagg aggcaaagag
    11221 atgaaacaaa ggaaaattcc tttacgcaaa tccgtggttt caggtgaaat gaaacctaaa
    11281 aaagagatgg tccgaatcac ccgttcaaaa gaaggggaag tatcgatcga tccaactgga
    11341 aaaatgcctg gacgaggagc gtatgtctca cttgagccgg aagaagtaca acaagcttgg
    11401 gataaaaaaa ttctcgatcg agtactcgaa acaacattaa cagatgagtt ttatcaagaa
    11461 cttcttgact atgtcactca ccaaaaagca cgtaaagagt tatttggaaa atgaatacag
    11521 ttaatcggca aaaagccatg aatctcatcg gtctagcgat gcgcgcggga aaactaatca
    11581 cgggtgaaga actgaccatt gctgaaatcc gcaaacaaaa agcaaaattg gtgtttgtgg
    11641 caaccgatgc aagtgagaat acaagaaaaa agataaaaga taagagttca tattatgaag
    11701 ttccttgctt tgagctattt tctgaagcag aaatcacgca gatgatcgga aaacctcgca
    11761 aggtattcgg aataatggat gccggatttg cgaagaagac caaggagcta attgaaggtt
    11821 aggaaggtga ttgcatgggc aacaaaagaa tctatgaatt agcaaaagaa ctcaaaaaat
    11881 ctagtaaaga cgtcgtggaa aaagcacaac aacttggcat cgatgtgaaa aaccatatgg
    11941 gtgcgattac tagcagtgat gagaagaaat tgcaacaagc gttcaaaaac ccaagcacga
    12001 aacaacaagc tgcacaacaa gcaagcagaa aaccagccaa tcaacagccg aacgatcaac
    12061 gtaaaaaaga aacaacgaac aatcaacaaa aaaataaaaa taaccgcagt tatcaagatc
    12121 gcggtcaagg gagcggtcaa gtgaatcaag gaaaaaaacc aacaacaaac caaaataata
    12181 cgggaaatac cagcagccaa aatcgtcaag gaacgagcca aggcggcaat caaaaccgta
    12241 ctaacaataa caacaaacca aacaataaca atcgcggcaa atttaataat aataaccgta
    12301 atcgttataa taaaaaaggt aaaaaaggca aacagcaaca atcaactaaa ccagctgtac
    12361 caccacgcaa attccgtgaa ttgccagatg tattagagta tactgaaggt atgaacgtag
    12421 cagatattgc gaaaaaaatt catcgtgagc cagcagaaat cattaaaaaa ttatttatgc
    12481 ttggtgtcat ggtcaatcaa aaccaagcac tggataaaga tacgattgaa ctgttagcga
    12541 cggactatgg catggaacca caagaaaaag tccaagttga cattgctgat atcgataaat
    12601 tcttcgaggc agaagaagtc gatccagata aattagtctc acgtccgcca gtagtaacga
    12661 ttatgggaca cgtagaccac gggaaaacaa ccttattgga tacattgcgc cattcacgtg
    12721 taacaagcgg cgaagccggc ggaatcacac agcatatcgg tgcctaccag atcgatattg
    12781 atggtaaacc aatcactttc ttggatacac caggacatgc ggcctttaca agtatgcgtg
    12841 cacgtggagc aagtatcaca gatatcacga tcttagttgt tgctgcagat gatggcgtca
    12901 tgccacaaac agttgaagca atcaaccatg ccaaagctgc aggcgttcca atcatcgtcg
    12961 ctgtaaataa aattgataaa ccaggtgcaa atcctcagca tgttatgcaa gaattaagtg
    13021 agtatgaatt aattcctgaa gcatggggtg gagaaacgat ttttgttgag atctcagcga
    13081 aattcggcca aaacatcgaa gaattgctgg aaatgatcct gttagtcgca gaagtagaag
    13141 atttaaaagc agatccaaca caacgcgcaa tcggaacagt gatcgaagca cgtcttgata
    13201 aaggtaaagg tcctgtgtca accttacttg tccaagaagg aacacttcac gttggtgacc
    13261 caatcgttgt cggtaatact tacggacgtg tccgtgtaat gacaaacgat cttggccgtc
    13321 gcgataaaga agcaggacct gcaacgccag tagaaatcac tggcttgaat gatgtacctc
    13381 aagcaggtga ccgtttcgta gtcttcgaag acgaaaagac agcacgtgca gcgggtgaag
    13441 aacgcgcaaa acgtgcatta ttggaaaacc gtgctgccac aagccgtgtg actttggaca
    13501 acttatttga aagcctgaaa gaaggcgaat tgaaagaagt taacgtaatc atcaaagcag
    13561 atgtacaagg ttcagcagaa gcactggctg catcattgaa gaagattgat gtggaaggtg
    13621 tccgtgtaaa aatcgtccat tcagctgtcg gagcaatcaa tgaaagtgat gtaaccttag
    13681 cagcagccag caacgctatt atcatcggtt tcaacgttcg tcctacaccg caggcaaaag
    13741 tgcaagctga tactgaagaa gtcgatattc gtcttcaccg tatcatctat aaagccatcg
    13801 aagaaatcga aactgcgatg aaagggatgc tagaccctga atttgaagaa aaaatcaccg
    13861 gtcaaatgat cgttcgtgaa accttcaaag tttctaaagt tggtacgatt gcaggtgcct
    13921 atgtaacaga aggatatatt cgtagagata gcggtgtccg tgtaatccgt gacggaatcg
    13981 taatctatga aggccaactt gcaagtctga aacgattcaa agatgacgtg aaagaagtca
    14041 aaatgggtta tgaatgtggt gcgatgattg aaaaattcaa tgacatcaaa gtagatgacg
    14101 taattgaagg atttatcatg gaagaagtca aaaatgacta aaaactgata aaaggaggcc
    14161 aatcattatg gctaactacc gtgatcgccg agtcggtcaa gaaatcttaa aagaagtcaa
    14221 tgatattttg cgcaaaaagg tccgtgaccc tcgtgtggag aacgtaacga tcacagatgt
    14281 gaaagttacg ggggacttac agcaagcaac gatctattac agcattttat ctgacttagc
    14341 atcagataag aaaaaagcac aagatggatt gaataaagca tcaggattga ttcgtcgaga
    14401 gttagggcac aatctaagta tttataagac acctgaattg ttctttgaac ttgatgaatc
    14461 agttgtctat gggaaccata tcgatgaatt gcttcgcgac ttgaacaaag actaatcaaa
    14521 aaatcccgca aatcctgtga aatcaggggt tgcgggattt ttttgttttc attaagacgt
    14581 attacctaag agttccatga ctttagtctg gtagcgtgtc agctaaccaa aaaagagaaa
    14641 aagaaaagta aaaaattcga ctttcttttt tctatagtat ataaattttt gcatatagat
    14701 aaagatcaag ataccgataa cggaagctag attgtaatct attttagtga cagtcaggta
    14761 tagccaagta actagaagat cagtggaacc tgcaccataa aagtttgagt ttgtcggtcc
    14821 gttgacagtt aaaagaaaaa tcacgttgaa gttattgata tttccgatta cgccgcttcg
    14881 atttggtcac gatccaaatt ttggataatc cctgtagaaa ttagcatagt agctgggata
    14941 ccaattcaca tattgacaaa gataacagag acttttacat aaaacggatc aatcaggaaa
    15001 ggaattgctc gatccagccc cagttttcca acaatgtgtt aactggccta gcgtcattca
    15061 gcaaattatg catgatgagg agcgaaatga actgcggaac agccattgtg ataacgacaa
    15121 gttttttgga tcaatgtaaa aaacgtcagc gaaaggaaaa atttcgtggt tttttatacc
    15181 tgttcatttg gctagatata aaatccaaac aaatgaacag aagtgcttat taggtttcaa
    15241 ttgggagtat ctgcgctaga ataagagtaa taatgaaaag gagtgttatg tatggattat
    15301 tctagtaaag aatactttga taaaatgacg gcttggtggc gtgctgctaa ttatctttct
    15361 gttgggcaac tttatcttaa agataacccc ttactgagac gtacactgaa accagaagat
    15421 gtcaaaaaac atccaatcgg tcattgggga acgattcctg gccaaaattt tatttatgtc
    15481 catttgaacc gagtcatcaa taaatatgat ttgaacatgt tttatatcga agggccagga
    15541 cacggcggac aagtcatggt atcgaatgct tatttagatg gaagttacac agagatctat
    15601 ccagaagtaa cggaagatga gacaggaatg caaaaattat tcaagcgatt ttcatttcct
    15661 ggaggcattg cttctcatgc agcaccagaa acaccaggtt ctatccatga aggcggagag
    15721 cttggatact ctctttcaca tgcagtcgga gctgtattag acaatcctga agtaatctct
    15781 gctgtcgtga ttggtgatgg tgaagcagaa accggtcctt tagctggaag ctggttctca
    15841 aatgtcttta tcaatccagt gatagatgga gctgttttac cgatccttca tttaaatggt
    15901 gcaaaaatag ccaacccaac gatcttggca cgtaaatcag atggagaatt agcaaattac
    15961 tttaacggac ttggctggga gcctttcttt attgaaggaa atgatccaga aaaattaaat
    16021 cctgttatgg ctgaaaaaat ggatcaagca atcgagaaaa tcaaatccat ccaaaaagaa
    16081 gctcgcctga agacagcaac agatgtcgtg atgccaaaat ggccagtatt gatcgtacgc
    16141 acaccaaaag gatggaccgg tccaaaagaa tgggacgggg aaccaattga aggaaccttc
    16201 cgagcacacc aagtaccgat tcctgtagat caagaacata tggatcatgc agatgcttta
    16261 ctccgttggc tgaaatccta tgaaccagaa aaattatttg atgcacaagg acgtatttta
    16321 gaagaaatca gagaaattgc gcctactggt gaccaaagaa tggcaaaaaa tcctatcacc
    16381 aatggtggaa tcgatccaag accgcttatt atgccagatt ggaaaaaata tactttgcaa
    16441 tttgaaaaac taggctccgt taaagcagaa gatatgaccg aacttggtaa attcgttcgc
    16501 gagatcattg agaaaaatcc agaaaatttc cgtatatttg gaccagatga aacaaaatca
    16561 aaccgattga atcaagtttt caaaacgaca aatcgccaat ggatggaaaa aatcgaacca
    16621 gaaaatgatg aatggctttc gccatctggt cgcgtcatcg acagtcaatt atcggaacac
    16681 caagatgaag ggttcttaga agggtacgtt ctgactggac ggcatggttt ttttgcaagt
    16741 tacgaatcat tcttgcgagt ggttgactct atgttgactc agcacttcaa atggatacgg
    16801 aaatcacatg acctttcttg gcgaaatgat tatccttcgc taaatctcat tgcaagctca
    16861 acagtcttcc agcaagatca caatggatat agccaccaag atccaggaat attgacacat
    16921 ttggcagaaa agaaggcgga gttcatccgt gaatatctgc ctgcggatgc aaatacattg
    16981 ctcgcagtca tggataaagc attccactcg tcagaaaaaa tcaatttgat catctcttcc
    17041 aaacatccgc gtgctcaatt ttactcagca gaagaagcag ccgtcttagt gaatgaaggc
    17101 ttgaaaatca ttgattgggc ttcgacagca aaagaggagg aacctgaatt ggtcattgct
    17161 gctgcaggaa cggaatctaa cttagaagca ttagcagctg caactttgct gctggaagaa
    17221 ttcccaaaac taaaaattcg gttcattaat gtcgtagatt tattgaaatt acgtcatcca
    17281 agtcaagatc cgcgtgggtt gagcgatgaa gaatttgatc aatattttac aaaagacaaa
    17341 ccgatcttat ttgctttcca cggttatgaa acattggtcc gcacgatttt ctttgatcgt
    17401 cataaccatc atttaatgat tcatggctac aaagaaaatg gagatatcac gacaccattt
    17461 gacatgcgtg tagtaaatga acttgatcgt tatcatttgg caaaagacgc agctttaaaa
    17521 atcaaaggaa gtcaagcaga agattttgcg gaaaaaatgg atcagaaatt acaagaacat
    17581 caaaactata ttcgtgaaaa tggtattgat ctgccagaag tattggattg gaaatggaaa
    17641 aatcttgatc aataaaatga taaaatcgat cccgcaaaac agaatttttt acattgatta
    17701 agaaactgaa aaaataaata aaaaaaacgg aaaaaagact ggaagaatgg acagtctttt
    17761 ttttcgtttt tgggaagtga aaaccaaact atttacctgt aagccaccca taaatccaat
    17821 caaatggtgc aaagaaaaaa tcttccattc tattccctcc tttaaaaaaa cataacatga
    17881 tttctattta cgtgagcatg aattttgtta cgtttttatt gccgaaaaat aaaaaccgtt
    17941 cattatgatg tcaaattcgt cagtaattga tgcaatgtgt tataataatt cagttaaatc
    18001 aaaaatgaaa tggagaaaag acatggacgg gttattacct ttatggaaag aacgcggaat
    18061 gacaagtcat gattgcgtat tcaaattaag aaaaatctta catacgaaaa aaatcggaca
    18121 tgggggtacg cttgacccag acgtagacgg tgtgttgcct atttgtattg gaaaagccac
    18181 aaaagttatc gagtatttga cagattctgg gaaaatctat gtaggcgaga taactctagg
    18241 tttcagtaca acgacggaag atcgatccgg agaacgggta gaaacaaaac cagtagatat
    18301 gtctttatct gaagaaaaaa tagatgaagt gatggcttca tttattggtg agatcaccca
    18361 gataccacca atgtactcag cggtaaaagt caacggtaag cggttatatg aatatgcccg
    18421 caataatgaa acagtggagc gtcctgttag aaaggctcag atttaccgtt ttatccggac
    18481 aagtgaattg acaagagacg aagtgacagg aaccatttct tggcgcttcg aagtagaatg
    18541 cgggaaagga acctatgtcc gcacattagc tgtagataca ggcaagaaac ttggttaccc
    18601 tgcgcacatg tctgatctga cccgaacagc aagtgccggt atgtcccaga aagatgctct
    18661 gacattagaa gaagtagctc aagctgtgaa aaatgggaca atcgatgatt gtttgctgcc
    18721 aatagaaaaa ggagtgaaac gattcaaacg agtagatatt actgatgaag tatggcagaa
    18781 agtaaaaaac ggtatgagac ttgattatac tgtatttgcg ctcccagaaa tgccgtcaga
    18841 agaaattgct ttgttttata aaggcaaagt tgtcagtatc tatcagccaa acccgaaaga
    18901 aaaaaacaaa ttaaaaccta gtaaagtatt gagaaatgag gaataacgaa tgaatatcat
    18961 caagatcaga catccttacc aatcagaaca aattccagaa gacgatgtcg ttttagtact
    19021 gggatttttt gacggcgtgc atattggaca ccagaaagtc ataaagacag gtatggaaat
    19081 tgcacaaaaa gaaggattga aattagcatt gatgactttc aatcagcatc catcgattgt
    19141 ctttaaaaag atcgatccta gcagcgtgaa atatttgact agccttaagc aaaaagaaga
    19201 aaaaatggcc gctttgggta tagattattt atatgaagtt gattttactt cttcttttgc
    19261 tcatttagca ccgcaggaat ttgttgatca atacatcgta gggttacatg caaaatatgc
    19321 tgtttccggt tttgattata cgtatggacc aaaagacatt gcagatgtcg ctcattttcc
    19381 tgaatatgcc aaaggaagat tcaaaatcgt cacagtttct aaagaagaag aacaaggtga
    19441 aaaaatcagc tctacccgta ttcgaggatt actagacagc ggacaagtaa aagaagcagc
    19501 aaaactatta ggttgcacat atgaggtaga aggggtagtt gtccatggcg atgcacgagg
    19561 cagactacta ggattcccta cagcaaatgt caaagtaaag agcacagttc atttgcctaa
    19621 agaaggtgtt tatgtatcgg aaataaaaat tggggaaact tggtatccag ccatgggttc
    19681 aattggacat aatgatacat tcggtgaagg acgggagctg actgtagaat tgtatatttt
    19741 ggactttaat caagatatct atggtgaaca tgtcgcagta cgctggaatc aatttttaag
    19801 agatcaagtg aaattttcta gtgtagagga attgattgaa caactcaaaa aggatgaaca
    19861 agcaacagct gaatattttt ctcagcaata aaacattatg cataaaatct cttgtttatg
    19921 tataactagc aatttcaata aaatgggtga taaataagcc caggaaaggg gctgtgacaa
    19981 aagtcttgtc acagcc
//
LOCUS       DASHWW010000051        19606 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.051, whole genome shotgun sequence.
ACCESSION   DASHWW010000051 DASHWW010000000
VERSION     DASHWW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.051"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(77..149)
                     /locus_tag="U2R64_001989"
     tRNA            complement(77..149)
                     /locus_tag="U2R64_001989"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="U2R64_001990"
     CDS             530..1099
                     /locus_tag="U2R64_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEM8918790.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="U2R64_001991"
     CDS             1086..1946
                     /locus_tag="U2R64_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8918791.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="U2R64_001992"
     CDS             2136..2840
                     /locus_tag="U2R64_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8918792.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="U2R64_001993"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="U2R64_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HEM8918793.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="U2R64_001994"
     CDS             4677..5993
                     /locus_tag="U2R64_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918794.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="U2R64_001995"
     CDS             5994..6863
                     /locus_tag="U2R64_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HEM8918795.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="U2R64_001996"
     CDS             6918..7727
                     /locus_tag="U2R64_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8918796.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="U2R64_001997"
     CDS             complement(7830..8459)
                     /locus_tag="U2R64_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEM8918797.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="U2R64_001998"
     CDS             8629..9921
                     /locus_tag="U2R64_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8918798.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="U2R64_001999"
     CDS             complement(9997..10659)
                     /locus_tag="U2R64_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEM8918799.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="U2R64_002000"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="U2R64_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEM8918800.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="U2R64_002001"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="U2R64_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEM8918801.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(12934..14082)
                     /locus_tag="U2R64_002002"
     CDS             complement(12934..14082)
                     /locus_tag="U2R64_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8918802.1"
                     /translation="MLKVWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALENYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKMIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRKLSMDKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYEDGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLPNRAKELIES
                     VIADNILAGRPTDPDQYIFISTSGTPLTLHSFNAILHKVEEELELEKSLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKRAKQQVIDKLNSL"
     gene            complement(14184..14768)
                     /locus_tag="U2R64_002003"
     CDS             complement(14184..14768)
                     /locus_tag="U2R64_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HEM8918803.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(14895..15326)
                     /locus_tag="U2R64_002004"
     CDS             complement(14895..15326)
                     /locus_tag="U2R64_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEM8918804.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(15344..15664)
                     /locus_tag="U2R64_002005"
     CDS             complement(15344..15664)
                     /locus_tag="U2R64_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8918805.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            15958..16098
                     /locus_tag="U2R64_002006"
     CDS             15958..16098
                     /locus_tag="U2R64_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918806.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            16396..16653
                     /locus_tag="U2R64_002007"
     CDS             16396..16653
                     /locus_tag="U2R64_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HEM8918807.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(16624..16932)
                     /locus_tag="U2R64_002008"
     CDS             complement(16624..16932)
                     /locus_tag="U2R64_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918808.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            17010..17756
                     /locus_tag="U2R64_002009"
     CDS             17010..17756
                     /locus_tag="U2R64_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEM8918809.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            17771..17974
                     /locus_tag="U2R64_002010"
     CDS             17771..17974
                     /locus_tag="U2R64_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918810.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            18079..18378
                     /locus_tag="U2R64_002011"
     CDS             18079..18378
                     /locus_tag="U2R64_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918811.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDVLKEAS"
     gene            18378..18548
                     /locus_tag="U2R64_002012"
     CDS             18378..18548
                     /locus_tag="U2R64_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918812.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFIGLDE
                     AEYKTKKPVGRD"
     gene            complement(18607..19086)
                     /locus_tag="U2R64_002013"
     CDS             complement(18607..19086)
                     /locus_tag="U2R64_002013"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918813.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSNLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            19131..>19606
                     /locus_tag="U2R64_002014"
     CDS             19131..>19606
                     /locus_tag="U2R64_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEM8918814.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFSEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGG"
BASE COUNT         6539 a         3319 c         3962 g         5786 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtagtaatta agaaagaacc ctattttaac agggttcttt cttctttttt ttgttttatt
    12901 ttaagcaaaa ggggcaaaga aggggcaaaa atatcaaagg ctatttagtt tatcaattac
    12961 ttgttgtttg gctctttttg ttacatggtt ataaatagac agagttgtgt ttgcatcaga
    13021 atgccctaca cgctccataa tggctttaag aggtacgcct aattcagata atagtgaaac
    13081 gtggctatgt ctgaatatat gtgaggatag acttttttct aattccaact cttcctctac
    13141 tttatggagt atagcgttaa atgagtgcag cgtaagcgga gtgccacttg tagatataaa
    13201 tatatattga tcgggatctg tgggtctacc tgcaagaata ttgtcagcta tcacactttc
    13261 aatcaattct tttgcacgat tgggtaattg cacttcacgt tgcgaataag tattttttgg
    13321 agttgttttt atagcattat ccattttcac agatgtgtaa tctaaggtcc cattaatgga
    13381 aattttccca tcctcatagt ccttcatttg caaagctagc aattccccat atctcaaacc
    13441 agtcaaatat agaaattcag ctattatgcc gtgtagtttt ctgcgaggat tggaatataa
    13501 ctgtttcagt atttgatcaa tttcttcttt ctccagatat tttttatcca tagaaagctt
    13561 tcttttttct tcttccactt ttttaggatg gattttaact gctagagcag ggtttctttg
    13621 aatgtatttt ctatcaattg catagtttag cataacggat agagttgttt ttgtttgctt
    13681 tgtgtagttc agtgagagat caccaaaagt gtacatatct tcaatcatct tattaatgag
    13741 tgtctcatca atgtttctaa cgattgtatc atcgcttatg tgcttagaaa catgtttcat
    13801 catcattgga accttcaaat agctagtacg tttaacatgc tgcttataat attcatacca
    13861 ttctttatac agctcaccaa aagtgatatc tgatttattg taattttcga gtgcttcttt
    13921 aattttttta tctagaattt tctgagcttt tttccacgct tgtggtgaat tacttgtaag
    13981 tgttgtagat ttttttcgtg ttttttctgt ataaggatct acatatcttt caataaactt
    14041 gaattggcca tctttggttt gttcaaccca cacttttaac atctcctatc atttgctata
    14101 ataggcataa caaatagacc tatataggtt tgttttctaa aagcacgctc ttactctgga
    14161 cggtggggcg tgttttttat ttattataca gttgctttaa aaatagctgc tttttcaaat
    14221 gatactaaag gagagaagtg gatttctatt tctccctttt ggtttaacgt gaaatgagca
    14281 gttacatcca tttgttttcc tggagcaaca gatcccattg tattttcgtt ggcatatgtc
    14341 tctgattttt tgtcatctgg tccatatact tccacatctg tacctacagg gatatctgaa
    14401 tcgccatcat tttttacggt ataagtaatt tttactactt gtgcaggttg gttttcttca
    14461 aattgatttc tttcatcagt tagttctaca ctatttagtg tatattcagc atcaccaact
    14521 tttacagtgt caccaatctt atagaaggta tcgctttttt cttctttaga agatgaagca
    14581 gaggttgaag atttagttac tttttcgcca ccattatcac ttgctttatt actatctgat
    14641 ccaccattta aagcagaacc aataattata attaaaatta ctgctaatac ccaaaaccat
    14701 acttttttgt aaaaaggttt actaacttta tacatttttc cgtcttgacc cataactttt
    14761 tttgccattt aaatattcct cacttcttgt tataatatat ttgcgatctc agaaatgagg
    14821 tatgagtccg tgtgccagca cgggcttttt taatgttttg ctgaaatcgg tttttttaat
    14881 aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt aaaatagcat
    14941 tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata ctccataaat
    15001 ttttcgaggt taaactgaga ttcatcagtc agttcgttct caatatagat atttaataaa
    15061 attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt tgtagaagta
    15121 tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc atgagataaa
    15181 tgaaaggctt ctgcagtttc gccatataga ttttcattca aaaaaatgat tctaggcttc
    15241 ggataataga agccaggctc tttcatttcc atgtaaacta ctttcaaatt gtattcgctc
    15301 aacatttctt tcaatttcaa atacatacaa cccatcactc caactattca ttttcctcta
    15361 aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct tttccatcaa
    15421 aagaaaaaac agtatcgttt tctgataaat ccacatgttt aggggtttct ttttcttcgc
    15481 gccccagaag atagtctaca gagacatcga aatagtcagc aatttcttgc aaacgttctg
    15541 tagaggggtt tgagttctta agtctatata agacgttttt accatagcct aggtcttctt
    15601 caactttatt taatgatttt ccctgttttt tcgctaactc ttttattctc tcaaacgtta
    15661 tcatatcaat attcctttcg ttcaagaaaa aatatttaac tttatttgtt aaaattcgtt
    15721 gactatttta acaaaaggtg ttaatatcat tcttgtaaac aagtttaaca actaaaaaga
    15781 caacaaaaaa cactattgat taataaatgc caaccgccaa gaaagctttt aaaatcaatg
    15841 tttatatgtc ttatttaact atgttctgat tttaacactg tatgttaatt tagtcaacgc
    15901 agttttttaa aaagttgtta aatttgttta cgaatataaa agaaaggaga gaagaatatg
    15961 gaaaaaacag tctcggcaaa aatcgaagat ttgaaattag acatactgaa acaagcaaaa
    16021 gtggcgatgg aacacgcggt agataaagaa gactctgcca tggttgcagc catagcagag
    16081 attttagctc acgtttagtc atcgttttta cggtcttctg gaagctgacc atagataaca
    16141 gcataatgaa tatctaaata agcttgaaca atttcttttg gcgaaattga ttcgccttta
    16201 gtagatactt gtgattcgtg atttagccat gcaacaacta aatccgcagc gatttcaaac
    16261 ggcgttacac tttgtgtcag ttgccataaa gaatttcaca atatgtatgg tcgtggtaat
    16321 aataccaaag agcaatttga ggaatttatg gaaattaaaa aatacaaaaa atcatttatt
    16381 aaaggaggct aaacaatgaa caaggaaatg agccaaacaa tcaaggtaca aaaaatgata
    16441 gatgatctaa cacatggaat tgatagccaa gccgataaaa tcatcaagga attgcaagga
    16501 caaaaagtta aggatgcaaa aatgcttctc aagactatca actttgaaat gaatccaaca
    16561 aaaagaaagc tcgccgatgt gttggaagaa aagttggctt ccgctatcaa cgagcaagaa
    16621 ttactatttg aaaccgatac ttttaacagc tgatgtttta tagatgacag tttcatccga
    16681 atctatatca tcgccgagag aaaagaatgt tgcttttgac aaaaagccga taagacctac
    16741 aagcggtctt gatgttgcaa gagtagatac cccaatatca ccttgcaagg tattcacgta
    16801 aatttgagaa gaatagaaca ttccatcttt ttcttcgata tttgacgcat catcgtatcc
    16861 aacgaccaaa gtatcggcaa atattttgat tttttctcca tcaagcatag taattacaaa
    16921 ttctggtttc ataaattttc acctccttaa caattatttc agcctgtcac actgataagg
    16981 aaattatacc aaagaaagga atgagaaata tgaatacacc acaaattttt aatttcgagc
    17041 aaaacgaagt tcgaactatt ttagtaaatg atgaaccata ttttgtagga aaagatgtag
    17101 cagacgttct aggatattcg aatccgcaaa aagctattcg agatcatgtg gacttggagg
    17161 ataagacgca gaacgattcg ttcaccgtca atggaacagc agttgttttg attaacgagt
    17221 caggccttta cagtttaatc ttaaaatcaa aacttccctc tgccaaaaaa tttaaacgtt
    17281 gggtaacgag tgaagtcctt ccaacaatta gaaaaacagg tagctattca aacgtacctc
    17341 aaagttttgc acaagcattg cgtttagcag cggatttaga agaaaagaac caattactcg
    17401 aacaacaaat tgccgagtac gaaccaaaga ttagctactt agatacgatt ctttcatcga
    17461 cagatacggt agctacttct caaattgcag ctgattacgg aatgtcggca attgctctaa
    17521 acaaattgct aaacgagtta ggtgttcagc ataaagttag cggacaatgg atactttacc
    17581 gaaaacatat gaaccaagga tacacaaaat cgcacacaag tgagataccg aaagccgatg
    17641 gcggcactaa agttgtaatg aataccaaat ggacacagaa agggcgagtg tttatttaca
    17701 acttattaat cgcagagggc tattaccctc aaatggattt agaggaaatt ggttagaaag
    17761 gagttttagt atgactgaca ttgcagaaat cactcaacga gatagagaaa aaatcaaaga
    17821 atatgtcgaa agttcaaagt tcttaactta caccatgctt gctgaaagat ttggaattag
    17881 caaaagctac ttatctttaa ttttaaacgg taaaaagact tctgcagaag caaacagaat
    17941 tatagattcg attatcacta tgtacgaatt gtagagggag gtaaagtcgt tggaagataa
    18001 aatcattctt acaaaatcag agcttcaaga aatgttaaac atcgagtatg gaacgataat
    18061 ttttaggagg gataataagt gaaaaaacca acactttcag agctgataga agctgctgag
    18121 aaggcagtaa aaccagacga ctggtaccga caaagtttaa tcttggagaa gttccacggc
    18181 atgtcaaaaa ctactttagt tgaatactgc aaggaaatgg aaacaattcc tgaatttgca
    18241 gaaggaatac ttcgtccagg tcactcaacc acatttattc attaccatac ttttatttgg
    18301 tttttaaagt ggaaagacgc aaacaaatat cgtgtaaaaa gtttatcgcc ttcagatgtt
    18361 ttgaaggagg caagttaatg ggcaaattca acagagcact agtattcagc gcaccgctaa
    18421 tcatctacgc tttaggcctc tggggaagca gacaagcgtt gataggtacg attgtgtaca
    18481 tggtttggat ttttataggg ctggatgaag ctgagtacaa aacaaaaaag ccagtcggga
    18541 gggactgact aaaaaagtct aatgtctata agaaaggttt gacaataaat gaaagagtta
    18601 ttttttttaa taactttcat cattttttct atcagtgttt tctacattaa cctttgcgtt
    18661 gctagatttg ctttgaaaag ttttaggaac agcaaacgaa aatagagcta taaaagatac
    18721 gaatgtagta gctacgttaa attgctcttt agaaaacgtc aatgtcattg gaatgataat
    18781 tgatatcgat gagaaaatct ttgcgataat aactatccat ttttcaatta taaacatttt
    18841 taaattaagc accattagac aaaatgtagt tcctatatag aggataaatg aagatagaaa
    18901 taaacatatt agtccagttt taaaaaaaga gaagtaatct atgtgggcaa attctgttaa
    18961 tatgcttttt tgatttaaca caatcaaatt actgttggat aaaaatgaca gtaaggaaag
    19021 agttgctccg attactaaat aaaaaatagt tgttaacaat attatattat caatttttct
    19081 gctcatgttt tcaccccacc agaattatat caaaaaggag agaagaaata atgcaagaat
    19141 tagtaatttt gaaaaataaa gaagctgtga ctacgagttt gcaagttgca gaaagttttg
    19201 agaaaaagca tcaacatgtt ttaagagata ttgatgcact gaaaaaagat gtgtccaatt
    19261 ttggacagat gttttctgaa ggtaatgagc cagattccta cggaagaaat cgacgagttt
    19321 tcttcattag cagagatgga tttttcttgt tagctatggg atttacagga aagaaagcta
    19381 tttacttcaa acaaaaatac attgaagcat tcaacgaaat ggaagatgtt attcgcaaga
    19441 atactgttcc tcaaacaatt gaagatatga tgatctatca attagaagaa atgaaagatg
    19501 ttaaaaaaga tgtttccatg cttaaagata ctatgcgaat tagcggacaa caagagtttg
    19561 aaattaagca aaaaggaaat ataaaagtta tggaagttct aggggg
//
LOCUS       DASHWW010000052        19194 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.052, whole genome shotgun sequence.
ACCESSION   DASHWW010000052 DASHWW010000000
VERSION     DASHWW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.052"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="U2R64_002015"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="U2R64_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEM8918815.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="U2R64_002016"
     CDS             complement(1819..3042)
                     /locus_tag="U2R64_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HEM8918816.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="U2R64_002017"
     CDS             complement(3073..3912)
                     /locus_tag="U2R64_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEM8918817.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="U2R64_002018"
     CDS             complement(3929..4609)
                     /locus_tag="U2R64_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918818.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="U2R64_002019"
     CDS             complement(4611..5684)
                     /locus_tag="U2R64_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8918819.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="U2R64_002020"
     CDS             complement(6331..7002)
                     /locus_tag="U2R64_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8918820.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="U2R64_002021"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="U2R64_002021"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HEM8918821.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="U2R64_002022"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="U2R64_002022"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEM8918822.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="U2R64_002023"
     CDS             complement(10885..11751)
                     /locus_tag="U2R64_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8918823.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="U2R64_002024"
     CDS             complement(11911..14004)
                     /locus_tag="U2R64_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEM8918824.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(14753..15376)
                     /locus_tag="U2R64_002025"
     CDS             complement(14753..15376)
                     /locus_tag="U2R64_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918825.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(15535..16932)
                     /locus_tag="U2R64_002026"
     CDS             complement(15535..16932)
                     /locus_tag="U2R64_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8918826.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(16964..17935)
                     /locus_tag="U2R64_002027"
     CDS             complement(16964..17935)
                     /locus_tag="U2R64_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8918827.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            18309..18734
                     /locus_tag="U2R64_002028"
     CDS             18309..18734
                     /locus_tag="U2R64_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918828.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT         5550 a         4068 c         3232 g         6344 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    14461 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    14521 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    14581 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat acacggtgtt
    14641 caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttgcc
    14701 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt tttcattgtc
    14761 cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct tgattttctt
    14821 cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct gtcgactcgt
    14881 ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc cattccgcta
    14941 aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc acttttccat
    15001 ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc aaatgcttgt
    15061 ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata ttaataaatt
    15121 gattttcttc ttttcctttt ggcaaataaa tgtccaattc gcctttttcg taattggcag
    15181 ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta tctactgatt
    15241 ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc atttttcctg
    15301 aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag agaagaaacg
    15361 gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc tattatatac
    15421 aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg aacttctttt
    15481 tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc tttcttaagc
    15541 ctcaaatccg tttttatctg atacgtcttt gaaccaatga cccgattttt tgattgttct
    15601 ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat atgcattggt
    15661 ccacgaccag ttatccatac atgtccacat atgatagcct aaacaattgg caccttcttg
    15721 aatggcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat aatcatcgtg
    15781 gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac cgttttcaga
    15841 aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat catagattcc
    15901 ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca tttcataatt
    15961 gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt cttttgcttt
    16021 tacccggcgt ggctggtaat aattgatacc taaaagatct actgtatttt ctttgataac
    16081 cgtcaaatcc tctgcatgga tcacaggcat gagatcaagt tcttttacta tctcaatcaa
    16141 ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga agaacgcatc
    16201 tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat agcttggtgt
    16261 cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag atttgatggc
    16321 taacgctgaa gccaacgctt catgatagcc aacttggatc gcttttttca tatctgactc
    16381 ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg gttcattatg
    16441 agtaaaccat ttttttactt tcgaaccaaa caattcaaaa caacttttgg catatttttc
    16501 ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat acatcggcat
    16561 atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact catcaaaata
    16621 acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag gtatcaaacg
    16681 gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca actgtacatc
    16741 ctcttgatac ttcgtataaa cttgcgaggt tttttcaggt cctacttgat caaagaactt
    16801 ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat cgcctgaaat
    16861 ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg ctggaaattg
    16921 atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg attccatgta
    16981 tgatattttc catcacaatc actttttcat tttcttcctc ttcttttttg attcgtttta
    17041 acagctgttc tgctgctcgt tccccgattt tatctgttgg tggcgtgatc gtgattttcg
    17101 gaaggatact cagatcgttt ttatctaaat aatcatagtg actgaacgca atatccttcc
    17161 cgattctgac accttcttga ttgaaacatt cgatggcacc aatcgacata ttgtaattgc
    17221 tgacaaaaat agcagttgcc cctttttcta ataatgcttt tgccccgtaa tagccgcttt
    17281 ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt tggaccgctt
    17341 ctttggctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca gcaataaatc
    17401 cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca ctttctcgat
    17461 cattcactaa tattgtatca atacctgctg gtccttctgg acaattcaat gcgataactg
    17521 gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat aagaagacaa
    17581 tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt ttttctggct
    17641 gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact ctttcgatcc
    17701 ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt ccaatagaga
    17761 agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc aacgctgaaa
    17821 tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc aagtaacggg
    17881 aaactgttcc cactgaaaca ccagccatct tagccacatc acggatcgat gccatacatt
    17941 ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg atgaccgcat
    18001 tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca gtagagcaac
    18061 ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt ttaatatagc
    18121 atttttttaa aagattgcaa cactttttta aaacgctttc tgaaagtggc ggattttttg
    18181 cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg cgtttttctc
    18241 ttccatccgt ttgaagtttt acattccaat ggtataattt ctttatccta tcaaatgggg
    18301 gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga
    18361 ctggctgtga tttgtttggc ggctctgacc aatcctcgga cgaaacaacc gattcttctg
    18421 tcttaaaagc ggaaaaagca gataccacca acagtgtata tacgctaaaa gtacgtaaag
    18481 atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca
    18541 cgtatcagac acaaggaact gattcttctg aatcatctga agaaaaaaca gtgctgacag
    18601 atatcaagat cactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag
    18661 aaacaacagt catatttaca aaaatcggta attaccgttt gaaggatgag gatggcaaca
    18721 tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc ttttctgcta
    18781 tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag tcctgattat
    18841 tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg aagcttgagc
    18901 atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga atcttatcct
    18961 gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaac tcactatggc
    19021 tgatttttat gaacttcaaa ctcagcttct tcctttgatc aagcttcatc agtaaaacaa
    19081 acagtggatc atttcagttt acaaatcaaa gagtaaagat ttatttattt caaatatttg
    19141 aatataaaat aaccaaacga tagaaaggct tattctacat cacgtagtaa tttt
//
LOCUS       DASHWW010000053        19186 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.053, whole genome shotgun sequence.
ACCESSION   DASHWW010000053 DASHWW010000000
VERSION     DASHWW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.053"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(37..1188)
                     /locus_tag="U2R64_002029"
     CDS             complement(37..1188)
                     /locus_tag="U2R64_002029"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEM8918829.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1201..1638)
                     /locus_tag="U2R64_002030"
     CDS             complement(1201..1638)
                     /locus_tag="U2R64_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8918830.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1653..3419)
                     /locus_tag="U2R64_002031"
     CDS             complement(1653..3419)
                     /locus_tag="U2R64_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEM8918831.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3683..4360
                     /locus_tag="U2R64_002032"
     CDS             3683..4360
                     /locus_tag="U2R64_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918832.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4363..5490
                     /locus_tag="U2R64_002033"
     CDS             4363..5490
                     /locus_tag="U2R64_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8918833.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5690..6130)
                     /locus_tag="U2R64_002034"
     CDS             complement(5690..6130)
                     /locus_tag="U2R64_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8918834.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6141..8174)
                     /locus_tag="U2R64_002035"
     CDS             complement(6141..8174)
                     /locus_tag="U2R64_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8918835.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGLFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8176..9879)
                     /locus_tag="U2R64_002036"
     CDS             complement(8176..9879)
                     /locus_tag="U2R64_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8918836.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9973..10923)
                     /gene="manA"
                     /locus_tag="U2R64_002037"
     CDS             complement(9973..10923)
                     /gene="manA"
                     /locus_tag="U2R64_002037"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEM8918837.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10962..11987)
                     /locus_tag="U2R64_002038"
     CDS             complement(10962..11987)
                     /locus_tag="U2R64_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEM8918838.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12196..13065)
                     /locus_tag="U2R64_002039"
     CDS             complement(12196..13065)
                     /locus_tag="U2R64_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HEM8918839.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13524..15416)
                     /locus_tag="U2R64_002040"
     CDS             complement(13524..15416)
                     /locus_tag="U2R64_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918840.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15413..17140)
                     /locus_tag="U2R64_002041"
     CDS             complement(15413..17140)
                     /locus_tag="U2R64_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918841.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17156..17806)
                     /locus_tag="U2R64_002042"
     CDS             complement(17156..17806)
                     /locus_tag="U2R64_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEM8918842.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18010..18306
                     /locus_tag="U2R64_002043"
     CDS             18010..18306
                     /locus_tag="U2R64_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEM8918843.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18498..19118
                     /locus_tag="U2R64_002044"
     CDS             18498..19118
                     /locus_tag="U2R64_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HEM8918844.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
BASE COUNT         5455 a         3954 c         3381 g         6396 t
ORIGIN      
        1 aaaatttcgt cacattcccc tttttcgtat cctattttaa gcgacttgct tggcataacg
       61 gttcacgttt tgcttgatat tcccgattgt tttcggatca ttgattcctg tgacttcttg
      121 aatcaattgt tccaagtttt catggatctt catttcatgc aattgacggc tttgttcatc
      181 ttcaggatca tagtaattaa aaataatccc cattgttgcc gtcaaatgtg ggcaagtcaa
      241 gttatgttct tgtagttctc tcactggacg tgtaaatctt tcttgataac ctaacttacg
      301 taatggtgtc cgagcgacac gtgtgatcgc atcagagata tttttgtttt ggaagcgatg
      361 aatgattttt tcaatatacg catgatgctg ctctgcatca aacccccatt tggcaatcag
      421 caaacttcct gtttcctgca aaactgattt taattgtgcc acaactaacg catcttgcat
      481 tgcttcatca atggtctggt aacctaacaa ggcacctgta taagcgacag tcgcatgacc
      541 agtattgaca ctaaatagtt tgcgttcgat atatggttct agatcatcta catataaaac
      601 cccttttaat tggatttttt tattttttct ttggctatcg tcaatgaccc attctttgaa
      661 aggttccact tggacgaata aaggatcttc atggtgttgt aatgggacga ttcgatcgac
      721 tgctgcattt ggaaagccga tatatttgtc agtaaatgat gtttccggaa gatatttata
      781 cacttctttt tctagaaatg ctgaaccgcc aatcatattt tcacaggcaa tgatatctaa
      841 agatgttgtg cttccttcct tttctctttc ttggatacct tttgcaatca actcagcaat
      901 aaaaggtaag atattcgggc caatggcggt agtaactaaa tctgcttcag cgatttcttg
      961 gattactttt tctggatttg tttgattgtt gattcctttg acatttttta cagtgatttt
     1021 ttcttttgat tcatctgcta attcgatttc gtattctttt ctttcattta aagcatcaat
     1081 gatcgtgtga ttcacatcta cgaaagtaat ctcaaatcca ttagctgcca aaacctctcc
     1141 aataaatcct cgaccgatat ttcctgcacc aaaatgtact gctctcattt ttctctctcc
     1201 ttaagcaatt gctagatttt ccgttacttc ttctttgctg agcgcgtctg ctagctggac
     1261 aacattgtcc atatcactgc aataaagtgc gatttgctgt acaagttgca aatgctcatc
     1321 tccgactcct gcaataccga acaaaacagt cgcaatcttt tcttcttctt cggtaccaaa
     1381 atctacacca tctggtactt gaacgacaca gatgccggat tttttcacat atttttttgc
     1441 ttcatctgtt ccatgaggaa tcgcgataaa attccccata taaacagata acattttgtc
     1501 tctatctacc atggcatcga tatattcctc atcaacgcac cctgcttcta caagcatctg
     1561 accgcaatag cggatcgctt cttctttggt tttaaaagat cgattgagct cgatcatgtc
     1621 gaatggcaaa ctttgcatgc tgttttcctc ccttaagctg tctgtttcaa atattgtgca
     1681 atcgattcgt atttttgcgg attgaccatg ctgttgactg ataaatgaat ggattgaggt
     1741 gcagccatct gtactttttc cgctaaactt tctttggcta cgatcagtga atcaggttca
     1801 tcttttaaat cttggatatt gacttttctt aacgggatag ttaaatggtt cttgtctaat
     1861 atatctttga gcacggtcat ccccattgtt gctgatccgg aacgatcatc gtggacaagt
     1921 agaatctctt tgatttgttt gatgtttgct gaaagaaact cttctgctgg ctcattctca
     1981 atttcagaaa ctgatgtttt ctgcttgctg cttaattctt gaatgatttc atcatatcga
     2041 ggtgaattca aaaagttttc tactgagaca aaacgcgcgc tcggtgcttt ttgttttgct
     2101 ctttcttgta gttcgacctg agtaacgatc aatgtattcg agtcatctgt cagttggctg
     2161 attgcttgat tggtcaccgt ttgaggcaag tctgcttcct gtactttttt tctcaagatc
     2221 gaagcgccca tcgcacttga tcccattcct gcatcacaag caaaaatgat tttttgtacg
     2281 ccagagaatg tagctccttg aggaatacct tgggcacctt tggaagcttg cttagctgcc
     2341 tttgtctctt gaacagattt ttcgaagtct tcatttgtat ctttcgcatc cgctttcaaa
     2401 attactgcag aaataccaaa cgaaacagct gcggcaacaa tcacgcccaa aataacagga
     2461 aggtaagaat tgaacggtgt catcgctaga atcgcaatga tcgaccctgg agaagctggc
     2521 gctcttagtc cagcatccat caattggaaa atgaaacttc ctgacattcc tccgcctata
     2581 actgataaga ataataacgg tttcatcata acgtaaggaa aatagatttc atggatcccg
     2641 cctaaaaagt gaatgatcat ggctcctggt gctgaagatt ttgctgctcc tttgccaaac
     2701 aaagtaaaag caagtaatac gccaagtcct ggaccaggat ttgcttcaag caagaataga
     2761 atagattttc cagcctctgc tacttgttca gttcccaatg gtgtcaaaat cccatgattg
     2821 attgcattat tcaaaaataa gatttttgct ggttcaataa aaatacttgt caatggaatc
     2881 aaatgggcag ataaaatgat ctctacacct tttgccattg cttgagtcaa tgcatcgaca
     2941 actggaccaa tcgcagaaaa acctaataac gctaatccaa aaccgataag acctgctgaa
     3001 aaattattga ctagcatttc aaaaccggat ttgatccgtt tttggaatag ctgatcaaat
     3061 ttcttgatgg catatccacc aagaggtccc atgatcatcg cgcctagcat cattggaata
     3121 tctgttccga caatcacacc catcgttgca attgccccaa caactgatcc gcggtcacca
     3181 gcaattactt ttccgccagt ataaccgatc aataaaggaa tcagataagt tagcattggg
     3241 cttaccatgg tagccaaagc ctcatttggt aaataaccat ctgggataaa tagagccgtt
     3301 aatacacccc aggcaatcag tgctccaata tttggcatga ccatgcttga taaagtactg
     3361 cctaattttt gtaccctcgc ttttagcgaa atgttgtttt tgggaatcgt ccgttccatt
     3421 ttgtctctcc ctctctcctt ttgatactct aattgtatcc gcttactaaa aagagaaata
     3481 gtcgtacttt ggcacgaaac tttgtgccaa aggtttgagt atgtcagcaa aataaaaaga
     3541 tttcggtatc agaaaacttc aattttaaat aaaactgtta ttttaatttt tttataatat
     3601 gcaaacaata acttttgtta gcatttaatt tagatgtttt ccattctatt atgttattaa
     3661 attttatatt ggaggcctat ctatgacatt actgatcaaa aacatgaaca tgaaacgtgg
     3721 taaaaaacgt gtgattcgac aattgaatct tttagtagaa tcaggagaag tagctgcttt
     3781 gattgccccg aacggatttg gcaaaacaac tttgctgaat ggcattgccc aactgctgcc
     3841 aacaacttat gatcaattgt cccttcacaa catctctcct actgcttata cagattatcg
     3901 ccggtctttc ttttttctag aatcaacgaa tcagttatcc gactatctat cggctgttga
     3961 ttatttgact ttgatcaaat actattggca gagcaaagta gaatgccaaa ctgttttcca
     4021 acgattgaag atgactgagt accttacttt gccgattgga aaaatgtctc taggaatgaa
     4081 acaacatgtc ttgcttgctg cttacttgat cagtgattca tctgtcatgt tattcgatga
     4141 accgttgaac ggattagacc caggaagtat tgatatcttg aatagcctca tcagacaatg
     4201 gcagaaagag gggaagacga ttcttctttc ttcccacgct atcgcgaata tccaatcgat
     4261 ttgttctaaa gcatgttttc taaaaaatgg agaaatcgtc acagaatcct caaatatgga
     4321 agagatttta gctatttatc gtaaattata tgaggtgtaa ctatgtcttt acttacattt
     4381 gaacgcaatc tcttactaaa aaacaaagta aactttttat ttcctctatt gttggtcgtg
     4441 ctctttgcat tcccactttt ttttgatcat aaacttgctt atacagaatt cgatgaactg
     4501 aatcataact atgaagagat gcaacgtttg attgaaacgt tgaaagaaga tgagaatgag
     4561 aaagaatttg tggaaagttt agagaaaagc aacaaactga tcgaagcaat cttacatgca
     4621 aaaaacacag ggaatgtcca gcaaatggtc gaagcaactt atcattatga aaaagatata
     4681 ctggatcgac tgatttctgg tcaaagacaa ggaattccaa tcattgaaca acaaaaacgt
     4741 gtcgagttgc tccgttatat gaaagaacat cagatccaaa gatattctat ttttgacttg
     4801 ccagcgcatc tccctttagc aaattactac gaaaatattt tttcaggaat gatttctagt
     4861 tttttgattt tatgtataac cgccttgttt ctttcttcca tcatctctta tgaaaaaaga
     4921 aagcaggtaa tctctctagt caatctatta ccggatagta tggtaaagaa acatagcatc
     4981 cgttttacca tttattatgg tgcagctatg ctaagtctcg tgatgccatt tttgatcgtc
     5041 tctatactag taataatcaa aaatggtttg ggagacttcc gttatcctgt aggaacgatc
     5101 attggtcagg agatacgaat ccttccgatg tatgagtatc ttttccagag ctttctgttc
     5161 ctgttgttgt gggtgctctt tttaagtaca atcagttttc ttctatctgc tttatttgaa
     5221 cattctctag tcaatctttt aggtacactt ctttgtcttt tcttagcaga gtatcgcttg
     5281 ttttcttcga ttggatggat agaatcaatc agtcattact tgccaacttc ttatgttgat
     5341 tttcaaaatg tgatcatagg aggagatatt ttctcgccac tagcttcaga acaggttact
     5401 ttcatgaatg gtatcttgac acttggtata tggagtatcg ttttattatt cataggtatg
     5461 ggcactatct atataaaaaa gagctattaa aacacaaaaa taataggggc ggtgacaaaa
     5521 accttgtcac cgtcccctat ttcaaataaa cggttttcta gaataaatag ttttcaaaag
     5581 cttgcatccg cagtaataag aacctcccaa caaaaatagc tcctcttatt tttatcttgg
     5641 ttgaagttat tacttgatgc aaggcagctt tttttactgt gaacattggt tatatatgtc
     5701 catgttcaaa aatcatttgg acttcttcaa tggttttcgc atcactgagc gccattactt
     5761 ggtcgatgtc tgaacagaaa aaggctaaat cttggagcac cgctaactga tgttcttttt
     5821 ttaaagccac tacaaataag agtgtcgcga tttttggttc ctcttttgtt ccaaagtcca
     5881 caccatcagg cacttggact aaatagattc cttcttctac tacttcttca tctttgtcag
     5941 tcccatgtgg caaggctacg aaattcccga tatagacact cgctttttct tgtctttcga
     6001 tcattgattg gatatatgcc ggtttgattc ccccttgttg ggtcatccac tggccgatct
     6061 cggtcaacgc ttctttccaa ttttgatagg attgatcgag caatattttt tctgctggta
     6121 gctgtatcat cttttcacct tcatttcttt atttcttcaa tcaggatttt cgctaacaac
     6181 tgataaacga tttctttatt tcctgagcgg aagatctcgg tgttcaagtc attcatgatg
     6241 attgctccac tgatctttcc taaaagaatc ccgtcttttt cttggattgg cgaaggcgcc
     6301 agcataacta acatacggga caaatcgact ggctgtctat ccatcccttc aatggtcaac
     6361 ggatgtttca aattgaaaat acaaaagatc ggtttagaaa tcaatgagct ggatgtatgg
     6421 aataacccca tatttgtatg aggaataccg ataggtgctt gttcatatcg cttaagcagc
     6481 cggcgatgaa ccacctcttc atccgttact agtccttcag gaaaataagg aaataagctg
     6541 cgaatcgttt cggaaatcgt ctcaggatta tccagttctt ggataaaaaa aagaccgagt
     6601 aattgattga tttgatccat gaaatgcatt gtttcctcat aagtatcttc tatcatccac
     6661 tcgttattgc tgttatacgt aattttttgc ctttttttct tctcaatatg cgaaaaagct
     6721 tcttttagct gcttgacttc atcttctagc agtagcgggg agactaaaat atattttcca
     6781 ccgtatcctg gtaaaataga tgtagaaata acaacatcat attcttcttg taaatcgatt
     6841 ttttttaaat cagcaatccg atagaaatga atttgttgga tgaagggaaa ataccttttc
     6901 aatcgtagtt ccaacatgct agtagaagct aatccacttg gcgaaaatcc tgcaatactg
     6961 atattgcttt ctttcggact tcgttccaat gaattcgcaa aatgaaggac catataagcg
     7021 atctcttctt cggataattt tttttcttga aaaatccgct ctactgcttt acggattgca
     7081 ttcgcaactt cctcgtattg aaccatgatt ttttctaaaa tcggattggt cagtgtctct
     7141 tcttgtaaaa cggctcttga aaacacacca gataaatgag tcaacagcat tttgtacaaa
     7201 gtttcatctt cataaaaatg gacattcgtc tcttcactta cttcttgaat cagttgtttt
     7261 actaaataag caagctgtgt atcgaacgtc tcttcaaaga aattctgatc aaatgagttc
     7321 gtgaagtcat ttaataatcc tgcaaaaaag acgatctcat ttactggata aagttgtttt
     7381 gtctcagaag cgatccgtga aaacaatcgt ttagctgtct gtagtaattc tttgtttgcc
     7441 agactattat atgtctcatt tgtcagtaaa tgatttttag tcacacgctc catcgtcaat
     7501 gtcagcatca aaaccaaatg ttcaagcttt ctatcactta gattggtctt tttttggatc
     7561 aattcttccc cgattacttt gcgtgcaaga gatagatgtt gcggatcaac gaatcgaaaa
     7621 aaataattca gtgatgcatc gaaagaaata ctatgaaaaa gttcatattc attgatttct
     7681 aattctaata cattcgctgt cagaagccgg cggtattttt ccggtccttc gatctcgtat
     7741 ccctggttcc gaatgatttc caaaggcagt tggcgaatac tttcttccaa ctgtttgata
     7801 tctgcataaa aagtggtatt actgatgcga tatgattcca tgaaatgagc aagactcaac
     7861 ggctctgtcg tcagtaacaa ctcggctaaa atcgcgtgtt gtcgtttagc agtggataag
     7921 tcattacttt tcccatctgt attttctttt aattgctcta atacttcttc tgatgcctca
     7981 atgacaaatg agcctctagc tgcttttttc aaagaagcat ttaccgattt caatgagact
     8041 tcaagattat ctaattcgcg gtaaatagtc cgtttactga ccttcaataa attcatcatt
     8101 ttttggatag atacaggtga cgggctactg agaaattctg ctaataattg tttttctctg
     8161 ggcgataaat acatcttata tttctccctt cacgagtttt tcgtattcat tcgtagctac
     8221 ccaatgttca actagaacta gccgagggat cttttcttct agctgttcag ttacagctag
     8281 ttctctttgt gcgatataaa tcgtttcttc ttggattttg attttttcta ttgattcttt
     8341 tgagataaca aactgttttt tcgctttttt tgctaattga cttaaaatcg tcatgcccat
     8401 agtttgtgag ccgcgtctgt tgtttttata caaaaataca atattagcag gcgacttttt
     8461 ttgttctgtg atatctgcta tctctttttt ttcttcccgc tttggaaatt ggatcgcttc
     8521 ttttattcgt gacagcaaga tatctgtttc caaaaagtga tccagtacat agatttgact
     8581 ttgaggtact ttttctcttg caagacccgc tagttcatgt tgcacgataa ccagctgatt
     8641 tacttggtta ttcaattcat agatagagct gtatccgaca gaaagatcga ttttttctgc
     8701 tgctaatttc tttttcagca gggcggctcc catagcactt gatcccatac ctgagtcgca
     8761 agcaaaaatg acggaatgaa tgatagatgg ttccaagatt tctccccttt ctttgaccgt
     8821 tttgttctct ttttctttat ttggtaattt caatagtatc gctgcacaaa tgaaggtcac
     8881 aaatgtactg attgctatcc ctatacttac cccagctagt tgtggataag gcgcattggc
     8941 aaaaatcacg agtagtgacc caggcgatac aggtgcagct aatcccgtat ctaaccattg
     9001 aaatatcaac gtgccgcttg ccccaccagc cattacagct aaaaatagat acggtcgcag
     9061 caagacaaat ggaaaataga tttcgtgaat cccgccaatc gcatggatca tcaatgctcc
     9121 actcgcattt actttttcct gtttttctgc aaaacaaagg atagaaagta agatccctaa
     9181 accaggtcca ggatttgcct ccatcaaaaa taaggaagag tacccgactg tttgtgagaa
     9241 ttcgattcct aaaggtgtca atacaccatg attgattgca ttattgaaaa atagtacttt
     9301 tagaggttct aagatcagac tgacaagtgg taacagattc attgtgacta gccaagacac
     9361 aacggaggcg agcaacaagt gaacactatt taaaactggt tcaataaaaa cgattccaat
     9421 tatacaaata acgctaccag tcagtcctac tagtaggttg ctgacaagca tttcatatcc
     9481 agccttgaat ttcacgtgga atctagaaac aaattgttca tatacgatgc cggcaagcgg
     9541 cccgataatc atcgctccta cgatttgtgg agcattggaa cgagcgatca accctaaaga
     9601 agcaattgca ccggcgactg cccctttttg tccccctacc gatttcccgc ctgaataact
     9661 gatcaagatg ggtaaaagca gctggatcat ccaatggcat acctcttcta atgtggtgtg
     9721 caaatcgcca gacacacctt ttgttgctaa tgacaagatt ccccaagcga taaacagact
     9781 tagatttggc atgatcattt catttaagtg atgtccagct tttctcagtt gtttcataga
     9841 cacgcgactg ctgttgtttg ctttccattt gtattccatc tttttcacca tacttctatt
     9901 tattgatgga cggattttat gtagaaaaag cagcaaacga aaaaccgtct gctgctttca
     9961 gctatctggg aactatttgc ctggttcagt cgcaatgatt gctagttcac cttggaccgc
    10021 ccactcagaa acgccatttg gaataataca gcttgttcct ttttctaatg gatatgtttt
    10081 tccgtcaacg acaaggtctc ctgctccttc gattaccgtc atcaatgtat aaggggcttg
    10141 ttttttgaaa gatgtgattc ctttaatatc ccactcatat acattgaaaa actcagtttc
    10201 taaataagtg acgatcgatg aattcccttt tcggacttct ttgatttgta attctggtgt
    10261 tttcgcaggg acagttgtta catcgatcga ttgttggata tgcagctctc ttgtttgtcc
    10321 ttgcgcatct tttctgtcgt agtcatacac gcggtaagtc gtgtcagaac tttgctgtgt
    10381 ttctaaaatc atgattcctt taccaatagc atggatcgtt ccgcttggta cataaaagaa
    10441 atcacctttt ttaactggta ctttcttcaa aaggtcatcc cagcgcccat ctttgatcat
    10501 ctcagctagt tcttctcttg tctttgcatg atgaccatag atgatttctg caccaggttc
    10561 agcatcgatg atataccagc attcagtttt tcctaattca ccttcatgtt tcatcccata
    10621 ggcatcatct ggatgtactt gtacagatag atcatcttct gcgtctaaga tcttgatcaa
    10681 taatggaaac actggttctg aaggatggcc aaacaattcc ttgtgttctg accatagttc
    10741 atctaatctt ttccctttga attcgccatt ttctactaca ctgacaccat gaggatgcgc
    10801 actgatcgcc caatcttctc cgattttatc gttagggata tcaaaaccaa agactgaacg
    10861 taaacgactt cctccccaaa ttttttcttg aaaaactggt tttaaaaaca taggttcctg
    10921 cataattcaa actcctctca tttttcatag ctattatagc attatttcgg taataccgct
    10981 ttctctttca aaaagttttc aacaatttca tctcgacata tgagatactc cgcacgatga
    11041 tcgacaggat gtacgcgatt tgacaaaaat atcaacgctt cttgtgtttt tatatcaatc
    11101 aagaaaaacg tacctgtata accagtatga aaaagaatcg catgaccgtc ttctacatcc
    11161 ttttttaagt cccatcctaa agaacgatag ccattttttt tcggtgtttg atcttgcagt
    11221 aaagaatcaa tcgtctcttc ttctaaaaaa cgaccattac ggatttttcc cttgttcaaa
    11281 tacatttgga caaaagtaat gctgtctttc aaatcaataa agagacccgc gttacctgca
    11341 tgttcagcca aaactcttgc tttcggatca tgagtttgtc cacgcaaaac ctcacccgaa
    11401 ggcagttgtt ctgtgggaac gatttttttg gaaggaaaag gaagaaataa gctgttcatc
    11461 attcctaatg gttccaatac ttgttcttga aagatttcca ctgcagtttc ttggtaaatt
    11521 tcctctagca tcaacccaag aagaatcgta ccggcatctg tatattttac ttcttttcct
    11581 agttgctcac ctggttctag cttcaaataa gcggcgatca attcttcctg agatagctta
    11641 tctctgtttg gtatccatgt tttgatatca gaagtatgtg tcagtaaatg acgcaaagtg
    11701 attgtctgat tttcaaattc aggaagatat ttatgaagcg gttgatcgag ttctatcttt
    11761 ccatcttcta atagacgtaa aactaatgaa gtggttgcaa cgactttcgt cagtgaggct
    11821 gcatcaaaca acagatcttc tgtcatcagc tgcttttcag gaacgacttg ggcaaagccg
    11881 gctgtaaatg tttctacttg attttctttt atgaaggcga ctgctacacc tggataaaat
    11941 ccttcttcca tctttttcaa aataagctgt ttcgtgtgtg gatacatctt tttctcctgc
    12001 ttttctatca gattcttaca gtccaagctt aaagcttaat ctatgaggaa tcaacctttt
    12061 ttacacaaaa aaactgcgcg aaaaaccgcg cagtttcccc cggtatacta ttttctcttt
    12121 ctatctctag aataagcgat agtatgaccg ttcataaaat gacgagacat gcgacaatcg
    12181 ttaagaaaga aaaagttaag cgtcgcatcg aatgtcagtt ttattctttt cttttggctc
    12241 actgacgaac caccattcga ttcctatagc atcatagatt gtgagtactg tgtgcttttt
    12301 gtctaagaag aaatcaactg atagttgctg caagtgagca atcagtcctt ccatgctttc
    12361 agtatcgatc atgaatttca gaaaatcaag tccaatcact tcatctgtag gcaaatcaat
    12421 tgcgcctccg ctagcttctg tcaaaccaac atggaaatct ccttcattca atacatggat
    12481 gccctcttct tcattatgta ccttcaaacc aagtacatga ttaagaaatt ggcgttcttt
    12541 tgttaagtta gtaacattta aatggatttt ttcaaaataa gaacctgttg atagtttact
    12601 gaatttttct tcagattttc ttaataatgc ttcttgatcc attgtttctg gaatttctct
    12661 ttggtcgttc ttattctctt catggtaaat ttccaattca ttctcttctg ggtctacgag
    12721 caaaatcccc atacgtccat gatcttctaa agcttctttg attggataat tcattttacg
    12781 gatacgacaa aggatatctg ccatttcttc tgtgctaggg ataatcaatg aaaaacggtt
    12841 cagctttttg atcaccccca tgtgatcatt cgctctagga ctttcttcca gcagcaacat
    12901 ttcacttcca gcttcttctg ttcctaaaat ggctaattcg ttttcttctc ttttcaaatc
    12961 aaagccaaca acgttcttgt aaaaatcaat cattttatct cggtctttca cccgaatggc
    13021 tacacttttt aaataggtgg cagcccccaa ttgaaaatct ttcatatttc ttgctcccct
    13081 ctacgtcaag ctttatttta acgatggatt cttcttcttt caagcaataa ctttgatttt
    13141 gttaaaaata atgtgagaaa attcgcattt tgcttgtttt ttgtaaatta atgagtaaaa
    13201 actcttataa aaagaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    13261 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt
    13321 gaacaccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat tagagataca
    13381 aaacggaaaa atagcttctc atattttgcc gttttttgag ctaataccga aggacagctg
    13441 attgaacacc gtttattcgg aaaaagggac tgtgacacga cttttgtcac agcccctaaa
    13501 aaaaataata aatttgtact attctatgaa gcttcttctt cagaaaactg actgttataa
    13561 agatctgcat agaatccgtc tttttccatc aatgtatcgt ggtttcctgt ttctacgatc
    13621 gaaccatgat tcatcacaat aatgttgtct gcatcgcgta ttgtagacaa gcggtgagca
    13681 acaacgaaac ttgtccggtt ttccaatagg cggttcatcg ctttttgaat cagtatttct
    13741 gttcgtgtat ctacactaga tgttgcttca tcaaggatca ggacatctgg atttgctaag
    13801 aatgcccgcg caattgtgat tagctgacgc tgcccttgcg aaatattgct tgcatcctcg
    13861 tttaatacag tgttatatcc ttctggcaat ttacgaacaa aatcgtctac gtgagcagct
    13921 ttagcagcct caatgatttg ttcgtctgtt gcatcgtcgt tcccatattt gatattgtca
    13981 tagatacttc ctgtaaacag ccaagtatct tgcagtacca ttgaaaactg tgcgcgcaat
    14041 tcatcacgtg aaagatcacg ggtatctaca ccatcgtaac gaatactacc tccagaaaca
    14101 tcgtagaacc gttcaagaag gttgatcagt gtcgtcttcc ctgcaccagt cggacctaca
    14161 atagcgacca tctcaccagg tttgacatcc aagttaaaat cagtcattag caagttatct
    14221 ggtgtgtagc cgaattgaac attttcaaaa cgaactttgt atggtgtatc tttttcttct
    14281 ggaaggccag atttttcatt ggacatctct tcttcatcca acacttcaaa tacccgttcg
    14341 gctgaagcaa ctgttgattg gatagtgttc atcaaacttg caagttgagt gattggttga
    14401 gagaactgtg ttgtatattg caagaacgct tgaacatccc ctaatgtcat gttcccattt
    14461 gcaactttta ctccgcctag tacagcgacg aacacatagc ctagattttt aacgaaattc
    14521 atcaacggca tgatgattgc cgaaataaat tgagctttcc aaccagcggc atacagattc
    14581 tgattttctt tttcaaatac ttcctggtct ttttcagtat gattgaatgt tttaacaatg
    14641 gtatgaccac catatgtttc ttctacttgg ttattcaata aacctaaact tttttgctga
    14701 tctgcgaaaa acacttgtga tttcggcgct acgatcatca cgatgatcaa gcttaaaggg
    14761 atcatcaata acgcgactaa cgtcaattgc cagctgattg aaagcatcat cacgatgacc
    14821 ccaatcaatg tgactgcact agttacaaat tgagtcaaat tttgctgcag cgtgcttgcg
    14881 atgttatcca tatcattgat tgctcgagac atgatatccc catttgtatg tgtatcataa
    14941 taggaaatcg gtacacgatt cattttggct tccaaatcat gacgtaattc ataaactgtt
    15001 cgttgggaaa cacgtgtcat aataaattgc tgtaaaaagt tgaatacagc agaaatcaaa
    15061 tacatcacga ttactgtcgc aatgatctgc gcgattttat caaagtctat cggaaatttt
    15121 gttacttgtt ggccttgttg catctgttga gcgccagcca ttacaccttt gaatatttct
    15181 gtggttgctt tccccaagac ctttggtgtt tggatttgga agatcacggc tgctattgct
    15241 agtacaaata cagcgatgat cgcaaccata cgtttagaca tatagccaaa caatcggcgt
    15301 accgttcccc agaaattttt aggcttttca ccttttacac cgagatttct gccaggtcca
    15361 ccatgtcctg gaccgcctgc tggtccatga gagggacgtg tgtttgtttt actcatgcta
    15421 agtcctcctc tcttagttgt gaatgaacga tttcttgata agtttcgttt gttgctaata
    15481 gttcttcatg tgttcctttg ccaaccagtt ttccttcatc tagcacaagg atcatatctg
    15541 catccattac tgtacttact cgttgagcaa ctaaaacggt gatactttct ttcatattcg
    15601 ttttcaatgc ttggcgaaga ttggcatccg ttttgaaatc caacgctgag aaggaatcat
    15661 caaacacata gatatctgct gttttgacta atgcccgtgc aattgccaga cgctgtcttt
    15721 gtccaccaga gaagtttcct cctccttgtt ccacatggct atctaagcca tcttccatct
    15781 ctgaaacaaa atctttagct tgtgcgattt ctaatgcttt ccaaatcatt tcatctgttg
    15841 catccggctt accatactgc atattgtctc ggatcgttcc agagaacaga actgcttttt
    15901 gaggaacaaa gcccattaat tctcgcaaat tatattgagt catgtcacta atgtccgttc
    15961 catttatttg gatcgaacca gattcgatgt catataatcg agggatcaaa ttgactaagg
    16021 tcgttttacc tgaaccagtc ccccctatga ttgcgacgat ctcgcccgac ttggcttgga
    16081 aatcaatatc ttccaatgca agtttttctg ctccatgata tcgataattg acatgattga
    16141 aggccaatgt tgcgtttttt ccagcaaaag aaactgtttt aggattttca gggtcatgga
    16201 taccgatttt ttcatccaac acttcattaa tacggtcagc tgaagcttgt gcacgaggca
    16261 ccatgataaa aatagcggaa agcatcataa agctgatcaa gatctgcatc gcataagtca
    16321 taaatgcaat cagattaccg acttccaaag tcatatctgc tatgtagtgt ccaccaaacc
    16381 aagtgattgc tacgtttgta ccgctcatga tcaatgtcat cattggcatc atcaatgcga
    16441 cgatcgtatt aactttgatt gccgtatttg tataatcttt attcgctaaa tcaaaacgat
    16501 tttcttcaaa gcgtgtctta tcgaatgctc gaatcactct gacccctgtc aatccttctc
    16561 gaaataccag gtttaaacgg tcagttttct tttgcatact tttgaataat ggaacagcaa
    16621 agtacatgat tccgccgatc aaaataatca ttactgggat gacaactaag aagatttttg
    16681 tcaactgatg atctttttga taagcaagta tgctcgcgcc aatcaacgtg attggtgcat
    16741 tgatcatcat acgtaaaaac atttgtgtaa ccatttggat ttgagtcaca tcattggtcg
    16801 ttcttgtgat caaagaggcc gttccatatt tatcaaacgc atcttttgtc agactctctg
    16861 attttttata gacatccgta cgcaattgct tacccagttt ctgtgattca cgagtagcaa
    16921 aaaatgtatt tgcgatagca gctaagatac tgatcaaaga aaagccgatc atcacaaaac
    16981 ctgtatgcca aatataatcg acatctcctt gcgctacccc tttatcaata atattggagg
    17041 taagtgtcgg caaatataaa tctgccagta cttggatcac catgaaaact gcagctgcaa
    17101 ttgctgaagt caaggagatc cgttttacga tttttagcat ctagttccct tctttctatt
    17161 tatatactcc gtttttcagc caagaaagtt tcaaattgaa ttcactgatt gcttgctcta
    17221 ctgagtaatc ttcagatgtt gaaaataagc gatacgaatg cgcaattgtt gtaaatacag
    17281 tattcatcac taattggatc agtaattcca attcatgatc attttttact ttcagcttcg
    17341 tccgatcgat caattcaagc aactcttttg catcttgttt gtgttcttta tgtggatcgt
    17401 gaggcgtttt ttggcgactc gtatgaggag cgacttttct tgaggcacgg taatccatgt
    17461 tcataaacaa gttacgataa aaagaagcat tctcgccttc caaaatctca taaatcattt
    17521 tagaaaaata ggattcgaat cctttgaata gatcaccatc ggattctttc attagttgta
    17581 acatatcttt agagctgtca cgtctcattg tctcaaagta ataaaaataa agatcctctt
    17641 tatcttcaaa atactgatag aaactgcctc tagggatatc cgctaatttg acgatattag
    17701 caatcgaagc ttcttttaag ggtactctag aaaactcgat tctcgcagcc tcgattagtc
    17761 ttttttgttt ttctttaggc aaatggaaaa atgtctgtgt cggcatatgg attctccttt
    17821 ctttcaagat gacacattgt catatgacgc tatgtcatta taacacctcc tacctgtttt
    17881 gcaagacatt tgcatagttt ttttcattat catccgatac attaaaaaag tgataagagg
    17941 aatccttcca tttgaattaa tgagagttgc ccattaaaat agccacatac taaacaaagg
    18001 atgagataaa tggcccaatc aattagtgtc caagacttca ataaattgcc tctcgatgct
    18061 gacagcatcg ttttagatac aagaaatacc ttagattaca caaaaaacca cttaagccac
    18121 tcgctttcta tccccgctgc tatcttgcca agacaattaa aaaatctaga tccaaagaaa
    18181 ctttattata ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact
    18241 gctaatggtt ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt
    18301 gcttgaatat tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc
    18361 ttttataccc tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag
    18421 ccttttcttt ttcgagtaaa ctgattttgt tagtcatagt tataacaatc atagcaataa
    18481 aaggagaagg taagcatatg gcatctgttt tagtagtcaa aggtcatccc ctaactgcag
    18541 aagaatcgcg cacagttaag gcattgacgt cttttttaac aagttataaa gaaaatcatc
    18601 cagatgatga agtgactgtt ttggaacttt atcgcgatga tattccggaa atcgatgaag
    18661 aattattatc aggttgggaa gcattacgtg ctggtgcaga attcacttcc ttatcagaaa
    18721 gtcaacaaca aaaaattgct cgtttcaatg aattgactga tcagttcctt gctgctgata
    18781 aaatcgttat cgcaaacgcc ttatggaatc taaatatccc aacaaaatta aaagcttggt
    18841 tcgataccgt caatgtagct ggaaaaacgt tccgctatac agaaaacggg ccagaaggat
    18901 tagtgacagg taaaaaagca ctgcacatcc aatctaatgg cggtgtatac aacggacaag
    18961 actttgcctc tcaatatgta aaaggtattt taaactttgt aggcatcgat caagtagatc
    19021 agctattcat cgaaggaatc gattatgacc ctgaccgtgc agatgagttg atgcaaaatg
    19081 cattagataa agctgctgct ttaggtaaat cattttaaaa attgagataa atgcatacaa
    19141 aagagacaga ggaaaaaatc ttcaaagcag catttgtgcc ttggat
//
LOCUS       DASHWW010000054        18956 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.054, whole genome shotgun sequence.
ACCESSION   DASHWW010000054 DASHWW010000000
VERSION     DASHWW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.054"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(21..251)
                     /locus_tag="U2R64_002045"
     CDS             complement(21..251)
                     /locus_tag="U2R64_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918845.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="U2R64_002046"
     CDS             complement(687..1253)
                     /locus_tag="U2R64_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8918846.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="U2R64_002047"
     CDS             complement(1253..2209)
                     /locus_tag="U2R64_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEM8918847.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="U2R64_002048"
     CDS             complement(2209..2865)
                     /locus_tag="U2R64_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEM8918848.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="U2R64_002049"
     CDS             3235..5253
                     /locus_tag="U2R64_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8918849.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="U2R64_002050"
     CDS             5680..8094
                     /locus_tag="U2R64_002050"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEM8918850.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="U2R64_002051"
     CDS             8442..9995
                     /locus_tag="U2R64_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEM8918851.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="U2R64_002052"
     CDS             complement(10376..12160)
                     /locus_tag="U2R64_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918852.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="U2R64_002053"
     CDS             complement(12175..13896)
                     /locus_tag="U2R64_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8918853.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="U2R64_002054"
     CDS             13996..14757
                     /locus_tag="U2R64_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8918854.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="U2R64_002055"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="U2R64_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18956
                     /locus_tag="U2R64_002056"
     CDS             16664..>18956
                     /locus_tag="U2R64_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918855.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQ"
BASE COUNT         6227 a         3363 c         3802 g         5564 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatttgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtttaac
    18901 tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat atcagc
//
LOCUS       DASHWW010000055        18272 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.055, whole genome shotgun sequence.
ACCESSION   DASHWW010000055 DASHWW010000000
VERSION     DASHWW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.055"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..174
                     /locus_tag="U2R64_002057"
     CDS             <1..174
                     /locus_tag="U2R64_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918856.1"
                     /translation="SGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            167..307
                     /locus_tag="U2R64_002058"
     CDS             167..307
                     /locus_tag="U2R64_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEM8918857.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            377..796
                     /locus_tag="U2R64_002059"
     CDS             377..796
                     /locus_tag="U2R64_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEM8918858.1"
                     /translation="MEKYLNTLSVMTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTG
                     LAKAWKLKEISSEIGFEGLLKKVLIFVVIAVAVDVQKIVGNSIPLREIVIMFYVANEG
                     ISFLENISVFLPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            793..1803
                     /locus_tag="U2R64_002060"
     CDS             793..1803
                     /locus_tag="U2R64_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8918859.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYSINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLWVT
                     QNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTL
                     SDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPD
                     VNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIP
                     KR"
     gene            1918..3126
                     /locus_tag="U2R64_002061"
     CDS             1918..3126
                     /locus_tag="U2R64_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918860.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFRKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
     gene            3110..3280
                     /locus_tag="U2R64_002062"
     CDS             3110..3280
                     /locus_tag="U2R64_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918861.1"
                     /translation="MITIIKPQEKSPVLKFNESNLAHNKMSITDTVFDVMVEQQKKIN
                     NNNRQRKEINQY"
     gene            3535..3608
                     /locus_tag="U2R64_002063"
     tRNA            3535..3608
                     /locus_tag="U2R64_002063"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3569..3571,aa:Ile,seq:cat)
     gene            complement(4121..4423)
                     /locus_tag="U2R64_002064"
     CDS             complement(4121..4423)
                     /locus_tag="U2R64_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918862.1"
                     /translation="MLIEGKTQLWFKFDPSNRFIKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            4402..4809
                     /locus_tag="U2R64_002065"
     CDS             4402..4809
                     /locus_tag="U2R64_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918863.1"
                     /translation="MSFLLLKYLEIYSVKKNKLIGENDSPIKTPIELSLRNRMGILQR
                     SEIVKELFYHKFSYEIRLDDTYEHYRIVFFVYNSIEDATATTALTFGFTKNGTINSDK
                     TRQAATESDDICKKVCNGEENYWIGEEKLNEIY"
     gene            4796..5248
                     /locus_tag="U2R64_002066"
     CDS             4796..5248
                     /locus_tag="U2R64_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918864.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            5241..5639
                     /locus_tag="U2R64_002067"
     CDS             5241..5639
                     /locus_tag="U2R64_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918865.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
     gene            5951..6024
                     /locus_tag="U2R64_002068"
     tRNA            5951..6024
                     /locus_tag="U2R64_002068"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5985..5987,aa:Ile,seq:cat)
     gene            6404..6565
                     /locus_tag="U2R64_002069"
                     /pseudo
     CDS             6404..6565
                     /locus_tag="U2R64_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            6715..6915
                     /locus_tag="U2R64_002070"
     CDS             6715..6915
                     /locus_tag="U2R64_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8918866.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7169..8848)
                     /locus_tag="U2R64_002071"
     CDS             complement(7169..8848)
                     /locus_tag="U2R64_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEM8918867.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(8850..9062)
                     /locus_tag="U2R64_002072"
     CDS             complement(8850..9062)
                     /locus_tag="U2R64_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEM8918868.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9455..11185
                     /gene="efrA"
                     /locus_tag="U2R64_002073"
     CDS             9455..11185
                     /gene="efrA"
                     /locus_tag="U2R64_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HEM8918869.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11182..12942
                     /gene="efrB"
                     /locus_tag="U2R64_002074"
     CDS             11182..12942
                     /gene="efrB"
                     /locus_tag="U2R64_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HEM8918870.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13037..13234
                     /locus_tag="U2R64_002075"
     CDS             13037..13234
                     /locus_tag="U2R64_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918871.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13387..13872
                     /locus_tag="U2R64_002076"
     CDS             13387..13872
                     /locus_tag="U2R64_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HEM8918872.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(13976..14569)
                     /gene="clpP"
                     /locus_tag="U2R64_002077"
     CDS             complement(13976..14569)
                     /gene="clpP"
                     /locus_tag="U2R64_002077"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HEM8918873.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14749..15276
                     /locus_tag="U2R64_002078"
     CDS             14749..15276
                     /locus_tag="U2R64_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918874.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15367..16104
                     /locus_tag="U2R64_002079"
     CDS             15367..16104
                     /locus_tag="U2R64_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEM8918875.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16108..17025
                     /gene="miaA"
                     /locus_tag="U2R64_002080"
     CDS             16108..17025
                     /gene="miaA"
                     /locus_tag="U2R64_002080"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEM8918876.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17027..18256
                     /gene="hflX"
                     /locus_tag="U2R64_002081"
     CDS             17027..18256
                     /gene="hflX"
                     /locus_tag="U2R64_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEM8918877.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         6103 a         2985 c         3731 g         5453 t
ORIGIN      
        1 agtggcacag cggttgacga tattgaagat gtcgatcagt tgaagcaatt aaatgctcta
       61 ctgacaaaac aattggcgat atcggtacag gaacaagaaa aaatgcaaca aatgttagct
      121 caattgacga tggaagtcgc aagtattaag aatggaggga aaagtaatga atagttttcc
      181 gggctttgaa aatataaaac aattttatga ttggggatgt tatacggacc aagatttact
      241 tgactatgta aacatgaact gtttaacaaa agaccaatat aagcagatta ctggaaatga
      301 aatttaatta agcacaaagt taaataaaaa gcgtactcaa acgagtgcgc ttctttgcat
      361 aaaggagaaa tagatattgg aaaaatattt aaatacactc tcagtaatga caggggtgat
      421 aggcgggaca attgttggtt tattgggagg gatggacaat atactacatg ttttaatttt
      481 tcttgtgggt gtggacttct taactggact tgctaaggca tggaaattga aagaaataag
      541 tagtgagata ggtttcgaag gattgttgaa gaaagtctta atcttcgttg tgattgccgt
      601 tgcggttgac gtacagaaaa tcgttgggaa ttctatacct ctaagagaaa tagttattat
      661 gttctatgtt gcaaatgaag ggattagttt tttagaaaac atttcggtat tccttccttt
      721 gccagataag ttaaaagagg tattccaaca aatacgaaat gatactgaaa ataaagaccg
      781 aggaggaacc aaatgaaaaa gaaaatcttt gtaggagcta ttatagctct ttttttattg
      841 ccaataaacg cctttgctta ctcgatcaac aatgaattca atttgggcgc aaacgaaggt
      901 agttctcaag tagcaaataa ccaatacatc ctattgcatg aaacagcaaa cgaaactgcg
      961 acaggacgaa atgaagcgca gtacatgaaa cgttcttggt acaatgccta tacagcgtat
     1021 attgttggcg atggtgggat cgtttaccaa gttggacaac ctggttatgt acaatatggc
     1081 gctggttcat atgctaatgc aaatagtcct gtgcaaatcg aactgcaaca tacgcacgat
     1141 aaagtaacgt ttgaaaagaa ctacaaggca tatgttgaat tagcgagaga ttccgctaat
     1201 aaatacggta ttccacttac attagacaca ccgtataatc aaccaggaat caaatcacat
     1261 ttatgggtaa ctcaaaacat ttggggcgat cacactgatc cgtatggata cttatcagaa
     1321 atgggtgtaa gtaaggaaaa actggcttac gatttagctc atggatttac agacgaaaac
     1381 ccaacgactt ctgagaacaa gcctgtcatt gatccaaccc gagcaggtgc agcaaatcca
     1441 actttatcag atggaacgaa ccattctcac attgatcagt ttggagaaat cgaaaatgcg
     1501 aacttacacg tcgctggatg gcacatcgct aactataaat acgagtatat tttcattatg
     1561 gactacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagaccggat
     1621 gtaaatcaag cttataatac ttctggaaac gttggctatc atgtatcttt taacatgcgc
     1681 aatttcccta ataagaaagt atacgtcatg atgcgggcaa cgaatgatcc agaaggaaac
     1741 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
     1801 taaaaatagc tcctcgttga ggagcagtac atagaattga aaattaacgt taaatcaaaa
     1861 aaatatttac aagatgttta tttaagtaga taataaaaga aaaaagcagg tgaaattgtg
     1921 acagcagaaa ttggtattat gaataaaagt ggaatcgtgt tagcttcaga ttcagcatct
     1981 acgattggag atagcaaagt atataatact gcaaaaaaat tatttacttt ggattccatg
     2041 cattctgtag gtatcatgat atatggtaat gctgaattta atggtattcc ttgggaaata
     2101 atcattactc aatataagaa aagcattggt agttctgttt ttaatacttt ggaagaatac
     2161 gcggataatt ttatagaatt tgtcaaaaca gcatctttta ttagaagtga acagaccgag
     2221 caagaacaaa tgattggggt ttttcgaaaa ataatttcag gtttatttga gagtatagaa
     2281 gtagatatta actttttaat aagccaaggt acacaaatag acaaagatgt cctagtgaag
     2341 ttattacaaa caaaaatgaa taccaatttg tctcaacagt cccagacatt cattttagat
     2401 attgaaaagg cgttatttct tagtaactat ggagaaatat taaaagatat tcttaatagt
     2461 atttctacaa tggaaggtgt ttcagaagct atatcagagg aaattcaaag ttacgtttat
     2521 gaaattataa ttagagacga tgtttattct tcccctacag gaatagttat agcaggatat
     2581 ggaagaatgg atattttccc taaactatat tcttataata tgtttggatt tgttatgaat
     2641 attctgaaat actcagaata tgaaagtgct caaataggaa atgacaatgg ttcattaaga
     2701 tctactatat taccatttgc tcagtctgat gtggtaaata ctgtagttca aggggtagat
     2761 ccacaaatta ctaattatct gtcgagtcaa gtcgatagtt ttgacgataa cggaaaaaat
     2821 acctatatta atattataaa gaatatttca gagtttcaac aaaatcaatt catatttccg
     2881 ttactaaaca tgattgcttt actcccagtt gaagaaacag caattatcgc agagacttta
     2941 ttaaatttaa ccagttttaa acgaaaatat actacttctg tagaaacagt aggtggccca
     3001 attgatgttt tagctattac acctaatgat ggccctattt ggattaaaag aaaacattat
     3061 tttgatattg ataataatat tggatacaga ttgcgaaagg agagagcgaa tgattacaat
     3121 aattaaacct caggaaaaat cccctgtttt gaaatttaat gagagcaatc tagcccataa
     3181 taaaatgagt ataactgata cagtatttga tgtaatggtt gagcaacaaa aaaaaattaa
     3241 taataacaat agacaaagaa aagaaattaa ccaatattaa tgttttttct gttgcgtttt
     3301 ttgcagtcat aatttaaaac ctcgctcaat cttgggcgag gtcttttttt atttttctga
     3361 aaagttaaag taaataatag cataaaataa tatattttac aaagaataag tacaatctag
     3421 ttttttgcta ttaaatgtgt aataataaat atgccatcac aacatgaaga atgaaatcca
     3481 ttattatcta gtctagtcca ttctttttgt ttgcagtatt tgtgatggct ttccgtaccc
     3541 ttagctcagt tggtcagagc agacggctca taaccgtccg gtcgtaggtt cgagtcctac
     3601 agggtacatt aacgtagcca tttgaatcgt tctgtgttag aattttttga agagtattat
     3661 acaagctaaa gcttttcttc attgccactc aaatgagtgg cttttttatg tatcctttta
     3721 tggattaatg aaaggatgtt tcacatagtt atatttctgt atatttgaaa agttttactt
     3781 tgatttttaa atagaaagac atttgggtta aattgtgaga taataataaa gaagagttta
     3841 aagcgcacct caaaccactt ccccataagt gtgttacgct ttaaactctt ttatatttga
     3901 agctattaaa aggcatacca tatttttgaa aaaaagtgag aaaaaaggct tacaattgga
     3961 gtggtagtta attagtgact tatttttgat tttatagcac tgatactata aaatatagat
     4021 atcatcatat tacacaatct taatactaac ttaaaaaata tctcctttca caagtatggt
     4081 gataaaattc gttccgggct acctttttag gtagcctact ttaatcttta tacctttctg
     4141 gatcaacgaa agtatacttt atatagtcat aacgccgatg atcgctacgt gcgtccggca
     4201 cgtcagtcac gatatcaaac aaaaagtata catctttctt cattctagtt tttgcagcag
     4261 ggattttaaa gtagttctta ttagaatagt agagattgat taataagcta tcttcgattg
     4321 ctagaaagaa aacttctgaa tcccacacct tataaaaatc tttgataaat ctattcgaag
     4381 gatcaaattt aaaccataat tgtgtctttc cttctattaa aatatcttga aatttactct
     4441 gttaaaaaaa ataaattaat tggtgaaaat gattctccaa taaaaacacc tattgagcta
     4501 agcttaagaa atcggatggg aatactccaa agatcggaaa tagtaaaaga acttttttat
     4561 cataaattta gttatgaaat aagactagat gatacttatg agcattatag aattgttttt
     4621 ttcgtataca attctataga agatgctact gcgactactg cattaacatt cggttttacg
     4681 aaaaatggaa caatcaattc ggataaaacc cgtcaagctg ctacagaaag tgatgatata
     4741 tgtaagaaag tatgcaatgg ggaagagaat tactggatag gggaggaaaa gttgaatgaa
     4801 atctattaat gatttattaa aaaaacatcc tgatttatat aaaaaattaa attctgaaca
     4861 aagaaacctg tccaaacaat tacttaaaat aagattaaaa aaacaaaaaa acgtgacaga
     4921 attctcaaaa atgttaggaa taagtgaaaa aaaatatctt gaatttgagt tcggagatat
     4981 gcatattcct gttgcagagt acaataaact tttgaaacaa gttgaaaatt tgtcctataa
     5041 agattcaatg aatttcacta ttaaggttgc tggcggccct attaaatatg accgtattga
     5101 aaataaacct tatattcgga ataaaagtta ctcagtattt aaaagtagaa agagaaaaga
     5161 agtatcgtca aatatggtct atgctagtgt taattaccaa gatacgagcc gctatattgt
     5221 agaaaaagag gtatatgtac atggataaag gaaatagtgt tacttttgca cttgaaaata
     5281 ttagtttgaa taaaattcat tttgaattaa ctgataattt tagttatgga gatttagagt
     5341 ttaatattga acttggatat aaagaagacg aagcagagta tctagaaaaa aaacttgttt
     5401 ctttacgagc tcacattgta ggggggatgg aaggagcacc ggtagatatt ttactctttt
     5461 cagttattcg tgtttctaca aatgaacagc catataaaaa attagtagaa gaatctatgg
     5521 gagagctagc taaacctatc ctgaataaag cttctaattt gatttctaat ttatatagcg
     5581 aagtaggagt tatgcctaca gttattgatt tatatcagct atatagtcaa caaaaataaa
     5641 atacaagtaa tagagttatc tatttaaatt tgcaagacaa agacctcaac cagtcatcct
     5701 tggttgaggc ttttttgctc tgtaattaac tcgtatagat cctgcaagat agtttgtttc
     5761 tgaataaatg attgatatga agtatttaga tgactgtatt gacaactata aaaatcattc
     5821 gataaaatag tgatgttatc gcatatcttc actatcaccc ataatagtca cactccaagc
     5881 tatgcgataa caggtttgtt gccacacatt ctactggttg attgtttatg gctttatgtg
     5941 gcaacaacca gtacccttag cttagttggt cagagcagac ggctcataac cgtccggtcg
     6001 taggttcgag tcctacaggg tacataattt aatctatttg ataaaaaata aaattcaata
     6061 atggtataat aaaatatcgg ctcgtcgctt ccacagagat tttcgtggga ggaggtgtat
     6121 gatttgtttg aattcacttt ggagcacgtg ctcttgccat tgttaattgg tttaactttg
     6181 gcattattta gtcattggct agataaacat tagagccgac aatggcgctt actgtttcgc
     6241 agcggtaagc gtcttttttt gaaaaagaaa aaaacacaac gtattcgcag gtacgttgtg
     6301 tttatggtgt atatttgttt aaattcactt tcaattatta ttatacttgt taaataaatt
     6361 gtgtcaatat aaaagatatt tttatacgtg tactaaccta tattatcctt ctggtaatgt
     6421 tattccatcg cagcaggata tgaattttac caaaaggata caaaagtgtg gagaaatgat
     6481 ggggatcact gtactggacc acttgatcat cggacgcaaa cgatatttta gtttgagaga
     6541 agaaggaatg atggaagaga agtaagttgc tttcttgcaa aaaaaatgaa gcaagtgtac
     6601 aattatattg taattttgtt tgggaataga agttgaaaca tctgttgcac ctctatcgta
     6661 cacgagcaat gttacaattt aaattagtgc ttttggcacg aggaggatat tattatggaa
     6721 aacggaacag taaaatggtt caacgctgaa aaaggatttg gatttatctc acgtgaagat
     6781 ggaagcgacg tattcgttca cttctcagct atccaaggtg acggattcaa aacattagaa
     6841 gaaggtcaag cagtgacttt cgacgttgaa gaatcagacc gcggcccaca agctgcaaac
     6901 gttgtaaaag cttaatttta tctgtaaatc aaattgatgg tagacatcaa tttttacgag
     6961 agaacaaagc gagtaacaaa aatacctgcc acaagagaca atttctcttg tggcaggtat
     7021 ttttttgtat gaaaaagtaa ataaatttaa gaggctatga aagagccacc ttgtatcaag
     7081 gaataagaac aaacaaaaat ggcttctcat gtttttcatt tgttttctct tatattcagg
     7141 acaaggtgct gatttcataa cctcttattt attcttcatc tggtgtcatt accattggca
     7201 aaatcattgg atgtctttct gtacgttcga ataagaaagg ctgaagcgcg ccagtcatcg
     7261 cttctttcaa tttatattct gaacagtcag gtccattcaa acattctctt aaagcgtgga
     7321 ataagattcg ctgagcttca ttgatcattt ctcctgattc tcgcatgtag acaaatccac
     7381 gagagagaat atctggacca gccaagattt cttttttctt gatatccact gtcgcgacag
     7441 ctaatacaag accttcttct gaaagcaggt gacggtcacg taaaacgaca ttaccaatat
     7501 caccgatccc gctaccatcg atatacacat ctccagccac aaaatgccca gcaggacgcg
     7561 cagaatcgct agttaacgct aaaacatcgc cattttccat gatgaagcag ttttctgcag
     7621 gaacacctac atcttgtgct agagaagcat gtactttcaa catgcggaat tctccgtgga
     7681 caggaataaa atattttggc ttcatcaaac gaagcattaa tttttgttct tcttgtccac
     7741 cgtgaccgga agtatggatg ttattgattt ttccgtgaat cacttctgca ccagcttcag
     7801 acagcaaatt gatcaaatga ttgacacttg ttgtattacc aggaataggt gaacttgaaa
     7861 agatcactgt atcgtctggc tggatttgga tttgacggtg agtaccattc gcgatgcggc
     7921 tcaacgcggc catcgcttct ccttgagaac ctgtacatag gatcatcgtt tcattggcag
     7981 gcaagcgatt gatttcgtgt gcatctacaa atgtgccgtc tggaactttg atatatccta
     8041 aacgttgacc gttgacgatg gcattttcca tgcttcgtcc gaaaacagcg attttacgac
     8101 cagttgccac agcggcatct gctgcttgct gcaaacggaa gatgttagaa gcaaagctgg
     8161 caaaaatgat acgtccttcg atttttgaaa agatcttcaa aatagaatgc ccaatcgttt
     8221 tttctgattt agtaaatgtt ggaatctcag catttgtact atcagataaa aggcacaaga
     8281 ctccttcttc cccgatacga gccattttat gcaagtttgc tggttcgcca acaggagtga
     8341 aatcgaattt gaagtctcca gtcgctacga tatttccaga aggtgttttc accacgatcc
     8401 ctaatgcatc tgggatacta tgggtcgttc tgaaaaagct gacagaagtc tttctaaaac
     8461 ggatgatcgt atcttcattg atctcatgga gctctgcatc tcgaagcaag ccatgctcat
     8521 ctaatttgtt tgtgatcaac gctaatgcga gaggaccagc atagatagga atatttgctt
     8581 gtttcagcaa gtagggtatt ccgccgatgt ggtcttcgtg cccgtgagta atcaccaagg
     8641 cttttacttt gtgtaagttt tgtatgatgt agctgtagtc gggaatgaca tagtcaattc
     8701 caagtaaatc gtcttccggg aatttgatcc cggcatcaat caaaatgatt tcatcttgga
     8761 attgtacccc atacgtattt ttcccgattt cacctaatcc accaatagca aagacgcctg
     8821 tctcgttatt tttgatggaa agtttcatat taaaactcca ctaatgagaa atcagcattt
     8881 tctttttcgt actctagatg acttccttct agaagttgaa cgaattcaat attgtatggg
     8941 gtattttctt ccacacgttg gcgagcgtct acatcgcttt ttgcctcaat gtaaagagat
     9001 tttgtttctt cccgtttagg gttgcgtact tttgtttctt gataataaac tttatagatc
     9061 attgttttgt ctcctttatc tgcgtaaagc agtgatttag ctagttgatt tttttagaca
     9121 acacaaaacg aggggacaag ccacctggtt tttcatatgc tttgactaga atactggatt
     9181 cgagtcaaag agacaagcct cgtttttgct tatctgttcg gatatttttt caaccgtacc
     9241 ttctgtataa aaaatataca acaattaatt gttattctag cataaaacag caaataagta
     9301 tagaaatcaa ctagattgaa agaaaaaatc aatgtttatc atcccgctat aatcataatg
     9361 acttttttat gagagaagtg ttctattaat aggctcgttg tgctatcatt tttagtaatg
     9421 aaaatgtaac aaaagattaa aaggagatga gaaagtgaaa ctaatgtggc attataccat
     9481 gcgttataag aaattcttgt ttttcaattt catatgcgta tttggtttta ttttgattga
     9541 attaggactt cctacgattt tagcacgtat gatcgatgta ggaatccgca atgatgattt
     9601 tgattatgtg aagcaacaag ggatatttat gatcgttatt actgtaatcg gtattatttt
     9661 gaatatcttg ttaggttatt ttggttcgag gattacgact aatatcgtag cagatattcg
     9721 agatgatttg ttcgaaaaga tccaaagtta ttcgcatcag gaatacgaaa atctaggcgt
     9781 atcttcattg atcactcgta caacaaacga tgcttatcag atcatgttgt tcctgcaaaa
     9841 tattttacgt atcggtttta tggcaccaat gatgttcatt gtcagtttgt acatggtcat
     9901 gcgtacaagt gtgacactca gtttgtatgt agtaggtgca ttacctttac tattattggc
     9961 agtcgtagcg attgctaagg tgtctgaacc gttatctaaa aagcaacaaa aaaacttaga
    10021 taaaatcaac agtatcttgc gggaaaatct ttcaggattg cgtgtgattc gtgcattcgt
    10081 caatgaaaag tttgaagaaa aacgttttgc tgtagtcaat gagaattatg cttctagttc
    10141 aaaaagctta ttccgtttga tggctgttgc acaaccgggt ttttatttct tatttaatat
    10201 cgtaatggta ttgatcatct ggagcggggc agtgcaaatc gatgcaggcg agcttcgtgt
    10261 aggagatttg attgcgttta tcgagtatat attccatgcc ttgttctcat tcatgttatt
    10321 tgctagtgtg ttcatgatgt atccaagagc agctgtttca gctggacgta tccaagaagc
    10381 cctagatgcc aaaccttcga ttgtagaaga tccaaatggt atatctgata caaaaactaa
    10441 agggtatatc gaatttcaaa atgtaacatt tgcttatcca ggccattcgc aagagccagt
    10501 gatacgaaat gtcagtttta cagcctctcc aggagagacc gttgctttta ttggaagtac
    10561 cggtagcgga aaatctacgt tgatccaatt gatccctcgc ttttatgatg tgagtgaagg
    10621 aaagatcttg atcgatggag tagacgtgag agattatcgg ctaagcaagt tgcgagataa
    10681 gattgggttt attccgcaaa aagcgctgct atttactgga acgattgcag ataatttgcg
    10741 atacgggaaa gaagatgcta cgcaagaaga aatggaacgt gcagctgaga ttgctcaagc
    10801 ttcagaattc atttctcgaa aaccagatgg atttaatgaa catttatcag aaggtggttc
    10861 caatttttca ggtggacaaa aacaacgatt ggcaatagcc agagccatca tacgccgtcc
    10921 ggaaatctat atttttgatg acagcttttc tgcattagat tatcaaacgg atgcgaagtt
    10981 acgtgctcgt ctgaaaaaag aaacgacaga atctactgta ttgatcgtag cacaacgtgt
    11041 gggaacgatc atgcatgcag ataagatcat cgtattaaat gaaggagaag tcgtcggtat
    11101 ggggacgcat cgggagttgt tggaaaaatg cccgatttat tatgatattg ccgcttctca
    11161 attatcaaag gaggaattag catgaaaaaa accttttctt ccttaaaacg tttagctcga
    11221 tatatcagac cgtatcgtga gacttttctt ttagtgatcc tatttacagt tctgacagtg
    11281 gctttcaacg tggctttgcc atatgttaca ggacttccta ctacagaaat cagccgtaat
    11341 attgccaatg gcgaatcaat caatttttct tatatattca aatgtctcat ttggatcaca
    11401 gttgttggaa tagggtattg tatttcgcaa ttactttctg gtgttttgat gacaaatgtc
    11461 gttcaaagtg ccatgcatga tttgagaaga gacatagaag aaaaaatcaa tcgtcttccg
    11521 gtttcatatt tcgataaaaa ccagcaagga aatattttgt ctcgtgtgac gaatgatgta
    11581 gatgcagtca gcggtgcttt acaacaagct tttattggta tcgtaaatgc gatattggga
    11641 attacgttgg ctgcagcaat gatgttttat atccagccga tgatggcgct gatctctatg
    11701 atcatgattc caacatcgat ctggatctca aaacgagtga tcaatgcttc gcagaaatat
    11761 tttcaaagca tgcagaattc tcttggtgag ctaaacggct acgtccaaga aaatatgaca
    11821 ggttttagtg tattgaaagt atatggacgc gaaaaagaaa cattggaagg attcaaaaaa
    11881 gttaatcaca gcttgaaata ctttgggttt cgtgcagcat tcatttctgg cttgatgatg
    11941 cctctagttc aattaactgc ctatgctact tatattggta tggctgttct aggaagcttt
    12001 tatgttatta ctggggcgat cgttgtcggt caactacaag cattcatcca atatatttgg
    12061 caaatcagtc agccaatggg gaacgtgaca caattgtctt cagttttgca aagtgcatca
    12121 gcggcaacga aacgtgtatt cgagatttta gatgagccag aagaaaaaga aaacaaagta
    12181 gatgcttcac tgccagaaac gattttagga gatgtgacat tcgatcatgt cgattttgca
    12241 tatgatccga agaaaccatt aatccaagat ttgaattttg aagtgaaagc tggtcaaacc
    12301 gtagctgtgg tcggtccgac cggtgccggc aagacgacat tgatcaatct attgatgcgt
    12361 ttttatgacg tagacaaagg agcaataagg attgatggaa tcgacaccaa atcaatgagt
    12421 cgcagtgatg tgcgttcgct atttggtatg gtcttgcaag atgcatggct ttatcaagga
    12481 acgattgcag ataatatccg cttcggaaag cttgatgcga cagattatga agtagttgat
    12541 gctgcgaaaa cagcaaacgt agatcatttt atccgaacga tgccagatgg atatgatatg
    12601 gccatcaatt ctgagggaga caatgtgtct ttaggacaaa aacagttgct gacgattgcc
    12661 cgagcagtgg tctccgatcc taaaatcttg attttagatg aagcaacaag ttcagtagac
    12721 acccgtttag aagcgttgat tcaaaaagca atggatcgcg tgatggaggg acggacaagt
    12781 ttcgtcatcg ctcaccgttt atcgacaatc cgtgatgcag atctgattct agtgatggat
    12841 caaggtcaga tcattgaaaa aggaacgcat gagagtttat tggcacaagg tggattttat
    12901 gaaaaactgt ataacagcca atttgctgag gaagcagaat aagtcatata agaataaaac
    12961 agtttaaaac ttattttttg ttctctattc ttgataatgg taaagtaaag ttatcaagaa
    13021 aagtgaggac acggagatgg aacagttttt aaatgaaaaa attactgaag ccaaaagaga
    13081 agttgatcgt ttaacgcacg tctgtcagac gaagcctttt gattcagctg atttttttga
    13141 aaatgagttt caaatcgaac gcttggcagc acaaatagaa gtgtacgaat taattttaaa
    13201 aaaagtaata gaagaaaata tagatgtaca ataaaaacag gtaaaacgtc agttaccaga
    13261 tactgtaaat agacatctgg cctgagcagg ttttacctgt tttttttctt atgaaataaa
    13321 tatatgctat gataccttta ttcaatagga ttagtttcta caaaaaatga aaggagaaaa
    13381 ataaatatgg aacggtttat agcatcaaat gccacagtga ttggtgatgt gacattgtca
    13441 gaagatgtga cgatctggta tcaagctgtt ttacgcgggg acagtaattg gataaaaata
    13501 ggacaaagaa cgaatatcca agatggtaca atcatccatg tcgatcatga tgcacctgta
    13561 gatattgcgg agaatgtgac ggtaggacat cagtgcatgc tacatggctg tacaatcgaa
    13621 aaaggggcgc tgatcgggat ggggaccacg atattgaatc atgcggttat tggtgagaat
    13681 agtttgattg gtgctggatc attagtaaca gaaggaaaag ttattcctcc taatgtcttg
    13741 gcttttggtc gcccagctaa agtgatccgt cctttgacaa aagaagaaat acaaaaaaac
    13801 aaagaaaaca tccagcatta tgtcgagata ggtcggatgc atgcgcaagg aaaattcaag
    13861 gagcaaagat aggcagtagc atccataaaa taaaaaagga tggtcagttt gagttgacca
    13921 tcctttttta tttggtttag ataagagagc ttaaaaaagc ttcctttgaa acagattaat
    13981 ttaatgaaga actgttttcc atgacttcat cgatcaatcc atatgctttt gcttgttcag
    14041 ctgtcatata gttgtcacga tctgtatctt tttcaatcac ttcaagcggt tgtccagtgc
    14101 gttcagctaa aattttgttt aagcgttcgc gtgtttgcaa aatatggcgt gccgcaattt
    14161 cgatttcagt tgcttgccct tgagcgccgc caagaggttg atggatcatg atctcagcat
    14221 ttggtaaagc aaatcgttta ccttttgtac cagctgtcag caagaagctt cccattgaag
    14281 cagccatacc cataacaatt gtttggacat ctgctttgac aaagttcatt gtgtcgtaaa
    14341 tagccatacc tgctgtaact gaaccaccag gagaattgat ataaagatag atatcttttt
    14401 cagaatcttg agcgtctaag aaaagcaatt gggcgatgat cgaattagca agatcatctg
    14461 ttacttggcc gcttaacatg atgatacggt ctttcaataa acgtgagtag atatcgtaag
    14521 ctctttcacc tcgtgaagat tgttcaatga ctgtaggaat taaattcata atagagttcc
    14581 tccttgattt cgtttagaaa tagtgtacca taatttagtt tctaatacct aaaatgtagt
    14641 atacattttt ggtcaaaaaa ggtcaaataa aaaacttagg caaattagtc gcataaaccc
    14701 gctttatggt atgataagca gagaaacaaa acaaggagga acaacagatt gatagttggt
    14761 attactggcc ttatcggagt gctgacaggt gctgtagttg tctatatcgg catgatactg
    14821 caaatgcgtc acttggaaaa taaagaacag cgtagacgtg aattggaatt gaaagtcaaa
    14881 gaaatcgaga cgctgaatca attaaataaa aagatcaacg agatcttgca aaaacggaca
    14941 acgctgatgg aagaatatgt cagctttgat gcatttgatg attgttatat cacgattgac
    15001 gattttgcgt atctccaatc attttcagcg caaaatagtt tttatctgcc aaattatatt
    15061 ttagacgagc tatttaagaa tatctcccat cgaaaagtga ttttatctcc agatgaaaca
    15121 atgaagattg gtggatatgc ttataaaggc ggacgcgtga ttttagagaa ttttacggat
    15181 agtctgactg aaatgatcaa tgaaaaaaaa gctcagttga agactatgac gcgccagccg
    15241 attggtttct tctcgaaaga tgatgtttgg agctgatatt ttgaagcatt gccgttgcac
    15301 atgagagcgt ggtaatgctt tctttttttc ttaatgatac aatagaactg aacggagtga
    15361 agaaagatgt tacaaatcta tgcccatcgc ggaagcagcg gcacccaccc agaaaatacg
    15421 cttcctgcat ttgcagaagc tgtacgagta ggtgcagatg gtatcgaact agatgtccat
    15481 ctaagcaaag atggttattt gatcgttatg cacgacgaag aagtggaccg gacgactaac
    15541 ggtaaagggc tgattcgaga aaaaacattg gaagaactca aaaaattgaa tgcagggggc
    15601 aaattcagca aagaatttcc agcagctaaa gttcctgaat tgagagaagt gttaggactg
    15661 ctcctccaaa aaaattaccg agggatgcta atgattgaaa ttaaaactga tcagtatgaa
    15721 tatcccggta tcgaagaaaa attagccgaa acattaaaaa gtagagattg gccttttcaa
    15781 catgcatatt gcagctttca tttggattct ttggaaaaaa tcgcattact ggaaccggag
    15841 atacagctgg acttattgat gagtacttct gataaaaaga tccaactagc agcagaaacc
    15901 ccttatatag aaggagtaca tccaaaaaat acttggttgt tcgaacatcc agtccaggca
    15961 gctgattttc caaaagcaat tcgtgcatgg acgattaacg atgaagaaga aatggccaaa
    16021 tgtcaagaac tcaaaataga tggaataata actgattttc cggagaaagc tcttcggtgg
    16081 aaacaatcaa cgaaaagtag gtaaaatatg gaaaaagtat tagtgatcgt cggtccgaca
    16141 gcagtcggta aaacagcgct aagtgtggaa ctcgcacaac tatttggagg agagatcatc
    16201 agtggtgatt cattgcaaat ctataaaaat ctggatatcg gtacagcaaa aatcaaagaa
    16261 gaagagatga ataatgttcc gcatcatttg attgatgtga tcgaacctac tcaacgttac
    16321 tcagccgctg attttcagca ttcaggtcga caattgatta ccgagattgc gaaccgaggg
    16381 cacctaccta tcatagctgg tggtacgggt ctctatatcc aatcccttct atatgattat
    16441 cagttaggag cgacagaaga agcgaatcct gagattagaa aaaagtatga aacgttagct
    16501 gaaacaattg gttcccaagc attatggaat cagttgaaag aaaaagaccc ggcagctgct
    16561 gagaaaatcc actggaacaa tcaacgcaaa gtgataagag ctctggaagt tttagagacg
    16621 acaggacata gtatcacggc acctaaagaa gagccaaagc aattgtatga ttacctcatg
    16681 attggattag atacgaagcg tagtattctt tatgaacgaa tcaatcaaag agtcgatttg
    16741 atgctagcag aaggtttagt agcagaagcg cgtaaggtgt atgagcttgg agaagtccag
    16801 gccagtcaag gtattggata taaagaattt ttcccttatt ttgaagggaa agaaacattg
    16861 gaagaagcaa cagaacaagt caaactacat tcgagaagat acgcgaaacg tcagttgacg
    16921 tggtttcgta accgtttgga tgcacagtgg tttgatctta taagtgagcc aaatcaaaaa
    16981 agtcagattg agcaaacaat caaaaaatgg ctggaggcgg aataaaatgg aagaaaaagt
    17041 gatcatcgta ggggtagaaa ccgaagcaaa ccagcgttac ttttcagagt caatggaaga
    17101 gctagttcag ctgacgaata ccgcatcagg agaagtcgta ttcacaatta cacaaaagag
    17161 accacaagtg gatcggcaaa cgattatcgg taaagggaaa ttacaagaat tagttcaaca
    17221 agcggatgcg catgaagcgg atttgatcat ctttaatcat gagctaactc cgagacagag
    17281 ccaactgatt accgatgctg ttggtcttcc ggtaattgat cgcgtgcagc ttatcttaga
    17341 tatttttgcg atgcgtgctc gttcgaaaga agggaagctg caggttgaac ttgctcagtt
    17401 agaatacctg ctgcctcgtt tagtagggca agggaaaaca ttatctcgtc ttggcggtgg
    17461 gatcggaaca agagggccag gtgaaacaaa gttagaaaca gaccgccgac atatacggaa
    17521 taaaattttt gctgttaaga aagaattgaa agaagtagaa gctcatcgag agcgcaatcg
    17581 ccaaaaaaga aaaaatagcg agatttttca gattggactt attggctaca cgaatgccgg
    17641 gaagtcaact atcttgaatc tattgacaca agcggatact tattcgaaag atcaattgtt
    17701 tgcaacgtta gatccattga ctaagagatg gcgttttgct gaaggatttg agattactgt
    17761 aacggatacc gtcgggttca tccaagacct gcctacgcaa ctgatcgatg ctttccattc
    17821 tacattagaa gaaagtcaaa atatggatct tttgctacat gtagtcgatg ctagttctcc
    17881 agatcgtatt ttacaggagc agactgtctt aaaattgatg gatgaactga atatgaaaga
    17941 aatgccgata ctgactgttt acaataaggc agaccagatc gacccagcga tgttcacgcc
    18001 tacgctattc ccaaatgtat tgatttctac tcagacgaaa gaaggtaaga tggcgttgat
    18061 cgaagcaatc aaacgtcagc tgatggaact aatgacccct tatacacttt ctgtgccaag
    18121 caacgaagga cagaaattaa gcgagttgag aagacaaaca atggttttgg acgaagcgta
    18181 catggaagaa acaaacgaat atgaagttaa agggtttgca aaaaccaatt caaaatggtt
    18241 aagaaaaaac caataaaatt ttattttttt aa
//
LOCUS       DASHWW010000056        18225 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.056, whole genome shotgun sequence.
ACCESSION   DASHWW010000056 DASHWW010000000
VERSION     DASHWW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.056"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..190)
                     /locus_tag="U2R64_002082"
     CDS             complement(<1..190)
                     /locus_tag="U2R64_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918878.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="U2R64_002083"
     CDS             complement(200..1015)
                     /locus_tag="U2R64_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8918879.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="U2R64_002084"
     CDS             complement(1277..1720)
                     /locus_tag="U2R64_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HEM8918880.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="U2R64_002085"
     CDS             complement(1854..2192)
                     /locus_tag="U2R64_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8918881.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="U2R64_002086"
     CDS             complement(2180..2557)
                     /locus_tag="U2R64_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8918882.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="U2R64_002087"
     CDS             2781..3974
                     /locus_tag="U2R64_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8918883.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="U2R64_002088"
     CDS             complement(4140..4562)
                     /locus_tag="U2R64_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918884.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="U2R64_002089"
     CDS             4957..5151
                     /locus_tag="U2R64_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918885.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5642
                     /locus_tag="U2R64_002090"
     CDS             5148..5642
                     /locus_tag="U2R64_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918886.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5804..6976)
                     /locus_tag="U2R64_002091"
     CDS             complement(5804..6976)
                     /locus_tag="U2R64_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8918887.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="U2R64_002092"
     CDS             complement(7182..7997)
                     /locus_tag="U2R64_002092"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8918888.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="U2R64_002093"
     CDS             complement(8147..8593)
                     /locus_tag="U2R64_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEM8918889.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="U2R64_002094"
     CDS             complement(8590..9594)
                     /locus_tag="U2R64_002094"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8918890.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="U2R64_002095"
     CDS             complement(9634..9963)
                     /locus_tag="U2R64_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEM8918891.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="U2R64_002096"
     CDS             complement(10089..12416)
                     /locus_tag="U2R64_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8918892.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(13259..13552)
                     /locus_tag="U2R64_002097"
     CDS             complement(13259..13552)
                     /locus_tag="U2R64_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HEM8918893.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13955..15133)
                     /locus_tag="U2R64_002098"
     CDS             complement(13955..15133)
                     /locus_tag="U2R64_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8918894.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(15237..15551)
                     /locus_tag="U2R64_002099"
     CDS             complement(15237..15551)
                     /locus_tag="U2R64_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918895.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            15658..15873
                     /locus_tag="U2R64_002100"
     CDS             15658..15873
                     /locus_tag="U2R64_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918896.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(16173..16415)
                     /locus_tag="U2R64_002101"
     CDS             complement(16173..16415)
                     /locus_tag="U2R64_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8918897.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(16402..16830)
                     /locus_tag="U2R64_002102"
     CDS             complement(16402..16830)
                     /locus_tag="U2R64_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8918898.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            complement(16982..>18225)
                     /locus_tag="U2R64_002103"
     CDS             complement(16982..>18225)
                     /locus_tag="U2R64_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEM8918899.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT         5296 a         3556 c         3175 g         6198 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag cgaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttttgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcatgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aaaaatcatc aaataatcct ttacacgtta ttctaaattt aatttttatt
    12481 attttattga tgtatagaaa gtttggggct ttttttctct ttttattcta aggttatttt
    12541 agtcttgtcc tttaatacaa agattttatt tttaaataaa aaatactctt tttttacgat
    12601 tattgaaaaa aaaagataaa acttgattaa ttgaagtatt gcttaaattt ggaagctatg
    12661 agggaagaat aaaagagtta ggacgggatt atctactatt tttctttgtt ttaaatattt
    12721 gttatctttg aacataaaag agaaatgtgt cgactgcagt gttgtgtccc tcatcacgaa
    12781 taaacggtgt tcaattagct gatcttgtat tcacttaaaa aatggtaaag tacgagttgc
    12841 tattccccat tttcaatttt ctaacgctca ggacaaaata ctgttttcac aacctcattg
    12901 gaataaaagc atatatattg tttcaagaac gaaatcttgt tatcttttta aagggcatct
    12961 gtccaaaatc taattttagg aggtacgttt tggtatttat tcgtacaaat aaaagagaat
    13021 tatctttatt catgtaacgc atccaattga ttttttcatg tacgctcctg gaacgatttt
    13081 actgacgatt gcttatttaa ctgcgaatcg ctcattagct tttatcatag ctatccatat
    13141 tttgaataac gttcttggct ttgtattata gatacagatg acaaaaaaag ttcaagtatg
    13201 cggtgtagaa ccaatatcgc atacttgaac ttttttcaat gagtataaat taaaacttct
    13261 aattttcaat tcccatcatc tgatatgccc gaccgtctga acttcttttg aaaaagccaa
    13321 atgtgattag ataacgtctt tgttcgacat aatcgccact agaaaatacg ttcagcagta
    13381 tcgaattaac ctctgtttct gtataagtca ctccatggtc aaagcgtttc aagacttctt
    13441 tcaataggat gtatttcttt tttgttgaac ttggtacttg ttttactttt ccatcattca
    13501 tgaatgtgtc taaaactttc atcttttctt gctccgtata agtataaacc atcttctttc
    13561 tccttttgat tctaagaata ctccatttat gttagaatat tctggatttt ttattaaagc
    13621 ggttactctt aagaaagata ttatcatagt gctctttttt ttactactac ttataggtag
    13681 atttattcta atccattatt ctcccctacc aataattaaa gaaaaaactg gatcagggtg
    13741 ttcaaattac atgctaagaa aaaagaaccc ttgaatacca agggttcttt ctcagtctga
    13801 taacaatgat taacgacgga tttctttgat acttgtgaaa agtcgttaaa gtattgatat
    13861 aaaaggattt ttattacctc tgactacata ttgactaatt tgttaaaaaa tcgtttttca
    13921 agaatcctgt aataccagtg ctttcaccgt ttttttaact ctctaaagaa ctaaaagcaa
    13981 tcagaggttt taccttttca tttgacgtta agtggcgata aattttcgaa gttgtttggt
    14041 cagtatggcc taagcgatct ttcaagactt cccagctaca gtgttccgct actaagcttg
    14101 ccattgtatg acgagctaaa tgagtatgaa atggcttatt aattcctgag cgattcacgc
    14161 accgtttgac gtgatcattt acatactctc gacgataagg aacaccacgt ttactagaat
    14221 caagatacac aaacaaatat gtttcttcta taataaacct gtaatgttgc ctcatctcac
    14281 ccaaagcctt aatcaactgt tgtagctttt ccataactag aggagttact agaactcgtc
    14341 tagcagaact aactgtctta gtagtttcaa ttcgaaaatc cttactctta cctttaactg
    14401 ccgtttgctt atagaacaga atttcatttc ttttgaaatc tatatctcca ggctgtagag
    14461 caagcgcctc gctgactcgg cagccagtgt aaaatagaac atggaaaagt acagacatcg
    14521 gtaattcctc atgaacaatg ccataattca aaaaagttct caattcatcg acagtaagaa
    14581 acttgtcctc aatattattt atggcttctt ttaaatcagt taccgttaac tgatattttg
    14641 gcattctcac agacttcatt ggattttcac ttatcaaatt ctttctttga caatatttaa
    14701 aaatcatatt tagaacttga ataagtgatt gtaaactatt tttggcatag ccaacatttg
    14761 ttccattaac gccacattcc tttaaggtaa aaagcaattc ttgaaggcac tctggtgtca
    14821 aatcagacaa ctttttatca ccaatccatc gaacaataat ttttaattgt tcctctcgct
    14881 tatcataggt tatttccttt tgttcattta acgaacggta atattggaac cattgctcac
    14941 ctacaacact aaacttgtca ttgcttgcaa caattttttt cttaagcctt tgttgtttct
    15001 ccatttccag ataagcgagt tgcgcctcac gttttgaatt aaagccacgt cttgttgttc
    15061 gatatgcttg aaagtaccat gtgatcctac cagtagaact gatttgcttc ttgaatcgat
    15121 ctgttttttc catttattga ttcctcctat tttgaaggaa cccaacaagc agaaaccctt
    15181 tggaaatctt tctatctatg tcatcattgt accgcatctt agaaagaaaa tgtaacttat
    15241 aaagatcgaa gtagtcgcaa tttttctcga tagtcattcg aatcactctt tctcatccat
    15301 tctaaaacat catcacgaaa atagtgtcct cgaatcccgt accaacaggg aggaaactca
    15361 ccaagtttta ctaaacggtt cagtgtacta tcacttatct gaaatagtcg ctttaaatca
    15421 gtatttgtta ataccagagg taaatgactg actgcaagca atttttccgt gtaatcttcc
    15481 agtttttttt gtaaaattga atagaactct atttccagag aattaacatt tgttttaact
    15541 tccaactcca tcacccttct ctctcaaaat caaaacgacc accacggtac cccttaaaat
    15601 tgtaaaaaaa cactccagta ctccatcaaa acggactaga aaagaggaat ttttaatatg
    15661 aaacaaggaa ttgcagacat aaaaataatt aaagaaattc ttgaaaaatc tacggctaat
    15721 gcaatagcat tcggaacagg aatcaacttg agtacagtaa aaaaacttaa aagtggagag
    15781 agagctgaag aaaaattaaa tcttgccgat gctattaaaa tcacagaatt tggcatgaaa
    15841 aatatgccaa ccaaaatcga aatatggaaa tagtagtttt tctgatctat cagctgtttt
    15901 gccaaagcac ataggaatct cacctccccc cagtaatggc gggccgattt ggttacggaa
    15961 gtatcattat cgtagtcgcg attctcatat taaaatttgt cgcttaaaag ctaaccttgt
    16021 catggcgtaa ctagagaatc aaaatctaca tgtactgata gatttgctat tcatttgtca
    16081 aagagcgcta ggctattttc agcctatgga aatcctttat tttgacccga taaaaaactt
    16141 ccatagaatg aaaaggaaag ggaaaaaata ctttaacgag ttgtatcaaa ttcaagtatc
    16201 ttctcaatca attttgtttc cagttgtcta cgcatatatt catctacata cataaccatt
    16261 cctttttctt cttcataaac tggtttcatg gctaaccgtg aaatataatt ttgatatttt
    16321 gacagaacga tggacatggc aattgaatca ccagaagctg cggctttgat tgtcgttagt
    16381 ggtatgaatg gtatatatcg tttattttgc ttcatatttg acacccaaat actttcctag
    16441 ctcttccaaa gccatttgtc gttggtacca aacactgccg agacttttcc caataatatc
    16501 gccaatttca cgatcattaa gaccgatgag gaaggacata aaaatgattt cttgtctttg
    16561 actaggtaat gctgcaatcg catttgccaa ctcctcattg gaaataaaga ttttcatacc
    16621 aaggacaata aaagtaccac tactattcaa atttggttcc aaataataga actctgtacc
    16681 taaccctttt tgttccaata tttccattga tatttgccgt tggcgaaatc tagcgtactt
    16741 cttttgaata tttaacgcct cattgcagac tactttctta caaaaactgt caaacgtatg
    16801 ttgaatgtgg gtttcctctg agtcgcccat aatattctcc ccctcaaaaa attcattcaa
    16861 ctcgttttac ttctatccct ttccattatt actacaatct aggaggtaag cgccccatag
    16921 aacagtacct gtacgtcaaa taacccgacc tatagaatag aatcgggaat gtttggcgtt
    16981 tttagttacg agaaaaatgt tgttgtacat ccttgttcca aggcaacagt tgatctaaag
    17041 tttctgctga aagtacggga agatttggta tcttatcaaa tagaaactct agatacttta
    17101 caggattcaa tccgttaagt tctgctgttt tatatacact cagaatgatt cctgaagttc
    17161 gtgctccttc aagacttgtg gaatgcaacc aatttttccg tcctatcacc agctctttga
    17221 tatttcgctc cgcacgatta tttgtgagtt ctaaacgacc atcttcaaaa ataggttcaa
    17281 aaccacttcg tagtttacac gcatattgaa cggctgcatc caacttggat tttgcaacag
    17341 gatctatcgt tgccatccac tcataaaaag caataaataa tggacgcagt tcttgttgcc
    17401 gacagcttaa tcgcttctca ggagaaaagt ctttccattt cttttctagg acaaaccatt
    17461 tatccaattg tttgactgct tgagctgcgg gaatatccgt gtttttcttt ccttttggaa
    17521 ttgcttcgaa aaatttccgc cgaacatgcg cgaaacaata gacaagtcgt acactttcca
    17581 cggcattata cccgctatag ccgtcacagt gtaaataccc tgtaaactcc ttgagaaaag
    17641 ttttcggaac atctccagca cgactttcgt cgtggtgata ataaacgatg ggatgctgac
    17701 tgtcttttcc tgtacaaaac tgccagtaat aggtatctgt tttggcactt tcaatcacac
    17761 gataacttgt ttcatccccg tgtagaatct cttcttgatt aagatagact cttaatcgtt
    17821 ctcctaaagg gtctaacgcg ttttgcactg ctttaatatg ccaattggtg atattatctc
    17881 tcgaaatatc caacccatgt gtttgtttcc aatagttctc ttgccgatag gcaggaactt
    17941 tctgaccaaa tttcatccgg atcgtttccg ccactaaact attggaacct aagctattag
    18001 aaatcaaagg tttaggaacg atcgcttttt taaaagaaga aagtccttct ttttcgcagc
    18061 ttttacaaca ataggtatgt tgataatggg tgagacaatc caacatagcc tgatggaaac
    18121 gaatttcttc tcgtactttt gtccgtccga tatctttcat ctgtgaaccg caatgttcac
    18181 aaaattgttc ttccaaagga aggagatgtt ctttctctgt tatag
//
LOCUS       DASHWW010000057        17726 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.057, whole genome shotgun sequence.
ACCESSION   DASHWW010000057 DASHWW010000000
VERSION     DASHWW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.057"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            176..3343
                     /locus_tag="U2R64_002104"
     CDS             176..3343
                     /locus_tag="U2R64_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918900.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            3363..3908
                     /locus_tag="U2R64_002105"
     CDS             3363..3908
                     /locus_tag="U2R64_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HEM8918901.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            3936..4391
                     /locus_tag="U2R64_002106"
     CDS             3936..4391
                     /locus_tag="U2R64_002106"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HEM8918902.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            4388..5146
                     /locus_tag="U2R64_002107"
     CDS             4388..5146
                     /locus_tag="U2R64_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEM8918903.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(5232..5972)
                     /locus_tag="U2R64_002108"
     CDS             complement(5232..5972)
                     /locus_tag="U2R64_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8918904.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            6033..7286
                     /locus_tag="U2R64_002109"
     CDS             6033..7286
                     /locus_tag="U2R64_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEM8918905.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            7608..7835
                     /locus_tag="U2R64_002110"
     CDS             7608..7835
                     /locus_tag="U2R64_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEM8918906.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            7958..8284
                     /locus_tag="U2R64_002111"
     CDS             7958..8284
                     /locus_tag="U2R64_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEM8918907.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            8352..9065
                     /locus_tag="U2R64_002112"
     CDS             8352..9065
                     /locus_tag="U2R64_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEM8918908.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            9375..10226
                     /locus_tag="U2R64_002113"
     CDS             9375..10226
                     /locus_tag="U2R64_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8918909.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            10347..12212
                     /locus_tag="U2R64_002114"
     CDS             10347..12212
                     /locus_tag="U2R64_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8918910.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            12260..13669
                     /locus_tag="U2R64_002115"
     CDS             12260..13669
                     /locus_tag="U2R64_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEM8918911.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            13777..14478
                     /locus_tag="U2R64_002116"
     CDS             13777..14478
                     /locus_tag="U2R64_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8918912.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            14637..15116
                     /locus_tag="U2R64_002117"
                     /pseudo
     CDS             14637..15116
                     /locus_tag="U2R64_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            15964..16539
                     /locus_tag="U2R64_002118"
     CDS             15964..16539
                     /locus_tag="U2R64_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HEM8918913.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            16539..16979
                     /locus_tag="U2R64_002119"
     CDS             16539..16979
                     /locus_tag="U2R64_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEM8918914.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            16995..17696
                     /locus_tag="U2R64_002120"
     CDS             16995..17696
                     /locus_tag="U2R64_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEM8918915.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5965 a         2971 c         3811 g         4979 t
ORIGIN      
        1 gataagggac tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta
       61 cacctaatag aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga
      121 aatagattaa aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa
      181 tcaatgtgta aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac
      241 atccgttttt gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt
      301 tgacaagact actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga
      361 ggcttctact aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga
      421 acaaacgtct gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag
      481 cgaagctgcc acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat
      541 ccgactgatt cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat
      601 tgattttggt ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc
      661 tcagtcgatc gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc
      721 aaatatcgat ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata
      781 tcattttacg ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt
      841 aggactgatt tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga
      901 tgtccaacca gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag
      961 ctatcaattg aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta
     1021 cggttttcta gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat
     1081 cttaagcggt tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg
     1141 agaggcagtc gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga
     1201 attttcggta aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat
     1261 gagaggttca ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc
     1321 aactacgggc ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg
     1381 acaaatctcg gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt
     1441 tgtaggaaaa ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa
     1501 gcagagtggg cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac
     1561 caatggaggc tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact
     1621 caatcaagga aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg
     1681 ttcagctgat tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg
     1741 agcaactgta gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta
     1801 tttagtcatg gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt
     1861 gaatgtggac ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga
     1921 gaccaatggc ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc
     1981 ccattcagaa atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga
     2041 cccggattat ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt
     2101 cgtatcaagc cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa
     2161 aaattataat cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc
     2221 aacgaatgca gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa
     2281 gccaagagat gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac
     2341 gacgaaatca tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg
     2401 ggcaggatat aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc
     2461 caatgatgag agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag
     2521 aggtggccaa gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc
     2581 tgaacctgct aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac
     2641 aggtgaagca ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac
     2701 tattgatgat acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga
     2761 tgtattagaa attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa
     2821 caagccaagt accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta
     2881 tcatgatgcc ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt
     2941 tcttgcccct tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc
     3001 atttggccaa atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa
     3061 tccgtggatc ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat
     3121 gcaggatgtc ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact
     3181 ggaaattgtc agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa
     3241 taacggtcgg gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc
     3301 agcagagata acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat
     3361 tgatgaatcg aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc
     3421 tccttggatt catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag
     3481 attttgaatt accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg
     3541 agcctgggaa aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa
     3601 cagttgagac attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag
     3661 aatcaaaaag taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag
     3721 tgggagaaat aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc
     3781 cagaaaaaga gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga
     3841 acgtttctaa caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct
     3901 tgatttgaaa tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg
     3961 atcaaagcga tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata
     4021 tgttcggctt gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt
     4081 caataaaaaa agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat
     4141 tagaaggaaa aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag
     4201 aaaaacgctg gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga
     4261 atgaaaagga tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac
     4321 ttgttggagt cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga
     4381 aaaagaaatg aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg
     4441 tacacaaagt gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt
     4501 gaccaaacca gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa
     4561 tgatcctgat actcctttta cacctgacga accaaatcag ggaacatccg gattactgac
     4621 gattgaccaa gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt
     4681 atatgctgca ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt
     4741 cgtacaagta acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac
     4801 agaatttatt ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa
     4861 aaacgccgtg attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg
     4921 aactggcgct gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg
     4981 agcaaatgaa gggattggca catggattta ttcattagga gagaatgtgg aacaagggag
     5041 acaatcagtg gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac
     5101 attcacatgg tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga
     5161 tttcagggag tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca
     5221 gctcttattc atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt
     5281 tcaaagatct ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga
     5341 gcagaatcaa ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag
     5401 taagcatact tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct
     5461 tctgtagttg ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa
     5521 atttcccgag gatacaggac gagacttcca cctttttgat caataaagat tttatcgaca
     5581 tttacgatct gctgttcttt ccaattgatc tgttctagca cttgacgaat ttgttcagat
     5641 aaattcctgt cttttctgat atatccaatc ggaaggattt tccgattgat gatctctact
     5701 gcaaaattcg tataagcggt gaaaaaaaca atattactat gtgcattttt tttacgtatt
     5761 tgttcggcga catcaatacc tgtgagtgat tgcttcaagt cgatatcgat aaagaaaaca
     5821 tcgtgattat caatagtgcc caactggatc aactgattga tttgagagat agaagtgagc
     5881 tgcacgatat tctcgatatg atgattgacc aattctctga tgatccattc gctgtgaaac
     5941 tggttatctt ctatgataaa atactttttc atatgcaggc tcctattaaa aaaatatgtg
     6001 tacattttga aacaaaacaa tggaggaata agatggtcgc aacagtgaca ctttatttga
     6061 cctttacttt gattttagat ttaggtatct atttattctt ttcgaaacaa ctgctagtaa
     6121 aaaacagctt tggttgtata gctttgatgg tggtgacact tttacttcct atccctaaag
     6181 tgagctttcc ttacctagtt ggcttattat tgatgtttct tttttatttt actacgaaaa
     6241 acctgtttat cagctgtttg atcagtaatc ttttttttgc tatcactgga ctcagctttt
     6301 ttctggtttt tgatctgatg gattatttag gaaagagaca tcttggaaca gcaagttttt
     6361 ttgcactact tatcgcattt attttctatc tattagtaaa aagtatagac aaacagacga
     6421 gatttctcaa cttgcttttt acttatccaa ctgaacacta ttttggaggt atttgtattt
     6481 tattaagctg gggcgtgatt tacttggtat tgggaagtgt tcacttccgc tcatctaatt
     6541 atctgcttct atctcttttg tcgatagtca tcagtttttt ttctttgttt ttttccatta
     6601 tgttgatcag tttccaagta aaagaaagac aacatcagga atcgcttcaa ctgtatcaaa
     6661 taaatgaaga atattaccat catctagagg aattcaaaca tgattataaa agtctactgt
     6721 tttcattaaa aattactctt caggaaaata aaaaagaaac gttggaattt ttagaaatat
     6781 tagaagatca ttctgcagct atttttgaaa aaccgcaaat acaacagcta acaaatattg
     6841 tatccccagc tgtcaggggt gtctttttaa aatttctaga aaaagcagaa tcggagaaaa
     6901 tcccgatcca agtagttatt cctgtcgaag tgaaaacaat cccgattgat ctggttgttt
     6961 ttattcgctg tttatctatt tttatttcta acgcattcga tcatcgtgta gccgatcaga
     7021 gtccgattac gatcaatctg ctggaagaaa aagagggatc acgttttagt atagcgaaca
     7081 aggcaaatcc aacgaatttg acgctatcgg agatggtcaa aagaggaaaa acctctaaaa
     7141 aaaatggcgg gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac gaaaatgcag
     7201 aactaaaaat cgaattttca aaacagaatc actatttttt tgtagaaatg tatctggcat
     7261 ctagaaagag caaatcagcc tactgactta ctgtcaaagg ataagtttga ggaaagtcta
     7321 cacggagata gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg atgaccgttg
     7381 tcacccttct gtttcttttg ctatgtagtt aaacaaagta gttgacactt ccgctactta
     7441 gtattagtac gaaagtatac ttcatgatac taagtagata agaagtgaaa agcggaaccc
     7501 acgatcgtca aaatgctaac tgctttgctt acaccagata aagggaagag caatatcgct
     7561 tattttaggc gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg ctgacccagc
     7621 agttaagaga gttagaacaa gatgaaagta tccatcgaaa agcctataac caagtcccgc
     7681 ctaaagtaga gtactcgctc accgaagaag gaaaatcatt aagagagatt ctagtagcgt
     7741 tgtctgtttg ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa gaagacacgc
     7801 tactgcatac acatggtggc tacctaaatt attgattttc tatgacattt attttaaata
     7861 aaagaaaaca ggagtttttt taaaagcatc atctattttt tatgtaaaaa aatggtatga
     7921 ttaatcaagt aagaagtgat tggaagaagg caagcaaatg aatagtatgg aaaaagtcaa
     7981 ccagtttaga gatgaacgta attggcgaca atttcataac gaaaaagatt tggctatctc
     8041 tatttctttg gaagcatctg aattgttaga actttttcaa tggaaaacgc cggaagaagt
     8101 aaaagaaaca caattagaac gaatcaaaga agaactggca gatgtattga tctattcata
     8161 catgatggca gacaaccttc acctggatct agatgagatc attgaagaaa aattgatcaa
     8221 aaataatttg aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat acacagagtt
     8281 gtagaaatgt gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa atgagtctgg
     8341 agggagagaa aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat atcctcttgt
     8401 tcctcttgtt attagtagga ctagctttga ttttcaatga acagatcaag gattattttg
     8461 tcagagagac aggagataaa tatgctatag cgaatgtaac aaaagaagat ctgaaaaaga
     8521 ataacgataa agatgtcagt tttgactttg atgcggtaga accaatgacg acagaagggg
     8581 tcatgaggtc gcaaatgaga ggaacagatc taccagtgat tgctagtatc gcagtccctt
     8641 cagtttcaat caatttaccg gttttcaaag gcttggataa tacgtcacta ctttacggag
     8701 caggaacatt atctccagat caagaaatgg gaaaaggaaa ttatgcctta gcaagccatc
     8761 gtgcaacgaa ccctgaattg ctgtttacac cgctagaaaa tttagagatg ggtgccaaga
     8821 tctatttgac agatttagaa aatgtgtata catacaaaac attttttaaa gaaaaagttg
     8881 ctcctacaga tacccaatta ctgaatgaag tcgagggaaa agaaattgtc acactaatta
     8941 cttgtggcga catggacgcc gtcacgcgac tagttgtaca aggagaactg gaaagtgtta
     9001 catcgataaa agatgcgaca gatgatatga gatctgcttt caatctagag acaaaaacat
     9061 tttaggatac tgggacataa gtcgttacag attaaaaaca gccaaaggat atgaatcgat
     9121 aaggaaaaac caatttgctg aaaaaaagag aaacgcaaag aggtgcatct ctgatttggt
     9181 tgttttctag atagacttgt gttccagttt ttttattttt tatatgaaaa ggcttgcata
     9241 aataaaaatt cgatggtatg atgattttga ataagaaatg gattgttact gtacggcagg
     9301 caaaaccaga attcagctaa gaaacagtag gcgaattcta ggttttttta tttttcttga
     9361 gagggcgaag caaaatgaaa attgataaaa ttttgaataa caatgtcgtc atttcgaaaa
     9421 atggattcgg ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa aaaaagattg
     9481 gggacgagat ttcgccagaa gcggtccaaa aagaatttgt tttaagagat tcttttgcta
     9541 aaaaccaatt ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac
     9601 aagtagtcga actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga
     9661 cattgaccga tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta
     9721 atccattatt atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg
     9781 ctcttttgtt cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta
     9841 ttgcctttca ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg
     9901 ctaccacaat ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg
     9961 atgaagaatc tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt
    10021 atctcaaagg ggaaggatct gacgagcaag atgaatttct ctacgcatta gttcaaggaa
    10081 agtatccaaa agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa
    10141 aacaggaaat ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa
    10201 gtgagaaaaa aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt
    10261 gaaaaaatag gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta
    10321 aataaaaaag aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg
    10381 aagcggtagg aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat
    10441 tcagattaaa agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga
    10501 tccaagtcgt acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg
    10561 tttatcaatc gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt
    10621 ccaaaaatat tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag
    10681 gggcgatggc agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct
    10741 ggctgacagc tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta
    10801 ccttcttacc tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt
    10861 tagcagtagc aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg
    10921 gagaagctat cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt
    10981 ctgtcatacc aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa
    11041 aagtgattcc gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg
    11101 ttccattaac atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg
    11161 gtctcttcaa ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt
    11221 tatggcaagt attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga
    11281 atatcgaaca atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac
    11341 aaggtggggc tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag
    11401 ggatttcttc tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga
    11461 cattaccttt gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta
    11521 ttatcggatt ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc
    11581 cgactttcat taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta
    11641 caggaattgc ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa
    11701 cacaagacaa tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac
    11761 ggcatacctt aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc
    11821 aagttttttc ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac
    11881 tagttgcacc tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga
    11941 tcacaacgac tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa
    12001 atgggaatgg ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat
    12061 tgattcgttt tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg
    12121 tcattacgaa tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg
    12181 caaacgaaga tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt
    12241 tcagaaaaat ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga
    12301 tcgagacgga aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc
    12361 gattatcggc agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa
    12421 tcatcgagga atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat
    12481 gggattcaaa tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga
    12541 aggtactcct aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa
    12601 atatgatatt gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa
    12661 agaatacggt ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac
    12721 agtattagag agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc
    12781 ggcctttcac tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta
    12841 ccaaaatatt ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat
    12901 cggccacgaa ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta
    12961 cagcatcgat gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa
    13021 ttttttctgc acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca
    13081 taaaaaatat ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct
    13141 aaaagaatat ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga
    13201 gactgatcca caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt
    13261 tcttgaggca agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa
    13321 tgaattatac aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat
    13381 tgatcatatg gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg
    13441 tcatatcgaa gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc
    13501 ttggggatgt atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt
    13561 tatctatgtg gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc
    13621 ttttgattgg tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct
    13681 gaatgaaaaa gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc
    13741 tattctttta gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac
    13801 ttggaagtcg cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg
    13861 atgttgccga cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga
    13921 aaggcaatcg aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg
    13981 acggttctaa gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc
    14041 ttggagaact cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata
    14101 aagaaggaag atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta
    14161 tattatttga acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg
    14221 caattcagca gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga
    14281 tatactattg actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa
    14341 ggaattctga aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa
    14401 attggggaaa tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat
    14461 attgattatg aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa
    14521 taagaacagc caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc
    14581 agatacacgg ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt
    14641 cagaaggaat ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg
    14701 gcttgacgat cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag
    14761 aaatcgatac attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt
    14821 tccctatcgt attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag
    14881 taggtggcgg attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt
    14941 ttgcagtcgc tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt
    15001 ttgtcacagg aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca
    15061 tccaagaaga aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga
    15121 ggcagaatgg attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga
    15181 aagaatcaga gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg
    15241 tccagagcat cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg
    15301 tcgaaagggt ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact
    15361 attccaaaaa ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga
    15421 gatcagtaca cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg
    15481 gttatcactg aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct
    15541 atttatcgtt aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg
    15601 atcgtttagt tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca
    15661 cgagaacaaa atgatttttt cgttaataaa agaaacaagt atttgttgtt taaaataata
    15721 cacgttattg gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc
    15781 gatgaaaaca cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt
    15841 ctaaatacta tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt
    15901 cttttatttt aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt
    15961 tttatgaaac ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt
    16021 attgcgcaaa cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt
    16081 tcatactccg ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc
    16141 acaggtatct atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca
    16201 tttattccta cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct
    16261 gtcctcgttt tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg
    16321 atagcaatcg gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac
    16381 agcggcttgc aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg
    16441 ttggatcaag taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta
    16501 tctattaaaa atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag
    16561 gaccattttt ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg
    16621 aaaacaaaac agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac
    16681 tattcagcgc tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg
    16741 cagaatttgt tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt
    16801 acgaattagg tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg
    16861 tacctacgaa cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg
    16921 tacgtgaata tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga
    16981 agaggaaggg ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca
    17041 gtttgacgga tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag
    17101 ataacgaagt attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa
    17161 tcttcttttt gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg
    17221 tgctagaccg atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc
    17281 gggtaacgga tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt
    17341 tagatgatgt tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg
    17401 acacgatgct agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg
    17461 agacgttata tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt
    17521 ttgatgtatg tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag
    17581 aagatgcaaa aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc
    17641 ctgctggaaa atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaaaaat
    17701 aaaaaaccaa acgacgggaa agaaaa
//
LOCUS       DASHWW010000058        17244 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.058, whole genome shotgun sequence.
ACCESSION   DASHWW010000058 DASHWW010000000
VERSION     DASHWW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.058"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            7..1398
                     /locus_tag="U2R64_002121"
     CDS             7..1398
                     /locus_tag="U2R64_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEM8918916.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="U2R64_002122"
     CDS             1414..2454
                     /locus_tag="U2R64_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8918917.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="U2R64_002123"
     CDS             2473..3558
                     /locus_tag="U2R64_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEM8918918.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="U2R64_002124"
     CDS             3591..4553
                     /locus_tag="U2R64_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEM8918919.1"
                     /translation="MKMCYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="U2R64_002125"
     CDS             4546..5979
                     /locus_tag="U2R64_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEM8918920.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="U2R64_002126"
     CDS             5976..7046
                     /locus_tag="U2R64_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918921.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="U2R64_002127"
     CDS             7033..8454
                     /locus_tag="U2R64_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEM8918922.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="U2R64_002128"
     CDS             8467..9474
                     /locus_tag="U2R64_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8918923.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="U2R64_002129"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="U2R64_002129"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HEM8918924.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="U2R64_002130"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="U2R64_002130"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HEM8918925.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="U2R64_002131"
     CDS             11608..12285
                     /locus_tag="U2R64_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEM8918926.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="U2R64_002132"
     CDS             12275..13417
                     /locus_tag="U2R64_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEM8918927.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="U2R64_002133"
     CDS             13430..14407
                     /locus_tag="U2R64_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8918928.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="U2R64_002134"
     CDS             14407..15315
                     /locus_tag="U2R64_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEM8918929.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="U2R64_002135"
     CDS             15316..16068
                     /locus_tag="U2R64_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEM8918930.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="U2R64_002136"
     CDS             16073..17020
                     /locus_tag="U2R64_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HEM8918931.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6209 a         2206 c         3119 g         5710 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatgt
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gatagaaggg ctctttgtca aatgatgttg gtaaagagaa atcttagaat aatttggaca
    17161 gaacagaaag aagaaaacct ctttctgttc tgtttatttg gttaaaaatg ttttgccatg
    17221 acgaatcata attcgtagtt tgaa
//
LOCUS       DASHWW010000059        17113 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.059, whole genome shotgun sequence.
ACCESSION   DASHWW010000059 DASHWW010000000
VERSION     DASHWW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.059"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..189)
                     /locus_tag="U2R64_002137"
     CDS             complement(<1..189)
                     /locus_tag="U2R64_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918932.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGNI
                     LTLNLTTKTFVDAAEDYPF"
     gene            complement(326..661)
                     /locus_tag="U2R64_002138"
     CDS             complement(326..661)
                     /locus_tag="U2R64_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918933.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGNLVPYYTTWEMNEEGINNFPCKSI
                     KESISLTEC"
     gene            complement(682..2274)
                     /locus_tag="U2R64_002139"
     CDS             complement(682..2274)
                     /locus_tag="U2R64_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918934.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            complement(2293..2715)
                     /locus_tag="U2R64_002140"
     CDS             complement(2293..2715)
                     /locus_tag="U2R64_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918935.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDEIISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            complement(2717..3013)
                     /locus_tag="U2R64_002141"
     CDS             complement(2717..3013)
                     /locus_tag="U2R64_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918936.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            complement(3482..3712)
                     /locus_tag="U2R64_002142"
     CDS             complement(3482..3712)
                     /locus_tag="U2R64_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918937.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTAERK"
     gene            complement(3734..4540)
                     /locus_tag="U2R64_002143"
     CDS             complement(3734..4540)
                     /locus_tag="U2R64_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918938.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            complement(4551..5195)
                     /locus_tag="U2R64_002144"
     CDS             complement(4551..5195)
                     /locus_tag="U2R64_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918939.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQANIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDNHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVVDFSYFTR"
     gene            complement(5211..6413)
                     /locus_tag="U2R64_002145"
     CDS             complement(5211..6413)
                     /locus_tag="U2R64_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEM8918940.1"
                     /translation="MENDTNIVMEHLKRRAKRRLFLWLFGTSAGLITILITVFVTLFL
                     ILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVLYKL
                     LPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFP
                     NSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMSI
                     ITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGGE
                     FRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQ
                     EFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPL
                     PFLNSSKK"
     gene            complement(6487..6822)
                     /locus_tag="U2R64_002146"
     CDS             complement(6487..6822)
                     /locus_tag="U2R64_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8918941.1"
                     /translation="MKKNYHDLSQGDLVYIDLNPTKGHEQRGKRPCIILSKPNKYLNY
                     MIGVAPITTKAKPFPVHVDLNGTQKIKGQILLEHHRMIDIESRGFQFVEAVPKEILEE
                     CIEKIKLFY"
     gene            complement(6822..7085)
                     /locus_tag="U2R64_002147"
     CDS             complement(6822..7085)
                     /locus_tag="U2R64_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component,
                     AbrB family protein"
                     /protein_id="HEM8918942.1"
                     /translation="MLVKEIEMKKWGNSQGIRFGKEELSVLGETNTENLKFEMVVTEG
                     KIVLTPKNKKPETLDELFANYEGEPLGKEDKYEWGNMQGREII"
     gene            complement(7144..7521)
                     /locus_tag="U2R64_002148"
                     /pseudo
     CDS             complement(7144..7521)
                     /locus_tag="U2R64_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            complement(7652..9529)
                     /gene="ltrA"
                     /locus_tag="U2R64_002149"
     CDS             complement(7652..9529)
                     /gene="ltrA"
                     /locus_tag="U2R64_002149"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8918943.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            complement(10217..11911)
                     /locus_tag="U2R64_002150"
     CDS             complement(10217..11911)
                     /locus_tag="U2R64_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEM8918944.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLLKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            complement(12074..12667)
                     /locus_tag="U2R64_002151"
     CDS             complement(12074..12667)
                     /locus_tag="U2R64_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918945.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            complement(12668..13000)
                     /locus_tag="U2R64_002152"
     CDS             complement(12668..13000)
                     /locus_tag="U2R64_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918946.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            complement(13050..15422)
                     /locus_tag="U2R64_002153"
     CDS             complement(13050..15422)
                     /locus_tag="U2R64_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918947.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNVAKNVGSGAKNLASAGKSGLSNLNDIRKNGFGN
                     RKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEEKLDGTRAKELAEAVKNPSETLEKQKEKASEIKEGLKDAYGEGQVNA
                     AVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLPKTDPEQYRYKSNINS
                     ENEKRISDLPKRNQEVQTDDDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMKDSRLNQ
                     FKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLSESGETENASVQNIVTREAEP
                     KPIQNVHTGYKPANVAFTAPTKINVTRDTKNRNNALKEQLLRDIKQDIKP"
     gene            complement(15419..>17113)
                     /locus_tag="U2R64_002154"
     CDS             complement(15419..>17113)
                     /locus_tag="U2R64_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEM8918948.1"
                     /translation="AQKAVNALIFALLEQADQTGDYSKLTPNNLVELLSEIGGFNYQD
                     PDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNILSTAITGLNPFTLTKI
                     AKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKKFHEERVKVGYRGFCE
                     INFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIVYRKKRGETHLPELEK
                     EAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHIIVSIFLSQLYKELSTQ
                     CVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLWDLFIQSYQQLYAKYG
                     EQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENSTINSLGMNTHINRNVD
                     SDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHGETNLPYAYQYIEDFN
                     PSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMHDQIEEEAKENIFIKI
                     VQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIRKRLLLEAEKAVKE"
BASE COUNT         4580 a         3538 c         2640 g         6355 t
ORIGIN      
        1 aaatggataa tcttctgctg catcaacgaa cgtcttcgta gtcagattta acgttaaaat
       61 attgccactt tgataagctt ttgccgcttt gtctgtgacg acaaaagctc tgcccgtttg
      121 aatttctgtc acaaaaacga gattatctct gcttttttca acaacaactc caatcgttga
      181 atgaaccatt tcttcttcct cccttctctt tcttttgata taatgtagtc gcaaatcgca
      241 ccactcaatg aattggcgga aaacaattca ttgaaaaaaa gaatcctgga caatcacgtt
      301 caggactctt tttttcactt aataactaac actctgtgag tgaaatagac tcttttatgc
      361 ttttacatgg aaagttattg attccctctt cattcatttc ccaagtagta taataaggaa
      421 ctaaattccc ttcatattct tgaatgataa aatatttttc acccttcaca tgattacaac
      481 aatacacacc agtagctggg tactcaacga ctaaaaattg atttggatca aactgttcgt
      541 ttctcaacat ttctcttatc tggaacaaat gctctttttc taaacaatca ggaagttgtt
      601 cgattcgttc ttctcttaat gatccttcta taactttcca ttgatctaaa tattgtttca
      661 ttgctattcc tcctactgtc tttactgtct ttcttgttcc atttgaattc ttcgttgttg
      721 ctcttcgtat gctttacttg cgtggtattt ttcttcatgg gcattaatcg ttcgatttaa
      781 ttgacgcaaa ctccgctgcg tgacaactct ttgttggaat tgtttcctgc gcttcatgaa
      841 ttcttcgtaa ctatatttgt attcattcgt tggcaattgt ttaagcgttc gaaaggatcg
      901 ttcattgtaa atagattgca tctgatcaac actttctatt aatggtttta tttgactatc
      961 ctgtctcttc agctctgtta ggatggcatt tcctgtgcgc ttttttaaat caaagagagc
     1021 atttttctct gcatcctttg attctctctt gctttcccca taaagacttt ttgcttcttc
     1081 tttcaatgct tttgaaatct gtatatattc ttgatattca ggttcttttg ttaaaacata
     1141 tttggttaac tcatcgagtt tctctcttgt gtatggtgaa agtttggttc gtttttcatc
     1201 cccgtaattc cattccgaac gtttgtcagg tagggtttta tatacttcat ttaataagtt
     1261 catcgcgtgt cgatcgtaac gcgctggctc ttttaccact tttgttaagg tgttacgcaa
     1321 atcacttttc cgcgtcaata aatttcgttt ctccatacca atcattcgat ccttttcata
     1381 agaaaaacgt tctaactcat gtacataatt ggtcttcatt gcgtctaatg ttgcttgtct
     1441 tctcttacct ttcggtacga tataactcac accattttca acctccgtgt aaggtttacg
     1501 cgtattttct ttttcaacaa ctgcaaaatg aatatggata tgtttagtgt tacggtgaat
     1561 cgttgccatc cagtagcctg tttcgttcag ttgctctttc tcgaataatg tctccatcat
     1621 ttttcttcca gctgctttta acccttcttc atctaaagta tctgttttgg gatcgtacaa
     1681 tcctattttt tcaagatacg aattatcatg agaaacaaca tcttgataaa tgattgagcc
     1741 tttttgttgt cctctttgga agatttgctt aatctccttc agatcacttc ctttcacttc
     1801 gtctgaagct atagaaaaaa ctccaggaag atttcctgaa gcttttttat ggggttctgt
     1861 ttgatatttt ttcattgctt ggttcaagcg ttggtattct ttttgttcac tttgcgtcag
     1921 ttctttcttt tgttctaacg catagtgacg tgtcatataa gaaagataat tggtaaaatc
     1981 ttgttcctct aacttgtcaa aattgattcc atgttccatc aacgattgag cttcattcga
     2041 cgtttcactg aattctttac ccgtcttact ctccgaaaaa gtttctcctt caggaatata
     2101 aaactcctct aaagcattct tgattcgttg aagttcctgt tcttcttcgg gcgtacgtcg
     2161 ttccttttct tcaagagcct gttcccttgt aatatagtca atataagtag aaaatgactt
     2221 tttattcggc aaagtaaatt gacaagtgag aataactgaa ggcgattgag tcattattat
     2281 cctccttcat ttttatcttt ttagaatctt cgttggatca aatggatcta ctctggcatg
     2341 aacagattca ttcacaggtt tcttcaactg aggggaatat ttttttgttt gattggattt
     2401 aatttttcct tccactcgtt cttttgcttc ttgataaaca gttgaatttt taccaattaa
     2461 tattcctgta tctttcaaat gaagatccgc aaattctgaa accatttcgg ttaaaataga
     2521 aatttcttta ctcattccat tcaactttgc ttgattggaa tttacttttt tctccacttc
     2581 tggatcatag ttcatacata aaaagcgaac agcttcacta tagtttttaa cctctgcatg
     2641 agtagaaata atttcatcca atacatcgat atgtgtttgg tgaaagtaaa tgtgtttgtc
     2701 tataaccttt gccatatcaa agttcacttc ctctattttg ctcaatcaag atttctataa
     2761 tacgattatt ttggctaaca tattcttcta atatctttgt gttataactt tgaatttctg
     2821 aaaacttttc taataactgg tcaaactttt cttgtttgta ttccatcaaa ggacgatcaa
     2881 aatcattttc aacgagtagc tttaaataat cattacgact ccatttattt cctgtacgat
     2941 tacttagttc aacgcatctt cgatcaattt cagaaatgaa ttttggatct aaatctctaa
     3001 ttttaacatt cataaatatc ctccaatata atataggata gtgaaaagga tcctatcctt
     3061 ttcgctatcc tacctctatc cttttactat cctttgctat ccttgtacta tcctatatat
     3121 tggtattttg gggtcattta tttttttcag aaacgtgata ggcacagcct atccaaccac
     3181 ttttttttaa aagtggggtc acgtttcctt atgctcttta aaaattaagg ttatttgtgt
     3241 atttagacaa taaaaaatcc ttctaacttt gtcgattaga aggaaatatt ttgtcatatg
     3301 aaaaatgaat ttaagaaaaa gtgtatgcta taattgatac gctgtcttcc tgtttggttg
     3361 aaatcttcag ccagaaagga ggagtgttaa atgttttatg tgcttgatgt ttgtgttacg
     3421 gtgatatagc tgatccataa acatttttga tatacttttt tcacataaaa tcctcctgtt
     3481 tttatttcct ttcagccgta aaatattttt tagcagctac atatagagct tcaaacgatc
     3541 tgaattttaa agtatctaaa ttctttcgac cattcttcaa ctcagatatt gttgtgttag
     3601 ataaattcac ttctcgacat atttctttag cttttacaac tttgagatag gctttaatca
     3661 atactttttg ctcagcgaaa gtatctttgt cagccaagtt tgttcgcttc attttttcac
     3721 tccacctgtc cttctaaatc ttttcttttg tcatacgatc aattttttct tgaagttttt
     3781 gaatgatctc ttcttgatct ttcagttgcg ttttcgatgt ttcaatttct tgctggtagc
     3841 tattaatctt gttttcagta ttttcctgat catctgcgac ttgataaggc aattgatctt
     3901 ttagcttctt cactaattct tcattcaaat caatggttgc ttggaaagat tccatttgtt
     3961 tttgagctgc tttttgttct ttcttgtatc ctttcacttt gtaattgatc gcgtgttgtt
     4021 cataatcttc atctttcact tgatctttaa ccttatcttc gtgcacgtaa taaatcagat
     4081 cttgtggttc ttgcatatcc acttttggat caattttttc aggaataatg gttaaacgca
     4141 tggcgatata ttcttctggt acatgcgtta gcttcactgc aaaataatca tcagacacct
     4201 tgatcacttt ggctcgtatt gcttgataat cccctttagc tgtctttact tctacgcgat
     4261 aattaagatt agccagttct tttaacaagc tttgatcttc atcgtcgatc gcaaattcaa
     4321 aaactaattg ctggttcgct cctttttctt ttgaaaccat tgtcagctct ttcgtgttta
     4381 aaaaggcgtt cgtgcttacc tcatctggta tatctacctt ctgattcgta taaatcggac
     4441 tagcaagaat caaaaagccg agaatcataa agattcccag ccattgaaga taactttttc
     4501 gttttttgaa acgttgtctt tctccttttt tcttactcat tttcttcctc ctaacgagtg
     4561 aaataactaa agtctacgac tttccattga ccatctactt gtttttcagt gacagttaat
     4621 ccacctttta ttttttgtgg tttgacatct ttgaattgcg gattgccgat tgtataatca
     4681 acaaatacga caaaattttg ttcctctttt acactgcttg tttgagcgta agtttgcacg
     4741 tcacctaatg taaaggagta acttccgtaa tcatcatgtt ggtgattatc gtctgcagga
     4801 cttaatttgt cgatcacttc ttgggttgcg acatctttta gtttttccgt taattcattt
     4861 ctgcttaatg atttatcaat ggccaattga ccgaactctt ctgccgtctt tctttgtgct
     4921 tcagttactt cctcttttgc ttttgtgcca tcttgttgct tcagctgatc gatttcttgg
     4981 tttttctcat tgatggtttg atttaacttg tcgatgttcg cctgtgcctc agaggaattt
     5041 tttttgagct tctcagacgc gtttttagcc acttcttcaa ttttataggt atttgctgct
     5101 tgttcctctt tcagctgcca aaacaacgca atattgccga ttaaactaac gctaattgca
     5161 gctgttaaga cgatttttaa cgttttattt tccatatttt ttctcctgat ctatttttta
     5221 ctgctattca aaaatggtaa cggatcgatc catgtaccat catcaatgaa tgcatgtcct
     5281 tgtgcttgac gccaatccat tcgagtaaat cctaaatgca agtgtgctgt atctcgtatc
     5341 ccaattactt gaccaacttt cacttgatcg cctactttca ctcgagaatt tcctgtacta
     5401 tttgcaaatt cttgatacac catattcaag ccatcgtaat taatcacgat cacacacgcg
     5461 cccaaacctg aaataccagg attgccaacg tacacgactt ttccgccatg aaccgcatga
     5521 atctcacttc ctggatgatc aactgaacca aaatctaatc catcatggaa gccgttcgga
     5581 cggaattcac cgcctggatt cgttccaaat aattgaccac cgctgaagga acttttatct
     5641 aaactgctgc cagggaatgg attcgtccat tcaccagtaa ttgtgccatt gttattgcca
     5701 ccttcacccc aatgtttgat ggcgaattca tcatattcgg ttaatttatt agaagtgata
     5761 attgacatac aacctgtata atacggacta tcttcagtaa ttcctgcagc ggcataacca
     5821 cctcgtccta agatcaataa gcttgcgcca gggcttttat ttcctacaca tgcattaaaa
     5881 tttgattgtg tggctaccat aaagccgtaa taggagaatg cagcttttga gttgggaaac
     5941 ttcatgtacc agcccccttc aatgccacca attcctcgtg cagttccttt aggaaacaga
     6001 caaccatcaa accaagtaat cccaaaatag ttgagatcat ttcttgcgga cgccgacgta
     6061 ccaaacgctg attcataacc gtattgcgaa agaatcacac ttggtaataa tttatataac
     6121 actgctgcac ctacggcata ttgcgcaatc tcatcagaaa aagggcctct tcctttgatt
     6181 tctttataaa tcggtaagcc ttccgaatac tctcctgtaa aagcttcgcc accactactt
     6241 gaatcggaat ccgaattatc aatcgaaccc gccgcaagta ttagaaaaag ggttacgaac
     6301 acagtgatca aaatagtaat caaacctgca gaagtaccaa acaaccacaa aaataagcgt
     6361 cgctttgcac gacgcttcaa atgttccata actatatttg tatcattttc catatagtca
     6421 gtactcctaa ctttttaatt ttaaacaaca aaaaagcgaa gaaataataa ttattcttcg
     6481 ctgcttttaa taaaataatt taattttttc aatacattct tctaaaattt cctttggcac
     6541 agcttccaca aactgaaaac ctctactctc aatgtcaatc attcgatggt gttccaaaag
     6601 aatttgtcct tttatttttt gcgtaccatt caaatcaaca tgtacaggaa aaggcttcgc
     6661 ttttgttgtt atcggtgcga caccaatcat atagttcaaa tatttattag gtttagataa
     6721 aataatacat ggtcgttttc cccgttgttc atgtcctttg gtaggattta aatcaatata
     6781 aacaagatct ccttgcgata aatcatgata gttctttttc attaaatgat ctccctacct
     6841 tgcatatttc cccattcata tttgtcttct tttcctaagg gttctccttc ataattggcg
     6901 aacaattcat ctaaagtttc tggcttttta tttttaggag ttaaaacaat ttttccttct
     6961 gttaccacca tttcgaattt taaattttca gtattagttt ctcctagaac tgacaattct
     7021 tcttttccaa aacgaatacc ttgtgaattt ccccattttt tcatttcgat ttcttttact
     7081 aacatggaat ccctccttct ctcacacatt agtatatact tgtatacacc aaaatacaag
     7141 aagttacttt ccaccatcaa acaatttcaa ttgacgtttg ttcggactaa aatgaacacg
     7201 aatggtttct tttgagccaa aattgatcac agcgtctcct tgattttgtt gaggaatgga
     7261 ttctagttct gagttcgtca ttgatttacc aactaatcct tctatatgac gtaaaataga
     7321 ttcatccata cgcataaaga tcttcgtaga agaaaattca aagactttct tcagtttcga
     7381 gaagttatca gaagacatat tttctggcac catttcttgt ggggattgtg tagctaaaac
     7441 agtcattgct tctactttac gcatttctcg ttgaaagttt gtgacataat ttaccgtttc
     7501 aataaaatct ggattaatcg atactgatag gtaagagttt gatattatct ccgtcttttc
     7561 ccccagtcca caccgtacgt gcgactttca ccgcatacgg cgttccctcg tctataaaag
     7621 acattctgtt ttcccgtcct acaaatattt attaagatat ttcttcgtta ccaactttta
     7681 atctcaactc attgagtttt tctttttgtt ttggatttaa ttttagatat tttagaagtt
     7741 cctcaatcgt ttcactttgt gtagcgtgta ttacccgatg aacctcctca gtaacaatca
     7801 ctaggttttc atagctatca cttttgcttt catgataagg gataatatga tgacaatgca
     7861 tttcagataa gataagctcc tcacctgtta ctgcacatct tcccttttga gcgatgaatt
     7921 ttgaaattcg attgtccgca aattcaatcg ttgctctctt actaagcact ggattgctac
     7981 acaaccacga tatcttccat tcttctacgg tttgttgctt cttatgaatg gcttccctac
     8041 cttcttcggt gtatttatta atatttcttt ttttacacat cggatgtctg tgttgaatat
     8101 accctactgg taatattgga aaccctctta tatatcgtat ttgtcctgac cgtaggtaag
     8161 gcttgtatcc ttcgtacttt ccgtattgtc cttcttttga gattccttgt tctcgtagtc
     8221 gtatttcaaa acttggtctg agttctcttg caatttttcg cattgctaca ctacaatgag
     8281 tcgcaatttt gaagtaatta tgaatcccaa taaccatact gttatagact ccaatataga
     8341 taaaggtatc tttgctatta ggactttttt gaattcgttt gatttgtttt tttagtttca
     8401 ctttaatcat gctttgtgct tttgtaccta tatgcgtatt aacaaccttt ttgttacctt
     8461 tggtcactaa tttcatcgta aagcctaaaa attcactttc ttcttttgaa agatttgtga
     8521 tttttgactt ttcttcagat attggtaact ttagacgctc ctgtaaccac attttagttg
     8581 catagaaaac ttttttcgct tcattataat ttctacagaa aattttaaaa tcatctgcgt
     8641 atctcactag gtatatttct tttagagttg tactctttct gagcttgtga tagatattac
     8701 ctttatccca agctccattt ttcctaaaat gatgttttag ctctttggca tctttttcct
     8761 cccactgatt tgctatccac cagtcaaatt cgttgagatt gatgttcgca agtaatgggc
     8821 taagtattcc gccttgtggt gttccttttg ttgggtatat caacttccca tttggaagta
     8881 ctacgggtgc tcttaacatt ttcctaatga ttaagagaag ctgtttgtct cgtataccca
     8941 tagaccagat ttgtctcatg agtttagtat gattgacttc gtcgaagaaa cctttgatat
     9001 ctacatctac cacatattcc atgtgacttt gattcattcg ggccatacaa tctgctattg
     9061 cgtgttctgc tgatctattt gggcggaaac catagctgtg attattgaat tttgcttcac
     9121 atattggttc taatacttgt aagatgcatt gctgcgcgat tctatcccat attgatggaa
     9181 tacccaacgg tcttaattta ccattatatt taggaatttc tacacgcctt actttccgag
     9241 ggttataatg tgcgaatcgc ttcctaacaa tttctacgaa ttcattacgg ttgagatttt
     9301 caatatcttt aatcgttact ccatcttctc ctcttgtcac actaccgtga tttctcttga
     9361 tattacgata tgctaggaca atgttgttat cagaaatgat aatctgcatt agattcttga
     9421 aattatctcc cttcaaactt ttggagtata tcttatcgaa gatttccgtc atgccataat
     9481 attctgcatg ccgcaacttc ctatcttttg gacttgtttc ttttgtcatg gtttatcacg
     9541 ctccaattgg ctcgtgacct ttttagtcat acgagaatcc catggttgaa cgggtttcat
     9601 gacttttaca gacgaatcga gcctgttcct ccagttccat tacagaacct tcatcagtcg
     9661 tgactctact ttcaccatca ctaaagtaag ttatttgtca ttcacatatt tcttactacc
     9721 acttcatcga gtatgcactc tccatgttga tggcttcccc tgttccctta tatctatcca
     9781 catgccttaa cttagatgct agcttttgcc ccctaacttc tcctacgcct gtaacgcagc
     9841 atggtctttc ataacaacga cttttactca accacaagtt agcacaatga gtgatttttt
     9901 gctcactgtc tctcccattt ctaggagcta tgcctttcgg acagtacatt cgctagttcg
     9961 tcagtacgtt tgtacatact caccatatta agtttttttg gacacccgac ttatcggata
    10021 caccctttac ctctaaagaa ctttcgtggt attcactatt tcttttacct tacggtatcc
    10081 ttcagccgac ttcaccgagc ttcacacaac gttggtctgc ataaactact tgttgcatgt
    10141 cggagtatca gtggaagccc tttgtggcgt tacccactca tttgacttct cgttataaga
    10201 gttattacaa tagtttttag actacttgca acccacagct tttcactgca gaacaggtcg
    10261 caccattatg gcactcatca atcatcgcca agaagcgttt gaagtcttgt tcttccattt
    10321 gtttttcttt aagtaaacgt cgttgtcttc ttccttgaat caatgcctga ttccaaatca
    10381 acgtcatagc catgtacatt tgacattgtt gtacccctcg atctaagcct gtaatagagt
    10441 caatgtcaaa aaagaccaac tgttgttggt caaggtgtcg aatcgtactg tgaccatcaa
    10501 aaatcatgcc atacgtctca cataaggatt ctacgatgga ttccatttct tcttttcgat
    10561 tctttttctc ttgggaagca cctggtaatt ccagttgtcc taaaaagtct aaaaattctt
    10621 tgaacgtcgg ataagcttct ggatctttcc ctgtgacttg cgtctcagta tttgaacgcg
    10681 aatttgagga agtaaagccg cgtggtactg ttccatactc ttcataaaaa cgatttaagt
    10741 aggtcttaaa ttctgctttc atcgttcctt ttagctgagg actcactaac tgtacctgat
    10801 agactacttt gtctaagtgt gtttgatagg acgctgcttc attgatcttc aaatctttga
    10861 ctgatccatc gtcatataaa ctggatgctt catcatacgt ccgtgtggca aatatttcta
    10921 aaggattgat catcccgtca gacccgtcta agcgcaccat aatgccgtta tattccttta
    10981 agaatgggat aaagtctttc cccttttcaa agccccaaat aaagtctcct gcagctaaat
    11041 gggcttccgc gatcatttta agaacggttg atttaccagc tcccatcatt cctagaagca
    11101 aggtattagt agacaaccgc acactatttt tatatgtcgc attccagaca aatgggccac
    11161 ctgtcatggt ttccccatat tgagtccctc ctggatcttt tagcgtttgg tggtggaacg
    11221 ggaatcctcc gccaatattt aacgatggta gtgattgccc tttgatattt ccaaaccatt
    11281 cagcttgttc atcgaacatg gtaaacatcg attgccaatc tcttttcgtt ttgtgcagat
    11341 aggtcactgc acgataatcc atccctttta aattttcaat cagttcctgc gctcgttcat
    11401 ctacttcttg aatcgtgttt ccgtaaacat gtactctcac tttgacttgc ttagaaattt
    11461 ccccattaga agtcaattta cgagcatatt ccgctagttc caggtattct tctgcgcttt
    11521 tatttcggtc agtcgctttt cgttcattat ctgatcgatc atttaattca tctaaggcac
    11581 gattgatttg atcaatcact ttttgctttt catctgtgct aacatcgagt gtggccactg
    11641 tatgaggatt gttcatgaga ttggccaacc aaaaaagcgt aggatttttt gtgtagtgat
    11701 aaactgtcac acatcgtgaa taaccattac catacgtcac atattcttca tcaaaattta
    11761 acccaccttg tggcatcact tgttttaaaa aatctaaatc ataccctttg gatttcaaaa
    11821 tttctatttc ccgatttcct agttgcttta atggatcaag tactttttga tcattttgtg
    11881 gtgaaaaagc tgttttaatt gcttctaaca tgtacagtca cctcttcttg tttgattctt
    11941 tacttggtta aaagattgcc cttttcccaa cttacccagg cttaaagtgt gaggaaattt
    12001 tctagtggtc tcttccttcg gaacatcttt ttctaaccat atcaatggat atttcattct
    12061 ctcttctcca ttcctactca tcattcatat tgttcattcg atacagaatc ttgatcaatt
    12121 cttttttgta gagtggtttt aaccctaaaa tgccactaga tcgcattaac tgacggtttc
    12181 tggtttgtaa atccttgatt gtctttcctt caatgacgaa aaagaagctt aagtcaggac
    12241 gttcttgttc tgctcgtttc aattcctgga tttcttcgac taatttcttt tcatattttt
    12301 ttaatcgttg tagatttctt cctaaggatt gttccatacg attcttatct aataactgcc
    12361 gcttttgcac gatttgttcc gttagatccg tctctgtagt caaactaact aacttaattg
    12421 ttggcacata cgtacgcatg acggtggtca actgattcat tcgttccagt ttctcttgtt
    12481 catttaatcc ctccacgtca gtggaaacga cacgataata acgttgaaaa tgatcttctt
    12541 tagtaactaa gactccctct tctgtacagg atttataagg aaataaatcc aagatagatc
    12601 gttcttctgg ttttccaaac tgcaaaatag atttcttatc aactgaattt tgtcctttga
    12661 ctcgcattta ttcatcctcc ttatacgtac catgataatt tcggttagga tctaacgcat
    12721 gataatggtt cttgtccgca aaaaaaatag actcgataat cgcaaaaatt tgtcgttgac
    12781 ctgggttatt atagggtcgc caaacaatca ctaacgctat cgcaatccat aagccataat
    12841 tcaagagtgc aaaaaagagt ggtaagtgga caagattatt gaccattttc gcccaaaaaa
    12901 agcagccacc aagcgttaat agatctaaaa agaaaaaagc gaaaaacttc cattctccac
    12961 taaatcttgg agggtttttc atgtttatat atttatccat aattgatttc tccttttcat
    13021 ataaagaaaa ggcctaactt gtaggccttt tatggtttga tatcctgttt gatatccctc
    13081 aatagttgtt ctttcaatgc attgttcctg tttttggtat ctcttgtcac atttattttt
    13141 gtcggtgcag taaatgccac atttgctggc ttgtaacctg tatgaacgtt ttgaataggt
    13201 tttggttcag cttctcttgt cacaatattt tgaacggacg cattctctgt ctcaccactt
    13261 tcagataaat tgtaagaaac agttgtcaaa ttcccatttt caggcaaacg acttgatttc
    13321 atttgaacag tacctgcagg tgattgatga acaaagcttt gatcattctc tttgaattga
    13381 ttcaaacgac tatctttcat tggtaaattt tgtgtcttag gcaaaccaat tttcgttgat
    13441 ttttcagttc caacttcgat gccattatca tttggcagat cgatggaatc atcatccgtt
    13501 tgtacttctt gatttcgttt tggtaaatct gaaatgcgct tttcattttc agaattaatg
    13561 ttagatttat aacgatattg ttctggatct gtttttggta attgaccatt ttgtccttct
    13621 tctgaatttt cgttagaatg caactcatct tggtgatctt tggctgaagg aatcgctgca
    13681 ccttcttgat tttctttttc ggttgttgta ttagctttta ctgctgcatt gacttgtcct
    13741 tcaccatacg catcttttag tccttctttg atttctgaag ctttttcttt ttgtttttct
    13801 agtgtttcgg atggattctt cacagcttca gccaattctt tagctctcgt gccgtctaat
    13861 ttctcttcta aggtgtcttt ggctttttct gtaagatctt cagctgttcc ttttaaccca
    13921 cgttcattga cgtaaccaag accttctgcg gctttagaaa caccattttt cgctttcccg
    13981 aacatttcgg aaactgtttt cttactatta ggtacagttg tagctttatc gtctgattgt
    14041 tcttccccgt tatcaggggt aacatctttt cgattaccaa atccattttt acgaatatca
    14101 tttaaattgc ttaaaccact cttaccagca cttgcaaggt ttttagcccc gctacccaca
    14161 tttttcgcaa catttcctaa ggcaaacatg ctaagaagag aattgctgcc gtttttcaga
    14221 ctcgtatcaa cgccgaaaat tttcgtaact gattgagagc ctttgaatag cgcaatggtt
    14281 aatacaatta aagcgacaac atacaagaat ccattgatct ttcctgccgc atgcaaatca
    14341 ccgatacctg aaagcattaa tgtatagatt cgtaattcta aaatcgtaaa tgccaataac
    14401 aagaaggatt gagaaatatc ttctatagca cttttcatcc gttgtcctgt ctcaaagtcc
    14461 gttgacgcgg caatcactaa atagaatttt ttaaatacca gctcaataat gcaagtaaca
    14521 atcgtaaaca agataaataa ataggctacc gacaaagaag attcaccagc taaaataata
    14581 cctggactac taatgtatcg gcgatagcct gaagtataca catattttgc taaaccttca
    14641 tcactaattt gaacagggat ttctttccca ttatcgtcta actctagtcg atactgtaat
    14701 gcctttaacc gatctttttg tactgtacta atatcacttg attcagacat tttcttagct
    14761 tgatcaggtg taataatccc attgatattc gctgttttaa aatttttcgc cgtgagagca
    14821 tttcttttgt ctgttggtat gtgttctact ttgttcggat cattttctag taacgtactc
    14881 acatcaatca cattattttg aataatttga aaagcaggtg aaccagtttt atctgcttta
    14941 tttgctgcag tcacgtctcc gtaaaagttt ttactaatat ttagcccttc atcgattaaa
    15001 gaactaccac caaaaatcaa aatcatggcc ataaatagat taaccaagat atttttgatt
    15061 tttggtggat gtttactcat aaaaaatttt aagcctaaat aaattaatgt gacgacacaa
    15121 aaaagagcca ataccttact aatcaaactt tgaaacagtt cattaacacc agcggcgttc
    15181 aataagtctt ttaaatcaaa gctttgataa attgtttttt ctagtaaagt attgagatta
    15241 tataaccctt taatcaaacc ccataaaaaa gtattacaaa tccaactgaa tacatcttga
    15301 tactgcagat aattaccata atcttgtaag actttcgtta cggttttggg atctgcatcc
    15361 ccatccccaa ataagcctga ccaccagtcg gcaatgccgg aaaatattcc tccaatgatc
    15421 attctttcac cgccttttca gcttctagca aaagtcgttt ccttataacc tctgtaattt
    15481 cttcattttg acgcaatttt tcaaggtatt cttgcaaacg atctatttgc ttctcttcat
    15541 aaaattgaat aagtaacttt tgtgccgttg agttgtctaa agattgaacg attttaataa
    15601 aaatgttttc tttagcttcc tcttctattt gatcgtgcat attgtgataa agtcgacgtg
    15661 catagatatc aggtagaaaa taatcgtaat caatttgtaa agccttaaga tccaagtccg
    15721 catgtgtaca atgtatgtct atatcattga tatcccacga tggattgaaa tcttcaatat
    15781 attgataagc ataaggaaga ttcgtttccc catgattaaa aataggatac ggccgtattt
    15841 tatgaccttt caaatcttgt cgttttaaag gagcgagtac aatcgtttca ccttctaaaa
    15901 aagtagaaat tctttcagga gttaagatgc gatctgaatc aacattgcga ttgatatgag
    15961 tattcatacc taatgaattg atggtactgt tctcttgttc aaccgtctta ttccccactt
    16021 ttttggaaaa ttcttctatg gtattatcgt ctgtcgacat aatataaata tgtgtctgac
    16081 aattttcttt gataatcgct gcgttttgtt ccccatactt cgcataaagt tgctgatagg
    16141 attggataaa caaatcccac aacatgtttc taccagctgt gactgtcatg attccttcca
    16201 tattatccat tggtggcata ttcccaaatt catctaaaat aaaatgaatc ctacggtgac
    16261 atttatctcc tttagtctta acacattgcg tagataattc tttatacaac tgactaagaa
    16321 aaatactaac aatgatatgg ttagatggat cataatcagg tgtgagcata aaaatagcca
    16381 ttggtttatc ggtatagtgc atccgaatag actctactaa taagttactt ttatcctcat
    16441 ctaatgttag aacggcttct ttttctaatt ctggcaaatg ggtttctcct cgtttttttc
    16501 gataaacgat atttccctct tcgtctttca atactctttg agaaaactca taccaagcaa
    16561 catattcttt tcctcgatga tcgtatttta agcaaacatg atctccctgt tctaaatgac
    16621 aatcaaagtt aatttcacaa aaacctctat agcctacttt gacacgttcc tcatgaaatt
    16681 tttttccttg atgataaaac tctacaacaa ttcgctggtt taacagactc tcgtgtagtt
    16741 tgagatccaa atacttcgga aaaccaatgg acttataatc aatggttgat tgagaagtca
    16801 ttttcgcaat tttcgtcagt gtaaatggat ttagtcctgt gatcgctgtc gatagaatgt
    16861 tgcctttcgc tttatcagaa ccaatttttg ttgccccata ttgttttttt gctatgtttc
    16921 caggtggtaa ctgattcata aattcatcta aagcattgag ctgcttgaat tcattatcag
    16981 gatcttggta attaaaacca ccaatctcag aaagaagttc gacgagatta ttcggtgtta
    17041 atttggagta atcccctgtc tgatccgctt gttccaataa cgcaaaaata agcgcattga
    17101 cagctttttg cgc
//
LOCUS       DASHWW010000060        17006 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.060, whole genome shotgun sequence.
ACCESSION   DASHWW010000060 DASHWW010000000
VERSION     DASHWW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.060"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..125)
                     /locus_tag="U2R64_002155"
     CDS             complement(<1..125)
                     /locus_tag="U2R64_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HEM8918949.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="U2R64_002156"
     CDS             complement(229..540)
                     /locus_tag="U2R64_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8918950.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="U2R64_002157"
     CDS             complement(542..739)
                     /locus_tag="U2R64_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HEM8918951.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="U2R64_002158"
     CDS             complement(1133..2860)
                     /locus_tag="U2R64_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEM8918952.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="U2R64_002159"
     CDS             complement(2853..4046)
                     /locus_tag="U2R64_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8918953.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="U2R64_002160"
     CDS             complement(4233..4877)
                     /locus_tag="U2R64_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8918954.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="U2R64_002161"
     CDS             complement(4971..5105)
                     /locus_tag="U2R64_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HEM8918955.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="U2R64_002162"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="U2R64_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HEM8918956.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="U2R64_002163"
     CDS             complement(7236..7709)
                     /locus_tag="U2R64_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HEM8918957.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="U2R64_002164"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="U2R64_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEM8918958.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="U2R64_002165"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="U2R64_002165"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEM8918959.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="U2R64_002166"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="U2R64_002166"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEM8918960.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="U2R64_002167"
     CDS             complement(11756..12895)
                     /locus_tag="U2R64_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8918961.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="U2R64_002168"
     CDS             complement(13204..13917)
                     /locus_tag="U2R64_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEM8918962.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="U2R64_002169"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="U2R64_002169"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEM8918963.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="U2R64_002170"
     CDS             15106..16638
                     /locus_tag="U2R64_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8918964.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="U2R64_002171"
     CDS             complement(16829..>17006)
                     /locus_tag="U2R64_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8918965.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3494 c         2910 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga aaaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DASHWW010000061        16731 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.061, whole genome shotgun sequence.
ACCESSION   DASHWW010000061 DASHWW010000000
VERSION     DASHWW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.061"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1412
                     /locus_tag="U2R64_002172"
     CDS             <1..1412
                     /locus_tag="U2R64_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8918966.1"
                     /translation="PTVEGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTN
                     TPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNV
                     TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNA
                     DKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTY
                     PDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYT
                     WKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTG
                     KTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNV
                     VVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGL
                     ILLGTLGLLGYKNRKKENE"
     gene            1546..2889
                     /locus_tag="U2R64_002173"
     CDS             1546..2889
                     /locus_tag="U2R64_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8918967.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            3001..4452
                     /locus_tag="U2R64_002174"
     CDS             3001..4452
                     /locus_tag="U2R64_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEM8918968.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4801..5433
                     /locus_tag="U2R64_002175"
     CDS             4801..5433
                     /locus_tag="U2R64_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HEM8918969.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            6021..7460
                     /locus_tag="U2R64_002176"
     CDS             6021..7460
                     /locus_tag="U2R64_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8918970.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7755..7973
                     /locus_tag="U2R64_002177"
                     /pseudo
     CDS             7755..7973
                     /locus_tag="U2R64_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8222..8437
                     /locus_tag="U2R64_002178"
     CDS             8222..8437
                     /locus_tag="U2R64_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918971.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8654..8910)
                     /locus_tag="U2R64_002179"
                     /pseudo
     CDS             complement(8654..8910)
                     /locus_tag="U2R64_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9097..10008)
                     /locus_tag="U2R64_002180"
     CDS             complement(9097..10008)
                     /locus_tag="U2R64_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8918972.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(10027..11031)
                     /locus_tag="U2R64_002181"
     CDS             complement(10027..11031)
                     /locus_tag="U2R64_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEM8918973.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(11028..13151)
                     /locus_tag="U2R64_002182"
     CDS             complement(11028..13151)
                     /locus_tag="U2R64_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8918974.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(13156..15603)
                     /locus_tag="U2R64_002183"
     CDS             complement(13156..15603)
                     /locus_tag="U2R64_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8918975.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(15590..15979)
                     /locus_tag="U2R64_002184"
     CDS             complement(15590..15979)
                     /locus_tag="U2R64_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8918976.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(16039..16542)
                     /locus_tag="U2R64_002185"
     CDS             complement(16039..16542)
                     /locus_tag="U2R64_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEM8918977.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(16555..16716)
                     /locus_tag="U2R64_002186"
     CDS             complement(16555..16716)
                     /locus_tag="U2R64_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8918978.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         5411 a         3117 c         3086 g         5117 t
ORIGIN      
        1 aaccaacagt agaaggcgaa aaagtagaag ttgggggcac agtagatcta acagataatg
       61 ttactaactt gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta
      121 caattgatac caacacacca ggtaattacg aaggtgtcat tgaagtaacg tatccagacg
      181 gtacgaaaga tacggtgaaa gttccagtag aagtgacaga caatcgttct gacgccgata
      241 aatatgaacc aacagtagaa ggcgaaaaag tagaaattgg aggcacagta gatttaacag
      301 ataatgttac taacttgcca gcgttaccag aaggaacaac agtaacagat gttactcccg
      361 gcggtacaat tgataccaac acaccaggca attatgaagg tgtcattgaa gtaacgtatc
      421 cagacggtac gaaagatacg gtgaaagttc cagtagaagt gacagacaat cgttctaatg
      481 cagataaata caatcctgaa ggacaaaaag tgactacaga cttaaataaa gagccagatg
      541 catctgaggg aattaagaac aaagaagatt taccaaaagg aactacttat gcttggaaag
      601 agaaagtaga tgttagcaca gctggaaata aaaaaggtac tattgtagtg acatatccag
      661 atggatcatc tgatgaagtt gaagtagacg ttacagtgac agatactcgt tccgatgcag
      721 ataaatataa tcctgaagga caaaaagtga ctacagactt aaataaagag ccagatgcat
      781 ctgagggaat taagaacaaa gaagatctac caaaaggaac tacttatact tggaaagaaa
      841 aagtagatgt tagtacagct ggaaacaaaa aaggtactgt agtagtaaca tatccagatg
      901 gatctaaaga agaagtagaa gttactattt ctgtagtaga taaaaaagca ccgaataaac
      961 ctcaagttga tcctattaca gagggtgacc aaattgttac tggtaaaact gaaccaaatg
     1021 cagaggtgac agttacatta ccagacggaa gtcaacacca tgggacagct gataaaaatg
     1081 gtaattttac agttaaagtt cctaaattag aggcagggac aaaagtgata gtaactgcaa
     1141 ctgatgaatc tggtaatact agtgaaccta ctaatgtagt tgtttcttcc aacaaaaaag
     1201 acagtggaaa aaacggtagt aaaggtagta agactgacaa tcaaggtagc aacagcaatc
     1261 aagacaaaaa tagaggcaaa agccagtcct caaaagtttt tcctaagacg ggagagagtg
     1321 acagtaatat ctttactatt agcggtggtt taatactgtt aggaacgtta ggattattag
     1381 ggtataaaaa tcgaaaaaaa gagaatgaat agaaaatcaa tttcttaagt cttctctgag
     1441 aagaggaaga atctttttct tcctcttttt gcttttttat gatgggaaat aagtgttagt
     1501 taaagatgaa tatacttttt atagaaagga aaagaatgta attaagtgga aaaaatagta
     1561 attattggtt caaaccattc agggctagcc gcagctcgat ttctaaactt aagcgattca
     1621 aattatgaag ttattctaat cgataaaaaa tcagaaatta gttacttgga atgtgggaca
     1681 tcgttattta taaaaggaga agtaagtaat ttagaagatc ttttttatca aaatagaatg
     1741 acactaaatt ctgagataaa aaagttattt ctagagacag aagttgacaa aattgatatt
     1801 caaaataaaa agattagttg tgtaaaaaaa gatggtacaa gattctctca agaatatgac
     1861 aaagttatat tagctacagg ttcaaagcaa attatgctag atataccggg gaataattta
     1921 gctaatattt tttcgataaa gaattttcca aatgcaaaag agatttttaa agctttggat
     1981 gatagtacta ttaaaaaagt aggaattatt ggagcaggat atattggagt tgaaattgct
     2041 gaagccataa gaaaaagagg gaaagaagta tatcttttcg atgttgcaga tagagtgttg
     2101 tcgacttatt acgaccgtag tttttcagat aaagttgaag aaatactatc aaaaaatgga
     2161 atacatcttt gtctatcaga aagtcctaaa aaatatttag gaagaaaaaa gattgaaaaa
     2221 atagtcacta caagtggtac ccaatactct atggatatgg tcgtacaagc tataggattt
     2281 ctatctaata gtccaattgg ggaaaaggaa ctcttgagag atgttagtgg agcatatcta
     2341 actaatgaat accagcaaac aaatataaaa gatatatatg ctattgggga ttgtgctaca
     2401 acttttttta cgtccattaa tagaagtagt gttgattttt ctatttctaa tgctctaaga
     2461 acagcttata ttgcaactca acatattaac aatcaagatt ttacaccttc tggttcccaa
     2521 tttacaaatg gcttttctat atttaattac aatttttacg cagcaggttt gaatttaaaa
     2581 acagcacgat tattaagtga gtctatagat tatatagaaa tagaagattt cattagacct
     2641 gcttttttga gaaaaaatag tcgtgtaaaa ttaagaatta gctttgaaaa aaatacaaag
     2701 agaatagtag gtgtacaact ttgtagtcaa gaagatttat ctggactatt atcaatgttt
     2761 tctcttgcta tagaagaaca aattacatta gacaaattga aaatgttaga ttatttattt
     2821 catcctagtt ttagccaacc ctataatttt attttaaagg cagtaacagg attaaacatt
     2881 gaaacataat cgttactaaa tgaaatcaag aaatatactg tattactcaa ttcattgaaa
     2941 atatttatca taatttttaa tagaaaacac tattaaagag aaaaaagaga ggtaaatcaa
     3001 atgaaaaaat ctttaaaact tgcatcagca gttatattaa tgtcccaact ccttatagca
     3061 acacctttcc atgtgttggc aagcgaaaat tcaacataca aaattgcaaa agaaagaacc
     3121 gagacgactg aaatgagtaa ttccgatgta acagcagaga gtagtgaact tttgacaact
     3181 tcatcaagtg aaagtagtac gacttcaaat gccgagtctt caacaacttc atcaagtgaa
     3241 agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag tagtacgact
     3301 tcaaatgccg agtcttcaac aacttcgtca agtgaaagta gtacgatttc aagtaccgaa
     3361 tcttcaacaa cttcaagtag tacaagtgaa ataacttctt cgaaagtgac aaaaccaaac
     3421 catatagaat cttcaaaaaa ggaagcgcca aaaacggaag gacaaacaaa aactttttcg
     3481 acaccacagc aaatagaatc aacagaatct ttccaatcac aaccaatact atctggtaat
     3541 gaagaaattc attttgacaa aaatgaatct gtagaaaatt ttattatgaa aattggtgag
     3601 tctgcgagaa aaattggtca gaaatatgat ttatatgctt ctgttatgat tgcacaagcg
     3661 atcttagaat ctgccagtgg tcaaagccag ttagctcagg caccgaatta caatttattt
     3721 gggataaaag gaacttataa tggaaacttt gtcattatgg taacaaacga agatttgggt
     3781 aatggaacgc tttatacgac ccaatcaaaa tttagagtgt atgaaaacta tgaggaaagc
     3841 tttgaagatt atgccaaatt attaactaag ggaattagtg gaaataaaga tttttatgca
     3901 ggagcattaa aagctaatag taaaacatat cgagaagcaa ctaaattcct tacaggacgg
     3961 tatgcaacag atacacaata ctatttgaag ctaaatgaat taattaaaac ctacgattta
     4021 accaactatg ataaagaagt taaaggtcca caaatgagta agactggata ccaagtgcct
     4081 attcataatt attcaataac cagtttgttt ggaaatcgtg gaaatgaatt tcaccgagga
     4141 cttgatatgg cagctacaca gggtgagccg attcatgcag ttaaagctgg taaggttgtt
     4201 aaagcagagt ttcactactc ttggggaaat tacgtggtga tacaacacga agatggatca
     4261 accgcgttat atgctcacca gcaacaatac ctagtaaaaa ctggagataa tgttttgcaa
     4321 ggacaaataa ttggctatgt aggaagtact gggaatagta ctggcccaca ccttcatttg
     4381 gaaatttgca aagatagtag tctttctcag agcatgttag ttgatccgaa aaccttatta
     4441 ttcggagact aaaaaaggta atcaatctga caaagtaaca agaaaatggt tggattctta
     4501 gacctttgat caggatattg agactggaat tgatatctcg attacgatgg gtttgacaaa
     4561 taaaacaagt ccattatcga atatcgagtg tattattgcc gtctttatgc tcatattttg
     4621 agcaggtttc actagatgaa aacaatttat ctatcttgag gatttcgtgt acgtatcgtt
     4681 cagtcttgta ttgtaaatta gtcataaaat cagactaaga aaaattggaa atattttttt
     4741 ctgatttatt aaaagttaat tgaaattata tggtacttct ttcttgggag ggtaggtgca
     4801 gtgaaggaaa gatatggtca ccttactgtt gttgaggaga ttactcataa tggatataaa
     4861 aaatatcgtt gcctatgtga ctgtgggaat gaaacgattg tatatcgatc aaacttacta
     4921 tcaggtagaa ccaaaagttg tggatgtgga aattataaaa ataggcataa atataaaaat
     4981 ttgacaaata aaacttttgg taagttagtt gcaatcaagc caactaaact gcgaagtgaa
     5041 ggaactgttg tttgggaatg tcaatgtctg tgtgggagaa aaaagttagt atcggcaaag
     5101 cgacttctaa aaggtgatgt aaaaagctgt ggatgtttga aatcaaaaaa gcatcacatt
     5161 gaaaataaaa aattcggatt acttactgca aagtatcctt tggacaataa ctgttcatgg
     5221 aaaacaaaat gggtttgtca ttgtgagtgt ggcagtatgt gtgagataag ttatagtaac
     5281 ttattttttg gacatactca aagttgtgga tgtttaaaaa ggcaagaaac aaggacatgt
     5341 gttgaaggga cagtaataga gtgtctaacg tcaaaattac cgaaaaataa tacaagtggt
     5401 gttaagggag tttatcgttc taaagagaaa tagattgcgt atataacttt aaaaaaaaag
     5461 aggtactatt taggatcgta tgattctatt aagagtgcag ctcaagctag aaaagatgct
     5521 gaaaataaat tgtttcaacc tttgattgac aaatatcgag gtaatcatta attattgtgg
     5581 ataataatta acagtgatat ataaacatct ataatatatt attcatacta ttgatattta
     5641 gtataatcct atggaattga atatcatagc aatgtatttg aaaagcaaat tggaaaacaa
     5701 ataggtgcaa caccataaat atgaaaaaat tgggaaaaag tagaatggaa atttgcttac
     5761 gtctcacgag atagctcaca ctattaatct gaagaacaat gaagtcgact tttagaaatt
     5821 gctagaagaa agtaaagcga attatcacta gttactatag agtaagttca aataaagcat
     5881 ctccaactta catggttaca tgaggatatc aaatcgaaat tactcaagct tcctatggct
     5941 agagtcgcga gaagttgttg ggcagtagac ataggttata ttgttcttag ctacacgatc
     6001 attagaaagg aaatcctatt atgtatagtt atcaagaaga tgcaaaagtc caaaaaaatc
     6061 gctggtggat tttgattgct atatctatgt ttaccttcat gtccacattg gatggcagta
     6121 ttgtcaatat tgcactacct accatctcag atgatatggg cataccaatg aatcaagcgg
     6181 aatgggtagt gtccgtttat ctgatgattg tctgttcttg tttgttgctg tttggtaaaa
     6241 ttggcgatag ccgtgggaaa atcaaagtat ttcggattgg tacgctgatc tttgtcttgg
     6301 gatcgctgtt gtgtgggttc aatcattcgc taggtatttt attgttcgca cgggtggtac
     6361 aagccattgg tgctagtatg actatggcta caaatgccgg aatcatcacg gaagtctttc
     6421 ccatacatga acgtggtcgg gcattgggag caataggtgc gtttgtttca ttaggctcga
     6481 ttgctggacc aggtcttggc ggcttgattt tgtcccaatt ttcttgggcg tacatttttt
     6541 ggatcaatgt accggtggga atcgtaacga tgttgattgc tgaaaaattc ttaccaaaag
     6601 atatcaccat gagcggccat acaatcgatg gagggggctt tgctgccatt gcggctacga
     6661 ttatcagctt ttttggagca atctttttgg ggcaagaaag tggctttttc catccagtcc
     6721 cccttgtact gttcgtaatt tcagtgattg cctttgtcag ctttttaaaa gttgaaaaga
     6781 aagcagcctc tccattgatt tctttcggta tttttaagaa caagattttt accatgagct
     6841 tgattacagc cttgttgatt ttttcttcca acttctttgt caatgtagtg attccttttt
     6901 atctgcaaaa tgctcgcggg ttgagtccta gctatgctgg gctgttgatg atggtctttc
     6961 ctttgatgat ggtcgtcggg gcgcctttaa gcggctacct gaccgaccgg gttggcccgg
     7021 agattttggt attagtaggc ttgggcttat tgtcggtaac ccaggtcatg tatatgtttt
     7081 tgtcagtgga ctctcctttg tggctataca ttgtcgctac tgccatcatg ggtgccggca
     7141 atgccttgtt ccagtccccc aataatacga tggttatgag ctcggtcact atcgaaaact
     7201 tgggactggc aggctcgatg aattcctttg cccgaaattt ggggatggtc agcgggattt
     7261 cgctttctac gacggtctta tatcaagcga tgtctgctaa gatgggccag caagtaacta
     7321 actatatcgc aaatcggccg gatgtctttt tatatggaat gaagattacc tttttaggca
     7381 gctttgtttt gtgttttgtt gcctttttcc tgactatctg gcgtatcaaa aaacaaggag
     7441 gtattcagaa aaatgtctga aaaaaccact gttgaagaat ttttggaggc ctgcgtatgg
     7501 gtgagtggga tttccatgga tgatggaaga tgaagtgaac ttctaaaagc cgaaaaactc
     7561 aagtattatc ttcaaaatac tagtgctcaa tgagatgctt gatttgatca caagaagact
     7621 gcgaaagccg ctggcaaccg caagctaggt atcccaccga tggactacgt tttagaggct
     7681 actggttatg aatacggagc caacgctctc atctgcataa gaatacatca cccagattat
     7741 gtaaagattt tcgatacttc tgtcaaaaaa tcattaagat agataaatga tttccgtcta
     7801 gtcaaattgg ttcagaatgt agacacacag atggtaagaa gtcactcaca attcgagaat
     7861 ggacttgtcc tatttgccgt atacatcata atcgaaacgt caacgatagt atcaatattt
     7921 tgaccaaggg ctatgaatac aagcattgcc ttagaaaaca tcaagaacct taggaacaac
     7981 ggggatagct tggttaataa gagataccgc tgtttaggct tgcaagtata ctcttttatc
     8041 aagaattccg tggctttagt catgagaggc ttaatactat gaaaattttc tttagcattt
     8101 ttgatttagg ttccttttct aattataata agatgaccac tacagtaacc tactgaaata
     8161 tataaacagc cactgtagta ccattttcaa agtagtctat gagaggagaa tcttcattct
     8221 tatgaacgct ggaattgcgg atatgaattt aataaaaaaa acccttaatg attttacttc
     8281 caattcaata tcaaaaggta ctggtatcaa tttaagcaca ataaaaaagc tgaaaagtgg
     8341 tgaaagatca gtggaaaagc tgaatctttt agatgctata aaaataacgg aatttgctat
     8401 gaaaaatgga aaagctgaga ttgaaatatg gagataatta tcgtctagtg aattacttgc
     8461 cacttagctg aatttaacga tccttggtgc ttgaaggggg agattcttgg gaatagagca
     8521 tacttgcaag cctatgtctt tactaacaac gatatctctt attaaccaag ctatccccgt
     8581 agttctaagg cttttacttt tatctaagca ataatcgtat tcaaaggaaa tttttgaccc
     8641 ttagaaagtc tcattttatc agacgtgagc ttaggcattg ctgaattttg ttaattcggt
     8701 tttaggttgt gctttgagca taatatgaaa gtattcttta tcacgatttc attcatctaa
     8761 ggtaatgtga tgtgattctg aaattctttc aaaggcagtt tttgcataag ctgacattac
     8821 atcatcaatg acatgtttac aatgtttcac tactaaaata agggggtaac caagaagaaa
     8881 aactgaatga ttatttgtat ctaattccat ggtatatcaa ccatttccta tatagactga
     8941 ttatgacatg gattaaaata aaaaggcact atgtcttaat tgtcggtttt cgagttaccg
     9001 aatggcattc atcacccacc tatagaggat gggcgacttc tgcctgaaat aagttacact
     9061 acttataact tctaataaaa ttagattgag tcattattat ttaacatcaa cgattttcca
     9121 gtttccattt ttttgtaata ctaatttgta ctgaaagtag ctagtggttt ttgatacatt
     9181 atcaaggtat tttatctttg tactcactag aaaatttttt ccgttttgta gataaactgg
     9241 attctctaac tccgaaaact ttaagtcaat attgattggt cgcatcgcac cattttcaac
     9301 ataatactcc aattcttttt cagaagctga tggataaagt ttaaaaaatg tttctaaaaa
     9361 atcggtgatt tcttccgttg ttttggcatc aatttctgaa tcgttttcta cttgttttgc
     9421 ttcatatttt gccttgtctg gctttccaat cattgttggc aaactagtta ctaaatgatt
     9481 cctgttttca tcttcaaaga ttgtcactcg atatgcagaa gaaattgatt gcgtcttttt
     9541 tccctctgta atatgttgct ccactaaaaa tgaaacgaca aattcttccg agtgtttttc
     9601 aacatctaga atttttacag attgaacttc ggaactcgtg ggaatatctg ctcgaaccat
     9661 atcttggatt aaagcgagac cgttttctgt aaggtactgt tcgagattac tcattctctt
     9721 ttcaattgct tctttgttat ttttccatga aaaatattct ttcgcaaaat cctctgtaaa
     9781 actttcaacg ccagaagtat tcactacctt ctcttttata accacttttt catgagttgt
     9841 atgttgatca atggcggtga aatttttata aacgccaaaa gcaagactac aagacaataa
     9901 aagccaaagg gcaagcacca tttttcgatg cttacccacg gatacaactc gttctttttt
     9961 cttttttggg ctcttttcct tttgattccg ttcaattttt atcttcattc tttttcctct
    10021 tttctcttat ttgtatcggc cagctccgat aagatgctgc cgccaatagt tttccgttag
    10081 attcgtccac cccactggat ctcctgcatg aaacatgcga ttctcccctg cgtaaatgcc
    10141 cacatgggtc acataagtac cggcatcata ggttgaatga aagaaaacta aatcacctgg
    10201 tttggcatct tttagatcaa tatgagtcat ggcatcatat tgatcctgag ccacccgagg
    10261 aagtttcagg tcaactttgg cataacacca ttgggtcaag ccactacaat caaaccccgt
    10321 ttctggactt gagccaccaa acacataggc cgttccttca tacttaaatg cctcatcaaa
    10381 aatttcttgg actattttgt catcaaactg agttgtagtt aggtattgct tcactaataa
    10441 acagtaaaac atattgccat aattataccg ccacccacca ttttccttaa tcgcgattgg
    10501 gttggggtaa tcgacttttt gaccacctga tttttccttt gaaaaagatt cagctaaagc
    10561 aaaactatgc ttcttcccgt ttttcccgac atgatctaga tacccgccac catagttata
    10621 ggcctgaata atactatctt gatcacaccc tagttctttg gaacgcttaa ccaaagacgc
    10681 aaaatagaga cagccttgtt tgatggatgc ctcggtactt aatgaattag gtggtaatcc
    10741 ggctgactca gaactttgca taacgtcttc cattgtgcca ccagattcca cttgaataat
    10801 cgccaaaaga attggaatat actctgttat atccgattct ttggcatact tttccaccat
    10861 tgcacggtgt ttcaatactt cttctgagac actagttccg ccaggagaag tgccagaact
    10921 accatttccc tcactgtctt caccaaacaa caaacccaca cacatcaaaa tacccataaa
    10981 agagatggtc agaaaagtta atgaaataac acccactttc ttcaagttca ttttttctca
    11041 cctgaccttg attttggacg atggttcatt cttttttgta ctttttgatt ggtctgcttt
    11101 ggcagagtgg acctctgttt cacttgttgg aaagaatttt tcttacttgc tgattggctt
    11161 ttcccttttg aaatgatttc ttgactagtt agttttcgtt tgatttcggg attcagattt
    11221 gctctcacaa tccgctttgg tgcttctttt ttcagcatca tatctttctg aggttgagct
    11281 gctttatcta ttggaatatt cgcccttctt tttccctgac gatttgttgc ttcactcagt
    11341 atcttgcgtt tttcgtccat tttcgcattt cttcgttgtc gttgtttttc tcgcaaatcc
    11401 actcgatccg ctttttcttg gaacagtccg cgcttgaatt cttctggtgc ttttttcgac
    11461 ttttcgattc ctttatggag attgtatttc aaattcgttg gcgtattcct tacctgatcc
    11521 tttacttgtt tagtcttatc tttcaccaaa gcttgggtat ccaaaacttt gccgattttt
    11581 ctcccagcca aattcattcg ggattgtttc ttattatttg aaactggatt ctccttagtt
    11641 aagtcagata gtatttcgtg atcgttcggt aatcgtgaat tctttcgtag agaagaaccg
    11701 gatggcttaa atttggattt tgattgttcc tttgccaact tatttccgac tgctgcacca
    11761 ccaccaaaag ccaaagctcg tcccacattt cgattgagtt gccgcaattt tcgattcatt
    11821 aacatttgcg gttttcgcat gacgcgtctt cccattgact ggctatcatt actctggagg
    11881 ttgaacatac tcataatgtc gcccaatttg aaatagatac cggcaaaggt cacaatttgc
    11941 agaaaagcaa ccatgaaaaa tggataggtt gccgaaatat tgaaaaacat cgtggagatg
    12001 ctaaatgcag tcgtaatcac caaagtaaca cccgctcgca tcataatcgt attgaataaa
    12061 cgaataatcg ccttctttcc taaactttca taagtcggca acatggacaa taagaaacta
    12121 attggcagaa acatcgcaaa gataatgaag agaatttgcg agaacaacat aatccctgtt
    12181 agaagaaaaa caaagaagga aatgccaata ttgaacaata ccaaaaagac cacggtccct
    12241 aaacggttca tggtcttggt aatactgaga ttcgcattgt cattgtcttc aatctctgcc
    12301 ttgaccgctt cttcccgatc tttgcctttg ttttcatctg gactcacaga tagaatcttg
    12361 ttgacccggt cttcaccaat ttcttctatg ttggaatcat caaattgcag tagtaaccaa
    12421 ggttgttgga cttgaatcga aaacaaacta tcccgaatca aatccacact atcttttcct
    12481 tggctttctg aattgggtac aacgatctcg gttccaaggg taagggccgc ttcactaaca
    12541 tctgagctaa agtcattgat ttttgtgata taggtaggcg cataagcaat gaacgaaccc
    12601 gatagtagaa aaatcatcac aaaattaatc acggctcgaa ctgctttcgt ggtttctcgt
    12661 tttaataatc cggtatacgc cacatacacc cccagagcta aaatcatcaa taatagaaac
    12721 ccaaaataaa atccggaggt ctggagtcca ttttcagtaa taccagccaa tgtttggata
    12781 ttctttccaa tactttcagc cgtatccgaa atgaaatcta atttgtaagc ctcttgaacc
    12841 acataacccg tggcgttcga caaatacaaa ctcaccgtcc aaatgaaatt agtaatggca
    12901 taaagaccat acatcacgct tttccctaag ccatcacccc aattccaagg caaccaatcc
    12961 caagagctat ccacaaagaa atctagttga tagttgttca gtgaatattt ggaatataga
    13021 tttcctgctt caactgtatc atcaactagc cctgtcgcct cggctaccgt accaactaaa
    13081 ctcaatagaa ctatcagagt gagtatgcta ataaaaacga ttcccacaat ccgaaaaagt
    13141 ttctttttca tcccctcact ccattctctc ttgaacaggt ggacgggtat caaaggcatg
    13201 gaagagttct tcaaagactg gatgtacctg aaccacgcct acccgaccat acaaatcctg
    13261 catcaagcat tggccatttt ccaaatctcg taggcgtttt tgattgcttt catcttctcg
    13321 atccaagcca aagaattcca aggttttctt gatttcatga atatcggtac tgcgaaacgc
    13381 aaacttcaac ccgatattat tcttcaagcg ttcatccagt aaatcatcac tattttgcgt
    13441 gacaaagtaa accccggcat tcatagcccg cccagcacga acgagcttat tcgataatgt
    13501 tttcccttgc gctacttgaa gaaaactcca cgcctcatct aagtctacaa ttttgaagat
    13561 ttctcgatta ctatggataa agtccaaggc aaaagtggaa atgacgatta gcatggaaac
    13621 actaagcaat tccatggtgg tatattcttc aaaagtggtt tctgcatctg gtaaaaccaa
    13681 atccgctact tgaatgatat ttaactgcct atctaaacta atcgactggg taatcgaacc
    13741 atctgagaaa agcaaatggg caaaatcata atcggtaaag gactcgatgt gatccgcgat
    13801 attttccgca actggtgagc cttcttttcg aagctcatta attacttgta ataatccccg
    13861 ttgattgctt tgggtaaccg tccgaatggc cttacgcaac actggaaact tctccccatc
    13921 tcgactagaa attcctgtta aaaaggtcag aatatcaatt gctagacttt cagaatcctt
    13981 ctttttctcc ataatcacat aaggatcaag taatccttga ttttttggct tactagttaa
    14041 gttgagaata ttgatttcat ccgcaatttc tggcaaggtt tctttccagc caccccgttc
    14101 cccttttgga tcgacaatca cagcttgtcc accaaaaagg acggcgtaat aaactaagag
    14161 attgttacta aaggactttc cgccaccgag tgaaccgagg aatgccgctg ctagcgcatt
    14221 ggtaactgaa cccttgaccc cttgtgaggc caatgccggt ttcaggtaaa cattgcgccc
    14281 cgtatctacg ttataaccaa agtaaatgcc ttccaactcc cctaacatct gagtggcgcc
    14341 aaaaccaagt ccggcgagaa aatcagacgt aacatactgg atataatcat tcatgtatcg
    14401 cttactagaa ggtaagaatt cttcatgtag ccccatcata tcgccaaaag gccggactag
    14461 ttttacattg gtatcatcat aaaaatctag cacttcatca caccggcgct ttagttcatc
    14521 tactgattcg gcacttactc gaaccacata gctcagtttg tacatggatt ctttggactg
    14581 atccaaggta gtttccaatt catctacgga atccaatgca tctaagacat tggaatttgt
    14641 ttcattgtca gattgatagg catggttgtc caagtctttt aattcctttt tcttattgcg
    14701 aacggtagca agtgcctttt tgttcgtcac aatctccaca ttcatactag tgtcaattgg
    14761 gaatgtaaat tgttgttgct ggtaatagaa aagttctgag gagggaaact ccatttcccc
    14821 cacaattgta ttaattgtta agtacgctac atatgattca tgattctcat gttccatgca
    14881 taagtaccgg ggcttttctt caatcaaaca acgactggga cgtaataagt cgtaacgttt
    14941 caccaaagtt tccgacttca gctttttctt tggtagctga aattcatatt cttcaaatgg
    15001 tgtacccttt tcgccataga tatgttcaat caaatacatc agatcactcg gtgtgactcg
    15061 tctgacttta aatcttcgag ccaatttact ttccattagt ttttcaagct tggtatatcg
    15121 gcgaatttct tcattggata aggaaacaaa atcgcccatc aaatgatgat tcactccata
    15181 gacaaattct tgaaagccgg agaagaaaga tttcttgaga ttctttagat tgacctcttc
    15241 atctgtcgca atcagtttga agccaataaa aaagcgataa tcaatctgac tatcgccaat
    15301 catggatact aatgcctctg tctgtaaatc aattcgttgt ttcgctactt ctgttaatcg
    15361 cccggtaatt tccttttttg atcgttcttg cgtggcacga atactacttt ctgtggcaat
    15421 ttgtaaggca tgaatcttgc cttcacgatt ttgcgcaatc aattgacgaa agttatcgtg
    15481 gacttgatat ttctgttcag gtgacaaaaa ggagtaattg taaggtatta actcatagta
    15541 ggcaaaacat tctccctctt gattaaagac aagattattt tcaatatact taatcgggta
    15601 catagttcac actccttacc agagtaatgg gttcgtccca tcgtttcttc tgttctttga
    15661 ctttctttcc tgcgaaagtg accttaaatc gtaagtgata gctaataaaa gatcgtaaaa
    15721 atcccaatgg tttcttaccg tcaaacgttt tttgcgacat gaaccaagta actgccaccg
    15781 gtatacctaa gtattttaaa aaggccccct ctatcataga tagtggaggc acatgggcaa
    15841 atacgatgac aaacagcaag gataaaacaa accaagccat ctggttaaaa gtcacaggaa
    15901 aaggcagttg aaagtcatta attgcataaa tgaccttttc aactgcccaa atactggtgt
    15961 agctttttat tttcttcatc aaatcattcc tttaaaaaga aggatagttt agaaatcaac
    16021 tacccttcaa taattttgtt aatatggata ctcaaaaaca cctcgactcg ttaccaaata
    16081 attgcctcca atctccaagt ctctaccaca cgcatcaaaa tcaatatacg tcttcaagtg
    16141 ttctggtact tctccaaaat caccagcttc tacaatcaag aaatatgcta catcactcat
    16201 atcatcgcaa tctggataat agataatatc atccacatgc tctaccatct cctcaaaaga
    16261 attgaagaaa gcatgttgaa tctcagaagc aacttcacca actggcgttc cttcaagttc
    16321 ctccgctaag ccacacaacc gattaatttc ctcaattggc gtatactcat caatctcaaa
    16381 gggaagttca taatcatgaa ttgcatattc ctcgtattcg tcatttaacc caattcgttc
    16441 tttcacttca tcaaaatcga caggtggggt aaaccacgcc cccaccaatt caccttcgtt
    16501 atatttcccg aggttcgcaa tataaacacg catctgttcc atcgtgcttc ccccttacgc
    16561 accgacaatt cggttaaaca aactgagtaa gacatccttc accccagaag cattaaagac
    16621 caatccgacc gcaatcaaag caatcaccaa aaagccaatc agtttggaaa actcccgctt
    16681 aaatcctaaa aacaaaccaa tgaccacaat tgccagtaag actaaggatt g
//
LOCUS       DASHWW010000062        16700 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.062, whole genome shotgun sequence.
ACCESSION   DASHWW010000062 DASHWW010000000
VERSION     DASHWW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.062"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            176..403
                     /locus_tag="U2R64_002187"
     CDS             176..403
                     /locus_tag="U2R64_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEM8918979.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            419..1585
                     /locus_tag="U2R64_002188"
     CDS             419..1585
                     /locus_tag="U2R64_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEM8918980.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            1820..2863
                     /gene="hrcA"
                     /locus_tag="U2R64_002189"
     CDS             1820..2863
                     /gene="hrcA"
                     /locus_tag="U2R64_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEM8918981.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            2957..3520
                     /gene="grpE"
                     /locus_tag="U2R64_002190"
     CDS             2957..3520
                     /gene="grpE"
                     /locus_tag="U2R64_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEM8918982.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDRYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            3571..5400
                     /gene="dnaK"
                     /locus_tag="U2R64_002191"
     CDS             3571..5400
                     /gene="dnaK"
                     /locus_tag="U2R64_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEM8918983.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGKRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            5551..6717
                     /gene="dnaJ"
                     /locus_tag="U2R64_002192"
     CDS             5551..6717
                     /gene="dnaJ"
                     /locus_tag="U2R64_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEM8918984.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(7085..7822)
                     /locus_tag="U2R64_002193"
     CDS             complement(7085..7822)
                     /locus_tag="U2R64_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8918985.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(7824..9326)
                     /locus_tag="U2R64_002194"
     CDS             complement(7824..9326)
                     /locus_tag="U2R64_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEM8918986.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIEKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            9585..11579
                     /gene="uvrB"
                     /locus_tag="U2R64_002195"
     CDS             9585..11579
                     /gene="uvrB"
                     /locus_tag="U2R64_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HEM8918987.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            11589..14405
                     /gene="uvrA"
                     /locus_tag="U2R64_002196"
     CDS             11589..14405
                     /gene="uvrA"
                     /locus_tag="U2R64_002196"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEM8918988.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            14668..15933
                     /locus_tag="U2R64_002197"
     CDS             14668..15933
                     /locus_tag="U2R64_002197"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HEM8918989.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYAGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            15937..16668
                     /locus_tag="U2R64_002198"
     CDS             15937..16668
                     /locus_tag="U2R64_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HEM8918990.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
BASE COUNT         5504 a         2901 c         3661 g         4634 t
ORIGIN      
        1 tttttatgaa taaaataagg acaaaattgt ttaggaagaa tcatgagtgt aaaaaaatca
       61 tccaagaagt cgattcttgg attttttagt ggatttgttc gccaaatacg tttagtatgc
      121 gtatatgaga ggttgtaagc aaagcgttgt ggtctgagca cttaaggagg aatctgtgaa
      181 aatagctttt catatttttg cagattttga cttaatgccg aaggtcagct ttgcgattac
      241 cgtttatcga gaggctgtaa aagcaccgtg tagctccgat gacaataagc aagcattttt
      301 agagctaggt ttccttgatt ctaaatatgc ggcttatttc aatgagttgg tgcttgaacg
      361 cgattttaag aaggtcgaaa acaggcacga cttttcgacg taaggagaaa gaatttcaat
      421 gatagaaaca ataaatcccg cagaaaacaa ggtttctgcg tacattcata tcccattttg
      481 cgagcatatc tgctattact gtgactttaa taaagttttt ttagaagggc agccagtaga
      541 tgagtatgtg gaaatgctgc tgaatgaaat gagattaatg ctggaaagtc atcctacagc
      601 gaatttggaa acactttatg taggaggcgg aacaccaact tctttatctg ctaaacaact
      661 tgatcgacta ttatcaggtg ctagagagat cctgcctttt caaaatggta atgagtttac
      721 tgtagaagcg aatcctggtg atttgacccg tgaaaaactt caagtgatga aaaactatgg
      781 cgtcaatcgt ttatccatgg gagtgcagac atttgacaat cgcttattga aaaaaattgg
      841 acgtaaacat actgcagaag atgtgtatca aacaatgcaa tttttagaag cagaaaattt
      901 taccaatgta agcatcgatt tgatttatgc attaccggga caaacactag aaggatatcg
      961 ggatactttg gaaaaagctt tggctttgga tctgcctcac tattctttgt actcattgat
     1021 cctcgaaaac aaaacaatgt tcatgaactg ggtacgacaa ggaagactcg aactgcctga
     1081 tcaggaaacg gaaaccagaa tgtttgaaga gacgattgaa gcaatggaaa agcatggacg
     1141 tcaccaatat gaaataagta actttgggct ctccggacat gaatctcaac ataacctcat
     1201 gtactggaac aatgaccact attttgggtt tggagctggt gctagcggtt atcttggaga
     1261 tattcgttac cgcaacaaag gaccgatcca acactattta cgcccattac gagcaaatga
     1321 acgcccggta ttggaagaag aaaaattgac acgaaaaaat caaatagaag aagaaatgtt
     1381 cttaggacta agaaaaaaaa cagggattac taaaaaacat ttctatgatc gctatcaaaa
     1441 aacaattgaa tcggtgtacg gtgatgtgct aagggaatta gagcaagaag ggttacttgt
     1501 taatgaagaa gaccgtgttt atttgacacc aagagggact tttttgggga acaatgtgtt
     1561 tgagcgcttt ttatttgaaa aatagtttga agaatatttg ttttttatcg aaacttgaaa
     1621 agaaaaagtt tagaaagttt gacaatgagg tattgaagta ttgatataac tggatttaca
     1681 tcaattattt agaattagca ctcttgtgtt tagagtgcta aaaaatggag tctttctctt
     1741 gacaggagaa gggcttcttg ctatatttat aagtgaatta gcacttagaa tatatgagtg
     1801 ctaatgagag gtgaggaaga tgttaacaaa gcgacaaaac gacattttac gtctgatcat
     1861 ccaacactat acgagtagtg gcgtgcccgt tggttccaaa acattaatgt ctgagggagt
     1921 caaggccagc tcagcaacga ttcgcaatga tatgaaagca ttagaagatg aaggattgct
     1981 gttgaagact cactcttctt ctgggcggat tccatctgct ttaggctatc gttattacgt
     2041 ggatcatttg ttaaaacctg ctcgcgtagc agaagatgat ttgctgctga ttcgtcagtc
     2101 tctaggcaga gaatttcatg aaatcaatga gattattaag caatctgctg agatattatc
     2161 tgagctgaca agctatacga ctttttcatt gggacctgaa ataaaagacc gccgactgac
     2221 tggctttcgt atcgtaccct tgaataatcg acagattatt gctatcgtcg taacagatat
     2281 ggggaatgta gaaagccaag tgttcactct tcccgaatat atgggaagtc aggaactaga
     2341 aaaaatggta cagattgtaa acgaccgtct agtcggagat cctctgatga cggtgtacca
     2401 taaacttcgt acggagattc cgatgattct tcataaatat ttccagacga cagaagggat
     2461 gtctcagtta tttgacaccg ttcttggtca tgtttttgaa gaaaaggttt atgtcagtgg
     2521 acaaatgaat ctcttggatt atgagccccg tcaagatctt gatcagttca aatcgatgtt
     2581 ttcttttatg aaagactcag acggacttac acaaatgatc actccgatgg atagcaatat
     2641 tcatatcaag attggtgctg aattaggcaa tgatttattg cagaatatga gtatgattca
     2701 agcaagttac gagatagatg gtcatggaag aggtacaata gccttgttag ggcctactag
     2761 tatgccttat tctcggatgt tcggtctagt cgatgtttat cgaagagaac tagcagctaa
     2821 acttgctgat tattaccgct cgcttgactt gtcaaactcg taatgtgaat aacgaagcta
     2881 tttgcagctg atcgttctct ctttcttagt aagagcaatc aaacagctga ctgaataatg
     2941 aaaggaagac tgtatcgtga aagaaaatca agaagaacta gataaagaaa tgacagatgc
     3001 tcagccagaa ccggaaatcg atgtcgaagc tgcagaagat tcgggtattt cagaagctga
     3061 agcggaagaa ttcgaaacag cgaaattaaa agctgagtta gaagaaatgg aagatagata
     3121 cttgcgggct cgtgctgaaa tcgcaaatat ggcaaatcga ggaaaaaatg agcgtgagca
     3181 attacaaaaa taccgttcac aagatttagc caaaaaatta cttccatcaa ttgacaacct
     3241 ggaacgtgca ttagccacag aagtgtcaga tgatcaaggg gcaggtttga aaaaaggcgt
     3301 ggaaatggtc ttggaaagtt tgcgtaacgc actggaagaa gaaggaattg aaaaaatccc
     3361 tgctaaagga gaagcctttg atcctaatct tcatcaagca gtacaaactg ttccagcgac
     3421 tgaagataca ccagccgata cgattgtaga agtactacaa gaaggctaca aattacatga
     3481 tcgcgtgtta agaccaacta tggtcattgt tgcacaataa ttgtgcggat ataaaactta
     3541 cactttcaat taaagaagga gacgttaatt atgagtaaaa ttatcggtat tgacttaggt
     3601 acgactaact ctgcagtagc agtattggaa ggaaacgaag caaaaatcat cgctaaccca
     3661 gaaggaaaac gtacaacacc ttctgttgta tcattcaaaa atggagaaat ccaagtaggg
     3721 gaagttgcaa aacgtcaagc tgtgacaaac ccaaatacga tttcatcaat caaacgccat
     3781 atcggtgaag caggttacaa agtagatgta gaaggtaaat catatacacc acaagaaatc
     3841 tcagcaatga tccttcaata tatcaaagga ttcgcagaag actatttagg tgaaaaagtc
     3901 gaaaaagcag ttatcactgt gccagcttac tttaatgatg cacaacgtca agcaacaaaa
     3961 gatgctggta agatcgctgg tctagaagta gaacgtatcg tcaatgaacc aactgcagct
     4021 gctcttgcct atggtttaga taaaacagat cgcgacgaaa aaatcttagt attcgacctt
     4081 ggtggcggta cttttgacgt atctatcctt gaactaggag acggtgtctt tgatgtattg
     4141 tcaacagctg gcgacaacca tctaggtggg gacgactttg ataacaaaat catcgactac
     4201 atggtagcag aattcaaaaa agaaaacagc attgacttgt ctcaagacaa aatggcttta
     4261 caacgcttga aagacgctgc tgaaaaagcg aaaaaagatt tatctggcgt atcaagcaca
     4321 caaatcagct tgccatttat cacagcagga gaatctggac cattgcattt ggaaatgaca
     4381 ttgacacgtg caaaatttga tgaattaaca gctgacttag tagaacgtac aaaagtacca
     4441 gtacgtcaag cgttaaaaga tgcaggtctg tcacaatcag aaatcgacga agttatttta
     4501 gtcggtggat ctactcgtat ccctgcagtt gtagaagcag tacgtaaaga aacaggaaaa
     4561 gaaccaaaca aatcagttaa ccctgatgaa gtagttgcta tgggtgctgc tatccaaggt
     4621 ggcgtgatca ctggtgatgt gaaagatgtt gttttacttg acgttacacc attgtcatta
     4681 ggtatcgaaa caatgggtgg agtgttcact aaattgattg accgcaatac aacgattcca
     4741 acaagtaaat cacaagtatt ctcaactgcg gcagataatc aaccagcagt agacatccat
     4801 gtattacaag gtgaacgccc aatggctgct gacaacaaaa ctctaggaag attccaattg
     4861 acagatattc cagcagctcc tcgtggtatt ccacaaatcg aagtaacatt cgatattgat
     4921 aaaaacggga ttgtaaatgt atctgcgaaa gatctaggta cacaaaaaga acaaaaaatc
     4981 acgatcaaat cttcttcagg tctaacagat gaagaaatcg aacgtatggt gaaagatgca
     5041 gaagcaaacg ctgaagcaga taaagctcgt aaagaggaag ttgacctacg taatgatgta
     5101 gacgcattgc tattctctgt ggacaaaaca ttgaaagaat tagaaggcaa agtggacgaa
     5161 gaagaagtga aaaaagcaga aacagctcgt gacgaattaa aagccgctgt tgaagcaaac
     5221 aacatcgagg aaatgaaaac taaacgcgat gcattgaacg aaatcgttca aaacttgact
     5281 gttaaactat acgaacaagc tgcacaacaa caagctcaag aaaatccaga agcagctcaa
     5341 ggcggagcag atgatgtcgt tgatgctgat tttgaagaag tcgatggcga cgataaataa
     5401 tcagttcact gaatttcgag agaaggccaa agttgctact ttggcttttt cttttgaaaa
     5461 atagtttgaa gtatcggttt ttgtttcaaa caaaatatga tatgataaca agcgacgtga
     5521 aaatgatgag aaccaatagg aggaaagcct atggcaacaa aacgtgatta ttatgaagtc
     5581 ttagggctct caaaaggagc atcagaagat gaaataaaga aagcttatcg taagctttcg
     5641 aaaaaatacc atcctgacat caataaagaa cctgatgcgg aagaaaaatt caaagaagta
     5701 tcagaagcat atgagatttt aagtgacccg caaaaacgcg ctgcatacga ccaatacggg
     5761 catgcaggca cagatccaaa ttacggtgct ggtggagctg gtggcggatt tggtggattc
     5821 ggcggcttct ctggtggcgg cttcggtggt tttgaagata tcttcgactc tttctttgga
     5881 ggaggcggtc gatcagtcga tccaaatgcg cctcgtcaag gtgctgattt gcaatatacg
     5941 gtcgacttgt cttttgaaga agcgattttt ggtgtagaaa aagaaatcaa gtataatcgg
     6001 gaagaaatct gtcatacttg tggtggaaac ggtgcaaaac caggcacaca accaactact
     6061 tgtcataaat gtcatggtgc aggtacgatc aatgtagaac gccaaacgcc acttggacga
     6121 gtgatgagcc gtcaaacttg tgatgtttgt catggcacag ggaaagaaat caaagaacct
     6181 tgtccaacct gtcatggctc aggacatgag aagaaagcac attcagttaa agtgaatgta
     6241 ccagctggtg tagaagaagg acaacaaatg cgtttagctg gtcaaggaga agctggagaa
     6301 aacggcggac catttggtga tttgtatgtg gtctttcgtg tagaagaaag tgatatcttt
     6361 gatcgtgaag gttctgaaat ttactatgaa ttgcctttaa gttttgtaca agcagctttg
     6421 ggggatgaag tccaagtacc aactgtccat ggagatgtga aattgaagat ccctgctgga
     6481 acacagacag gtacgaactt ccgtttacgt ggaaaaggcg ctccgaagtt acgtggtggt
     6541 gcaacaggcg accaacatgt caaagtaaaa ctgatcacac cgaaaaatct aaatgaacaa
     6601 caaagagaag cattacgtgc attcgctgaa gctggcggca tcaaagttga agaacagcaa
     6661 gaagacggtt tcttcgataa gtttaaagat gcttttggcg ggaaaaagcg gaagtagttt
     6721 ttctagtaaa aatataaagt agacttgccc aaattttcta tttctagtaa aaacgctaag
     6781 tcattaataa ttaaaaacca gacgaacaat catacgttcg cctggttttt ttgtagttgt
     6841 catgtttgta ccaacaaaaa agccagcttt agaataagat aatcatcata gtttctgaag
     6901 gtggtatcga ctatgtactt gatatcgtca atgaaccgat ggtactttct tatgcgatgg
     6961 aacaggtaga gcgattgctt gtttgtgcag gagaacaagc gatgcggctg gtacagttaa
     7021 gtgaaaaaac aagaaactaa aaatgcccgg tcgtcatgaa gcaaccgggc atttttggtt
     7081 tttattaaat attcaatact ttattcaaga aatcttttgt ccgttcattt tgcggatttt
     7141 caaagatttg ttgaggcgtt ccgtcttcta aaaagtttcc gtcgtcaatg aacatgacac
     7201 gattggccac ttctttagcg aagcccattt cgtgcgtaac gataaccatc gtcatacctt
     7261 gttctgctaa ctttttcatg acgttcaaga catcaccgac catttcgggg tcgagtgcag
     7321 atgtaggctc atcaaaaagc atgatgtcag ggttcatcgc tagagcacga gcaatagcca
     7381 cacgctgttt ttgtccacca gaaagcattt caggatacat atctttttta tcttctagac
     7441 caactgtctg cagtaatttg attgcttttt tctctgcttc ttctctagat tctttcttca
     7501 ggtccatcgg tgctaaaatg atgttttcca aaatagaaag atgagggaat aggttaaagt
     7561 gctggaatac cattccgata tgttgtctca ccaagttgat atctgtgctt ttatccatca
     7621 agtgggcgcc gtcaataata atttcaccgt cagaaggttc ttctaaacga ttcaagcaac
     7681 gcaaaaatgt actttttcct gaacctgaag ggccaatgat acagacgaca tctccttcgt
     7741 tgatggatac attgatgtcg tttaatactg tgttatcgcc gtattttttg actaaatgct
     7801 caactaagat tttttctgcc atcttacttc accttctttt ctaaaacttt tgctaatttt
     7861 gtcaatgctg tgatcaaaat caagtacatg atcgcaatga tcaagtaaac atacgtactt
     7921 tgtgttgtac gtgcaacaat gatcttacca gtttgcagca attcgactac accgattgcg
     7981 gaaatgatcg ttgtgtcttt taatgagata acgaactgat tgacgaatga tgggatcatg
     8041 atgcgtattg cttgtggcaa aatgattttt tgcattgtcc gattataaga aagacctaaa
     8101 cttctggaag cttccatttg tccgacagga acggcgttga tcccgcctcg aacaatctct
     8161 gcgatataag cacttgcgtt aagagtcaag gtgataacac cagcaaggaa gtcaggaatc
     8221 gtaaatccaa cgataccagg caacccaaag aaaataaaga acgcaagaac catcattgga
     8281 attcctcgga tgatatcgac ataaatacta gcaattgtgc gaagagcgcg tattggtgct
     8341 acactgaata atccaaaaat cacaccgatt actatagcca aagcaaagga gatcaaagtt
     8401 aggagaattg ttctccaaag tcctttcaac aatgcttgat agttgttttg gataagtcca
     8461 agaaatgttg attcatcagc agtggaagac tcactagaag tttctgaacc atccgctaca
     8521 tattctttga taatcttatc gtattcgcct gttcttttta attctttcaa tccttcattg
     8581 aacatattaa gaagctcagg attttgtcct tttttaacgg caaatgcata ttttccgcca
     8641 gattcttttt cgatcggtgt ttccaattct tgtccttgtt tgatcgcata accgattacc
     8701 ggataatcat ccatcattgc atcgattgcg ccaactttta acccgtcgta caattgatca
     8761 gcagcatcaa aatatttgat agaatagcca tattcagatt catggtcgct taaaaattca
     8821 gcactttcgg taccaacttt tgctccgact gtttttcctt tcaaatcttc ataagacttg
     8881 atcgaagtat ctcctttttt gacagctaat tggatcccgc tatcaaagta agaatcagaa
     8941 aaatcatagc ttttctttcg ttcatctgtt acagtcattc cggcaatcat tccgtctgct
     9001 tgtcctgatt ccaaagcttg caaagcagca gagaaaccac ggtagtccat tcggatgtta
     9061 aatccttgca gtttggcgat gttttccatc aattttacat cgatgccttc gtactcgccc
     9121 tttgcgtttt gaaattcaaa tggagcaaaa gcagagtcac tggcaattac gtatacgtct
     9181 tttttgggct ctattttttg cattgtctcg cttgtgcttg actctgccgt tgtagtgttg
     9241 tcagcttgtg caacatgacc aaacgcaagt gtcacaagtc ctgtcattaa gaaaacaaat
     9301 gagtgaaata aatgctttct tttcataatc aacctcctaa atttccaata ttttattatt
     9361 ataggcgaaa agtgctgaat cagacaagac tgtaagctcg aaaaaatgaa aaaaatgcga
     9421 gtttctaaca ttttatgtta taaaacgtaa catgtataat aagataaaaa agtggcgaaa
     9481 gtatgttcgg tgtggtataa ttttttagta aggaatgcct ttgctttcct tttcttttta
     9541 ttggtcgtaa aatgaaaagg aatgaatgaa aaggaggacg aagaatgatt gagagagata
     9601 cctcccgaca ctttgagctt gtctcgaaat accaaccggc tggtgatcag cctgaagcga
     9661 ttaaccaatt agtggatggc gtagtcggcg ggaaaaaagc acaaatctta ttaggtgcga
     9721 ctggaacagg gaaaacatat acgatttcca atcttattga gaaagtgaat aaaccaacac
     9781 tgattattgc tcataataaa acattggctg gtcagctgta cggggaattc aaggaatttt
     9841 tccctaacaa tgctgttgaa tattttgttt cttattatga ttattatcag cctgaagctt
     9901 atgtgccttc aagcgatacg tatatcgaaa aagattcaag tgtaaatgat gagatcgaca
     9961 aattacgaca ttcggctact agttcattat tagaaagaaa tgatgtgatc gtcattgcat
    10021 ccgtttcatg tatttttgga ttaggttcgc cttttgagta ccaaaaacaa gtagtttcga
    10081 ttcgacaggg agcagaacta gatcgcaatc agttgattcg tgacttagtc agtatccaat
    10141 tcgaaagaaa tgatatagat tttcagcgcg gtcgttttcg agtgcgcggt gatgtcgtgg
    10201 agatttttcc ggcttcaaga gatgaacgtg ccttacgtgt ggagtttttt ggagatgagg
    10261 tcgaacgtat ccgagaagtc aatgcactga caggtgaagt tttaggagaa acggaacacg
    10321 tggcaatctt cccggcgact cactttgtga cgaatgatga acatatggag catgccgtag
    10381 cgaatatcaa agcggaatta gaacagcgtt taactgtctt gcgaaatgaa aacaaacttc
    10441 tggaagctca acgtttagaa cagcgaacca attacgatat tgaaatgatg ttagaaatgg
    10501 gctacacgtc gggaattgaa aattattctc ggcatatgga cggacgtaaa gaaggtgaac
    10561 cgccttatac gctattggat ttctttcctg aagatttttt gatcgtggcg gacgaatcgc
    10621 acgtaaccat gcctcaaatc agaggaatgt ataatggtga ccgagcgaga aaacagatgc
    10681 tagtagatta cggtttccgt ttgccatctg ctttagacaa tcggccactt cggttagaag
    10741 agtttgaaaa acatgtcaat cagatcattt atgtctctgc gacgccagga ccatatgaac
    10801 atgaacaaac agataccgtt atccaacaaa tcatccgtcc gacagggctg cttgacccag
    10861 tgatcgaagt tcgtccaatc atgggacaaa tcgatgatct agtaggcgaa ataaatgaac
    10921 gagtcgaaaa agaccagcgg gtgtttgtaa cgacattgac gaaaaaaatg gcagaagacc
    10981 tcacagatta tttcaaagaa ttagggatca aagtcaaata tttgcatagt gatatcaaaa
    11041 cgctggaacg aacagaaatc attcgagatc ttcgattagg tgaatttgat gtgttagttg
    11101 gaatcaattt gcttcgtgaa ggattagacg tacctgaagt ttcccttgtt gctatcttgg
    11161 atgcggataa agaaggcttt ttacgtagtg aacgttcctt agtccaaacg attggacgag
    11221 ctgctcggaa tgaagaaggt aaagtaatca tgtacgcaga caaagtaaca gattctatgc
    11281 gtctagcgat ggatgaaacg tcaagacgtc gtacgattca gcagaagtac aatgaagaac
    11341 atgggatcgt tccaaaaacg atcattaaag aaatccgaga tttgatttct attacgaaag
    11401 aatcggaaga tgatacaaaa gaagcggtac aagtctcgta cgaagaaatg acgaaggaag
    11461 aaaaagacac gttattgatg aaattagaaa aagaaatgaa agatgcggca aaagctttgg
    11521 attttgaaac agccgcgaat gtgcgagata tgattttaga attaaaagct tcaaagtagg
    11581 aggacaacat ggctaacgat aaaattacga ttcatggtgc acgtgcccat aacttgaaaa
    11641 atatagatgt aacgattcca cgagataaat tcgtggtcgt tacaggtttg tccggttctg
    11701 gaaaaagttc cctagcattt gatacgctgt acgctgaagg gcagcggaga tacgtagaga
    11761 gcctttctgc ttatgctcgt cagtttttag gacaaatgga taagccggac gtagatagca
    11821 tcgacggatt gagtccggcg atttctattg atcagaaaac aacaagtaaa aatcctcggt
    11881 cgacagtagg tactgtgacg gaaatcaatg actatttacg cttgttgttt gcacgtgtag
    11941 gacatccgat ttgtcccaac gatcatatcg agattaccag tcaatcagta gatcaaatgg
    12001 cagatcaagt aatggctttg cctgagcgca caaagatcca agtgttggca ccgatcgtgg
    12061 taaagaaaaa aggacaacat aaaaaaatat tcgaacgaat ccaaaaagag ggatacgtcc
    12121 gcgttcgagt cgatggtgag atctatgatt taagtgaagt gcctgagctg gagaaaaaca
    12181 aaaaacatga tatcgcgatc gtcatcgacc ggatcattgt gaaagaaggg attcgttctc
    12241 gcctatttga ttctttagag gcggccctgc gattagcaga cggctatgct ctggttgacg
    12301 tgatcggtga agaagaaatg ttgtttagcg aacactatgc ctgtccttat tgcggattta
    12361 ctgttggcga actagaacca agactgttct cattcaatgc gccttttgga gcttgtccag
    12421 actgtgatgg tttaggtgtc aaattagaag tcgatcaaga tttagtgatt ccagatagaa
    12481 cgaagacact tagtcaaggt gctatcgttc catggaatcc aatcagctct cagtattatc
    12541 ctcaaatgtt agcgcaggct tgtgaaagtt tcggtatcga tttagataca ccattcgaag
    12601 aattaccgga agagcatcag gagatcatct tgaatgggac agatgatctt ttccatttcc
    12661 attatgaaaa tgattttggt ggcgttcgcg atgtagaaac gactttcgaa ggggtattga
    12721 agaatatcga gcgtcgttat catgatacga acagtgattt cacgcgtgag caaatgcgtc
    12781 tttatatgac agaattaact tgtcagacat gtaaaggtta tcgattgaat ccccaagctc
    12841 tatctgttca aatcaatgga acgaatatcg ggcaaacaaa tgagttgtct attcaaaaag
    12901 cagtagattt cttctcaaac ttaacgttat ctgaacaaga gaaagtaatt gccaaaccga
    12961 ttttaaaaga agtaaatgac agactttcat tcttggaaaa tgtgggacta gactatctaa
    13021 ctttgagtcg cgcttccgga acattatctg ggggagaagc gcagcgaatc agattggcta
    13081 cacaaattgg atcgaatctt tctggagttt tgtatatttt agatgaacca tcgatcggat
    13141 tgcatcaacg cgacaacgat cgactgattg gctcattaaa gaaaatgcgt gatcttggca
    13201 acaccctcgt tgtagtcgaa catgatgaag atacgatgtg ggcagcagat tatttgattg
    13261 acgtcggacc tggggccgga gaacaaggcg gacaaatcgt ggctgcaggc actcctgaag
    13321 aagtagctaa tgatgaaaat tctttgacag ggaaatatct ttcagggaaa aaatcaatcc
    13381 ctgtaccaaa agaacgccgt aaaggtaatg ggaaagcaat caagatcact ggtgcttcag
    13441 aaaacaatct gaaaaatatt agtgttgaat ttccattagg agaatttgta gcagtcacag
    13501 gtgtgtctgg ttctggaaag agtacattgg tcaatagtat cttaaagaaa tcgttagcgc
    13561 aaaaattaaa taagaattct gctaagccag gtaaattcaa gacaatttcc ggctacgaaa
    13621 gtatcgaaaa gatcatcgat atcgatcaaa gcccaatcgg ccggacgccg agaagtaatc
    13681 cagcgactta tacaagtgta tttgatgata tccgtgggtt atttgctcaa acgaacgagg
    13741 caaaaatgcg gggttataag aaagggcgtt ttagtttcaa cgtaaaaggc ggtcgttgtg
    13801 aagcttgtcg cggggatgga attattaaga tcgaaatgca ctttttgcct gatgtctatg
    13861 ttccttgtga agtatgtcat ggtaaacgat ataattctga aacattagaa gtgcattaca
    13921 aaggaaaaag cattgctgat attttggaaa tgacagtaga ggatgctgta gaattcttca
    13981 agcacattcc aaagattcat cgcaaactgc aaacgattgt tgatgttggc ttaggttatg
    14041 tgacgatggg gcaaccagca acgacattgt ccggtggtga ggcacaacgg atgaaacttg
    14101 ccagtgaatt gcacaaaatc tctaatggaa agaatttcta tatactagat gaaccaacga
    14161 caggacttca tagcgatgac atcgcccgct tgttgcatgt attacaaaga ttagtagatg
    14221 ctggtaacac agttttagtg attgaacaca atctagatgt aatcaaaaca gcagattata
    14281 tcattgattt aggaccagaa ggtggagaag gtggaggaac gatccttgcg actggaacac
    14341 cagaagaaat cattaacgta aaagaaagtt atacaggtca ctatttgaaa aaaataatgg
    14401 tataaagagg atagatagct gagatagtta aaaaaacata aaaaaatgaa tttttgcttg
    14461 ttttattaat atcagtgttc tagaatcatt acatggtagt tctttctaca ctgattggta
    14521 tagataaaaa cttcctataa gttcaatccg ttcaaaaaag aattgagcaa tcggaggact
    14581 ttcctttgat tgcttttttc tttatggtat gatattcctt gtgtagttgg aaaagaaaaa
    14641 caagagatta tgagtaagtg agagataatg atgaacagta ttgaaaatga agaatttatc
    14701 cctatattat taggaagcga catgaacgtt tatggtatgg cacgttcttt taatgaagca
    14761 tacggcaaaa tctgccaagc atatgcttcg gatcagttag cccctacccg ctacagtaaa
    14821 attgtcaatg tagaagttat tccaggattt gataaagacc ctgtatttat cgagacgatg
    14881 cttcgtttgg caaaagaaag atattctgat aagagtaaaa aatatctttt gattgcttgt
    14941 ggtgatggat atgcagaatt gatctcccaa cataaacaag agctgtcaga atattttatc
    15001 tgtccatata ttgattattc tttatttgaa aggctgatca ataaagtaag cttttatgaa
    15061 gtttgtgaag aatatgatct tccgtatcct aaaacattga tcgtcagaga agaaatgtta
    15121 gtaaatggac atttggaaca ggaattgcct tttgaattcc cagttgcttt gaaacctgca
    15181 aacagtgtgg agtatctttc tgtccaattt gaaggaagaa aaaaagcttt tattttagag
    15241 actagagaag agttcgattt aattttaggc cggatatacg aagccggtta taaaagtgaa
    15301 atgattgtac aagattttat cccgggtgat gatagtaata tgcgtgtgct aaatgcgtat
    15361 gtagatgaag atcatcaagt tcggatgatg tgccttggtc atccactatt agaagatcct
    15421 acaccagcat cgattggtaa ttacgttgtg atcatgccag attataacga aaaaatctat
    15481 caaaccatta aggcattttt ggaaaaaatc gaatatgcag gctttgccaa tttcgatatg
    15541 aagtatgatc ctagagatgg agaatataaa ttatttgaaa tcaatttgag acaaggtcgt
    15601 agcagtttct ttgtgacatt gaacggcttg aatctggctc gttttgtcac agaagatcga
    15661 gtgttcaaca aaccctttgt tgaaacgacc tatggaacga atcaatcaga taaagcaaga
    15721 ttatggatgg gtgtgcccaa aaaaatcttt ttagaatatg ctcgggaaaa tgaagacaaa
    15781 aaactagctg agcaaatgat caaagaaaat cgttacggta ctactgtatt ttatgaaaaa
    15841 gaccgatcaa tcaagcgctg gttgttgatg aaatatatgt tccataacta tattccaaga
    15901 ttcaaaaagt attttcatgt gaaagaaggc tagttcatgg agaatttttt cagtatttta
    15961 ggcggaatgg gcacgatggc gacagaaagt tttgttcgct tgatcaacca ccgaacgaaa
    16021 gctacaaaag atcaagaata tttgaattat gtcttattca atcatgcaac agttcctgat
    16081 cgtacagctt atattttaga tcgatcagaa gaaaatccaa tgccgtttct gctggatgat
    16141 attgagaaac aaaatttatt gcgaccaaac ttcattgtgt tgacttgtaa caccgcacac
    16201 tacttttttg aagagttaca agcggcaacg gatattccta tcttgcatat gccaagagaa
    16261 gcagcaaatg aacttgtccg tcagcatacg acagggagag tagcgattct aggaacagaa
    16321 ggaagtatga aagctggaat ctatgaacgc gaagtcaaaa atcttggttt cgaaacagtg
    16381 attcctgata ctgcgcttca agaaaaaatc aattacctga tctatcatga gatcaaggaa
    16441 tcggattatt tgaatcaaga gctctattac gaaatcttag aggaagcggt agagcgccta
    16501 aactgtgaaa aagtcatcct aggttgcaca gaattatctt tgatgcatga atttgctgaa
    16561 gataatcatt acccagtgat cgatgctcaa tctattttag cggatcgaac gatcgaacgt
    16621 gcattagctg aaagaagcga ggcattggat acagcatcgg aaaagtaaaa aaattggatt
    16681 tggggcaaat atcctaaaag
//
LOCUS       DASHWW010000063        15949 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.063, whole genome shotgun sequence.
ACCESSION   DASHWW010000063 DASHWW010000000
VERSION     DASHWW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.063"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            31..1062
                     /locus_tag="U2R64_002199"
     CDS             31..1062
                     /locus_tag="U2R64_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEM8918991.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            1059..1826
                     /locus_tag="U2R64_002200"
     CDS             1059..1826
                     /locus_tag="U2R64_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEM8918992.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            1926..3494
                     /gene="liaX"
                     /locus_tag="U2R64_002201"
     CDS             1926..3494
                     /gene="liaX"
                     /locus_tag="U2R64_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HEM8918993.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            3784..4110
                     /locus_tag="U2R64_002202"
     CDS             3784..4110
                     /locus_tag="U2R64_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEM8918994.1"
                     /translation="MRHDEKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSL
                     VAFGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDD
                     DEWSDF"
     gene            4110..4460
                     /locus_tag="U2R64_002203"
     CDS             4110..4460
                     /locus_tag="U2R64_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEM8918995.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            4627..5565
                     /locus_tag="U2R64_002204"
     CDS             4627..5565
                     /locus_tag="U2R64_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEM8918996.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            5580..6410
                     /locus_tag="U2R64_002205"
     CDS             5580..6410
                     /locus_tag="U2R64_002205"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEM8918997.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            6454..7479
                     /locus_tag="U2R64_002206"
     CDS             6454..7479
                     /locus_tag="U2R64_002206"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEM8918998.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            7494..8432
                     /gene="galU"
                     /locus_tag="U2R64_002207"
     CDS             7494..8432
                     /gene="galU"
                     /locus_tag="U2R64_002207"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEM8918999.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            8557..8997
                     /locus_tag="U2R64_002208"
     CDS             8557..8997
                     /locus_tag="U2R64_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEM8919000.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            9000..9602
                     /locus_tag="U2R64_002209"
     CDS             9000..9602
                     /locus_tag="U2R64_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEM8919001.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(9661..10767)
                     /locus_tag="U2R64_002210"
     CDS             complement(9661..10767)
                     /locus_tag="U2R64_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEM8919002.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            10977..11978
                     /gene="ccpA"
                     /locus_tag="U2R64_002211"
     CDS             10977..11978
                     /gene="ccpA"
                     /locus_tag="U2R64_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEM8919003.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(12315..14660)
                     /locus_tag="U2R64_002212"
     CDS             complement(12315..14660)
                     /locus_tag="U2R64_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEM8919004.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            14939..15841
                     /locus_tag="U2R64_002213"
     CDS             14939..15841
                     /locus_tag="U2R64_002213"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HEM8919005.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
BASE COUNT         5118 a         2823 c         3327 g         4681 t
ORIGIN      
        1 cttttcatca tttcatagaa aggataaaga atgcaaaaaa aaattagcat catcactata
       61 ttttttattt gtgtgcttac ttcatgggtt attcagcatc aagccgcttt atatgaagta
      121 cctgtcatcg agatagaaaa agtacgaata aaagaggatc atcaattgat tacaggaaaa
      181 ctgatgaaca cggatcaaaa aggagaatcg atttatttat cggttcctta tcaaaaaaat
      241 caaatagaaa cagcaaatat aaaagcgaga caaatgtatc tagtccaaat gcatggagat
      301 gaatggcagc tagtagcaaa aaaaaatgat ggctggcttt tcttcttcac aagtatcttc
      361 attggcgcca tgttgcttat tggtggaaaa cagggtctat ttgctttagg aagtctcatc
      421 atcaatatcg ttttactttt acttttgttg ctcatcttta ctaaaacaga agggatttct
      481 ctattaaata tatctatcct gttcgtcgtt atagggatga ttattagcat attggcttta
      541 gatggatgga atagaagcag tataatcaaa atttcagctg cagttacgag tgttttttta
      601 gcatttttta tttgtctttt gacaatgaat cattggaaag accaaggact gcgctatgag
      661 gaactgaatt atctgacacg accgtatcgt tctgtttttc tttctagcgt actgattgga
      721 acagctggag gaacactcga taccgttatc acagtcattg cgacattaga agaattgact
      781 aagcgacaac cagaaataac agcgaaacag ttatggcttt caggaaggca agtgggtcga
      841 gatgtgattg gctcgatgac caatatcctt ttgttcgtct atatcagtgg gtcagttcca
      901 tcgcttcttt tatatttagg aaatcaatgg tcgttcaaag aaacgataga acagcattta
      961 tcattggaat ttttacgcgt cattgctggc agcttaggaa tagtattatc gatccctatc
     1021 tcggtcctct tttttctgac tgtaaggagg ctgaaacgat gaatgtactt attatacttg
     1081 ttgggatttt agcaatcagc gtgctactta ttggcggtac gcaaggtatg tatattcttt
     1141 taggcttatt catcaattta gggatctttt tcctgttgtt attcggttat catcagaagt
     1201 ggccgatact ggcattgtcg gtcataggat ttttattgat tgctgtggtt atcttatttt
     1261 ttatcaacgg ttataatcta aaaatgcgtg cagcttttgt gagtatactg atctttttat
     1321 tttgtttcct actattgctt cctatcactg attttttagc aatccaaggt tttacatcgg
     1381 tagaactaga agaattatct ggcttagata agactttagc gattgatttt agattactta
     1441 cgagatcgtt gcttctgatt agtcttagtg gtgctgtttt agatgcgagt gtagcaattt
     1501 ctagtgggac attcgaagta tatcaggcaa atccgcaatt atctttttac caattgcgcc
     1561 attctagttt cgctattgct aaaaaaatat tggcgtcaac agtaatgaca cttctttttg
     1621 cattcatggg aagttcttta gcgttgatcc tctggtttat tgatttagac attccttttc
     1681 agcaagtgat caatgaaaaa tcatttgttc tagaatatac gatggctatt cttaccacat
     1741 tgtccgcact acttgttctt cctttaacct gcgtgactac agcatatctc tttacaaaaa
     1801 agaaagaaca actcaagatg gagtaaaagt tacaacttaa gtcctatgac atttttactg
     1861 aatcagtgca taatatggat gtaaggaaaa gcttgcaaac aattttgctt aaggaggcaa
     1921 tttccatgaa agaaagagaa cgtattttag atttagtgaa aaaaggaatc ctttcgactg
     1981 aagaaggctt agatttatta gaaagcatgg caactgaaaa agacgaaaag caaatcaaaa
     2041 aagaagcaga caaggtaact gctagtcata aagaaaaaga tcaggcaagt caattgatcg
     2101 ataaacttga aaacggcgaa gaagaaattt ctgagccagt tgatccaaag gaaagagaaa
     2161 gacaagatca agaaaactta gaaaagatct tagatgaact agcaactgaa gcgaataaaa
     2221 cttcggcgcg tctagatgaa gtaaatgctc aattcgctga caataaggca gcacgcaatg
     2281 agaaacagga agcattgatg cagctgaata caaaagaaga attaggcgag ttgacagaag
     2341 aagaattagc acagcgtcag acgttagaag cagaaatcaa agaattagaa gctagtggcg
     2401 atacactgtt agaagaacaa ttgaaattag aagcagaatt aaaagatatc cgtaagaatc
     2461 aatggtctga gaaaaaagaa acgtttactg ataagtttga attgccagat gattggaaag
     2521 atcaagcaac agatacactg aatcaagtag gcgaaaaaat gtcagaagct ggatcacagt
     2581 taggcaaatt cttgaagaaa acattccaaa ctgtttcaga aacagtgaat gacaacatgg
     2641 aatggaaaga tgtcagctta cgtgtccctg ggattgcgac aacgaaattt gagcatgaat
     2701 tttactatga agctcctgca gcaagtatcc ttgatatcaa ggcagcaaac ggaaacgtga
     2761 cgttaaaaac gtgggacagc aacgatgtga aagttgaagc taagatcaaa ctttacggaa
     2821 aaatgggtgc tgaaccattt gaagcattct ctgaacggag ccagattgag gttaatgaag
     2881 atcatatctc cttccaaatt ccaaataaac gtgtgcgtgc agaccttgtt ttctacttac
     2941 ctaaacgagt atacgaccac gcagctatta aacttctaaa tggcaacatc atgattgaaa
     3001 cattggaagc taaagatatt tatacaaaat ctacgaatgg taacatcatc gtggaccaat
     3061 taactgcaac gatgctggaa gtagaaggtg taaacggcaa tatcgatatt cgaaacggga
     3121 acatcttaga ttctattatc gaaacagtaa atggtacagt gacatttggt gcgacagcag
     3181 aaaacctttc tgtgtctttg gtaaatggtg atgtacgtct tacgattaaa gaagataatt
     3241 tgaaaaaagt agaagcaagt tcagtgaacg gaaatgtcaa agtcgcttta ccagatggca
     3301 tcggtttgga aggacatgct aaaacaagtc ttggaagtat caacagccgt ctgtccaatt
     3361 acgaagtagt tcgtgagaaa aaagaacgga caaaccaaat gttgcaattc cgtcgtgttt
     3421 cagatggtga aatcgcgcaa gtgcaacttt caacgacaac aggaagtatc tatttaaaag
     3481 atacagataa ataaagaggt tgtgaaagag atgttcagcc ttgagcaata agaagcgatt
     3541 ttgtaaaata gcttccccta ttttacaaaa ttgtgcctta ttgccgatag tctatctctt
     3601 gaacaccgtt taccaagaga ttatgaacct gccaattatc gccgagtcac aaggaataat
     3661 ttcagaaaaa gctcgtcacg ttttatgaat atggtaattt gtgaccgaga attttgcaga
     3721 aagacaccga ttaagaagaa ggttgtcaca acgattttct tcatttaaaa tagtagaaca
     3781 gaggtgagac atgatgaaaa aaagttgaca aaatctaata aaaatgttgt tttgacaggg
     3841 actttagcag gaataggaga atacatcggg attgatccga ctgttatccg tgtgctttat
     3901 gtattcctga gcttagttgc ttttggaagt ccaattattt tatacatttt attagctttg
     3961 attatcccat ctgcgcgttc tgcacgaaca aactatggac ataacaatgc atattatgaa
     4021 aaaaacaatt atcgtgaaca aactcgtgaa caaacaaaaa aacgcaaaga agcggaaaaa
     4081 atcgatgatg acgaatggag tgacttttaa tgtcgtactt tcaacgtatt ttagttaata
     4141 cgttaacatt catatcattg gctgttcttt ttcctgcgat ggtccatgtg agcagtattt
     4201 ggacggccgt tcttgccagc ttcgtattgt ctgtgttgaa tatgtttgtc aaaccgattt
     4261 tgacgatact gtccctgccc tttacattag tcacattggg attgtttacg tttgttatca
     4321 atgcagcgat tcttaaaatg acctcctttt ttgtgggagc agaacatttt agtttttctt
     4381 cattcggtgc agcgttgtta gtagctatct tgatgtcgct tgtcaatgta attgtcagcg
     4441 aacataacag tagaaaataa aagaaagctg tgccgaacta tcggcgcagt ttttttattt
     4501 agaatcagga atgcgttttc tattacattg gtaattaaat aaaaacgttt tttttaattg
     4561 gtagtacttt tggctagaca atgataaaat gatagagaac actctaatag aaatgaggta
     4621 gcatgaatgt cagaagttgt aaaagttagc caattagtga aaaaattatc tttggaaatc
     4681 gtgacaggcg acgagaaaag cttagaccgt gtcatcgtaa ctggggacat ctcacgccca
     4741 ggactagagt tgactggtta ttttaattat tattcccata atcgtttaca gctatttggc
     4801 agtaaagaaa tcagttttgc ggaacggatg atcccagaag agcgtttgat catcatgaga
     4861 agattatgta gtgaagatat gcccgcattt attatttcaa gaggattacc agctccagaa
     4921 gaaatgatcc aggcagcaaa tgaaaatggg atagctgtac tgcgttctcc catctcaact
     4981 tctcgtttat taggagaatt atccagttat ttagatggtc gccttgcccc tcgaacaagt
     5041 gtccacggtg ttttagtgga tgtttacgga ttaggtgtac tgattcaagg tgacagtggg
     5101 ataggaaaaa gtgaaacagc gttggagttg atcaaacgcg gccatcgatt gatcgcagac
     5161 gatcgagtag atgtttatca gcaagatgaa ttaacggtga tcggagaacc gcctaaaatc
     5221 ctggaacatc tgattgaaat ccgaggaatc gggatcattg atgtaatgaa tctttttggt
     5281 gcgagtgcgg tacgtggctc tatgcaagtc cagttggctg tttatctgga agcatgggca
     5341 aaagataaga aatacgaccg tctgggctct gaagacacga ccgttgaaat cgcggaagtg
     5401 ggcattccac aaataaaaat ccctgtcaaa acaggacgaa acgttgcaat catcattgaa
     5461 gtagccgcga tgaatttccg tgcacgtaca atgggctttg acgcaacgaa aacatttgaa
     5521 gaaagattaa gtcgcttgat tgaagaaaac tcaggcaacg actagcaagg agtgacaata
     5581 tgttagcaca aatcaatcga gttgcttttg agcttgtagg gattcctatc tactggtatg
     5641 cattgatcat cgtatcaggt atcattatcg ctatgtggct tagcagcaga gaggctgttc
     5701 gggtaggatt aaaagcagat gatgtgacag attttatgtt gtggggattg cctatctcca
     5761 ttattggcgc tcgcttatat tatgttttat ttgatcttcc ccagtatata gctgatccaa
     5821 tccaaatatt caatatccgt tcaggaggct tagctattta tggcggactg attgcaggcg
     5881 cgatcacgct gtattttttt actaaatatc attttatttc tttgtggact tttttagata
     5941 tcgctgcacc aagtgtatta ttagcacagg caatcggtcg ttggggaaat ttcatgaacc
     6001 acgaagcata tggaccagac acgacgcgaa gcttcttaga aagtctgcat ttaccgcaat
     6061 tcatcattga taatatgtat atcgaaggga tctatcgtca accaacattt ctttatgaat
     6121 cactttggag tttgattgga tttattttgc ttttgttttt acgaaagaaa ccacaccttt
     6181 tgaaaaaagg cgaagtcctt ttatgttatc taatgtggta tagtttcggg cgtttcttta
     6241 ttgaaggatt acgtacagac agtctttact ttttaggtgt gatccgtatt tctcaattat
     6301 tatctgctgt gttatttgtc ggtacattga ttctatttat ttggcgcaga aaaaaaggaa
     6361 atttaccgga ttatgaccgc tcattaggaa aaaatcaaca aattatctga tttttagagc
     6421 gttaaaaatg aaaaaaattt caggagtggt aaaatgaatt atagagtagc ggttttagga
     6481 ccaggctctt ggggtactgc tttggcacaa gtcctcgccg aaaacggaca tgacgttcgg
     6541 atttggggac atcgtgcttc acaagtagaa gaaatcaaca cccaacacac gaatcaacgt
     6601 tatttaccag atcattatct acccgattcc atccaagcat tcaccaatat ggaagatgca
     6661 gtaaaagacg cagatgcggt gctattcgtc attccaacga aagcaatacg ttctgttgca
     6721 aaagaactag tgcctaaatt gaatacaaag ccagtgatca tccatgcaag taaaggatta
     6781 gaacagggaa cacataaaag gatctctgac atcttgttag aggaaatccc agcagaaaaa
     6841 agaaaagctg ttgttgttct ttctggacca agccatgcag aagaagtagc aaaacatgac
     6901 atcactacga tcacagctgc aagtacagat gcaaaagcag caaaatatgt acaagagctg
     6961 ttcatgaata attattttcg gatctatacc aatcctgatg tgatcggtgt agagatgggg
     7021 gcagctttga aaaatattat tgctattggt gctggcgcta ttcacggctt agggtttggc
     7081 gataatgcaa aggcagcaat catgacgcgc ggattagctg agatcagccg tttaggtgta
     7141 gcaatgggtg ccaacccgct gacctttatc ggattaagcg gaataggcga tctagtcgtt
     7201 acttgcacaa gtgttcattc taggaactgg cgcgcaggca acttgttagg acaagggcag
     7261 cccctagaag aggtgctagc caatatggga atggtcgttg aaggtgtgaa tactacccaa
     7321 gcagcgatgg aactagccca aatgatggaa atcgaaatgc ccatcactca aacaatctat
     7381 gaagtgctgt atgaacaaaa agaaatcaaa acagccgcaa aagaaatcat gttacgtgat
     7441 ggaaaaaaag aaaatgaatt ctcattaaca attttttgaa ggagcgaatg tatatgaaag
     7501 ttaaaaaagc agttattcca gcagcaggat taggaacaag atttttacca gcaacaaaag
     7561 ctatggcaaa ggaaatgttg ccaattgttg ataaaccaac aatccagttc atcgttgaag
     7621 aagcgttgaa atcaggtatc gaagacatct tgatcgttac aggaaaagct aaacgaccaa
     7681 tcgaagatca ctttgattca aatattgaat tagaaacaaa cctaagtgaa aaaggaaaga
     7741 ccgaattatt gaaattagta gaagaaacga cagatgtcaa cttgcatttc atccgtcaat
     7801 ctcatccaaa gggtttagga catgccgttc ttcaagcaag agcctttatt ggaaatgaac
     7861 catttgtcgt tatgctaggc gatgatataa tggaagacga agtaccattg acacagcaat
     7921 taatcgatga ttacgaacgt actcatgctt ctacgattgc cgttatgcaa gttcctcatg
     7981 atgaaacttc aaaatacgga attatcaatc caggagaagt attggaagat gggttataca
     8041 atgtcaaaaa ctttgttgaa aaaccagatc caagcaaagc accaagtgat ttagctatta
     8101 ttggacgtta cttattgact ccagaaattt ttgatgtatt gtccgagcaa caaccaggag
     8161 ccggaaatga aatccaacta actgacgcaa tcgatacatt gaataaaaca caacgcgtat
     8221 ttgcccgtaa attcacaggt aaacgttacg atgtcggtga caaatttggt tttatgaaaa
     8281 caagtattga atatggtcta acacatccag aagtaggtgc acctttacgt gagtacatcc
     8341 tgtctttagg taaaacatta gaagcagaag gaagcaagat cgatcataat ccaaaaggaa
     8401 taacagaaat caaagaagaa aagaaaaaat aacccttttt tctaacgagc ttcagctgct
     8461 aattgaataa aaagtagttg aagctcgttt ttatttgttt aaaaaacacg aaaatgctat
     8521 ccttatagaa aagagagaca agaagggagt ttgatcatgt caggaggaga aattgcagga
     8581 ttgatcgcag caatcgcctt tgcgatactt gtcgttttta tcgttcgtgt gttgttgcaa
     8641 gtttctaaaa ctttagaaaa agtagatcag actgtagcag aagcaaatac gacgatcgaa
     8701 atcgtcacaa aagacgtaga tcttttgtct agacaagtag aaggcttact ggtcaaaagt
     8761 aatgaactgc tcttggatat caatggaaaa gtcgcaacga tcgatccatt gttcacagca
     8821 gttgctgatt taagtgaaag tgtatcagaa cttaatcatt ctagtaaaaa catcgcgacg
     8881 aaagtcggcg gaatcggtaa aacgacagct aaagcgacgg ttgccggaaa agtcggtggg
     8941 acagcgatga aattttttaa aaacaaaaaa catactgaaa cgacaggagg aaaataaaaa
     9001 tggctaaaaa aggtggattt ttattaggtg cagtagtcgg aggcacagcc gcagcaatcg
     9061 ccgcgttatt gttagcacca aaatctggta aagaacttcg ggatgaatta gctgcccaag
     9121 cggatgattt gatggatatg gcttcagatt acacagatat ggcgaaagaa aaatcgactg
     9181 agttaacagg tattgcaaaa gaaaaagcgc aagatctttc tcaacaagca ggtgatctag
     9241 caggtagtgt caaacaaaaa gtaagtgaat cagcagatga agcaggaagt gaatctgacg
     9301 atatcttgtt aaatcttaaa gaacaatcag ctgacttatc taatcgtttc aaaaaaacgg
     9361 cagaagatat gaaaaaacct gcagatgaat taggaagtat tgctaaagat acttcagaag
     9421 atatcatgat tgatgtaaaa gacgctgctg gtaaagcagg agatactgtc aatgaaggaa
     9481 tgtcagaagc aaaaccagtt gcagatgact caaaagaaat gatgaaaatg gcaaaagaag
     9541 atgcgaaaga agctaaaaaa gaaataaaag atacaatgac agattcatct acaaatcact
     9601 aaaatcacaa atttatagaa taaaaaggtg ggagcggact agctctcacc ttttttactc
     9661 ttatttttct aaaacaagta attcttttgg tgtagtcgtg aatggcacac agccatcgct
     9721 tgtcacatat acacagtctt cgatacgtac ccctactttt tcaggaatat agattcctgg
     9781 ttcaagagag aagcacatcc cttcttcgat tactaagtca tttccttcta caagggaagg
     9841 gaattcgtgg acggttgttc cgatcccgtg acctaaacgg tgattgaaat attcgccgta
     9901 gccatagctg ttgatcacgt ttcgtgcgat ttgatcaagt tcacctgctg tcacacctgg
     9961 acggacggct tcttgtgcgg caagctgtgc ttcaagagtg atgttgtaga ttttttcttg
    10021 gaagtcggtt ggtttttgat aagcaattgt acgagtagca tcactgcaat agccattcca
    10081 aacaacgcca agatcgaata acacaagttc attcggtgaa atcttcgtat ttcctggtgt
    10141 accatgaggg cttgcagcat ttgctcctgc aaggactaat gtgtcgaaag acatttgtga
    10201 aacaccttgt tttttcaatt ggtattcaat ttctgcaatg atcgcttgtt cagtcacgcc
    10261 ttctttcact gctttaaagc caatctcaaa tgcaacatcg gcccatttac cagcttcgat
    10321 cagtttgtct ttttcctcta gagttttgat cagttgtaga cgttggatga tggaagttag
    10381 atcagtgtaa gaatccgttc ccgtcaagat atcagagata gcatcgaagc gctcgacagt
    10441 caaggcgttc ttttcaatcc ctacattgcc aggctgacca tagcgagcac gaagttcttt
    10501 tccgatgatc tcccaagggt tttcgctgtc taaatagcca cggacatcat acgcccaact
    10561 actgttttga gcatcttcaa cttccaaagc aggagtgaaa aggaaaggat cttgttcaag
    10621 agggataaaa agagctagta cacgctcatg aggatcactt tcgtatccgg aaaagtaagc
    10681 gatgtggcca gggtcgctga tataagccaa ttcgacttgg tgttgtgcca tccattgacg
    10741 tagttcattg atttttacgt tattcatttg gcaacctact ttctaaatta attttgtatt
    10801 caataattgt accactgatt tattaaaaga ccaacgttct aaaaactgaa aaaagtaaaa
    10861 attttcatga aaacagagat aaaacggttg caattcttga gattatttga tattctattt
    10921 tagaaatgta agacgtattt tcagaaaaca tataaaatat gaataggaga acacaaatgg
    10981 aaaagcaaac aatcactatc tatgatgtag cgagagaggc aaatgtttcg atggctactg
    11041 tttcacgtgt cgtaaatggc aatccaaacg ttaaaccagc aacaagaaaa aaagtcttgg
    11101 aagttatcga tcgcttggat tatcgtccaa acgcagttgc gcgtggcttg gcaagtaaga
    11161 aaacaacaac agttggtgta atcatccctg atgtcagcaa tatgttcttt gcttctttag
    11221 cacgtggtat cgatgatgtg gcaacaatgt acaaatacaa tattatctta gcaaattcag
    11281 atggcaacga ccaaaaagaa gtcaatgtat tgaataactt actggctaag caagtggacg
    11341 gcgtgatctt catgggtcac catatcacag acgaaatccg tggagaattt tcacgttcaa
    11401 aaactcctgt tgtattagct ggctctattg atccagatga acaagtaggt agcgtaaaca
    11461 ttgattatgt atccgcaaca aaagatgcag taaacaaatt ggcaaaaagc ggcaataaaa
    11521 aaatcgcttt tgtcagtggt gcgttgatcg atcccatcaa tggacaaaat cgtctgaaag
    11581 gctataaaga agcattaagc gaaaataacc taccatatag cgaaggattg atctttgaag
    11641 cacaatacaa cttcaaagat ggtctatctc tagtcgatcg gatccataat agcggtgcaa
    11701 cagctgtcta tgtttcagat gatgaattag ccatcggtat tttggatggt ttattagacc
    11761 gtggcgtgaa agtaccggaa gaattcgaaa tcatcacaag taacaattca ctactgacag
    11821 aagtagctcg tcctcgttta acaagtatca cacaaccatt atacgattta ggggcggtat
    11881 ctatgcgcct attgacgaaa atgatgaata aagaagaagt cgaagaaaaa acgattatct
    11941 tgccttatgg aatcgaagaa aaaggatcta caaaataata aaaggacaac cattcagagg
    12001 ttgtgtgcct gccgtttaac tctgcgttac aaggagcaat ttcaaaaaac agcatctcat
    12061 gtttgatgaa tattgtgact cgtgattcgg agttggcagg agaacaccgt ttatttggga
    12121 aaaggggtta tgacaaaatt ttgttataat cctttttttg tgtcttaaaa aagagagaaa
    12181 gtggttgaaa ttacatttat cgtatataaa acaatccgtg tatagatgct gcattttgtt
    12241 caccaccatc aaaaaaataa gggactgtga caatactatt gtcacaatcc cttattactg
    12301 tgtattctat taaatcaatc atctttctca tctgattctt tagttgcttg attcgctctt
    12361 gcataagctg aagcggtgtt ccagtaatct gtatagtttt catcggtacc gccaacgcca
    12421 aatttaaagg cgcttttctt cggtccattt ttcgcccata gcgattcaac tgtttttcct
    12481 ggtgtttgga tggatttttt attgacagta acttttccag gtgtttgacc agtaaatcca
    12541 gatacttttt tcttcatcac atcagatgat aattcgaatt tctcatcagt gccaaaaatg
    12601 tcaggttttg cttggtaagc ttgattgatc agattggcaa gataattagc cgaacgtatc
    12661 cttgctttgc tgtccattcc agtattgtca tcgtgccctg cccagctact gatggtaata
    12721 gacggagtag agacaattag ccatgaatct cggtattcat tggtagaacc agtttttccg
    12781 acccaatctg cttttcctag atttccgttt aagcttgaga tggcatcttt gaatggtgta
    12841 gtgatttttg cattgatcac actacgcatc atgtcattca tgatcgatgc cgttgcttcc
    12901 gaatagatcc ggacagagtt gctttcgtgt ttataaatta catttcctgc gttatctgtg
    12961 atggaatcga tgatatagcc ttcttcatag acgccgccgt ttgctaaagc ctgaaatccg
    13021 ttggtctgtt gaagcgtcgt gacatctact gtacctaaag gagcagattc aacgccccaa
    13081 ttgtcatttg ccgggtagtt catctttgcc aagtagtgct cgtaagcata ttgtttcgat
    13141 ccaccggaat tcaacacatc ttgatataag tgataagccg ggatattgtt ggaccattct
    13201 agtgactcac ggacggtttg gaaggtgttc gatccttcgt tagtagcatt gacgattttc
    13261 tcgccagcat tttctccttc ttgccaagtt gttgcataat ctgatacacg ggattctgat
    13321 ccgataagcc ccatgtcgat tgcaggtcca taaacaagaa ctggtttgat tgatgagcca
    13381 gcttgacgtt ctgtatcgaa ggcatggtta ttttgattct gactgtaatt ccgtccgcca
    13441 acgaatccgt agatgcggcc agttctgtta tccatcaata catttccggt ttctacttga
    13501 ctgccagcac catcatctaa catgtatcca taattttcaa cgccattttg caatgcagca
    13561 tagacatctt tatcgattgt cgaatggatt gtatatcctt tattttggat cgtttgctgt
    13621 gccttttgat aataagcgtc actgaccgat gaatcagaca tatcagcgtt gtctttttca
    13681 gccaattgtt gtgcaatgat tcttgttgct tcattcatca cagtataata caagaattct
    13741 ctgtcagtct gttctgcgat ttgttgtggt agaaagtctt ttgtaaggtc ataggctttt
    13801 gcttcttcgt attgttcttt cgtaatttgg ccttcacgat acatactgaa taaaacaaaa
    13861 tcttttctgg caaggccggc agaaagatct tcttttagcg cgcctgtgtt cgtgtatgga
    13921 ctatacgtga tcgggctttg gggtaatcca gcgatataag cagcttgcgg cagcgtcaca
    13981 tcttttgcat ctacaccaaa gattcctttt gcagcttcct ggactccagc aatgttttgt
    14041 cccttattat tacgaccaaa tggtgagaca ttcaaatacg tagcaatgat ctcatctttt
    14101 gaaaagtatt tttctacttg tgcagaaaga atgatctcgt ttgctttacg tttgaatgtt
    14161 gtttcatctg taaggatctg ctgtttgact aattgctgtg tcaaagttga tccaccagaa
    14221 gagccaatac cagtagcttc agatactaat gctcgtaaaa cagctttagg aacgtaacct
    14281 tggtgtttat cgaagtattc atcctctgtg ctgataattg cagttttcaa taaaggtgaa
    14341 atcttatcag atgaaatagt cgtgcgcatc agatctgtct ggatttttga tatctctgta
    14401 ttatctgcat aaacaatctt tgacgtttct gtaatgtttc ctagttctgt ctgcagtgct
    14461 tttttagtcg gcaattgtgt gtcttcgacg agataggcaa aatagccagc gcctattcca
    14521 atacctagag ctgcgaacat caaaagaaga acagtaataa aaacagtcaa tgattgaaaa
    14581 actctaaaaa taatcttagg aacaaaccat ttttcttttt ttcttctatt ctgttttttt
    14641 cgagtatttt tgcgtggcaa aagggtcacc tcaactaatg gttttatttc gctaattata
    14701 gcaaataata gaacaaaaaa acagacaagg ctgtttttgg caggaatttc ttttttaaaa
    14761 gagttaaaac gtgagaaaat gatctttatt ataaaagagt tcttaagctt ttctttagag
    14821 aaaatttcag ttactatgga gaacagggca aagaaaaatc aatcattttc tttgtatatc
    14881 atcttaccaa tatataggaa ttgttagtaa caattgcctt tcaaggagga atccatccat
    14941 gttattaggc tcacacgtca gcatgagcgg aaagaaaatg ctgttaggag cagcagaaga
    15001 agcagccagt tatggatctt cgacttttat gatctataca ggcgcccctc aaaacactag
    15061 aagaaaagcc atcgaagaga tgaatattga tgccggaaaa gcgtacatgg cagaaaaagg
    15121 tctaacaaat atcgtcgttc atgcccctta tatcattaat ttggggaata cgatcaaacc
    15181 agaaatgttt ccttttgccg tccaatttct gagagaagag attgttcgtg cggaagcttt
    15241 aggcgctact caaattacac ttcacccagg tgctcatgta ggggcaggaa cagaagccgg
    15301 aattgctaga attattgaag gcttgaatga agttttgaca aaagaacaga cggcacaaat
    15361 cgctttggag acaatggcag gtaaaggtac ggaaatcggt cgaacatttg aggaattagc
    15421 gcaaatcatc gatggagtaa aattgaatga aaaattatcc gttacttttg acacctgtca
    15481 tacgaatgat gccggttata atattaaaga agacttttca ggtgtaatgg aagagtttga
    15541 taagatcatc gggttagatc ggcttaaagt actccatatc aatgattcta aaaatccgca
    15601 aggttcgcat aaagaccggc acgccaatat tggttttgga acaatcggat tcgacacgct
    15661 gaataagatc gtccatgatc caatgtttga caatatttcg aaaatcttgg aaactcccta
    15721 tgtaggcaaa gataaaaaga aagcttacgc accatatgga aaagaaatcg ccatgttcaa
    15781 agcgcaaaca ttcgatccag aagtgtttcc tgagttatta gcagaagaag tgatactcta
    15841 agattttcta tctgacagca gcaaaaaagg accaggcaca ttgccttgtc cttttttgtt
    15901 taagaaacaa aggagtactt tttgcagtct ttttcatcat gcatcttct
//
LOCUS       DASHWW010000064        15471 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.064, whole genome shotgun sequence.
ACCESSION   DASHWW010000064 DASHWW010000000
VERSION     DASHWW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.064"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1126)
                     /locus_tag="U2R64_002214"
     CDS             complement(<1..1126)
                     /locus_tag="U2R64_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEM8919006.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRD"
     gene            complement(1209..1544)
                     /locus_tag="U2R64_002215"
     CDS             complement(1209..1544)
                     /locus_tag="U2R64_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HEM8919007.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(1554..1928)
                     /locus_tag="U2R64_002216"
     CDS             complement(1554..1928)
                     /locus_tag="U2R64_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8919008.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(1941..2255)
                     /locus_tag="U2R64_002217"
     CDS             complement(1941..2255)
                     /locus_tag="U2R64_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8919009.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="U2R64_002218"
     CDS             complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="U2R64_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEM8919010.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(6009..7175)
                     /locus_tag="U2R64_002219"
     CDS             complement(6009..7175)
                     /locus_tag="U2R64_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8919011.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            7200..7526
                     /locus_tag="U2R64_002220"
     CDS             7200..7526
                     /locus_tag="U2R64_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919012.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            7679..8731
                     /locus_tag="U2R64_002221"
     CDS             7679..8731
                     /locus_tag="U2R64_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEM8919013.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            8807..9025
                     /locus_tag="U2R64_002222"
     CDS             8807..9025
                     /locus_tag="U2R64_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919014.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            9012..11585
                     /locus_tag="U2R64_002223"
     CDS             9012..11585
                     /locus_tag="U2R64_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919015.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            11576..11773
                     /locus_tag="U2R64_002224"
     CDS             11576..11773
                     /locus_tag="U2R64_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919016.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            11777..12388
                     /gene="mobC"
                     /locus_tag="U2R64_002225"
     CDS             11777..12388
                     /gene="mobC"
                     /locus_tag="U2R64_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEM8919017.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            12373..13764
                     /locus_tag="U2R64_002226"
     CDS             12373..13764
                     /locus_tag="U2R64_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEM8919018.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            13980..14294
                     /locus_tag="U2R64_002227"
     CDS             13980..14294
                     /locus_tag="U2R64_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919019.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            14287..14781
                     /locus_tag="U2R64_002228"
     CDS             14287..14781
                     /locus_tag="U2R64_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919020.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            14849..15163
                     /locus_tag="U2R64_002229"
     CDS             14849..15163
                     /locus_tag="U2R64_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919021.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            15262..>15471
                     /locus_tag="U2R64_002230"
     CDS             15262..>15471
                     /locus_tag="U2R64_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEM8919022.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         5204 a         2602 c         2782 g         4883 t
ORIGIN      
        1 gatcgcggat tccgtctcct aaatatttcg catccggcct ttggcaagcc aaaatcagaa
       61 agaaaccaga ttgacgaccc aacatcacga tttgtttgag cttattcaaa atcaccgcac
      121 tttctttcgt cgttaacatc tccatataag ccacgtattc atcaaagatt aaaaagttgg
      181 gtggaagtcc aagataggca taattctctc ctgttttgta gttagacatt tctttcattg
      241 ccttgctacg agccatcata cgttcataga aatcttccac acaagcagaa atttcttcct
      301 tttgtgaata aacatgaggc atcaccgtac ctaaatcagc taaatctgca tttttgggat
      361 cgaggataaa caattctgca tctgacttca atagtgcttc gataatggtg aggaggaaat
      421 aggtcttccc tccacccgtg ccaccagcga ttaacatatg gggtaaagaa tcataagccc
      481 atacttgatt tttcatcaat cgcagagtcc cattttctgc cactacttcg tctatcccaa
      541 ttcgattggc gatcatatca tacagtaaag tatactccac ataggagtct ttgagttcct
      601 tttctactaa ctcacaatac agtccgcttt ctaacttctt ttccaatttt aaaagctgat
      661 cttggtattt cccaagtgaa atttgaacgc gaatagacag taatccatct ttcattcgat
      721 aatagatttt ggggaagtaa ctgatagtct ctctggttcg gctactattc aaatctttga
      781 aaaagccttc actttgagtt tgtttcactt cataccaatg gttctctaga atcatccgag
      841 ctagcttttg tcgatgccac aagcttcgcc aatgatcaag aaaaaagtga atataaagca
      901 atatcatagc tcctgaaaaa gcgagacttc caagcagaca tactaaatct tttatagacc
      961 aaacgatttc aatagtagaa agtgatagct tagaaatatc aaattgtcta aactcttgaa
     1021 aataaaagac gctcatccaa ccgatgaaca gagcgagtag ccagccaaga acaaagtgat
     1081 aaaccaagtg ctgatctcct gcgcgtatgc gatgtccttt gtacattttg atggtttcca
     1141 cctccaatcg aaaaagccca ataggatttc attaggcaat ttcaaaaagt tatgctagtc
     1201 atttactgct acgaggaggg gagttgtttc gtttcaacca attgatttaa aaagccttca
     1261 atagcatccg gcatctccac accaatttct tccaaaatgg attctgcctg ccgacataag
     1321 ttttcattta cttcgacaac tataaagaaa gactcttctt ctcctaacca gtctagtaca
     1381 tcagagtctt cttcactgtc gctattttct ccaagtaaac cttgatgtat aatcagaaac
     1441 attttttcat cagaggttaa tgctttaacg agttgttcct cagtcagctc gccttttcca
     1501 tattgatcga gacaatctaa aatatgttca acattaattt ccataatctt cacctatttc
     1561 tttctttcat tttggttcgt aggatttcct tgattcggct gccgcttcaa gactaaatca
     1621 tccgccttaa tgaaccaatt aacggtagtt ccttctcgaa aaacataatt ggcaacggta
     1681 tccacgattg gattgaccaa ctctacctct gcatcataag caaactcgcg taagggtaca
     1741 ttagctggga tactaacttg aatcattcgc ccttgtgcag aggattttaa attataggtt
     1801 cgttctttta cctcattacc aattgttcca tcctcatttt gcttccgtac ttctcggcgt
     1861 aatgcggaaa aacgcaactt cccaaatgtt aaacctgaat ctacgacaat accttctgtt
     1921 aatctcatct tcttttcctc ctatgctttc actaaatcat caacatacaa cacgtaatca
     1981 gtaaacccac gattctcaat ctcatagcct ttggcaacca aatggggatt cacggctttt
     2041 agcggttggt cttgatcaaa atccttttca ccggcttccg cagctactac cacctcaata
     2101 tcatcggccc gttgcttact ggaatacaaa tgataactgc gaccaatcac cgtagtattc
     2161 cgtccatatc cttctgttat aatttctcct tcaccggcat aacttaactt tccaaaggtt
     2221 tcagccatat ctggcacgac aaatttcaat tccatcttct tttcctcttt tcattgttag
     2281 ttttggatac aaaaatagcg cgactacttt tttaggaggc ggtcgcgcac gttggttctt
     2341 aggatttact tgtatcatct catcacctta gttccggcga ttccagaaat aatagcccgc
     2401 cgtcgcaaaa atcaaagtaa aaccaatgaa cagtaaaaca ttggaatttt tctccccggt
     2461 ttgagggaag gtcttcactg tgggactaga ttcttgagag ccacttggaa cagttggtgt
     2521 ttccggttgt ttcggcgtac ttagtatggt tggaacttct tttggtgtta aggtttgaga
     2581 tttttctttc aaatcttcat tgtgttttcc attgatattc ccatctttat cgtaattgat
     2641 ttccgcaaaa gtaaacttgg ttccttctgg atattttccg gtatctactt ttttcgcaag
     2701 cacagttttg gtgaattctt tatcatttac ttcataatca atcttgccag atttccaaat
     2761 ttctttgttt gtaccatccg gtaataaagc atacagaatt gtttcgaaag cttcttttga
     2821 gccatccagt acatcatgag taatcgacac atcatcaaac atatccacca catcaccatg
     2881 agtaaaggtc tgagaaccgt tttctaggtg ggcctttgtt tggatagaaa catggtgttc
     2941 cactgtacaa ctgacagttt gggcttggtt attcaagcta acatccttcg ctactggctt
     3001 atcgcctgct tcaaaagctt ccttattttc atacacatag ttgaataaga caatagtttt
     3061 atttaaaact tgttcggcgg ttaatttatg ctgaattttc caagttcctg ttttctcttt
     3121 gttcgccaac gttgcgcttg tttctgcaat caccactggt ttggcttttt catctttttc
     3181 ttgggcagct tttgtcgcat ccacatcaat ggcttgcgct accacatacc agtcttcttt
     3241 gatttcatgt agattgtaac tcaatttatc aactagctcg gtagaatcca gagaagttaa
     3301 ttctttgttt ccgtctttcc aagtcgcaag agaagttaaa ctatcttctt cctcaggcaa
     3361 atcatagagc attaaacggt tcaaactaac agaaaatgct ttgttcgtca gcttctcgta
     3421 aggaacggtc accgttttaa ttggttgttt ttggtcttgt tcggtaatgg taaagacata
     3481 ctcactcttc acaaagtctt ctttgttttc cttaaaagta gaacggattt ctaatggcgt
     3541 aatcttttga aaaccttctg gggcttctac ttcttcaagt aaataatccc cataaggaag
     3601 attttcaaac ttgccataac catcaaaccc taattgctcg ttataagctg tggtcgcttc
     3661 atcttcggca cctgtgattt cattggtccc ttccaatggc gacactttaa aggtcagatc
     3721 attgaagcca gtttcggtag tgcccgcagc tgatccagca aatttaaaga aatcaaagcc
     3781 aaagcgaatc acttgttctt ttgccgtaac atttcgggta atcacggcat ttttttcgct
     3841 atcatccacc tttttgatgg atacaggata ctttgtttca tcaaggctat atccttcggg
     3901 cgcttttgtt tcttgccaat aatactcgtt gatagctaaa tgtttaacgg caacttggtt
     3961 cttttcgtct aaagtcaaag tgaccgtttc atcagaacct ttcgttccct tcgctaactc
     4021 tggtttaaaa gcctcactcc atttaacagc ttttccatcc ttagcagtaa acaaggtgta
     4081 ttcagcaccc tcaaagactg ccttaccttg tgctttatcc ccagtatctt tgtcttcttt
     4141 cgtcaaagtg gtttcgccag tgacttcttg attttgccct tttacgttac tggtaacaag
     4201 ggctacggtt tgattggcat acttcaattc gacttttaca ggtttgaacg tattcacgaa
     4261 cccatgacta gctttagttt cggtcacata ataggttccc aattccaacg cattagcaat
     4321 ctcttttggt gtttccgcat gaccgttttc atccgtggtc atttcttgaa cgatttcacc
     4381 ggttggactg tctttgcgaa tggcaaacgt attaccagct aaggaataat tgtcattcca
     4441 aagatcactc cctgtttcaa ctccgctttt atccagaatg atttgccctt tttcccgtgc
     4501 gttttttgaa gtcacgtaaa tggtttcgcc tgctttaatg gtggtagtca tgggggtggt
     4561 atcaatcgta taaggcgccg gtactgattt ttcggtaatg gttacttttg taccatgagg
     4621 aatctcatcc aatgtagcaa tgccttcttt gtcagtagtc acgtcttttg caggtaaagt
     4681 ttttccaaag tctaaatgga aaaccgttcc tggtacaaca tcacccgatt ctttatcgac
     4741 ttttttgatc tttaaagaac cctccgtttc cacatcaatt ttgattgtgt aggtattagg
     4801 tttatcaatc gccccggcca ttaaagtctg ttggccagcc tttttatagg cgacaggtgt
     4861 tccggtacca gcagatttct taagcgtcag cacaccactt tcttttgaat tggcatttgg
     4921 ggtgattatc aactgattac cattcacacg ataatcaatg tttgcggcat tttccacaac
     4981 ctcatcgaac tctgacaaat tcagattatt cgtatccgtc acagtagtcg attgccctaa
     5041 tactgtttta gccgtactat tatggaaggt tggtttcttc tgataatcgt caatggcttg
     5101 atttattttt gcctcaatgg ctgcgatatt tacggcacta ccatctgatc gttttattga
     5161 gtgaagggta tacccattaa cttcttgcca gatcatcttc tgtgccacaa tatgagtatc
     5221 tgcatctgta cctacttttt tccataaaac ggaaactaat ttggctttat cggacatatc
     5281 tggtaacggg tttttctcat agccaggagt gaactcattg taaatcggga ctcctggttc
     5341 aatacagaaa atatcttgtt taaagccgtt gtacactgca taatgcggaa cagtgacttc
     5401 tgacattgga cgaccatcac taaaagttcc ttcaacagca tattgatgtg ctaaatctag
     5461 ttctacggtt accgtttgtg gatgggtaat ttcatcagca aaagtaatcg taggagcaat
     5521 tgctccaaca attgcttgaa cagccaaact caaaatagtt aatacacata atttcttttt
     5581 ttgtttttta tacatgaaat gttctccttt caaattaagc acaaaaaaat aagatgctcg
     5641 cttgaacatc tttgtttata aagtcttttt aaaattttta ttgactgaat agaatggatt
     5701 tgagaatgaa tgagcctaaa aatttaatct aaaatacgaa atatactgcc tttaaattag
     5761 aacacatttt agaacacaaa catttcaaat ttaatcaaat ataataaaat atatttacgg
     5821 gaaaaccttt ataaatcaag gtttttcaaa cttattcaat gatacgaaga aaccaggtct
     5881 taagaaagca cgtaaagctt cacagttttc aaaacgttaa tcgttgttat accaacgatt
     5941 tcagacactt tctcattgcg agaaggtgtc tttttttcgt tctggtaatg agaaaggtaa
     6001 tgacaatatt ataaaccagt gtaagcaatg aatttttcta acgcatttcg ttgagctttt
     6061 tcagtaacat gagaataagt gttaagggta gtttcagcat ttttatgacc caatcgatct
     6121 tgtgtttctt tgatacttgc tccaccttct agtagaagag tagcgtgagt gtgccggaat
     6181 ccatgaatag taacgtgctt aaatttatat ttcttctcta aacgtttcaa tatattattt
     6241 gaatagtccg catgcaaagg ttgattaatg tcaccgtctg catttacata ggtaaagata
     6301 agttgatttt ttgtatttgt atttatgcca aactgcaaaa gctctcgagc ttgttctttt
     6361 ttccagattt ttaacatttc aatagtttgt gcatcaattg gtaatattcg ttcggaagat
     6421 atattttttg tatttttttg aatcctgaca gtttttcttc ttgcattctt ctcttcattt
     6481 cgaatagttg catagctctt tctaacatac attagctgtt cttcaaaata aatgtcagac
     6541 caatgaagag cagctagctc tcctttacgt ataccagtag taatcaaaag ctggaagatt
     6601 aaaatatgtt ttaaaggctc ttctttattg agaatatccc aaaaagcttt tagttcttct
     6661 aatgaaaagt aattttcatt ttctttcttt tcccgctttg gtagatttgt atttgccata
     6721 ggatttcggt gtaatagctc tgcaaaaatg gcatactcaa atatttgaga gctgtaagac
     6781 ttaagctgtt tgatattctt gaattttaaa gcccattcat tgactgcatt ctgacagtga
     6841 acaggagtaa tcttagaaat ggacttattc ccgaattttg gtagtatatg caagcggaaa
     6901 aggtcttttg tacgttgata tgtcgtttct tgtacacgat tcctataaga aggcaaccat
     6961 tcttcataca ctgttataaa caagtcatta gaaggcttat gatagccggt atcttcaatc
     7021 tcgacctttt ttcttgcttc gtgtaacttg gcttcttttt cagttttaaa cccttttttt
     7081 acatagtatt cttgctttcc attttcatct ttacgaacat acaagcggac actatatcgt
     7141 gcaccgcttt ttgttgtgta cttttgtatt gacataacta atctctccaa tctgataact
     7201 tggcgagttg gctgattgaa gaaatagaaa atgagaggag aaaaataatg gatgcaggaa
     7261 ttacagtaat gttagataaa caacaaacga atcaattgaa aaattatgtt tttgaaatga
     7321 caaaagaggc tattgatcaa gcaagaattg ataccggatt agaaagacca tttctaaaag
     7381 gaaaagagat ggctaaatat ttgaatgtat catatacaac ttttttgaaa tttaaaagaa
     7441 tgggattgcc agttatttta ttagaaaaaa tggagttgtt ttcaaaagaa gaatgcaaaa
     7501 aatggatatt gagtcatcaa atttaaaaaa cacctcgttt tttaaatttg atgaagtaga
     7561 aaaaattaaa aagagtgttc ccgtcagttt gcagatcggg ggaacactca ataataaagt
     7621 tctgagaaaa ctttatttga atctattata gcaaataaaa tcagaagcag gtgtgacaat
     7681 gaatgaaaaa gaagttgaaa gcttagttga aaagcaaggc tattctaatt ctgatatata
     7741 tgcagaatta tactatcaat atcctatttt tttaaacgta aatgaaaaat ataagaaaat
     7801 gaaactaagt tctaagttag tttatatgtt actaaaagat agaaatagac tttcattgaa
     7861 aaataacttg tatgatgaga atcaaaaaat ttttttgata tttgaaatca aaaatctcgt
     7921 agaaatttcg ggaatgtcaa aaaatacaat cttatcagca ctagatgaac ttcaaaaagt
     7981 taaacttctt gtgaaaagaa aaaatggctt caataaaagt aaaatgcaaa tgttcccaaa
     8041 tttttattat ttgttaaagc ctgttctgtg caaagatgat gtttataaaa ttaataagat
     8101 aacccatcaa gaaaatagac aaaaaaactt gatagttcaa aatttgaact atggaacaaa
     8161 tcaatattct gttgatagtt caaaatttga actatgcgac acatcaatga aaacaagaga
     8221 caaaaacaat tttgctgata gttcaaaaaa tgaactagaa ttatataagt cttataaaga
     8281 tagtaaagat attaaagaat cacataatga tgatcttctt gaatcacttt caactaaaaa
     8341 taataaatta gatgaagaat tgatcgaaac atttattgaa gaaaatcttc ttaaacaaat
     8401 atggggagaa agtattgtga attgcttaaa actggctagc aatagtgatt atcgtcaatt
     8461 cgacaactgg tacaaaaaat tcaaatatgc gattagatct gctgaaaaag aacaaaaaat
     8521 tcaactgaaa attatctatg aaatttgtaa taacaagtat tttgtagatc atgttagaga
     8581 acagctatca atgactttac gtgacttgat acgaagagca aaaacagatc atcgtatcaa
     8641 acaaaaagac gattatatct ttgcttctct aaaaaataaa gcgttagaac taattgaatt
     8701 gcaaatcagc gaaggaatag ataagcaata agaatagaat tgagtcaaat gaaatggagg
     8761 ggtatctcca cttcatttga gaactttgaa tataggaggg gttattttga ttaaaaatcg
     8821 tttaatagat caagtttggt gtctagatca aaatacagat agtctcgaat taatcgagac
     8881 tatttgcttc aacactatag ttctcgattt aagagctgaa aatgataatt gtgtaactca
     8941 tgtcataatt aatcaaaaaa tggctcagaa gctctctgag agcctcagaa aatgggctaa
     9001 gggaggtaac gatgaaaata attgaaaaaa agattgccaa taaaaaaata aattggttgg
     9061 ttgttaattt tcttgttctg atagctatga ttatttttac aagtaatatt gctcatgcga
     9121 gtattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat aattctcttt
     9181 atagacctta cctaaaaaag tacaatggag atttccttag tcagttcggg atttggctcg
     9241 gatgggctgt ggtaaaaggc atgtttactg tgacagattc gattcaaaat atgattccag
     9301 atgtgctgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt tatcaatcag
     9361 ccgtaaatac aattgtcatt ggattaatga tcctttcatt gatgtttgtt ggttacaaaa
     9421 tgattactgg aaaaggaaca gtggatttaa aatcggttgg aatgaacgta gtgatgtcta
     9481 tagcattaat acttttaatg ccaaccatga tttctagtgg tattcaattt gctaaaacat
     9541 tttataagga ctctactacg attacaaatt cagatgacgg agtcgcttgg tcattgataa
     9601 aacaaggagt aacagattta gcatatatta ataaaacaga tcagtactca agcattgata
     9661 aaacggagga tcgaaataat ttaacacgaa aaaattttca acagacggat ctcacacaag
     9721 tgttaacgga taaagtgatt gataaattgg aaaaagaaaa tccaattgcg gacaatcttc
     9781 gttatgaatt agttgaaaat tctaataatg aatttgttgc tacaaagttt tctgacaact
     9841 tcttatcaac attttctgat agcttgaaat caggctatta ccgataccaa gcaaatctat
     9901 gggggatttc aattgggttg acagcgttag caatcgccta tgtgttcagc gcgtttgtga
     9961 tcattacagc aatactagaa cttgcattta aacgtgtgtt aggtgttctt gtttttgcaa
    10021 cagatattga gacaggacag cgttcaaaag ttgttctatc agatattcta caatgttact
    10081 taactgttgg gtttcaagga tttgggttat caatgtttgc tatgtttatc aattttctga
    10141 actcaggaca aggtatctca acaaatattt ttataaaaac aattgcttat atctgtgccg
    10201 tttttgtttt aatcaaaggc agtggaacag tcatgagata ctttggtgtt gatattggac
    10261 tcaaagaagg ctatgggcaa cttgcttctg cttttggaat gggcgcaatg ctgtttagaa
    10321 aaggatcaaa tggatttaat cgtgctaaag gaagcggaga aggagaagat cgaaaaccag
    10381 aaaagaattt cggcgaaact ctatcaaaaa aagctggcaa aactggaaga gctttgggat
    10441 atgcccatga acgtggatta tccggtttag cttcagatgg agctacaatg gctagtgaaa
    10501 gagcaacaaa accatttaag agtatgcgtg atatagctaa tgataccaag aataagttta
    10561 aagaaggttt agatgatggt acagtgtccg ctattaataa aaatagcaaa cctatgttag
    10621 ctaaaaataa agaagatgaa actggaaaat atgctgattc cgtgccaaca cgtctttcag
    10681 atagaaaaga tggtgctaaa gttgaaaatg ccgatagaat tatgtctagt tctgaacgta
    10741 tgcgtgaagc aatgaaaaat aatgctgaat cgaataataa tcctgcaagc gcaattcagc
    10801 aaaaagtcca acaagatatt gaagaacgta aaaatgctat gcacggtcaa gctaagtctg
    10861 ctgaagaatt aattaatcag aagcgtcatg aagcgaaata cacgcctgaa gcaatgaatc
    10921 gcgaggaaat aatgttaagg aaacgtgtag aagggcggac aggcgctaat attgacggaa
    10981 aagaagcgtt gaccaaagaa agaattcaag aagctaaaaa ttcaaataca ggattagaaa
    11041 aattagtcaa agaaaatcca caaaattcta caagtagtca tggtggccga tcagtagatg
    11101 tccgagaaaa tattcaaggt tcactgaatg gtcatgttgg acggaatgtt gatgtaagag
    11161 agaatttaca aagttcttca aatgctcaag gtactaagac aattgatgtt cgagaaaatc
    11221 tgcaaagtag cagtacaagt caaccaaaaa cagtagatgt tcgagaaaat gtacaaaatt
    11281 ctacaagtag tcaaggattc aaaacagtag atgttcggga gaacattcaa aaagatagtg
    11341 gagaaatgaa agaaaaaaca caaaaaatca atatcgttga agacagaaag tcagcgaaaa
    11401 aatttgattc aaatcatgaa acagtgatta ttgatagtga aatccgtgaa aatgataagg
    11461 gatcaaaatc aagacgaaga ttcacttatg aagacaatga gttattcaga gatacactta
    11521 atgatcctaa tccacttttc gataatttat taagaaataa aaggggggga ttgtcatgca
    11581 attaattcta aagattagta cgcatgattt cttagaactt gacgaattat gtgaatcagt
    11641 aaagaacgca acaaatgaaa aaatcacggt cactaattat attgaactga tgattcaaga
    11701 agaattaaag atgaaaaatg aaatagagag caatttcaaa tgttgctctc tagaaaaaaa
    11761 tgtgagggga taatcaatgg atgataaaca aaaaatgtac gaaaaaaatc gcaaacatag
    11821 tgaggcctta aattttcgtg tcgataaaaa gacttatctt gaactgacat tgattgcaaa
    11881 acaaagggga atttctagag cagacgtttg ccgtgagcgg ttaaagggac tcaaatatga
    11941 accgccgttg ttagctgaag atgatagggt agttttaacc aaacagttaa atcaaattgg
    12001 taacaatttg aatcaagcgg taaaggcatt aaatatcatt gctaaatatt ttagagaaga
    12061 atctgaagat aaaaaagaaa agagcctaca ttttagtttt gatgctagcc gttacaacat
    12121 ttttaaagat gaacttgcga atagcatagc aaaaaagttg atgattagtt atccagatga
    12181 catttttttg gagtccaatc ggagtgcccc ctcttttttt aaattatcag aagtagaaaa
    12241 agaatatttc gaatattgga tagaaaagca aactagaccg ggtacgaaag aagagtattc
    12301 ccaaaaagtt gatcggaatt taattcactc aattcagatt attgcaagtt taaaagatga
    12361 ggtgaaacaa ctttgggagc tactataaca tcgaaaggac gcaagaaaaa tttatcctcg
    12421 ctattacaat atgcagctaa tccttcaaaa aaagaaaaat gtgttgcagt ctcaggaata
    12481 aattgtagtg atgatagtga ggaagcactg caagaaatga atttagtacg taccaagatg
    12541 aataaatcta aagatatagc acaagcgttt catgttattc attcgtttga taagagtact
    12601 tctaaagagt taagtattga taaaatgcac gaaatagctg tcgaatttgc agagaaagct
    12661 tttccaaatt cgcaaatcat tgttgcaagt cacaatgata aagatcattt tcatagtcat
    12721 cttgtcatta ataatattaa catggaaaca tgtaaaaggt tgcgtattga ccctaaagat
    12781 ttagaactaa tgcgaaaaat taacgatcaa gtcctcaatg aacatggtct tgaatcagtg
    12841 aataatgagt actatgaaaa cttagaaaag agaaccaatc tttattcaaa cgatccttct
    12901 aagatgaaat atggaaaaat taattatcaa gagtttgtgc aaaatgcgat cgaagcaacg
    12961 ttggaaaaat gcgaagtgaa ttcttttgaa gatttttcgg atcatttggc aaaagaatat
    13021 aacattgaag tttatcaatt ttcaaaaaca aataacaaac ttggctatgt tctttacaaa
    13081 caaggtgtaa atttctatga gcgtagaggt gagttaatta ctttaggaag agataaacaa
    13141 tctagaaaag aaaaaagtca gtatgtcgaa cgtactttta gtgcaagaaa gttagggaaa
    13201 agatattcat ttgaatctgt ttctgaacaa cttgaaaaga atttagaaga atcacatata
    13261 aaaaattttt ttaatatgga aagagagcaa gttatgtcgc taattagtgg agtaaattac
    13321 aaaactggtg agttaaatgt accgtttgtg gaattagatt ccatcgcaca aaagcaattt
    13381 agcgaccgtg aaggcgatga aaaattcatt aaatatgatg acttcttgcg agaggtagac
    13441 aagcattttg taaatacaat gtctttagaa gatgatcaag aatacacgat taaacttcat
    13501 acggatgtga atcctcaaac tttacgtagt gcgaaaagta aaacaatttc tattaaaaag
    13561 actgatcaga aagagttatt tctaccggca aagggttttg aaaattgttc tcatacacct
    13621 tctgctaaac agattcacta tcaaatcagt cgcataatga atgacgatgt aaaaatgtat
    13681 cgtgctaaaa aggattatga attcacacaa caaatgattg aaaatcagca aaaaaggcaa
    13741 caaaattttg aaatggaatt ctgaatgggc ttgttagtgg actttccagt tttttgccta
    13801 tgaagagttg cttggaaaga agcagttttt aggacatacg ccagctaccc atctacttgc
    13861 cagtcaatcc gccccgctca cgctaggcta ctttctggca agtcagatgg cgggtaaatc
    13921 tctgagggag caagctccct acagactccc tcccaaaaaa agaaaggtgg aagaaaaaaa
    13981 tgaactatcc atattttaaa gtctcggctt cagaagaaac taaagaaata ttcaacaatt
    14041 tttacaacca aaacaaagga atttttggtt caaaggcaaa tatgtttcgt gttatggttt
    14101 caaatttacc agtgttagct agtccatcaa ataataaatt taatgatcct gaaagcatta
    14161 aatttgaaca aaaaatttca gaactagaat caatgataag taatgaagta attgaaaagc
    14221 tggatgacat tgatcaaaag ttatcgtatt ctctaaaaaa caaatacaaa acggaggaga
    14281 aaaaagatgt ttaaagttta cttcccgttt cagtggctcg ttaaaggaat tcttttagtg
    14341 ctactaggat tgattctttt tggaagttat ctaacaatta aagccagaca ttttccagaa
    14401 gaaaagccaa taaaaattgt aacaaaagat ttaaaaatag gtgaaactta tcaggcagat
    14461 ggggttgaac taacatttaa aaatattgaa gtgaccgaaa aaagaaatga atttgcacaa
    14521 catgatcgtg tattacaagt gacctataca cttataaatg atacagaaaa tccgatacgt
    14581 ccacaacaat ggtcgattga aaataaggat ggtgaagaac tttatgagta tgatatgata
    14641 ttggataatc cagagtatat tgaaagtggc aaagaagaaa cagtaaatta ctattatgaa
    14701 ttaccgattg aaaggcagga ctaccaaatc gtagtacgta gagagaatgg ttacatagtt
    14761 gggttgccat ttactttata agttttattt tgttagtagt ttttaaggta atatcagttt
    14821 tgtgattttt gaaaatggaa ctgggagaat ggctgaggaa aataaagttg ttccgtttga
    14881 aacattagtg ataaataagg aagagtttga gcaacttttt cttgattttt ttattcaata
    14941 tgacatgatt tatgatttta gttcgtcact agatttattt gaattagaag cagaaataat
    15001 agaaaacagt cgagagaaga atggtaaaat cattatttca gtagaaaaat tcaatgaatt
    15061 attctcacaa acatttgaaa tagatccaga ctattatcaa ccacaagaag tttttcgaga
    15121 gtttagaaat aagattattg gttttagtca aactacaaaa tgaaagctta ataaagcaag
    15181 tgttgataga attattcctc aacgcttgct ttattttatg ggcacttcat aatagaggta
    15241 tagagaagag aggtattcat tttggatact attactccaa caaacttcaa agaaaatata
    15301 ggtaaagtgt tgcaagaagt agttcattca aattctgaaa tagaaattac tagggattct
    15361 aaaaatggat tgaacgatgg cgtcattatg atttctaaga gaaaatggga gttgttacaa
    15421 gaagaacttt atttacaacg aacgggtaca tgggcttatg tatctgattt a
//
LOCUS       DASHWW010000065        15357 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.065, whole genome shotgun sequence.
ACCESSION   DASHWW010000065 DASHWW010000000
VERSION     DASHWW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.065"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..120)
                     /locus_tag="U2R64_002231"
     CDS             complement(<1..120)
                     /locus_tag="U2R64_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8919023.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTA"
     gene            150..560
                     /locus_tag="U2R64_002232"
     CDS             150..560
                     /locus_tag="U2R64_002232"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919024.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            641..1261
                     /locus_tag="U2R64_002233"
     CDS             641..1261
                     /locus_tag="U2R64_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919025.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1962..2246
                     /locus_tag="U2R64_002234"
     CDS             1962..2246
                     /locus_tag="U2R64_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919026.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2249..3166
                     /locus_tag="U2R64_002235"
     CDS             2249..3166
                     /locus_tag="U2R64_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8919027.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            3159..3941
                     /locus_tag="U2R64_002236"
     CDS             3159..3941
                     /locus_tag="U2R64_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8919028.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3942..4622
                     /locus_tag="U2R64_002237"
     CDS             3942..4622
                     /locus_tag="U2R64_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8919029.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4615..5511
                     /locus_tag="U2R64_002238"
     CDS             4615..5511
                     /locus_tag="U2R64_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8919030.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5706..7355
                     /locus_tag="U2R64_002239"
     CDS             5706..7355
                     /locus_tag="U2R64_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEM8919031.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7949..8884
                     /locus_tag="U2R64_002240"
     CDS             7949..8884
                     /locus_tag="U2R64_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919032.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8877..9647
                     /locus_tag="U2R64_002241"
     CDS             8877..9647
                     /locus_tag="U2R64_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8919033.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            10063..11046
                     /locus_tag="U2R64_002242"
     CDS             10063..11046
                     /locus_tag="U2R64_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEM8919034.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11493..12527
                     /locus_tag="U2R64_002243"
     CDS             11493..12527
                     /locus_tag="U2R64_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8919035.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(12616..12939)
                     /locus_tag="U2R64_002244"
     CDS             complement(12616..12939)
                     /locus_tag="U2R64_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEM8919036.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12926..13633)
                     /locus_tag="U2R64_002245"
     CDS             complement(12926..13633)
                     /locus_tag="U2R64_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEM8919037.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13719..14060
                     /locus_tag="U2R64_002246"
     CDS             13719..14060
                     /locus_tag="U2R64_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HEM8919038.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14231..15079)
                     /locus_tag="U2R64_002247"
     CDS             complement(14231..15079)
                     /locus_tag="U2R64_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919039.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4910 a         2620 c         3237 g         4590 t
ORIGIN      
        1 agccgttaac tccgttttga gaagcgtatt gacagctttt tccaaatgga cacggaataa
       61 ttcattcaaa tcgcctttgt tcgctagagt ctttagaatt tctgtagtaa aatcgttcat
      121 atggaagtcc tcttttctgt gaatgtgttg tggtaactct attctacaga agggacttcc
      181 ttttttctat ttacacaaaa tattttacac tctcgtcaaa tataaaaact agtacgaaat
      241 taatttgtaa attatttaag cttgataaaa taagcaatat cgatgatgta aagtccaaga
      301 tattaacaag aaaagtaagc gaaccagtaa agctaacggc acaagataaa aaaaatggaa
      361 ttgttcttta tggtgatgat gcaaagtata actataattg ggatacctcc tcagaagctg
      421 aggtattaag tattcctact accgatactt caggggaaaa agtcaccttt aaaataaatt
      481 ttataacggc aatttctaag ttggagtatg ggaagcaaaa aaagagagat aacaatgatc
      541 aatatctacc taaaaaataa cgaattaatg atgcatatgt taaagttgtt tttttgaatt
      601 aaacaactca atttattcag ttatatgttc atcgcagcaa gtgaacatta atcgagttat
      661 aaaattaata ggagctaaaa atataaataa agttcgatca gaatttattt ttccagaaga
      721 tttttttaac tggttttttt atcaattcag tgaatgcaag cgactcttag gtgagaatta
      781 ttacttaaaa ggaatcggcg gatttatggg gaatgtggct gatgaacaaa atattataaa
      841 aggaatatct gaacaaacat cagagcttac agtaactaaa gcatttataa gtaatggtga
      901 aagtttgaaa aatgtaactg cgcgaattag aaaagaaaat gaagtagaca ttgtttttgg
      961 aattgaccat gaatgtaatt cagtgatata tgtaacacaa tcagcaaatt taattctttt
     1021 tgagaatggt tgcaaggacg attttatggt ggtctatttg tacgatatac taattccaaa
     1081 acttcgttcc ttatatatgt cttctgaaag tatttttgtg agtgaacaaa agggatcttt
     1141 ctcgaaaaaa ataggtattg aagtaattga atcgattatg tgtcataatc atattacgct
     1201 agaagaatta gaaattttga tagggcaaaa aaataataac acgaaaatac aagtttctta
     1261 gaaatcattt tttattgaga tatctagata aatgatttat tcttcaatca accaactcgc
     1321 caagctgagg taatgttttg aggtaatgat aacatacaac tttttatacc ctagtaaaac
     1381 tctataaaca aagacttatt aatttcgcat gaaatacatt cctgtaaaat gcaataaaat
     1441 agagttttgt ttaaccaggt cttaagaaag cccgtaaagc ttcacagttc tcaaaacgtt
     1501 aattgcgatt atcgttcgag ttcacgagtt acgagaatcg tactgggcga agcaatgctg
     1561 agcgcagtta ccttaatcct aacttttctg gcactttcca caatttggaa agtgcctttt
     1621 ttgtgttttt agctatgtta ataggtagga ttcttggtct ataatatcat tcgatctata
     1681 aacaaacggg aaaaagataa agtatcatca aacaatatta tttatccgct tctgaggttg
     1741 tgacagaagt ggtcagcttc aagaaataag aaggaattta caaaaattgc ttctcatgtt
     1801 tgataaatat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt attcggaaga
     1861 agggattgtg aaaagtcttt tgtcataacc tcttatttgg tagctaattg taaatcccaa
     1921 acggcatgta ttatttttca taagtccgtt tttaaggatt aatgttttct tttgcttttt
     1981 atatggtctg gcttcagcga gaagttccaa cgcatataca aggacgtctg atgtcaacga
     2041 taacaacgat taccatggtg gccagtccac ttggattagc actgtttggt gcgctctttg
     2101 attggcagac aactcaacca cgtctgcgag acagtctgat ttttcttgaa attcaattgg
     2161 aaaatttaca ctttctttat acatttctgg ctgctttctt tatacccgtc aactatactt
     2221 cacttatcaa taagaaagaa ggataagtat ggattttgga aatgaaacgg tcttgaaagc
     2281 aactggtata accaaaaaat acggtgctgc caaagcatta gataaagtat cgatcgaaat
     2341 caaacgtgga atgatctatg gtttgattgg ggagaatgga gcgggtaagt ctacctttat
     2401 gagaactatt atgggtttga tctcgattga tgaaggttcg atcgaattat ttggaacgac
     2461 ggatttgcag gcagcaagac gacgtatggg tcaatcgatt gaaacccctg ctctttatcc
     2521 agaattaact gcaagagata acctacgtat ccaagcagcg aacggcggtg tgtcggatag
     2581 agaaatcgaa gacctgctga aaatgatgcg attggaaaat acagggaaaa agaaagcaaa
     2641 gaatttctct ttaggtatgc gccagcgttt agctattgca aatgcactga tcacgaatcc
     2701 agaatttttg attttggatg aaccgacgaa tgggatggat ccagcaggga tggcagaaat
     2761 gcgagaaatc atccaacgtt tggtaaaaga acggggcatc accgtcttgc tttctagcca
     2821 cttgctagat gaattgtcac agatcgccac tcactacggt attttgcatg aaggacactt
     2881 gatcaaagaa ttatcgaaag aagaattggc acaagaatct cgtcaattta taaaaattga
     2941 cacttcggcg acggaacaag cagtaacggt tctcgactct cttggttata gggattattt
     3001 tgtccaatct agccgtgtta tccagctttt tgaaggaatt gaccaagtag cagccatcaa
     3061 tcaagcattg gtagaggcaa aagttcctgt ggatggtatc cacctagttg ggcaaaaact
     3121 ggaagattat ttcttacaat taactggagg caatccacat gtttaatcta ttaactgctg
     3181 aaaaaataaa agtatggaag agccgtaaaa tgtgggtctc actaggactg atggtcgtac
     3241 ttccgctttt ttattcttgg aacgaatggt atatgcatac aaaatacggc aatgaattaa
     3301 accaagcaac ggatacagtc atcaacggtg caacagggat tttaatggtg gaaaaaatgg
     3361 ctgcatggat tcttctggct ttcgcagcat ttgcgtgctt ttatattggg gaagaatttc
     3421 aaaacggtac gattcgcaat acgttatctt taggacggaa tcgaatgact tattatgtgt
     3481 cgaaacttct cgttacgctt ttgatcacaa cacttggcgt ggttttgatt acggggctag
     3541 ccatgattgc ttacacactt gctttcggat ttggtgaagt tgagggaatc aaaaactatg
     3601 gaaattatgt tctaaaagta tttcctgtat tgcttctgct gatattagcg acattatctg
     3661 ttccagtggc tttgacattc atcactagaa gtaccagtgt cagtttgctt ctttcttttc
     3721 tttatatcat gggaacggcc ttcgttcccg gtgttttcgc aaaaatcaaa ggcttggaat
     3781 ttctaacgga gtggtttacg gaaacgtggc tcatgtatac ggactttgcg caacaagcaa
     3841 cttattcgca agcaccgaaa atgattctgg tcagtctagt aacaatcgtg gtatcatcag
     3901 ctctaggaat gtttattttc caaaaatctg acattaagta ggtgttcctg ctggaaacta
     3961 ttttgattat cgaagacgat gaagctgttc attctttact ggaggaggtt cttgaacaga
     4021 gatacaaact tcttgatgct tattcaggta cggaaggaaa attattgtta agcacatatc
     4081 ctgtcgattt gatccttcta gatctcatgc ttccagggct ttcaggtgaa gcattgttag
     4141 cagaaatccg acagacatcg aatgttccga tcatcgttct ttcagcaaaa agcgatcaaa
     4201 gagataaagt ttccttgttg gcagcaggag cggatgacta tgtgacgaaa ccatttgata
     4261 tcgaagaact gttgttacga atcggcatcc aacttcgtca tcagacttct gtccaagtaa
     4321 aagatctgtc gcaacgcatc tattacaagg aaatcttact ggacaaagag tcgagggatg
     4381 taaatgtgaa tggtgtggct gtccatttga caggaagaga attcgatctg ctgaagcttt
     4441 ttttagaaca tccgaaaaaa gtattttcgc gagcaaatct ttatgaaaca gtttggcaag
     4501 aaccatattt tgatagtgag aaaacagtga atatgcatat ttccaatctt cgagggaaac
     4561 tagcaaaggc acatgctgtg tatattcata cggtgtgggg agtggggttt agatttgatt
     4621 aagtggctgt tgcttctcgt tgttatcttt atgggaagtt ttattttctt cctgcaaagg
     4681 gaaatcaaga gattaactaa gaaaatcgcc actctttctg aacgacaaga atatggtggt
     4741 cgtctttcag tcgaatttcg agaaaagaat ctaatggacc tagtagatgc actgaataca
     4801 tgggtggatg aaaatgaaca aaaaggacaa gcatttcaag aaatggaaga aaacatcaga
     4861 ctatcgatcg tcggcctttc tcatgatctc agaactcctt tgactgctat taacggttat
     4921 gtacaattac tggaacaggt agaggatacg gagaaacggg agaagtattt aacgatcatc
     4981 aaacaatctg ttgcaagatt actcagtatg acggatcagt tttatgatct tgctcgaata
     5041 gagacgaagc aaaaagaaat ggatctccat acgctttctt tttctaaaga ggtggaagaa
     5101 gtatttttct ctttttatga acaattttct gagaaaaata tcgaggtagc gttcgctgaa
     5161 cactcgataa atacaactgt attagcagat ccgctcatgt tgctgcgagt gctgcaaaat
     5221 atcatacaga atttattgcg ttatgcagat ggacaagcaa aggtgacatt ttcaaaagag
     5281 gattcattca ttcgattaac agtggccaat cctatcaaac caggagcgca aacctctgtt
     5341 gaaaaagtct tccagcgttt ttataccgaa aataccagcc gcacaaatac ggaatctagc
     5401 ggaatcgggc tttacctgtc aaaaaaattg gtggaaggaa tgggaggaga gatgaccgct
     5461 agattagacg ggggcatctt ctccatctcc gtcaagttgc ggagggttta attggctcta
     5521 atttacctga agtgaatgac aaaaaattgt atctcgtttt aaagacatct tcttttttgg
     5581 aaggtgtttt tattttggtg tgattgatac gaattaggta acgaagacag ttatttttgt
     5641 accccctttt caaatagcgc aacagtgcta tactaaaact aacaaatcaa ggaacggaga
     5701 gggatatggg ccaaagagaa tttatcgttt taattattat tgcagttgtt attttattag
     5761 ttgttttaga cattttttca cgtttgaaag taaaggaaac agttcgtagt aattggggaa
     5821 aaattcctta tcaaccgaga tttgataaag aagaaagttt gaaggatgcg tggctcacgg
     5881 agaaaaaatt ccgttcatgg gatagtgaaa tcgacgatct tacttggtat gacttggata
     5941 tgttcgaagt atttgaaggg atcaacagta cctattctag tgtaggttca gaagcgttgt
     6001 atcagcgttt acgtagcttt gattttggag aagattatca gttagaaaaa ctaattgctt
     6061 tttatcagga aaatcctcaa ctgagagaaa gaatccaata tcaattcgct cgtttaggaa
     6121 aaaaagatca taattttgca aaacaatatc tagcggatgg aaaaagtaaa aagattggac
     6181 gcgtaggttt atttattttt cttggcttgc ttccgctggt gggtgtaggt ttgcttcttt
     6241 tagggcaagt actaggaatc tatctagcaa tcggtggctt agtattcaat acggtctatt
     6301 atctagtgaa gaaacaaaca ctagaaacag agctgaatag catgagttat ttggtttcaa
     6361 cgatttcagc cgccaatcag ttagcaaaaa tgacgacacc acttcaaaaa gagctgaaac
     6421 agcaaactaa accattaaga gacatcccta aattaggttt ttcatttcga atgaagagcg
     6481 ggagtgaagc agaattgatt tttgaatatg tcaacatcat gttcatgctg ccatttatct
     6541 cctatcattt cgttctcact aaattagaaa agcattcaac tgaagccatc aagctgtggg
     6601 aattgctggg agaattggaa gttgcagcag ccgttttgaa ttatcgcacc tatatgccga
     6661 tcacttgccg accagagttt actgagggcg gtgtgacagc gaaagatatc tatcatccat
     6721 tgttaaaaga agcggtagtt aatccagtca actggcagaa gaatacatta gtcacgggtt
     6781 ccaatgcatc aggaaaatct acgtatgtca aaagtatagc catcagctgt attctagcac
     6841 agacgatcca aacagcgatt gcagaacagt ttaccctgca acctggacat gtgttgactt
     6901 ccatggcaat cgaagatgat ttatttgaag gcgacagtta ttttgtttca gaaatcaaat
     6961 cgatcaaacg tttgctggac caagtggctt ccaaagaacg ctgctactgc ttcgtagatg
     7021 agattttaaa aggaacaaat acgatcgaac ggattgcttc ttccgcttca gtcgttcggt
     7081 ggcttgcgga gtatccatct ttagcatttg tcgccacaca tgatatcgaa ttgacagaga
     7141 ttttaaagaa ttattgtgag aatgtccact ttgaagaaca agtaacagaa ggaaaaggaa
     7201 tcagttttga tttcaaatta aaagaaggac cttcaaggac ccgaaatgcg attgccttgc
     7261 tgaaagtttt gaattatcct aaatccatag ttgaacaggc ccaaaaagaa agtttgttgt
     7321 tcgatgaaca gcgtcagtgg tatccgtttg attaacttta tcaaacgaag catgatgcgt
     7381 gggtccaaaa agacgattat caaaagaagt acattgatgc caaaaaagtg gcagaattca
     7441 atgggaacga gtctgctgtc cagatgatct tggaagattt agcaaaagac gatacaaaat
     7501 aaaccacgct gtcttccttc tagcagcttt tatcgaaaaa acttagcatc agcgacgaga
     7561 cgcacgttcc atggcaaagt tctccgtaaa acaaacagcg aaaacagaaa ttgaaaataa
     7621 ctatttccat tttatttatt tcggttaaaa taaaagaaaa aagctttcga taaaaggacg
     7681 gaggaaagct taacatgaat aaaaaagaca agaacctcag ttataaggat cttctatatg
     7741 tcatcgtagt agttgctgtc ggtactttta tgattttaaa agttccagag ttgtttagat
     7801 agttattcta tcgaagatga tcatgaacta gaaaacacat ctcctctttg ttagcaggtg
     7861 tgtttttgtg tggaagccaa gttgtttttt catctgctgt attccatgat acaattaaga
     7921 atcatgtcta taaggagata ggaaataaat ggcaaatgcg cttgaaataa ataatttgaa
     7981 aaagatctat ggaagtgggg tcgaagcatt gcggggaatc gatctttcgg tgaaagaagg
     8041 agatttctat gcgctattag ggccaaatgg agctgggaag tctacaacga tcgggattat
     8101 tacttcttta gtcaataaaa catctggaaa agtgaatgtc ttcggttatg atctggacaa
     8161 ggatctagtt cgagcaaagc aacagattgg attggttcca caagagttca attttaaccc
     8221 ttttgaaacg gtccagcaaa tcgtcgtgaa tcaagcaggc tactacggtg tctctcgcaa
     8281 agaagcgatg aaacgcagcg aaaaatattt gaagcagtcc aatctttggg aaaagagaaa
     8341 tgtccgtgca cgtatgcttt ccgggggaat gaagcgaaga ctgatgattg ctagggcatt
     8401 gatgcatgaa ccacgtttgc tgatcttgga tgaaccaaca gcaggagttg acatcgagtt
     8461 gagacgcgag atgtgggagt ttctacgaga attgaacgaa aatggtacaa cgatcatttt
     8521 gacgacgcat tatctagaag aagctgaaat gctttgtcgc aacatcggaa tcatccaatc
     8581 gggtgaactg atcgagaata caagtatgaa agagcttctg tcaaaactgc aatttgaaac
     8641 atttatcttt gatttagcgc catatgatac caaacctgtg attgaaggat atgcttgtac
     8701 atttgaagat gagcagacaa tcgctgtcga agttgaacga aatcaagggg tgaacggaat
     8761 cttcgatcag cttacaagac aaggaatcaa agttctttct atgaggaata agtcgaatcg
     8821 tttagaagaa ctgttcttga aaatcacaga agaaaataat catacggagg agaaaaatgt
     8881 ttaatcttta ttttactgca ttaaaaagtt tagctatcaa ggaaacgaac cgctatttgc
     8941 gtatatgggt ccaaacactg gttccgccag tgatcacgac atccttgtat tttgttattt
     9001 tcggaaaaat gatcggtggg cggatcggtg acatgggtgg tttttcatat atggaattca
     9061 tcgttcctgg tttgattatg atgtctgcta tcactagttc gtatgccaat gtttcttcgt
     9121 ccttcttctc tcaaaaattt cagaaaaata tcgaagaaat cttggtagca cctgttccta
     9181 cgcatgtgat tatttggggc tttgtgattg gtggtgtggg tcgcagtatt ctcgtcggct
     9241 ctctcgtaac gatcatttcc ttgttctttg taccacttca tgtgtattca tggttcatgg
     9301 tcatcattac attattgatg acggcaatct tgttttcatt agcaggactg ctcaacggga
     9361 tttttgctca gtcttatgat gatgtatcga tcgtgcctac atttgtcttg cagccgttaa
     9421 cttatctagg tggcgttttc tatgccatct ctatgttacc gcccttttgg caagctgttt
     9481 caaaagtcaa tccgatcgtt tatatgatct ccggtttccg ttacggattc cttggaacga
     9541 tcgatgtgcc agtagcaaca tcgatgatcg tacttgtgtt attcatcgtt gttttgtacg
     9601 ccgttacttg gtatttgatc aataaaggaa gaggattgag aagttagaaa agaggttgtg
     9661 aaatcagcgt tttgacctga gtattagaga aacaaacggg aaaatagttc ctcatatttt
     9721 gttgtttttt gagcgaatac cgagggtcag ctgattgaac accgtttagt ggagaggttg
     9781 tgaaaaagct gttctgcatc aagtaataag aacagccaaa caaaaatagc tcctcctatt
     9841 tttcgtttgg ttggacttat taccgcagat gcaagctttt gaacaccatt tattccggaa
     9901 aatggactgt gataagattt ttgtcacagt cttttttttg ctcaatcaga aacatctttt
     9961 aagctgttca ctttgcttct ttttttgttt cctagtataa tgacaatgtt tttgagaaag
    10021 attgcgactt cactgcttga tagaatggag agtaacaaat aaatgactac taatttttgg
    10081 aaagagctgc caaagccttt ttttgtttta gcaccaatgg aagatgtaac agatgttgta
    10141 tttcgccatg tcgtaaagca tgcagcagca ccggatgtct tctttactga gtttacaaac
    10201 tcagacagtt tctgtcatcc agatggaaaa gacagtgtac gaggaagatt aacatttaca
    10261 gaagatgaac agccgatggt tgcccatatt tggggagaca agccagaatt ttttagagaa
    10321 atgagcattg ctatggcaga aatgggcttc caaggaatcg atatcaacat gggctgccca
    10381 gtccctaatg tagcagaacg tggaaaaggc agtggcttga tccttcgtcc agaagtagcg
    10441 gcacaattga ttgaagcagc taaagctggc ggtttgcctg tcagcgtcaa gacgcgtatc
    10501 ggctatacgg aaatgtctga gatggaagaa tggatcagtc acctacttca tcaagatata
    10561 gccaatcttt ctgtccattt gcgtacgcgt aaagagatga gtaaagtaga tgcacattgg
    10621 gaagtcattc ctaaaatcat tgctttacgt gaccaaatcg ctccacaaac actaatcacg
    10681 atcaatggag atatccccga tcgccagaca ggagaagaat tggccgagaa atatggcgtt
    10741 gatggcatca tgattggccg agggattttc aagaatcctt atgcatttga aaaagacccg
    10801 agggaacata cagaaaaaga actgatcgga ctacttcgtc tgcaactaga tctgcaagat
    10861 cattattcag aaatcatccc gcgttccatc acaggactac atcgtttctt taaaatctat
    10921 atcaaaggat ttccaggagc aaatgacttg cgagttcagt tgatgaatac gaaatctact
    10981 gatgaagtac gagagatctt agagaccttt gaaaaagaac atccaacgct tttcagtgaa
    11041 caatgatttc ttgcttgaac accgtgaatt agaggtcgtg aaaaagctgt cctgtatcaa
    11101 gtaataagaa cagccaaaca aaaatagctc ttcatatttt gtcgtttttt gagctaatac
    11161 cgagggtcag ttgattgaac accgtttata tcagaggttg tgagcctgcc gtttaactct
    11221 gagtcacaag gagcaatttc aaaaaacagc ttctcatgtt tgatgaatat tttgacttgt
    11281 gaccgaagag ttggtaggag aacaccgttt ataagaggtt gtgacaaaag tcttgtcgca
    11341 acctcttttt taaccaaaaa agtgcaaata gtttacttta agtaagagaa taattatgat
    11401 gaataaaaaa ggtggaacaa atagcatact atatatattg aaatgaacac tgtatggatg
    11461 ctccaacttg atgaagctaa ggaggaattc gtatgtcaga aaaggaatta atgaaggtag
    11521 tcggttttta tgaagggttg ccgatcgatg atccaaaaag ctttattgat gaaaaagaac
    11581 agatacctgt acccagttca cgggatcttc tggtaaaagt caacgcagta tctgttaatc
    11641 ctgtcgatac gaaacttcgc caagataacg ggataagaaa tgctttacgt atcttaggtt
    11701 ttgatggagt cgggaaagtt gttgctgtag gtgacgaagt gcaaaaattt tctgtcggcg
    11761 atcgcgtttt ttacgcaggt acaacaagag caggaagcaa tcaagaatac caactagttg
    11821 acgaacgtat tgtcgctctt gcaccaaaaa atctttcaga tgaagaagct gcagccttgc
    11881 cgttgacctc attgaccgct tatgaattgt tatttgaaaa atttggtcta actccagaag
    11941 aaaatgccaa tcgcgggaaa aaaatcttag tgatcaacgg atccgggggc gtcggttcga
    12001 ttttgaatca actagcgcat tgggctggcc tagaagtcta cgcgactgca agtccgaaga
    12061 attttgaatg gctgaaaaaa acaggtgtag actatccaat cgattatcat cacgacttaa
    12121 gtaaaagttt tcgtgaatta ggaatcgatc aagtagagta tgtcgctgta ttattcgata
    12181 ttacccgcta ctttgatcaa atcaagcacc ttgtccgacc atttggacat gtgggaacga
    12241 tcgtagggat caaagagccg ttagatatag gtgtttggaa aaaccaatct atcagcttcg
    12301 actgggagta tatgttcgct aaaacagact ataactatga aatcgaaacg caaggagaag
    12361 ctttagcgca cattgctgct ttagcaaatg aagggattat ccgcagtaca ttgagcaagg
    12421 tctattcaga tgggatgaat gcgaagaact tgaaacaagc aaccaaagac gtagaaacag
    12481 gacatatgtt aggaaaagtc gttgttagtg gtccgttcaa cggataagca agaatacgcc
    12541 gatttttttc ttatttgact ttgataaaaa caagagcgca tgacagtaat ttgccataag
    12601 ctcttgtttt tttatttata ataagcgaat caacgaaagg gaaagaattc ctgccaagac
    12661 gatcaccaat aagctttttg aaagaatagc agctaaaagt gtaggaactg aagccaaagc
    12721 attttcgaga ttgatctgcg gcagatgtcc gatattttgg gtaaatagac tgctgaacca
    12781 taaagcagac ataatgacga tcgggacaaa acttaaatac tcaagcaacg gttgcggtaa
    12841 atcgaatttt ttcagtaaga caaatggtag gaccctagaa agccaagttg ctaaagtaca
    12901 acctaaaata gtcagcaatg taaactcaaa agaaggcatg tttgatccac acccccaatc
    12961 cgcacccaat cagtgttaca actacaatca ctaagttgct tgggataaaa atcagtccga
    13021 catataccag aatcaaagtg agaccaatca ggatcaactg taatcgttta gaggtgtttc
    13081 tatcagaaat gacttgaaga taaagtaacc cgataaacat agcgacgatg gcgaaatcca
    13141 aaccaaactt tttcggatca gtaataaaat tccctaaaag tgcgccaaca agagaagaac
    13201 ccacccacgt caaataagaa atccaattag ctgtattcat ccaacgaaag tttaactttt
    13261 gtccagtata gttcaattta ttcattccca gtgcgaaact ttcatctgtc agcaatgtgc
    13321 caatcagcag attttgaagc agccgatttt tcttgaaata aggagcaatc gtcatactca
    13381 tcagaatcat tcgggaattg actagaaagg tcgagaaaac gatggaaagc aatgggctgt
    13441 gactagcaag catgctgact gtgataaatt gggcagaacc agcatagacc agcagggaca
    13501 tcaacgtgac gactagtgga tgaaatccgg cagctttccc aacgatacca aatgcaagtc
    13561 caataccgat ataaccgaaa acggtaggta acgtgtcttt gatcgcagtt tttatatcta
    13621 acttttcatc caataacaaa actcctttag cacgacataa attttcataa ttgtcgttaa
    13681 acttgtgaat attctaaatt tttaatgagc atttgtcaat ggtgggattg aaacgtaaag
    13741 aactagcggg tcgcagattt acacgtattg tttcggtggg aggaggcgcg aaaaatcttg
    13801 catggctaca aatccaagct gatattttcg atgcaacggt ctattgttta agtgtggagg
    13861 aaggacctgc attaggcgca acaatgattg ctgcactagg gttagggtgg ttcgacacac
    13921 ctgaaagttg ttgtcagaat tttatccaat atacagatgc agtggaacct ctcttacaaa
    13981 atgtagaaaa gtatcataaa atctatcaac aatgccggaa aatctatcca gcaacgaagg
    14041 aaatttgtca tgacttataa aacaaaacgc gtacctaata gtcaaatgac taatattggg
    14101 tacgcgttaa gtcttcttta cttcatcctt tgcatgattc gtgtttttaa agcaaggtct
    14161 gctgtatttc ttgtggattt aggatggttg ttatcgttta cttgctattt ttcattgaaa
    14221 tcgtctttct ttaccgtttc tttagttttt tatctatttt tttcttttgg ttagaaaatt
    14281 ctttttcccg aaagtcttct ttcaggattt ttatagagta gcgttttgaa taagaggcgt
    14341 cagtatgatc gacttggcag acgaaccaag agaacatttg ccttttttct gcatgaggtg
    14401 cttctgctaa taattctttc cataaataat aacagtcctc tatcagaaga agggttcgtt
    14461 catcctcagg ctcccaatag aatgtttcga gagtagcaat cacttcattg atcaattcga
    14521 atgcgggaag ataggcattt tgctgaataa gcgattcaac tgcttcttgg atgaactttc
    14581 gcatctccat gatgaacttc gctgttttcc tgtttttgtt tttcttgata atatgatcgt
    14641 atttatggat gatagttgtt aatttatctg aataatttat tgcatgaaat ggcatcttaa
    14701 ctttgaagcg ttcgataaag tgcggatgtt ctataagaat ctctgttaaa agctcccgta
    14761 caagagagga actagcggag gaaacaaggg acgagagttc ggaaagtgag tagttggatt
    14821 tttttattgg acgttcttcg taagcgaata agacagcagc catgtgtttg catttttttc
    14881 cttctatggc atatagacaa tcacaagtca tgttggtctt ttcatcccaa gtgatcacta
    14941 ccttataatc ttccgtgcca gaaactgttg cggacaagta cttgcttgta tagttcaaat
    15001 gacggacaaa accgtgcaga tgatagctgt aaccgcgttc caaaacgttt tcaggaaaat
    15061 actcaagcca attattcatc tagttctcct ttcatgaaac acttatttat atttagtata
    15121 aagaaacgtt taagaaaaaa gtagctgatt ttacatattt gataatcact tttgctcgaa
    15181 ttgtcaaaaa ttcattctcc ttttcttttc ttagagaatg tgagaaaaag taaaagaata
    15241 gcgtgtttta aagatggaac tttttttgtt ttttatttat ctgacaaaaa tgaagtgatt
    15301 ttgttagaaa taaataattg ttccaattga taaaagaggt atgatgtatc gcaaaga
//
LOCUS       DASHWW010000066        15230 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.066, whole genome shotgun sequence.
ACCESSION   DASHWW010000066 DASHWW010000000
VERSION     DASHWW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.066"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            278..787
                     /locus_tag="U2R64_002248"
     CDS             278..787
                     /locus_tag="U2R64_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8919040.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="U2R64_002249"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="U2R64_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEM8919041.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="U2R64_002250"
     CDS             2322..3302
                     /locus_tag="U2R64_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8919042.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="U2R64_002251"
     CDS             3424..4842
                     /locus_tag="U2R64_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HEM8919043.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="U2R64_002252"
     CDS             4913..6382
                     /locus_tag="U2R64_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8919044.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="U2R64_002253"
     CDS             6392..6859
                     /locus_tag="U2R64_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8919045.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="U2R64_002254"
     CDS             6895..7767
                     /locus_tag="U2R64_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8919046.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="U2R64_002255"
                     /pseudo
     CDS             7848..10382
                     /locus_tag="U2R64_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            10538..11311
                     /locus_tag="U2R64_002256"
     CDS             10538..11311
                     /locus_tag="U2R64_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8919047.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="U2R64_002257"
     CDS             11304..12095
                     /locus_tag="U2R64_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8919048.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="U2R64_002258"
     CDS             12105..12596
                     /locus_tag="U2R64_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8919049.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="U2R64_002259"
     CDS             12614..13024
                     /locus_tag="U2R64_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8919050.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="U2R64_002260"
     CDS             13028..14428
                     /locus_tag="U2R64_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HEM8919051.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="U2R64_002261"
     CDS             14451..14825
                     /locus_tag="U2R64_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8919052.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5285 a         2135 c         3047 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaat
     8881 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     8941 tgaagaaagc atgagtcaat taagagatag aatacttaaa gagtgtgcag gttcttctga
     9001 gtataattat ttagaaagtg acgaatttat agcattaaga aactatgttg ttaataaaat
     9061 atcaccaatt attgattcga caggtctatg tttattagat gaattcttgg cggatatcag
     9121 tctatttata atgtttattg atgtaattga agaaacatca agaaattttt tgctgtctaa
     9181 gttcagaaaa tttcgtatga aaaatgataa acaaaaatta ttggcaaatg agatttggag
     9241 tagtttagaa gtcgaagaaa gtaaacaaga acttttgttg aaatggatac tttttcttgt
     9301 aaagaagttc tatgtgaaaa taccagaaac ccattgtctg atagttatgc acggtaaaat
     9361 aacagcttct gcggatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DASHWW010000067        14496 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.067, whole genome shotgun sequence.
ACCESSION   DASHWW010000067 DASHWW010000000
VERSION     DASHWW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.067"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            136..456
                     /locus_tag="U2R64_002262"
     CDS             136..456
                     /locus_tag="U2R64_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919053.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            908..1108
                     /locus_tag="U2R64_002263"
     CDS             908..1108
                     /locus_tag="U2R64_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8919054.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1255..4044
                     /locus_tag="U2R64_002264"
     CDS             1255..4044
                     /locus_tag="U2R64_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEM8919055.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4091..4618
                     /locus_tag="U2R64_002265"
     CDS             4091..4618
                     /locus_tag="U2R64_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEM8919056.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4639..5829
                     /locus_tag="U2R64_002266"
     CDS             4639..5829
                     /locus_tag="U2R64_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8919057.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5869..7167
                     /gene="asnS"
                     /locus_tag="U2R64_002267"
     CDS             5869..7167
                     /gene="asnS"
                     /locus_tag="U2R64_002267"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEM8919058.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8343..9017
                     /locus_tag="U2R64_002268"
     CDS             8343..9017
                     /locus_tag="U2R64_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEM8919059.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDNIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            9014..9355
                     /locus_tag="U2R64_002269"
     CDS             9014..9355
                     /locus_tag="U2R64_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919060.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            9385..9744
                     /locus_tag="U2R64_002270"
     CDS             9385..9744
                     /locus_tag="U2R64_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEM8919061.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10269..12353
                     /gene="cadA"
                     /locus_tag="U2R64_002271"
     CDS             10269..12353
                     /gene="cadA"
                     /locus_tag="U2R64_002271"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEM8919062.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            12644..14110
                     /locus_tag="U2R64_002272"
     CDS             12644..14110
                     /locus_tag="U2R64_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8919063.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4800 a         2510 c         3102 g         4084 t
ORIGIN      
        1 agaggttgtg acgtggtcac gacctctttt tgacgattat gatacaaaaa acatcattta
       61 tgaacaaaat gtgaataacg ggcgttcttg agatatgatt ttaattggga aaaacttatc
      121 gataaggagg tctttatgaa aaaaagactg ttatggtgtt tgctgtttct atccctaagt
      181 ttaacaagtc agccagtttt tgctgaagaa acacagcggt ctcctattac aggcacacgt
      241 ctgtacaaaa atgtttatgt acagacaaca gatcttgatt ctgcgattcc tgaaacagaa
      301 gaacggtctt tgcagccaag atttggttac ttttggtact gtccgacctg tgattatgaa
      361 agttgctggc atttcttaca ttctacagct gcagcttttg cttttactca tactcagaaa
      421 tatgatggac atcatcctgt tatttatgag gtatagatat gagcaaaaaa gaaaaactaa
      481 tctcgttgat cgtattggtt tgccttgttc ttctggtaac tgtcataggc tatcagaaat
      541 accatgagaa catcagacct actaaagaat cttccccagc ctcgaccgtt gaaacagaac
      601 cgataagtag tcagaaagaa taattttttt agtttaaaga agaacatcag agcaaaaaaa
      661 caccaactga acaatatgtc gtttatttta aaaaaagttc ggtttttcac tttatgtaat
      721 cgctgagaaa acttttttta ataaaaaaag tcgaaaaact ctagcttttt tgtaaacggt
      781 atgatatact ataggagtag tttttgttcg gtaatctgtg gtagcttgtt tcaaataaac
      841 atcttccaga tatacaccat tcaagtaatt gcaaaatatg tgttgataca caaggaggat
      901 ttttattatg gaaacaggta cagtaaaatg gtttaactca gaaaaaggat ttggattcat
      961 cactgcagaa aacggaaacg atgtattcgt tcatttctca gctatccaag gcgacggatt
     1021 caaaacttta gaagaaggcc aagcagtaac tttcgatgtt gaagaaggcc aacgcggacc
     1081 tcaagcaaca aacgttacta aagcttaatt aacctatact aaaaaataaa cgcccagaca
     1141 tttgcgtgtc tgggcgtttt tgtctatttt ctttaaaaag cgatgagagt atttttctgc
     1201 actttgtagt ataatttcaa aagaacatta gaggcaggag aagaggaaga tattttgaaa
     1261 ccaagaactt atgcagtcgt tgatatcgaa acgactggga cgaatccaaa agaagatcgg
     1321 atcatccaat ttggctgcgt catgattgaa tcaggtcgga tcacttcacg tttttcgatc
     1381 gatattcatc cagggcggaa gatttcaaaa caaatccagc atttaacagg gatcacgaat
     1441 caacgcgtcc aaaaagcgcc ttatttcgaa gatgtcgccc aaacgattta caatcttttg
     1501 gcagacacca tatttgtcgc gcataatatt tattttgatt ataatttttt gaaccatgaa
     1561 ctcatgcgat gcggacttcc tagtttgaag ataccaggca tcgatacagt agaacttgca
     1621 caaattttct tgccgacgga accaagcttt cgcttagctg atttgtcaga aagccttgga
     1681 tttattcatg agaatcctca tcaggcagat agtgatgccg aagtgacggg tcaacttctt
     1741 ttgctgatcg aagaacggat gagaaaattg ccaatcatca cgttagagca gattgcgcga
     1801 ttaagtagac acacaggtat ggatacgagt cgtttcattt atcatgtgat tgaagaaatg
     1861 aaagaaaaac cagagccact tgatccctca ttagaaatcg tcgatgggct agctttgcag
     1921 aaaaaagaag tggaactatt cacatccgtc cattatggcg agcggacata tccaagaaaa
     1981 aaacaagcaa aagaaaaaat gtttggtaaa acactgatgt atcgaaaaga acagaacaga
     2041 ctgatgaatg cggtctacga ccatttcaca aaagatgaat caaaagattt gatgatcgaa
     2101 gcagctacag gaatgggtaa aacaatcggt tatctgctgc cattgagtta tttggctaca
     2161 cctgaaaaac ccgctgtcat cagtaccgtt tcgctagttt tgcagcagca gatcatagaa
     2221 aaagacattc cattgctgaa tcaattgcta gatcagccca tacaacctgt aattatcaaa
     2281 agctatcgcc actatattga tttgcagcgt tttaaaggca cacttgtgga accgccagaa
     2341 caaaaacaat atgctttgta tcaaatggcg gtcttagttt ggctgacgca aacgaagact
     2401 ggtgatttgg atgaattaca tttaacaaat ttgaaccatt cattctttgc agatatcgcg
     2461 cacagaggta ttggattttt agcaagaaat cagtcatttt acgaacaaga ctttgttcgt
     2521 ttcttgcaaa agaaaatcag gcaaagtaat tttttgattg tcaatcatgc gtttttagta
     2581 caagaaacac agcgaaaaga accattgctt ccagctagtc catttttgtt gatcgatgaa
     2641 gtacatcatt tgccggaaat cgctgaaaaa gtaaatgaca aacgattaag tattaactat
     2701 ttccataaac aaatccagca attagaagaa ccaaatcagc tgtttgaccg aatacaaagc
     2761 tatttaccga aagaacatga agccttacgc tggttatcga tttatcgaga agaactttct
     2821 gcgctatgcg aagcacagat ttgtatggca gaaggattaa tgagtttagt gagcggcaag
     2881 caacctaacg gacagtatcc agaagaagtc atgatgacaa aagagatgtt ggatcagctg
     2941 ccactggaat ctgggacagc cattgatcac ctgcagcttt tttatcagga gatccagcag
     3001 ctacagtcac aaatgcgtct gacttttgag attatccaag aaagctggac aaaccagatg
     3061 cggatcgatt tagcaagttt atatagccta tttgatcaat tagacaagca atacttgctg
     3121 atggatcaat ggctggaaga ctggcgagat catttgatcc attggttcgt tcctgggaac
     3181 acagcgcagc agatgatttt tcatctccat gattttcaag cggctatgtt gccgtcgact
     3241 gtttggtatc ctcgatatga tcgtattctt tatattggag gaacgctgaa gatcggccct
     3301 aatcgacact atctctctaa gaggcttggc attgaagcag cacctcttaa agtgattgcc
     3361 tctccttatg attatgagaa acaggcaagg atctatgtgc caaaagaggc acctgccgtc
     3421 catcaagtca gcaatcaagc atatatcgat tatttagaga cagcacttac aggtctgatc
     3481 gaacaagaag atcggccaat acttgtgtta ttcacttctc atgatgtttt gcagaaggtc
     3541 tatcagaaaa tgcatctgtc tatgctagaa aaaggacgag aaatactagc tcaagggttt
     3601 ggtggaagcc gggagaagct tttgaaacgc ttcattttgt cagaaaaaag cgtattgttt
     3661 ggcgctgaca gcttttggga aggtgtagat ttgcctggag atgctttgca gatcgttgta
     3721 gtcacacgtt tacccttcga taatccgctt cgcccgatgg tcaaagctag gaacgcttat
     3781 ttagaatcag aggggatcaa tcctttttac caggaatccg tacctaaagc agctttgaag
     3841 ttacgccaag cattaggtcg cttgataagg acggagacag atcgtggcgt attgcttatt
     3901 ttggatcgaa gactagtcac tgcaaaatat ggcgcacgga tcatccatgc attaccgaaa
     3961 aaagtaccga tcaaagagct agctatggag gaaatctatc aggatatcca tgaattctta
     4021 aagaaaaatg aagaaggaag ttagaggagc tgtctttttt cataattaaa atctgctata
     4081 atgaaaagga atgaagataa aggagcgacg acccttgaag aaaaaacaga caaaggaaaa
     4141 aacgattaat cgcgtgttac ttggcttgat cgtattttta ttagcggtca tcgtgatcag
     4201 ctcgattttt tacttgcgtt ccagtcgtcc ggcggtgcag gcgaagaaag aagcagtaga
     4261 aatcgcaaag aaatatgcaa atcttgagga aaccgatcat ttttattggt ttactcgaaa
     4321 gaagacatac ttttcactga caggtacaaa tgataaagga aaagaaatcg ccgttatcat
     4381 tcctaaatct ggtgaaaaag taaaagtatt ggatcaaaca aagggactga ctgaaaacga
     4441 agcaaaacag acaattgctg cggcccatcc tgaaatccaa atcgaaaaag ctgctttagg
     4501 gatgtatgat gatcagcctg tgtgggaagt agtaggaaaa gaaacaaatg ggaaactgaa
     4561 ttattacctg attggctttg aatctggaga tgaagtcaag acaatcaagg gaatttaaaa
     4621 ggtaaaggaa tgaatgggat ggagttatca aaaagaacaa aacgattaga accgtctgtc
     4681 actttggcag ctgcggcaaa ggccaaggca ttaaaagcaa aaggcagaga tgtgctgagt
     4741 ttgactgtgg gagaaccgga ttttgcgaca ccagaaaaca tccaagaagc agcaatcgaa
     4801 gcaatccgca atgggaaagc tagctattat acaccaacag caggaatccc agagcttcga
     4861 caggcaatcg ttgattatct gaagaaaaac tatggacttg tctatgaacc ttcacaaaca
     4921 gtcgtaacag acggagcgaa atttgctttg tatacccttt tccaaacgat ccttgacccg
     4981 caagatgaag tcatcattcc tgtgccttac tgggtcagtt acggtgagca agtaaaactg
     5041 gcagaaggac ttcctgtctt tgtgaaaggg gaagaatcca atagctggaa agttactgtt
     5101 gaacagctag aacaagcacg ttcagaaaaa acaaaagccg taatcatcaa ttctccatcg
     5161 aatccgactg gaatgattta tagcaagaat gaactgcagg caatcggtga atgggcagta
     5221 aaaaatgata ttttgatagt tgctgatgat atttatggcc gtttagttta taatggcaat
     5281 gagtttactc caattgcaac gatttcagaa gcaatcaaaa atcagaccat catcatcaac
     5341 ggcgtgtcta aaacatatgc gatgacaggc tggcgcattg gttatgcggt gggaaatcct
     5401 gtgatcatca atggaatgat cgctgttgct tcccaatcaa ctagcaatcc gacagcagtc
     5461 agtcaatatg cagctgttga agcattgaaa ggtgagcaag atacagtaga agaaatgcgg
     5521 aacgcctttg aagaacgcct gaatacgtta tatccgcttg tggcagaact gccgggtgtt
     5581 tctcttgaaa agccgcaagg agctttctat ctttttccta atgtaaaaga aacgctacgc
     5641 atgtgtaagt atgaaaatgt cacacaatgg gtagaagatc ttttagaaga aacaggggta
     5701 gcgcttgtga ctggcgaagg ctttggggca ccagaaaatg tccgcatgag ttatgccact
     5761 gatcgcgcta cgttagaaga agcggtacgc agaatcaagc aatttattga gagtaaaagt
     5821 caaaattaat cctgaagaaa ttcaaggaat ataaaaggag agtcatacgt ggaacaaatt
     5881 caaatcatcg attcgaaaaa ccatgtggga gaaacagtaa caatcggcgc ttgggtcgca
     5941 aataagcgat caagcggaaa aatcgcattt ttacaattaa gagacggaac agcctttttc
     6001 caaggtgtag ttgtaaaaag cgaagtgtcg gaagaagttt tccaaacagc taaaaatcta
     6061 caccaagaaa catccgtgtt agtaactgga gaaatccgtg aagacagtcg ttcaaaattt
     6121 ggttatgaaa tcggaattac aaatgtggaa gtggtaagcg agagccacga ttatccgatc
     6181 acaccaaaag aacacggaac agatttcttg atggatcatc gtcatttatg gctgcgttct
     6241 tcaagacaac atgcgattat gcagatcaga aatgaaatca ttcgtgcaac gtatgaattc
     6301 tttaatcaac atcattttgt caaaatcgat ccgccgatct tgactggttc tgcaccagaa
     6361 ggcactacgg atctattcga aacaaattac tttgatcaaa aagcttattt atctcaaagt
     6421 ggccaattat acatggaagc tgctgctatg gctttcggaa aagtcttttc attcggtccg
     6481 actttccgtg ctgaaaaatc aaaaacacga cgtcatttga tcgaattctg gatgatcgaa
     6541 ccagaaatgg ctttcactca tcaagaagaa agtttagaag tacaggaaca atatgtagca
     6601 ttcttagtac aaaatgtttt agatcattgc gaatatgcat tagatgtact aggacgagac
     6661 aaagaagtct taaaaactta tacaaaattg ccattccctc gtattactta cgatgatgca
     6721 atcgaattac tgaagaaaaa tggatttgat gacatcgaat ggggcgaaga ctttggttca
     6781 cctcatgaaa cgttcattgc gaattcattc gaacagcctg tctttatcct aaactatcca
     6841 aaagccatca agccattcta catgaaacca catccaacaa gagaagacgt ggtaatttgt
     6901 gcagatatga tcgcaccaga aggttacggt gaaattattg gcggaagcga acgggcaaca
     6961 gactatgatt tcttgctaga acaaatccgt aatcacggtt tggatgaaaa agaatattca
     7021 tggtatcttg atctacgtaa atacggttct gttccgcact ctggttttgg tctaggcctt
     7081 gaacgaacag tcacttggat tgctggtatc gaccatgtac gtgaagctat tccattccca
     7141 cgtttgttga accgaattta tccataagag gtgatgaaaa agctgttctg catcaagtaa
     7201 ttagaacagc caagcaaaaa cagctgttca tgtttttgaa ttggcgggac ttattaccgc
     7261 agatgtaagc ttttgaatac cgtttagtgg agaggttgtg aaaaagctgt ttagtttcga
     7321 gtattaagaa aaattttgtg gaaatggctt tccacatttt tgcataaatt tggcttaata
     7381 ccgagaaact ggcttttgaa caccgtttaa ggaagaggtt gtgaaatcag tgccttgacc
     7441 tgagtattag agaaacaaaa cggaaaaata gcttctcata ttttaccgtt tttttagcta
     7501 atatcgaggg tcagctgatt gaacaccgtt tatatcaaga ggttgtgcgc ctgccgttca
     7561 gctccgagtc acaaggagta atttcaaaaa acagtttttc atgtttgatg actattgtga
     7621 cttgtgaccg aggagttggc cggagagcaa cgtttattta aaaaaaagaa ctgcgaactc
     7681 tcgcagttct ttttttaaaa tacgggataa aggaagtttc cagcagacaa gagaagaaag
     7741 caaaagaaat tgctatttga ttcacaaggt tctataacga aatcgcaatc aatcaaacat
     7801 atacaaagaa ggttattcaa atggaaatct gatttgatga tgcttctgct gttgaaataa
     7861 agcagcatct agtacctgaa aacaaactaa tagtaacatt cgaagatgga gtaggtccgt
     7921 attttcagca tgcaatgatc catatgtaag tttaattcat ccttgaaatc atcggaccag
     7981 ataaagttat gaccaatcta tcccaagcaa tctagaagag atattagtaa aagaacattt
     8041 actggaagtc ttagatgagc ctataaatat atgttctgat ggcgtcatca gtggtctgat
     8101 tgacggaagc ttaggtgtga tcgatttctc tggaccaaac aacgaaggaa tcaaggggaa
     8161 tccggcacgt taagaaaaaa agtataaaaa actagacact tgatgagcgt tcattcaatt
     8221 gattgaaggg actaggctgg tgtcattttt tatacatata ttttctcttt cgtcttgata
     8281 gggcttatgg gataatataa ggaagaaaat catcgtttta ttcaaaaagg agtttttgac
     8341 aaatgaaaaa acgtatatta tttatcggtg acagcattac agacgcagga agagaccgag
     8401 cagaagcaac tgatctaggt aaaggttatc cacttttgat tgccggaaaa ctaatctccc
     8461 aatatccaac gatgaaattt gaatgcatga accgtgggat aggaggagac aatattgcag
     8521 atctgcaagt acgctggcaa gaagattgtt tagctttaca acctgactat gtatcgattt
     8581 tgatcggaat caatgatacc tggcataata ctagcgatca ggctatattc ggaactgaga
     8641 aatctgcgca gcaatttgaa tccgtttatc gaaaattact aaatgaactt caaacagcgg
     8701 aaatctgcaa catcatcttg atggagccgt ttgtacttcc tataaccgac gaccgtcatg
     8761 gctggcgtaa agacttagac cctaaaatcc aaattgttcg taaacttgct aaggaatatg
     8821 gcgcattgct ggttccttta gatggcatat tcaatgcttt agggattgct tatggttttt
     8881 cgaaatatac aagagaagat ggggtccacc caacgattgg cggacatgag atcattgcac
     8941 aaagctggat agatgcaatt gccgcagtcg atttttttag tggagataaa aatgagcgaa
     9001 agaaaagtga gaaatgatgg aaatacggtg ggcagtaaaa gaagatttac ctcaaatcaa
     9061 tcagctgatt actgatcatc cagaatcatt cgtaaaagca aaaacggcag ctgacctaaa
     9121 tgataagaat aaactattgc tcgttgctgt aacaaaagaa aaacggatta tcggatttgc
     9181 gcaagcggac gtgcaacagt cagaagaacg ggtggatcag cgaccatcag gaaaactaat
     9241 ccaacacaca ttagtaacaa aagaaaatac ggaagaaatc caaaaaaaat ttgcagaata
     9301 cttgatgctg gaagctaaaa aaagaagaat aaaatcaatt tttgcccagt tttaatcaaa
     9361 aacagtaata gaaggagaaa tacaatgagt tgtttaggaa atgtcatctg gtttatattc
     9421 ggcggactaa tcggtggtct tagctggtta gcagcgggga tactttggtg tatcacgatc
     9481 ataggtatcc caatcggtat gcaatgtttt aagatcgcct ccctttcttt tgcgcctttt
     9541 ggcaaagaag taatttatca ccagtctggc atgtcattga tcgttaatat catctggctg
     9601 atcgtttcag gcctaccaat tgctctcgca catgtcgtca gcggcatcct tctatgtatc
     9661 acgatcatag ggataccttt tgccaagcaa tctttcaaac ttgctcgatt ggcgttgatg
     9721 ccattcggtg cagaaattgt ataaaaagag aataataaag gttagaaaac gcatagagtc
     9781 aggtgggata catgtatttc acctgactct atgtgttttc ctgtataagt tctcccatgt
     9841 gacttttacg tcttttattt atatgggatt actgtttatg gaaagttgaa ataattttca
     9901 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgaatatc tgggaaggac
     9961 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
    10021 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
    10081 gttggataag agcaggggca atgatcgaag agaaaaagaa agaataagcc aaaacatctg
    10141 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    10201 tgaataacca ttcatttata attagttatg aagagatgtt catatgttga ggcgaggagg
    10261 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    10321 tcgaaaaagg agttcagaag atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    10381 gaaaactaac gattgacgca gaggaagatc atttggctac gattgaacaa gaaacaaaaa
    10441 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    10501 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    10561 gtatcgcttt attgctatta tttgatttta atgaaccaat tcgcttgata gggtatttat
    10621 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    10681 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    10741 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    10801 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    10861 cagctcacgt gcagacgacg gaaggattga tgaccgtgaa ccctgaagac gtgcagatcg
    10921 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    10981 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    11041 ttggtgaaac agtattaagc ggatttatca ataaaaataa accattttta gttcaagtag
    11101 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    11161 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    11221 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    11281 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    11341 tgatttccgt gccacttagt ttctttggcg gtatcggagg cgcaagtaaa atcggtgtat
    11401 tagtaaaagg ttcaaattac ttggagttgc ttgcgcaaac cgagacagtg gtattcgata
    11461 aaaccggcac attaacgaaa ggtgactttt cgatccagac gatcgataca aaaatcgatc
    11521 caaagaaatt catgcaatat attgcgagtg cagaacagtt ttctacacat ccgattgctc
    11581 aatctgtttt agaaggctac gcaggtccgc ttttaccaac aactaatatc caggaatttg
    11641 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagcaggt aatcacaaat
    11701 tgatggaaag atttgaaatc tcttttcctt taagtcaaga aatcggtaca ttgctttatc
    11761 tagcgatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    11821 ccgtagacgc attggttcaa ttaaaacagg ctggtgtgaa gaacacagtc atgttgacgg
    11881 gcgactcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    11941 gcgaattgct tcctgaagat aaagtgcagc ggttagagga aatcttacaa agaaacaata
    12001 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    12061 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    12121 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    12181 aaatcgtcaa acaaaacatt gtctttgcta ttgggataaa aattttggta cttgccttag
    12241 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    12301 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa agaggacgaa tgaacgtcct
    12361 ctttttttta tatccttttc ttaatgaaaa atgtaaagaa aatagatagg attataaaat
    12421 aactaatgtt tttaattttg cagaaaattc aaaatagctt gaaattcaat aaggtcaatg
    12481 aaataaaaga aaataactta tttttttgat ggaaaaaata tgaaaaaacg atgtgtatta
    12541 aataaaagaa tacacacata aaataacact gtcttgtaag tttgttaaaa attgaatatg
    12601 attacatctg gataacaaat ttttatcata aaggagagaa cgaatgaaca acaaacaatt
    12661 acgctggttt actgttgcgt taattgcatt taacatggtt tggggcatgg ggaatgtagt
    12721 taataactat gctcagcaag gagtatcagt tgtcacctct tggctattga ttttggccat
    12781 ttattttatt ccatacgcat tgatcgttgg acaattagga tcagccttca aggatagtaa
    12841 aggaggcgtc agttcatggg tcgaaaatac gacatctaat aaacgactgg catactatgc
    12901 cgcttggact tactgggtcg tccatattcc ttatttggca caaaagcctc aagcaattct
    12961 gattgctggt ggttgggcag tccaaggaaa tggaaatatc gtaaatacga tgtcagtaca
    13021 aatggtagca gttatttcac ttattatatt tcttgccttt ttatatttat caacaaaagg
    13081 actttctact ttgaaagtga ttggcggact ggccggaaca gcgatgttcg tcatgtcgat
    13141 cttatttatt cttttagctg taacggcacc gttcatcaat ccaacgatgg aatttgccac
    13201 accacatatg aatcaagtga aaacatatat tccaacattt gatttcagtt atttcacaac
    13261 cgtttcgatg ctagtatttg cagttggagg ggcggaaaaa atatcccctt atgtcaactc
    13321 tacaagaaat cctgcaaagg aatttcctaa agggatgatc ttcttagcag caatggtagg
    13381 gatttgtgct gtattaggct cagtcgcaat gggtatgctg tttgctagtg ataatattcc
    13441 taaagacttg atggcaaatg gggcatacag tgcttttcaa attttaggta attactatgg
    13501 tatcggtaac tcattgatga tcatttacgc attgacaaac atgattggac aaatctccgc
    13561 attagccttt tcaattgatg caccactaaa aatcttgtta gcagatgcgg atccagaatt
    13621 tgtaccaaac tggctacgta aacgtaatcg taaaggtaca ttggtgaatg gttatcttct
    13681 gacaggtata ctagtaggaa tcattatttt gttgccgatt tttggtatca aagatatgaa
    13741 tgaattagta aaatggttga cgaacttgaa ctcagttgtc atgccaatgc gttacctatg
    13801 ggtgttcttg gcatatatga tgttgaataa agcttataag aaattcaatt ctgaatataa
    13861 atttgttaaa aatccaaaaa tcggttttat ctttggtgct tggtgctttg ccttcactgc
    13921 gtttgcatgt atcctaggaa tggtgccaaa agtagattat actgctgatc ctaaagcatg
    13981 gtggttccaa ttatttacga atatcatcac accaatcgtc ttgatcttat taggtatgat
    14041 cttgccagca attgctcgtc gagacaaaaa caaagaaatc actgaaccag aaacagtggt
    14101 tcagccttaa aatagaaata cttgttacaa gaggttgtga cagaagtggt cagcttcaag
    14161 aaataagaag gaatttacga aaattgcttc tcaaattttt gtgaagtttc ggcttgtttt
    14221 tcgaagaagc tacttctgga acaccgtgaa tcagaggttg tgaaaaagct gtcctgcatc
    14281 aagtaataag aacagccaaa caaaaatagc ccctcatatt tttcgtttgg ctgggcttat
    14341 taccgcagat gcaagctttg gaacaccgtt taaggaagag gttgtaaaat cagcgatttg
    14401 acctgagtat tagagaaaca aacggaaaaa tagctcctca tattttgccg ctttttgagc
    14461 taatgctgaa ggtcagctga ttgaacacca tttatt
//
LOCUS       DASHWW010000068        14202 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.068, whole genome shotgun sequence.
ACCESSION   DASHWW010000068 DASHWW010000000
VERSION     DASHWW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.068"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="U2R64_002273"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="U2R64_002273"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEM8919064.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="U2R64_002274"
     CDS             complement(2261..2512)
                     /locus_tag="U2R64_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEM8919065.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="U2R64_002275"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="U2R64_002275"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HEM8919066.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="U2R64_002276"
     CDS             3462..3680
                     /locus_tag="U2R64_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919067.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="U2R64_002277"
     CDS             complement(3969..4481)
                     /locus_tag="U2R64_002277"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEM8919068.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="U2R64_002278"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="U2R64_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEM8919069.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="U2R64_002279"
     CDS             complement(6934..7377)
                     /locus_tag="U2R64_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HEM8919070.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="U2R64_002280"
     CDS             complement(7378..8166)
                     /locus_tag="U2R64_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8919071.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="U2R64_002281"
     CDS             complement(8163..9104)
                     /locus_tag="U2R64_002281"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEM8919072.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="U2R64_002282"
     CDS             complement(9281..9868)
                     /locus_tag="U2R64_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HEM8919073.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="U2R64_002283"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="U2R64_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEM8919074.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="U2R64_002284"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="U2R64_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEM8919075.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="U2R64_002285"
     CDS             complement(12785..13720)
                     /locus_tag="U2R64_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8919076.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13906..>14202
                     /locus_tag="U2R64_002286"
     CDS             13906..>14202
                     /locus_tag="U2R64_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919077.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         3966 a         3160 c         2509 g         4567 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt atggtacact
    13861 caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac ctacaaacat
    13921 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
    13981 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
    14041 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
    14101 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
    14161 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa gg
//
LOCUS       DASHWW010000069        13429 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.069, whole genome shotgun sequence.
ACCESSION   DASHWW010000069 DASHWW010000000
VERSION     DASHWW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.069"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..914)
                     /locus_tag="U2R64_002287"
     CDS             complement(<1..914)
                     /locus_tag="U2R64_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HEM8919078.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="U2R64_002288"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="U2R64_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEM8919079.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="U2R64_002289"
     CDS             2006..2176
                     /locus_tag="U2R64_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919080.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="U2R64_002290"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="U2R64_002290"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEM8919081.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="U2R64_002291"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="U2R64_002291"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HEM8919082.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /locus_tag="U2R64_002292"
     CDS             4440..5321
                     /locus_tag="U2R64_002292"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEM8919083.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /locus_tag="U2R64_002293"
     CDS             5318..6034
                     /locus_tag="U2R64_002293"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEM8919084.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="U2R64_002294"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="U2R64_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEM8919085.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="U2R64_002295"
     CDS             6751..7752
                     /locus_tag="U2R64_002295"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEM8919086.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="U2R64_002296"
     CDS             7749..9110
                     /locus_tag="U2R64_002296"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEM8919087.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="U2R64_002297"
     CDS             9070..10221
                     /locus_tag="U2R64_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HEM8919088.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="U2R64_002298"
     CDS             10196..11365
                     /locus_tag="U2R64_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8919089.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="U2R64_002299"
     CDS             11540..12919
                     /locus_tag="U2R64_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8919090.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13429
                     /locus_tag="U2R64_002300"
                     /pseudo
     CDS             13200..13429
                     /locus_tag="U2R64_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4485 a         2339 c         2923 g         3682 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatagttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatgtgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caatttttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa gccagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgagaaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcgaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DASHWW010000070        13395 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.070, whole genome shotgun sequence.
ACCESSION   DASHWW010000070 DASHWW010000000
VERSION     DASHWW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.070"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(14..706)
                     /locus_tag="U2R64_002301"
     CDS             complement(14..706)
                     /locus_tag="U2R64_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8919091.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="U2R64_002302"
     CDS             complement(1143..1712)
                     /locus_tag="U2R64_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEM8919092.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="U2R64_002303"
     CDS             complement(1786..2109)
                     /locus_tag="U2R64_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919093.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="U2R64_002304"
     CDS             complement(2263..3075)
                     /locus_tag="U2R64_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919094.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="U2R64_002305"
     CDS             3429..4277
                     /locus_tag="U2R64_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HEM8919095.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="U2R64_002306"
     CDS             4422..5363
                     /locus_tag="U2R64_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HEM8919096.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREIPFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="U2R64_002307"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="U2R64_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7636..9807)
                     /gene="copB"
                     /locus_tag="U2R64_002308"
     CDS             complement(7636..9807)
                     /gene="copB"
                     /locus_tag="U2R64_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HEM8919097.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(9827..12013)
                     /locus_tag="U2R64_002309"
     CDS             complement(9827..12013)
                     /locus_tag="U2R64_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEM8919098.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12013..12222)
                     /gene="copZ"
                     /locus_tag="U2R64_002310"
     CDS             complement(12013..12222)
                     /gene="copZ"
                     /locus_tag="U2R64_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HEM8919099.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12235..12675)
                     /locus_tag="U2R64_002311"
     CDS             complement(12235..12675)
                     /locus_tag="U2R64_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEM8919100.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12749..13288)
                     /locus_tag="U2R64_002312"
     CDS             complement(12749..13288)
                     /locus_tag="U2R64_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8919101.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3761 a         2810 c         2382 g         4442 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acccatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtatgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatccc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaag
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag tcacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgggaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgga tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagttttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaatgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tggaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacctttttt cattattatc tgattttcaa tgtcaaagca tttagagcta caactaccgt
     7681 acttaacgac atcaagacag caccaactgc tggacttaat atgataccaa ttggcgcaag
     7741 aattccggct gctagcggaa ttgcaagaat attgtaacct gccccccacc agaggttctg
     7801 gatcattttc tttcgcgttt gcttggctag atcaagaaaa tgcaaaatat cttttggatc
     7861 gctgtttgtc aatacgacat ccgcagaatc gattgcgata tctgtccctg caccgattgc
     7921 catcccgatt gaagcacggg ctaaacttgg cgcatcattg atcccatcac ccaccatgat
     7981 tacttttttc ccttggtcaa ggtatttctg gacaacagct tctttatcat ctggtaataa
     8041 accgccataa tattcttcga tccctaaata atctgctact gcttgggcag cgtttttatt
     8101 gtcaccagta agcatgacag gagtgatttt tctttctttc aatgttcgga taaattcttt
     8161 tgcttctgtt tttactacgt cacctaaagc aacgattgca gctagatgat tttctaaaat
     8221 caggaagctg atggtatttc cttgttcttg gtaaggtttc aataatgctt gttctacgtt
     8281 taatccgaga cgctcaactt ctttttcatt aactattttc acttgttgtt ttttgactgt
     8341 tgcctctagc ccgactcctg aaagattttt tagattttca gcttgataag gcttgatttc
     8401 atgttctttc aaataattca taatgccaac agccaatgga tgattggcat tcgcttccaa
     8461 ggctcctaga tattgaagga tttcattttt attgaacgca tcatcaagta cttcgacacc
     8521 cgttacagta aattttcctt ctgttagtgt tcctgttttg tccagcatga tcacatctag
     8581 atcattggct tgctccagtg cattgcggtt tttcaaaagt aatccgtttt tagctgctat
     8641 tgatgtggaa cgagcaacaa ctaatgggat agctaaacct agagcatgag gacaggcgat
     8701 gataaagact gttaccatac gttctaatgc attaggaaga tctgtcaaga acaaccaggc
     8761 gatgaatgcc aggataccca caattaatgc gacataaaac agccattttg ccactttgtc
     8821 agataatgac tctagcttgg atttttctcc ttgtgctttt cgcaccattt ccataacctt
     8881 cgctagataa ccattttcac cagttccagt tacttcgatt tcgatcgttc catccccatt
     8941 gatagaaccg ccaatcactt tgtcattggc ttgttttttg attcctcttg attcgccagt
     9001 cacagctgat tcgtcaacaa ttgtttcacc tttcaagatt acaccatctg ttggcatttt
     9061 atcaccagac cggacgatca aacgatcacc ttcgtttact tctttcaatg aaactgtctc
     9121 ttcttttcca tctttcgtca agcgtttcac tgattctggc agtaattctg ctagtttttg
     9181 taaagcattg ctggcattcg acacagcatt catttcaatc cagtgaccta gtagcataat
     9241 aacgatcaaa gtagccaatt cccagaagaa atccatgacg tgtgtatgtg gattgagcag
     9301 atttgcgata aacgaataga cactataaat atatgcaact gtaatcccca tcgcgatcag
     9361 tgtcatcata gcaggacttt tttgtttcaa ttccatctta gctccactta aaaatggctg
     9421 accgccatag ataaatagta tagttgctaa gatcaatacg agccaatcag aaccaggaaa
     9481 cgttacttga aatggaaatt ccattcccat cattggtgaa aaaagaatga ttgggatagc
     9541 taggataagc gatagccaaa atttttgttt gaaattcccc atgtgcatgg aatgatccat
     9601 gccgccgtgt tcgtgatcca tgtgcatcga atggtccatt tgtttgctgt ttgctatatc
     9661 tccatggtta tgtcccatgt gcatggaatg atccatctga ctatggtcat gtttcatctc
     9721 catctgtttt tcatgagatt ctgtactttc tttgtttact acttcttttt tatgctcatg
     9781 ttttttctcc atatcgttcc cattcatttt tactccatcc cttctcttac tttttcatgt
     9841 gtcgatttaa gcacagggag ttcaacaata cactgacgga actaaacgcc atcgctcctc
     9901 ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg aataccaatc gtattataga
     9961 caaaagccca gaaaagattt tgtttgattt ttctcaatgt caacctagac aactcgattg
    10021 tttgtgcaat ggatgccaaa ctgctattca tcagcgtcac atcggctgtt tccatcgcaa
    10081 tgtccgttcc acttcccatt gccataccga catcagctaa tgctaaggcc ggtgcatcat
    10141 tgattccatc gcctgccata ccgacttttt tgccatcttt ctgaagtttt tctacgtagg
    10201 ctgctttatc ctctggaagt acttcagcaa agatatgctt tggatcaata ccaacttgtt
    10261 taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag cataaaaaca tctaatcctt
    10321 tattctggag ctgcttgatt gcttgtttga cttctagttt gatttgatca gccacggcaa
    10381 tcaacccgat cacttgcttt tcatcagcta aaaacatgac tgtttttccc tgctgttcta
    10441 attctaacgc gtgttcttgg tattcatcaa atgataggtt caattcaatt aatcgtttac
    10501 gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct gattccagca cctgggtggg
    10561 ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag ttttccgtat tccacgattg
    10621 ctttacctag tggatgttca gaagcttgtt ctaaagtata aaaaatagat aggacttctt
    10681 tagaaccgac tagatctgta actttgggct ttccttctgt aatcgttcca gttttatcca
    10741 aaacaatgct gtctaagtga gcagctgctt ctaatgcttc tccgccttta attaaaattc
    10801 catttcgtgc accaacaccc gttcctacca taatagctgt tggagtcgct aaacctaatg
    10861 cacatggaca cgcaatgact aatacagaga cactatggat caatgcgagt tgccaatcac
    10921 cagtgatcaa acctgtagct atgagcgtga taaacgcgat gactaatacg atcggaacaa
    10981 aaatccctga gatccgatct gcgatttttt ggattggggc tttgctccct tgagcatctt
    11041 ccaccatttg aatgatttgc gctaatactg tctgcttgcc gacttgtgta acttccatgt
    11101 gaagtagacc attcgtattg attgtcccgc caaagagcgt gtcatccgga ttcttttcta
    11161 caggaagatt ttcaccagta agcatacttt catctatcgc actgcttcct gaaataattc
    11221 gaccatctgc tggaatctgc tcaccaggac ggatgactag ttgatcacca acgactactt
    11281 cttcaatcgc taacgtttct tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa
    11341 gagacatcaa ttgtttgatt gcattacctg ttttcgtttt tgctgtatgt tccaaatatt
    11401 tgccgagcaa aatcagcgtg atgatcatac tgctgctttc aaaataaaga tcttgggggt
    11461 gtccacggaa aaatccgttg taaatgctca atgcaaaggc agccgatgtt ccaattgcta
    11521 ccaatacatc catatttggt gctttcgtct tgattgcatg gtacgcacct ttataaaaac
    11581 gagcaccgac ataaaattgg acaggagcag acagcactaa ctggacgatt ggaaaatgaa
    11641 aaaagtgaac aatcgccgca tggcttccta acatcatagc aatcattgac aacatcaacg
    11701 gcaaagtcaa aaccgtactc aatataagat cgaatagcat ttttttcaaa tacgcttgct
    11761 tttcttctgc aattttttgt ttgtgggctt catcgtacaa aattgcacca tagccgatgt
    11821 tttctacgct ttggattaat ttttcagtgg tcgtcccttc atatttgaca cttgcttttt
    11881 cagtggccaa gttgactgtg gcattgacca caccaggttg tccgttcagc tctttttcga
    11941 tcctagcaga acaatttgca caagtcatac ctgtaatgac gaacgtatcc attttggttt
    12001 ctgctgttgc catcaaatca cctctgcttt ataacccaat ccattgattg cttgacaaat
    12061 cttttcggat tgaacttttg tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt
    12121 tactttcact ttttgcacgc cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca
    12181 atgattgcag ctcatacctt cgattgaaaa ttgttgtttc attttttctt cctcctattg
    12241 atgttgttta cattcacatt gacctgggat acagttacat tcgatcgtat ctactggttg
    12301 cttttgttcc agttgtttca aaatctcatt gatatcttct tgagtcaaag tggcttcttc
    12361 tactagatcc gcaatcgtct ctccaatcct ttttgcacag atatgggaaa aaagattttc
    12421 cgtcgcactg cgaactgttt ccatctccga gacagctgga taataaatga atttttttcc
    12481 ttcttgttct gtccagatca cttctttttt taccaaacga cccagcaaag ttttgatcgt
    12541 tgctggtttc caatccatcg aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg
    12601 tccaagtgtc caaataacac gcatgatctc ccactctgaa tcactgatct ttactggcgt
    12661 tttgactttt tccatttatt tcacaccttt cgtttacaaa tgtaatcatt atcttatgaa
    12721 tacagattac acttgtaaac aaaaactgtc aattattttt gctctctatt ttcaatttag
    12781 ttaaaaattc ttgtttctct cgtcttgttt taaggatgat cagtttattt cttgcattag
    12841 ctacttggat cagctgctgt attttcggtt cattgttttc ttcaaaatgc cagataaaag
    12901 ataaaaattc taagtattcc ctgtttagtt tctccgaaaa tgattcaggc atatctggcc
    12961 gagatttttt gtttatcttt ctttttagag aacgccaaac tactcggtag atggcgagat
    13021 aacgcggcac tttaagccaa atgatcttat ctgcttcttt aatcctttcc tctaatgtag
    13081 aagtataatt tccttcaacg atccatgacg gattagatac cataaacaat tgctgttctt
    13141 gcaaaaacca cttttttgcc tgaatactgt agtctgttgt atgccataaa aggtctagcg
    13201 gcagtagcgg aaagtcggtg atttctttga tcttccttgc gagggtcgat tttcccgacc
    13261 cactttgtcc aatcacgatg atcttcattc ttctccctca cttctctttg gaatttggtt
    13321 cgatcatacc acttataacg ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa
    13381 gtcccttgtt tcgaa
//
LOCUS       DASHWW010000071        13346 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.071, whole genome shotgun sequence.
ACCESSION   DASHWW010000071 DASHWW010000000
VERSION     DASHWW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.071"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(45..1364)
                     /locus_tag="U2R64_002313"
     CDS             complement(45..1364)
                     /locus_tag="U2R64_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8919102.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="U2R64_002314"
     CDS             complement(1361..2014)
                     /locus_tag="U2R64_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8919103.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="U2R64_002315"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="U2R64_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="U2R64_002316"
     CDS             complement(2724..3440)
                     /locus_tag="U2R64_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HEM8919104.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3490..3699)
                     /locus_tag="U2R64_002317"
     CDS             complement(3490..3699)
                     /locus_tag="U2R64_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919105.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            3976..5249
                     /locus_tag="U2R64_002318"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="U2R64_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="U2R64_002319"
     CDS             complement(5356..6387)
                     /locus_tag="U2R64_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919106.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="U2R64_002320"
     CDS             complement(6394..7224)
                     /locus_tag="U2R64_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8919107.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="U2R64_002321"
     CDS             complement(7221..8036)
                     /locus_tag="U2R64_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8919108.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="U2R64_002322"
     CDS             complement(8033..8857)
                     /locus_tag="U2R64_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HEM8919109.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="U2R64_002323"
     CDS             complement(8847..9947)
                     /locus_tag="U2R64_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8919110.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..10910
                     /locus_tag="U2R64_002324"
     CDS             10125..10910
                     /locus_tag="U2R64_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HEM8919111.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10943..11326
                     /locus_tag="U2R64_002325"
     CDS             10943..11326
                     /locus_tag="U2R64_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEM8919112.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11402..11533
                     /locus_tag="U2R64_002326"
     CDS             11402..11533
                     /locus_tag="U2R64_002326"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8919113.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11502..11738
                     /locus_tag="U2R64_002327"
     CDS             11502..11738
                     /locus_tag="U2R64_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8919114.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11816..12787)
                     /locus_tag="U2R64_002328"
     CDS             complement(11816..12787)
                     /locus_tag="U2R64_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEM8919115.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4055 a         2912 c         2306 g         4073 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt catcaaaatg
    10441 gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa actaccaagg
    10501 aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat attttgactc
    10561 actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg gagcattttg
    10621 aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg atggagttaa
    10681 atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc gttcctttgt
    10741 atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt gccgaagatt
    10801 atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta gaaaagttgc
    10861 tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga ttcctatata
    10921 atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag aggcacccat
    10981 ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt gccgatcctt
    11041 gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca gcttgcagcg
    11101 ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat atttgcatgc
    11161 gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt tacgaggaca
    11221 gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg gaatggctcg
    11281 ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc aggatcaagg
    11341 cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg aagaagtttg
    11401 tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc aagctcccct
    11461 ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca cacctttcgg
    11521 ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct ggtgatgaag
    11581 ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt tatcatttta
    11641 atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag ttttttattg
    11701 tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact tggagcttgg
    11761 aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc aagggttaga
    11821 aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga ttgagccagt
    11881 gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact gacttcagca
    11941 aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc cataagataa
    12001 agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc aaatgaggaa
    12061 ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc gctggcgtgt
    12121 ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag cagtggtacg
    12181 gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca atcgtcagca
    12241 gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc acttcgcagt
    12301 taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta tctaagccgg
    12361 tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat gtatccacat
    12421 agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc agtacggtat
    12481 tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc tgaaccagtg
    12541 cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca gcatccttct
    12601 caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt tcaatctgct
    12661 tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc tttaaataaa
    12721 caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt aatactgttc
    12781 cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa ggaaaaactt
    12841 accatttaat cataaaatta gctcatataa atatactagg atgtaaaata gactggtcaa
    12901 aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt ttaatattct
    12961 aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac tatatcacta
    13021 gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta aatggtcatt
    13081 gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg ctgagagtaa
    13141 aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt atttcagatt
    13201 accttaaatg attccattta ctttttatct cattttttcc tactagttag tatcaaatac
    13261 tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag ctaaaacctt
    13321 gtcattacag caaaaaatca cgttat
//
LOCUS       DASHWW010000072        13335 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.072, whole genome shotgun sequence.
ACCESSION   DASHWW010000072 DASHWW010000000
VERSION     DASHWW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.072"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="U2R64_002329"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="U2R64_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEM8919116.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="U2R64_002330"
     CDS             complement(738..1460)
                     /locus_tag="U2R64_002330"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEM8919117.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="U2R64_002331"
     CDS             complement(1596..2477)
                     /locus_tag="U2R64_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEM8919118.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="U2R64_002332"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="U2R64_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEM8919119.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="U2R64_002333"
     CDS             3717..4196
                     /locus_tag="U2R64_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HEM8919120.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="U2R64_002334"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="U2R64_002334"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HEM8919121.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="U2R64_002335"
     CDS             5497..5625
                     /locus_tag="U2R64_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEM8919122.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5629..6174
                     /locus_tag="U2R64_002336"
     CDS             5629..6174
                     /locus_tag="U2R64_002336"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEM8919123.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="U2R64_002337"
     CDS             complement(6628..8319)
                     /locus_tag="U2R64_002337"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEM8919124.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="U2R64_002338"
     CDS             complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="U2R64_002338"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEM8919125.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9801..10820)
                     /gene="argF"
                     /locus_tag="U2R64_002339"
     CDS             complement(9801..10820)
                     /gene="argF"
                     /locus_tag="U2R64_002339"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEM8919126.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="U2R64_002340"
     CDS             complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="U2R64_002340"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEM8919127.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12601..13302
                     /locus_tag="U2R64_002341"
     CDS             12601..13302
                     /locus_tag="U2R64_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8919128.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT         3752 a         2710 c         2368 g         4505 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaatcca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta cggtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa aatccagatg gcctaaagga gaagaaatac cacctggata
     8701 gctataaatc atttcgtaaa tacgaaagac ttaacaaatt aatcagctac gataatcgtt
     8761 ccttcttcag aagctaaaag attctcgata ttttctaaag aagtgatgat tgccttagcg
     8821 tttggttttg cttcaacaaa tgcaatagct gcttctactt tcggaagcat gcttcctgga
     8881 gcgaattgct tttcatcaat gtattgtttc atttctgaaa cagtaacagt ttctaatttc
     8941 ttttgatctg gtttttggta attgacatac acattgtcta ctcctgtcaa tacgatcagc
     9001 aaatccgcat cgatgatttc ggctaatttt tctgaagcaa aatctttatc gattacggct
     9061 tctcgtcctt ctaatccagt agctgtttct acaacaggaa tcccaccgcc accaacagag
     9121 actgtgataa ctccttgatc gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg
     9181 ggtttagggg aagcgactac ttttctccat ccacgtccag catcttcttt gaatgtcaca
     9241 gtggagtcag cattcatttg ttctttggct tcttcttccg tgtagaatgg accgactggt
     9301 ttacttggat ttttgaatga aggatcattt tcatccacaa taacttgagt gactaaagaa
     9361 accacatctt tatcgatccc tttttccttc agtacttcgc ccatggcgtt ttgtaaccag
     9421 taaccgatag atccttctgt cattgcaaca catgtatcta aaggcattgc cggtgttttc
     9481 tcagaatcag cagcttgctg ctgaatcaat aggttaccga cttgcggacc atttccgtgg
     9541 gagatgatca attcatctcc ttgttcgata aatttcacta aatactttgc tgtttccatt
     9601 aacgcttctt gttgggcttt tgcacttgca tccgtagaca agatggcatt gccccctaaa
     9661 gcgacaacta cttttcgttt ggccatttca ttcgtccttt cttcagttct accgaatttt
     9721 ctagataaca aaacgagcca gcgttttgtg attttccctc aatgctgact cgttttttcg
     9781 tgagatgaat gtggttatgc ttaaacgcga gggataaaca agttacctaa tgttgctgcc
     9841 atgatcgctt tgattgagtg catacgattt tctgcttggt caaattgacg agcatatttg
     9901 ctgcggaaga cttcatctgt tacttccatt tcagtgatgc caaagcgttc tttcatttgt
     9961 tcaccgtaaa cagtgtttgt atcatggaaa gctggcaagc agtgcaagaa gatcaaacga
    10021 tctgtgttgt gtgttttttc taccatttcc atattgattt ggtaaggttt caacaatttg
    10081 atacgttctt cgaatttatc ttcttcaccc attgataccc atacatcaga ataaaggacg
    10141 tctgctccgt ctacaccttt atcaacatcg tcggtaatca tcaattgtgc accggatttt
    10201 tcagcaaagc cttctgccat tttgacgatt tcttcttcag gttgtaattc ttttggtgca
    10261 acgatacgca tattcgctcc taaaattgca cctgtgacta ataaagagtt agccatattg
    10321 tttcgaccat ctccgcagta agcaacagtg ataccttcta ctgttccaaa gttttcttgg
    10381 atagttaaaa agtcagcgat catttgtgtt ggatgccatt catcagtcaa gccattccaa
    10441 actggaacac cagagaattc tgctagttcc tctaccattt tttgactgaa tccacggaat
    10501 tcgattccgt caaacatacg tcctagtact ttagctgtat cttctgtgga ttctttttta
    10561 cctaattgga tatcatttgc acctagatat tcaggatgtg cacctagatc gatcgctgca
    10621 gtagtaaatg cagaacgagt acgtgtagat gttttttcaa ataaaagcgc aatatttttt
    10681 ccttctagat agtgatgtgg gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa
    10741 tcgatcaaat attgtaattc ttcttttgta aagtcttttt ctgctaataa gcttcttcct
    10801 tggaatactg attctttcat attaaacatt ctcctttaga ttgtttttat ttaagattaa
    10861 agaggaaatc ccgacggcag ctgacagtaa gactgccgtc aggaaacaaa ttacttcaag
    10921 tcttcacgga caagtggttg gctcatgcag cgtggaccac cacgacctcg tgacaattca
    10981 cttgaattga tttctaacac tttgatgcca tagctacgaa gcaattcgtt cgatacataa
    11041 tttcggttat aagtgactac aacacctgga gcgattgcca atgtgtttga tccatcattc
    11101 cattgttctc gaggtgcaac gatctcatct ccattaccag ttgggatcag tacaagatca
    11161 tctaatccaa gagcagcttt catcgtttcg tgtaagttat ctgaatgagt aatcttgata
    11221 tcatcaccat ctggttcgat tgtaaagaca tccatcttac cgtctttact ttgaattgct
    11281 ggatggatag tgaatttatc gtgatctacc attgtaaata cggtatccaa atgcatcatt
    11341 gcacggttgt tcggaatttt gattgccaac actttttcaa atcctgaatt ttttgcgaat
    11401 aggtggcgtg ctaatttttc taaagctttc gcattagttc gttgagaaat cccaacagct
    11461 actactttat cgcttaagat caattcgtct ccgccttcga tatgatctgg attttcacga
    11521 tccaaccata cttcgattcc tttatttgca aatcttggat gatgtttcaa aatatattct
    11581 gtaaacatcg attcacgacg acgtgcttca aaagtcatct tattgactgt catcccattt
    11641 cccattgatg cggaagggtc gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat
    11701 ggatagtcat cgtctgctga cagatcatat agactgctag aacgtacttc gatatctttt
    11761 gtacgaaccc cagccatgat tttatctacc atttcttgcg tttccattga tagaaggaac
    11821 tcatgaagac cctctcttac agcattcgat gcaatatgag attcatccaa cattttattc
    11881 aagaattgtt ctttgacatt gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa
    11941 agagtctcga cgccttcatt ttgcaatgtc ttcgcaaagt tgtcatgttc ttcttgagca
    12001 atcggaagat atggaatatc atcgaacaac agacgatcca taatatctgg tgtcaaattt
    12061 tccacttctt gtccaggccg tttcagtaaa actgtcttta atttccctat ttcagagaaa
    12121 acgtgaatag gtttatccat gttgtgttgc ctccttcttt ttgattacat gtataggata
    12181 tcctcctttt gtaatcactt tcataatttt gtctcattca aaatgagaca ttcctcacat
    12241 taatattcga taattaaata attaaacgtt tttctatttt taagcgtaat ttattcattt
    12301 tttattctgt atacactttc aaaaaaatat ttattcattg aaaaaatttt tttgaataaa
    12361 ttaaaaaaat aaattatatt atcgttgtta gcgtttacta tatgtattat tgttgttttt
    12421 tatacacaaa tcattcgctt caaaacaaat tattcaatac cattgtatat tttttacata
    12481 ataacaaatt atatttgtaa agtattaaaa cttgtttcta atgttggtat gttaaaactt
    12541 tacaaattct ttaaaaaaag tgacaataaa tatagtgaac aataaggaga ggacttttta
    12601 atgcgtgtta ataaaatcga ttttcacttt tcaaaactca gatatcaacc tgattttgaa
    12661 catttctcgg atgaagagtt ccaacagatc aaggaacata ctgttcttcg ttcttataaa
    12721 aaaggacaga tccttttcga cgatggtgat cccagacaac ggttgtatat cttgaccaaa
    12781 ggactcgttc gtttagaacg ttatgatgaa agtgcaactt attactacta tgactatgtg
    12841 aatacaaata acctttttcc tatgtcagga atgtttggag aagagaccta cacttataca
    12901 gctcaagcga tgactgatat tgaaacattc taccttcctg tttcctacta tgaaaaatta
    12961 gcacgaaaaa atcccgaaca gttgatctat atgatacaaa aaatttctaa agtagttgaa
    13021 atacatgaat tgcgtatcca aatcggattg acctctagcg cctttgaccg ggtaaaacaa
    13081 aatttattca ttttgaaaga agaattgggc gtaccaacaa aagatggtca tatcaccatt
    13141 ccttatccga tcaccttaaa agaattagca gtgaatagcg gcacgacacg tgaaactgct
    13201 ggacaagtaa tcaaacaact acgtgattcc gggctgttag attatgacaa aaagcgtttt
    13261 actttctgta agacagctac tactccagct atgagagaat aacgcgaaca aaaataagca
    13321 gtgaccctga taaat
//
LOCUS       DASHWW010000073        13231 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.073, whole genome shotgun sequence.
ACCESSION   DASHWW010000073 DASHWW010000000
VERSION     DASHWW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.073"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            196..1935
                     /gene="yfcC"
                     /locus_tag="U2R64_002342"
     CDS             196..1935
                     /gene="yfcC"
                     /locus_tag="U2R64_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HEM8919129.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2092..3276
                     /gene="iadA"
                     /locus_tag="U2R64_002343"
     CDS             2092..3276
                     /gene="iadA"
                     /locus_tag="U2R64_002343"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HEM8919130.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3387..3590
                     /locus_tag="U2R64_002344"
     CDS             3387..3590
                     /locus_tag="U2R64_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEM8919131.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3691..4353)
                     /locus_tag="U2R64_002345"
     CDS             complement(3691..4353)
                     /locus_tag="U2R64_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919132.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4366..5868)
                     /locus_tag="U2R64_002346"
     CDS             complement(4366..5868)
                     /locus_tag="U2R64_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8919133.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6416..8095
                     /locus_tag="U2R64_002347"
     CDS             6416..8095
                     /locus_tag="U2R64_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEM8919134.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8222..8701
                     /locus_tag="U2R64_002348"
     CDS             8222..8701
                     /locus_tag="U2R64_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEM8919135.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8920..9600
                     /locus_tag="U2R64_002349"
     CDS             8920..9600
                     /locus_tag="U2R64_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HEM8919136.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9608..10939
                     /locus_tag="U2R64_002350"
     CDS             9608..10939
                     /locus_tag="U2R64_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8919137.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10954..11916
                     /locus_tag="U2R64_002351"
     CDS             10954..11916
                     /locus_tag="U2R64_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEM8919138.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12027..12365
                     /locus_tag="U2R64_002352"
     CDS             12027..12365
                     /locus_tag="U2R64_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEM8919139.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12444..13151
                     /locus_tag="U2R64_002353"
     CDS             12444..13151
                     /locus_tag="U2R64_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HEM8919140.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4231 a         2326 c         2894 g         3780 t
ORIGIN      
        1 aaacagagaa ataaaatact taatataaat ggaaagagaa aaaaataatc atacatagga
       61 gaaaaaaaac aaaatagaaa aaagtgattt tctaataaat tattcatgtg gaaatgtcat
      121 ttttactgta taattcattt gattatccat tttttattca tcaaaattac tgaaaaaaga
      181 aaggaagaaa taaatttgaa gaaaacaaat tcttcaggaa aaccgaaacg cgacttcact
      241 aaattatcga caccccatac gtatgtcatt atttttggtg tagtcatctt tgcatggata
      301 ctgacttttg tcgttccagc aggaaagttc agcacgcaag atattgaata caaagatgca
      361 aatggcgaaa caagtactcg tactgtttta cgtcaagatt ccttccgtta tgcttacgag
      421 ctggataagt cgtatgtgtt tgatcaatta gaagaactgc aagatcatcc agcagaacgt
      481 gaaaaactgg atgttccgga aaaaggattg gaaaaagtca ttgctgacgg agaaaaaaat
      541 cttacgcagg aaaaactaga tgaaatctcc ttgacagatg atgtgcttta cgatcagtac
      601 ggcgaaaata tctatgatac ttctaaaaaa ttgcataaaa cagccaaaat atggggaaca
      661 gatgattttg gcggctttgg tttcttaaat tttgtttttg aaggactagt atctggagat
      721 aagtatggat ctgctgtagg gatcgctgca ttgatccttg ttgttggagg tgcttttggt
      781 attattatgc gtaccggagc gatcgacgca ggtatctatg cgtttatcag taaaactaag
      841 ggactggagc gtttagcttt accgctatta ttctttgctt tttcattcgg tggcgctaca
      901 ttcgggatgg cagaagaggt aattccattc tcaatggtga tggttccatt tgtcattgcg
      961 ttaggatatg actcgatcgt agcagtaacc gtgacttatg tcgcatctca agtcggaaat
     1021 gcgacctctt ggatgagccc gtttagcgta gcggtggctc aagggattgc tggaatcccc
     1081 gtgttgtctg gtgcgacatt ccgattgatt atgtgggtag ttgttactgc attagccgct
     1141 ggttatatga tgatatatgc agaaaaaatc cgtaaaaaac cagaaagttc gttgacttac
     1201 aaatcagatg attatttccg ttctcatatc aaaaagacat ctgatgaaaa taaaaaattc
     1261 atgcttgggc ataaattgat cttattagag atgttagttg tccttgtctg gatcgtttgg
     1321 ggcgtgactc aaaaaggcta ttacattcca gaaatcgctt ctcaattctt tgtgatggga
     1381 ttagttgctg gaatcattgc tgttcttttc aaattagatg gaatgaaagt caatgacatc
     1441 gcttcttctt tccaatctgg tgcagctgat ttagctggta cagcaatcgt agtaggtatg
     1501 gccaaaggga ttcttcttgt cttgggagga tctgatgcat ctgttccttc agctttgaat
     1561 acgattttgc atgggatcgg gacggcgttg accggtgttc cagctgtcat tggtgcttgg
     1621 gcgatgtaca tcttccaaag tttgttcaac ttggttgtta catcaaattc aggacaagca
     1681 gctttgacta tgccaatcat ggctccactg gcagatttag taggtgtatc cagacaagta
     1741 gcagttcttg cttatcagct tggttcaggt tttatggacg cttttacacc cgtatcagcc
     1801 agcttgattg gtgtgctagg tgttgcacgg atcgaatggg caaaatgggc aagattccaa
     1861 atcaagatgc aaggattcct gtttgtttta ggaactattt tcatcatgat tgccattgca
     1921 ataggtctgc agtagtactg gagacctgta aataaaaaag taatccaaac agtagataag
     1981 gactccaaga accgtcattt tacggtaaaa tcaaaggagt aaagatccta tcgtttggat
     2041 tattttttaa gatcctatca tcagttatac ttaaagaaag aggaaaaatg tatgaaaatc
     2101 attcgacaaa ttgaagtgtt tgcaccagat tacttaggaa aaatggatgt actgattgcc
     2161 ggtgggaaga ttttggctgt agaagaacag ctagaaggcg gctacgaagg agtggaagta
     2221 gaagaacttt caggtgaggg aaaagtacta accccgggtt tcattgactg tcatttccat
     2281 attttaggtg gaggaggaga aggcggttat caaaatcgaa cgccagaagt cacattgagc
     2341 caattgacta cagctggtgt aacgacagtt gtcggttgtt tgggaacaga cggagaaggt
     2401 agagatatga ctgcgttgat cagcaaagcg aaaggtctgg aagcagaagg aatctccact
     2461 tatgtatacg aaggttcgta ccgattgccg gtaaaaacag taacagattc tatcatcaaa
     2521 gactttttga caattgataa aattatcgga atcggagaaa tcgcagtatc cgatcaccgt
     2581 tcttctcagc caagttttga agagttcgct cgtgcagtag cagatgctcg tgtaggaggc
     2641 atgttatccg gaaaagctgg gatcatcaat gtccacttag gcggaggaaa aagaaagcta
     2701 gagctattga cacgaatcgt agaagaaaca gaaattccga tcacacaatt tttgcctact
     2761 catgcaaatc gcacaccaga attatttgaa gcttgcgtgg catttgccaa acgtggtggc
     2821 acgattgact tcactgctag cgaagatcct gatttttggg agaagacaga tggtgaagtt
     2881 cgcttcagca aagcactgaa acgattgatc gaggaagatg tttctttaga taatttcacg
     2941 atgacctcag atggacaagg aagcttgcct tattttgatg aaaacaatca tttcctaggg
     3001 ttaggagtag gaagtgccaa ggcattgcta gtagggatca aagaagctgt gcaaaaagaa
     3061 agtatccctt tggaaatcgc cttacgagct ataaccagta atccagcacg tatattgaaa
     3121 ttggataaaa aaggaaaaat cgaaattggt gctgatgcag atctgtgtat cttggataaa
     3181 gaaacgcttg atattgatac agttatcgct aaaggagaaa taatggtcca agaaaaagaa
     3241 gtcaaagtat gggggacttt cgaaaaaagt ttttaatcaa cagctctaac tatctttttt
     3301 agaaaacgag cgttctgttt gtctgtatct gttgttgatg ttaccctgaa ggtagatcaa
     3361 taaacaaact aagaggagga agcacaatgg cagatttaaa aggacgttct aaagatatga
     3421 aagataaagt agtcggtgaa ggaaaagaag catacggcaa agcaacagac gacaagagca
     3481 aagaaacaga agggaaagca caatcactag gtgctgacat caaagaaaaa gctcgaaatt
     3541 taggcgacga agtcaaagac aagttttctc gaaaagacga aaaaaaataa aaaccactta
     3601 ttactaattg aatcaagcaa ataaaaaatc cgaaccatat ctgcgagaca gatatggttc
     3661 ggatttttta tttgatcatt atcctgtttt ttaaacttcg attttttgaa attttttatt
     3721 ttttagttca aagacttcat cacagctttt tgctacttca atctcatgag tcacgatgat
     3781 aatacagcga ttttgttcat gggcgatttc ttggaaaagt ttgacgatat cttgtgaagt
     3841 tgtttcatct agatttccag taggctcatc cgctacgatt agttgatgtt cacagcagat
     3901 agcacgaacg atagcgactc gctgctgctg acctcccgaa agtttggtca cctgtttttt
     3961 tgctaatatt tcatcaattc ctacacgagc cagtcgatct aaagcaactt gtcgataatt
     4021 ctcttgcttg gtcttagtga tttccattgc tgctatgacg ttgtctagag ccgataaata
     4081 aggaagcaag ttgtaagctt ggaaaataat cgagacatca tttttacgat aacttcttaa
     4141 cccgattttg ttcagtgaac gatcttgata gtataccttt ccttcttttg gtgcatctag
     4201 tccagaaata agcgaaagaa aagtcgtttt tccagaacca cttgctccta aaatagcgta
     4261 catttttcca gcttcgaaat tcagttctac atctttataa agcgcatctt gcggatcttg
     4321 ataccaaaat cccaattgtt ctgtccgtaa catcaaattc ctcctttagt ttaataggat
     4381 ttttcttggg tttaatctta atatccctat agaagctaaa aagacagaaa acagactgat
     4441 tccaaatgct actccggcta atagtcccaa ttgtgcaggt ttgacattga tttccaattc
     4501 gctgacttga tcagaaacag caaatggatt attcgtggtt ccttgttgac catcgcgttg
     4561 accgccttgt tcttgtctgt tacctggcat ttgtccaccg ccaggagctt gctggttttg
     4621 tgtcgtggtt tctgtctgtt ggtcaagtag ctgctgtccc acggcattcg cgacgacgtt
     4681 tccgctaagc gaagcaactc ctaatgcaag aatcatacaa atagccactt cggtaaacaa
     4741 ttggagaatg attttacttc tggattctcc taaagatagc aagacgccta actcatgccg
     4801 acgctcccga atggtaatca taatgatcag agtaagtatg ataataccgg ctacagccac
     4861 tagtaaaaca acatttttag aaaaacttgc cacgttgttt aaaggttcca acattgactg
     4921 atacatggaa tcatttgatt gtaagctaaa tgtatctgtg tcgatcagct tctcagcttc
     4981 tttgagaaac tcatccattt tatctggatc agatagagtg taaatagcag aatctatcgt
     5041 gttatcgtca gatgtcccat ttagttcatt tgcaaaagtg taagaagtgt aaagtgtatt
     5101 cgacggattc atgaagttga atttcatacc catactgccg cttgtttcgc tggattcata
     5161 aattcctttg atcgtcattt cataagtggt atcttcatct tcagtactcg tgattgtgaa
     5221 agtatctccg actgccaggt catttgtttc tgctagagta gaatcaatga ctacattgtt
     5281 tgtgcctttg tcgctgtcat ctattccttc accatccgtg atttttgctg ttccatcaga
     5341 aaaattacta ttttgtgcag ttgctgacac accactgatt tgaaagtctg cttgagtcat
     5401 ttgcggattc ccgcccattc ctccagcagg ttcaccgcct gcatcagtag tttctgaact
     5461 gtcttcactt gaatcagaac tagtgatggc agttattcca tcttttgcca tagctgaggc
     5521 ggaactttca aaggaataac tctttacatt atctaattca gctatttttt ccgcgtccgt
     5581 taaggaaact ggtgtaagag aaaaactgcc tggatctgga cgttcttcag tggtagaacc
     5641 gcttgaagaa gtttgttcct gttttttaaa tgaagcttct cgattggcac ttaaagtcac
     5701 tgttgctcca acttcttttt gtgcttgatt cgctgcttct tctgcagcgc ttcgaatcgt
     5761 gaggccagct agcacaaaaa taagaatggc tgtgaacacg gcaaacaata acaatgaacg
     5821 tccccatttt acttttgtac ttttccatgc acgtttcata aaattcatat tttgcatccc
     5881 tcctagtaga tgcatttgat aatagacaac ctatcttaaa gctagcttaa atcttatgct
     5941 gtttgcacac catcaacatg aggttctgta tatataaaaa gtcactatag ttattgcaaa
     6001 aaatgtggta aaatgaaaaa agtatgtttc aaaccgacga agaagaaatg aaagaggaat
     6061 agcaaaagaa atcctagatg ctacagaggg atttttacgt gcatagttgt tctaacaatt
     6121 gctgatacta gcgatttagt ttatttgttg tataataatg gggaacagct gaatacttat
     6181 ataagtattc tggctatagc gtttcgcaaa agatccattt tgttaatgaa gtatatccaa
     6241 aataaaatgc ccatccaact gtcagaacgc ggatgtgctg gtaattttcc tgctgattct
     6301 ccataagttg agaaatagtg attttgcata tgcttcattg gaatggctca tatatttaga
     6361 taaagaagaa aatcgacatc tttaaacttg gatgtcataa gaagaggtga agtttgtgag
     6421 taccattaaa attatcccat taggcggcgt tcgtgaaaat ggaaaaaaca tgtatgtcgc
     6481 agaagtgggc gaggatattt ttattttaga ttgtgggcta aaatatcctg aaaatgagtt
     6541 gttggggatc gacgtcgtaa tccctgattt tacgtattta gaagaaaaca ttgatcgtgt
     6601 agctggtgtc tttttaacac atggacatgc agatgcgatc ggggcacttc cttacttgtt
     6661 gtcaaaaatt tctgtaccag tattcgggac agagttgacg atcgagttag caaaattgaa
     6721 tgtcagtcgt aatgaagcag ccaaaggatt taaggatttc catgtggtag atgagcatac
     6781 agaaatagac tttggtgaaa cagtagtgag ctttttccgt accactcata cgataccaga
     6841 ttcagtgggg atcaatctga aaacaaaaga aggtagtatc gtttatacgg gagattttaa
     6901 atttgaccaa acggctatcc caatgtatca aacagattat gcacgattgg cggaaatcgg
     6961 caaagaagga gtcttagcct tactaagtga atcggcaaat gcagaaaatc ctcagcctgt
     7021 agcttctgaa gcccaaatag cagatgaagt atttgatacg atcaaatatt gggaagggcg
     7081 tatcatcgtc gcttgtgtag caagtaattt gcaacgagtg caacaagtat tggatgcagc
     7141 agaaaaagca caacgaaaag ttgtcttgac tggtcaagat ttcgaacgaa ttattcgcac
     7201 agcgatgcgt ttagaaaaac ttcaattacc aagtgaagat ctgcttgtta cgttgaaaga
     7261 catgaaaaac tatgatccag aagaactgat cattttagaa actggccgaa tgggtgaacc
     7321 catcaagtct ctgcaaaaaa tggcaaacgg tacacaccgt aatgtcaaga ttgaagaagg
     7381 agatttggtt tatatcacta ctacgccaag catcgcgatg gaaaccatcg tggcgaaaac
     7441 ggaagatatc atttatcgag ctggtggaac agtgaagttg atctctgaga atatgcgcgt
     7501 ttctggccat gccaatccta atgacttgca attaatgatc aatttgatga aaccaacata
     7561 ttttgtgcca gttcaaggag agtatcgtga attagctgct catgcagatt tggctcatgc
     7621 agtagggatg ccatacaaaa atatctatat tactggacgc ggagacgtgc tggaatataa
     7681 gaacaagcgt atgagtgttg caggaactac aagtgcagaa aatgtaatga ttgatggatt
     7741 aggcataggt gatatcggaa acattgtttt acgtgatcga aaaatcttgt cagaagacgg
     7801 gattttcgta gcggttgtca ctatcagtcg gcgagaaaag aaaatcattt caaaacctca
     7861 aattacttca cggggattcg tttacgtaaa agctagccgt gatctgatga aagaaagcag
     7921 caatatgatt gaaacaatcg ttgagaaaca tttagaaagc aatgattttg agtggagcaa
     7981 attaaagcaa gacatccgag atcaattagg ccgttactta tttgaacaaa caaaacgccg
     8041 cccagtgatc ttgccagtca ttatggaagc tactcaacgt cgaaataaaa aataaacaaa
     8101 aagagtaaga tgaacctctc tatagagtgc tcgtcttgct ctttttttgc gaaaaacaaa
     8161 taatttttga atacagcatc cctcgcttta taataaacga tagaataaag ggagtgaatc
     8221 aatgatgagt caaacaaaag tcgaacgtta tttagaagaa caaaagatca gctatcaacc
     8281 acttgatttt agtcatgtgg tagaagaatc tttcacagaa gaactacaaa aaagagggat
     8341 tgatccagct ttgatatgta aaactctcgt agtgaaagga aacaaaactg gggtgatcat
     8401 cgcattgatt cctttgaacg atcacttaga ttacaaaaaa acgagacaag tgacgaaaga
     8461 tcgtaaagtt ggttttcctg gaatggattt tgtattaatg catacaggat atccccacgg
     8521 agcaaacacc cctattggaa taaaactcgc acatcctgat tattgttttt tagcagacag
     8581 ttctttaaaa gaaaaagaag aagtaattgt gtcaagcggt gaaatcggga gaagccttcg
     8641 gataaaagta gccgatttag aaaagatcgt ccatcctatt tacgctgatt taattagtta
     8701 agggacgaga agagaagcta agcagagcag agacctcaaa cttgagatta tatctgcttg
     8761 gtacttggtg catcctgtat tatctgttac aattgctttg tacatactgt actatcaatc
     8821 caatgaaaat atatttagca gctatatttt ttcattgatg tgcaagtgat gaaatcgttt
     8881 ttaataaaaa agatacagag aaaacgcgag gtgtaaaata tgaaaattac gtatcatgga
     8941 cattcctgtt taacaattga aatggaaaat ggccaacgcg tgatgattga cccgtttatt
     9001 acaggaaatc cattgacaga cttaactgca gaagaagtaa agacagattg gttgctgatt
     9061 actcatggtc atagtgacca cataggagat atgattccta ttgcaaaaga aaatcaagcc
     9121 acaattatca gtattgttga gattgctgat tatgcgaaca gcagaggagt agattcattc
     9181 ggtatgaata tcggtggaaa acatgcgttt ccattcggcg tggtaaaatt cgtacatgca
     9241 cagcatagtt caagctatga agtagacggt atcgttcagt atatgggcga gcctagcgga
     9301 attattattc aagcagaagg aaaaacgatt tatcatgcag gggatactgc ttatttcagt
     9361 gatctaggat tgcttgcaga agaattcgat attgatgtcg ctttcttgcc gattggcgat
     9421 aactatacga tggggccaga agatgcagca aaggctgcgc aaacaattcg tgccaagaaa
     9481 gtagttccaa tccattacaa tactttccct gtcattgaac aagatcccga atcttttgta
     9541 gagttactgg aagatagtga aggaaaaata atgagcgtct cggaaacgct ggaagtgtag
     9601 gcagaaaatg gcgacaaaac atgatttgat tttagaatat attgaaagtt tacctgttgg
     9661 caatcgaatt tctgtaagaa gcatcgcaaa agaattgaat gtcagtgaag gaacagcgta
     9721 ccgtgcaatc aaagatgcag aaaatgtcgg actagtttca acaattcaac gagtagggac
     9781 catccgtatc gaacgcaaat taaaaaaaca tattgaacgt ttgacatttg gcgaggtcgt
     9841 caggatcatt gaaggggacg ttttaggcgg ggcggcagga ttagacaagg tcttgaataa
     9901 attcgtcatc ggcgcgatga ctaaacatgc catggaacgc tatattacgc caggatcact
     9961 aatgatcgtc ggcaaccggg cggaagtcca aaaattagca ttggaagatg gcgccgcagt
    10021 attgatcaca ggaggattca atacgactgc tgagattgca aagctagctg atgatcttga
    10081 aatgccgatc ttacgcacct cttatgatac atttacagtc gcaaccatga tcaaccgagc
    10141 gttaagcgac caattgatca aaaaagatat catgcttgtc agtgatatct atatgccagc
    10201 tgaaaagact cattatttgc agcagacaga tacgatttct gattatcagc gtttgtcaga
    10261 agaaacgcag cattcgcgtt ttccagtcgt caaccgccat catcgtttga tggggattgt
    10321 tacggcaaaa gatgttttag ggaaatcgcc aaaccagatc atcgatcggg tgatgacgaa
    10381 agaaccaatc agtgtaaaga aaacaatgag tattgcctct gttagccatc aaatgatctg
    10441 ggatgggcta gaagtcatgc cggtcgtttc cgatgacttg acattggaag gcttgattac
    10501 ccggcaagat gtaatgaaag cgatgcagct tgtccagcga caaccgcaga ttgcagatac
    10561 gatttcggat cagatatctg gaaatatcca tacgattgat actgaccgtg aaggaaatcg
    10621 tttggaaaac cctaagttca aattcgtagt agcaccacaa atggtcaatg gcgttggaac
    10681 catttctttt ggcgtactta gcgaaatcat ttctgatgtc gcacaaaaaa caatggtgat
    10741 gaaccaaaaa cgaaatatct tgattgaaca agtgaaccta cattatttgc ggctgatcca
    10801 attggaaagc gaattagaca ttcgtccacg tgtattggaa atcggcagac gttccgctaa
    10861 actggatatc gaagtgttta ttgaaaacac catcgtttcc aaagcaatcg ttgtttgtca
    10921 agtaatggaa cgttcttaga aagcaggagt gaaatgacag tacagcaaga aatagtagat
    10981 acaataaaaa aatacgataa aatcattatc cacaggcatt tgcgccctga tcctgatgca
    11041 ttaggatcac aagtaggatt agccgaacta ttacgggaaa gtttcccaga aaaagaaata
    11101 cgtcaagtag gtgaaacgat tgaagggctt cgctttttag cagaaatgca agaagttgaa
    11161 gatgtcttct accaaggagc gctagtcatc gtgactgata cagctaattc acccagaatc
    11221 agtgatcaaa gatatcagtt ggcagaaaaa ctgatcaaaa tcgaccatca tcccaatgat
    11281 gacccttatg gagatcttgt gtgggtaaat acaaaagcaa gtagctgtag tgagatgatt
    11341 gcagaatttg ctttgatgtt tcctgaatct ttaaagatga acgttaaggc tgcacggtta
    11401 ctttatgcag gaatcgtcgg agatacaggg cgctttttgt atccctccac gacgtcccgt
    11461 acattagaga ttgcttcgat attgagaaat tatccatttg atgcaagtgc tttgaacaga
    11521 gagattgaac aaatgccgat gaaagtcgct aaactttccg gttatcttta tcaaaatatc
    11581 caggtggatg aaaatggtgc aggaagaata atccttccgc aagaaattct tgataaatat
    11641 ggaatcgatg attcagagac agcttcgatc gtttcacttc ctggagtgat tgacgaagtg
    11701 ctggcttggg ggatttttgt tcagcagcct tcagggtatt accgcgtacg tttacgttct
    11761 aaggggccga tcatcaatga attggctaaa cgccatcatg gaggaggcca tccattagca
    11821 agtggtgcga atgcaaaaga tttagcagaa gtagaggaaa tctataaaga gatccaagat
    11881 atatgccaat cgtataagag cagaaaaaca gaatgatact tcgttcgaaa acgtgccttt
    11941 tgtagtaaaa atcacaaatg tatcttttca agatcttctt tttccgttac aatagtgctc
    12001 actaaagatt ttaaaggaga aagaagatga cattaccaaa ttgcccagaa tgtggctcag
    12061 agtacacata tgaagatcga ggcttgttga tttgcccaga atgcgggaac gaatggaaca
    12121 aagaagaaca agaaactgtc atagaagacg gattagtggt attagatgca aatggaaacc
    12181 gtctgttaga gggcgatagc gtgacagtga ttaaagactt gaaagtaaaa ggtgcgtcag
    12241 gtgccattaa acaaggaaca aaagtcaaga acatccgttt agtagaaggc gatcataata
    12301 tcgattgcaa ggtagaagga tttggaccga tgaaactgaa atcggaattt gtgaaaaaga
    12361 attaaagaat attcaaggtc ttttcacatt cttttcctac tactaatgat aaaataaagt
    12421 aaacgaaaag gagtgaaacg aaaatgtatg gttatggaat gtatggtttt ttagatccga
    12481 catttctttt ggtcattctt ggattagtta tttccggaat tgcgtcagcg tacgtcaata
    12541 gtactttccg aaaatacgat caagtgagaa gcaaaaacaa tgtgactggt acacaagcag
    12601 cacaatatat attacaaagt caacagataa ataatgtcgg tgttcaacaa attgccggag
    12661 atctcacaga taactacaat tcaggtaata agatgttgag tttgtctcaa gcaactgcac
    12721 agtctacttc agttgctgcg ataggtgtag cagctcatga atgcggacat gcggtacaag
    12781 atgcttcggg ttatgtccca ttgaagattc gtgcagcact tgttccagca gctaactttg
    12841 gttcgatgat ttcgttcccc ttgattatgg taggtgtatt gcttagctgg aactctacgt
    12901 taatcaatat cgggattttc gctttttctt tagcattact tttccaattg gtgacattac
    12961 cagtcgaatt taacgcgtct cggcgagcaa tccaaatttt gagtgaaggc ggactactga
    13021 cggaagaaga agtaccgatg gcaagacacg tattatttgc agcagcactg acttatgttg
    13081 cagcagcgct ttcgacattc ctgcagctgt tgcgcttgat cttattgttc ggcggcaacc
    13141 gaagagatta aaataaagaa gttgtgaaat cagcgctttg atctgagcta ataccgagag
    13201 ttagctgatt gaataccatt tatttggaat a
//
LOCUS       DASHWW010000074        13090 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.074, whole genome shotgun sequence.
ACCESSION   DASHWW010000074 DASHWW010000000
VERSION     DASHWW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.074"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            221..553
                     /locus_tag="U2R64_002354"
     CDS             221..553
                     /locus_tag="U2R64_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEM8919141.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQNKTVVQCKKYI
                     IQKDKVSEEMIYYVGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1173..1514
                     /locus_tag="U2R64_002355"
     CDS             1173..1514
                     /locus_tag="U2R64_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEM8919142.1"
                     /translation="MKNYDPNIRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEEDLYDQKLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            1628..1867
                     /locus_tag="U2R64_002356"
     CDS             1628..1867
                     /locus_tag="U2R64_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919143.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            1934..2173
                     /locus_tag="U2R64_002357"
     CDS             1934..2173
                     /locus_tag="U2R64_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919144.1"
                     /translation="MNCKESVNWKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKTSSNCQLLLEVS"
     gene            2300..2989
                     /locus_tag="U2R64_002358"
     CDS             2300..2989
                     /locus_tag="U2R64_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEM8919145.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDDVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYPDAEMGNGNYILAGYNVDTPSVLLSDMIDLSEGEEIDLIDA
                     HYKYQYEVSKRGKIYDYSQVVQSKENNSFLSLPKAGKKPLLTLLDFEANNMKKCDVIQ
                     CELVNVEKINK"
     gene            2995..4161
                     /locus_tag="U2R64_002359"
     CDS             2995..4161
                     /locus_tag="U2R64_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HEM8919146.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTEFTVFDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFVILEILPKKIFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFALSMILLLSFLWLL
                     VRKCELTNGQLTFLWAFLAIMCQSFMEETLATISWVPIVFLMLAMATHQYKTTR"
     gene            4243..4914
                     /locus_tag="U2R64_002360"
     CDS             4243..4914
                     /locus_tag="U2R64_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEM8919147.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFRLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            4966..6942
                     /locus_tag="U2R64_002361"
     CDS             4966..6942
                     /locus_tag="U2R64_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8919148.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQAHAEDVTQKTPPEKVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVIYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTEQSKQTPLKGAKFELYKGEPGKGSKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQVGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            6955..7707
                     /locus_tag="U2R64_002362"
     CDS             6955..7707
                     /locus_tag="U2R64_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8919149.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVSKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            7723..8478
                     /locus_tag="U2R64_002363"
     CDS             7723..8478
                     /locus_tag="U2R64_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919150.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADSQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLVSNGETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSEKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            8491..8751
                     /locus_tag="U2R64_002364"
     CDS             8491..8751
                     /locus_tag="U2R64_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919151.1"
                     /translation="MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            8748..10838
                     /locus_tag="U2R64_002365"
     CDS             8748..10838
                     /locus_tag="U2R64_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8919152.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRQDAVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVDYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            10865..11329
                     /locus_tag="U2R64_002366"
     CDS             10865..11329
                     /locus_tag="U2R64_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919153.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            11326..11568
                     /locus_tag="U2R64_002367"
     CDS             11326..11568
                     /locus_tag="U2R64_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HEM8919154.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            11586..11888
                     /locus_tag="U2R64_002368"
     CDS             11586..11888
                     /locus_tag="U2R64_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919155.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            11958..>13090
                     /locus_tag="U2R64_002369"
     CDS             11958..>13090
                     /locus_tag="U2R64_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919156.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKER"
BASE COUNT         4716 a         1988 c         2706 g         3680 t
ORIGIN      
        1 aaaaatacgt gatattacga tgaatctatg cctaagcata atgttataaa aatgtccgtg
       61 tggctctttg ccgtatgatg aacgctgaaa ttagagggaa cgcatgtttg gatgcgttcc
      121 ctcttttttg tttgtcatga acgaaaatca attctctatt tttgaaaaat aacaagaaaa
      181 acttgttaaa aatatttaaa gtaagtgggt ggattatttt atgtcatata caggaatttt
      241 gagtctcgaa gatatttgtc actacggtaa acggtgtacc gctacagaga agatcacgaa
      301 gaaactatca actggccaaa ataaaaccgt tgtgcagtgt aagaaatata taatccaaaa
      361 agacaaagtc tcagaggaaa tgatttatta cgttgggaaa caaaagcaaa taattttaaa
      421 agatcctatc cctttaaaag agctatatcc aacaatcaaa catgtttatg accaaaacgg
      481 tgtattgata ggtcgaagaa aaaatggagt cttacgttgt accgcaaaag ggatggggcg
      541 tttgatcagc tgaattgatc attcttataa cttgtatttt atcgtttttc gcttgcttga
      601 aaatattgtc gagacttcta aaagaactta gaatcactag aaaaataagg agtagacttg
      661 atctatcaac aattcccttc ggggagtgat ggggtaggtt tttacgattg gtaacgtaaa
      721 aaattggtca atcgagtaaa tgcccttgtt tggatagtgg tgaaatgaat ttgtgtaaat
      781 aatatgcaca gagtaaacaa gagggaattt agaagttaga caagttagaa tagcgcctag
      841 attaatcatg agcagctact aagggatcta ggctttgacg caaactcatg gaataaggag
      901 taggtcttct cgtaatgggg aggacgcaca agaaattgtg tcgtgtgctg cagtacatgt
      961 agatacttgc gaggacgttg attattggat caatcgagca tttaccgatg ttctactagg
     1021 gtttctcgtt tcggacgcca taaacgagtc gatatttttt atgtattttt aagtaaacga
     1081 aaaacgataa aatatgaacg agtcctgaat aaagtgaaaa aattgatata aaacatagag
     1141 aaaatgaaat ttacgtaatg gaggaatgac aaatgaaaaa ttatgatccg aatatacgat
     1201 ggggcacaca tactattaag gtttctttcc aacgttggga ttacaaagga tttgtgacgt
     1261 ttagaagagg cggaaattgt aaaggattag atgttttagc attagacgag gaagatttat
     1321 acgatcaaaa attgactgat aatccaattg gattcggctt gctacctgaa gatgatgaag
     1381 gtaatgaatg gtttaaaatg acgcttatga atgataatgg agacgaatta tctgttgaag
     1441 atacttggtc atatttgagt gattatattg tcagcgttga aatcattgaa tttgtagcgg
     1501 ataaagaaga ataaaaactg gaggaataaa ttttacagat aaaggcttag aaggagtcac
     1561 gacgattaat aaaaaggtag tattacctta ggcattgagt aaggaattta tttaggagga
     1621 aaattagatg gcgcgaccag ttttagaggc gatggatatg gatactttga caaaaggaag
     1681 gtatgtacag ctgttagctc gtggttattc acctaaagat gtattcaaag ccctatctaa
     1741 aggaacagat atggaaaaag aaagattacg aaaagaattc gattattgga gaacccataa
     1801 tggaatcaag gatttgaaac cagcacggcc agtaattaaa cgaaagaaaa agataaccca
     1861 agactgaagt gtagagcgta tgtgatcata ggctttttta tttttgcaaa aaacagggaa
     1921 ggtaggaaaa ctcatgaatt gtaaagaaag cgtaaattgg aaaaaagtgt caaaagaaat
     1981 ggaagaaaag ttgctaaaaa tgatgaaaca aaaacacctt aaaagattat ctgtcatgca
     2041 atatatcaat gatatgcaga taacaggaaa ggagaaagcc tgtctattgg gatcaatgaa
     2101 aaattttgaa cagttgagac gaacttatgt gaaaacaagt tctaattgcc aactattatt
     2161 agaagtttct tgacgattat gatatgaaaa tgatcaatta tgatgtggca ttgttattga
     2221 ataaaaagaa tagtaaaatt taacgtggtt tatcttggtt agttgtaggt aaattaatta
     2281 atatatagaa ggtagataga tgaataaaaa caataaaact ttatttaatc cttacgtggg
     2341 cgtaatcatt gtttttctcc tttttagtta ttttgcttat caaggttatc aaaaggacaa
     2401 aatcgctgaa aaagtagatg atgtaacaaa aacaatccat attcaggaac aggctaaaac
     2461 ctatcaagat aatttaacca gtttaacgga tatttctaag agacaactga ttactaatca
     2521 aaaacaggca ttagaaaagg atctcaaagg tgaaattgct ggaaaacttg ttttttcttc
     2581 tacaggattt attctccctg tttttcaagg agcgaatagc gacacgctta gtttaggagt
     2641 agcttctact tattatccag atgctgaaat gggaaatgga aattatattc ttgctggtta
     2701 taacgtagat acaccaagcg ttttattatc cgatatgatt gatttatccg aaggagaaga
     2761 aattgatcta atcgatgctc attacaagta tcagtatgaa gtctccaaaa gaggaaaaat
     2821 ttatgattac agccaggtag ttcaatctaa ggaaaacaat tcctttttat ccttgccaaa
     2881 agcaggtaaa aaaccactac tcacactgtt agactttgaa gcaaataata tgaaaaagtg
     2941 cgatgtgatc cagtgcgaat tagtcaatgt agaaaaaatc aataaataag ggaagtgagt
     3001 cacattcaag aacttgtaga aaaattgatc aataaaatga gtgccatttt tctgttactg
     3061 ttggtatcca ttctttattt aatatggacg gtggggttaa atcctcctac gatattattt
     3121 atttatgata atgctgcaca gttagtgacg ttttttgtag gctgtttgtt tcttttgaat
     3181 ctgtacaagg taaagagaaa cgatctattc ttcattgcag caggcattct tttttacctt
     3241 ttcttttctt tttttagaag ctaccgagga gatactttct atggtgatct gatcgttccg
     3301 acaattattg ccattatttt gattgtaaaa tggacggaat ttactgtatt tgatcgtagc
     3361 ttgtatcttg tagtattcta tgtcttttta ctcgtaacgg tttatcgagt atttaccgag
     3421 ataccagtac cagaaggaca aagtatttgg aatccatcga acaaattatc agatatttgg
     3481 atcaatacaa atacgatagg tagttcttta atgacattag cccttcttat cacaggattt
     3541 gctagttcat ttggaaaatg gtacatgcga ttgctatcat taccagcgtt gattcttgct
     3601 ggggcaacga tttgggtttg ccaatcgaaa gcagcattat acgcgcttgt tatcttcgtt
     3661 atcctagaaa ttttacctaa gaagatcttt cgaaacacac acttgtcctt ttggatgtat
     3721 gcagcagttt cggttctagc tttaccgatt tcttattttg ctgcaatgtc agacaaagtt
     3781 catttattta caggacgaga agaaatttgg cgcaaattct atgaaacatt aggcgaaaaa
     3841 acaggacaaa tatttgtagg gatgaaacct ttctttttcc atagaggaaa tcagattcta
     3901 ggtaaccata atacgtatca cgcactcgtc aatcactatg gattgattgg ttttgctcta
     3961 tcgatgattc ttttgcttag tttcttatgg ttgctcgtaa gaaaatgtga gctgacaaat
     4021 ggacaactaa cattcttgtg ggctttttta gcgatcatgt gtcaatcttt catggaagaa
     4081 acattagcta caatcagttg ggtaccaatt gtgttcttaa tgttagcaat ggctacacac
     4141 caatataaaa ccaccagata aatgaaatag aatagtaata agagaaaaca ctttttcgtt
     4201 gtgaaaaagt gttttttgtt ttgtctgaaa ggaggcagat ggatgaaaaa atggttattt
     4261 ggttttttag gagtcgcttt aatcgtcgtt tgcagtgtgt ttggctatgt tagctaccaa
     4321 aaacatgaag gagaggtgtt taagcaaaat atagaaaaaa agatgcccgt agatcaaatc
     4381 aatgcacatg caaagagtta taaggaggat gcaacgaacg tcaataatga tatgtctttg
     4441 gggcaaatgt tgtccataca aaaagaagca atcgaaatgg gcgtcaataa acaagtattt
     4501 gcacaaattc agattcctgc acttggttta gcattgccga tttttaaagg ggcaaatcaa
     4561 tacactttga gtcttggagc ggctacttat ttttatgaag atgctgaaat gggcaaagga
     4621 aactatgtcc tagcaggtca taacatggaa atgccaggtg ttttattttc tgatattcaa
     4681 aagttgtcat taggggaggt gatggactta gttagtaacg atggcgtcta tcgttacaag
     4741 gtaacgcgta aatttatcgt acctgggtac tttagattaa tcgatggcgt tcctgaagag
     4801 aactctttct tgtctttgcc aaagaaagga gagaaaccct tattaacgtt gtttacttgt
     4861 gtctatacgt cacaaggaaa agaaagatac gtggtacagg gagagctaca ataacaaggt
     4921 tttaatcaac gcgagtcgtt gaaatatgaa atgaggagag taaaaatggc aataaatcga
     4981 tatgtaaaaa aagctggaat gcttgttgga atgttaggaa tcattgcaag ctgctttcag
     5041 gggtatcaag cacatgcaga agatgtcacg caaaaaacgc caccagagaa ggtcaatatc
     5101 acggttcata aattaatgta cgatcaaagt acgcaattga atgttgatat tgacgggatc
     5161 aaaaatgatg gttatacgca cgatcagtat cctacaggtg taacgaaata caacaaggca
     5221 gattatggtg atgttgagtt tacgttagga aatattacgg atcaagtatt accgactgaa
     5281 gattctgatc taaccaacgc gaaagtggac gaaatcgtga aagacgtaga agacaaggga
     5341 tctaacagtg agtacgtcaa gaatgcaacc aataaaatta cttcagctgt agatgaaaat
     5401 ggtgagatta cttttgcgga tcaaccagcg tacgtgaact caaaaggaaa tgtgtatgtt
     5461 atttacgaga gtaagtccgc agcaggatta gtaactcaaa aagcaaaacc aatggtggtc
     5521 attgctccaa tgactgacaa cacaggttca ggttttttaa aagacattca cttatatcct
     5581 aaaaatattg tttctaagtt gagttttgaa ttaaccaaat tcggtgatga tggtacagag
     5641 caaagcaaac aaacccctct taaaggcgct aaattcgaat tgtataaagg agaacctgga
     5701 aaaggaagca aactaggcga tcttgtttcg gatgatcaag gaaagctgac tgctactgat
     5761 ttgacgttag gaaaatacta ttttgtggaa gttccttcag aagtcgtagt gggatcagat
     5821 aaagaaccaa cagccgatca atatttatta ggcgcagacg ctcgcaacga tgcgcacaat
     5881 aaattaacct ttgaaattac gaatgatggc gtgacaagtg acttaaaagc ttcatacgta
     5941 aactataaag caccagtgat cgataaaaca gtaacaaatg gaacaggaca agaacattct
     6001 ttccaagttg gtgatgccgt taattatcaa ggaacgattc atatcccaac agacattgca
     6061 ggcggagcag acggtatcac agtaaacggc gtgaaaagcg aaacttctcc ttacagtgta
     6121 tttaaatggg gggatacagc aggacaagga ctttcttatg tcgctgctaa agcaaatatc
     6181 aaagtaacaa ataaagatgg atcagtggta ttaaaagaaa atacagatta taagatccaa
     6241 aattcagaaa atggctttgt gatcgatttt atcgtaaata atggccaagt aagtgatact
     6301 gtagcaagtt tacacggaca agatcttcaa atgacttata acatgtatgt aaatgacagc
     6361 gcagctgttg ccaatccatt aacaaatagc gtggatttcg tttataacaa caatccattt
     6421 aatcaggaag aacaccacga aaaaacgaaa gctgacgttg tgacttatgg cgcgaaattc
     6481 ttaaaagtcg atagcggact atttggaaca ggaattaagg caactcctct tgaaggcgca
     6541 gaatttgcag ctaagaatgc agaaggtaag tactacggtg gacttactga tacagataaa
     6601 gatggtgtca aagaagcagt atgggtagac gatgtagcaa atgcagcaat cctaaaatca
     6661 gataaagagg gtcattttga aatcactggt ttaactgaag gagattactc actggaagaa
     6721 acaaaagctc ctgaaaacta tcaaaaatta acaaaagaga tctctttcaa agtagacaaa
     6781 gattcataca aagaagaaaa ccgaatcacg atcaaaaata atcaaaaagc ttccgtacca
     6841 atgactggta gcaacggttt ccaatcttac gtattgatct cttgcttgtt gcttggggca
     6901 ggcgcaattt ctgcagttgt ttactttaag aagaaagcct agaaggatca gctaatgatt
     6961 atcagacacc ctaagaaaaa gcgaatcatg ggtaaatgga tcattgcttt ctggttactt
     7021 tcagctgttg gtgtcttact tttgatgcct gctgaagcga gcgtggcgaa ataccaacaa
     7081 aatcagcaga ttgccgcaat cgatcgaaca ggaacggcag cagaaacgga ttcttctttg
     7141 gatgtttcta agattgagtt aggcgatcct gttggtattc ttacaattcc aagtatttct
     7201 ttaaaactac caatttatga cggaacttcc gacaaaattt tagagaatgg tgtagggatt
     7261 acggaaggaa ctggcgatat tacaggagga aacggtaaaa atcctttaat cgcagggcac
     7321 agtggacttt ataaagataa tcttttcgat gatttgcctt cagttaaaaa gggagaaaag
     7381 ttttatatca aagttgatgg tgagcagcac gcttatcaaa tcgatcggat tgaggaagtg
     7441 caaaaagacg aactacaaag aaactttgtc acttacttag aaccaaatcc caatgaagat
     7501 cgagtaacgc taatgacatg tacgcctaag gggatcaaca cacaccgttt cctagtgtat
     7561 gggaagcgag taacctttac aaaatcagaa ttaaaagatg aagaaaataa gaaacaaaaa
     7621 ttatcttgga aatggctttt aggaagtact gtttttcttt cagtcatgat cattggttcg
     7681 ctatttgttt ataaaaagaa aaaataaagg agggtaacca acatgagaaa tagaaaatgg
     7741 ctatttgttt gtgcagccgc tcttttttct ttcactgcct acacacagtt gacgtttgca
     7801 gacagtcaag aaagcacgga tagcacagaa caaacaatcc aaacgtcaga tagcagcacg
     7861 attcaaagca gcgatgaaac cgtcgattcg tcaacagtgg attcttcaga agaaccgaaa
     7921 attgctgaag acgatcaaat agtcaaacag accattcacg ttcaaaagat tatttcttca
     7981 gaacaattag acaaccaggg gcatgaaaaa caagaaggag taaatggcgc gaagttttct
     8041 gtttatgatg tatcggacat tttacaaaag atggatgtta aggatctcac tactgaccaa
     8101 attgaatccc aattaaaaga tcgagtgaaa aaactatcca gtgatcaatt gaagctagtt
     8161 tctaatggag aaacaaagac aattgatcaa caaacaggtg tctttgaatt ctcggtagaa
     8221 gtacaggcaa atcagaaaca agcttattat attgtcaatg aatcaagtcc tgaaaacatt
     8281 tctaatagcg aggatatttt gctattaaca cctgtttctg aaaaaaacgg tgaattctta
     8341 aaggatgtgt ggatttatcc taaatcagaa gcttcgcaac ctaaagaaga agtaaaaaaa
     8401 atcgtttcta ctggtgtaaa gaaaaacttc tttgagaatt gttgggattt tgttactcac
     8461 ttgttttcta gagattaagg aagaaataag atgaaactga tcaaattatt attattcaat
     8521 ctttcttgtt taaccgcagt ctttttgtac tgcggtttat tattttctca attatctatt
     8581 ttgccaagct accaactata cctaatgagg attttaaaca taccagctgc ttccatgccg
     8641 ctagatatta tggaaaagct cattaggaat ccattattta ctacgatcaa tttgatcgtt
     8701 attgtcggaa tttcactagt catttataaa aaagagggga tgaagggatg aattttaaac
     8761 actcgtggac cagacggtta aaatatgttt ttcccataat gatgatgtta ggtacattgt
     8821 ttgggttaaa aacagccaat gtctttgctg aaaaagttat tgtcgatccg tcaaatccaa
     8881 tccagaacgt aaagaataat tttattattc caaaagatgt tcctaatgca aaaacaaata
     8941 ttactgtaaa cggagcgtcc aaagtttaca aatatcatgt tgatgccaac aaaggtggtt
     9001 ttacagacga ctacgtagga ttagtggagg gaaacaaaaa tatacgctat ccttctttcc
     9061 aaaaggaata cggtgaaaca aaccttgttt tagaaggcgt aacaaccaac accaaagtca
     9121 atattgacta tggaaaaatc ggtacgtata acgggaaaaa agtcaatatc aagctagttc
     9181 tatctaatat tcacttatac tcggatacgt tgccgtggaa tctactagat aacaactata
     9241 caaaaactca ttttcgagac gatggctata aaaatacgaa tggtgcaatg agtaaatcta
     9301 aaaaaagaac agtactttgg atctcagaca atcttttctc aggaattgtt taccattcaa
     9361 cacaaatgaa tgtgcagcta gtagccacat atgaggacgg tagccccgtt caattttcag
     9421 gagatacatt tatcagtttt aactctttga accctgcagg aggaaaaagc acggatctta
     9481 aaggagaata tgcccactat gacaaaatga atacgacaga ttggtatgtc agacaagatg
     9541 cggttctttc agaatttaaa tctttctaca acaatctgaa cgtggtaggt ggccacccag
     9601 gaggaagctc taagctgaca caagcggata atgatttcaa taatttgcat gataaattag
     9661 gagatccgaa gtttggtcaa ggtactgtat cctttaaaat atctgaagca aatccgacgt
     9721 ttgtgattgg ttcttctaat gttcaaacct ggtttacttt atcttctgcg acaatcttta
     9781 gtgttgttcc tgatcaacct gaaaaaacag gggttgataa aaatggaaat aacgtgaacg
     9841 ataaaatgtt gcaagtagga gacacgattc aatatcgaat caaacagaag gtgaatcgat
     9901 taggagtgga tttactagcg gtttacgatc gatttgagtt aatcgataat ttaccaaaag
     9961 aagtagatta cgtcgatgca cacgttgaaa gtggtacaaa taaaaaattc gatgtatctg
    10021 gtgaagtgac ctatgacaaa acaaaacacc aggtaaaata tgcagcgaaa gctgatacat
    10081 taaaaaatcg aatgaagtat aacggcgaaa cttacgaatt agtgatcaat gtaaaagtca
    10141 atgaattggc caatcaaaat agtgtagcca aaaatcaggg aacgtcgatc attaataaag
    10201 tagaaaagga tacaaatatc attaccgttt atttccctaa aattccagtg aaagaagtac
    10261 aacaaaatgg aaaagatgta aacggacgaa atgacggtaa gaagggtacg ccgacagctc
    10321 ctttaaacgc aggatctgaa gtacaatatc tagtcacaca aaaatggcac acaaaaggcg
    10381 tagacgctgc gtcagatcac tacaaacaat ttagtattca agatccaatt gaagctcgtt
    10441 tgacatataa agaaggttct gcgcaagtaa tagataagag taaaggaaaa gatattactt
    10501 ctgaaggcac actaacctat gatagcaatt caagaacgct gaagtgggaa gcttccgctg
    10561 acttcttaag taacaatctt ttagatggac gagaaattca gctgatattt acagctaaaa
    10621 ctccattaca atcagaaaaa aatattgata accaagccgt agtagcagta gataatgttt
    10681 ctaataaaac aaatgttgtg acaattgggg ttgatcctaa cttgccacag gtcattgttc
    10741 ctaaaacagg ttctacacat ttagtaacga tttcagcggt cagcttacta ttacttgtgt
    10801 tagcaacttt tagttatgcg gttctgagat acatttaaaa taaaaaaacg aaagaatgaa
    10861 taaaatgaaa aagttaataa tagtagttac ttccttgatt gccatgattg ttattttagt
    10921 cggatgtagt aatgaaaaaa ataaacaaac taatcaagat aatggcgtat tgaaatcagg
    10981 aactatgtgg aaagaagaag taggtggtct tgtttataat ttgaaaatta tagacgagac
    11041 tacctgggaa tactctgaga gtgtatggca tccagatcct gtacaaataa cagtcaagag
    11101 gcaaaaagac tataaaggtt tagaaagata caaaatagta gattcagctg gtgttaggga
    11161 atttataaac aaatctgatt ctttatttat tgttgttccc tatgagaaga atggcgtaaa
    11221 aaaaataatt tttcttggat ctagcaagga tgaaaagcga acgaaagaga aattgattca
    11281 cgatggatca caatccaata aatataagtt acaaaagact agcgagtgat tgctagtctt
    11341 tttatttgtc ctgaaggagg aatcacagtg gcaaaagcta aaacgccatt tgaaaaagcc
    11401 gcgtctaaaa tcttagaacg ccgcggtgta tctgaaacac agtggaaaca agaagtcctt
    11461 gaaaaagcac aatttgacct attacgggga aaagacaagg acttagaagg atatatctat
    11521 caacgtgaac gtgaaaagct tgttttcgat gaaattatta aacactaaaa ggagcgaaca
    11581 attttatgtt tgaatcaatt acaatgaatt ttttaacaca accgaaagta gtagctgcgg
    11641 ttgatatttt tagagcatta caaactgccg caactagttt aaaaaacaat ctgatgattt
    11701 ttgctgctgc tgcggccgtt gcttccattg ttattggggg tcttttcttc ctatttggac
    11761 gaagaggagc tgaaaatggg aagatgcacg taggctatgt attgatgggg gtaggagtta
    11821 ttttagcagc agcttctatt gtggtttcgt tatttggatt gtttggacaa acacctcaag
    11881 gattataaga aagtaaaaaa gtaggagtaa gaagtagtcg atacttttta ctcctttttt
    11941 atgaaaggag aatactcatg tactttacga ttgcaggcaa taccaaaaca gataaagagt
    12001 taataaaaaa agcaacgaag gaagtaggaa agcgtacttc ttttttaccg aaaacaatta
    12061 aatattctgt cattgaaacg gaagaacagc tacatgtgtt agggaaagta ctggaacacg
    12121 aaagtcgatc ttctgttaag ttgactctca cgttacatga cacagaagga aaaatagaga
    12181 aagctggtac agaatacgtt tttggcccac tggattatca aatttcagaa ggtttctatc
    12241 ctacattgat ggatttaatc cgccttgatg tgtttaaaga aacggatgaa actatgagtg
    12301 tggaagagtc ttatcgaaac gaaaaacttt tacaagtttt agaagaagag ttagagagcg
    12361 accaaagaaa agtgaatcaa gggagtgaag tcgaagtaaa tgaagaagta ccatgggaac
    12421 gaccaatatt tccaaagaag gagtcaaaag aaaaagagac agtctatgtt gacgaacaag
    12481 ctgatattcc gactcagaaa tcgatatttg aggaagagaa cgatgtgatg ggtcaattgg
    12541 aggtagatcc ctttgaagaa acaatggagg atgaagagac ggccgaagta gaagttgatc
    12601 cagttgaagc gaatgaagag tcaacatgga ctgaagggga ttctcaggaa tatattgaac
    12661 cacttatcag tgaagaagta gaaaaaaacg aaatagagat acaaaaggca actgtatttg
    12721 attatatttt ggatcaatat ccgccagagc atgaatggat gaaagaaaaa aacaaattat
    12781 ttttaaatga gctttattcg aaatatcaat taccccaaac ctatcaagca tttttagaga
    12841 gtaaagaaga attaatctca cagggtaaag gcacactttt agaacagtta gagtctgtcc
    12901 aatcaacaaa ttggcatgag cttgcacaag aagatttatt agccaccttt gaagaacgtc
    12961 aacaagaaac agatcaagaa attaatgagt atgcgacgga acagtcgtct aattgggaga
    13021 aagcaaaaga ggaactaaat aaagaagaac agcgagtgat tgaagaagaa gtacaaaaaa
    13081 ttaaagagcg
//
LOCUS       DASHWW010000075        13013 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.075, whole genome shotgun sequence.
ACCESSION   DASHWW010000075 DASHWW010000000
VERSION     DASHWW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.075"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(112..1692)
                     /locus_tag="U2R64_002370"
     CDS             complement(112..1692)
                     /locus_tag="U2R64_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEM8919157.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLYQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2093..3469)
                     /locus_tag="U2R64_002371"
     CDS             complement(2093..3469)
                     /locus_tag="U2R64_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEM8919158.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3597..4715)
                     /locus_tag="U2R64_002372"
     CDS             complement(3597..4715)
                     /locus_tag="U2R64_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8919159.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4857..5291
                     /locus_tag="U2R64_002373"
     CDS             4857..5291
                     /locus_tag="U2R64_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8919160.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5369..5902)
                     /locus_tag="U2R64_002374"
     CDS             complement(5369..5902)
                     /locus_tag="U2R64_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEM8919161.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(5996..7174)
                     /gene="mutY"
                     /locus_tag="U2R64_002375"
     CDS             complement(5996..7174)
                     /gene="mutY"
                     /locus_tag="U2R64_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEM8919162.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7167..7964)
                     /gene="recX"
                     /locus_tag="U2R64_002376"
     CDS             complement(7167..7964)
                     /gene="recX"
                     /locus_tag="U2R64_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEM8919163.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8071..9453
                     /gene="rlmD"
                     /locus_tag="U2R64_002377"
     CDS             8071..9453
                     /gene="rlmD"
                     /locus_tag="U2R64_002377"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEM8919164.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9627..10205)
                     /locus_tag="U2R64_002378"
     CDS             complement(9627..10205)
                     /locus_tag="U2R64_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HEM8919165.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10527..10997
                     /locus_tag="U2R64_002379"
     CDS             10527..10997
                     /locus_tag="U2R64_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HEM8919166.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11105..12331)
                     /locus_tag="U2R64_002380"
     CDS             complement(11105..12331)
                     /locus_tag="U2R64_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8919167.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3844 a         2628 c         2185 g         4356 t
ORIGIN      
        1 aattctacct tagatgttct tatctcactc tatcagtcct atttgacaaa gagccgtttt
       61 tgtttggcta ttcttattac ttgatgcagg gcagcttgtg tcaagacttc tttacatcaa
      121 actttttaat tttacattgg gatatttatc cgcaaaccag cgttctgcaa attggttctc
      181 gaataagaac aacggttggt cgaaacggtc acgagccaag atattgcgac ttgaactcat
      241 cttctcatcc aaatcttctg gatcgatcca gcgagcgatt ttgtgtccca ttggagacat
      301 gattacttcg gcgttatact catttaacat acgatattgg aatacttcga attgtagctg
      361 accaacagct ccaatgatat attcttccgt tagatatgtt ttataaagct gaatcgctcc
      421 ttcttgaact aattgataga ttcctttgtg gaaggatttt tgtttcatga cattttttgc
      481 agtcactttc ataaacagct ctggagtaaa tgaagggagt tcttcataag caacttttag
      541 ttttccttcg aacaatgtat ccccaatctg ataattgcct gtatcatata caccgatgat
      601 atcgcctgct actgcttttt cgacgttttc tctcgaatct gccataaatt gtgtgacatt
      661 gcttaatttc agttttttat ttgtacgttc caaccagaca tccattcctc gttcgaatgt
      721 tccagaacag attcggacaa aagcgattcg gtcacgatgg gctggattca tatttgcttg
      781 gatcttgaat acgaaacctg aaaattcttc ctcataagga cttaccatct gatcatcttg
      841 tgttttgtgt ccataaggag ctggtgccaa ttcaacgaaa gtctctaaaa aagtctgtac
      901 accgaagtta gtcaatgcag aaccaaaaaa tactggtgtc tgatcgccac gagcaatttt
      961 ttcttgatta aatgcatctc cagcctcttt gattagttct acttcttcta agacttgttc
     1021 atataaggaa ttttcagtta gaggatgatt ttcgggaagc agtccatctt catccaattc
     1081 tactaatcgt tcatcctgat aattttccgg acgataaaac tctacacgat tatggtagat
     1141 atcataaaga ccttctagcc ctttacccat accgattggc caattcatcg gataagattc
     1201 gatatctaat agctcttcta attcttctaa caattccaat ggttcacgac catcacgatc
     1261 tagtttgttg ataaaagtaa atatcgggat gccacgtttt tttacaactt ggtataattt
     1321 ctttgtctgt gcttcgatcc cttttgcact atcgattacc atgaccgcac tatccacggc
     1381 catcaaagta cgataagtat cttcagaaaa atcttcatgt cctggtgtat ccaagatatt
     1441 tactcgtttc ccttgataat caaactgcat aacagaacta gtaacagaaa tcccacgttg
     1501 tttctcgatt tccatccagt ctgatttggc aaaattacct gtttttttgc cttttacggt
     1561 cccggcttga cggatagccc caccaaacaa tagtaattgt tctgtaatcg ttgttttccc
     1621 agcatccgga tgggaaatga tcgcaaaagt tctgcgattg tccacttgtt gctttaattt
     1681 tggattattc ataacctaac tccatttctt ccattcaatt atttatattt tctctaggca
     1741 cagattgtcc gatctcttaa agaaagacaa tttcatatag ggctgtgaca aaagccgtgt
     1801 agcagtctct ttttccgagt aaacggcgtt ctagagacag cctatcagca ataagcccac
     1861 ccaagccaaa aatacgaaaa gctgtttttg cttggctgct cttattactt aatgcaggat
     1921 agctttttca caacctttgt caactactac aactgaatca gtatagcatg gattcagcga
     1981 atgaaaaagc caccaaacca taagagtcaa atattttttt gtcagctgac taaaagaaaa
     2041 gacgtgttgc ttgtttattc aagcaacacg tctttcataa ccaagtttcc aattatcttc
     2101 ttggctcgtc atcttcgaat tcttttctga agtatcttcg ttcttcttca ggttccgctt
     2161 ctgtttcttc cggatcatga aaaatgacac ggattttaag gattcgagaa ccttccattt
     2221 cttcagaaac cagcgtaata ttatcgacat caaacgataa cttttcgcct tcatccggaa
     2281 tcatgcctaa tgctgtaatc aaataaccag ccatcgtatc tacatcactc atatgcagat
     2341 cactgtcaaa agcttcattg aactcatcaa tcagcatacg tccttggatg atatattcgt
     2401 gttcatcgat tttttcataa agattctcaa cttcatctga ttcatcatcg atttctccga
     2461 cgatttcttc taaaaggtct tctagtgttg ctaacccaac gacgccgcca tattcatcta
     2521 ataaaatagc catctgattc tgcgtctttt tcatttcata taacagatca tcaataaaga
     2581 ccgtttcagg aacgaataaa ggctcctgca tgattttctt gatatctaaa ttatcaaagc
     2641 cgaatttatg ggcagctttt agtaaattct ttgtatgaag gattccgact actttatctt
     2701 tgtcttcgtt ataaacaggg attcttgaat agttttcgga taaaacttca ttcacatttt
     2761 cttccacagt gtcgttgata tcaatcataa atgcatccgt tcgtgggacc atgacttctc
     2821 gggcaacttt cgtatcaaga gaaaaaaccc cttggagcat ttctaattct tcattattca
     2881 atacgccttc gttttcaagc atataacgca tttcatctct ggtcattttt gaatcttcat
     2941 catcaaaagt catcggcgtg atacgcgcca ataaacttgt ggaagcagaa agcagccaga
     3001 cgaagggctt agctactaca ccaatcaagc gtatcagccc tgaagtgaac tttgcgactt
     3061 cttctgattt atttaaagca atacgtttag ggtacaattc tccaaaaaca atcgatacat
     3121 aggtcaaaat agccagcaca atgatatttg caatattttt tgccgctgtg ccgccaccta
     3181 ataccggagc taaccgttcc gataaagtat tagctagtga agcaccagac aaaatgttga
     3241 ccaaagtgat tcctacttgg attgtcgata ggaaattatt tggattctgc aatattttta
     3301 aaagcttttg agatttcaca tctccttcat cagctttttg ctcgattcga ttcttattga
     3361 tcgaaacaac agcaatttcg gaagctgcta aaaaagcatt gatcaatgtc aaaacgatca
     3421 ataataaaat ctgcgctaac agcgactgac tctcagggtc agcattcata atcgcattct
     3481 ctccttataa aattaatttt tagtttacga tagaaaaaaa cgtggcacta tagccacgtt
     3541 aaaatggtat cacaaagcaa ttttctttgc aataaaaaca agtgtactaa aactacctac
     3601 gaggtcgtag caattttctt cttgttttca ttttgcttgt cttctttgac gattttgatt
     3661 atataggaaa tgatcgtctt gcagattgcg taaaaaggaa cacctaagaa gataccaagc
     3721 aatccggcaa tatttccagc tactagaaga acgataatga tcgttaatgg atggattttc
     3781 agtgatttcc caattacatt aggataaatg atattcccat ccaactgttg gacgattagc
     3841 acaaccacac aacaaagtaa tgcttttacc ggatcattga agactgttac tagaaatgca
     3901 ggtgctagtc ctagataagg tcctaaatat ggaattaggt ttgtcaatcc cgcaatgacc
     3961 ccaaataaga aagcataatc cacaccaatt accatatatc ctaaaaatgt gaaggtacca
     4021 acgaataaac attcgattgc ttgtccgcta atgtaattag ccaatgtttt attcagttgc
     4081 cccaataact ccacaatttg gtttcttctt ttttctggga aaaactgttg gatgtttggc
     4141 actagttttt ctccgtcttt caacatatag aacaagatga atggtgctgt aatgattact
     4201 acggttgccg aagcgatcgt tccaacgatc gaacctaaac tattggatac tccactaagg
     4261 aattgctgaa tgattgtccc gtaagaaatg tctaattgct caaaatattt attgatatct
     4321 acttccttga acaaaggcaa ttcggctacc tcttttaacc agctttctac ctgtttgatg
     4381 aaatcaggca tattagatgc caatgaggaa atttgctgta ctagacttgg gatgacacta
     4441 agtaaaatcc aaataattgc tgcaactaaa aggagcagca caattgcgac agcccatatt
     4501 cttttgattt ttgctttcat caacagcttg acaataggat tcaataaata gtaaagaaag
     4561 cctgcaatca gtacaggtgc aaataacgtg gaaaaaaatg tcccgatcgg ttcgaaaata
     4621 aagtttattt ctgatgaaat catgatcaat gcagctatga tcaataattc aagcgaccaa
     4681 aacattagtt tagactgtct aagtttttca aacaatagat ttcctccttt ctttcttact
     4741 agtatatatt atattcgtta aaaattcttt tattcttttt ttatttttga aaacttgcca
     4801 tactttttat ttgttttatt ttccagtata ctatacgaaa ggaaggtggc tagaccatga
     4861 aagttgtaca aacaaaagat acaatgagca atatttactt agatgctgta cggatcaggc
     4921 atcaagtttt tgtagtcgaa cagggtgtgc ctttgtctcg agaaatagac aaagatgaag
     4981 cccattgtat ccacttcgtc ctgtactcag ataaaaaaga accgcaagga actgtacgtc
     5041 ttttgccttt agaaaacgga aaaatgaaat tacagcggat ggcgattctt tctgaataca
     5101 gacaccaagg gttaggaaaa atattgattg aagaagcaga aaactttgct aagaatcaag
     5161 gctataatac gattttatta ggggcacagt ccacagctga aactttttac gaaaaactag
     5221 gatatacagc ttacggcgat ccttttgaag atgctggcat gcctcatatt tatatgaaaa
     5281 agactttata aaaatttatt tcgaaaaaag caaaaaacag caagcttttg agaaaaatct
     5341 ctcactggct tactgttctt ttttgtgttt acttacgcga caattgcttg taacggttat
     5401 accaaatatc aatatagcct tccgagaacg ggccatctcc attattgatc cagtcaacca
     5461 gaatcttcac attttctttt aggatgaagt caatatcgtt cgggtaattc atcattttgc
     5521 tgtgcatctc atattcatcg acatccaata gtcgtttctc gccgtcagga aataccttga
     5581 tatccaagtc atagtcgata tatttcaagg cctcatcgtc cagcaaaaaa ggtgaagcta
     5641 gattacaata ataggaaacc cccttttctc tgatcattgc tattacattg aaccagtatt
     5701 ttttatgaaa ataaacaatc gctggttcgc gcgttaccca tcggcgtcca tcagattcag
     5761 tgactaatgt gtgatcattc acgccgatca tagagtgttc gcttgttttt aataccatgg
     5821 tatctcgcca cgttcgatgc aatttgccgt cgtgcttgta actttggatc gtcacaaact
     5881 ctccttcttt tggaactccc atagcaaccc ttccttaagc agcattttgt gctttgtgtt
     5941 tgggtgttca ttacaccgac atcataatta ttatatcaat aaaaatgagc tttgcctaga
     6001 aaggattcct attgtttcga tttttctcta actgatctac cagtttcatt tggaccttag
     6061 gaaaaacgac cgaatcaaat gcatcaggct tcaaccactt cgaagttttg ttctcggtaa
     6121 attcttgttc tgctccctcg gttgcccgtc cgtaaaaaag gagaacatgc catttcagat
     6181 gactaaaaat atgagtaact tctcctaaat gtcgtgtctg ccaaacaaag agttcctgct
     6241 tttcaaatgg gagattttgc tcttcttctg ctactaggtc atcaaacaga tcgatttctg
     6301 gctttgtttc ccattctttt ttcaatcgct catactcctc ttgtgtcact tccatcattg
     6361 gaaatgtcca catattcgcc agcaattttt ggctatctct ttcttcaaaa taatacgctc
     6421 cagaatgatt ttgaagagct gcactgatat aataaacgtc ttttggcttt gctttttttg
     6481 tttttacagg aaaactcgtt tggattcctc gtttgttagc taaacaaaag gcttggatcg
     6541 gacaagtctc acactttgga gaagttggtg tacagatagc tgaacctaga tccatcattg
     6601 cttggttgaa ttcacctgga tgcttttcat caatgatttt ccgcatcgct tcatcaaaga
     6661 ttttcctgct agaagctttt gcgatgtctg cttcaatgca aaacaatctg ctgactactc
     6721 gcatcacgtt gccgtcaact gcaggttctg gaagtccaaa tgcgatactt gcaatcgcgc
     6781 ctgtcgtata tggtcctatt cccttcaatg agctaatttc ttcaggcgtt tgcggcattt
     6841 ccccatcaaa ttctgacatg atctgtttag cagcagcttg gatgttccgg gctcttgagt
     6901 aataaccaag gccctcccat gcttttaaaa gcttttcttc tggagcattt gctagctctt
     6961 caattgtagg aaaccattcc atgaaacgat aaaaataatc gatcactgtg tctactctgg
     7021 tttgctgaag catgatctca gagatccaga tacgataagg atcacgatta tagcgccaag
     7081 gcaggtttct tttttcttgt tcataccatt gaatgaactg atcttgaaat tcttttgttt
     7141 ctttatctgt ccatttttcc cattctttat tcactttcct cttccttttc cgtaatgaat
     7201 cgctggatca tatccaaatc aaatcctttt tgatataagc tttgctttac ttttagattt
     7261 ctttttttag gttcaaacct taaatttctt cgccatagtt tatctccttg tttgactaaa
     7321 taatcatatt ctatttcttg atctgcttct tgcggaagat cagctatcgc ttgttggatc
     7381 acttcttgag aaaagccttt cgtcatcaat gtttgttgga tttttctcaa taattctttt
     7441 tggctttttc cgtgattttt tccaaacgct ttttcggctg tctgatgtgc attttgaact
     7501 tggtcttcaa atgtatattg gctgagcgct tgttcaatga tttcaggttt caaacctttt
     7561 tgctgcatct gctgcgctaa tttctttggt cctttgtcac ttaagcgcat attcgtgcgc
     7621 acataacttt ccccatagac caaatcatcg acaaggtcca attcttttaa gcgggctacg
     7681 attttatttc gatcttcttg aaggatttcc ttttctttta agtatgttcg gatttctttt
     7741 tccgatcgca actgataact taagtaattc attgctaggt gaaaaccgaa atcagctccg
     7801 ctactcttct tgatctcttg gatagtttct tcgtctaatt cccgtccttt taataatcga
     7861 tagcgtacta atacatcttc agatacttgt aaagcttctc cttcagataa atctacgcga
     7921 tagaaagggc ctttgccttt actgattctc gtaacggtta acataaacat cctcctcgaa
     7981 catatattct ctatcatacc acagaaaatc cccgtaatca ggtattatat gttagaataa
     8041 accacagaaa aaagaaaaag ggagatactt atggcagaaa caattgtcaa aactggacaa
     8101 acggttcctt tgaaaatcaa gcgtttaggc ataaatggtg aaggaatcgg ttatttcaaa
     8161 cggttgatca tatttgttcc atatgcacta ccaaaagaag aagtactagt gaaaatcacg
     8221 aaagcaactc ctcgctatgc agaaggagaa ttaataaaag tcaaaaaaac aagcaaagat
     8281 cgcgtagtgg caccatgtcc tgtttactat gaatgcggtg gctgtcaatt acaacactta
     8341 gcttatcaag ctcaattgga ttttaaaaag gatctgcttt tgcaagcatt ggaaaaattc
     8401 aaaccagcag gctttcgatc ttatcaactt ttgccgacga tcgggatgga tgagccttgg
     8461 cattatagaa acaaagcaca atttcagtta cgaaaaaata agcagactca aaaaattgaa
     8521 gctggtttat acgaagcaaa ctctcatcag ttagtcccta taacagactg cttggttcaa
     8581 gaacctcgaa cacaaaaagt aatgaatact gttgttcaac tattgaataa atttgatgca
     8641 cccatctatg atgaacggac aaacagtgga atcttccgca caatcatggt tagaatcggt
     8701 gttaaaactg gggagttaca agttgttttt attactcgca gtaaaaaatt cccgcaaaaa
     8761 aacgcaatga tccgtgagat caatgaacga ctgcccgaag ttgtttcaat catgcaaaat
     8821 gtccaggcac aaaaaacgtc tctcgtgatg ggggatgaaa cgatccactt atggggaaaa
     8881 gaagccattg aagaacaaat caatgaagtg actttcgatc tttctcctcg tgccttcttt
     8941 caactcaatc ctcagcagac cgaattgctt tatggcgaag gaatcaaagc attagatgtc
     9001 cagcctaatg aaacgatcgt ggatgcttat tgcggagttg ggacgatcgg cttaagtgta
     9061 gcaaaacaag ccaaagaagt acggggaatg gataccgttc ctcaagcaat cgctgatgca
     9121 aaaaaaaatg cggaaagatt aggatatcac aacactcgat atgaagtcgg gacagcagag
     9181 caagttctgc ctaaatggtt gaatgaaggt tttcagcctg atggtatcat cgtagatcca
     9241 ccacgtacgg gtttggataa cgcattgatc caatcattat tgaaataccc tccaaaaaaa
     9301 cttgtttata tctcctgtaa tgtttctaca cttgccagag atctggttaa tttaagtaaa
     9361 aagttcaaga ttgaatattt acagtccgtc gacatgtttc ctcagactgc acgttgtgaa
     9421 gttgtcgtga agatgacgag actcgctgac taaatgaaag aggttgtgaa aaagtctgcc
     9481 ctgtatcaag taataagaac agccaaacaa aaatagctct tcatgtttta tgaatactgt
     9541 acttgtgacc gaagagttaa caggaggaca ctatttattt aaaaaaaggg ttgtgacata
     9601 gtttttgtca cagccctttt tgattattat tggatattca cgtctatcac ttgataaaat
     9661 gcatttgtcg tatcgctgat attccatact gctaaaatca cattatatcc ttttcgatcc
     9721 tgcggaagtg tgatcgtttg gttgactgtt tttggtggaa cagttgcttt gtcgtctatt
     9781 tttgtgatca attcaaaatc actaaatttc aaaggttgat taggattcca agttggtttg
     9841 gtaatgtagt aatcccaagt acttgtccga tgttgtgctg ttaaattcca agtaatattt
     9901 aatgttcctg gattaaccat gtttttatgc catctgttag atgtctgttc atctaaaggc
     9961 tcaaagccgc tgactcctgc actagcaatt tttccatcaa tgaatgtatt tttggtagct
    10021 tcgatacttt gcggttccca ttgtgctctt ccgacatttt gatttaagtt tcctgctgct
    10081 gatgttccta ggtatgcacg gcttcctgga gaagtaatat aaccatgcgc aaaacctgga
    10141 atgctaaaac cgaacaaccc taaactaact aacccaataa acaataacgt actaatcttt
    10201 ttcatgtaga aacctccttc atttgataac cacattgtaa acgctttatt gtattaacac
    10261 aaacattatg cttttataat tttatgttga agtaaaaaag gtgaaaaaag taagatgcag
    10321 attataacag aagtagacga gaaaagtaca aatagaaaac atgagaatca aatcatatga
    10381 tctttttcaa aaacatcatt catataaaca aatgttcaac tttttaataa caacaattat
    10441 caattttttt cttacttcac aaactaaata caggtcttgc tgtgagcctt catggtaaac
    10501 taatattata gaaaggagtt agtaaaatga agatgataaa agatattcgt ttttgggttt
    10561 gtgttatagg aattgtcata ttaggctttt tatcagggtt gcttagcgga aatcccggaa
    10621 aatattacta ttctttgcaa cttccaccat ttgcaccacc tagctggata tttgggccga
    10681 tgtggacctt actgtatata ttgatgggta tttctcttta tttgttactt aatcacaaca
    10741 acaaaaaaca gcgaaacaat cttgtcggtc tttttgtgat tcagttcatt tttaatttta
    10801 tatggtctgc tctatttttt aatttaagaa atattttcat tgcagcaatc gatattacac
    10861 ttttagttat tttcttgtca gtgcttatgt atcagttgtg gctgcatcat cgcctggcaa
    10921 tgtggctcat gattccttat tatttatggg tactattcgc aactctattg aattattcaa
    10981 tttatttttt aaactaagcg ctaaaaagag acgtcctgta atttaacaca tagaaaaagt
    11041 gccacctaag ttagattttt tgtctaattt aggtggcact ctttattaac caaactattt
    11101 ttttctagta cccacttgtt gttccatact cattattctg gtcataacca taaccatttt
    11161 gttcctgtcc agcgtaagga tcataacttt gagtatcttg acttggtgta tagtactgac
    11221 ttgtatcttc tgtttgctga taataggtat tcggatcttg gtactgatca tatgtgtttt
    11281 ctgaatagga agaataatcg gtgtaccctt cactattcga tccatcaccg tttgtcgaat
    11341 cgccatcttc cgaatcatca aagaacatca ttgaagcatt ctcatttttc aaattaggta
    11401 atgtatcgct tgtttttata tttaattgtt tcttcagttc attttggatc gaaagaagat
    11461 cattttttcc taaaatttga tagtagatat cattgatcat ttgtccttcg ccttgcaact
    11521 ggtcttgttt gattgtttca aacgccgggg tgtagttcgt cgctacatca agcatgtcat
    11581 cccaatctaa gtccgtcgtc acattgttct caactgcttt taaaattttt ctataattgc
    11641 ttacgccatc taaacttaaa actttattga cgattttcgt cactacttcc cgctgacgac
    11701 gttgtcgacc gatatcgcct tctggatctt cgtgtcgcat tcgagaatag gctaaacctt
    11761 tttctccatt caatgtttgt tcacctactg gtacatggac accatccaaa gtaaagtcaa
    11821 ttttattatt cactttgatg ccaccgaccg cattgatcaa atcttccatg ccatccaaat
    11881 tgatcgttac ataatgatca ataggaatat cgagcagttg ctcaattgaa tccatggcca
    11941 tttcgacacc accaaatgcg taggcatgat ttaatttatc taccgttcca taacctacga
    12001 tattcgtata aatatctcgg tccaaactga tgatcgttga ttttttttgt ttcggattaa
    12061 ctgttactac catcatcgta tcagaacgtc cttgttccgt tcttcctaat ccaccggtat
    12121 ctaaacctaa tagcaaaacc gaaaaaggtt ctttgtcatc aatgcttact ctctcagaac
    12181 gtttggagga tattcgatta gagtttttag aaattttgtt tactgtttgg ctcgcttctc
    12241 ccataaatct gattccgtat gctgataatc cggcaatcag caaaacgaat acccctaaca
    12301 aggttaatag aactttttgc catcgcttca taatacacct ctgtttcaca ttttctaaaa
    12361 tattgtctca tataactgtt caatcagcaa attcactttt taatcataag aaaactttaa
    12421 aaaacatttt tgtgtaacga ttattatttt ttaaaatttc tcaaaattct taactatcat
    12481 accataccgt gaaaaagatc gaaagaccga atacacgcag ttcgcaatcg ttttatcttt
    12541 ttttatgtat tttttccaga aaaagcgaac aacaaggtat tttccaaata atcgtgcagt
    12601 aaaatgatcg cacatacctt tcccatcttt ttaacagtct ttgcctaccg ttcagattat
    12661 cattcgattt cacgacaatt tcttcctatg actggtcctt ttgttaaacc catcttctat
    12721 tcgttttatt tccagctcac tgcatggctc ttaaaatgac tcgaactagt gattgcatta
    12781 ccatcatctt ttaatggata gatatgctcc tcttcaaagt aaaacgattt tcttttaaag
    12841 taatagaatt gacatggtaa tgagtatgta tactagtggt ttcacaaatg gtcttttatt
    12901 caacatccaa aaactgaaat ttctttaaaa tccattacta acgaagaaaa tgttccttgc
    12961 ttgataatta gttaggacat gtcaagtgaa caaatgcatt tacttagcca aaa
//
LOCUS       DASHWW010000076        12596 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.076, whole genome shotgun sequence.
ACCESSION   DASHWW010000076 DASHWW010000000
VERSION     DASHWW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.076"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(10..159)
                     /locus_tag="U2R64_002381"
     CDS             complement(10..159)
                     /locus_tag="U2R64_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919168.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="U2R64_002382"
     CDS             555..755
                     /locus_tag="U2R64_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8919169.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="U2R64_002383"
     CDS             1323..1886
                     /locus_tag="U2R64_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919170.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="U2R64_002384"
     CDS             complement(1947..2291)
                     /locus_tag="U2R64_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919171.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="U2R64_002385"
     CDS             complement(2388..2633)
                     /locus_tag="U2R64_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8919172.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="U2R64_002386"
     CDS             complement(2703..2957)
                     /locus_tag="U2R64_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919173.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="U2R64_002387"
     CDS             complement(3121..3444)
                     /locus_tag="U2R64_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919174.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="U2R64_002388"
     tRNA            3631..3704
                     /locus_tag="U2R64_002388"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="U2R64_002389"
     CDS             complement(4089..4586)
                     /locus_tag="U2R64_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8919175.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="U2R64_002390"
     CDS             complement(4626..5435)
                     /locus_tag="U2R64_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8919176.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="U2R64_002391"
     CDS             5769..6626
                     /locus_tag="U2R64_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEM8919177.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="U2R64_002392"
     CDS             6619..7521
                     /locus_tag="U2R64_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEM8919178.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="U2R64_002393"
     CDS             7554..7904
                     /locus_tag="U2R64_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEM8919179.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8876
                     /locus_tag="U2R64_002394"
     CDS             7953..8876
                     /locus_tag="U2R64_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEM8919180.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8954..9847
                     /locus_tag="U2R64_002395"
     CDS             8954..9847
                     /locus_tag="U2R64_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8919181.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9885..10448
                     /gene="amaP"
                     /locus_tag="U2R64_002396"
     CDS             9885..10448
                     /gene="amaP"
                     /locus_tag="U2R64_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEM8919182.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10462..10650
                     /locus_tag="U2R64_002397"
     CDS             10462..10650
                     /locus_tag="U2R64_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEM8919183.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10663..11565
                     /locus_tag="U2R64_002398"
     CDS             10663..11565
                     /locus_tag="U2R64_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8919184.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11597..11839
                     /locus_tag="U2R64_002399"
     CDS             11597..11839
                     /locus_tag="U2R64_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8919185.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12095..12466)
                     /locus_tag="U2R64_002400"
     CDS             complement(12095..12466)
                     /locus_tag="U2R64_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919186.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4462 a         2113 c         2364 g         3657 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatattct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gattgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 tatggaattc tgaaactttc atcaaacgtt tagacgatga acagctactc tatgatgtcc
     8581 atttgagaca gcgacaaaca gaaaaaatga tcgagatcta tcgagattta ttagagagta
     8641 ttggtgatct attcaacggg atgatggaca ataatctaaa tcatatcatg aaatatctag
     8701 attcagctgc attaatcatt tccgttccgg cgttgttcgc agggatttgg ggaatgaata
     8761 caggaggatt accgggtaaa agttctgctc taggctttat actcgtagtc tttggctctt
     8821 tgatagcagc agtagtttta ggttaccatt tataccggaa agattataca aattaaagaa
     8881 tctatttaaa acaggtatca aacaaagaaa tttgttttgg caatacaatt taaaaactag
     8941 gaggaataca gcaatgacag aaccaaaatt aatcgacccg cgaaacttgt accatacgga
     9001 gaaatttcct aaacaagatc aggatacacc agctttacag cagaatatga ttcctgttcc
     9061 tgattgtgga gaagaatcct atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat
     9121 cactggtgga gattcaggga tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc
     9181 agatatcgct cttcaattct tcccaggaga agaaaaagat gcagaggaag tagcaaaata
     9241 cgtgaaagtt gcaggacgta agattgtctt actacctttt gatcttcgtg acgaacaagc
     9301 acctaaagaa atcatagata aagccgtgag tgaacttggc gggctagata cgatggtact
     9361 aaacgcagga cagcaaattt cttgtcagtc tattgctgag ttaccacttg agcaagtcaa
     9421 agacacattt atgataaaca tcatcgctat gtttgcttta gtgaaagaag ctgttccgca
     9481 tatcccagca ggaggagcaa tcgtaacaac aacttctgtt caagcattca atccaagcga
     9541 acatttatta gattacgcag caacaaaagc ttcaatcgct aactttacga tcggtttagc
     9601 aaaacagctt gcacctaaag gaatccgtgt aaatggtgta gcacctggtc caatctggac
     9661 accattacaa ctagacgaag gacaaccttc tgattcgatc cctgaatttg gtcagcaaag
     9721 tttactagaa cgtgcaggtc agccaggaga attagcacca gtttatgttt tcttagcatc
     9781 gaataaagca agttatgtta cagcccaaat ttacggagta actggtggag aagcgatcaa
     9841 cttataagaa gttgatcgtt tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa
     9901 aaacgatcgg agtgatcgga acattacttt tgctatctgt gcttttgttt gcgatactat
     9961 taagtgcaac ctatccattg ccttttcagc tagagaagtt tcgattcttt tccatcacta
    10021 attcatacgt gcaacaatat gtattttggc ttgccgttgc atttgctatt ttgacaatta
    10081 tcacgttact tgttttcctg ttttatccaa aaacaatcgg aaactttcta ctgaaacatg
    10141 gtgatgggga gttgacgttg gataaaaaag caattgaagg aatggttcgt tctcacttgc
    10201 atgaagatga attcatccat tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg
    10261 ccgtcaatgt aaaaggggag ttgaaacgaa cttcagcact cattggtaaa acaggaacat
    10321 tgatgaaaga aatcgaaaat gaagtacaac acatattggg aacaaaagag ccagtgaaag
    10381 tatcggtgaa atacacaggc tttgaagaac cagctaaacg aagcaatgac cgcaaacgag
    10441 tagaataggg ggggaccaaa aatgaaagaa ctattttcga catacaagct ccctatcatc
    10501 tttggggtac ttggattgat attagccgtt ttatggatca ccgtgggctt tttcaagacc
    10561 ttattgatct tgatcatggc agcgatcggc gtcgctatcg gtttttatct gaaacaaacg
    10621 aaaatcttag atcactattt taaatcttag gaggaaacat ccatgaataa caataacaaa
    10681 aataataaca ataaaatgaa caaccaaaaa ccagtgtctg cacatccaga cccaacgaca
    10741 ccaaaccaat caaatggtgt gaacgatgaa aagaacaaaa cagcaccagt atctgcacat
    10801 ccagatccag tagtccctaa cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa
    10861 aagcatgcac ctcatcatcc aggaactcca gaatctaaag ttccagaaca acatgatgca
    10921 atcgatcctt ctaaacctgt ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa
    10981 gaaaaactta gttctgacca cacaaacgga caaggaaaac ttggttctga tcatacaaat
    11041 aaccaaggaa agcatgattc tgaacaggaa gattcaatgc gcggtgagct gaattatgaa
    11101 gataaagttg tgcaaaaaat catcggaatc gcaattgaac aagtagacgg tttattatct
    11161 gcaaacggtg gtttcttctc taatgtggca ggaaaacttg tgaatacaga taatgtaacg
    11221 gctgggatcg aaacagaagt cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg
    11281 gaatatggca aagatatcga aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa
    11341 gtaaaaaata tgacacattt agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa
    11401 acaaaagaag aatttgaaaa agatcaagaa acggtgcaag acaaagtaac tgacgcagcg
    11461 aaaaaaaccg gtgaatttgc ttcgaatcaa acagataaag taaaatcagc agctggaagc
    11521 ggcgcacaaa aagtaaaaga aaatacagaa ccacgggttc agtaataagg aagtaaaaca
    11581 ttaggaggaa cgaaacatgg gatttatttg gtcacttatc gtcggaggaa ttatcggagc
    11641 aattgcagga gcaatcacga ataaaggttc ttcgatgggg attattgcaa atgtcgtagc
    11701 aggtttagtt ggatcagcac ttggtcaagc attattaggt tcttggggac caagtattgc
    11761 aggaatggca atcgtgccat cattgattgg tgccatcatt ttagtactaa tcgtatcatt
    11821 ctttgctcga aaactgtaaa aagactttta aaaagaggtc gtgaaaaagc tgttcttcat
    11881 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcatttg gttgggcata
    11941 ttatcgaaga tgcaagcttt tgaacactgt ttatacggaa taagaggctg tgacaagact
    12001 tttgtcacag cctcttattt atgcgggcaa attcccaatt agatttttaa aagtttttcc
    12061 ttaaatgtgt ctttattgat acagagaagc ttctttaata aaacaatgcc tccctaaatt
    12121 ttcttgagat aggaaaggtg aacatacaaa ataatacgac cactttgaaa acccagatga
    12181 tccacaaatg gatcgtatga tactgatgaa gtaaaaagca atggatcaga aactcaaaga
    12241 gattgaaaaa gacaaggaag aaataatatc tcttttttac tcttgtctgt tttagccaat
    12301 aatagctcgt aaagtaatct agacaaacaa atagaagtaa acaaagtttc gtaagagcag
    12361 caatcgtatc atgttgctct gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa
    12421 tatagatcac gagtaatgaa agaaaaaagt aaacaataaa tggcatacta ttcctcctaa
    12481 ttgtgtgagt tcgccctcat tttaaaataa cgatatttgt ttgtgaagct ttttcgtgtc
    12541 gtaacaaatg ttatctaatg tatttttaaa taaataatca ttattatcaa aataat
//
LOCUS       DASHWW010000077        12156 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.077, whole genome shotgun sequence.
ACCESSION   DASHWW010000077 DASHWW010000000
VERSION     DASHWW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.077"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            474..725
                     /locus_tag="U2R64_002401"
     CDS             474..725
                     /locus_tag="U2R64_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919187.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
     gene            759..1037
                     /locus_tag="U2R64_002402"
     CDS             759..1037
                     /locus_tag="U2R64_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919188.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            1634..1891
                     /locus_tag="U2R64_002403"
     CDS             1634..1891
                     /locus_tag="U2R64_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919189.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            2004..2615
                     /locus_tag="U2R64_002404"
     CDS             2004..2615
                     /locus_tag="U2R64_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919190.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSARYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            2794..3351
                     /locus_tag="U2R64_002405"
     CDS             2794..3351
                     /locus_tag="U2R64_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919191.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(4050..4571)
                     /locus_tag="U2R64_002406"
     CDS             complement(4050..4571)
                     /locus_tag="U2R64_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEM8919192.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            4770..8462
                     /gene="nifJ"
                     /locus_tag="U2R64_002407"
     CDS             4770..8462
                     /gene="nifJ"
                     /locus_tag="U2R64_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HEM8919193.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            8651..9538
                     /locus_tag="U2R64_002408"
     CDS             8651..9538
                     /locus_tag="U2R64_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEM8919194.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            9535..10704
                     /locus_tag="U2R64_002409"
     CDS             9535..10704
                     /locus_tag="U2R64_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919195.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            10728..12083
                     /locus_tag="U2R64_002410"
     CDS             10728..12083
                     /locus_tag="U2R64_002410"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEM8919196.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
BASE COUNT         4044 a         2041 c         2669 g         3402 t
ORIGIN      
        1 acaaataatt ggtttattct ggcaggcgta atgctttttt ctagtttcta tttatttagt
       61 aatgctctat tagcacagcg agggaaatat aagtttaaaa tattagatta gatattattt
      121 ttagagggga taaatataaa atgaaaagag gttatttata atggaaaaag tattaccaat
      181 taagagctac tgtattccaa ggcttttcat catagaattt caaaagtaaa gacatgtgtt
      241 tcacaaatag tgtctatcct ggctaaataa ttcttccact atctgcttta atttcagtag
      301 acttttcggc aagttatttg ctaatgagat gaatagagat tacaactcgc ctataaccgc
      361 ttaaaacaag cttttttaaa gtatagttag caagtcgtat tcatatgttc aaagaggagg
      421 gcttatgaac tttgaattca ttccgtgtga acagaacagt agggggaagt aaaatgaaag
      481 aaaagcctat aaataaatgg tcattgtata aaaattcaat gtttggagtt gttatctttg
      541 gtgtttgtgc tggattattc cttttcatat tattacaaac ggtgactctt ttctcttcta
      601 atcctactta tggatggaga gacagtatag ccttagggat gtttgcggga ggatatggat
      661 tcttattgtt gttctcaatt ctcacactaa gtccaatcca tggactcatt caactttgga
      721 agtaagaacg agccttaaac ttttcgttct cggaagaaat ggaaaaacac aacataacag
      781 gcagtatgta tgtggatgat caatggttta tcagcactga tgaggtaaaa atagctgcca
      841 ttaggagaga ttacctgcag aaaattcata aaataaaaga tcctaatggg aaaaaggcaa
      901 ggttaattat aactttgata acatctaatg gtaagaagtt aaaacttgca ggatcatatg
      961 ataatgttaa aaagttcgaa cattggtatc tgcaaaaaga cagcattagt cttaataaac
     1021 aatttgaaaa aaattaatca aagtcatcgg caacacgaat aatttgacat cttgatattg
     1081 tgatataagc aaaaacggca tttctgagac cgaacagcat aaaaaattta aatgttggaa
     1141 tttatataag caaaacccaa gaagctagat gcgatagagc atttaatttc ttggggtttt
     1201 gcttgggaat cagcatatca attaaaatga tcatctcggt atttcaaaag tgggtacgat
     1261 tacaaatagt tggagcaaaa tagtgggtaa aattaccatt ccagtgtctg tcttgcctct
     1321 ttttcgtcaa tcacaaatag acgagattca taggaaaaat cgatacaggg tatgatttca
     1381 atgatattat gaccaattac aaaatagatt gataaagcat tttttgcatt tttataatag
     1441 tttattgata ataatgtatg agatacagta taatgattta aaaggtaacg tgttgtgacc
     1501 gaattaaatg aattaatgcc tattttttat attccttagt ggacaaaaat ggagacagtg
     1561 aagttaggag cattgtatcc tttgttgcgt agttcaaaaa agtaagcgat ttctataatg
     1621 gtcagggtaa acggtgaggg ctgtccacgt aaatcctact attgaaatca caatgatcgg
     1681 acattcaaaa ggtggtgctg aagcagcaaa ttcagtagct ataaatacga atgcgattat
     1741 atttaatcca gcgacagtaa atttatctgc ttatgaatta gactcaaaca catatacagc
     1801 aaacatggta gcttatgttg tcgagggaga tgcattaaat gttgtttttg gaggagtata
     1861 cacctattgg agaattaatc atgttagata gacaatatga tgcaccttag tggagaatga
     1921 tatctcgcat aggtaactca gtaaaaaatc aaggtatgga agcaattatc tctgcattgg
     1981 aagatcgata tagataggcg gatatgaata gtaatagggg gaataaaatg gaatacaatg
     2041 gatcaatgag aattgtacaa attatatttt ggattacatc gggaattgtg atcataggag
     2101 gagttttttt gatgttgcca agcttaatat ttcctttctt tgcattaatc tcacctaaaa
     2161 tacccgaacc ggaaatcacc tatggagaat ttccatttag gattgaatac gaactagatg
     2221 gacagattaa cataattgaa gatactgtca tagctgagtt taacgggtgt gagttcagcg
     2281 caggttctat gaaaagagaa cgaagatgga gaagtagatt agctagtggt agagaagatc
     2341 taccttttgg ggacgatcta ggaatctatt ttagtcgagg aagtgcgcga tattatatgg
     2401 gggaaaatgt acaatcaatg tcattaaaac cacatatagc ccttagaaat ctcgaggaag
     2461 gttttaaaag agaggtagac tttatattag gagaaagtgg atacataaga actgtactta
     2521 atttcggaga agcgcaagaa gttttgacac aatacggaat taccttaatc aactgggaaa
     2581 tatctgaacc gattgttaac aattttggtg attagaaaac aattacgata aatagaaaca
     2641 agccaaatca tcagcaagta aaagctgatg atttggcctt tcttatacga gtagtaggaa
     2701 ttcatagcga atattattac gaccagtaga tattttgata ttaaaggagt attacgaact
     2761 aatatgtgag aatgtagagg tgatgtgcga ataatgagaa atttatcaaa tagaaacaaa
     2821 atattaatca ttattgttgt tatagctgtg tttcatctgg gaacgaatgc ggttttaagt
     2881 agaataatat tgggtcctaa gccaccaaga ccagaaatta cccgagggga gtttgatttt
     2941 agattagaat atgaagtaga tggggaaagg attgtgatag aagatacaat tgttgcatta
     3001 tttgatggat tttctgcaga tgcaggtagc atggcatggt atcgcacgtg gcgtctacat
     3061 ttagcaagtg atagacgatc acgaaatatc ttattagatg aattagagga tggtcgaaga
     3121 atatattatg tcccagaaag tgctaactat tctatgggag atgtacagaa aaaaagagag
     3181 cctaatccta attggtatcc atttaatggc gtaacaatag aatatccacg caataaaaca
     3241 cctgaaatag gtgcaaaatt tataagtggt ttagaagatc tgtacgatag gtttggaatc
     3301 cgtcttatta gttgggaaca cgatccacca atagaaaatc gctttgaata atcgaaatct
     3361 actaatccat ttcatcagcc agtgaatgtt gtaatggaac aatttggttt agtgttcaaa
     3421 accattgaaa tactaggctg tgatcagcaa aaatgaatct gaataaaaaa gagagcaact
     3481 attagctgag aggagttaat agttgttagc tttatacgaa tcaaagtggc aaatacagat
     3541 gcgtatgcat ttgtgtttgc catcttgcgt ttggtagacg agataggtat aagctaaaga
     3601 aacaacttgt ttaaaataaa cgacctagct caacaaatga ccatctaatc aactaacagc
     3661 atacataaaa gcaactattt ttgaagtaga attgaaatcg ggataactta aaaagtgatt
     3721 gggatactag tgagaatcac cgtacataaa tattactcgt taagggaaat tgagaaattt
     3781 tgtatgaaaa tttaagaatt agttagtatg cgcaagtcaa aaatatgaat aaattatttg
     3841 gtggagataa tttgcttagc ttgtcataag aaatgagata atctggcaga tgcaagcttt
     3901 tggacaccat ttattcggaa taaggaggct gggacagaag cgtttaactc caagaaataa
     3961 gaaggagttg cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc
     4021 tttacttttg tcccacgctc cttatttttt tattttgttt ggatcaattc ttttaattcc
     4081 tctattgaaa tagattcatc aaagatttct ttacccaaga tgacagttgg aacaaatcga
     4141 atatgtgctt gctcagcttc gttgatgaca gcttggctca gctgttcgtc tttttgttct
     4201 gtcagcttta gtttatctac tgcaaaatcc gctacttctt ggagagaaag atgtttccac
     4261 tcgtcttgag tatcgaatat ttgtttgatc tctttgatcg ctttttggcc atcgctgatt
     4321 gtgagatacc ggtgcatcac gttccctcgc tgtaagcttt ctttttcttt atcgaacaat
     4381 ttgatcactc gctgcaattg cccgctttgg actgcttctt ctaatagctc ataagattct
     4441 tcaaaccatt gtcggcaata cggacaagct aagttgatga attcgaccat ttttttagga
     4501 gcattcgatg aaccataaag gattcctttt tgtgtatttg ttttcgttgc atcaatcact
     4561 gatatatcca tgttaaaaca cctctttcgc ttatagttta tacatgtctg acaaaaaaag
     4621 gcaacgattt agactgtttg tctaaaaatt agatgaccaa ttcaaataga tacatgtaaa
     4681 atatttttat aaataaaaga aaaaaatggc atgttttacg ttataatgga acagataata
     4741 agagagaata tgaacaagga tgatgaatca tgcgaaaaat gaaaacaatg gatggcaata
     4801 cggcagccgc atatatttct tatgcattta ccgagattgc tgcaatatat ccaataacac
     4861 ccagttcgac catggctgaa ttagtagatc aatggtcagc agcaggaaaa gaaaacgtat
     4921 tcggtcaacc agtaaaagta gtagaaatgc aatccgaagc aggagcagct ggtgtggtcc
     4981 atggatcatt gaaaactggt gcactgacaa ctacatatac cgcttcacaa gggctgcttt
     5041 tgatgatacc gaatatgtac aagattgctg gggaactact gccaagtgtt ttccacgttg
     5101 ctagtcgggc agtgacgaca aatgcgttga atattttcgg agatcacgga gacgtgatgg
     5161 ctgcaagaca aacaggattt gctatgttag ctgaaagcag tgtacaagaa gtgatggatt
     5221 tagcacctgt tgcccatctt gcttctattg aaggagaagt cccttttttg aatttctttg
     5281 atggattccg tacgagtcac gagattcaaa aaatcgaagt tttggaatat gaagaattag
     5341 ctcctctgat caatcaggag aaattagctt catttcgtaa acgagggatg aatcccaatc
     5401 atccgactgt tagtggtacg aaccagaatc cagacatcca ttttcaacaa cgggaaacga
     5461 tcaaccccta ttatgataaa ttacctgaaa tcgttcaaaa atatatgaaa gagatcaacc
     5521 gattacgagg aacttcttat gacttggtga cttattacgg agcagacgat gcggaagaag
     5581 tcattgtttc tatgggatca gttgcacaga cgattgaaca aacgattgat tacttgaatg
     5641 caaacggacg gaaaacaggt tttttgaata tccatcttta tcgtcctttt ccagtggaaa
     5701 cattcgtgca aaagttgcct catacagtaa aaacaattgc tgttcttgat cgaagtaaag
     5761 aaccaggggc aggtggagaa cctctcttat tagacgttca aagtgcgtta tatgattctg
     5821 aacttcgccc ggctgttatt ggtggtcgct acggattggg gtctaaagat gtgactcccg
     5881 accaaatctc agcagttttt gatgaattga aaaaagaccc aagcatacgc aaaaaacggt
     5941 ttaccatagg gatcgtggat gatgtgactt atcaatcttt ggaaccaaag gaaagtctgg
     6001 atttgacaga accgcaaaca ttccaggcca agttttgggg atttggatct gacggaacag
     6061 ttggagcaaa taaatcagct atcaagatta ttggagatca caccgataaa tatgcgcaag
     6121 gctattttta ttatgattcg aaaaaatctg gcggtctgac tgtctctcat cttcgttttg
     6181 gagatacgcc gatacgttca gcgtatcttg tcgagcatgc ggaccttgtt gcctgtcaca
     6241 caccagctta cctgcatagc tatgacttgg tcaaaggatt gaagccaggt ggcatttttt
     6301 tattgaatac tctttggagc gacgaacaat tagaaacgca tctgccctta aaattaaaac
     6361 gttacttggc tgaaaataac attagattct atacgatcaa tgccatgaga ttggcccaag
     6421 aagtcggttt gggacgccgg atcaatacgg caatggaaac ggcttttttt aaattagctg
     6481 acatcattcc ttttgatgag gtgcttccgc tgctaaaaga agaagccctg aaaagctatg
     6541 gacataaatc aatggctatc gtagaaaaaa acatacaagc aatcgatcgg acgaccgaac
     6601 tgcttcatca agtcgcgatc ccagaccatt ggagaacgtt ggagatgcct gaaaaaatca
     6661 ataaaaggaa cactggttat atacaagaaa tacttgaacc agtgaatgca caggaaggaa
     6721 atcaactctc tgttggtaca cttgtagcaa atggaatgac aactggcgaa atgcctttag
     6781 gaacggcttc tatggaaaag cggggcgtcg ctttagaagt acctgagtgg attagtgatc
     6841 gctgtacgat gtgtaatgaa tgtgcctttg tttgtcctca tgctgccatc cgtccatttt
     6901 tagcagatga agaggaaatg gaagaagcgc cagaaggatt tatcgtgaga gaaatgcgag
     6961 gcgcagacgg cgtaaaatac cgtatccaag tttcagtgga agactgtaca ggttgtggtc
     7021 tgtgtgtaga ggcttgtccc gcaaaagaaa aagctttagt gatgaagcct tatgaagaac
     7081 agaaagaaca agctgtgaat tgggcttttg caatgacatt aagacaaaaa gcaaatccag
     7141 tcaaaggaaa gaatactgtc ttgtctacac aattcaatca accgcttctt gaattctcgg
     7201 gcgcttgctc aggctgtggc gaaacacctt atgtaaaatt attgacacaa atgttcggtg
     7261 atcgaatgat gatcgcgaat gcgacaggct gttcttctat ttggggcggt gcttctcctg
     7321 cttctcctta tacgaccaat gaatgtggtc aagggcctgc atggtcaaat tctttattgg
     7381 aagataatgc tgaatttggt tatggtatgc ttctagcggc acagactcgt cgcgaggctt
     7441 tggcaagttc aatcaaagaa gtattgccaa aagtatcaga agaactacga gaattgatgg
     7501 aagactggtt agtacacatg tttgagagtg aaggaacgca gcaaagagca gcaaaactgc
     7561 aagctgcgat cgaaagcgaa cgatcaattt tccctgaact ggaggatata tacaagagaa
     7621 aggatctatt cgtaaaaaac agccaatgga tgattggtgg agacggatgg gcttacgaca
     7681 ttggttttgg cgggatcgat catgtacttg ccagcggagc agacgtgaat atccttgttt
     7741 tggataacga agtctattcc aatactggcg gtcaaacctc aaaagcaaca ccagcttcgg
     7801 caatcgctaa attttcggct agtggaaagt atgcttcaaa gaaagatcta ggaatgatgg
     7861 cgatgacata tggaaatgtt tatgtggcgc aaattgcttc aggtgccaat caaatgcaaa
     7921 cgatcaaggc atttgaagaa gcagaaaagt atcctggtcc ttctctgatt attgcctata
     7981 cgccttgtat cacacatggc ttgcttggcg gaatgaaaga atcgcttaaa gaagcaaaag
     8041 aagctgtttc ttctggttat tggtcattat atcgatataa ccctacaatg gtcgaaaaaa
     8101 acaagaaccc aatgactttg gactacaaaa aacctgattt ctctgctatg cctgatttca
     8161 tgaggaaaca agttcgcttt tcctcgctag ataacgcaaa tccaaatctt gcaaaagctt
     8221 tatttgaaaa gactgtccac gacgctaaaa cacgttttta caactatgct gcactgacgg
     8281 gagaattaga aaaaatcaag aaacgacttg aaccagagga atctatcgat gtacccgtta
     8341 agactagaaa agaaaaaacg acggaccttg aagcagaaga aagaagagct gctagaagag
     8401 ctgccagagc agaacgacgt aaaaaaatgg aacaagctac aaaagaaaaa aaggaaaaat
     8461 aacagaaaaa atataatgaa taattctctg aagtttaaaa atatttattg cagagaaaaa
     8521 taaaacgcat acttgcaatt ttcttgaaaa ttatgcgttt ttctcaagaa aaatacgagc
     8581 atatcagcct ctaaaattaa aacatatgat atactagaga ggaaatctca aaagagaaga
     8641 gaggcttttt atgtcatttc aaatcgggga actttttaat ttggactatt ggcagcaaat
     8701 gttttccggt gacttgttct ctctgaattt tttggtgaac atacttgata ttctggttgt
     8761 ctggtatctt gtatacaaac tgatccaact gctgcgaggc acaaaagcga ttcagcttct
     8821 gaaaggtgta gctattttta ttgttatccg aatcgtagcg gaaatcattg gtctgcacac
     8881 cttgtcttgg ctgatgaacc aagtcattac gtacggggtg atagctgcta tcgtgatttt
     8941 tcagccggaa atccggagag gactggaaca tcttggacgc agttcgcttt tcaaacaatc
     9001 aaaaagcgaa cagcaggaag atgagaagat gatcttgtct tttgacaaag ccatccaata
     9061 tatgtccaag cgaaaaatcg gtgcgttgat cactatcgaa cgtcatactg gattagatga
     9121 gtatattgag acagggattg ctttagatgc agatatcact ggggagctgc tgatcaatat
     9181 ctttattcct aatacaccgc tgcatgacgg tgcagttatt gtaaaagaag gaaagatcgc
     9241 agtagcaagc gcctatcttc ctctatcaga aagtatgttg atccctaaag aattcgggac
     9301 tcgacaccgg gcagctgtcg gtataagcga agtcagtgac gcgattacca tcgttgtctc
     9361 tgaagaaacc ggggacgtca gcatcacgtt agataatgaa ctgatggctg gcttatccca
     9421 gcaagaatat ttggcaatct tgcgtagaga actaattgct gaagagaaaa caaaaaacaa
     9481 gaaaaacgtg attcaatctt tcctagacgg tatgactaag ggaggggatc gcaaatgatc
     9541 tcaaaagaga aacggacaag cattctttac agttttattg cattgctgtt cagtattgcg
     9601 ctgtacttca atgcaaatgg ccagtccgtt ccaaatacgc tttctggaaa tgaagcgtat
     9661 aatcaaacag ttacgggggt gccgatcaag atttcttatg attcaaagcg ctactatatc
     9721 catggatatg aaaatgcagt gactgtcaaa ctttccagtg caaaccgagt tcagttgaat
     9781 gcagaggcaa acgaagatac acggatgttc cgcgtcacag cagatatcac taagctgggc
     9841 gaaggaacac atgaagttcc gctaaaaatt caaaatttga gcagtgctgt cacagcaaag
     9901 atcgaaccat cgactattac agtaacggtt gagaaaaagg taataaaaga tttcgatgtg
     9961 gaaacgttga ttccttcaac gttcacacca tctggatatg aacttgatga tacttccgtt
    10021 agtcctaaaa aagtctctat cactacaggt gacaaaacat tggcagaaat caaacgagta
    10081 gtagctgatg tggacgcttc gatggtcaca gatgatggga ttaatagtga ggtcccaata
    10141 caggcgctga atgcagcagg ggaagtatta agtatcgtct ctgatccagt gcaagtaaca
    10201 gtgagagctg attcgatcaa gccaagcaag tcggtacgac tttatgggat acagcaagga
    10261 acaccagctg ccggggtaga aagctatgat ttcagttttt caaaactgga agcagaagta
    10321 agcggctcta gcgatttgct tgcatcgatc ggtgacagta ttgctgtacc gatcaatgtc
    10381 tcaggtatca atcatcgaac aactcgtaaa attgaaatac cagtagaaga ggggttaagt
    10441 atcaagcccg aatcagttag tgtggagatt acacccgtgt tgcaaacgtc aagcagtagc
    10501 tctgcttcga cgagcagtcg gacacaagaa aatacaagta cgagtagaag tatttcatct
    10561 gctgattcag gaacggaacc atcgacaaca accatttctt ccagttcgga atctgggaca
    10621 agcagctcga ccacaagtac agaagaaaca tcagaaacaa gcgaatcaac acaaatgagc
    10681 agaacaaatt cctcagaaaa ttaagttaaa ggagtaattt tacaactatg ggtaaatatt
    10741 ttggaacaga cggcgtacgc ggtgaagcca acaaggaact tacgccagaa cttgcattta
    10801 agctgggacg gtgcggaggt tatgtcctaa gccagcatga agaagaagga aaacgcccac
    10861 gcgtgttagt agggcgggat acaagaatct caggtcaaat gttagaagaa gcgctgattt
    10921 caggactttt atcggtgggt atcgaagtgt tccagctagg tgtgatctct acaccaggtg
    10981 ttgcttatct gacacgtttg caaaaagcaa gcgcaggggt catgatttct gcttctcata
    11041 atccagcaca agataatgga atcaaatttt tcggtgcaga tggttttaaa ctagtagatg
    11101 accaagagct agaaattgaa gcattattag atgctgaagt ggatgaattg cctcgtccat
    11161 cagctgaagg attgggaact gtagaagaat ttccagaagg cttattgaaa tattctcaat
    11221 tccttgtaca aacgatcaac ggtgaccttt ccggtttgac catttgtgtc gatgcagcaa
    11281 acggagcaac ttcaacaagt gttaatcgtt tgtttgccga tcttgaaaca gatttttata
    11341 caatgggcac aaatccagac gggttaaata tcaatgacgg cgtaggctct acccatccag
    11401 aacgtttagc tgagatggtc gttgaaaaag gagcagatgc tggactagct ttcgatggcg
    11461 atggcgatcg tattattgcg gtggatgaac ttggaaacat tgtcgacggt gataaaatca
    11521 tgtttatctg tgctaaatac ttggcagaaa aaaatcgatt gaaaaaagat acgatcgtta
    11581 cgactgtcat gagtaactta ggattccaca aagcggtgga aggaatcggt ttgaaagatg
    11641 tcgttacaca agttggtgat cgttacgttg tagaagaaat gcgcaaaaac gattataact
    11701 ttggcggcga gcagtctggg cacatgattt tcttagattt taacacaact ggagatggga
    11761 tgctttcagg aattcagtta ctgaatatca tgaaacagac aggtaagaaa ttatcagagc
    11821 ttgcagcaga ggtaacaatc tatccgcaaa aattagtgaa tatccgcgta agtgataaaa
    11881 acggtgcgat ggatgttccg gcaatcaaaa aagtgattga agaggcagaa gctgaaatgg
    11941 gatcagaagg aagaatccta gttcgtcctt ccggtacaga accattactt cgagtgatgg
    12001 cagaagcgcc tactgatgag aaagttaatt actatgtcga taaaatcgcg gcagtagtca
    12061 aagaagaaat cggactggat taagagatat tttcataaaa aataaaagaa caaggaccag
    12121 tgtcagatgt ctgacactgg tccttgttct tttatt
//
LOCUS       DASHWW010000078        11924 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.078, whole genome shotgun sequence.
ACCESSION   DASHWW010000078 DASHWW010000000
VERSION     DASHWW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.078"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..2373
                     /locus_tag="U2R64_002411"
     CDS             1..2373
                     /locus_tag="U2R64_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919197.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKAAVRELLEEA
                     VPTDFLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VREIEATPEDKKRIESGQIEVIKKTYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTLEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2434..3894
                     /locus_tag="U2R64_002412"
     CDS             2434..3894
                     /locus_tag="U2R64_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEM8919198.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGLAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQGIGGDIIELTQLFFIDDSIQNPKQRFKAALDYIIKDENKVERVEN
                     LHFETQEYKHHPIDYRPLTEKGRSYLKEQRKFPEWLIDYGEQQGLILEMKPRNERKNY
                     IVQDDRLDYAIVFPWKDRHTDQILGATYQGTIVDYERFGKRGVDKRIDINPTPNHGFN
                     VLLGSPKNLKFFESPIDLLSYAALNRETIKDTWLVSMDGLKDAVVGHYVREAVTELAP
                     KEEFPESIEICVDNDRAGHVFWDKVHRLGVSNPFTGKAVYFEPNLPNDWQVPREYQTI
                     YEEVGKEMRVAPEAIMAIHKIENNLTDTNQIVSFGEIQGVFAKKLAPKEKAQSIVVKE
                     KCIEAAQQLKSCEKSDGTYDFDRFYRGKGKINEQIQFSLKAKHYFEGYKNHEHEFVSE
                     VKKDWNDQLKHEIQQQAIRKQKRAMLFQQGRQQERE"
     gene            3905..6109
                     /gene="topB"
                     /locus_tag="U2R64_002413"
     CDS             3905..6109
                     /gene="topB"
                     /locus_tag="U2R64_002413"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEM8919199.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDEKWKQWSLAHLPIFPNQYHYHVPKDKKKQFNVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPVDLGWKKLFGK
                     ESDGKEKEEEPLLPKVAKGEMVTVDLQVLEKETKPPKPYTEGTLITAMKTAGKTVDSE
                     KAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6125..6274
                     /locus_tag="U2R64_002414"
     CDS             6125..6274
                     /locus_tag="U2R64_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919200.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6348..6941
                     /locus_tag="U2R64_002415"
     CDS             6348..6941
                     /locus_tag="U2R64_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8919201.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKEAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDEYAIQPHYTNKENFDLGITETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            6957..7856
                     /locus_tag="U2R64_002416"
     CDS             6957..7856
                     /locus_tag="U2R64_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEM8919202.1"
                     /translation="MTPTQFKAKTRNFATEKHLNPQIVQRYYMMEKLLERIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTADPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKKLYNQEMPQLMKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKVERKQNFKRSQQMNQEMER"
     gene            7859..8344
                     /gene="ssb"
                     /locus_tag="U2R64_002417"
     CDS             7859..8344
                     /gene="ssb"
                     /locus_tag="U2R64_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8919203.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTATFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            8366..8623
                     /locus_tag="U2R64_002418"
     CDS             8366..8623
                     /locus_tag="U2R64_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919204.1"
                     /translation="MAKKNSLTMDLLIPVIAFIDGISLGITENLLVNRIAKGSLFLVF
                     VYLVCSYLLKRVGKDNSFWRLTKVTIGATAVILTAILPLYM"
     gene            complement(8783..8905)
                     /locus_tag="U2R64_002419"
     CDS             complement(8783..8905)
                     /locus_tag="U2R64_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEM8919205.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            9059..9319
                     /locus_tag="U2R64_002420"
     CDS             9059..9319
                     /locus_tag="U2R64_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919206.1"
                     /translation="MEHYTGLLDKIRVIKTQPLLVRFTLHTSHEPINCVVANIEIADK
                     LLILEEGKYTISVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9762..9962
                     /locus_tag="U2R64_002421"
     CDS             9762..9962
                     /locus_tag="U2R64_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEM8919207.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PICGKKYTLSYGDYILIEEKGR"
     gene            9967..10404
                     /locus_tag="U2R64_002422"
     CDS             9967..10404
                     /locus_tag="U2R64_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919208.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10397..11104
                     /locus_tag="U2R64_002423"
     CDS             10397..11104
                     /locus_tag="U2R64_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919209.1"
                     /translation="MNNVVYQLTMEDISRFLTNKEHLNEVIRRIQKDFSCMEEMKYFV
                     QNVEEQLYLESETSQTKVTVSNNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKS
                     ELVENFISYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGIDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKQMPYQRFERKKGQ"
     gene            11485..11664
                     /locus_tag="U2R64_002424"
     CDS             11485..11664
                     /locus_tag="U2R64_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919210.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFNIPALKK"
BASE COUNT         4451 a         1990 c         2485 g         2998 t
ORIGIN      
        1 atggcagaag aaaaagaacc actagacaat agtcgtttgg gaaaatccaa aagaaaatta
       61 gtacgattgc aaaatgaatt aaacgaacaa attgaaaaga tgtttgaaca ccagagaaag
      121 accaacggtc aaccaatgaa cgataagaga aatgggcatt cttggtttag gcaacaagag
      181 cgaatcgaaa ataaagtgca tagtctgaga gaagagatca agcaacaaga aaaacaagta
      241 gaaaaacttg aaagacaaga agagataaag gaaatgggct ataacaagta cggcggactg
      301 gatatgacga tcgagaatat tccaagaatc aaagaagaaa tcgaacgctt tgaaaaaggt
      361 gaatcgactt tttcagccgc tacgatccga aaataccaac ggaaattgga aacattagaa
      421 cagctgaaag aaagatcgga aaaaggaaaa gaaaaccttc ttcctgaagt acaagcaatc
      481 attgacagcg gacgagtgac gcaatggaaa aaaaatccga ccatttattt tctgaaaggc
      541 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgtacca
      661 actgattttt tgaaggagaa agaaaacgat catttttatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
      781 caactcaaaa cgttggataa ccaatacgcc gcagaagcag gttattataa attctatttt
      841 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
      901 aacagtaatc aacccatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
      961 gaacaaaaac aatcggtcaa aaatgaacct gtttcgaaag aacaaatgca gtcgaaagaa
     1021 acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1081 aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc atactcattc tcctgaagac
     1141 gtcaaagaac ttttgaactt tatgtctcgt tttccagaac gatcctttag aaatcaatta
     1201 ttgattgagg aacaatttcc aggtgcaacg gcttgtttag gtcgtgccgc gttgaaaaaa
     1261 gaaggaatct atatcaaaaa aggggaacaa gggaacaaga tctttgtcag aaaaacggtc
     1321 aaaggatttt atgagaaagg acgtggcttt gttcgagaaa tagaagctac accagaagat
     1381 aaaaaacgaa tcgaaagtgg tcaaatcgaa gtgatcaaaa aaacttacta cacgattgaa
     1441 aaagtgtttg atatcacaca aacacagtta aaacctgaag actatccgaa aatctttccg
     1501 aaccgtgtct ttgattttca attggataaa aaaggacagt cagaacttca agctgggatt
     1561 caagcggtag ccaacaatat tggaatacaa attcgagata tgacagaaag tgaagtctat
     1621 caaagagaat taggacaagc acgtggggcg tatgttcgta acgaatttac tggcgaagaa
     1681 gaaatcgtca tgaatactcg aaatactcct acgcagcatt tagctacaag tattcatgaa
     1741 ttagcccatg caagaatgca caaattttca gaattagata ccgcaactaa agaattgcag
     1801 gcagaaatga cttcttatat tgtgtgcaaa cattttggaa tggacacgtt ggagaaagct
     1861 attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa ggaagctgcg
     1921 gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat tcaaaccatt
     1981 tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc agaagtgaag
     2041 caggagcata aaaatactgt agaaacggca gaacaaaaga atattgtgcc tgttggttca
     2101 ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg aacgttacat
     2161 ttgaaggatg cggcgtttat tgaagatcca cagcataatc aagtaatttt aaaaggaaaa
     2221 agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct aggaaattca
     2281 ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga aatctattat
     2341 gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact atctgaaaaa
     2401 cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat gagtcttatt
     2461 gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggttt agcggtagtc
     2521 aataaaggac gagactatcg tttagaagac catgattctt ttgttttcga tcgaagaaaa
     2581 cagcgatttt attggaacag tcaaggtatt ggtggggata ttattgaatt gactcaattg
     2641 ttttttattg acgattctat tcaaaaccca aagcaacgtt ttaaagcagc gctagattat
     2701 attataaagg acgaaaataa ggtggaacgg gtggaaaatc ttcactttga aacacaagaa
     2761 tataagcacc acccaattga ttatcgacca ttgacagaaa aaggacgaag ttacttaaaa
     2821 gaacaacgaa aattccctga atggttgatt gattacggag aacaacaagg gttgatcctg
     2881 gaaatgaagc cacgcaatga acgaaaaaat tatattgtgc aagatgatcg cttagactat
     2941 gcgatcgttt ttccctggaa agaccgtcat acagaccaaa tattaggggc aacttatcaa
     3001 gggactatcg tagactatga acgttttgga aaacggggtg ttgacaaacg aatagatata
     3061 aatcctacgc ctaatcacgg gtttaatgtt cttcttggat ctcctaagaa tctgaaattt
     3121 tttgagagtc ccattgattt acttagttac gctgctttaa atcgcgagac gatcaaagac
     3181 acgtggcttg tttctatgga tggactgaag gatgcagtag tggggcacta tgttcgagaa
     3241 gcggtgacag aattggcgcc gaaagaagaa tttccagaat cgattgagat ttgtgtggat
     3301 aatgatcgag ctggacacgt attctgggat aaggtacacc gacttggtgt gtcgaatcca
     3361 tttacaggaa aagcggtgta ttttgaaccg aatcttccca acgattggca agtaccgaga
     3421 gaatatcaaa caatctatga agaagtaggg aaagaaatga gagttgcgcc tgaagcaatc
     3481 atggctattc ataaaatcga aaacaaccta acggatacta accaaatcgt atcgttcggt
     3541 gaaatccagg gagtatttgc caaaaaactt gcgccaaaag agaaagccca atctattgtt
     3601 gtaaaggaaa aatgtataga agcagctcag cagctaaaat cgtgtgaaaa atctgatgga
     3661 acatacgatt ttgatcgttt ttatcgtgga aaagggaaaa ttaatgaaca aattcaattt
     3721 tcattgaagg ccaaacacta ttttgaaggt tataaaaatc atgaacacga atttgtttct
     3781 gaagtgaaaa aagattggaa tgatcaattg aagcatgaga tccagcaaca agcaatcaga
     3841 aagcaaaaac gtgcgatgtt gtttcaacaa ggcagacaac aagaaaggga gtgaaatcgt
     3901 catgatgaaa accgttattt tagcagaaaa accgtcacaa gcgaaggctt atgccgatag
     3961 cttttctaaa gctacccgaa aagacgggta ttttgaaatc caagatcggt tgtttccagg
     4021 agaaactgtg atcacgtatg gttttggtca tttagtcgag ttagattcgc ccgatatgta
     4081 cgatgaaaaa tggaaacaat ggtcattagc gcatttgcct atttttccaa atcaatacca
     4141 ctatcacgtt cctaaagata agaaaaagca gtttaatgtc gtcaaacgcc agctgcagtc
     4201 agctgatacg attgtgatcg cgactgatag cgatcgtgaa ggggagctga ttgcctggtc
     4261 aatcattcaa caagcaggcg ccaatcaagg aaaaaccttt aaaagacttt ggatcaactc
     4321 cttagaaaaa gaagccattt atcagggatt ccaacagtta cgagacgcag aagagaccta
     4381 tccaaaattt gaagaagtac aagcacgtca gatcgccgat tggttaattg ggatgaacgg
     4441 tagcccactg tatagtttac tcttgcagca aaaaggcata ccaggaagtt tttctttagg
     4501 tagagtccaa accccaacac tctatatgat ttatcaattg caggaaaaga ttagaaactt
     4561 ccaaaaagaa ccatattttg aaggaaaagc ccaagtaatc gctcaaaatg gcgcatttga
     4621 tgcgaagctt gatccaaatg aaacccaagc gacacaagaa gcatttgaag cctatttaaa
     4681 agaaaaaggt gttcaattag gaaaacagcc aggtacgatc cttcaagtcg aaacagagaa
     4741 aaaaagtgcg gctagcccac gtcttttttc tttatcgagc cttcagtcta aaatgaatca
     4801 actcatgaaa gctagtgcca aagatacttt ggaagccatg caagggttgt atgaaggaaa
     4861 atatctaagc tatccgcgaa cggatacccc ttatattacg gaaggggaat atgcgtatct
     4921 gttggatcac ttagacgaat acaagcattt tttaaaagcc gaagcgattc cgactcctat
     4981 tcatacaccg aatagtcggt atgtgaataa taagaaagtc caggaacatt acgcgatcat
     5041 tcctacaaaa acggttatga cagcagcggc ttttgaacaa ctaagtccac tgcagcaggc
     5101 tatttatgaa caagtgttaa aaacaacggt ggccatgttt gcggaaaagt atacctatga
     5161 agaaacaacg atcttgacgc aagttcagca gcttcagtta aaagcaatcg gaaaagtgcc
     5221 ggtagatcta ggttggaaga agttatttgg aaaagagagc gacggaaaag agaaggaaga
     5281 agagccgcta cttcctaaag tggcaaaagg agaaatggtg acggtagatc tacaagttct
     5341 tgaaaaagaa acaaagccac caaaaccata taccgaaggt acgttgatca cggcgatgaa
     5401 aacagctggg aaaaccgtgg atagtgaaaa agcgcaatcc atattgaaag aagtggaagg
     5461 aatcggtaca gaagcgacac gggcgaatat tattgaaacc ttgaaacaaa aggaatatat
     5521 caaggtagag aaaaataagc tcgtggtgac gaataaaggg attttgcttt gccaagccgt
     5581 ggaaaaagag ccgctgctta cgagcgccga aatgaccgcc aaatgggaaa gctacttgtt
     5641 aaagattgga gaacgaaaag gaacacaaac cacttttcta gccaatatcc aaaaatttgt
     5701 ctctcactta ttggaagtcg tcccaggaca aatccaatcc actgattttg gatcgacgtt
     5761 acaagaagtg aaagcagcca gtgaaaagca agaagccgcg cgtcatttag gaatttgtcc
     5821 aaaatgccag gaacaagaag tcttactcta tcaaaaggtg gcagcttgta cgtctgaagc
     5881 ctgtgatttt aaattatgga caacgattgc caaaaagaaa ctcacagcga cacagctgaa
     5941 ggagattatt caaaatagcc gaacaagcca accagtgaaa gggttaaaag gtcagaaggg
     6001 ttcgtttgaa gcaacgattg ttttaaaaga agacttcact acaggctttg aattttctga
     6061 aaagaaaaaa acgaacttca agaaaagaac acgacgcact acaaaataat ggagggttaa
     6121 tcttatgcgt aatacaacac acaaacaaca agaaatcgaa aatcaaaaag ccaaaattcg
     6181 ttcagaacag gaaaaaatgc gtgccagcaa acgaagactg cagcaattaa agaaccagca
     6241 acggattcaa aaagaaattg aattagatcg ataaatatct ttcttgttaa tataaaacta
     6301 acgtgatata gttatgttag ttttatatta actttagggg aaaagcaatg aaagacaaaa
     6361 tccagtgcat ttttgataaa cataatggga atctatcctt gaaggatgct agaagtgaag
     6421 gcttatcgcc tatgacgtta gatcgattag ccgaaaagga caaaatagaa aaggtagcac
     6481 caggtttcta taccttaaaa gaagcgttcg tggatgaatt gtatctcgct caaagtatct
     6541 attccagagg tattttttct catgagactg cgctcgatct ttttcaagtc ggaacgtata
     6601 tccctaaaaa gatcaatatg atgtttccta aaggatacaa tgtttcaaag gagaaattag
     6661 acgagtatgc tattcaaccg cattacacga ataaagaaaa ttttgacctg ggaatcacag
     6721 aaacagaaag cttttacggc aataaaattt tagtctatga tttagagcga acgttatgtg
     6781 atatgtggaa tccaagatac aaagcaagcg tagaggtaaa acaagaagca ttaaaagaat
     6841 atatgacaag taccagtaga aatacaaata agctaagaag atacatggat attttaaaat
     6901 caccaaaaga aatgactttg tatatgttgc cactttattg agaggagtaa aggtgaatga
     6961 caccgacaca atttaaagca aaaacgagaa atttcgcaac agagaaacat ttaaatccac
     7021 aaattgtcca aagatattat atgatggaaa aattattaga acgtattgtt gaatcgcctt
     7081 atcatgatga ttttgtatta aaagggggat ttctgatcgg atcaaaatac gggttagaaa
     7141 accgttcaac tgttgatatt gatacgactt atcgaaattc gaaactaaca aaagaaaagt
     7201 tagaaactgt tttttctgag ttaacagctg atcccacaaa agatggaatt cgatttgaat
     7261 taaagggatt aacagagacg agggaagccg attattaccc aggttttcaa gcaaagttta
     7321 ttgcttatct tgagaatgca cgtgtaccat ttaaattaga tattacttca ggtgattcta
     7381 ttattccagc ggcattgatg tatgaacaca aattaatgtt tgaagataaa acgattcata
     7441 ttccagctta tcctacggaa caaattctag ctgaaaaatt acatgctacg tttagtttcg
     7501 gaaaagataa ttcgcgcatg aaagactttt atgacctgta tatgattcca aaactagaac
     7561 gtatcgatga gaaaaacttg tataagagtg ttcaaggaac gttcaaggaa agaaataatc
     7621 aatctgtgtt taaaaaattg tataatcagg aaatgcctca attgatgaag gatgaggggt
     7681 tgagggaaaa gtggaaaaga taccaacaag aaaattattt tgccaaagac atttctttcg
     7741 aatctacact aacttccgtc gattctttga tgcaatcaat tgtagagcaa gagaaagtag
     7801 aacgaaaaca aaattttaag agatcacaac aaatgaatca agaaatggag agataaaaat
     7861 gattaataat gtaactttag taggacgatt aaccaaagat ccagatttac gttatactgc
     7921 aagtggtact gcagtagcga cttttaccct agccgttaac cgaaatttca cgaatcaaaa
     7981 cggcaatcga gaagctgatt ttatcaattg cgtgatttgg cgcaaaccag cagaaacgat
     8041 ggcgacatta gctaaaaaag gcagcttgat cggtgttgtc ggacggattc aaacacggac
     8101 ttatgacaac cagcaaggac aacgtgtgta tgtgactgaa gttgtagcag ataactttca
     8161 actattagaa agtaaagcag cgacagagag ccgtgcgcat gcagatcaat cgtccaccag
     8221 tccaagcacc gccacctttg aacaacggga tacagcgacg cctaacaaca atggattgaa
     8281 cgcttcacag aatccatttg gtggacaatc aatcgatatt agcgatgatg atctaccgtt
     8341 ttagttcgag aaagaaggag taagcatggc aaaaaaaaat agtctgacga tggatctatt
     8401 gatacccgta attgcattta tagacgggat ttctttgggt atcactgaaa atcttttggt
     8461 aaatagaatt gcgaaaggat cactatttct tgtattcgtg tatcttgtct gttcttatct
     8521 tctaaaaaga gtaggaaagg ataattcctt ttggcgattg actaaagtca caataggcgc
     8581 gacagctgtt atacttacgg ctattctacc gctttatatg tagggttaac gggaaatcat
     8641 tgaacttctt gcgaaatatt gttataatga acatgaaaaa gaggagttgc gcaaacaacc
     8701 cctcattaac agcaccgttt aaagaacggc ggctcagatt aattatttat tgagaaataa
     8761 ccgatcctcg ctaaagtgac ggttatttct ttttgtcatt tttaagcata tttacaatca
     8821 aactaatcaa agcaatggta aacataccaa aaccaagaat ggtttgaatt gtctcatatg
     8881 cggacaaaag gcttactcct ttcatagatt ttagcactta cattcataag caccaccacc
     8941 ttccagaagt cgccaccgtc attaaacttt actgtcttga tcattatagc atatctaaaa
     9001 tcgaataaaa attctcaatt ttagctgttt ttgctataat tttagcgagg tgatcgcgat
     9061 ggaacattat actggtttac tcgataaaat tcgggtgatc aagacacagc cattgcttgt
     9121 gcgatttaca ttacacacga gtcatgaacc aatcaattgt gtagtggcca atatagaaat
     9181 agcggataaa ttgctgattt tggaagaagg caagtatact atttcagtga caggtcactt
     9241 caataaacgg aatcaattag tcattgaatc gatgcaaatt agaaaccccg atcattttac
     9301 gcgatcgatg ggcatataaa agaagagctg caatcctaat gtaggactgc agctcttttt
     9361 gttttacata gaaacgggaa caggaaaagg cctttttagg aaggcacaag tgccttctca
     9421 attgaaaaac ctttctctca ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac
     9481 gctgcacgtt cactaagata aggggtcttg caaagcaaga caaaatagaa aaaacttcct
     9541 ctcaccaaaa ggttcgttcc tgttcgttat ctctttattg atttgccaga ccggcaacaa
     9601 gttgcctttt atcaccaaaa agcgacaagg acaagggtaa atggcacgct gcgcgccctt
     9661 gtccttgtcg cttttcgttg attcattctg gccaacaaat caataaagaa agaactaacg
     9721 aaaggaagta aaacctttcc taagaggagg cagaatcaaa catgcgaaag aaatttgatt
     9781 attggggtgt tcccttcagc gaattattcc caaactatca tgcaccacat actgtcgaat
     9841 gcgattgtgg agaaagagcg aaatgtatca aaagctatcg tttgtatcaa tgtccaatat
     9901 gcgggaaaaa atataccttg tcttacggcg attacatttt gattgaagag aaaggaagat
     9961 aaaatgatgg ctcaaaatta ctatgacgaa tttgtcaaat tacctttgga taaaatggca
    10021 caaaaaatgg aggatatgac gttcctatac aacgaaacac gtgttccaaa aaaacattat
    10081 aaagaaaaat tgtcggtagc tgtggaagaa atgattgaat caggtgtcga aatgaatctt
    10141 attgcgacgt actatcgaac actggaagaa ctgaaaaagc aaaatgcaaa atggtttttc
    10201 caagccttac tatgcttgga agtaggtgtc aaaccaagca ctattaaacc ttctgaatac
    10261 caagctttag aactaacgta tgcgaaattt atcgaaacga aaaaagccaa gactgtttca
    10321 agtgaatggt tagattattt tgaaaatatc aataagtatg gcgcctatta caccatgaaa
    10381 aaggaggaca acgaaaatga ataatgtagt ttatcaacta acaatggaag acatttctcg
    10441 ttttttaaca aacaaagaac atttgaatga agtaatcaga cggattcaaa aagactttag
    10501 ttgtatggaa gaaatgaagt actttgttca aaacgttgaa gaacagttat atttggaaag
    10561 cgaaacgagt caaacaaagg tcacagtcag caataatcgt ttagatgtgt ataaacgtcg
    10621 tcctgaatca ttaaaaaaag gagcggagct tctacgacta gaaacagaaa aatacgtcat
    10681 gaatgtttac ctagaaaaaa gtgagttggt cgaaaatttt attagctaca cgatttgcag
    10741 gaaacactat tactcagaat cagaatatta ttcaattttt gagagcatgg aattaatgga
    10801 agaagaaatg gaagagttaa acagtaaaga tgcgacggta gacgattatt accttgtatt
    10861 tactagattt ttaacgtgtg gaacggaatc tatcgtgcta atgggaatag attacgaact
    10921 cgctgtaccc gaagcgtttt tgagggaata tgtagaagaa gtagataacc caggggatga
    10981 ttggtacacg actttaactg attttttaga cacctacact tacgacgata cagaagaaat
    11041 ccaaaatgag cttgaccgta aacaaatgcc atatcaacga tttgaaagga aaaaaggtca
    11101 ataatcattt ataccgaaaa gtgagaatgt gtgaaataag aacaaaaaac cttgaaatta
    11161 agggaatggt tcttatttcg caccaatcgc tccaaccgcc cccgccgctt aggtggtgcg
    11221 aaataagcga gcaaagcccg ctaaccaaag agaaagaagg agatttatat gaaaaagatt
    11281 attcccttat tattagtact atttgttggc gaaatgctta tgcgtcatgc tgcaactgtg
    11341 catttaaact tcgtagtatt tttggtaata ctggtgtttt gtttgacctt ttggcggttt
    11401 gtattagccc tcgtgagttt actattcaag atgattgcag ccatattttt cataggatta
    11461 tttcgatgag aggagagagt atcaatgcca attgcaatag gaaataaacg gttacccgtt
    11521 acgttggatg aaaagagaca aaaagaatta cagcaactta aacagaaata cggtaaaagt
    11581 gaatccagga ttatgtgcat tgcgttagat ttattgattg cgcaggaaaa agcaggattc
    11641 aacataccag cgctcaaaaa gtgacgtcac tttttgactt aaaaaataaa agtgatagca
    11701 cttttatata gtaaaaagaa gaataaacgt taagggatag aaaaagagaa aagaacaaaa
    11761 aaagagctaa cagtaccatt gttagctctt atgcagtaat gaaaaccaag cctttaaaaa
    11821 aggagatgtt tcatcacaaa cacaaacaga aaaataaaaa aatcaaaaat ctaataatca
    11881 taaattgcta ccgaagcacc ttttattata attaatcaaa tata
//
LOCUS       DASHWW010000079        11540 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.079, whole genome shotgun sequence.
ACCESSION   DASHWW010000079 DASHWW010000000
VERSION     DASHWW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.079"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(55..564)
                     /locus_tag="U2R64_002425"
     CDS             complement(55..564)
                     /locus_tag="U2R64_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919211.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDVSPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(554..1279)
                     /locus_tag="U2R64_002426"
     CDS             complement(554..1279)
                     /locus_tag="U2R64_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919212.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(1502..3622)
                     /locus_tag="U2R64_002427"
     CDS             complement(1502..3622)
                     /locus_tag="U2R64_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEM8919213.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            3889..5031
                     /locus_tag="U2R64_002428"
     CDS             3889..5031
                     /locus_tag="U2R64_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEM8919214.1"
                     /translation="MKKGYPLIQKEDLAHPQKETTQWVELVDSQNQFIAKGYLGKQNK
                     GIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNGEGDGIGGLIVDY
                     YAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNLPESQFIYGKEAP
                     EPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVLNMFSYTGAFSVA
                     AAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEYFKYAKRKQFLYD
                     MIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNAANVSIEQFQTMI
                     EEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH"
     gene            5047..5805
                     /gene="aroD"
                     /locus_tag="U2R64_002429"
     CDS             5047..5805
                     /gene="aroD"
                     /locus_tag="U2R64_002429"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEM8919215.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            5828..6313
                     /gene="ybaK"
                     /locus_tag="U2R64_002430"
     CDS             5828..6313
                     /gene="ybaK"
                     /locus_tag="U2R64_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HEM8919216.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(6384..7637)
                     /locus_tag="U2R64_002431"
     CDS             complement(6384..7637)
                     /locus_tag="U2R64_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8919217.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            7754..9103
                     /gene="gdhA"
                     /locus_tag="U2R64_002432"
     CDS             7754..9103
                     /gene="gdhA"
                     /locus_tag="U2R64_002432"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEM8919218.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            9215..10561
                     /locus_tag="U2R64_002433"
     CDS             9215..10561
                     /locus_tag="U2R64_002433"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEM8919219.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(10869..11255)
                     /locus_tag="U2R64_002434"
     CDS             complement(10869..11255)
                     /locus_tag="U2R64_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8919220.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(11304..>11540)
                     /locus_tag="U2R64_002435"
     CDS             complement(11304..>11540)
                     /locus_tag="U2R64_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEM8919221.1"
                     /translation="PRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVK
                     GLESRFESILLAYSVLLSRAQRRFGGTLRYSLGY"
BASE COUNT         3745 a         2071 c         2334 g         3390 t
ORIGIN      
        1 aaagatcatg aatcgatctt ctataccgct tgtttttact ataaaatgat tgatttagcc
       61 cgcgggctct aaacgatcaa tataaggact ttgagcaata gtagcatcat gagtaaagag
      121 taagatacct tgattttctt catgagctaa ataagaaagc aagtggagta gctcttggat
      181 ctccaataca ctaagttcat caaatgtatc ttcaataaca atattgtttc gcttggaaag
      241 caaggcatga agtaattgca gctttacttt ttcaaaagac gtcaactcag ctgccgcaca
      301 attaagcaag gaaggagaga catcaagttt ttcttgatag gccaaacgat cttgtttgat
      361 ttctttttcc ggtacatcca acaggacatg gtctttaaga ttcagataag gaaacatcgg
      421 ccaatttttt tggatgatcg caaaattatc cagttttgca acaagaacct cttttttcaa
      481 gtgctccaat attttatgct gtttttcgag aggacacaaa ataacggtca agtgttcagc
      541 atgaatcaaa tattcaggtt tcattacgtc caggcctcct actttgcaaa tgatggataa
      601 aaaaagtgaa agggaataga ctaagaatga gacagcatcc actgagccca ataagagttt
      661 gggcaaatcc cttaagtata tctgtgaaaa aaagatcatt ttggaaatcg atggtaaaaa
      721 aagtctgttg atccatcgga attgtaagtc cgcttaccga agtcaagata tcacggatat
      781 ctggcagttc agtagtcttt aagacaagaa aattgatcct ttgaagaagc gcttcataaa
      841 ctgactggaa gcttacgatc cacaataaaa ccaagataca acaaagaaag agaggaaaga
      901 acagctgcca gaaaataaaa aggaataatt tggttttaga aagaccagtc aggtgccaat
      961 tgatcaattc ctgcttgttt tgcctgactg aatagtaaaa gaaaaagata aaaaggaagg
     1021 caaatagaaa aaataaactg aatatgcctt ttatataaaa tcggctagct aattctaaag
     1081 ccggaagaag ctctgtagat gcagaagcgc caataaatga aagccgatct tggacttgat
     1141 tggctaaagc cgattgcaaa tggtaaagag tcaggcatgc tatcaataaa aaagcagaaa
     1201 agcttgaaaa taaacaatag agtattgtct gctttttgta ataaattaat cgagcagtag
     1261 catagcggat tattttcata cttttcacct ctataaaaag tatagaaaat gaatatgaat
     1321 aaagtatgaa attcctttag tgaaatcacg aattaaaacc agaaaatatt ttgtaaaaag
     1381 caagaggttg tgaagaagct gccctattct attaccgtag atgcaagctt ttgaacactg
     1441 tttattcgaa aagaggagca gcgacaataa ttttgtcgct gctcctttta aatttatttt
     1501 atcattcgga agaacttgtg gtcgttccgt gaagttcttg gtacgtttgc gttttataaa
     1561 gatcaacagt tgattgtccg ttgtgttcac taaagacact agttgacttg tcaccaagag
     1621 atttttcagc ttcttttaat ttctctaagc cattcttgta gtcataatca ctggtatcaa
     1681 ttgggtctaa tccactattc gtatagaacc gaagaagatc accattattg atttggtcag
     1741 aaacagctaa ctgtttatca actttttctt tcagtgaatc aatttcattc tgtacttcct
     1801 cagtaggttc agtaatagct tcaccagttt cgttactata gatcgtacca ccgtagtaag
     1861 tatattttgg tgtaacaaaa tcaccatcac ggaaagaaac aagctgttca tgatctttcg
     1921 agaatagatc ttgtcctaac tgaatataat tttttgtatc tacacctagt aagtgaagta
     1981 atgtaggcaa ggcatcaact tgtccgccgt aagtgtgatt gattccgccc tgtgtttgtc
     2041 cagggatatg gatcatataa gggacacgct gcatttgtgc attgtcgtag tttgtccaag
     2101 tagaacttgt ttttccaact aattcagcta gatttttatt tcttgaattc gagacaccgt
     2161 aatggtcacc gtaaaggacg atgactgaat tatcatacaa gccgctttct ttcaaataat
     2221 tgaagaattc ttgtacggcg gtatctaaat aattggctgt cgcaaagtaa ccgttgatcg
     2281 tttcatcatt tgtattggct aacgggaatc ctgcttcgtc attggtgaat tttgaataag
     2341 gataatggtt agatacagca atgaattttg aataaaatgg ttgttgcaga cgttccaagt
     2401 attgtacgga ttgttggaaa aatggtttat catgcaaccc gtattggaac gaattgtcat
     2461 cattaacatc ataataagaa gaatcaaaga aataatcata tcctaaattc ttgtatgtct
     2521 cgtttcgatt ccagaatgta ccagcgttcc catggaatac cgcactaatg taaccttgtg
     2581 tttgacttaa aatatcaggt gcagcttgga aagtattttt tccgcctaat tgtgtgaaca
     2641 aggagccttg attcaagcca aacaatgaat tttccatcag cgtttccgca tcgcttgttt
     2701 ttcctgcttt tacttgatgg aaaaagttgt caaaactgaa cgtgctgttg ctgtggtaaa
     2761 gactattgat gaaaggtgta acttcatgct ggagaccatt ctcatctgtc aatttataat
     2821 cgatcaggaa ttgctggaag ctttctaaat ggatataaat cacatttttt cctctagcga
     2881 gcccgaacaa atcgtcattt ggtgctgcat aatgttcttt tacataattt tctacttctt
     2941 tcatatcatt gggacttgct tctgcccgca cttggtttgt ctggtaagtt tgaacaccgt
     3001 cataaaccat gaaagcattc aagccaagat atttgaccaa ataatcacga gagaatgttc
     3061 gagtcagcaa ttctggacga tcagcttccg ccataaaaag atttcctgag aaaatcataa
     3121 ctgctaatgt agagatcgca aaagccattc ttgctcggat cgggcgaggg tccaacttga
     3181 ttttttttgc aatcagcaga acagtcaaga taataaaatc gatccaatag atcacatcat
     3241 atgggcgaaa cagtcgaatg gcactttctc ccagaccact cgctactttc ccagcaccta
     3301 aaatcgtgtt gatcgtaatg aagtccgtga attctcgata ataagtgaca ttcgaaaaaa
     3361 caagcaatgt caaaagaaaa taaatgacca tcatcgtgat ataagcaact ctagggcgtc
     3421 tgatataaag agcaattcca agtaataaca atgtagttgc aatagggttg ataaacaaga
     3481 taaagtattg aatgccactt tcgattccga gatggaaatc aactaaatag gcaaaaatcg
     3541 ttttcaacca aagtaaaacg actagtaaag aaaaaaatcc gagcctctta ttcaaaaagg
     3601 caggtgtttt tatacatttc aagataatct tcctttctgc acttcttaat cacagaagtg
     3661 tcctgaaacc atgttacaca gctcacttat tctcatttat tttactagta tgacaatata
     3721 gtgtcaattg aaaccagaag tttatgctgt ttcattaagg ttttctttaa gcttcatgaa
     3781 aaaatgagca gtaagacaag tcctatgttt tttgttatac ttgggaagag aaagctaaag
     3841 caggtgaagg aatgaaagta aaagtaaaaa aaaagagcaa gcaatcgatt gaaaaaagga
     3901 tatccactga tccaaaaaga agaccttgct catccccaaa aagaaaccac gcaatgggtg
     3961 gaattagttg attcgcaaaa ccaatttatc gcaaaaggat atctaggaaa gcagaataag
     4021 ggaatcggtt gggtattgag ccagcagaac atcccatttg atcaatcttt ttttgaagaa
     4081 ttttttgtga agtcaaaaga aaaaagaact ttcttttttt cagatgattc tactaccgct
     4141 tttcgtatat tcaatggaga aggagacggg atcggcggtc tgattgttga ttattatgca
     4201 ggttatgctg ttttttcttg gtataacgaa acgttatatg cacatcgtga attattgatt
     4261 caagcttttc gtgaaatcta cccggaaatc ataggaggct atgagaaaat tcgatttgaa
     4321 tcagtaaatc tgcctgagag ccagttcatt tacggaaaag aggcaccgga acccttgatc
     4381 gtaaaagaaa acggagtaaa atttgccgtt tatttaaatg aaggattaat gactgggatc
     4441 tttttagacc aaaaagaagt acggggatca ttagcagaag gtttcgcttc tgggaaaaca
     4501 gttttgaaca tgtttagtta taccggcgcc ttttctgttg ctgccgcaat gggaggggca
     4561 atcgaaacaa caagtgtcga tctagcaaaa cgcagtttaa aaaaaacaca ggaacagttt
     4621 gaagtgaatg gtttggatgt cgatcagcaa aaaatcattg ttatggacgt attcgagtat
     4681 ttcaaatacg ccaaaagaaa acaattttta tatgacatga ttgtattgga tccaccaagt
     4741 tttgccagaa ataagaaaaa agtctttcgc gtagcaaaag attatgggga actggtcaag
     4801 gatagtctgg atattttagc agaagacggg atacttattg cgtctacaaa tgctgcgaat
     4861 gtctcgatag aacaattcca aacaatgatt gaagaggaat tccatgccaa aaatgtttct
     4921 tttgaacaac ttgctttata tcgtctgcca aaagatttcc agacgacgga taccttttta
     4981 gaaggcaatt atctgaaagt gtttgtttat caaattaaaa ataaccatta gaaggagcga
     5041 tgcagaatgg ttcgggtaaa gggattgaat ataggaagcg gtagaccaaa gatttgtgcg
     5101 cctcttatcg gggccgtccg agaggaagta ttacgtgaag cagttcttgc acgtgaagca
     5161 ggggccgatt tagtcgaatg gcgagtcgat cattatcgtg aagttttttc ttttgatgaa
     5221 gtagcagaaa cattggttct tatccatgag atgcttgatg gactgccgtt attatttacg
     5281 tttcgtacct tagctgaagg cggagaacaa gacatatcga tccgtcagta tcgcgacctt
     5341 tatgaacatg tgatacacac aggattagta gatatggtcg atatcgagtt gttcaaagta
     5401 gaaagtctag gaaaaagact gatagaggaa atcaagtctt taaacattcc tttaattatc
     5461 agtagtcatg attttaaaga aacaccagca gaccctgtct tgctttaccg attgaatgtt
     5521 atggaacatt ttggagccga tatcggaaaa ctggcagtaa ctcccaataa tgaacgagat
     5581 gttttgcggt tgatggagtt gactagacgg gcaaatgctt ttgtctccat gcctattatt
     5641 acgatgtcca tgggaaatct tggtaaaatt tctcgtctgg ttggcggaac gacgggttcc
     5701 gttatgacat ttggttcctt aagcagcgat tctacttctg ctccaggaca attaccggtc
     5761 aaagcattga agcaaattat tcaattatta aatgaaccgt tgtagaacaa gtttgaggtg
     5821 atattttttg gcaaagaaaa aaatagtaaa aacgaatgca atccgtatgg tcgaacaaaa
     5881 aaagattccc tatacagagc acgaatatga gtgggacgaa agccacctaa gtgcgtcatc
     5941 ggtcgctgaa cagcttccag aaagccaatc tcgtatattt aaaacactgg ttgctgtggg
     6001 caatgtgacg gggcctcttg ttgctgtgat accgggagaa gccgaattga atctaaaaaa
     6061 attagcaaaa gtttcaggga ataaaaaagt agaaatgctc catttaaaag atttggaagc
     6121 aacgaccgga tacatacgtg gtggctgctc gcctataggt atgaaaaaac tatttcctac
     6181 ttatttagat caaattgcag aaagctatga acaaatcatt gtctcggctg gcagaagagg
     6241 gctacagatg gagttagcac ctcaagatat ctgtgcatta acgagcggac aatttgcaga
     6301 tataaaacaa taaatcatac gtataaaaga aagaaggagg ccgggatgtt gtttgtccag
     6361 tctccttctt tcttttttat acattatgct ctttgcccgg cattcattcc tgctacatgc
     6421 cctgtagcga aagccgctgt gatattaaag ccgccagtat aaccattgac atccagtaat
     6481 tctcccgcaa aatacagacc atcaatgatt ttactctcca atgttttagg ataaatttcc
     6541 tttagagaaa cccctccgcc agttacaaat gatttctcaa taggaaaagt tttgttgatt
     6601 gatagcttaa actctttgca tagttgaaca aaatcttgaa tttgtttttg agaggcttgt
     6661 tgtcctgtca gatgatccat ttcaagccgc tcaagaaaga aaactaacaa tcgctcaggc
     6721 aatataccat gccaagcatt gaccaagttc tttttggttg ctttactttt ttctgtcaat
     6781 atatgaataa gctcttgttt ggtttgtgta gggaaacaat ccagagaaag tgtcactggt
     6841 tctcccgttt tctctaattc tttattgaca aaacttgaac aacgcagtgc agccggacca
     6901 gaaataccga aatgggtgaa aagtaaatcc atcgtatgtt cagtcaatac acgacctttt
     6961 ttatttaaaa cgcgtaaagt gatgtcttgt aaagaaagcc cttgaagtgt tttctcctga
     7021 atatacggtt catccgatat caagggggac tctgtcgcat aaagaggcgt caccgtgtga
     7081 cccactcgct tcacgatctt gtacccatct ccagtagaac cagtagatgg ataagtccgt
     7141 ccaccagttg ttaagataat ggcaggagca tggaactctt cgaattccgt gcgtataccg
     7201 taaattttat gttctttgtg gatcaatttc tctactcgag tagagaatag aagcgtcaca
     7261 tctagttctt tcagacgatt gagcaatgct tcgataatcg tttttgattt atttgttaca
     7321 ggaaacatcc gtccatgatc ctcttctttt aaatgtacgc cttgtgattc aaagaagttc
     7381 atgatatcga aattattcca ttgcgcaaac gtactatata aaaactttcc atttccagga
     7441 atatgtgcaa tcaaatcatc aacaggacga ttgttcgtaa cattgcaccg accaccacct
     7501 gtcatcagta gtttttttcc tgcttttttg tttttttcga tcaagagtac gcgtgcgcct
     7561 tgttcagctg cactgatcgc tgccatcatc ccgcttgttc cagcgccgac tacgatcaca
     7621 tcatacagtt tttccattcc ctcacctcaa ggaaagtgta gcatatctga agaaagaaaa
     7681 cagaaaaaaa tgttttgagc caaaagagaa aatgagctaa aatgagggaa gataagcaaa
     7741 ggagcgtgga acgatgacaa acgcaacaga atatgttcaa gcaattcaag aaaagctaca
     7801 tcaaaaggat caagggcaag aagaattttt acaagcaatc gatgaattca tgcccacggt
     7861 tatgtctttt ttggacactc atcccgaata tatcgaaaag aatatcttag aacttttaac
     7921 ggaaccagaa agagttattc aatttcgagt gccttggcaa gatgatgaag gaaactggcg
     7981 agtaaataga gggtaccgta tccaatacaa ctcagctatc ggcccttata aaggtggatt
     8041 gcgcttccat cctagtgtca atctaagtat cttgaaattt ttggcttttg aacagatttt
     8101 caagaatagt ttaaccggtc tgccaatcgg tggaggaaaa ggcggaagtg acttcgatcc
     8161 taaaggaaaa tctgataatg agatcatgcg tttttgtcaa agtttcatgc tggaattgtc
     8221 aaaacatatc ggcccatcga ttgatgttcc tgcgggagat atcggtgtag gagctagaga
     8281 aatcggctat ttgttcggcg aatataaacg attgaaaaaa tatgatactg gtgtgttgac
     8341 aggtaaacct ttggattttt ggggaagtaa gatacgtacg gaagctactg gttatggatt
     8401 agtgtattat gtcaaacatc tattgaacga agaaaaagat tcatttaatc aaaaaacagt
     8461 ttttgtttcc ggaagcggga atgtagccat ttatgcaatc gaaaaagtgc aagagctagg
     8521 cgggaaagtt gttacatgtt cagattctag cgggtacatc tatgatccag aaggaataga
     8581 tgtgaaacta ttgaaagaag tcaaagaaat caatagacaa cgtttgacgg aatacgcaaa
     8641 ccaacgtcct tctgctattt atcatgctgg agaatctgtt tggacattga aagaaaaagc
     8701 ggatatcgct ttgccatgtg ctactcaaaa tgaaatagac gaaagcttgg ccgaaatctt
     8761 agtagaaaat gggatcaaaa tcgtagcaga aggcgctaat atgccatgta cagtaaaagc
     8821 tgtttctgtt cttcatgaag caggcgtgtg gtattgtcca ggaaaagctg ctaatgctgg
     8881 aggagtagca gtatctgctt tagaaatgag tcagaacgtc cagcgattga cttgggaaag
     8941 agagcaagtg gatgagcagc tggatcaaat catggaaacg atttaccata cgtgtcgcca
     9001 aacagcagcc gagtacggcg acgaaaaaaa tctgcttctt ggagcaaatg ttgctggatt
     9061 tgaaaaagtt gccaaagcaa tggcagcaga aggtttagtt tgaaaaatga aactttcttg
     9121 gaaatattgt cagcattttg tttatttgct tgaaaaataa taaaaaaaaa cgtaaagtat
     9181 tacctgtaga gtaaacctat aaggaggaga acaaatggca cacattcatt ttgactattc
     9241 aaaagtagca ccgtttgtca acgaacaaga gttagggtac atgcaaagcc aagtaacagc
     9301 agcccacaac gaattacggg aaggtactgg cgcaggaagc gacttccgcg gctggatcga
     9361 tttaccaacg aactatgaca aagaagaatt tgcacgtatc aaagaagcag ctaaaaaaat
     9421 ccaatctgat tctgaagtat tagttgttat cggtatcggt ggttcttatt taggcgctcg
     9481 tgcagcgatc gacttcttga atcacacatt cttcaattta ttagatagca acacaagaaa
     9541 agcaccacaa atcttctttg ccggaaattc aatcagctca acatatattg ctgacttgat
     9601 cgaagtaatc ggtgatcgcg acttttcagt aaacgttatt tcaaaatctg gaacaactac
     9661 tgaaccagcg attgcgttcc gtgtattcaa agagcttctt gttaagaaat atggacaaga
     9721 agaagcaaac aaacgtatct acgctacaac agataaagca aaaggtgcag ttaaagtaga
     9781 agcagatgca gaaggttggg aaactttcgt gattcctgat gacatcggcg gacgtttctc
     9841 tgtattaact gctgttggtt tgttaccaat cgctgttagt ggtgcagata tcgatgcatt
     9901 gatgcaaggt gccgctgatg caagcaaagc atactcaagc gacaaactag aagaaaacga
     9961 agcttaccaa tacgcagcaa tgcgcaacat tctttaccgt aaaggcaaag taactgagtt
    10021 gttgatcaac tatgaaccag gaatgcaata cttctcagaa tggtggaaac aattgtatgg
    10081 tgaatctgaa ggaaaagacc aaaaaggcat ctatccttca agcgcaaact tctcaactga
    10141 tttgcactct ttaggacaat tcatccaaga aggacgtcgc aatatttttg aaacagttgt
    10201 gaaggttgaa aaacctcgta aatcaatcac aattcctgaa caagcagaag atttagacgg
    10261 tctaggctac ttgcaaggaa aagaagtgga cttcgtaaat acaaaagcat ttgaaggaac
    10321 attgcttgct catacagacg gtgacgtgcc taacttgcta gtcaaaattc cagaaatgga
    10381 tgcttataca ttgggttata caatgtactt ctttgaaatt gctgtaggta tttcaggtta
    10441 cttgaatgga atcaacccat tcgaccaacc aggtgtagaa gcttacaaga aaaacatgtt
    10501 cgcacttcta ggcaaaccag gctttgaaga tcttgctaaa gaattgaacg aacgcctgta
    10561 agataagggt ttttcgctag atttaaataa tcagtgatag aaacatgttc gctttaaaat
    10621 gaaaactggt acccatttag gtactcaaac atactgcatc gtttattcag aataaggggc
    10681 tgtgacaaga cgtttgtcac agtcccttgt ttgtatagaa atcgattgat tgccttgctc
    10741 tttagtttgt tttaggactt taagaacagt gaggctgact tcgaaggtta attctgtttt
    10801 tttgttttct agaatcagta agcaaaaaag cactcacttc gagtgctttt ttgcgatata
    10861 ttcttagctt aagataggcc taatttttct tttacagatg agggtacctt atcgctggta
    10921 attacttttt tctctatgat ccgcttttcg cttgctttca actgcaagat cgttccttcg
    10981 gggtaagcag aaccattggc agagtcacca gaagtaatga catcgaaatc taactgtctt
    11041 ttttcaccgt tttcagcata agcatctacg ttgtatttaa aacctcttcc aattacttcc
    11101 ccattatctg ctttgatatc agtttctgca ggcattggag ctttgactac cgcataataa
    11161 tctttaccta cataagtaga ctgatagtag tcccaacctt tccatcctat aaaagcaatc
    11221 aatatgataa cgatcaaccc taaaattttt ttcatgaaag atctcctttt ttatttttat
    11281 tatacccgtg gtgctagtta attttaatat cctaaagaat atctcaaagt tcctccaaaa
    11341 cgtcgttgtg ctcgacttaa tagaacactg taagccagta atatgctttc aaatctactc
    11401 tctagccctt taacagaacg tgagttgaaa ttttgacaac ctaatttttc taaggaagaa
    11461 aaaacagtct caactgtttt tctttgtttt ccaagtaagc tgtggtctag tttttctgat
    11521 ttatccatgt ttttacgtgg
//
LOCUS       DASHWW010000080        11440 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.080, whole genome shotgun sequence.
ACCESSION   DASHWW010000080 DASHWW010000000
VERSION     DASHWW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.080"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            184..1182
                     /locus_tag="U2R64_002436"
     CDS             184..1182
                     /locus_tag="U2R64_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8919222.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="U2R64_002437"
     CDS             1294..1803
                     /locus_tag="U2R64_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEM8919223.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="U2R64_002438"
     CDS             complement(1833..2492)
                     /locus_tag="U2R64_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEM8919224.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="U2R64_002439"
     CDS             complement(2494..3258)
                     /locus_tag="U2R64_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEM8919225.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="U2R64_002440"
     CDS             complement(3266..3943)
                     /locus_tag="U2R64_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEM8919226.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="U2R64_002441"
     CDS             complement(3980..5365)
                     /locus_tag="U2R64_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEM8919227.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="U2R64_002442"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="U2R64_002442"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="U2R64_002443"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="U2R64_002443"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HEM8919228.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="U2R64_002444"
     CDS             6304..7161
                     /locus_tag="U2R64_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919229.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="U2R64_002445"
     CDS             complement(7242..7577)
                     /locus_tag="U2R64_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919230.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="U2R64_002446"
     CDS             complement(7644..9014)
                     /locus_tag="U2R64_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HEM8919231.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="U2R64_002447"
     CDS             complement(9092..9628)
                     /locus_tag="U2R64_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8919232.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="U2R64_002448"
     CDS             9937..11418
                     /locus_tag="U2R64_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919233.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3515 a         2301 c         1854 g         3770 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgctat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcgctatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct
//
LOCUS       DASHWW010000081        10660 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.081, whole genome shotgun sequence.
ACCESSION   DASHWW010000081 DASHWW010000000
VERSION     DASHWW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.081"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            333..2279
                     /locus_tag="U2R64_002449"
     CDS             333..2279
                     /locus_tag="U2R64_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8919234.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2282..2737
                     /locus_tag="U2R64_002450"
     CDS             2282..2737
                     /locus_tag="U2R64_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8919235.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2751..4079
                     /locus_tag="U2R64_002451"
     CDS             2751..4079
                     /locus_tag="U2R64_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEM8919236.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4113..4397
                     /locus_tag="U2R64_002452"
     CDS             4113..4397
                     /locus_tag="U2R64_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8919237.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4399..4914
                     /locus_tag="U2R64_002453"
     CDS             4399..4914
                     /locus_tag="U2R64_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HEM8919238.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4930..5592
                     /gene="rpe"
                     /locus_tag="U2R64_002454"
     CDS             4930..5592
                     /gene="rpe"
                     /locus_tag="U2R64_002454"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEM8919239.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5599..6171
                     /locus_tag="U2R64_002455"
     CDS             5599..6171
                     /locus_tag="U2R64_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8919240.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6358..7878)
                     /locus_tag="U2R64_002456"
     CDS             complement(6358..7878)
                     /locus_tag="U2R64_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEM8919241.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8121..8306)
                     /locus_tag="U2R64_002457"
     CDS             complement(8121..8306)
                     /locus_tag="U2R64_002457"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HEM8919242.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8290..8472)
                     /locus_tag="U2R64_002458"
     CDS             complement(8290..8472)
                     /locus_tag="U2R64_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919243.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8713..8931
                     /locus_tag="U2R64_002459"
                     /pseudo
     CDS             8713..8931
                     /locus_tag="U2R64_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9426..10025
                     /locus_tag="U2R64_002460"
     CDS             9426..10025
                     /locus_tag="U2R64_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8919244.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10089..>10660
                     /locus_tag="U2R64_002461"
     CDS             10089..>10660
                     /locus_tag="U2R64_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HEM8919245.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIG"
BASE COUNT         3525 a         1675 c         1989 g         3471 t
ORIGIN      
        1 taggactcaa ttgttcatag atgagcattt gtaattaagt tatattataa taaaaaaata
       61 cgaattttag tgacgccatt atattgtttt tatttttcaa ttgtaatatt tcatattact
      121 tccataataa ggagtatttt ctattggaat atcttagctc ttttaaggat ttctcctttt
      181 ttgtttctca ttttttaaga ttatttggat ttcctttaca acaaacttcc acaagtatta
      241 ttgacataga tgtaattgag ggaagggggt tccagtgcta gaataaataa tgaaaagagg
      301 taacaaatgc tagcgttaag aggtgaacaa gtttgattga aagacatgta aatttattaa
      361 aattattaag tcgacaagaa gactttaaac ccgcttcttt ttttagtgat aaattggcag
      421 tgtcgaccaa gaccatttat caagatattg aattgttgga agattatgta gttaattacc
      481 aagtaacaat tgagcgatta ccttctttgg gtatcaaact cataggtgat aggaaaaacg
      541 ttgaacattt gatttcatcg gtagaaaatt atcttgaaaa agatatttat tctccagaaa
      601 aaagacgtgt cgagatcatt aaagaagttt tgtttggtga taagcctgtt tctttaactc
      661 atttgtctca aagttttatg gttagtaaaa catcgttata caatgacctg agaattatca
      721 ataaaattat tggcagtgga gaagttaagt tgcagtcatc tgcagaagga attagtttta
      781 ctggtaatga acaagcaatt caacgagcaa tcaagcaact tgtattctat tatgcgaatg
      841 acatggaatc aaaaacattt tttcaagttt taaatatgtt gtttgattca aaagttatta
      901 gtgtcattca tgatttgcta ttcaatgatt acagtgaact gactgaaaag gtttctgatt
      961 actatgttcg gtcattgatt tctactttag ttatccaatg taaccgttta ctgaaaggtc
     1021 atcatttaac tgttgaagaa gaattcctct tcaatagcat tcgctatatg gaaacgtaca
     1081 ttgtggcaaa tggtttaatt gaagaattga aggcaaaatt gaatcttcca ttttatgacg
     1141 cagataaaga atatctatgt cgtcaactat ttgcacatcg tgtgacaaat aatttaaaaa
     1201 ccagcaatga agagtacgct atgagcgttc ataaattgat tgaaagaatg agtgagattg
     1261 aaaaaattga tttgactcaa aatgatcgat tatatcaatc cttattgtat catgtgccag
     1321 caatggtcct tcgtttaaaa aaaggtatta aaattcaaaa tccgttatta gaaaatatca
     1381 aatctcaata ttcagaactc tttagcatag tatggtacgc catgtccatc cttgaagaag
     1441 aatttgatgt gactttaacg gacgatgaag tttccttaat tttgattcat tttcagattg
     1501 ctattgaaga tcagtccaaa gcaaataata tcatcattat ttgccaatac ggtatttctt
     1561 ctgcgcaatt aatttacaat aaagttcgac ggtttttacc agcaaaagat aatgtagaaa
     1621 tatcaacttt agataagttt catttagctg aaattgggga agttgatttg attatttcct
     1681 ctctttcctt tgatgcaggt ggtataccct tagtaagggt atctccattg gtaagtaaaa
     1741 cagattatat gaatattatg gaagcttata ctaaatattt aatagaagaa ccttcgcgat
     1801 ttattcaaaa tgaactgatt cctaaagcgg ttaaagttcc caccatatct aaatttgttc
     1861 aatcatcttt agtaaaaaca ggagtacagg tggaaagcaa agaagaatgt ttggatttga
     1921 tgatttccga actagaagcc aattcattag ttactgaaga gtttcgtgct tctatcttct
     1981 ctagagagaa aatggggaat actaatttag aaagtggtgt tgctttaccg catgcgaatc
     2041 catcaatggt cattgaatcc aacattttta ttgtagcatt aaaaaatgcg attaattggg
     2101 gcgatcgaaa agtcaaatta gtcattatgg ttagtttagc tgaagaagat gtatctgaga
     2161 ttagaggagt atatgaagaa ctttaccaat ttattgggca aaaagaaatg gtcgatcgct
     2221 tgttacaagt tcatgatagc gaaaaattac taagaatttt tcaacaaaaa ggagaataaa
     2281 aatgtatcta gataaagaat tatgtttatt tcaattagaa gtgaaagatc aaaaagaatt
     2341 gtttcaagta atgtctgaac aattaaaaaa cgctggttgc gtgaaagata gtttcttaga
     2401 aggtatcacc aaccgtgaac aagaatttcc aactggatta gaagtaaatc aaattgggtt
     2461 tgctatccca catacagatt ccgcacatgt aaatagctct caaatctgtt ttgcctcatt
     2521 aaaggaacca ctggtatttt cagatatgac agataaatct catgaaatac ctgtacgttt
     2581 agtctttatg ttggcaatgt cacaacctca tgaacaaatt gatacactac aaaacttagt
     2641 tagcctattt caaaatgaag aaaaagtaaa tgaattactt gcatgtacca cgaaagaagc
     2701 atttattgag ttagtacatt ctgcaggagt ttattaggag gaatagagag atggatattg
     2761 tattaaatgc ctttgaatgg tttattggat tagggtcaaa cgtcttttta ccactgatta
     2821 tttttgtaat cgggatatta tttggattaa aacctggtaa agcatttgtt tccggcgtta
     2881 ctgttggtat cggttctatt ggtttaggat tagttttaag tttattatca gatggtttag
     2941 gaacagcaat tcaacaaatg ggggaacaat acggtggtgg cctgaatatc ctagatattg
     3001 gcgtaggtgt tggtggacct ttggcttact ctacatcatt gggaatttta atgattccaa
     3061 tttcattaat tcttaacttc atatttgtgg ttttgggttg gacaaaaaca ttgaatgttg
     3121 atatttggaa cttttggttc gcaattttcc taggtatgat tactcaatct gttacgggaa
     3181 acttttggtt tggcttaatt ggcgcgattg tcgcagtaat tttacaatgg ttcttagcag
     3241 atcgtacaca aaaaactgtt agcgaatttt tcggctatcc aggaatctct atcacacata
     3301 tgatgggatt atcaggagta ctatttgcca aaccagtaaa ttgggttttt gatcgtattc
     3361 ctggatttaa taaaatagat gcagatgcag aaacattaac aaaacgtttc ggtgttttag
     3421 gtgacacagt tgttattggc ctaattatcg gtattgtagt gggtattatg gcaggctatg
     3481 acgtagcagg aattggaaac ttaggaatta tgactgcggc agtgatgaag attatgccta
     3541 aaatggtagc aatgtttatg gaaggtttaa tgccaattgc agaagcggcg aaagaattta
     3601 cgaataaaaa gttaaatggt cgccaagtaa acattggaat ggatgcagcg ttaactgtgg
     3661 gtcatccaac tattatgtca acttctctat tgcttgtacc aatctcatta ttgctagcac
     3721 taattcttcc aggaaataaa gtattacctt ttggagattt agcattcttt gctttcgcca
     3781 tctgtttaat gattccttat tttaaaggaa atattgtgag atcattagta ggatgttcgt
     3841 tgtatgttgt tacaacatta tatatggcaa catggttggc accaattatc actgatgtgt
     3901 ttacattagc aagtttcgat gtggggacag caggattagt aactatgttg ttatgtggat
     3961 tatggccagt agggttgttt gttttattag catcttactt tggtgtaatt ggaataggtg
     4021 gattaggagt tgttttagta ggtgcttcta tctacatgaa caaagtgaag aaagcttaat
     4081 cataaaatta aaataagaaa gaagagatca atatgaaaaa attattagtt atttgtggag
     4141 caggtcatgc tacttctaca attgcagtag caaaattatc aaaatggttg gaagaagaag
     4201 gattaacaga tcaagtgaaa atttatcaat ctaaaattgc tgatgagcta aataaaattg
     4261 atgaatatga tgctgtagta agtacaacaa ttgtccctga tgtaattaaa gctaaagtaa
     4321 cgaatggctt gggcttatta acaggtattg gtacagatgc catttatgca gatgtaaaag
     4381 aaagattagg tgtttaatat gcgttttcat catgacactt tgactattga aacagtttca
     4441 gggcgtcctt cgtatcatga tattcgaaaa gaacttttag atacagttga tacagcaggt
     4501 attgagaatg gaatgttagt aatttcgagc ccgcatacaa cttgctcact cttttttgaa
     4561 gaaacgatgc atgacacaaa cttttttggt gatgattatt tacatgtaga catcaacaat
     4621 gtaatggaaa cgattattcc aaaaatgacg agtgaaaatc aatacaacag tccggggcca
     4681 aaacacattg attttggaac aagattatct gatcccaatt accctgcaga aaaatgggtc
     4741 atgctaaata ccgatgcaca tttacgttca tctatttatg gaaccaactc aatgacttta
     4801 attgttcaag aaggtaaact tttattagga gaaatgggcc gtgtctattt tgtcgattgg
     4861 gatcaactaa gagagcgaac tagaacaatc aatctcatga ttatgggaga ataaacgggg
     4921 gaatagagaa tgacaattgc tccatcattg ttaaatgcac ctatcgcaga agttaaagag
     4981 ttatttgaaa tcttaaaaga aaagaatgtt gattatttgc atattgatgt aatggatggc
     5041 tgttttgtac cagatatggc ttttggacca agtgttatta aagatattcg tccactaaca
     5101 gacgttgtgt ttgatgttca tttgatgatt gatacaccag aaaaaattgt cacaagattt
     5161 gtagaagcag gagcagatat tgttaccttc cacattgaag ctaccaaaca cgcaatgaag
     5221 gtcattcagt tagtcaagga agcaggagca aaagtaggga ttacttttaa tcctgcaaca
     5281 ccagtcagtt ttattgaacc agtattatct ttagtcgatc aagtattagt aatgacaatc
     5341 aatccaggaa cagagaataa gcattttatt caagagacag tagttaaaat cgaacagtta
     5401 gatgtaatac gcaaacaaaa tgattatacg tatgatattg aagtagatgg caagattgat
     5461 aatcaaacga ttaaagtttg ttctaaagca ggggcggata tttttgtatc aggcggtttc
     5521 atcttcaatg ggaaaaatac cccgcaagaa caaattgata aactaaatca atcattagag
     5581 gaagtgaagt aaaagatcat gaccaataaa gaccaaaata aaaactattt agaagcgatt
     5641 atcttagaat tacaaaataa ctcaaaacgt attaattctg tagagttaga acaatttagt
     5701 gagaaaattg ttcaagctaa acacatcttt ctagctggtg caggacgctc tggaattgcc
     5761 atgcaagcat ttacgaatcg cttaatgcat ttaggttttt cagtcagcct tgtcggtgaa
     5821 attagttcac cacattcgca acctggagat ttattaatta tctgttctgg ctcaggtgaa
     5881 acaggtagtt taaaaaattt agcggccaaa gcaaatcaaa gtggtgtaag cattgcttta
     5941 gttaccatga aaaaagactc gtcgattggt caattagcag attctgttct tgtattacca
     6001 ggtattacca aagatgaaaa tcaacgagaa gaagatactt tttcacaacc tatgggttca
     6061 agttttgaac aattagcatt tctcaccttt gatagtttag tgttatcttt aatggataaa
     6121 acaggtgaaa gctcagaaac gatgtttgct cgacatgcag attttgagta gtagatttta
     6181 aagataaaaa accattctct aaatgctaat tattcagcaa atatgagaat ggttttttta
     6241 tttgattaga cataacttaa taattcagta gttttgagcg taagcgtgtc atagaatggt
     6301 acctaaacac aaatagcccg atttgataca ctcaaatcag gttatttgtg gcttatatta
     6361 tttacagatt tcttgtatct gctgattcca tggcaaataa gcgcgtagcg cttcaggtgt
     6421 catcgaagac agattgggaa tctctgtaaa aagatgattt aaatatttgc ggatgtttaa
     6481 cccattcgca acagctgtct ggataatact caatataatt ccatttgatc tagcgccttt
     6541 taagctttta gaaaatagcc agttttttcg accgatcact aactctttga tggcacgctc
     6601 tgctcggtta tttgaaagtt ccaagcgtcc atcaagcaac acaatctgaa gtccgtcttt
     6661 atgattgact gcgtattgaa ccgcctttcc aagctgcgat tttggcaaat aagcaaaact
     6721 ctcacaccaa tgaaaaaatt cagtcatcac aggctgcaac gtttccttcc tcgctacaaa
     6781 cctttcttct gcgctaagct tattaaaggt ccgttcgatt cgaaacatct tgtcacagaa
     6841 gtctaatcct attttggcat gactttttgg ggacggttgt ttacccaatg cttcaaaaaa
     6901 ctttctgcga acatgcgccc aacaataaac attgtttacc ggcagctttc cataggccgc
     6961 gtaaccatca gtatgcaaga aaccgctaaa tgattctaaa aaactttttg gctcatcaac
     7021 ggaacgcgaa tttgcgtgct cgtagagcac aacttgtttt tcttcgcttt tacctgaagc
     7081 atataaccag taaaaggtct tttctttatg agtattcaat acccgatagc ttgtctcatc
     7141 cgcgtgtaag acctcctgat tgcttaattc ttgatgaagg caattgtaga ttggctctaa
     7201 aaccatttca cttaccttga tatgccaatt agtgattttt ttacgatcaa gagggaaacc
     7261 aagtgcatgc cattcttttt cttgtcgata tgccggcacc tttttaacaa atttttccca
     7321 aatactctgt gtcacaattg aagaggaacc tagactatta ttgatcaacg gtttaggaac
     7381 aggcgctttt ttgatttttg tttctcctaa tgcttcacat tctctgcaat gataggcatg
     7441 ttggtagatg acttgttttt ctatatgggc aggaacatac aatggctctt ctctaagcct
     7501 tgtcgcaccg atatcatgta aagtatgacc acagtcttca cacaaacaat cggcaccttt
     7561 taattcataa tgaataggaa cttcaggcag accttctaat gaaagtgctt tgagtccctt
     7621 gcgttttctg cgtttaaaag aagataccgt aatgggttcc tggctttctt gtccagtgtg
     7681 ctctggttca ttaaaagttg agtcgtctaa taaatcgatt tgcccatcta cgggtggtgt
     7741 ttcttttttt cgtccaaaca agcgtcgatt catttcagca atttgttctc taagaagagt
     7801 attttcctgt tgctggattt caagcaactg tgttaattgc ttgatttgta caagaagttc
     7861 agattccatt tttgtcattt ttacaccacc attctagcga ttttcttaca tctattatac
     7921 cattttatga caacgaaaaa cagacaaaat ccttgattta acaaggtttt cgtctaatat
     7981 atcgcacctt ttttcgtttc ttttagcgta catttttctt cgattgaaag gccagtcagt
     8041 aagacttctt ttctggaacg cggccattga aggtacccac tttcaaatct tttgtacatt
     8101 aatacaaatc cattttgatc ctagtaaaga gccttgaagc gatctttctt cgtaccgcaa
     8161 aataagaaaa gcgcttgatc gtaaacatca aggtcatatt cttctataac gaaagctgct
     8221 agtccatcaa ttccttttcg aagatctgtt tttccacaaa cgataaaaat atgtttcaat
     8281 gcagttgcat caatgagcat tggcattcaa ctcttttaac aaggtataca aaagatattt
     8341 atccattcca ttataaataa atatttcctt atcttccgat ttgattctgc aagctagttt
     8401 tggcttggtg tcaatttgcg atttttgagc cgcacttgaa aattgaactg gtacaatatc
     8461 ttttttattc attcgttttt ctccttctat atttgatagt ttaattatag aagaaagata
     8521 atcggcgtac gagatactat cctatgacac gcttacattt aatttaatat tttgcctcaa
     8581 attagccaca ctttttatag aactaagagg aaaaatgaag ttttcttcct attaatatag
     8641 ttgtttgaaa tcttaaatat agcgttttac gatgtaatgg gaagtatggt gaataaatca
     8701 actatgttcg tacgaagcat ttactcaact aatttaatcg aatctttcaa taaacaaatc
     8761 aagaaataca gccaccgcaa ggaacagttc caaaatgaag agtcgatgga acgtttctta
     8821 gtctcgtctt ttgatactta caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa
     8881 caggccgaag gcgagctcga acaaatgctg agtcaaccga tggagaatta gaaacaatct
     8941 acagtaggga agaaccattg acacaaaatt attgacgctc ccaactaaaa gtgtcaaaat
     9001 aatgatgaaa tcatttagtt cttataaatt agaaaagaga aaataaatat tccatatcta
     9061 ctttattgga tccgtaacat gactaaattc tgaatacttt ttaaagctta tcatttggta
     9121 aaactgaata taagttaatt atatagactg aaaattttga attttcagaa tagaataact
     9181 taaaagtact gacaaaattt tttaaagggg caatattaat gttctgagat aatcaaatcc
     9241 taccgaaaat atcaaaaatc caatgtgaca caatcagatt gtgtctcatt cgagggaatc
     9301 acacaatccc acgtggctct aggcagaatt gaatttttgc ttggggcttt ttccttatat
     9361 tgattttgaa tcagacttat tatatgttat aatgcaatta agtatcattg gagagggcga
     9421 agaaaatgaa gacggtagaa cctattcgag acaaaaaaaa gatcgatgcg atgaaggcaa
     9481 tcttggcttc gggaaaatat ggccaacgaa atttggttct tttttcgatt gggatcaaca
     9541 ccgcctatcg catttctgat ttgcgtcaat tgaagctggc cgacgtgctg gaaatttcac
     9601 gcggtcgcgt ggtggtcaaa gatcgattag cgatgaagga acaaaaaaca gctaaacata
     9661 attcggtcta tatttccaac aaattgcgaa aaacgatttt ggagtacgtt caacaggaat
     9721 ttcctgatca actccttcag caagattttg acggttattt gttccctagt cgaaaaggga
     9781 cgaatgaacc gctcaaccgc caaagtctgt ggcgaatcat tcatgatgct ggcacggcaa
     9841 tcggattgaa agacattggc ccacattcca tgcgaaaaac gttcggttac tttctctata
     9901 aacaggggac caaaacagaa atcattcagt ccttgttgaa ccattcttct cagcgcgaaa
     9961 cattgcggta tattggtatt acacaagaag acaaagatac agctgtaaaa agcttagatt
    10021 tataatataa aagttaagtt taaacatgga tagttttaaa ttagtagatt gagtgttggg
    10081 aggaaagaat gagtacatta tatattatag gaaacggttt tgatttaagt catggtttaa
    10141 aaactagata cactgatttt tcaaaatggg ttgaaaaaag tcatagtgaa atattcgata
    10201 aaatagacac aatgataaat gaaaataatg aggtgagaag tacagctgat gataagatag
    10261 gttggtttaa ttttgaaagt agtttgcatg agttaattca aagtccagtc tttgaagatt
    10321 atgtagaaga gtctaaggat tatctcatag gttatggaca tgaagattgg tcagattctg
    10381 cccatcatga ttttcaaaat atggtttatg attatgttgt ttctctagaa gaattacaac
    10441 aacttttcaa ggaatggata cgcaaagaaa tacagccgac aatagaacat aaaattccaa
    10501 aataccaatt ttcgtccgat gtactattct ttacattcaa ttatacagat gttttggaaa
    10561 ttctatacaa gcaaccgaaa gaaaacatat atcatattca tggcagttat gacgatataa
    10621 taatcggcca ctccgagaat tttgacaact ttataggaga
//
LOCUS       DASHWW010000082        10156 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.082, whole genome shotgun sequence.
ACCESSION   DASHWW010000082 DASHWW010000000
VERSION     DASHWW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.082"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(560..1600)
                     /locus_tag="U2R64_002462"
     CDS             complement(560..1600)
                     /locus_tag="U2R64_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEM8919246.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="U2R64_002463"
     CDS             complement(1949..2275)
                     /locus_tag="U2R64_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919247.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3065)
                     /locus_tag="U2R64_002464"
     CDS             complement(2262..3065)
                     /locus_tag="U2R64_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8919248.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3418..3708)
                     /locus_tag="U2R64_002465"
     CDS             complement(3418..3708)
                     /locus_tag="U2R64_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEM8919249.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3844..4023)
                     /locus_tag="U2R64_002466"
     CDS             complement(3844..4023)
                     /locus_tag="U2R64_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919250.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4020..4370)
                     /locus_tag="U2R64_002467"
     CDS             complement(4020..4370)
                     /locus_tag="U2R64_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919251.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4363..5688)
                     /locus_tag="U2R64_002468"
     CDS             complement(4363..5688)
                     /locus_tag="U2R64_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEM8919252.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6138..6752
                     /locus_tag="U2R64_002469"
     CDS             6138..6752
                     /locus_tag="U2R64_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919253.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6917..7921)
                     /locus_tag="U2R64_002470"
     CDS             complement(6917..7921)
                     /locus_tag="U2R64_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919254.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(8380..8637)
                     /locus_tag="U2R64_002471"
     CDS             complement(8380..8637)
                     /locus_tag="U2R64_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEM8919255.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8630..8899)
                     /locus_tag="U2R64_002472"
     CDS             complement(8630..8899)
                     /locus_tag="U2R64_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEM8919256.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9030..9209)
                     /locus_tag="U2R64_002473"
     CDS             complement(9030..9209)
                     /locus_tag="U2R64_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919257.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9590..>10156)
                     /locus_tag="U2R64_002474"
     CDS             complement(9590..>10156)
                     /locus_tag="U2R64_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919258.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3102 a         1855 c         1457 g         3742 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aacgaatgaa gcaggtaatg attttattct acgttgtcgg gttatccagc ttgcaaccgt
     3601 tccttgtggg taggcatata actcacaaaa ttgttctaca gtgattccta aattcttgat
     3661 aatgtaaaca ttgatcgggt gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc
     3721 tactttcttt tattattgcg tttgcaataa tagtttaaca cacgcattat tctagtatct
     3781 actcctattt gtaaaaacaa aaaaggattc atagagataa ctctatagaa tccgtaaaat
     3841 accttatata tataacggga agatataaaa cctaaaatta tgataacctg ctgcagcttc
     3901 tacatagaaa gagaagcgct caacaccaac ctcatttatc aaacgttggc cataacccca
     3961 aatctcttct gatagctgat caaaggttat atactttagc tcatattgct ggataatgtt
     4021 cattctaatc gactccattt attatcctgg taaaattcga tatgacgtat ttcgtcgtag
     4081 tgaattttgt cttttccaac gtagatcccc agctcatcac tacctaagat cttgccaatg
     4141 atatcttctg gatagtatcc ttcagcgttt cgttcttctt tttgaataga tactgatcta
     4201 ttttttatga ctgcagcgtt caatacttcc gcaatctctt cagtcgtcat ttgttctttt
     4261 gctaaatttt gactggttcg ttgttcattg tcggcatcaa tttcttcagt atgatcagat
     4321 aaataaaacc ctgcccactt taaacgtcca cgatcattgt aatcaatcat ttttaattcc
     4381 cccatttccg cccgcatgac caccaacaag tgtgcttcta gtaatgcttc tagcgccttc
     4441 taacattgaa gaagcatgta caatcgacgt aaaaccatat ttttgccgaa tcttgtcaat
     4501 aattttatct aaattttctt cgtcaatttg cttttgtgga tcactaaata aatccagctg
     4561 aagcgaatcg gtgtacacaa gcttgctata ggttattcca acatgcctta cttcttgtcc
     4621 ttcataatac ttatcaaaca agaaaagaca ataattctgc aattcctttg tattatctgt
     4681 gatagggatc ttcatctggt gtgaaaaccc tggtctcgtt tctaagatcg acgtgccaat
     4741 gtgtaaatgg acacaacctg ttttacagtt atgctgccta atgcgtatcg ctacttgttc
     4801 cgccatttct tttaccacca gctcgatttc atttcttcta gtataatctc gtggtaacac
     4861 ttgtgaattt ccatatgatt tttcctttgt cggttctggt gggattgcta tatctgttcg
     4921 atcgatccca ttagcatgga agtacagctg taagccaatc acacctagtc tattcttaat
     4981 cgtataagga ttccagttag caagatctct aatgctcata atccccatct gattgagtct
     5041 ttttttcatt cgagagccaa ttccccaaaa gtccgtcatt tcaggaatat tccatacttt
     5101 ttcaggaacg ttttcgtacg tccattccgc aacaaatcct tcattatgct ttgcttcgtt
     5161 gtctaaggct agtttagcca aaagaggatt atctccgaca cctactgtag caatcaatcc
     5221 tagctcttct ttaatattct cctggatcat ttgagccagc ttctttctcc gttgacttcg
     5281 tgttccttca gtcgtaaaaa gattcagtga tcgggtcact tttaagattg attcatcgat
     5341 cgagtaaatc agtagatctt catcagccac atatcttctg aaaatattat ttacctgcat
     5401 atttcgcttg atatataggt tcatacgtgg tggaacaacg tgtagtgttt taggaaatgg
     5461 ttgtggtaag tcacgtggtc tactcacatt tgtaatacca taccgctttt ttgcttcagg
     5521 agaagaagct aatatcaatc ctgaaccagt attatcagct cgactcataa caacaagttc
     5581 tgttgttaat ggatctaaat ttctttctat acattcgaca cttgcgtaaa agcttttcat
     5641 atcgattaaa aagtaatcat ttactggctc ttttgaataa tccatcataa ataacactcc
     5701 attctttcac attatacaaa catatgttcg atattgtaaa gaagaaatag ctaaatacat
     5761 aaaaaaagaa gcataggtat gctatcaccc tgcttcttct tttgatttgt atgatcaatt
     5821 tattctatca ctttactaat taatttgaaa atctaataaa aactctcact ctaaaagagt
     5881 gagagactgc aaattagagt acggactttt ttggagttcc gttctttaat attaacaaat
     5941 gaataaaatc cttacaacat ttgagaataa gttatcagta gacacttaca aaaaattctc
     6001 atactatttc ctccatcatt agtttttgtc tatataaggt ttaccctaaa tagacactgg
     6061 tataacattg aaaaatatgg cttcctcgtg tatgattagg gtgtatttta aatagttgca
     6121 gaaagtaggt aaaagttttg agagttgcat acatacgtgt ctcatcgatc gatcaaaatg
     6181 aacaacgcca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc atcgagaaac
     6241 aatctggcgc aacgattact catcgacctg ttttccaaga agcattagat tacgtccgag
     6301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattat gacgagatca
     6361 tcgcttcagt caattacttg aagaagaaaa atgtgaagct gatcattact agtttaccga
     6421 tcatggctga agcaattggc aatcctctcc tggataaatt cattaaggat ctgatcatcc
     6481 aaattttggc catgatcgct gaacaagaac ggactgaatc gaaacgtcgc caggcacaag
     6541 gaattaagat cgcaaaagca aacggcgtct acaaagggcg gcccaaatta tacagtgcag
     6601 acgcaaaaga tccccaacgt cgccttgttt acaaaagcat cgttgaagat cttaaaaatg
     6661 gtgttgcgat tgctaagatt gctaaagact acaatgttac gagacaaacc gtgtatagaa
     6721 taaaaaaaga cagcatggtc aatgacaaat agttgatcat gctgctttta ttatcttctc
     6781 atctttaatt tcctacatat aattactatc tataaaatta agtcttactc agaacagata
     6841 aagcataaaa ttccaacaaa ccatttttta cttaactaaa taaagagtct gttaatataa
     6901 tcttcactta tttacgttaa tcccctactg tatttgttgg ttccttatct atattttcta
     6961 caaaatcctt attatcttgt gatttagctt cgtataattc tttgtatgtc gacacattgg
     7021 ttatactaat tcctatagct agttcttgag actctacttt tctctctagc tcctttgaca
     7081 aagtgatttg agatttattt ggttccgttg gagtcaattc tatagattct tcataaaaat
     7141 ctctatacat aaagctatca ttaattttat aaaaaaaatt aaatgttttt agcactgcca
     7201 tataacattc aaaacattct tctatagttg gtttacttcc ttgaggagaa tgaaccaatt
     7261 tattacgttt ttctatgaaa tttttaattt cctttcttat ttctttcgga aactcaatat
     7321 taaagtaccc tttaaacatg ctccctaata atttgtctac agggggagat tgtaaattct
     7381 caaatattag agttaaatca ggtttctctt gttgataaaa ttcctttacc cctatttcac
     7441 aggctgtaat tatcgaaata aacctatctc tagtatttga tatattttta cttcttttaa
     7501 ggagtataag agaaaagggg atactttcgt gtccatgcat gtaattaact aattgttgag
     7561 cttcagaagt tatatctcta attatatagt taacggaatt aggaagtgtc tttaactcta
     7621 atgaaatttc tatccaatta ctatcttcta atctgtatat gctcgaagta taatttgatt
     7681 cgtcagcaag catcgctaca tcccaaacac tgatcataaa atcttttaaa cgttcaatca
     7741 tttcagcaat attgctaaaa tcagctaatt tttctttaga ataaaaaaaa acatttatat
     7801 cagaatcaat aaattctatt ttttttatta ctatatcgtc atcattatct tgaccattta
     7861 tgtttattgt tccctgagtg gggagtactt ctttcaaatt caagttaaat ttatattcca
     7921 ttacttctcc tccaatatat aaaaattact taactgtatc caaatttaat atgtaaataa
     7981 atcattaatt tttagctaaa ttctatgaga agtttatttt tgttgttttt gctaattaac
     8041 taaaactagt acaaaaaatt taaaatagat tattaaacct attgcttatt ctattcagtc
     8101 atatatataa gcgtcatcct ttagtaacta acatcccaca ctacaatagt attataacat
     8161 atctattcaa cttcaaattg ttgaaattta agccatttat atttactttt cctcaacttt
     8221 agaaatgatt ttactaacct tatatccgta atacgcgtaa caaacacatt cattaataac
     8281 aatcaacact aagctatatt agctttttaa atgactaggg taaataaaat aaggatcaaa
     8341 aacttttaag tttctgaccc tttccttact tccgattggt taatagtgat cttttgcaga
     8401 ataaataaat atcgtttcat tttcaactct atatatcagt ctatgttcat ctgtaattct
     8461 tctggaccat tttccagata aatcatgctt taatggctca ggttttccta atccagcaaa
     8521 gggggaacga tcgatatctt ttattaactt gttaatcttt tttatattgc ttttgtttcc
     8581 ttgctcatgc caataaagat aatcatccca agcatcatca gaccaagcct taatcatcag
     8641 attcaacctc gattaagtca tgtgttttaa atgcaccttt ggagaattgt tcatctcctc
     8701 gacgaatttt ttccatgacg taattattag aaagtgttct caacgtttct tgcatagaat
     8761 cataatctct ttttgataat acaacaactg tatcttctac atctttactt gttacaataa
     8821 gtgtttcagc atcctcatta acttgtttca tataactacg taaattttgg cggaaatttg
     8881 aataagctac tgcttccatt cctttcaccc cttatttatt tctataaaac aattgtacat
     8941 tatattgtac aattaagcaa atgattaata ttctaacttc ttataattaa aagtgctatc
     9001 acttttagtt tttaggataa aaagtgacgt cactttttga gtgctggtac ctcaaatcct
     9061 gctttttctt gggcaatcaa taaatctaac gcaatacaca taatcctgga ttcacttttg
     9121 ccgtacttct gctttagttg ctgcaattct ttttgtctct tttcatccaa cgtaacgggt
     9181 aaccgtttat ttcctattgc aattggcatt agtactctct cctttcatcg aaataaccct
     9241 atgaaaaata tggctgcaat catcttgaat agtagactca caagggctaa tacaaagcgc
     9301 caaaagatca aacaaaatac cagtattgcc aaaaatacta cgaagtttaa atgcacagct
     9361 gcagcatggc gcataagtat ttcgccaaca aataggacta acaatagagg aatgatttta
     9421 ttcatatgga tctccttctt tctcttaggt tatcgggtgt tgcccgctta tttcgcacca
     9481 cctaagcggc gggggcggtt ggagcgattg gtgcgaaata agaaccattc ccttagttac
     9541 taggtttttt gtccttattt cacacattct cacttttcgg tataaatgat tattgccttt
     9601 ttttcctttc aaatcgttga tatggcattc gtttacggtc aagttcattt tggatttctt
     9661 ctgtatcgtc gtaagtatag gtgtctaaaa aatcagttaa agtcgtgtac cagtcgtcgc
     9721 ctgggttatc tacttcttct acatattccc tcaaaaatgc ttcgggtaca gcgagttcat
     9781 aatccattcc cattaacacg atagattccg ttccacacgt caaaaatcta gtaaatacaa
     9841 ggtaataatc gtctatcgtc gcatctttgc tgtttagctc ttccatttct tcttccatta
     9901 attccatgct ctcaaaaatt gaataatatt ctgattctga gtaatagtgt ttcctgcaaa
     9961 tcgtgtagct gacaaagttt tcgaccagct cactcctttc taggtaaaca ttcatgatgt
    10021 atttttctgt ttctagtcgt agaagctccg ttcctttttt taccgtttca ggacgacgtt
    10081 tatacacgtc taaacgatta tggctgactg tgaccttcgt ttgactcgtt tcactttcca
    10141 aatacaattg ttcttc
//
LOCUS       DASHWW010000083         9964 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.083, whole genome shotgun sequence.
ACCESSION   DASHWW010000083 DASHWW010000000
VERSION     DASHWW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.083"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            8..81
                     /locus_tag="U2R64_002475"
     tRNA            8..81
                     /locus_tag="U2R64_002475"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="U2R64_002476"
     tRNA            101..173
                     /locus_tag="U2R64_002476"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="U2R64_002477"
     tRNA            201..274
                     /locus_tag="U2R64_002477"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="U2R64_002478"
     tRNA            288..361
                     /locus_tag="U2R64_002478"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="U2R64_002479"
     tRNA            385..474
                     /locus_tag="U2R64_002479"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="U2R64_002480"
     tRNA            487..560
                     /locus_tag="U2R64_002480"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="U2R64_002481"
     tRNA            579..654
                     /locus_tag="U2R64_002481"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="U2R64_002482"
     tRNA            656..726
                     /locus_tag="U2R64_002482"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="U2R64_002483"
     tRNA            740..813
                     /locus_tag="U2R64_002483"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="U2R64_002484"
     tRNA            838..925
                     /locus_tag="U2R64_002484"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="U2R64_002485"
     tRNA            947..1018
                     /locus_tag="U2R64_002485"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="U2R64_002486"
     tRNA            1041..1130
                     /locus_tag="U2R64_002486"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="U2R64_002487"
     tRNA            1143..1216
                     /locus_tag="U2R64_002487"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="U2R64_002488"
     tRNA            1235..1307
                     /locus_tag="U2R64_002488"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="U2R64_002489"
     tRNA            1311..1383
                     /locus_tag="U2R64_002489"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="U2R64_002490"
     tRNA            1388..1458
                     /locus_tag="U2R64_002490"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="U2R64_002491"
     tRNA            1471..1544
                     /locus_tag="U2R64_002491"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="U2R64_002492"
     tRNA            1556..1627
                     /locus_tag="U2R64_002492"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /locus_tag="U2R64_002493"
     CDS             1893..3086
                     /locus_tag="U2R64_002493"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEM8919259.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="U2R64_002494"
     CDS             3216..4688
                     /locus_tag="U2R64_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8919260.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="U2R64_002495"
     CDS             4771..5559
                     /locus_tag="U2R64_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEM8919261.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="U2R64_002496"
     CDS             complement(5626..6294)
                     /locus_tag="U2R64_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEM8919262.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="U2R64_002497"
     CDS             6409..8121
                     /locus_tag="U2R64_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919263.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="U2R64_002498"
     CDS             8124..9896
                     /locus_tag="U2R64_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919264.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2900 a         1781 c         2278 g         3005 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggca
//
LOCUS       DASHWW010000084         9897 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.084, whole genome shotgun sequence.
ACCESSION   DASHWW010000084 DASHWW010000000
VERSION     DASHWW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.084"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            372..3179
                     /locus_tag="U2R64_002499"
     CDS             372..3179
                     /locus_tag="U2R64_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8919265.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3370..3861
                     /locus_tag="U2R64_002500"
     CDS             3370..3861
                     /locus_tag="U2R64_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8919266.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3964..4953
                     /gene="manX"
                     /locus_tag="U2R64_002501"
     CDS             3964..4953
                     /gene="manX"
                     /locus_tag="U2R64_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEM8919267.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4986..5789
                     /locus_tag="U2R64_002502"
     CDS             4986..5789
                     /locus_tag="U2R64_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEM8919268.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5810..6724
                     /locus_tag="U2R64_002503"
     CDS             5810..6724
                     /locus_tag="U2R64_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEM8919269.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6807..7181
                     /locus_tag="U2R64_002504"
     CDS             6807..7181
                     /locus_tag="U2R64_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEM8919270.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7320..7565
                     /locus_tag="U2R64_002505"
     CDS             7320..7565
                     /locus_tag="U2R64_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8919271.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7737..8801
                     /locus_tag="U2R64_002506"
     CDS             7737..8801
                     /locus_tag="U2R64_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEM8919272.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9047..9472
                     /locus_tag="U2R64_002507"
     CDS             9047..9472
                     /locus_tag="U2R64_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8919273.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9465..>9897
                     /gene="nusB"
                     /locus_tag="U2R64_002508"
     CDS             9465..>9897
                     /gene="nusB"
                     /locus_tag="U2R64_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEM8919274.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKE"
BASE COUNT         3224 a         1624 c         2189 g         2860 t
ORIGIN      
        1 aataaaagtt gtagtggagg ctacgaagtt tactttgtct ttttacactt aatatttttt
       61 tgccaatttg gaatcaggat gttttgataa ctatcgtttt caattgatgg aagctatatt
      121 gtttgctatc agtgaaataa ttatatggta aacagtgttc tttttcttgt ttccattata
      181 aaaatcgtat cgggattttt cgttctttta aattgaacat ttctatctat ccgcgtgtta
      241 tcaacaaaac aaaatcaggt aaatagttga cgaaacagaa ataaatacat agtattatgt
      301 tttgaagcct aagtacaata gtctatagaa aaggagcgat accattggca aaacgcattg
      361 accgaattta tatgtatgtc aaagaaaaaa ccgctcattt aacaaaggca gaatatgatc
      421 aaggagtaac aacacaggaa attgctgaag tgttagggat tcagcgaaca aatagcagta
      481 aagatctgaa tcagctagtg cgcgaaggaa aactgataaa gacagacgga cgaccagtac
      541 gttacatata tcaaacactc gttacgcacg taaagccagt tacaaaacat gtagtcagtt
      601 acaaagaaac gccggtctct gaagaaaaaa atacactcca aatagatact aaggatatct
      661 ttgcaaaaat cattggagct aacggcagca tgaaaaattc agtggaacag gcaaaagctg
      721 cgattttgta tccgccaaga ggattaaatt gtttgattac aggacctacc ggatcaggaa
      781 agacttattt tgcacacgcg atgtatcatt ttgcaaaagc gcatcatgta atagatgagg
      841 aaacggaact gattgttttc aattgtgctg attatgccaa taaccctgag cttttgatga
      901 gtcatttatt tgggtacgca aaaggtgctt ttacaggcgc agatgaagaa aaaatgggga
      961 ttatcgatca agcggatggc ggtatgctgt ttttggatga gattcaccgg ttgccgcctg
     1021 aaggtcaaga aatgatcttt tactttatgg atcatggaac ttacagtcgt cttggggaaa
     1081 caacgaaatc ccatgaagca aatgtacgga tcgtaggtgc gaccacagaa gacccaggtt
     1141 cttctctatt agaaactttt gttcggcgta tcccaatcaa tatcaaactt ccggcttttg
     1201 aaaaacgtcc tgcaaatgag aaagtcgatt tagtaaaaat catgattgcc cacgaagcaa
     1261 accgcacgca gcgaaagatt tctttgacag aagatgtagc aaaagcattg atcggcagtg
     1321 tgacctatgg aaatatagga caattgaagt caaatatcca gttagtatgt gcacgaggat
     1381 ttctaaatca tatgcaatca cccgaaatct cgatcacaat cgatgatttg acagaaggga
     1441 ttcgtagcgg attgattcaa ttagcaagca accgcagtgc aatggcagag ctttctaaaa
     1501 tattggagcc aaagataact gtagcaccaa atgatacgat catgaaaatc caatcggact
     1561 cctatgagtt accttataat ctatatgata tcatcggaga taaagcagct ttactgaagt
     1621 cggatggttt ggatcaagaa gcaatcaatc atttcatttc tacagatatc aacatccatc
     1681 tgaagtcttt ctataaagac catggttttt cttttaatgc agacagcaaa ttagcagaat
     1741 ttgtagatcc gaaaatcata gaagtgacca atcagattta tgtaatggtc aaaagatctt
     1801 taccatatga gtttcagcaa aactttattt atgctatgag cttgcatatc agttcttttt
     1861 tgaaaaaaat caacttagga gaagaacggc atacgaatga taacatccgt gagatggctt
     1921 ttgattttcc agatgaatat gctgttgcga aagaagtgcg tagttatatc gaaacgtatt
     1981 ttcaagtgga gattccagaa agtgaagact attacttgac cgttctactc gtctcgttac
     2041 gggcaaatca agcaagcggc agaatcggtg tagtcgttgc agctcacgga aacagcacag
     2101 caagcagtat ggtccaagtt gtccaacagt tgttagatgc agagaacgta cgagcagtag
     2161 acatgccttt ggatatggat ccgaaaacag cattggaccg aattgaacgc aatgtacaag
     2221 aagtagatga aggaagcggg gtcatactct tagtagatat ggggtccctt gcgtcgttta
     2281 attcgcaaat tcaaagagac actggaattc cagtacgtac tgttgatatg gtaacaactt
     2341 ctctagtttt ggaaactgta cgaaaggtct cagtattagg gacagatcta gatatgttgc
     2401 atgaatcatt gaaaaatttt cgaggttacg cagaaatatc ttctgtagaa tctgttcagg
     2461 aagcaaaacc tattcataag aaaaaagctg ttttggctat ctgcgcatct ggcgaaggta
     2521 cagcacaaag aatcaaagaa ttgatcgaac gagcggtaaa caagcgtcaa gaaacagaat
     2581 tagaagttct agctttgtcg attgtggaag tgaaagaaga actgccagtt atccaaaaag
     2641 aatatcagat catagctact actgggatta ctgatttgaa tatccaagcc ccatttattc
     2701 ctttagaacg ttttattgat caaaatatcg aagtcatttt ggatcagttg ctgatggaat
     2761 cagaattgga ggaaactgaa ttcatctccc tagatgaaga gtcagctaaa aatacgtgtg
     2821 ttgagtttat ctctgataac ttcatcttta ttaatggtag taagttaatc gatccaatgt
     2881 ggcaattttc tacacaaatc tctcagacga cgggaatcgg cgatgaagaa tatggattca
     2941 aaatcaacct agtgatgcac acagcaggaa tgatcgaacg tattattcgg aatgaaccat
     3001 tgactgtgga agaaaacgaa ttgacaaata caacgaatga tcctctttat agccaattgg
     3061 cagcctcagt tgttctgttg gaagatcaga taaaagtaaa agtgccgata gaagaaatgt
     3121 attatctgct acgtctagtc cataatcagt tagataaaaa agaatacact gtgccatgaa
     3181 tacacaaaaa cgatacactt ttatagtgta tcgtttttgt gtattggtta agaatccttt
     3241 aaattcaatt agtgtatcgt aaaaaagttg gcacgctttt tgcttatagt agtgtgtgct
     3301 aggaggtggt tgttcacaca gaaatgatag gggtttctgt gaagtagtga ggaagaagga
     3361 gttttgcaga tggatattcg attggcacgt atagatgatc gtttaatcca cgggcaagtc
     3421 gcaacagttt ggtcgaagca aacaggtgtt gaacgtatca ttgtgatcag cgatgtagtc
     3481 gctcaagata aattgagaaa gtttctacta aaagaagctg caccgccggg gatcacagca
     3541 aatgtaataa ccgtgcagaa aatgattcaa atctatcata gtggattatt atcacgagca
     3601 aaagtgatgc ttttattcac caatccccaa gatgttgaag cggttgtccg ctgcggtgta
     3661 cagttgaagt cgttgaatat cggcggtatg agttttactg aaggcaaatc aatgattacc
     3721 aattttgttt cagtaaatca acaagatatt gattcctttc gttacttgaa cagtcaagaa
     3781 gtggagttag agattcgaaa agtacctgct gacaggaaaa tccttttgat ggaactacta
     3841 gcgaaaatca aaaaggtgta gcaagaatgg ttgttggaaa aggtcaaata attctgttgt
     3901 aatggttagc aattattaat atttttgaat ttgttacaac aaaagtaaat aggaggtata
     3961 aatatggtag ggattatcct agcaagtcat ggacaatttg ctgaaggaat cttacaatcc
     4021 ggttcaatga tctttggcga acaagaaaac gtcaaagccg tgattttgaa accaagtgaa
     4081 ggtccagatg acttgagagc caaattggaa gaagcggttg cttcttttga taatcaagac
     4141 gaagtgttat tcttagttga tttatggggc ggaacaccgt tcaatcaatc aaacacatta
     4201 ttcgaagagc acaaagataa atgggcaatc gtcagcggtt tgaatttacc aatgttgatt
     4261 gaagcctacg catcacgctt ttcaatggaa tctgctcatg aaattgcagc acacatcatt
     4321 gaaacagcaa aagacggtgt aaaagtaaaa ccggaagaat tagaaccggc agaagcaccg
     4381 aaagcagcag ttgaagacgc acaacctaaa ggagcacttc cagaaggaac tgtggtcgga
     4441 gacggaaaaa tcaaatatgt attagcacgt gttgactcac gtctgttaca tggacaagtt
     4501 gcgacagctt ggacaaaagc agtgcaacca aaccgtatta tcgttgtttc agatgcagta
     4561 tcaaaggatg atctgcgtaa gagactaatc gaacaagctg ctcctccagg tgtaaaagca
     4621 aatgttattc ctattagcaa aatgatcgaa gtagcaaaag accctcgttt tggaaatacc
     4681 aaagcattgc ttttatttga aaatcctgaa gacgtattga cagctgttga aggtggcgta
     4741 gacatcaaag aattaaatgt tgggtcaatg gcgcattcgg tcggtaaagt cgttgtaagt
     4801 aaagtattgt ctatgggaca agaagacgtt gaagcgtttg agaagcttga acaaaaaggt
     4861 gtgaaattcg atgtacgtaa agtacctaat gattcacgcg ataacatgga tgatattttg
     4921 aaaaaagcaa aagctgaatt agcaaaagcg taataaataa tattaaaatt tataggaggc
     4981 ttatcatgtc tattatttca ataattttag tcgtattagt tgcctttcta gctggtatgg
     5041 aaggtattct tgatgaattt caatttcatc aaccactagt ggcatgtaca ttgatcggtt
     5101 tagttaccgg taacctcgaa gctggtatcg tacttggcgg tacgcttcag atgatcgctt
     5161 taggttgggc aaatatcggt gccgctgtag caccagatgc tgcattagca tcagtagcat
     5221 cagcaattat tttagtttta ggtggacaag gtgttaaagg tgttccttct gcgatcgcga
     5281 ttgccgttcc tttggctgtt gcagggttgt tcttaacaat gatcgtacgt acaatcgctg
     5341 ttccaatcgt tcatttgatg gatgcggctg ctgaagaagg aaacatccgt aaggttgaaa
     5401 tgtggcacat cattgctgta tgtttacaag gggttcgtat cgcggtccca gcagcagcgt
     5461 tgctatttat cccagcacaa actgtgcaat cattccttga atcaatgcca gcatggttaa
     5521 cagatggtat ggctatcggt gggggaatgg tcgtagctgt aggttacgct ttggtaatca
     5581 acatgatggc tacaaaagaa gtatggccat tcttcgttat tggtttcgtt gtagctgcaa
     5641 tttctcaatt aacattgatt gctctaggtg ctttaggtgt tgcattagct cttatttact
     5701 tgaacctttc taaaatgggt ggttcatcaa ataatggagg cggaagcaac tctggtgacc
     5761 ctttaggcga cattttgaat gactattaat cttgaaggag gaaaataaaa tggcagaaga
     5821 aaaaatcaaa ttatcaaaaa aagatcgttt agctgttgcg tggcgctcta ccttcattca
     5881 aggttcatgg aactacgaac gtatgcaaaa cggtggctgg gcattttcta tgattccagc
     5941 aatcaaaaaa ttatacaaaa caaaagaaga acgttctgca gcattaaaac gtcacttgga
     6001 attctttaat acacacccat acattgcttc tccaatttta ggggttacat tggctctgga
     6061 agaagaacgt gcgaatggcg cgcctgttga tgatgtagcg attcaagggg ttaaagtagg
     6121 tatgatgggt cctttagctg gtgttggtga cccagtgttc tggtttacag tacgtccaat
     6181 gctaggtgca ctaggtgctt cattagctat gggaggaaat atccttggac caatcatctt
     6241 cttcttaggt tggaacatta ttcgttgggc attcatgtgg tatacacaag aatttggcta
     6301 caaagctggt tctaaaatta ctgatgacct ttctggcgga ttgttacaag acgtaacaaa
     6361 aggtgcttca attttaggga tgttcgtatt agctgccctt gtacaaagat gggtatcaat
     6421 caaattctta ccagttgtat caactgtaaa attagataaa ggtgcttaca tcgaatggga
     6481 taaattgcct tcaggtggtg aaggaatcaa gagtgcattt gaacaagtta ataatggctt
     6541 agccctttct cctgaaaagg taacaacatt acaagacaac ttagaccaat tgattcctgg
     6601 tttagctgca ttaggattaa cattgttatg tatgtggttg cttaagaaaa aggtttctcc
     6661 aatcgttatc atccttggtt tattcgtagt cggtgttgtt ggacacgtca tcggactttt
     6721 ataatccata aaaatatagc tcgggcgttg tcccgagctt tttttatata gtatactgtt
     6781 cataaacaaa tatctggagg gagaaaatgg ttcaatcaat caatacaaaa gtagacttgg
     6841 taattgatgc tacttcgttt acgggtctga cagattacgg gcaaatcatg ataggtgata
     6901 atggttttga gttttaccat gcgcgagata gacgcaaata tatccaaatt ccatgggaag
     6961 aagtggatta tgtactagca tcagtcatgc taaagggaaa atggattcct cgatatgcca
     7021 ttcaaacgaa aaaaaatggt acatacacat tttcttccaa agaacctaaa aaagtgcttc
     7081 gtgcgatcag agaatatgta gatgaagata gaatggtaca atcattgagt ttctttgatg
     7141 tagtgaaacg tggtattcgt agtatgttta aacgcaagta aaaaataaag aaaacttcta
     7201 agaggaggtt ttctttattt ttttactttg cagaagaaaa tatgaaatag caaaaccaat
     7261 tatttgtccc ctttaaatcc catatgctaa aattgattag caaagaagga ggttatatta
     7321 tgagttggtt atggacattg attgttggag ccgtgatcgg agcaattgca ggtgcgatca
     7381 ccagtaaagg aaattcgatg ggctgtgtaa cgaatatcat tgctggacta gtcggttcaa
     7441 gtattggaca agcgattttc ggcgaatggg gaccaaaagc tgcaggtatg gcacttattc
     7501 catctatttt aggcgcagtg attttggtag cagttgtctc atttttcttt ggaaaacgat
     7561 cataagtttt tacaaaatag taaactaaaa ggagttgcag cgagactgtg actccttttt
     7621 ggctttattt atttaaaata aaaagaagtt ttccggaaat ttttatttaa ctgtcgtgta
     7681 cgaagaaaag tttgctataa tggaaaaaag cgtgcaaaga aagagggagt ttcattatga
     7741 tgctacgtgt agaaaaattg cgcaaaaaaa tgcaagaaga aaatttggat tcatttttgg
     7801 ttaccagtcc gtacaatctt cgttacttaa cgaactttac aggtacgaca ggattagctg
     7861 ttattacttt ggaaaaagca ttttttatta ctgattttcg ttataccgag caggcggcag
     7921 cgcaggctca agggtttgaa attattaaaa atgtcggacc tatttttgat gaggtagcaa
     7981 acttagtacg caaagaagaa ctgcactcat tagcttttga ggaaacaaca gtctcatttt
     8041 tagaatattc ggttttagaa gaaatcatcg atgcggaatt agtacctgtt tcacagatga
     8101 tcgaagaact cagagaagtg aaagatgaag aagaaatcgc tattatcgaa aaagcatgtc
     8161 atattgcgga tatggcatat gatcacatcc tgaaaatgat ccaaccgggc atgactgaga
     8221 ttgaagtcgc aaatcaacta gacttttata tgcgttctct tggcgcttca ggtgtttctt
     8281 ttgatacgat cgttgctagc ggattgcgtt cggctatgcc gcatggtgta gcaagcaaaa
     8341 aaatcatcga acaaggtgac ttgatcacat tggactttgg ttgctattac gaagggtacg
     8401 tttccgatat gacacgtaca ttcgctattg gtgatcctgg ggaaaaatta aaagaaattt
     8461 atcaaatagt cttagatgct caattagcag ttattgatgc tgcaaaacca ggaatgactg
     8521 gtgtccaatt agatgcagtt gctagagatt atatttcaaa acatggttac ggggaagcat
     8581 ttggacattc tacaggacat gggatcggtt tagagatcca cgaaggacca aacgtttctt
     8641 ctcgtgcaga aaagcaattt gtaccaggaa atgtgatcac tgatgaacca gggatctact
     8701 taccaggaat cggtggagta cgtattgagg atgacttgtt gatcacagaa gatggaaatc
     8761 gtgtgttgac tcgttcacca aaagaattga tcatcttata gtttcatcaa tagaagaagt
     8821 aagcgtaaaa atcagtgttc acagactttg ttatagaaaa tcactcgatt taatgataca
     8881 ctatagaaga acttttaagc tgtaagagat aataaagttg ggtgttttct ccaattcata
     8941 gcagtttgca gctgatcggc ggcagttttc ttaccacgtg atcactatgc cgcatcatag
     9001 agaattcgga tgtatctcgt gcttaggcaa agggaggaat aaataaatgg cagatgaaaa
     9061 aaatttgatt ttaaacgcaa accaagattt aggagagatc gtgatcgctc ctgaagtcat
     9121 cgaagtaatt atcgggattg cagcttctaa agtagaaggc gtatacggaa tgcgcggaac
     9181 ttttgccagc aatgtcactg aattattagg acgtgcagct cacggaaaag gtgtttactt
     9241 agcaaacgag gaagatggct tgaaagtaga tctttactgt tatctagaat atggtgtttc
     9301 agttcctaaa gtagcaatgg aaatgcagga acgggtcagc cagcaagtcc ttttcatgac
     9361 ggatatcgat ttatctgaag tcaatatcca tgtagtagct gttgttcctg aaaaattaga
     9421 acaaccaaca atcgaagaac tttttgaaga cgaagaggaa gagaatgaat aaagaattat
     9481 caagacacga gattcgggaa atggcattgc aggctttatt tccattagac ttcaatgcag
     9541 acctaacaaa agaagatgcg attttcaacg caatcgaatt agaccaccgc gacatgatca
     9601 acgaagatga atcagagttt gttcctgttt atcttgatac gctagttggc ggtgtctgtg
     9661 caaaaaaaga tgaattggat aaagtgattg aaaaacattt aaaaaacaat tggcacatca
     9721 atcggatctc aaaaatggat ttggtgatct tgcgtatcgc gatttttgaa atgacttatg
     9781 tgacagatgt accagcggct gttgctttaa atgaagcaat cgagttggca aaaacattta
     9841 gtgatgaccg ttcacgtaaa ttcgtcaacg gtgttttatc caatgtattg aaagaat
//
LOCUS       DASHWW010000085         9665 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.085, whole genome shotgun sequence.
ACCESSION   DASHWW010000085 DASHWW010000000
VERSION     DASHWW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.085"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..650)
                     /locus_tag="U2R64_002509"
     CDS             complement(<1..650)
                     /locus_tag="U2R64_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8919275.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="U2R64_002510"
     CDS             975..1391
                     /locus_tag="U2R64_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEM8919276.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="U2R64_002511"
     CDS             1388..1858
                     /locus_tag="U2R64_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8919277.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="U2R64_002512"
     CDS             1872..2645
                     /locus_tag="U2R64_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8919278.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="U2R64_002513"
     CDS             2659..3471
                     /locus_tag="U2R64_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8919279.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="U2R64_002514"
     CDS             3525..4490
                     /locus_tag="U2R64_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8919280.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="U2R64_002515"
     CDS             4606..7329
                     /locus_tag="U2R64_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8919281.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANCMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="U2R64_002516"
     CDS             7342..7974
                     /locus_tag="U2R64_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8919282.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9665
                     /locus_tag="U2R64_002517"
     CDS             8873..>9665
                     /locus_tag="U2R64_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919283.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3261 a         1476 c         1884 g         3044 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagacca
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agcgacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaactgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtatt
//
LOCUS       DASHWW010000086         9591 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.086, whole genome shotgun sequence.
ACCESSION   DASHWW010000086 DASHWW010000000
VERSION     DASHWW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.086"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(130..972)
                     /locus_tag="U2R64_002518"
     CDS             complement(130..972)
                     /locus_tag="U2R64_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8919284.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
     gene            complement(1009..2475)
                     /locus_tag="U2R64_002519"
     CDS             complement(1009..2475)
                     /locus_tag="U2R64_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8919285.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            complement(2531..4375)
                     /locus_tag="U2R64_002520"
     CDS             complement(2531..4375)
                     /locus_tag="U2R64_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8919286.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            4977..5927
                     /locus_tag="U2R64_002521"
     CDS             4977..5927
                     /locus_tag="U2R64_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8919287.1"
                     /translation="MKNDIVTYANTKCEEIGISNLEECFFDTNDLSQFLRTGRTNASK
                     LANDLVAKNVLFKINTRPVLFAIKERFEEHFLIPVKDVYESISELKTDLEPNSTDSIL
                     QKMIGYDMSLSDAVEQMKTAVFYPGRGLPMMITGDTGVGKSFFVHTAYQFMKKVNVIH
                     ENAPFKVLNCAQYHNNPELLSGILFGYVKGAFTGADEDRNGLLQDADGGVLFLDEVHR
                     LPPEGQEKLFVYMDGGTYSRVGETIHHASNVRLVFATTEGKEDFLETFMRRIPIHIHI
                     PNIEERGILEKKQIIENTLFSESKNFSKAIDVSPKVTSVA"
     gene            complement(5972..6605)
                     /locus_tag="U2R64_002522"
                     /pseudo
     CDS             complement(5972..6605)
                     /locus_tag="U2R64_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(6865..7413)
                     /locus_tag="U2R64_002523"
     CDS             complement(6865..7413)
                     /locus_tag="U2R64_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919288.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(7414..8271)
                     /locus_tag="U2R64_002524"
     CDS             complement(7414..8271)
                     /locus_tag="U2R64_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8919289.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(8557..8844)
                     /locus_tag="U2R64_002525"
     CDS             complement(8557..8844)
                     /locus_tag="U2R64_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8919290.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(8834..9163)
                     /locus_tag="U2R64_002526"
     CDS             complement(8834..9163)
                     /locus_tag="U2R64_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8919291.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(9240..9386)
                     /locus_tag="U2R64_002527"
                     /pseudo
     CDS             complement(9240..9386)
                     /locus_tag="U2R64_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(9438..>9591)
                     /locus_tag="U2R64_002528"
     CDS             complement(9438..>9591)
                     /locus_tag="U2R64_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8919292.1"
                     /translation="NKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKV
                     LLGIQA"
BASE COUNT         2887 a         1937 c         1473 g         3294 t
ORIGIN      
        1 gattttttat tatcttacgt taatcctttt taaatgtctc ttatagataa caaacagctg
       61 gaaatcacct tgtttttact ataatccatc tctaaagatt ttaaaagcat caatagtatt
      121 actgagcgct cacccattag catgtttcat caaccgattg atgtggacac ctaggtatac
      181 aacttcatcg ttcggaattg ttttatgata aactttttca atgtagtctt tgatcttagc
      241 tgcgctttcc atggcagacg ggtataagat ccacatttga ttgtagaatt cttcctcacc
      301 atcatccaac aaagcatcag aataatatct ttctacaaag aaacgtacat gtgtaatgaa
      361 gcgggcataa tggatcgaat tagtatcgat atctttctgc aacgaatacc ggaccaaatt
      421 gacgatcccg ccgatcattt ttgcatactt gaatccagcg ccgctatcag gatcttccga
      481 ttgtgcattg atcaaatgga aagcaatgtt tgaggcttcc tctttaggaa gatcaattcc
      541 atattgctcg ttcaaaaggg tgagtgcgta cttcccaatt tgaaattctt tgggatagta
      601 gatttttatt tcccagtaca aacggtttgc aatatttacc cctttttgtg cgcgttcaac
      661 tgcaaaatgc aggtggtctg ttaaggttaa atagactcca ggattcagtt ttttatctaa
      721 tcctttttct gcttcaaaaa cgatagtacg agtgatttca aaaaattcaa taggtatttc
      781 ttcaactaac tctaatagtt gtgaagattt cttttcttca aaaggcagaa atattttatc
      841 tactttatct cctgatattt catccccagc tttctgtcca aagcctatcc ctttacctaa
      901 tgcaatcatt tctttgccat tttcttcaac aagtaccaca cttgaattca atactttttt
      961 tattgaaatc actcattatc cccctatcgc tgcttaaaaa gatcgagact actcgaataa
     1021 ggatgcaccg tttgtttcga tcacttcttt gtaccagttg aacgaatcct ttttcaagcg
     1081 gttatatgtc ccatttcctt catcgtctgc atccacataa ataaatccat atcgtttaga
     1141 catttgagaa gttcctgcac taactaaatc aattggtccc cagctagtat aagctatcaa
     1201 atctacacct tcatcgattg cttctttcat ttgttggaag tgtgctttaa agtagtcgat
     1261 gcggtacgga tcatggattt taccatctac tacctgatcg actgctccca taccattttc
     1321 cacaatcatc aacggtactt ggtaacgatc ataaagttcg atcaacgaaa ttttcaaacc
     1381 ttttggatcg atttgccagc cccaatctgt tgaaggcaaa tgaggattct taacccctaa
     1441 aacagtattt cccggtgtgc gttctgcgtt tggatcagct gattctgcca tggacatgta
     1501 atagctgaaa gaaacaaaat ctacggtatg tttctttaaa atttctcgat cttcatcttc
     1561 cattttaatc tgaattcccc gattttccaa atccttttcg attagagcag gatattctcc
     1621 cttaacttga acatctgcat aaaaattatt ttctaagttc tttttcaagg tcagctcaac
     1681 gtcttctggt gcgcaagtta atggataagt catcaatttc gttaacatac aaccaacttg
     1741 gcttcctgga attttttcat gagcatcttt tgtcactaac gcactcgcaa caaattgatg
     1801 atgcaatgct tgatagatat cttgagcttc ttgaccttct gcgcttttct cttggataat
     1861 tccagctgtt gtaaatggat gacggtggat gctgtctatc tcattaaatg tcagccaata
     1921 ttttacgtat ttgccgaagc gatcaaaaca aacgttagcg aagcgaacaa aatcatcaat
     1981 tactcgacgc tccacccagc cattatattt aactgctaaa gctaatggca tttcataatg
     2041 agatagtgtc acaatcggct caattcctaa acgttgcatt tctttaaaga cgttttcata
     2101 aaatgcaacc cctttttcat tcggttccag ctcttctcct gtagggaaca agcgagtcca
     2161 agcaatagag aggcgcaagg ttttaaagcc catttcggca aataaagcta aatcttcttt
     2221 atagtgatga taaaaatcaa cgccccttct ttttgggtac catttatcag atttgtcttc
     2281 actagcttct tttatagact gcagggtgac atgcatatga gcagcaaaat ctttgttgtc
     2341 taaatttggt ttataagtag ccatatccgc tactgaaaga cctttaccgt ctacattcca
     2401 agcaccttct acttgatttg ctgctatcgc gccgccccat aaaaatcctt ttggaaaact
     2461 tgttgtgttt gtcattattc tattctcctc tattccttca ttcaatatat tttttttcac
     2521 tatcttgtgt ttaagctatc ggactgatag ctaagagatc actatcattg gttaccaatt
     2581 tttctaggtt aaatgaacgg atagtgtaat tatccttatt ggttaccaca cagataactg
     2641 tggggtcgaa tcctgcttct ttgattaaat caatatcaaa tgcaatcagc ttttgtcctt
     2701 tggctacttt ttcaccagaa cgaacaaatg cctcaaaccc ttttccttct aactgaacag
     2761 tatcaatacc aatatgaaaa agaagttctg caccattagc cgtttttaaa ccaatagcat
     2821 gcttcgtttc aaataccatt gtgatttctc catcttcagg agctactaat atcccttctt
     2881 caggaatgat tgctactcca tcacctacca taccactaga aaaaacagtg tcttttactt
     2941 ctgatagtga gattactttt ccattcacgg gacttgaaag aacagcatct gaaacaacgg
     3001 ccgtttccat cttagtttca acttcattga caacttcttt atctttataa agaaccaacg
     3061 ctgcagcaaa agcaaccaca aatgaaatcc ccgatactgc aaatgcccaa accagattca
     3121 ttgggtcagc tttgtcagcg aacatcgtga tacttgcaat cccaggaccc actaaagcaa
     3181 aggcttgaag tgcaacgatt cctgcaaatg ctcccccgat caggctagaa aacataacgg
     3241 catataaaac acgtttgtgc agaatcgtta ccccgtaaag agctggttca gtaattccga
     3301 ataatgcaga tatacccgca gaaacagccg tagatttcaa ttttttgtct tttgttttga
     3361 tactgacagc aaagcatgcg ccagcttctg aaatattgtg tgccaatgaa gccgggagat
     3421 aaagaagttc tgcacccaat tcactcatgg atgaaacagc gtaagggatc attgctttat
     3481 gcatacccgt tacaaccatt aatggcagta cagctgctaa gactccggtt gcaacccatc
     3541 caaattgatt gtacaaagac acaatgatag aagagaaagc tgttcctaca ttataaccta
     3601 atggtcctag aagcaacaaa gcaataggaa ctgtaatcaa taagctcatc ataggtacaa
     3661 agaaaatacg aattggtttt ggtgaaactt ttgtaaacca tttttcaagt tgagcataaa
     3721 ataaaacagt taagatggct gggaatactt gagatgcata cgctatatta tccaatccaa
     3781 aagataagaa tgtagcacct tccgccaaca tagctgtcat ttcaggaagg atcaatgcac
     3841 cgacagcaga tactgcaacc aattgattga ctttcaattt attagccgta gtcattgcca
     3901 ccagaatagg caagaaataa agcggtgccc cgccgaccaa atttaaaatc tgataggttt
     3961 gagattggtc actaatcagc cctaagatag aagctagtag caacaaggac ttcaatactc
     4021 ctccacctgc aatcgcagga attaaaggtt ggaaaataga aataataaaa tctaatagaa
     4081 ctgaacctaa tttttgtttt tgttttggtg cttcttcagt atttgaaaca ttgtcaccta
     4141 ataacgcttt cacttcatca tacacttcaa caacatcgtt tccaatgatt acttggcatt
     4201 gcacattttg gcgaacgccc ataacgccat ccactttttc taactggctc atatttacct
     4261 tgctgttgtc ttttaacgta aaacgtaaac gagttgagca atgctccaaa tgggatatgt
     4321 tttcttcccc accgatgtac tgcaatactt cttctgctgt ttgtttgtaa ttcatggtgt
     4381 ttccctcttt tcttttttga gtgatgaact tttgagtcga agtggccatc ctcaacacaa
     4441 aaaacaggca gaaactaaat aaattgacaa caaggcaaac gtgtattgaa acgcatacat
     4501 tgttattcaa cttatttagg tcctgcctgc attaccagtc acatgcctgt ttaagttata
     4561 ttcaatttaa catattagaa tgtaaacgta aataataaaa tgatttttta atcatttttt
     4621 cattttattc gttcaatata gttttcgtgt tctaaaagtt ttgtcttttt tctaagaata
     4681 tcttccaaca tatataactc ttattctctt ctatcttcta gcagatgttc tgtcttttta
     4741 agacctagta taaaaagaat gggttcattt tttctttctt gcaggatgag gttttttata
     4801 taaactttat ttgatataaa gaaaaggcat tcataattgt gctatactac taaaaaatga
     4861 taatacagtg aattagatta gcgctttatt aaattaagag gacagcatat cgatattgct
     4921 tccttttttt tgctatttat ttaagggata gaagtttaga aaggactgtt tataagatga
     4981 aaaatgatat agtgacttat gcaaacacaa aatgtgaaga aattggcatc agtaatttag
     5041 aagagtgctt ttttgacaca aatgacctgt cgcaattttt aagaacggga agaacaaatg
     5101 ccagtaaact tgccaatgac ttagttgcaa agaacgttct atttaaaatc aatactcgtc
     5161 cagtgttatt tgccatcaaa gagcgctttg aagagcactt tttgattccg gtaaaagatg
     5221 tatacgaaag tatatctgaa ttaaaaacag acttggagcc caattctaca gattccattc
     5281 tacaaaagat gattgggtat gatatgagct tatccgatgc ggtggaacaa atgaaaactg
     5341 ctgtcttcta tcctggaaga gggcttccta tgatgatcac tggagatact ggagttggaa
     5401 aaagtttttt tgttcatact gcttatcagt ttatgaaaaa agtgaacgtt attcatgaga
     5461 atgctccttt taaagtactt aattgtgcgc aataccataa taatcctgaa ttattgtcgg
     5521 ggatactatt tggctatgtt aaaggtgctt ttaccggcgc agatgaagat cgaaatggat
     5581 tgttgcaaga tgcagacggt ggagtactgt ttttagacga agtacacaga ttgcctcctg
     5641 aagggcaaga gaaactattt gtttatatgg atggcggaac ttattctaga gtcggtgaaa
     5701 ctatccatca cgcctccaat gtacgtttag tttttgcgac tacagaaggc aaagaggatt
     5761 ttctggaaac ctttatgcga agaatcccta tacatatcca tatcccaaat attgaggaac
     5821 gaggtatttt agaaaaaaaa caaattatcg aaaatactct ctttagcgaa agcaaaaact
     5881 ttagcaaggc tattgatgtt tctcctaaag tcactagtgt tgcataaata tagtcagaat
     5941 attctgaatt attattttct tgaaaaaagt aaaaaaaatc gtatcccaaa ctttcatcta
     6001 catttccaga aagatcttca tgttgataat caattcctga atcaatgacc gctaccttca
     6061 catccttaga acccttggtt tcttcccaag cggatggcat gctaatctct cttaaattag
     6121 cttgtttact ccaattagga tcgttatcga tttcctaaag aatcagttgt atttggctcc
     6181 tcaacatcat tcaacggctc tagttcaacc acatagtttg gctctgcata attgaccata
     6241 tcagaagcat taaatgttct tactgcctct tccacactaa tttcttcgtt caatttcact
     6301 aataatactt gatctcgctt attataatcg ctttcatttg tcctaagagt caaatctttt
     6361 tccaccataa cttttacacc caataaattt tgcggtttat ttttctctgt tgaaattctt
     6421 tgtgtagcct ttaaactgac aattagctca ttgggtacat actctatttg agagtcatct
     6481 aattggctca taatcctttc tttttggtta gtatctgcag ttacttgttt agtatgagcc
     6541 atgaacccaa acatactcac cccaacaacc aatcctaaat atattttctt tttaaacttt
     6601 ttcatctaca tctcctccta atagttttat tttagagtta gctctattac ttatttacta
     6661 actcaacaac agattatcat acacttatta atgaaatcac aatatctcat taaaacacac
     6721 cctaaaatca taaccgttcc tatgctcatt ttttggattt tttaatcacg taaccagaaa
     6781 aataaatccc ctctatttca cgcaaatcaa agaagaacta agtaactacc gtttaaaggt
     6841 agttacttag ttcttctttg attattatct aactttatta ttcattcccc accctttgcg
     6901 cagtgagtct tcggtatctt gttttatctg actggtagtt cttattattt ctccacgatc
     6961 atctaattct ggaacaattg gatatttttc tctgaacaag tctagttctt tcaccacgtc
     7021 attaaacaaa tcttgtttat cttcttgcgt aagattctgt ttaatatact catctaaagc
     7081 ttttctaagc aattcatctc ttgtcatatt agtctcatac ttttctacta aaactctgga
     7141 agtcgcattt aacaaagtcg acagttttaa aggatgcttg gtggaataaa ccttatcaaa
     7201 ctttctgatt ggtgcgccaa ctttttttgt tcttcctcta ctctgtcttt caacattgga
     7261 ggaagttttt atttcttgaa cttggtgcac ttctaattgc ttattttcag atggtgtaat
     7321 tgcttgctgc tttttctttg cttctgcttc tttttttatt ttggcgagtc ctttgttgtt
     7381 cccaaaaata tcaagtcctt tgatgtcagc caattactcc acctccgcat accaattctc
     7441 gtgttcttcc aattctttca aaatactgat aaataattcg tggcttttgc gatcccattg
     7501 ttttaagaga cctttctttg tcttctccat cgtaatacct gatccgtcgt atcgttttaa
     7561 gcgcgcattt ttgagtacaa catttttaat caaatgttcc ccataaatct cttgggcttg
     7621 tttatacatt tcctgatcta ctgcgtcacc gctttccaac atgaaaggaa taacaccagc
     7681 aacatataaa tttgtatcaa attctttcac aaaaaagtcc atatactcaa gatattgcat
     7741 cgcatttctc atcgatttta cttgggtctg taagacgacg attgcccaat ccgcaatgta
     7801 catcgcggat ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa
     7861 ctcatcaaat aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt
     7921 atattggtct ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata
     7981 gaggttattg attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc
     8041 agtcacagta ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa
     8101 gttcatatgc gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat
     8161 caaggttctt tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact
     8221 tttacctacg ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc
     8281 tcttttcttt tagcaatatt catttgatac tattataaca tatttatttt tagttactac
     8341 caaaaaaaag atatatatgt actaccttat aattaataag taaaaggtag tacataaata
     8401 aggaaaagct gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt
     8461 atcgagaagc agagaatact cgccacttta gtcatgtaga cgaatcagat tttcgataaa
     8521 aaagaagccg tccttcttaa gaacgacaac aaatcactag attaattttt tcaactgttc
     8581 ataaaagttt tcatgcgttc cacataacaa tactggaata accttgtttt ctataatctc
     8641 gtaagctact ctatatgttg tgcccgcata tttgaaccca ctagaccaaa tacctgataa
     8701 atccccagtt ttttgttcac ccttatatgg atcaatcgca atttcatcat aaattaaatt
     8761 caaaaatttt tctttcaatg gcttctcttt tagctttttt aaatacttaa tgacatgttt
     8821 tgaaggaacg atttcataag ccaatttctg ttgccaactc ctctttagtc attactttag
     8881 aattagtaag tgtatcttca gcaatatctc taaaggaaga atgcattttg ttttttctat
     8941 tcttaaattc tacaagaatc tcatctttat cgtagccttc tgcaattata tcagacaaaa
     9001 tatcttcgct aaaatcataa aattcttttt gtggttcaac aaattcataa agaataccat
     9061 tctctaccaa ctttgcttca acttcgactc cattaggaac attaaaatct ttaggtactg
     9121 tcaacatgat tgaattgcct tgttttcttg tttttgtaat catttaaatc cctcatttct
     9181 aacagtatgt aattacttag taaatacatt ataccacgag ataatgtatt tacaagtaat
     9241 tactgtgact cgtaatgcgt ccttgctgaa taaatttcaa ccacgtgttc atcttcatct
     9301 accttataaa caacccggtg ttgtctattc aatcttctaa aatacctacc ttcatgtgta
     9361 ggttttaact tctcaaatga ttgggttctg ttgcaaagtt ttaaataaag aataaaatcc
     9421 cttacggtat ctatgattta agcttggatt cccaataata ccttgatttc agtacagacc
     9481 gaaaacccga agagagtgcc ttcttttcgg gttttcttat ataatcctcg aatggcttcc
     9541 atgcctttaa tcgtggtaga ggcagtgcgt aaacttcgat agaatttatt g
//
LOCUS       DASHWW010000087         9328 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.087, whole genome shotgun sequence.
ACCESSION   DASHWW010000087 DASHWW010000000
VERSION     DASHWW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.087"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            317..1102
                     /locus_tag="U2R64_002529"
     CDS             317..1102
                     /locus_tag="U2R64_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8919293.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1115..1966
                     /locus_tag="U2R64_002530"
     CDS             1115..1966
                     /locus_tag="U2R64_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HEM8919294.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2090..2542)
                     /locus_tag="U2R64_002531"
     CDS             complement(2090..2542)
                     /locus_tag="U2R64_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919295.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLMQTDISLVS"
     gene            complement(3007..3375)
                     /locus_tag="U2R64_002532"
     CDS             complement(3007..3375)
                     /locus_tag="U2R64_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HEM8919296.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3525..4007
                     /locus_tag="U2R64_002533"
     CDS             3525..4007
                     /locus_tag="U2R64_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HEM8919297.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSEHMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLLNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4044..5054
                     /locus_tag="U2R64_002534"
     CDS             4044..5054
                     /locus_tag="U2R64_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEM8919298.1"
                     /translation="MISYPLLERNTTIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGINLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5169..5882)
                     /locus_tag="U2R64_002535"
     CDS             complement(5169..5882)
                     /locus_tag="U2R64_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919299.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSSDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPTHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
     gene            complement(6072..6662)
                     /locus_tag="U2R64_002536"
     CDS             complement(6072..6662)
                     /locus_tag="U2R64_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HEM8919300.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7185..7856
                     /locus_tag="U2R64_002537"
     CDS             7185..7856
                     /locus_tag="U2R64_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEM8919301.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLAENYDNHVVIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGY
                     SFILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEM
                     FINAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPNTIYFKRV
                     GGGIT"
     gene            7853..8014
                     /locus_tag="U2R64_002538"
     CDS             7853..8014
                     /locus_tag="U2R64_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919302.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMKYVADEANRK
                     QRKLVGLDK"
     gene            8498..9268
                     /locus_tag="U2R64_002539"
     CDS             8498..9268
                     /locus_tag="U2R64_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEM8919303.1"
                     /translation="MNPTLITKKELLKKLDISTGVLADLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCFKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDIYNQEENQTRHIRNLSDAKLE
                     EEARKVSNYNKKMAAKYVNEEEFCFSKTKIYKRTRGAS"
BASE COUNT         3209 a         1445 c         1763 g         2911 t
ORIGIN      
        1 ggctgtgaca aaagtcttgt cacagccttt ttttccaaat aaatggtttt tcagaagtag
       61 cttcttcgga aataagccga aatttcacaa aaatttgaga agtaattttt gtaaattact
      121 tcttatttct tgaagctggc cacttctgtc acaacctctt tctttataga aataaaagga
      181 cactagcaat tcatgaaaac gattgctaga gcgtatcatt tgctttagac tatatatctt
      241 ggtgtacact cactttaaga cggaaataaa agttatccgt aataacaggt ttaggtatga
      301 aaaaggagtg ggtactatgt ataaggaatt agaaaacaaa gtcgcagtag taactggtgg
      361 ctcaaagggg attggaacag cgattgctca acgattcggg aaagaaaaaa tgaatgtagt
      421 tgtcaactat aactcggata aagaaggagc agaaaaagca gtcaaagcaa tcgaagaggc
      481 aggcggaaaa gcagtctctg tacaagcaga tgtcagttct gaagaaggaa tacagcgttt
      541 acttgatacg gctttagaaa attttgggac actggacgtt tggattaata atgctgggat
      601 ggaaaatcag catccaaccc atgaacttag ccttgaagat tgggaaagag tattaaaagt
      661 caatttgact ggcgttttta tcggaacgaa agcggcttta aattacttta cagagaatga
      721 taaaaaagga aatatcatca atatgtcttc tgttcatgaa caaatcccat ggccaacgtt
      781 tgctcattac gctgcttcaa aaggcggagt aaaactattc accgaaacgg tagcaatgga
      841 gtacgcacca aagggaatca gaatcaatag tataggacct ggtgctatcc gtacacctat
      901 taatgcggca aaatttgatg atcctgaaca aaaagaactc ttggaaagta tgatcccact
      961 aggacgcgta ggtgaaccaa aagaaatagc ggcgacagct gcatggttgg cttcagacga
     1021 atccagttat gttacaggta ttacactatt tgcagatggt gggatgactt tatatccttc
     1081 tttccaaggt ggaaaaggat aagggtgaat aaaaatgggt ttattgattg cattgatccc
     1141 ggcagttggg tgggggatcc agccactgat tttgaaaaag attggtggca gaccaacaaa
     1201 tgagatatta ggaactggta ttggagccgt gctcgttggc ttacttgttc aattattcgc
     1261 ttctccagct ggtatttcag tgactacatt tttgattagt ttactttctg gtgcattctg
     1321 ggtcatcgga caaacaggac agtatacatc tttcaacttg attggtgttt ctaaaacgat
     1381 gccaatttcg actgcattac agttagtcgg aacctcattg attggtgtct tcgcttttgg
     1441 agaatggtct ggaagtatgg gaaaaatcat tggtgcagca gcaatcattc ttcttgtatt
     1501 tggttctgct ttaacggcaa tcagtgatga tcctggaaaa aaaggcggta tcacaaaagg
     1561 aatcagtcta ttagcatcaa caagtattgg ttattgggtt tacagtgcat tgcccaaact
     1621 agttgatgca agcggacttt ccattttctt tccgcaaatg atcggtgtct ttttaggggc
     1681 agtgatttat gtgattttcc gaaaaccaac cgcattttct gaagacaaga gttggaaagc
     1741 aacaatagtt ggagccatct tcagtgtgtc agcattggct tatatttttt cagcaaatga
     1801 aaatggggtt gctactgcat atatcattac acagctaaac gtagttatct ctacattagg
     1861 cggtatgtac atcctgcatg aaaataagac accaaaagaa aaaaaattaa cgattatcgg
     1921 attattgctg atcgtagtag gaagcatggt cacggtcttt atttgaggat aaagatggta
     1981 aaatctcatt tattaaaaaa atatttgttt gaaccaaaca gtaagtactt ataaaaaaat
     2041 agcgctagaa tttccaacat ctctggaatt tctagcgctt tttaattgtt taagatacaa
     2101 gtgaaatatc tgtctgcatc aataattttt cattgatcca ttgactaaag tttacgacat
     2161 aattgaagtt accaccgatt agtatctccg catgattgtc tttataaaga tcgtattgta
     2221 aaagacggtc ttttttattt gcgtaaacat cgttatggta ctggactaat tgttctcgga
     2281 attgattgat tgctgtaaaa tcacgatact gaaggttgaa acgcatcgtg attggtgcat
     2341 ttagcatgaa tcgctgcatt tcttttgctg cttcctctgc ttgatctccg tataggaact
     2401 caaaaagatt acgttcagaa aatttccatt gcccgccaac ctttgttcct tttagttttc
     2461 cttcatgaag ataatttctg atagaacgtg tagtaacacc taattgttcg gctaattcat
     2521 ttactgagta aaaatctttc aatgttcacc ctcctatgtg aatggttcta ctgacttagt
     2581 tgatatttgc ttaatcacga aatgtagaaa gaacgatttt aattaaggtc attgtaaaaa
     2641 tcaagtcaga aaattctaac ttttctttct ctaaagaaat tcgttctctc ctaaagtgat
     2701 attatattta aatatacctg aaaataatgg gcagtattat gaaagatcac tgatattttc
     2761 tcgtattttt tccttattca aaagttttgc aggaaaattg ctgaaaaaat aattttacta
     2821 agtggaaaat tcaaagccat tcaatcagtg atttttttca gcacaagaaa gactccttat
     2881 aaaaatagca gatactttgt caattaagtg tttaaccagg gatgataaaa aggataggat
     2941 tgaacaaaac ctgtataagc tgatgaatag tttcctcgcc agtaaaaggt ttattcgtat
     3001 aaagctttat cgccaaaatt tatcatgacc ttttttatct tcaatattaa atgaaatcaa
     3061 ttgttcaatc aattcccagt tgattacact tttccaagga actttgatga cgttatctgt
     3121 atatacgtag cctgcttctt ggatattttt ttcaagggca cgaatcgctg ctttttccgg
     3181 tgcgatagaa aaatgatttt tagcaaaact aaatgcaata ataaaggtac catggtcagt
     3241 aaacataggt tggttccatt ttacagttgt gtctagctgg ggatacgttt ctgttatctt
     3301 agcaaaaagg tctttgatct tttgttgatg ttctttttct ttgatctgat tgatgatcgg
     3361 ctgaaatttt tccattctaa aacgcctcca ttaagtggtt tgatttattt taccagaaaa
     3421 acaatagtta tgtataaaaa acgaacaaaa cacaagtaat gttgtaaccg ctatatttat
     3481 atgataagat gtctcaaata ataaaataga aaagagacat aaaaatgatt gacttggcaa
     3541 agaaattctt acacgaaaat atatattttg agttgtatca tcatcgagcc atttatacaa
     3601 atgaagatgc tttggtaata aagaaagaac aaggatttac aggtacagag accaaaagct
     3661 tattcttaaa agataaaaaa gataataact acgtatatct gacttttact acgaaacaaa
     3721 cggatttcaa agcattgggg aagatcgtcg gtaaaaggct ttctattgtt tcatcagaac
     3781 acatggaaga acaaacggga caaaagcagg gcgctgtttc tccgtttggt tatgaaaaac
     3841 agattccgat tattattgat gaagagctct tattaaatga aaaacttgtt tttgcaccag
     3901 gtagaccaga tcaaacgatg gtcatccaaa cggttgactt aaacaaaatc atccagctac
     3961 ttgagatgcc gatatttttg atgccggcaa acgaaaaaaa caattaacca agtaaaatag
     4021 tgcatacttg gaggtgaagc aacatgataa gttatccatt attagaaaga aatacaacga
     4081 ttggggttac tgcaccatcc tcaggcgtat cagaggaaca ccattcgtta ctcgaatcag
     4141 ctttaaagag aatggaagaa aaatctttcc aagtagttac tggaaagacg ctttggacgc
     4201 aagataagga aaaatcaggt ccagcaagaa aacgagcaga tgaattcaat caaatgatgc
     4261 aagatgaaaa tatccaaatg atctttccgc cttggggagg agaattattg attgagattc
     4321 tcgattttgt cgattttgat gctctacaac caaaatggat agtaggttat tcagatatta
     4381 gtacgttgct acttgctgtc acattaaaaa cagggatagc cactgcacat ggaatcaacc
     4441 ttattgattt aagaggagag tacttggatg aaacgacagc aatgtgggaa agtgtactga
     4501 aaacaagaga aggagaatcg attctacagc aaccttctga aaagtatcaa aaagagtggc
     4561 cccatgagca ttcatcatct tctgttttcc atctcactga accaacaaat tggcaatcag
     4621 tcagcggaga tgcagtaagg atgaagggac gattattagg tggctgtatt gatacgatca
     4681 gtcatttaat cggtacccct tatggagatg tccaatcttt taaaagaaag tataatgatg
     4741 gaaagccgat cttgtggttt ctagaaaatt gtgagctatc gtcagttgat ttaagaagat
     4801 cacttgttca gatgaaactg gcaggatggt ttgatggcag ctcggggatc atgttcggta
     4861 gaagtgcagc agaggatttg ttagattata aaatgaagga tgtatacgaa gatctgtcaa
     4921 aggaattaaa actaccgatc ttgtatgata ttgattgtgg tcatgtaccg ccacaactga
     4981 cattgatcaa tggtgcctat gcagaagtag cggtagaaga tagaaaagcg actgttttgc
     5041 aaacgtttat ttaaaaaatt ttttcctgcc ttggagttta tcaaagacca acaaatctaa
     5101 atagaaaaga aaatgaaaga agctgacagt attttgccag cttctttttg tatgatctat
     5161 tagaaatttt aattatccat aactatcaca ttgatcagct gtttcacatc atttggatta
     5221 cctgtaggaa tagctactac agatgcatta tcaataattt cttgagttgt ttctctaatg
     5281 aacgctggat aagatgtttg atctgcaggc atttgccaat gtgtaggaac tggataacta
     5341 gtgattgtcc cgtcatggtt acttgaatac actaaaactc cctggtaact gtatttccca
     5401 gtgagcataa ccacatcttt cggatagact gcactccctg catcataagg ggcgataggt
     5461 gttcctgcag gataatgaat aacatgtagt tcgaaatcac tcgatgtatc tctaaaagta
     5521 ttacctctaa tagctagcca aacacgtgcg tactcaattt gtagatcaga atatcctgct
     5581 aacggatcta ttgactgaga agactgtgag gaagttgtgt ctattgttga agaagaaata
     5641 tttgtctcaa ctgtactact agatgtagaa gaagtattgg gctctgagac tttactgctt
     5701 gttgaagatg tattcgtttc agtagaagct gatttctgag tacttgattt ttcagctgaa
     5761 ctggtttgtc tgattgaact tttgtctgtg gtcgcagatg gatcactatt ttctttacta
     5821 ggagacgtac atcctacaag gaataaagag accaacaata aaataaaacc taactttttc
     5881 atataaaata cctcattatt tttttaatac cagtatagcg taatcctgaa tttttgaatc
     5941 cgtaaaacct tgtctatgaa tataaataga gtatatcttc tttgataaat gtcagaaaaa
     6001 gtgtgacaaa taaccatcag taaaattact tgtcatacta ttgagaagga gtatttaatt
     6061 gaagagaatg attaggagaa aggatctccg tactttttat agtaatcata gaatccaagt
     6121 ttgtatagac gaatcgtttt ttctcttatt tcttctgttt caaaatggac tgcttgaaga
     6181 atcaagtctg tgaattctat aggagctgtt ccattcgcag taatcaaatt acgatctttc
     6241 acagcttgtt gttctataaa atcttcttta ttctgataat tttccgattc taaccaagga
     6301 aattgcgcat ttccggtgtg tttgtaacct tgcaataatc cgctctgagc taaataatca
     6361 actgccccac aaatagcagc tactggtacg tctgttttta acaatttatc gattatttga
     6421 tataaatgat gattttttat gtcccatgaa ttgccaccga tcataataaa aaggtcaact
     6481 ttttcaggta tttgttcgat taagtaatcg atttttgttt ttaatcctcc aatggaagtg
     6541 acctctgatt ggatagaagc agttttgttt tgccatccct ctttttggtt tagtgtgcta
     6601 gtaatataag caccttccca atcggcatat tcctctaata gaaacgtaat cgcagttttc
     6661 attttcaagc tctcctttac tatctatgac aaggacaaca gttttaacat acagacattc
     6721 attaaatttg gatagcgaca gcgaaaacaa caattcttaa gttttagaca gagtatacag
     6781 acagtcaact taattaaata cgaactaaat aaaaatgaca ggtaatcatt tttgtttacc
     6841 agcattataa cattttgcat acatggatga caaaagaacc aattcccact tgcttgagta
     6901 caatcttaaa agaaactgga aggcaaaaag taattataga aacgaaaaat aaatcatatc
     6961 gggcactcag acatgaaaac aaccctagaa atatataact agtccaatga aaaaacagcg
     7021 aatgccgtag aaaacaagga ttctgcgtac attcatatct cattttgcga gcatatctgc
     7081 tattactgtg actaaatgtt aatatggtta aaatgaccgt tatatttttt atataaatat
     7141 cgtataatta gtatgaatat agaagaagga aagaaggtgc aatcttggaa cctaaagaca
     7201 agtatttaga ttacgctagg gtcaataaag ataaatttat tgaaacaatc atcaagggaa
     7261 aaatccctga tgatgaaaaa gatgcggtat tcatggctgg aagcccagga gcaggtaaaa
     7321 cagaggttgc actaggttta gctgaaaatt atgacaacca tgttgtgatt gatgcggact
     7381 attttagagc acaatttcca gaatacaatg gaaagaactc aagtgttttt cagaaagctt
     7441 cttcttggtt agttgaacaa tcattaaaat atgtactgga acatggctat tctttcatac
     7501 tagaggatac ttttgctatc cttagtgcag agaaaaatat tattcgagcc cttaaaaata
     7561 actttcgcgt tacgattttc tatgtttacc aagatcccaa agttgcctgg gatttcactc
     7621 gaaaacgtga actagctgaa ggacgtcatg tgccaaaaga aatgtttatc aatgcgtttt
     7681 ttaagtccag agagaatatt gaaaaagtca aaaatagaca tcctgaagta gtccttcaca
     7741 taatgattaa ggattatcaa aacgacattt ctgaagtgca ttatgcagca gataatattc
     7801 aattagtact acccaataca atatacttca aaagagttgg aggaggaatt acatgactga
     7861 gaaagaacaa gtacaacaaa tcgtgaagaa gtataataaa agtatcgctg atttatcaga
     7921 aaacgcctca gcgaaagaat ttaaaacagt aatgaagtac gtagcagatg aagcaaatcg
     7981 taagcagcga aaactagttg ggttggataa ataaattttt taaaccatat ccttgtaaag
     8041 ttgagttttt tgttttaatg aattaagact attaaataga taattattgt aacttaaaaa
     8101 acacagctaa aaattagttg tgttttttat taggtttact tttctggtat aaaaggaact
     8161 agctactttt tcaaaatttc taaatcattc aatatgtagc gcttactaaa ttattcgcca
     8221 taaaatttta taattggatc actcattgtt ttacctaagt catatttaag taataaccgg
     8281 tgtttttaca taagaagact tggggtattt tttagtttga ttagctctga tatacctata
     8341 aagaatatgc taaggtaaga atagtaaaaa ttcacataga tgaggtataa taatgatgtt
     8401 tttatatatt acagataact tgacacaaaa tgagtttttt tcgatttttc aagttatcta
     8461 atgcaattat attgatatca ttaggagctg cattgttatg aatccaacat tgattactaa
     8521 gaaagaatta ctaaaaaaat tagatatttc tactggtgta ttagctgatt taattagaaa
     8581 tggcatgcca aaagagggag aaatgtttaa tcttgataag attattacat ggcgagaaaa
     8641 ttggtctaaa aacatattag gtgagttaga agttggtaga gtatatacta acaaagaaat
     8701 ttcagagaag tttaaatgtt tcaaacaggg tggaatgaga agatctcatc aaactaatac
     8761 tcttgtactg tttagtgatc aaacaggaag taatgtttat aaagataagt ggttaaatgg
     8821 tattttacaa tataccggta tggggctaaa aggggatcaa gtattggata agaatcaaaa
     8881 taaagtttta gccaattcaa aaagtaattt tgtaaagatt catttatttg aaacatttaa
     8941 accaaaagaa cacacgtatc tgggagaagt atatttagca ggacaaatat atactgttaa
     9001 tgaaaaagat agttcgggca acagcagaaa agtatataaa tttccattag ctttaataaa
     9061 tcaagagcaa ttgattgaag ataaagatat atataaccag gaagaaaatc aaactagaca
     9121 tattcgtaat ttatctgatg ctaaattaga ggaagaagca agaaaagtta gtaattataa
     9181 taaaaaaatg gctgcaaaat atgttaacga agaggagttt tgcttctcaa aaacaaaaat
     9241 atataaacgt acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
     9301 ttcaaaacgt cgttgtgctc gacttaat
//
LOCUS       DASHWW010000088         9316 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.088, whole genome shotgun sequence.
ACCESSION   DASHWW010000088 DASHWW010000000
VERSION     DASHWW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.088"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..2122
                     /locus_tag="U2R64_002540"
     CDS             <1..2122
                     /locus_tag="U2R64_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919304.1"
                     /translation="KKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQYK
                     DDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKY
                     GTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFD
                     TIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTL
                     SIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYW
                     ERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENN
                     KEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYI
                     LVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYFSF
                     NTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQIN
                     PYIKEFNLENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIFVS
                     FTINSKKIALKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIF
                     LINLITSIIIYKKNSFKYFKENIL"
     gene            2119..2739
                     /locus_tag="U2R64_002541"
     CDS             2119..2739
                     /locus_tag="U2R64_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919305.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            2853..2990
                     /locus_tag="U2R64_002542"
     CDS             2853..2990
                     /locus_tag="U2R64_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919306.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            3432..3812
                     /locus_tag="U2R64_002543"
     CDS             3432..3812
                     /locus_tag="U2R64_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEM8919307.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            3794..4708
                     /locus_tag="U2R64_002544"
     CDS             3794..4708
                     /locus_tag="U2R64_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEM8919308.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            4948..5637
                     /locus_tag="U2R64_002545"
                     /pseudo
     CDS             4948..5637
                     /locus_tag="U2R64_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5757..5843)
                     /locus_tag="U2R64_002546"
     CDS             complement(5757..5843)
                     /locus_tag="U2R64_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEM8919309.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            6488..7225
                     /locus_tag="U2R64_002547"
     CDS             6488..7225
                     /locus_tag="U2R64_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEM8919310.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            7253..7792
                     /locus_tag="U2R64_002548"
     CDS             7253..7792
                     /locus_tag="U2R64_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEM8919311.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            7808..7978
                     /locus_tag="U2R64_002549"
     CDS             7808..7978
                     /locus_tag="U2R64_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919312.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(8290..8751)
                     /locus_tag="U2R64_002550"
     CDS             complement(8290..8751)
                     /locus_tag="U2R64_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8919313.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     gene            8884..9258
                     /locus_tag="U2R64_002551"
     CDS             8884..9258
                     /locus_tag="U2R64_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEM8919314.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
BASE COUNT         3596 a         1413 c         1455 g         2852 t
ORIGIN      
        1 aaaaaaaata aacgctgttt tatcactttt tgtctgcatt acaatactat ttttttctac
       61 taatgttata aatggtataa agacttctga agcgctatat aaaaataccg ctgaaattca
      121 tatgcaatat aaagatgata tggactttaa cagttatata aacgctttgt atgaaatatc
      181 tacacaagaa aatattaata tttctcaata tagttttact gctgttaacc aactaactat
      241 tcttgctaca aaccctaacg ctaacaaaca ctggaaattt tctaaaaaaa atatattagc
      301 aagaaacgat tctaaagtcc attatactaa taacaaaaat tctaagtacc aattaaaact
      361 tccaaataat tttttaaata taaatattta tcctttttct catgtggaaa atattggatt
      421 aagtgaaata ttatatgtac aaggaaactc aaacaaatta attcctgtac tgaaaaaata
      481 tggaacacct actatttcca atatcaatca atcagatact tttcaaatta atactaatat
      541 tgttcttgtt atctgctatc ttagtatatt tattgtaatt actacaatta tatttgcttt
      601 ttcaaaaatg aaagaaatca ctctaaaaaa aatgttaggc tataactctt ttgatactat
      661 aaaagattct attaaagagt taaacctctt attttgttct ttgattataa ctttcatttt
      721 atctattttt ttgagcatat attacagtaa cgaaaatttt ttcctatcat ttcttctatg
      781 tagtattttt cattttataa ttagtttttt atttatcata gttactctaa gtatctatca
      841 tttatctagt ataaaaaatt atctaaaaaa ttcacgacca cttaagttaa atctttgtat
      901 attaaatatc tgtctattct taagcatgat ccttctgtta atagcttcta caaaagtaat
      961 aaatacccat aatgaagccg aaaataattc tcttaaatat tgggaaagaa ctactaattt
     1021 atacaaaaca aatattacta atcaattaaa tagaaacaac accgtagaag aaaataacta
     1081 cttgaaaaaa gctagtaaat ttgtttataa aatacagaag aattataaaa cttttattat
     1141 cgcgccatac aattacgcaa ctatccaaga gaataataaa gaatttttta ttggacaaaa
     1201 agtttatcca aattttgaag actatgttag tcaacctgct ggtgcaggaa tatgtgttga
     1261 tttaaactat ctaaaatatt acaatcctat ttcttttgaa gaatctactg acttaaattt
     1321 aataaactct gatccactaa ctacttacat tctagtacct aaaaaatata aagaatatgc
     1381 aaaaatgatt gaaaaaaatt atttagaaga catacagttt agacttgagg actctcctcc
     1441 tcaagctcct tataaaaatc ctaatttgaa aaatttaaaa ataaaactaa tatttgttaa
     1501 taataaccaa aagtatttta gttttaatac cttatatgga aaggcaaaag ataactatac
     1561 aataactgat cccatagtta gagttattaa tccagaaata acagaatcat tattttgggg
     1621 aaatatattg actagtgatg gtggattatt ttttgatcag aaacatactt caaaccaaaa
     1681 cttttttaat caaattaatc cgtatataaa agaatttaac ctagaaaata tcataaattt
     1741 ttcttattct gtttttcaag aaactggtga attattatct caaaaaaaag taaataaatt
     1801 aaatgcatat ctacaatatc ttttaatatt aggattattt ataataatta attttcaaat
     1861 gatttttgtt agttttacta taaattcaaa aaaaatagct ttaaaaaaaa tatttggata
     1921 ttcaccaata agtcaagttt tagatttatg tttactccct tttacaatag agttatttgc
     1981 tactatgtgt tttcaattga tattttcaaa aaacacttac ttgtatttta taatttttat
     2041 gatcttttta ataaatctaa ttacttctat tattatttat aaaaaaaata gttttaaata
     2101 ttttaaggag aatattttat gatattatca gttgagaatt tcaccctgtc aattaataaa
     2161 aaaaagatca aacaaaattg gaacttttca atatcagaaa aagattttat tatagtaaca
     2221 ggaaaaagtg gtagtggaaa aactactctg ttaaataatt taagcctaat agataaacaa
     2281 tataccggta acttattcta ttttgaaaag aaagtttcta aacatgatat acaacgtcta
     2341 cgaagaaatc atattagcta tttatttcaa aactatgctc ttcttgaaaa tcaaacagta
     2401 caatacaatt tcgaattagc aaaaaagttt aacagtaata tttccaatga tcatatttat
     2461 aatttattaa cagatttttc tttgccaaaa gatatcttaa aagaaaaaat ctttctctta
     2521 agcggtggag aacaacaaag aatagcatta attagaaata tgttaaaacc atttgatata
     2581 ttatttgcag atgaacctac aggaaattta gataaagaaa actcaacttt tataatgaac
     2641 tttctgaaaa atttaacaga aaaagaaaaa aaagccgttg tactagtaac acatgactta
     2701 aatgttctaa actatggaac taatattata gaattataat ttttacccgt gatgctagct
     2761 gatttaaaac tagcaccacg ggtatttatt ttatattcca tctctcctat cccaaaattt
     2821 aaataatcac ttaataaaaa ggaggcaccc aagtgatttt attgaaaaaa gagtatgaaa
     2881 aattttatga tagacttatt tattctttgc aattgccaaa aaaattaaac cgtcaattac
     2941 aaaagactta tgaaactaaa tcaactgaag aatgggagag ttattgctag atttttggta
     3001 gaagtaacaa aaagtggaca tattatcata atgactcgcc gaaagtctga taaaaaattg
     3061 gctaaaaata ttgctgaatg tttaataaaa ctatcagttt tagctaaata gttagtagtt
     3121 tacacaaaaa agcatttatg ttttttgttg caaagcaaca atttcatctt cggtgaaata
     3181 agcgaaactt tacaaaaagt ggctagcatt tgctagcttt ttttgtattg tggagcgtgg
     3241 cttttgaggg ggattcaagg gggagcttgc gcccctttga caagcggtta tttgcactaa
     3301 atacgtaggt atttggctag caaatataga gcttgccaaa cccttttagt gagctttact
     3361 cattgtacct ttttaggtac aatggtattg cgaacgatac gtccgtagga cgtactgaaa
     3421 gggtgggact tatgagcgaa caaaatcaaa atttggctag caattcttct aaaaaatata
     3481 cctatcgatc cgagccaaaa caaatcagtt ttcgagtgag cgaatccgaa tttgcaaagc
     3541 tgaagcaatc ggctgaagct ttgcaaatga gtgtgccggc tttcgtgaaa gccaaggcac
     3601 aaaacgcgcg tctggtgaca ccgaaagtgg cgccagacat tgcccaggca atcgcgcgcg
     3661 atttagccaa agctggaggg aatatcaatc aaattgctaa gtggtgcaat acacaccaac
     3721 atgacgttgc ttctggtgac gctcaacgtt tatccgaaaa cctaaaaatc atgcaaaagg
     3781 agctacaaaa gatatggcaa caattaaggt aagccgaacc acttcttgta gtcgtgcaat
     3841 taattacgca gaaccacgag caaccattaa aacaggaata aactgtgacg tcgattatgc
     3901 caaaagtgaa atgaaacaaa ttcgcatgct gtatggaaaa gacgaccgtg tacaggcaca
     3961 cttattgatt caatcttttc gaccaggaga aattaccgct gaaaaagcta atcaactagg
     4021 ggcagagtat gcaaaaaaaa tagcccccga tcaccaaata gctatttaca cacatacaga
     4081 caaagaccat attcataatc acattgtcat taactccgtt aatctggaga ctggaaaaaa
     4141 atttcaagct catggtcaag catttctaaa caaatgttat gacctaaatg acgagatttg
     4201 tcttgcacat aacttaccaa tcactgagcg aggaaagaaa ccagaaaaac gaaccatgtc
     4261 tgaaataaaa ttaaaagaaa aaaatgaacc tgtttggaaa gacgaaattc ggattgcgat
     4321 cgatcaaaca atgaaaaaca aaaaaaccag aacctatgac caattttgta attccctcaa
     4381 aacattgggg attcattgct tcaatcgcgg gaaaaatttc acttacgaat tgatccacaa
     4441 aaagaaaaaa gtacgatcca acagactagg aaaggactac gaaaaggaga cgattttaca
     4501 tgagctggac agacgagaac gaacctataa ccaacagcga accaacgagc tacgaagagc
     4561 tcgagctagc attcgcgaaa ctgcagaaga agtacgaaga gaacaacgaa ctcttacgcc
     4621 tgaacaaccg gaaattagac cggctcgaag aaaccatgaa caacacgttg aaagaggaac
     4681 agaccaccaa caagaattat cgctctaaaa cgttaaaaga catagaaaac gaaataaaga
     4741 aacaacgtgc ttttctcgtt ccttatacgc aagaaaggat acaaactacg attgatttac
     4801 aagttaaaaa actccatcaa gagctattag accagcgaaa taaggaacag aaaaaggtgc
     4861 ttattcaacg atcattggat tttcttgccc ccttatgttg cttagtcctg acactgttcg
     4921 cattttggtt agtatgggga ggctaaaatg gcattttatt taccctatct actcattttt
     4981 gttagtattt caggaagtat ttggctcatc tataaaattt tttaaacaag atattcatta
     5041 aaaggctcta aaattcgatt taagcgattt ttctttcttg gctgtatatt ttccttgata
     5101 atcgtttcaa gcggcttatt cggcgtttta gagggaaata agcgcgtttc tagaagtatt
     5161 ttattaggaa atgtcactca aaagtatgaa tcagcgcgtg ataaaaagaa aaaagagcaa
     5221 gcattagcac aaaaaatgga agagtttacc acttgttatg aggaaatgaa cgatattttt
     5281 gtgaatcaag aaaaacgttt gacggataaa aacatggaaa aactcactcg tctttatcaa
     5341 aacttgccag aaaaacagca aaaagaggtt caagacaact atgagcgaac caaaaaagac
     5401 gtgcaatatg taaaagatac aaagatagaa gaagcctgta gtgatctatt tggagacaca
     5461 aacccttggt ttgccagtga agaagaaaaa aaagaaaaac aacaatctgt cacatatgaa
     5521 cgctatgaaa tcttacttca acaagcaact aacatgcaaa atccgacaaa aaaagaaacc
     5581 gccttaaact atctaaaaag tgtcaaggaa tggttagatc agcaacaaca aaattgaatt
     5641 tgatttaaaa tcatgttaaa ctgaatgtgc aaatgatcaa acattagata cacgaaagcc
     5701 ccagagaggt cggattctct ggggcttttt tcaggttgat gtcgccttta ttgattttac
     5761 ttcttgtttc ggttattcaa ccaataactg aataaagaga cacaaactcc tacaagaagg
     5821 gggcaaatga acagttcaaa cattagatac acctccttcc agtcgcaaga ctgtcggata
     5881 ggcgacaagt tattatatct taaaaaatta aatttgtgtg gtgtttttaa gtatcacttg
     5941 ttttagggtt gttagggctt gccctgaccg cctgtaaggc gcttctcgac tagattaagg
     6001 gaaattaatc aagaattgtc ttagaacggc ttagacaagc tttcagagtc tcacacctcc
     6061 tctttgaaca acggttttag caaaggagcc ggaggcgact gcgcagtata atatgagagc
     6121 atagcgatca caccttttta gcgaccgtag ggagcaagtt ttccagttta gaaaaattcg
     6181 cgaacctttt tggaggaaaa agtaggagtt ttttaggcgg gaaattcaat gtgctcttaa
     6241 gatatactgt tagatatact gttagatata ctgttaataa taactgttag ggattagcaa
     6301 ccttatggga gagtaagtat tgacataggt agtgggggat aaattgtcac actatggggg
     6361 ataaattgtc acactatggg ggataaattg tcacactatg ggggataaat tgtcacacta
     6421 tgggggataa attgtgtttt acatcctctt atgtctatga taacataatt tattgaggtg
     6481 atttttattg agtaacgata tagttcgata taataatgga ttaaattctg tccctttaag
     6541 aaaatttacc cctatagata tggatttatt ttggggaata tgttctaaaa tgaaaagaaa
     6601 aggtacaaaa gaagaaattt ttacatttaa acaaataaaa gaattaattg attacaatat
     6661 aaatgcacgt ggcgaccgtt ttgctaatga tttaataaaa atgtcaaaaa aaatcattac
     6721 tttgtctttt atttatgaag acgaaaaaac atatgaacaa ttaaatctgt ttcaaaaatt
     6781 taaaatcgat aaagtgaatg aaacattatt aataaaggtt tctgaagaat ttgaatatat
     6841 acttaattca atcggaacta attttactcg tttcgaatta gaaaatatga caaacttaaa
     6901 gagtagctac gttaaagagt tatatcgcca acttatggct cataaagaca gaagatctaa
     6961 aaaaggtcac tggtttgtaa aaatagaaga ttttagagct ctattagcaa taccagaaag
     7021 ttatcgcatg agagatattg ataaacaaat ttttgcccaa gcgaaaaaag aatttttaaa
     7081 cgttaattca actcaccctg ctatttttaa aacttttgaa atcaaaaaaa ttaaagccta
     7141 caaaggaaat aagataggat ctctgcaaat ttattttgaa gaaaatatac cttcaattac
     7201 cttagataat tggttagaga aataatacct aacaatttag gaggcaatta tcatgcaacc
     7261 caaagaaacc tttacaataa aggaattatc tgaattattt gaaataagta ggcaagcaat
     7321 ctctaaacat gttgataaat tagacccgtc cttattagct aaaaatgagc gtggttataa
     7381 ggttgtatta cgttctggag tattgcaact tgctagcaac ttaggtaacc aaaggttact
     7441 atataggttg catgagtatg aacaagaaaa cgataaaaac gtttatatat caagcaaaaa
     7501 cgtgattgta aacgagttgc tagataagtt gcgtgaagaa aatgaatttt tacgagaaca
     7561 actttccctc aaagagcaaa ataattctaa tatgcaaaaa ttactcgacc agcaacaaca
     7621 gctcacccta caggcaaatc aacagatcga aaaactgcaa gaacagttac aattagctta
     7681 tacggaagaa actccagaag atgaatcaac tactattctt tctgaagaaa cagaatcgat
     7741 agaaaaacac acaaaaaaga agaagcaaaa atggtggcaa ctttggaaat aactggaggg
     7801 aacattcatg acaagaaaaa atcttctatt cggttctatt ttactaggaa ttctaggctt
     7861 cagtccgatg ttattgtcag taatcaataa agggaataaa catggtgaat tgaaattgaa
     7921 tccaaattat tacaacagtc ctaacgaaga attgtttgta aaagagacgg ataaataata
     7981 aaaaagactg ctcttccgag cagccagtta aaaaataatg agtgtttatt cttgaaaaag
     8041 cacgcgctta tgaagcgcta ccaaaaattt accatatttt acaaaaaata acaagtctta
     8101 aaaaaatgac agataaaaat gcacaaagaa ttagatatag ataaccgcga aaaatcaagc
     8161 tttagaaagt tgcttttagc tagaccaatt aaaaatcaca aagtgagcgt ctctatccat
     8221 tggtagaggg gctacttggc atagtgtaca ttatgtcaac tatgcaatta aataactaac
     8281 tacttcatat tagcttaata aaataatcaa aataactagg gggaaaaaca ttgtataaaa
     8341 aaatttttca ttttttaaat aagaatagta aatataaaaa taatttaaga tatctattac
     8401 tattaatcca gatagagcaa accaagtaaa tattccatgt gtaaagctaa aaaaattcat
     8461 ttgaatcaat tcaaataaac ctaatatagt aacaaatata ttaaaaataa tagctgtcaa
     8521 taccagtaaa ttattttttt tattttttga attatcttca tttaaaatag aatttatgtt
     8581 agtactataa aattcacaaa ttttttttag tgtctctata tctggtgttg ttttgttatt
     8641 ttcccacttt gaaatagttt gacgtgtaac gttaaatttt cttgccacat attcttgagt
     8701 ataccctttt ttcactctta attctcttag cttagatcct aaatcctcca ttttttctcc
     8761 tatgtaaacg attatttaca taaaatttta tcataaaaat actaacgcgc caaaaaagtt
     8821 ctttatttta taaaacacac taaaataaaa taattctagt aaaaaagata ggagaaataa
     8881 gttatgaaaa aatttttatg tctttctgct ttaatgggtg tcttattaac tagtggagga
     8941 atagctagtg ccacagaagc tttaaatcta gatgtacccg aagaccatac cgccatttac
     9001 ggaggaggaa tggaagctac agaagaagga ttttcttcta gtaaattgag atatgctgct
     9061 ggcggcgggg atttcaactg tggggttaat ggatttaaag tttatgcaaa ttactaccat
     9121 gctagagcta aacatagtgc aacagctaaa aatggacgag gcggtcaagt acgatcagtt
     9181 cagaaagctg gagtaagagc ttatgcaaca tgcaatgcca cacttactgg aaatactggt
     9241 tggtggaatg tttattaaaa aagagagttt aaactctctt ttttatttac atttgaaagg
     9301 aaattcaaaa tatgtt
//
LOCUS       DASHWW010000089         9209 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.089, whole genome shotgun sequence.
ACCESSION   DASHWW010000089 DASHWW010000000
VERSION     DASHWW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.089"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            470..2107
                     /locus_tag="U2R64_002552"
     CDS             470..2107
                     /locus_tag="U2R64_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919315.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2252..2992)
                     /gene="truA"
                     /locus_tag="U2R64_002553"
     CDS             complement(2252..2992)
                     /gene="truA"
                     /locus_tag="U2R64_002553"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEM8919316.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3183..3818)
                     /locus_tag="U2R64_002554"
     CDS             complement(3183..3818)
                     /locus_tag="U2R64_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HEM8919317.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="U2R64_002555"
     CDS             complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="U2R64_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEM8919318.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5404..6400
                     /locus_tag="U2R64_002556"
                     /pseudo
     CDS             5404..6400
                     /locus_tag="U2R64_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6416..8434
                     /locus_tag="U2R64_002557"
     CDS             6416..8434
                     /locus_tag="U2R64_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEM8919319.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8494..9186)
                     /locus_tag="U2R64_002558"
     CDS             complement(8494..9186)
                     /locus_tag="U2R64_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEM8919320.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2978 a         1706 c         1445 g         3080 t
ORIGIN      
        1 actaatcaga atcgtacaaa tatttaataa ccaaatatat agaacataac ttaatattaa
       61 gttatttgaa attccataaa aaacgactgc aggaattatt gtaagaaaag gataaaaata
      121 gttcagtcca tctccataat tgttaaatgt tgtatagttg attggccctt caaaaataga
      181 agataaccct ttgattcgtg aaagatgaaa agataaatca cctgttgtat aaatttcttg
      241 agcatttctc ataaaattta ctgaatataa agtactaagt aagataagaa ctactaaaag
      301 aaatgctttt ttacttattt tcatagattt gttgttctcc ttttttaatt ctattttcag
      361 tatactagaa ttgtcttttt ttaataagtt ttgcgttaaa tttttcatag cactagtatg
      421 atatactaga aaagaatcaa tttttattac ttttaaatag gagaaaaaaa tgaaaaaaaa
      481 caaaaaccaa ataatagata tcatttttat gttatttcta agttttgctt acgtcatccc
      541 tctattcatg tctatgggaa tctatcatag tgtcaatcag gatacttact ttcatttatc
      601 tcgaatcata ggactagata atgtatggag ttctccagta aacttcaata acttcgatca
      661 tcatggaaca atgatgaata ttttttatcc atggcttact ctttatccag cttttttatt
      721 ttataaaatg atgggaaatc ttgttttaag ttataatatc tactattttt ttatcacttt
      781 tttaacaatg gtcgtttctt atttttctat gaaacaaata aaaaacaatc gttatatttc
      841 gctgttattt tcgattattt atacattttc cgcctatcgt gccattgaca tattccatcg
      901 tgcttcattg ggagaagctg tcgctttaac atttttgcct ttgatactaa tggggtgtta
      961 cgaaatttat attagagatt accaaaaatg gtactggttg tctattggca tgacgctagt
     1021 agtgtatact catttacttt ctgtcgctat ggtttctgta tttattggag gaacgttgtt
     1081 tctttctttt tatttttggg accaaaaaat cgctagactc ttaagtcttt taaaagctac
     1141 cgtcctcacc ttttttttaa gtgcgggatt cttaattcct tttattcaac aatctagagc
     1201 acaagaattg aaagtcccac tgggaaaaga attaagtggt atggctccta gtgatatgct
     1261 gacacacatt ttaaataata actataacaa ctatactatt ggattattct tatttctcgg
     1321 attgattggt gcttttattt ttataaaaaa attaactgct gatgatttat ttattttctt
     1381 tcttggtgta tttgttcttt tttgttcaac caatttattt ccttggcaac tttttaacca
     1441 tacaccagtt aagagtctac aatttgtctg gcggttaaat ggtttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt tagctgtaca cataaacagg ctaaaaagtc
     2161 tttttttata tttctttaat ttgcttcata cattatttaa catcgatatt tatactgtga
     2221 aacatgcgtt tcatccatta tcaaagtatt tttatcgata ataaacttca tccaaaaaca
     2281 gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca aatatttcat
     2341 cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc atgataatcc
     2401 gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt tctccctttc
     2461 gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt ttcaatgcag
     2521 aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc agcttgtcca
     2581 tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa ggaatcacgt
     2641 tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa tggaagcgct
     2701 caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga ttcataaagt
     2761 cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact tgtcctcgcg
     2821 catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca tttgtcatct
     2881 gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca agtctttgcc
     2941 atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc atattttagt
     3001 ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag cacaaaatat
     3061 agctcctttc ttctctaaaa cagaagctat acaagaaaac tgtggaaata tatatttcag
     3121 aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg acggctcaag
     3181 ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt aaagaaaaaa
     3241 ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat agaaggaatt
     3301 cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc aaggtataag
     3361 tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac tggaaacaat
     3421 aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga gacattccac
     3481 gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc tataccatag
     3541 aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac aaatgcagca
     3601 tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca aataagaaac
     3661 gcttttctta caggactgga aacctctcca aatacactga tcacgctctt catttgatct
     3721 aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag cacgcctaat
     3781 aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca ataacaatta
     3841 cctatgcttt taattgttat tataaacgac tttatcttga tttaacagaa acctctattt
     3901 acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac taaatatcta
     3961 acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt tccccacttc
     4021 ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac gaatttaagg
     4081 cagtttccat tgaatcctgg ataacaccga taataaatcc aataccgacg atttgcatcg
     4141 cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac agtgaaccgc
     4201 ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa aggactttca
     4261 aaacaaaagg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc aaggaaatgg
     4321 taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg gaataagact
     4381 cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt gcggcagaac
     4441 ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc aatggatagg
     4501 gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg acaaacagca
     4561 tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagcg attccagtcg
     4621 tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca ataatcactt
     4681 gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc gattctgaac
     4741 gtgctcgaaa agctagtccc aacaatacag cccagaataa gacgccaagg taattcgcat
     4801 caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat aaaacacttt
     4861 ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga acagtaaaaa
     4921 ttgaacttac aataactgct acaagtgcag aaagcaatgt tcccactaaa tataagatca
     4981 aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac gccatcgtca
     5041 agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac gttcccaata
     5101 ttgaaataaa tgtccatgtg gggaaaaaga taccaaacaa tattccgact aaaataccaa
     5161 caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga ccaccctttc
     5221 acaattttaa caatcattgt atcattttat gcaaagaaac taaaggtata attttctaaa
     5281 aattctaaca atacaaacaa ccatttcttg ctaattttgt actttttctg tctacacgtt
     5341 gttttttgag atattctaag ttaggatgtt attaatgggc aacttatcag gaaacgtttt
     5401 cttatgtttt tgtccaattt ttttgtgagg tgtttattct tgaaaaaaat aaagaaggag
     5461 agttatggct tcctgacaat ctttgtcgct tgtataatga tggttttaca gcgtatattg
     5521 atttcagcag tcactattcc tacatatgca acaaaccctg gtcgattcta catctataca
     5581 tttttacaaa cttccgttgt tattggtgca aatttgatcc cactttacat gggttaccaa
     5641 tatcaaaaaa tcgcccgttt aaaagtttta cattatttaa gtcgttttgc ctttatattc
     5701 ctaatagcca cactagtttg caatatcttt tttttacgta caagctggca gcttgaatat
     5761 tcgtgattat tggcttatcc taacacctat cagtcagaat tactttactt atgctgtttc
     5821 ttgtactttg cttttttgta gtattcctta tacagttgga tttttaaata aattatcgaa
     5881 aacaacaatt aaatatctac tattattttt aacaattgga ttagttggct gctctactct
     5941 atttaataaa gacccgtttg cattacagaa tggacagagt attttatgga ttttttattt
     6001 atttttaatg ggttatggtt tgaaagaatg gaactggaaa gaaaaggtcc gctataagct
     6061 tcctcaagta tttatcagct tgattgtttt attcggtttg attattttga tgacacaaat
     6121 ttcactcatc atcagaggaa atacagatac agcgctgagg ttttctaaac catattctct
     6181 cttcgcaatg tattatactt tctcttcgtt tttattttta gaaatgctat ctgataaatt
     6241 aggtataaaa ggaagaggaa attttcttgc tgtatttttg attgtcactc aagttatatg
     6301 taatttccct ttagtttctt atcgcgtatc tacatttatg aaacgtgaat ttccaaactc
     6361 agggaaggca tggctgataa atatcgggca gttttttatt tgctatttat tagcagtgtc
     6421 cctcctagtt atctttttat tttatataca aaaaatccgt ttcattcatc gtttcatcga
     6481 atacttcgct tttgattcga ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg
     6541 gctttttgtt cataaaagtt attttttagt tgcagcattt ttttactgct ttaccttcgt
     6601 gcagattttc gttttagaac caaaagaagg ttggaaagaa actatccagg ttgccttaaa
     6661 aatatttact cagcgacaag cacccatgat cctgacaatc atcattatta tgggattttt
     6721 cttcttacta ttgttgattt ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat
     6781 taacttactg ctcactattt cgacagtaat caaaatggaa atgcgggaag agcctgtctt
     6841 tccttcagat ttaaaaatgc tgaccggatt gtcagaacta ttatcgatgg ttagcccagt
     6901 cttattaatc gtgggcggat tgatccttct cctattattg attactagta ttattgtaca
     6961 acgtagacta caaaaacagt attccttgaa gattcattgg aaacgtcgat ttatcagtat
     7021 cgctgtatta ttaggatgtt tttcgggtgt ctttttcatt aatcacaaaa attcgccttc
     7081 tttcttgctg tttaatttat ttaaagtaaa caagactttc tttaaccagc aaggcgccgt
     7141 aaaagataac ggaccagtca ttcaattcct aaacaatatc gacattaaaa tcatggaaga
     7201 acctgctggc tattcgaaag aaaaaattaa tggaataatg aaaaagtaca acacaaaggc
     7261 agatgaaatc aaccaaacaa gaagtgactg gttaaacaat cagacgatcg ttctcaattt
     7321 aagtgaaagc ttcagtgatc ctgcacgtgt ccctaatctg acagtaccta cagaccctat
     7381 tccttacatc aaaagcatta taacagaagg aacaggagga ttgatgttat ccgtcggtta
     7441 tggtggcgga acagctaaca tggaatggga aggactgaca ggcttgagta tcagtaacct
     7501 gtctgcttcg ttagttacac cttataccca gctagtggag cgtcagaaaa taagtccaaa
     7561 tattaccgat ctattcgatg aaaaaatagc catccatcct tttacagctg ctctttatcg
     7621 cagaaaacaa gtgtttgata aatttggttt tgacaggttc tattatttag acagtccgga
     7681 taaattaact tatacggata aaatagaaca aagcccacgc atatcggatg attcagcata
     7741 caaagaaacc ttgaaagctt tacaaagcaa tacagaaacg tcacaattca tccaattatc
     7801 cactatgcaa aaccatatgc cttatgatga ttactatagt gaattgaact acactgctga
     7861 aggaactgct gtcattccta atagaagaaa agaattacaa acttatatgc aaggccttca
     7921 ctataccgat acagcagtaa aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat
     7981 tacctttgtt ttttatggtg accatttacc cgcaatctat agtgggaatg attcgaaaaa
     8041 atatggatta gaacagcacc agacagatta tttcatttat aacaacaagt atagtcgtga
     8101 acaagcagct acgttaaata aagaagttgt tgctcctaat aactttggtg ctatggctct
     8161 tgagcatgcg aatatcaaag taactcctta ctatgcgttg ttgacagaag tatctaatca
     8221 tctacctgca ttaacaattg atcctacaga aagcttgtct aatcgtttta atggaaaaca
     8281 ggtctttgtt acagaggata gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa
     8341 agaaattcta gaagattatc gtctgataca atatgatctt gttgcaggta accagtacag
     8401 tgcaacatgg gcgacacaaa aaataaaaga ctaacaaata aactgagcaa ggggttgtga
     8461 taaaagacat gtcacaaccc cttgtttatc tcattaattt gcttgtccat aaacgatttg
     8521 attaaagcca tttttcaatt cattattcgc tgtctcgttg aagtaaagat aattatcggg
     8581 attcccctga ttttgttgtg tcaccaatac ttttggctga ttttgctgaa acccgaatag
     8641 atagacgtgc tttttcagat atggttctgt ctctgcatcg gaatagacgg ctgtgatttg
     8701 atagtctgct tgacctgtcc cactttctga ccattctgca gaaacaggca ctccaccaat
     8761 agccatcttc cactccccgt tcaaaatagc ttgagggact ttaagaccat ataagtccac
     8821 actcatttga ttcgtataac ttttgtattg ttgtcccatt gtttggcccc atttggtcat
     8881 aaatgcctct aattgtgcgg atttgtctgc attccacagt gtttgttcaa cttgttcgct
     8941 gctttctgaa gaggaagatg aagcctctac agaagaactt gaagtagatg tttgagttgt
     9001 ttcagtcgtt ttggaagact ctgacgaagt agaggtatct gctgtttctg tacttgctgc
     9061 agttgacttg ctctctgtgc tagttgttgt agtagttgca actgttgctt tcgctgtttc
     9121 ttttgttgat tcttttttcg attcattccc gttggtacaa ccagctaaca aaaaagctag
     9181 accaattgtt actaaaatcc tttttttca
//
LOCUS       DASHWW010000090         8969 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.090, whole genome shotgun sequence.
ACCESSION   DASHWW010000090 DASHWW010000000
VERSION     DASHWW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.090"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(57..350)
                     /locus_tag="U2R64_002559"
     CDS             complement(57..350)
                     /locus_tag="U2R64_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HEM8919321.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="U2R64_002560"
     CDS             complement(378..1043)
                     /locus_tag="U2R64_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEM8919322.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="U2R64_002561"
     CDS             complement(1183..1815)
                     /locus_tag="U2R64_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8919323.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /locus_tag="U2R64_002562"
     CDS             complement(1822..2889)
                     /locus_tag="U2R64_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8919324.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2886..3617)
                     /locus_tag="U2R64_002563"
     CDS             complement(2886..3617)
                     /locus_tag="U2R64_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEM8919325.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="U2R64_002564"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="U2R64_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEM8919326.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="U2R64_002565"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="U2R64_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEM8919327.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5780..6949
                     /locus_tag="U2R64_002566"
     CDS             5780..6949
                     /locus_tag="U2R64_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEM8919328.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7216..8850)
                     /locus_tag="U2R64_002567"
     CDS             complement(7216..8850)
                     /locus_tag="U2R64_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919329.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2856 a         1701 c         1333 g         3079 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
      661 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
      721 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
      781 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
      901 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
      961 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
     1021 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
     1261 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
     1321 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
     1381 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
     1441 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
     1501 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
     1561 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
     1621 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
     1681 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
     1741 ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt catctactaa
     1801 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
     1861 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
     1981 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
     2041 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
     2161 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
     2221 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
     2401 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
     2461 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
     2521 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
     2581 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
     2641 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
     2701 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
     2761 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
     2881 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
     2941 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
     3001 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
     3061 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
     3181 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
     3241 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
     3301 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
     3361 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
     3481 ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
     3721 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
     3841 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
     3901 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
     3961 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
     4021 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
     4141 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
     4381 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
     4441 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
     4561 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
     4621 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
     4681 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
     4801 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
     4861 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
     4921 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
     4981 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
     5041 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
     5161 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
     5221 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
     5281 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
     5341 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
     5401 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
     5461 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
     5641 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
     5701 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
     5761 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
     5821 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
     5881 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
     5941 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
     6001 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
     6061 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
     6121 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
     6181 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
     6241 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
     6301 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
     6361 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
     6421 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
     6481 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
     6541 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
     6601 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
     6661 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
     6721 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
     6781 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
     6841 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
     6901 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
     6961 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
     7021 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
     7081 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
     7141 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
     7201 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
     7261 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
     7321 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
     7381 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
     7441 tacaggtaaa actattgttt tgccttttga agatttaagc gtaaatgtaa tttcatcttt
     7501 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
     7561 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
     7621 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
     7681 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
     7741 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
     7801 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
     7861 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
     7921 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
     7981 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
     8041 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
     8101 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
     8161 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
     8221 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
     8281 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
     8341 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
     8401 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
     8461 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
     8521 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
     8581 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
     8641 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
     8701 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
     8761 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
     8821 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
     8881 tttttttaaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
     8941 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DASHWW010000091         8708 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.091, whole genome shotgun sequence.
ACCESSION   DASHWW010000091 DASHWW010000000
VERSION     DASHWW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.091"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            7..2199
                     /locus_tag="U2R64_002568"
     CDS             7..2199
                     /locus_tag="U2R64_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HEM8919330.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            2216..2692
                     /gene="ybeY"
                     /locus_tag="U2R64_002569"
     CDS             2216..2692
                     /gene="ybeY"
                     /locus_tag="U2R64_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEM8919331.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            2676..3071
                     /locus_tag="U2R64_002570"
     CDS             2676..3071
                     /locus_tag="U2R64_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HEM8919332.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            3086..3985
                     /gene="era"
                     /locus_tag="U2R64_002571"
     CDS             3086..3985
                     /gene="era"
                     /locus_tag="U2R64_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEM8919333.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            4128..4940
                     /gene="recO"
                     /locus_tag="U2R64_002572"
     CDS             4128..4940
                     /gene="recO"
                     /locus_tag="U2R64_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEM8919334.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            5324..6241
                     /gene="glyQ"
                     /locus_tag="U2R64_002573"
     CDS             5324..6241
                     /gene="glyQ"
                     /locus_tag="U2R64_002573"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEM8919335.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            6243..8318
                     /locus_tag="U2R64_002574"
     CDS             6243..8318
                     /locus_tag="U2R64_002574"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEM8919336.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT         2936 a         1559 c         1849 g         2364 t
ORIGIN      
        1 aagcacatgt tgaataaaac actgcagaaa ctacaagaaa aacttggaaa ggcagcattg
       61 cctttcctgc tgttcttgtt ttttatcatt atctgcggcg ttacatttag tagtgtcaaa
      121 caaaaggcca atgatttcag agaaggccaa gtagcagaag aaagtatccg tgcgaacaaa
      181 acgatcgaga acacggaaga aaccgaacaa aaaagaaaac tggcagcaga agcagtcact
      241 ccagaataca cttaccaaaa agatcttgca gatgaccaga acaatcggat caagcaacta
      301 tttgaattga tcgataaaac gaatgatgcc atcaacaaat cttatgacga aaagattgat
      361 aaggcaaagg aagatgaaaa tatcccaaag cctactacag aagagcggat cgccgcgttg
      421 aagaaaaatt ttgaaaatgt gaatgcagaa aatgttgcgt tttatcaaaa actaccgaac
      481 aatttttatt cgacgatatt tgaaatgact gaaactgaga tccatactgt gagggatgag
      541 agtctgaagc tcattgacga acagatgagc aaacaagttc gtgaaagtga attggaagct
      601 tttaaacaag aagcagaaga gcaaatccaa tatttgaatg tcacaccagc acaacaacaa
      661 atgattcgct acttagtgga tcaaggtatc gtagtgaatg acgtattgaa tgagaaaaag
      721 acagaagaat tgaaacaatc cgcacgagaa gctgtacaac cagtgatgat cttccaagga
      781 gaaatcattg ttcgtgaagg taatcaaatc gatgcttcag ctatgaaaaa attggaatta
      841 ctaggactga ctaatcaaac aacttcgatt tttccgctaa ttgccatggt tttagctgtt
      901 ttgcttcaaa tcggcgtact gatttataat tcacttcaat tccaaaatgc aggagaaaga
      961 acaaaatacg tgcttttcta tgtgacagct atgtcagtca gcatagtgct gatgaaattt
     1021 ttccaattat tccaaacgga acaagctact tatatcccgc tgttttatcc cgctgctttt
     1081 gcaccacttg ttttaagctt tttcttgaac cgaagagcag ggatcatggc tggtattttc
     1141 caagcagtat ctgcactttt cattttttat gattcgattg gcacgaactt tctaacgatt
     1201 atcttgatgt cttatgtttt ctctgggctc atggcaacga ttgtcagacg caaacggatc
     1261 tcagaacaag gattatctgc tgccatgtgg gtcattattt ttcctgtgat gatggatgtc
     1321 attttgatcg tctatcaagg aatgagcttt ggtgatgcaa cgacttggtt aatgcttgtc
     1381 tgcgggttca ctggtgcact cttctcattc ttgctgacga tcggtctaca cccatatatt
     1441 gaattgatgg tcaatgatga cagtgtaatt gtattaaatg aactcagcaa tccaaatcat
     1501 cctttattga aacagttgct ggaagaagcg ccaggtactt atcatcatag tatgatggta
     1561 gctaatctaa gtgctaacgc tgtagcagaa atcggcggac gttctttgct aactcgagta
     1621 gcttgctatt atcatgatat cggcaagatc aaacatgcta gctttttcgt tgagaacttg
     1681 ccttcaggag cggaaaaccc gcacaatttc ttattgccag aagacagtaa acatattatc
     1741 tttggacatg tgacagatgg agccaaaata ttggaagatt ataatatgcc gcaaatggtg
     1801 atcgatattt gcaaacagca tcatggaacc acgctaatgc gttatttcta catcaaagcg
     1861 aaagaacgca atccggaagt aacagaagag caattccgtt atcctggacc aaaaccgcaa
     1921 agtcgtgaag cagggatcgt caatattgct gacagttgtg aggctgcagt acgggcaatg
     1981 gatcatccga cgagcgaaaa aatcgaaagt tttgtccata atcttatcga agagcgtatt
     2041 tccgatggtc aattagacga tagtggactg accttgaaag aaatccgaaa agtggaaaaa
     2101 tcattgatca gcggtttaag tagcaccttc cattctcgga tcaaatatcc taaaatgaaa
     2161 acagaagttg agaagataaa ggaagaacaa gaagaataga aagaagcgat gtataatgga
     2221 tattaccttt atggatgaaa caaaccaagt ctcagaagag aaaatgaaag aaatcgatga
     2281 cttgctgcaa tttgcagcat cttatttaaa gctgccagag gaaacagaaa tgtctgttac
     2341 tttcatggac aatgcggcaa tccaagtaat caatcgtgat taccgtggaa aagatgcacc
     2401 gacagacgtc atcagttttg ctctggaaga agaaggcgaa gacgaaatcc cagtgatttt
     2461 tgaagatgga gagaatccat tgcctcgtgt actaggagac atcatgattt ctattgaacg
     2521 tgctgctgaa caagcagaag cttacggcca ttcatatgat cgggaacttg gctttttagc
     2581 ggtacatgga ttcttgcata tcaacgggta tgaccatatg acaccagaag atgagaaaga
     2641 aatgtttggt ttacagaaag agatcttgga tgcctatgga ctcaaaagat aaaaacgtag
     2701 agaaaaacaa acatttcctg atgtctgtgg aatttgctgt ccaaggagtc aaaaccgttt
     2761 ttgaggaaga acgcaatatg aggaaacatg ttgcgttcgg tatccttgct ttatttatgg
     2821 gcgtgatttt ccagcttgat cggatagagt ggttatggct gcttttagct gtttttctcg
     2881 tttggatagt agagatcatc aatactgttt ttgaaaatgt agtggacatg tttacggatt
     2941 ttcattttca tccgattggg aaaaaaatca aagatatggc agctggagca gttttagtga
     3001 ccgcttgttt tgctgtcatc attgggttga ttttatttgt ccctaaaata tatcatttgt
     3061 tgtttaatta aaaaggagaa cgtatatgcc agaacataaa tcagggtttg tcgcaatcgt
     3121 cggccgcccg aatgtaggaa aatccacatt attgaaccga atcgtgggtc aaaaaattgc
     3181 cattatgagt gacaaggcac agacaactag aaataaaatc caaggagtat atactacacc
     3241 agaagctcag ctgattttta tcgatacacc aggaatccat aaaccaaagc atcgtctagg
     3301 agattttatg gtagaagcag cttacagtgc gttgaaagaa gtggatgcag tcttatttat
     3361 gatcagtgct gatcaaaaac gcggccgggg agacgatttt attattgaac gtctaaaaaa
     3421 cgtgcattct ccagtttatc tgattatcaa taaaatcgat aagatccatc cagacgagtt
     3481 gctgggaatc atcgaagatt attcgacgca gatgcctttt gcacaagtga ttccgatctc
     3541 tgctacagaa ggaaacaatg tcgaacgctt aatggatgta ttagtcagtg aaatgccaga
     3601 gggcccacaa tattttccag atgatcaagt gactgatcat cctgaatact ttatcgtttc
     3661 tgaattgatc cgtgagaaag tcttgttttt aacacgagac gaagtgcctc attctgtcgc
     3721 agtcgttgtt gattcgatga agcgaaacga gaatgataaa atccatatcc aggccacgat
     3781 catcgtcgaa agagatagcc aaaaaggaat cattatcggc aaaggcggaa aaatgctgaa
     3841 gcaagtagga acgaaagcaa gaaaggatat cgaaaatctt ttaggagaca aagtatttct
     3901 agaactttgg gtcaaagtcc aaaaagactg gcgagacaaa aaagtctatc tgcaagactt
     3961 tggctaccga aaagacgaat actgatattc tgaacttctt ataggttaag tatagaaata
     4021 aactggataa aaatccgcac gttgagaaaa acggcggaag atcgaaacat aaataatctg
     4081 gatcggcaga atctgctttt ccagatttat tttttaggag ggagaatatg agccagcttg
     4141 cagaatcgaa aggcttgatt ttatctagcc gtaattacaa agaaaaagat aaattagtca
     4201 aaatctttac ggaatcttct ggcaaaatga tgttttatat caaaggaatc catcggcaaa
     4261 atcagccatt agctccggct ttgctcccct ttaccgaagc agtctatatc ggtaattttc
     4321 gaagtgaagg tttgtcgttt ttaagcagtg tcaaagacgt ccatgcgttt cggaacatcc
     4381 aagaagatat ctttttgagc ggttatggta cctatttgct aaatctagta gatgcagcaa
     4441 tcgaagatca tcaatatgac ccgcatttat tccaatttac gcaacaagct ctgcagcgga
     4501 tggatcaagg agatgatgca gaaatcatca cgaatatctt tgaagttcaa atactgcaac
     4561 gcttcggaat cgcgccaatt tggacgcact gtgtcgtatg cggggaaaca aaaggaaaat
     4621 ttgactattc ttccaaatct ggcggtgtga tatgcgagaa acactggcca atggacgaac
     4681 accgttatca tgcagatcct cgcgctgttt atttcgttcg aatgttttcg gctatttctt
     4741 atgataagat cagtggaatc cacttgaaag aagaaacgaa gcaggcaatc cgtgacctca
     4801 ttgaccagtt gtatgatgaa tatgtcggta ttcatctaaa aagcaaaaag ttcattgatc
     4861 aaatgaagtc ttgggcacac gtattaaaga cgccagagaa aaatatgcct gaaaaagaga
     4921 tacctgaaaa agaagaataa atgaaagata caacaaaaaa atcaaaacta tttgacaaat
     4981 acagggactt ccgtctatta ttaaccgtag attaaataga tcgttcactg agaggatcta
     5041 ttatataaac aagaaaactg caaaatgaat acgtacattg accaagatca gtaaaaaaca
     5101 cgtggtttag cgagttcggg agagtggaag ccggacccaa acgatttttg aagaggcact
     5161 tgcgagtacg ataaatgaag ctgccgaatc tttattcgga agtagggtgg aaccgcgaaa
     5221 ttattcgtcc ctatgtctgt aatcagacat agggactttt tgtcgttttc tttcctgtat
     5281 tcttattgac agcaacgctt aaaaattgaa aggggcaaaa cagatgagta aaaaattgac
     5341 cgtccaagat atgattttaa cattacaaaa attttggtca tcaaacggct gcatgctgat
     5401 gcaagcttat gacacagaaa aaggagcagg tacgatgagc ccatatacat tcttacgggc
     5461 aatcggaccg gaaccatgga atgctgctta tgtagagcca tcccgccgac cagctgacgg
     5521 gcgttatgga gaaaacccaa accgtttgta tcagcatcat caatttcaag tcgtaatgaa
     5581 accttcacct gaaaatatcc aagagcttta tttagaaagc ttgcgtcttt taggaattga
     5641 tccattagaa cacgatattc gttttgttga agacaactgg gagaacccat cgatggggtg
     5701 tgccggtgtg ggttgggaag tatggcttga tgggatggag atcacacaat tcacgtactt
     5761 ccagcaagtc ggaggactac cttgtaaacc agttacttct gagatcactt atggactaga
     5821 acgtcttgct tcatatattc aagaagttga aagtgtctat gatctggaat gggctgatgg
     5881 tgtgaaatat ggcgagatct tcaaacaacc agaatatgaa cattccaaat attcttttga
     5941 agtaagtgac caagacttgc tactaagcaa ctttgaccgt tttgaaaaag aagctaaacg
     6001 ctgtatcgat gaaaatcttg ttcatccagc gtatgattat attttgaaat gcagccatac
     6061 attcaattta ttagatgctc gcggtgcagt atccgtaaca gaacgagcag gttatctttc
     6121 ccgtatccgc aacatggctc gtgctgtagc caaaatcttt gtggcagaac gcgaaaaatt
     6181 aggattccct ttattgaata aaaacacagc aaatccagaa aacatgaagg aggctgaata
     6241 agatggcaaa agacttatta cttgaaatcg ggctggaaga aatgcctgct catgttgtca
     6301 caccaagcat gaaacaatta gaagaaaaaa cagcaaaatt tttagatgaa aaccaattga
     6361 cttatgatac gatcgaaacg ttttctacac cgcgccgctt agcaatcaaa gtaacaaaca
     6421 ttccagaacg tcaagcagac agtgaagaag aagtcaaagg accagccaaa aaaattgctt
     6481 tggacgcaga tggaaactgg acgaaagcag ctgaaggatt tgtccgcgga caaggtctga
     6541 cgacagatgc tatcactttt agagaattaa aaggcgtgga atatgtctat gtaacgaaat
     6601 acactcacgg caaagaagcg aaagaagtat tgacaggttt agcagatgtc attaaaagcc
     6661 tcactttccc agtaacgatg cattgggcag aatacgattt tgaatatatc cgccctattc
     6721 actggatcgt ggcattgtta gatgacgaag taatcccgtt tgagatctta gatgtcaaaa
     6781 caggcagagc ctctcgagga catcgtttct taggcgaaga tgtgacattt gcgcatgcaa
     6841 aagaatatga agaaaaattg aatgaacaat tcgttattgc ttcaccgcaa aaaagacaag
     6901 aaatgatcgt tacacaagca aatgaattag ccgaaaaaaa tcactgggtt attgatctag
     6961 acgaagattt actagaagaa gtcaacaatt tagtcgaata tccaactgtc ttttctggcg
     7021 acttcgaaga aaaatatctt tctgttcctg aagaagtact agtcacttct atgaaagaac
     7081 atcaacgtta tttcgaggta cggaacgatc aaggtatgct gcttcctcat tttatttctg
     7141 ctcgtaatgg tgatcgggta aaattggaaa atgtggttcg aggcaatcaa aaagtattga
     7201 cggctcgttt agaagatgcg gaattctttt ataatgaaga caagaaagct tcaatcgacc
     7261 aatacgttga aaaactaaaa actgttactt tccatgaaaa aatcggtagt atctatgaga
     7321 aaatgcagcg ggtacaagtc attgcccgta tcattggcga acaagtagga ctatctgagg
     7381 aagaattgat ggatctgcaa cgagctgctg aaatctataa atttgatcta gtaaccaaca
     7441 tggtagggga atttcctgaa ctacaaggga tcatgggcga aaaatatgct ctgctgaaag
     7501 gcgagaaacc tgctgtagca acagcgattc gtgagcatta catgcctata tccagtgaag
     7561 gagagctacc tcagtctaca gtaggttctg ttttagcgat tgcagataaa ttagatagca
     7621 ttttttcttt ctttgcagtt gggatgattc caagcgggtc aaacgatcct tatgccttac
     7681 gtcgccaagc atacggtgtc gttcggatca tcgaatcgaa aaaatgggcc tttcctttgt
     7741 ctgttctgca agaaacgatt agtgatgtta tcagtaaaga tacggatcgt ttcggcattg
     7801 gtttatcaga agggcaacaa caggtgatcg actttatcaa aggccgtctg cgccaattat
     7861 tgacaacgaa gaatattcgt catgatgtca tcgaagctgt tttgaatgca gaacaaaaag
     7921 atctgacaaa agtatttgca gcagcacaat tgttcaagca gcatcttgca gatgaagact
     7981 tcaaaccatc gatggaagct ttgacacgtg tcgtgaactt agcgaaaaaa gcggagcttg
     8041 aaaaacaatc agaagtagac cctgaactgt tcgaaaatga agcggagaaa gaactgcaca
     8101 aagcagtaga ggcaatgaaa aaaagctttg ctgaccaaac gatcaacgaa aattatgatc
     8161 agcttgtaag ccttcgccca ctgatcgaaa attattttga tcagacgatg gtcatggcag
     8221 aagaaccagc agtacgtaag aaccgattaa cgcaattaag tcaaattgct gccatggctt
     8281 tgtcgctagc aagtttagat caaatcatca caaaataatt tctaatatgt aaataaacca
     8341 gagaataggc acaaaatagg ctatttctct ggtttatttg ttataaatat aaataactat
     8401 acccgtggtg ctagttaatt ttttcctagg tattatacaa gtaatttgag tcggtcaatt
     8461 tcaactgaat tatctaaact aactgatcta cttttagata attcagttga aatttattgg
     8521 taaactgtcg cttttctttt taaatggcaa aaatttttaa taatatatga caatttagaa
     8581 atcaactata agactgatta attcaaaatg atcttagaat cattgtatga acactaaata
     8641 ctatattgtt ttctattaat cgttatataa acgattatga attcaaagct actttttatg
     8701 acgtcaat
//
LOCUS       DASHWW010000092         8624 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.092, whole genome shotgun sequence.
ACCESSION   DASHWW010000092 DASHWW010000000
VERSION     DASHWW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.092"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(141..416)
                     /locus_tag="U2R64_002575"
     CDS             complement(141..416)
                     /locus_tag="U2R64_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEM8919337.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(659..1969)
                     /gene="der"
                     /locus_tag="U2R64_002576"
     CDS             complement(659..1969)
                     /gene="der"
                     /locus_tag="U2R64_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEM8919338.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="U2R64_002577"
     CDS             complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="U2R64_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEM8919339.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3515..4195)
                     /locus_tag="U2R64_002578"
     CDS             complement(3515..4195)
                     /locus_tag="U2R64_002578"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEM8919340.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4244..4879)
                     /locus_tag="U2R64_002579"
     CDS             complement(4244..4879)
                     /locus_tag="U2R64_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8919341.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4945..6348)
                     /locus_tag="U2R64_002580"
     CDS             complement(4945..6348)
                     /locus_tag="U2R64_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HEM8919342.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6335..7366)
                     /locus_tag="U2R64_002581"
     CDS             complement(6335..7366)
                     /locus_tag="U2R64_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919343.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7397..7618
                     /locus_tag="U2R64_002582"
     CDS             7397..7618
                     /locus_tag="U2R64_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEM8919344.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7783..8520)
                     /locus_tag="U2R64_002583"
     CDS             complement(7783..8520)
                     /locus_tag="U2R64_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEM8919345.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
BASE COUNT         2393 a         1858 c         1461 g         2912 t
ORIGIN      
        1 aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg aatctctgtc
       61 tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc cctagagcca
      121 caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc tggtttgaat
      181 gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt acgacctttg
      241 cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg
      301 ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt tgcatctttt
      361 ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt tgccatggat
      421 agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa ctttctgagt
      481 ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc acgatatcat
      541 atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta gtcatagaaa
      601 cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct
      661 attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat gcttttctga
      721 tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa
      781 cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc aggcgttttc
      841 ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca ttcaacacag
      901 ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca ggcagacgtt
      961 ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca agataccgga
     1021 attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc tttacaagat
     1081 cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa cccgctactc
     1141 gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg atatcagaac
     1201 ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg tatacttttc
     1261 cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt tcagaaacga
     1321 agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt acacgttctt
     1381 ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca atcaaactaa
     1441 acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc actgcttcat
     1501 ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga tcgcctagcc
     1561 ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact ttattgactg
     1621 ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca tctgcgtctg
     1681 tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca atcgcgattt
     1741 ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt
     1801 cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga tcacgagtta
     1861 ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta aaaatcgtag
     1921 acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata ttatttcctc
     1981 ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc aagcatagat
     2041 tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt tcaaaagaaa
     2101 aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa ttatttttca
     2161 gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa aatgtctccc
     2221 atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt tggttcttct
     2281 tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg ttcttctgga
     2341 tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc atgtggtgtc
     2401 gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc agggaacact
     2461 tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact
     2521 ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa
     2581 acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc attgacagcc
     2641 aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg gactagaccg
     2701 tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg
     2761 agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc tctttcgttt
     2821 tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat ttcgatgatt
     2881 ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg atcttccacc
     2941 attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca
     3001 tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat atcttcccaa
     3061 acttttttag catctaaacg gcgttttgaa agtaggtagc tgccgttttc tttatctttg
     3121 ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac ttcgctgata
     3181 tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac tccagcccct
     3241 tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt aacaacatcg
     3301 ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt gttctcttga
     3361 ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc gtaagtacgg
     3421 tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt cgttttcctt
     3481 gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa ccttttttca
     3541 aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc gtatcgatac
     3601 gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca taatggtctc
     3661 tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt tcttggttct
     3721 ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt ttcacttctg
     3781 cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc
     3841 ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca gagacttcag
     3901 aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt gatgctatga
     3961 atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg atcagcgaaa
     4021 ctagcccttc ttcatctgaa aaagatacat tgttcgtaat agctaaataa gttactgcgc
     4081 gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat atcttggcaa
     4141 cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt gtcatgatat
     4201 aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta attcttaatt
     4261 cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca aacaattgat
     4321 cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct tgaacagtcg
     4381 ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat
     4441 cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct gcaatactgc
     4501 tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt gtactagatt
     4561 ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt tctactactg
     4621 atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca tttctgatcc
     4681 agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa aatagcgaaa
     4741 gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa acttcatcat
     4801 ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct gtagattgat
     4861 gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat tataccatag
     4921 gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata aatttagtaa
     4981 aatcgtttcc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
     5041 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
     5101 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
     5161 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
     5221 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctt
     5281 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
     5341 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
     5401 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
     5461 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
     5521 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
     5581 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
     5641 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
     5701 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
     5761 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
     5821 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
     5881 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
     5941 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     6001 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     6061 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     6121 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     6181 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     6241 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     6301 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     6361 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     6421 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     6481 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     6541 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     6601 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     6661 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     6721 aaaggtggat acatctgctt tgttgcagat aaacctctga ctcatcattg ttttttgcca
     6781 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     6841 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     6901 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     6961 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     7021 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     7081 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     7141 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     7201 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     7261 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     7321 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     7381 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     7441 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     7501 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     7561 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     7621 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     7681 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     7741 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     7801 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     7861 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     7921 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     7981 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     8041 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     8101 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     8161 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     8221 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     8281 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     8341 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     8401 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     8461 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     8521 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     8581 aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaa
//
LOCUS       DASHWW010000093         8493 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.093, whole genome shotgun sequence.
ACCESSION   DASHWW010000093 DASHWW010000000
VERSION     DASHWW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.093"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..173)
                     /locus_tag="U2R64_002584"
     CDS             complement(<1..173)
                     /locus_tag="U2R64_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8919346.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="U2R64_002585"
     CDS             complement(593..1714)
                     /locus_tag="U2R64_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HEM8919347.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="U2R64_002586"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="U2R64_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HEM8919348.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="U2R64_002587"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="U2R64_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HEM8919349.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="U2R64_002588"
     CDS             complement(4304..5215)
                     /locus_tag="U2R64_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8919350.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="U2R64_002589"
     CDS             complement(5232..6239)
                     /locus_tag="U2R64_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEM8919351.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="U2R64_002590"
     CDS             complement(6236..8365)
                     /locus_tag="U2R64_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8919352.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8493)
                     /locus_tag="U2R64_002591"
     CDS             complement(8370..>8493)
                     /locus_tag="U2R64_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8919353.1"
                     /translation="TGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1487 g         2679 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg gtt
//
LOCUS       DASHWW010000094         8342 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.094, whole genome shotgun sequence.
ACCESSION   DASHWW010000094 DASHWW010000000
VERSION     DASHWW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.094"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..752)
                     /locus_tag="U2R64_002592"
     CDS             complement(<1..752)
                     /locus_tag="U2R64_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919354.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDV"
     gene            complement(960..1886)
                     /gene="glsA"
                     /locus_tag="U2R64_002593"
                     /pseudo
     CDS             complement(960..1886)
                     /gene="glsA"
                     /locus_tag="U2R64_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
     gene            complement(1909..3120)
                     /locus_tag="U2R64_002594"
                     /pseudo
     CDS             complement(1909..3120)
                     /locus_tag="U2R64_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(3155..4768)
                     /locus_tag="U2R64_002595"
     CDS             complement(3155..4768)
                     /locus_tag="U2R64_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919355.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            complement(4880..5089)
                     /locus_tag="U2R64_002596"
     CDS             complement(4880..5089)
                     /locus_tag="U2R64_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HEM8919356.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            complement(6078..7292)
                     /locus_tag="U2R64_002597"
     CDS             complement(6078..7292)
                     /locus_tag="U2R64_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEM8919357.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            complement(7420..7890)
                     /locus_tag="U2R64_002598"
     CDS             complement(7420..7890)
                     /locus_tag="U2R64_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEM8919358.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            complement(7887..8129)
                     /locus_tag="U2R64_002599"
     CDS             complement(7887..8129)
                     /locus_tag="U2R64_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HEM8919359.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
BASE COUNT         2393 a         1767 c         1313 g         2869 t
ORIGIN      
        1 tagacatctt cttcttgtaa gtctagaatt cctttttgct cttccaatcc ttgacagact
       61 aattgaaata acggcttcgt ttctgcgctt ttcttatctt cttctttcag tccaagggga
      121 aatgcctttc ttccgattgc gatctctatt tctcgtatga taaaggactt ttcatcttcc
      181 gaatatcttc ttttaaaaaa atgagtctct acataatcaa tcaactcgtt acaagcttct
      241 tctacatacg gatttttatt ttcatagcct tcccaattga cataacgtac taaagctagc
      301 aagatgttcc gcgagtcaaa ttctgggata atgatttctt tatttttcaa ataatcattt
      361 tctttaaaaa aatccaatac gatttttttg attgtatata ctttactcaa agaaataaat
      421 tcaagatcag ccagttctgt actcgtgaat ataccattaa aataataact taaaaacttt
      481 aaaaaataag attgaccgta cagaaactgt gtgagctcag aaagagcaat accatgtttg
      541 aatacgagtt tatacttatg cttctctctt acttgttctt ttatacaata ttctagacac
      601 tcggctagac tttctagatc gtgaaggatc gttggtgtag tcacccttag agaaatagct
      661 gtttgttcga tgtctatttc ttggaattca aataattgtt cacacagata cacttttcta
      721 aatatatttc gctcgatgta attttccagc attcctgata cacgcctcca gtttttctta
      781 tgattttatt taatcatatc tgtaaatcgt atttttgttt cctttttatt tagaaaagcc
      841 ctttcaaaaa ccaataaaaa aagaaactgg gacaaaagtc aaacaagctc acaatttcag
      901 cctcattgta ggtagctttg agccgtttgg acttttaccc cagcctcttt caagaatggt
      961 tattcaaaga tgtcagcgtc tagttctttg actacatctt tcaacaattg gataccagct
     1021 gcgctgttac caaatggatc tagtgccggg ctgaagacac ctatgccgta acgatttggc
     1081 acagctgcca tcaacccgcc gcctacaccg ctttttgcag gtacaccaac atggacggaa
     1141 aactctcctg attcatcata caaaccagca gttgtcataa ttgatttgac gattgtagca
     1201 ctttcttcag taatgatttg tttgccattc caaggagcaa ttcctttatt tgccagcaca
     1261 gcagctaatt ttgctatgcc tgtagcggtg acattgaggg agcattgtct gaaataagca
     1321 tcgagtatct ccggtacgtc tccttagatc atttgattac ctttcatata gtaagcaaga
     1381 gagcgattga tatcacctgt tcttgattca gaatgataga tttcttcatt caatgtgata
     1441 ttaggatcat cacagatctc tttcataaat gacaagattc gctcaaattt ttcatctgca
     1501 tctttaccgg caatcaacga ggttgttgca atcgctcctg cattaacaaa aggattcatt
     1561 ggatgtttgc gatgattgat ttccatattc atgatagaat tgaaggcaaa accggttggt
     1621 tccgtgttga ttgtttgaaa gactttttct attccgttgt ctttgattgc taataacaat
     1681 acgggaactt ttgacatgct ttcgatggca aagcgcacat cggcgtctcc tccctcaatc
     1741 agttgttttg tatccaaatc ataaatcgcc atacctaatt gtttgggatc cacttcagct
     1801 aatgctggaa tgtaatccgc cacttgtcct gtttgataat agtggaaatt ttttccaatc
     1861 aattgttcta attcttttac ttccatttga ataaccagct ttcatttttt atttttctgc
     1921 atgctggaat ttatgacggc atgcgtagat cgtaaatgga ataactaaga cgataagata
     1981 agaaacaatc agaatcgttt cataaatccc atgctgtcca gctgcgatac tagcaggtgg
     2041 aacaaatgag atacaaaaag caaaaagtga agtcaaaaga cctaaacaag caacgattac
     2101 ttttacaact tttccgcctg gaacctgata ggctctttca agactgtcat ctttaaaaac
     2161 cagcttcaaa tagcccgcga aaaacataaa gtacaacatc aggtagatta caacagtcaa
     2221 tgacatcgct gcaagaaatg aaagattatt ccccccgccg cttaatgtaa agacggctgc
     2281 ccagattgtt gcaacgatcc catttgcgat catcaaatga gcaggaacac cgtgtgtgtt
     2341 ttcttttgca aaatattcag gaagtaatcc ttcttctgct gctacgtgaa gtgcttttga
     2401 aggagaggtt acccaagaag caatttctcc gatgacacct aaacaaacaa gaatcgcaag
     2461 aattttcgca atccatgcaa gatttggatc aatgtgtctt aataggaatt ctaacgattg
     2521 aatcacccct gtattaagag acaaaccatg ttgaggtact gtagtagcga cggtcaatcc
     2581 gccaaaagta tctaaaatga ttgccagaat aaccaataca aacattgcta atggataatc
     2641 ctttttaggg ttttccattt catttgcatg actggcagat gtttctacgc ccatatatgc
     2701 taaaataaag gaaacaaaaa caaccagcgt aggcaatttc gaaaaatcag gaatcaatgt
     2761 tttcatagac agtatcgttt gtagtggagc gcctgaagcg acataatgga tccctaagcc
     2821 aaacaagact aatgctggca acaagatacc agctacaaaa ccgatccgag caatcaatga
     2881 agtgtatttg gttcctttta actgtgagag taaaatagcc cagaaaataa tcaataggat
     2941 tgccaatttc agatatttat tgttttgtat agcaccaata cccgttgcat aggataatgc
     3001 accagttaag aaatacagca tggtcaagta gccaactgtt atctcaaacc attggaaaaa
     3061 gattgcggca aaaccgaatc gttttcccaa tgtgcgactg acccaagtat agacaccgcc
     3121 ggtttccctt agttaaaaat attactcttg ttgattactc aactcttcca ataaatcggt
     3181 aatatatctc aatttcctgt attctttcgt tatcctcatt cgttgttgct tcatgtatga
     3241 ggattttttc tatcatggca tttaataatg gtgctgtcag ttcctttggt acggaatatt
     3301 ccttgattaa ctcaatccac ttttcagcac ctatcatatc ctgttccatt ttacttagtt
     3361 cttctcttag gcttgttatc tgctgttcca gttctatctg ttctttttgg tacttgctgg
     3421 acaacatcac aaaatttcgc tctgttatct tctcacaggc tctatcttca tacattttcg
     3481 caaataaacg gtcaatctca ttttgtctgt tctcggcttt cttcaatgta cttgcctttt
     3541 tcttcttttc ccgtattctc tctgcattgc cagctttctg tatcttgttc aatacctttt
     3601 cttcgtcctg ctgtactgcc ttagcccaat actgcaagcg ttccaatacg gcttgataca
     3661 gcacatcata acgaatgtag tgcatagaac aattaccttt gccaaactgc ccgtagtaac
     3721 tgcaagcata ataactgtaa ggcgttttat ttgtcttatt cgttccaaat ctcatagacc
     3781 aaccacaatc cgcacacttg acaagccctg caaaaatcgg cgttgccttt tcctttgtct
     3841 gtctgcgtct tgattttatc tgctcctgca cacgatagaa cacttccttg tcaataatcg
     3901 gctcgtgagt gttttctact cgaaaccatt cactttcggg cttacgcact ttctttttgc
     3961 tcttgaacga taccgtagac tgcatattgt gaacactgtt tccgatataa acctcacttt
     4021 tcaatatcgc cttgacatga gcaatcgtcc actcataacg cttactttcg ggttttccct
     4081 caaagatatg tgcaaaagta ccgtatcttg taaaatttag ccatgacgct gtcggaactt
     4141 tttctgctct taactgcttt gtgatttttg cacttccgta accttgatag gctagggaaa
     4201 agattttttc aataatccat tttgtttcat catcaaccaa cagttttcct ttgatgtcag
     4261 ggtgtttctt atatcctaac ggagcataag caccgtaatg agccccctcc gcaaactttg
     4321 tcttaaatgc tgatttgact ttacggcttg tatctcttgc cacccattca ttgatgatgt
     4381 tcttaaatgg tgcaatctca ctttcgcctt tttcgctgtc tacaccgtca tcaatcgcta
     4441 tgtagcggac attatgacta gggaaataca attctgtata ttgtcctgtc ataatataat
     4501 ttctgccaag acgggaaagg tctttcgtta caacacagtt gatttttcct gcctctatat
     4561 cctcaatcat tctttgaaaa ctcggtctgt caaaatttgt tcccgaccag ccgtcatcaa
     4621 tatattcatc aatgacattc aaatgatgtt cttttgcata taaacgcaac atacttctct
     4681 gtgtggtaat gctggaactt tcgccctgta attcatcatc tcggcttaac ctaagataaa
     4741 gtgcagtatt gtaaatctgt tgtttcattg tcagttatcc tcctttataa ctaacccgtg
     4801 tttacaatac ctgcttgcaa gtaaagtata acacgggtac tttttgtcat tcaatctatt
     4861 tcttacaact gcaccgattt tatgcgattg tctgctttgc tttttccagc atgacatcag
     4921 ttagaagttc ttccattgtt ttgccctttt cggaaaaatg ctcttttact acaatctttg
     4981 tctttcctct gttgccaatg ccacacttgc catttttctt ttgaattgtt tttacagcat
     5041 tatcaataac acataccccc tttctgtaaa atctttctaa gcaattcaac ggcttttgtc
     5101 atagcccaca ggagttccac ctctgcatag ttcttatgta gccgtaccca ttgcgtgcga
     5161 cgctcttaat gctcaagctg tggctgtacg ggagtatcat tatctgacag tacaggtcat
     5221 ggcgataaaa gaggacaaat cttttacaag aacacaaata ggttttcgct cgctcttgca
     5281 ggggaaaggt cgtggcgtat ttgtttcaac ggctagctgt ctgtcaaacg tattgaatag
     5341 ctttattcag ttgtcaaaga acgattgaaa gaaaaaaatc gtctttccta tatatcgcgt
     5401 tggaaaagag gagaaacgta accaaaatcc aaaacttttt ccattattag tacaaatgga
     5461 acggttcatt ttggcaatca acggttgatt ttctcctttt tcactactat ctgtacagca
     5521 aacgtccatt tgctaagttt aaatggaaaa attttaactt cttttcatgc accatatagg
     5581 gatagaaaat gtcattttgc taagttgatg atgaaaaaag aatattttcc ttttcacacc
     5641 ctaactaccc aaaccatacc gttactgcca acaatagaat gaaatatttt ctttgcacca
     5701 tatagggaac ggaaacctta aattgttaag ttgagaacaa agtattttca tcttttcaca
     5761 tcaacactca actgctaatg cctgtttgaa tacaaaatga tgatgttttt cctcttttca
     5821 cagaagactg tccactaatc acgaatttcc gtcatttttt caaaactttt ttcttctttc
     5881 acttcatata gggacagcaa gccccgattt aatgacctat tttcaaaaaa agtttagatt
     5941 tccttttctc gcaccatatc tgtacgcaag tagccatttt gttgcagatt taataaaaaa
     6001 tttatttttc ttctttcact tcacataggg aatgaaaaca gctctttgct gactaaatct
     6061 gaaatttttc aattacatta aaaaataccg tcattctctt gtggaacagc ggtatctata
     6121 cgttcttcta tggttgattt ctctaattgt aataaatgtt tatgcttgtc ttttagttct
     6181 gcctgctcaa tcatatcttt cagtatcgtt gtacgatttt ctctgtctaa tgcctgtacc
     6241 atttttatgg ttggtgcgac ttgtctttgt agccaatgca acgctttttg taaagtgtaa
     6301 ggctctggct ttgtggttaa gcgtatcggc tctctgtttt cccctacaaa ccatgcccaa
     6361 tcatcatttg ttatccattg actttttggc ttgtcgtcct ctctgtcaac aaagcggaca
     6421 taatgattga tgatagaaaa agcggtgcgt tcagcgtccc gataggtcag taaatctaca
     6481 accgcataat aggctcgttc gttcttcatg cgtatttcaa aacggttctt aatctccgta
     6541 tcttcaattt ctgtgccatt cttgacatac tgctcataat ttttctgata agcacacata
     6601 tataattcgc tacttgttga accgagatat aaggtttctc ctgtattctt tggtaaatcg
     6661 ctaccgcatt tttctgtacc gctgtaatct ttctgcatac ggaagtagga catacattcg
     6721 ccagccttgt atttttcctt taactttgga atatccaata ttcctgcttt atcattgata
     6781 gccaaatcaa gccgtttcat cacaccacca gccgtcatac aatccagcat gaagtcatac
     6841 catgagcgtt cctgtgccag cagataacat tccatttgcc gacagccttt gcctttcagt
     6901 tccaataaaa cacctaaatg ctcctgcatg gaacacatga tattgatgtc gccaagtaca
     6961 tatttgcttt catatccgta ttttccataa tcttcataaa gcatgtaatt agatttcagt
     7021 tgtaatacat cacggataat cgccaatgcg tccgtagtag gaaagcggac acgaaagtaa
     7081 tcaatcaata agaatagtgg ttcttgcgga ttgaaacgct caatctgttt ttctatgatt
     7141 tctcttaatt cgtcattcaa tggctgtttt cctttttcaa tgcggttgta atattcacgg
     7201 ctgataccac aggcaacagc aagccttgtt tgtgttactc cgtattcctc acgcttttgt
     7261 cttagttctt caataaagtt tttatcattc attcttcaat tcctccaatc aaaaaaggca
     7321 actaccataa ttgataattg cctgtcatta aaaatctgta tagaaaaagc agtcaatcct
     7381 aagactaact gctttgtgtg tatggatata aaattgcttc taatcttgaa taggtatcca
     7441 aatttcaata actgaattat cactattcca atgaaaacga taatcgtatt tttcaaagtg
     7501 taggataata tcttttatag gaatatacga tgtactagga ataatttctt cataaatctt
     7561 gccataagtt tcatatattt tatccatagc accaatatgc tccacaacca aatatttata
     7621 agacggtatt tctttataca gaaagccctc tggggtaatg gttctttggg gaatagaaca
     7681 gaaataataa agttttccat ttcttctttc cataaaagca tattttaccc aatttcctga
     7741 ttgtgaaaga tacgcttttt tcaaactact gttaaacttt ctccaaaact gtgtactaat
     7801 ctgaatattc tttttttgat aattagtcag ttctacttcc tgcccaataa ctgcaaatgc
     7861 gtttaattcc tttatagaaa aatttatcat tttaccttgt gagcagtgat aacggtataa
     7921 ctgtacgcat ttaccgttat aatacaatta tcaatcgtta tataccagtt ttttcctttt
     7981 cttgtgattt ccgcattaga aaggctaatt ttttctttgc accattcaat tacattttct
     8041 acattcaaag ataagttctt tttaattcta ataacgccaa gttcagttgt gtgaagtctt
     8101 cctaagtttt ccagtaattc attttccata ttttgatacc tcatttttca gcaaatttat
     8161 ttgtatgttt tataccccaa ttataacatt ctcatatcag cactacaata aaaataatta
     8221 agcaccaata atcttattga acatctccaa ccgtaaatct ttcacaccat cagtgataaa
     8281 cactgagctg acagcaatta cgacaactac cataattgcc tgcacttaaa tttctgcaaa
     8341 ag
//
LOCUS       DASHWW010000095         8325 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.095, whole genome shotgun sequence.
ACCESSION   DASHWW010000095 DASHWW010000000
VERSION     DASHWW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.095"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(73..441)
                     /locus_tag="U2R64_002600"
     CDS             complement(73..441)
                     /locus_tag="U2R64_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEM8919360.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            612..1568
                     /locus_tag="U2R64_002601"
     CDS             612..1568
                     /locus_tag="U2R64_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEM8919361.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1641..1757
                     /locus_tag="U2R64_002602"
     CDS             1641..1757
                     /locus_tag="U2R64_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEM8919362.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(1812..3494)
                     /gene="recN"
                     /locus_tag="U2R64_002603"
     CDS             complement(1812..3494)
                     /gene="recN"
                     /locus_tag="U2R64_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEM8919363.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(3507..3962)
                     /locus_tag="U2R64_002604"
     CDS             complement(3507..3962)
                     /locus_tag="U2R64_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HEM8919364.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLQLPLS"
     gene            complement(4069..4887)
                     /locus_tag="U2R64_002605"
     CDS             complement(4069..4887)
                     /locus_tag="U2R64_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEM8919365.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(4896..5786)
                     /locus_tag="U2R64_002606"
     CDS             complement(4896..5786)
                     /locus_tag="U2R64_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEM8919366.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(5788..6012)
                     /locus_tag="U2R64_002607"
     CDS             complement(5788..6012)
                     /locus_tag="U2R64_002607"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEM8919367.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(6017..7354)
                     /locus_tag="U2R64_002608"
     CDS             complement(6017..7354)
                     /locus_tag="U2R64_002608"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEM8919368.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(7355..8209)
                     /locus_tag="U2R64_002609"
     CDS             complement(7355..8209)
                     /locus_tag="U2R64_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEM8919369.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
BASE COUNT         2380 a         1826 c         1371 g         2748 t
ORIGIN      
        1 tcataaacat ttttttaaaa atcaagctgc aaaaagcctt ttaaaagact ttttacagct
       61 tttctatttt tttcataggt aagaaagtat gttcacaatg atcaagacag cgtacaagac
      121 gattgtcaac agaaaaacca aacgccaagt catcttgaaa taacgcggat aaataatttc
      181 ttcataataa tatgcttgga aaacagcaat acaaattccc attagcaaaa cagaaataaa
      241 gaaaaacggt aagatagaaa ttgtccctgt atttctagac aatgcatgca taccgcccca
      301 caaaaaagga atcgccaaat caggggcttt tattttaaaa cgacgattta acgaaaataa
      361 ttttacaaga aattggcaac caaacaaaac gattaccggg taaatatacc aaaacaagat
      421 aagtggtgtg aatgtgccca tgaacgtaaa ctcctttttt atcgttgctt caagtatact
      481 gtatatactt tacacaactg tttcatttta tttaaattta tgcagttata ttctatatct
      541 tacaaacaca ttccatgtat tccaattccc tatccgttat aataaaagaa acaggcaaca
      601 ggaggaaaat catgatcaaa tattttacat tagataatga gaaactgcgt aataccggaa
      661 aggaaactga ccaaacgatc tggtattgtg tagaacgtcc taatcaagaa gagattcatc
      721 agctgacaca tcaatttgaa attccgtcag attacatcac ttccatattg gacgatgcag
      781 aaaattcccg tacagaagaa ttcaatcaat caaagttgac aaagccagcg ttattattgt
      841 tacaatatcc ttttgctaaa acaagtccta gcggttattt tcaagtggat acatacccgc
      901 tctctattat tttgacgccc aaaaagaagc ttatcacaat tacgaatcat gaaccactgt
      961 ttttaaagaa agtctttagc cagacctttc caaaaagtga tatttcgcct aatctcaata
     1021 tcttctttca attcatttgg caggtcacac tctcttacaa cagttattta gctacgcttc
     1081 aatctcaatg cgatactttg gaagccaaac ttcaagtatc cactgaaaac aaacaacttt
     1141 atcaaatcat ggatatccaa aaaagcctcg tttatttcag agaagcgact tctgctaatt
     1201 tagatgcatt gaaagaacta gcgcaaaata aacttttcca agaaaatcat gctttgaaaa
     1261 atcatttacg tgatgtattg gtggaaacag agcaggcaat gactacttct cgcattcaat
     1321 taaaactagt agaacaaatg aatcagactt tttcagcaat cgtatcgaat aatctgaata
     1381 atattatgaa aattttaact tctttaacga ttattttaac tataccgaca atcgtcggca
     1441 gtatctatgg aatgaacatt aagttaccta ttgctgaaag ggatgatgcc tttatatggc
     1501 tagttctatt aacattattt atttgtatcg taactaccta ttatttaaaa aaagggaagt
     1561 ttttataaaa aagccctctt gtggaaatgg aaaaaagatt gtacacttga atcaactaat
     1621 taatgacgag gttgaaaaca atgcgtgaaa aaaaacaaac aagtactttt gctaaagtaa
     1681 caaaatttgt catttggaca atgctgattt taacgattgg atctgttgta ttgactgctg
     1741 taatgagtgt catgtaaaaa taaaatatag ctatcagctg ctgaaaagga cctgaaccac
     1801 tgcgaggtgg ctcaggtcct ttttgcgagt ttcaatagtt cttttgcatg ttcgagtgtg
     1861 agttttgtaa tctcacttcc agccagcata cgtgcaattt cttcttctct ttcttttgtt
     1921 ttcaactctg aaacagaagt ttgcgtacgt ccatcaatca ctgctttcac aatataatat
     1981 tgatagtcgg cgactgcagc aacttgaggc agatgagtga tgcacaaaac ttgagagtat
     2041 ttcgatattt gagaaatttt atctgcgatg gcctgtgcaa ctcttccgct cacacctgta
     2101 tccacttcat caaaaataat acttgtcaca ccttgctcag aagaaaaaat agttttcaaa
     2161 gcaagcaaca tccgagacag ttcgccacca gaagcgactt tcaccaaagg cttcagtggc
     2221 tctcctggat tggtcgtaat gtaaaattcg atttggtcaa atccatcatg attcaattgt
     2281 ctattttctt cttttaagaa acgtacctca aactcagtgt tttccatata cagacttttc
     2341 aattcatgca gaatggattt ttccaattct tttgcgattt ttttacgcgc ttcatgaaga
     2401 tctgcggctt gttgctgaag tagaagctct ttttgctcta gttcctcttt cattttgtcc
     2461 aattgacctt ctgaaaaatc agaagaagct agctcttcgg tgatttcgtc atagtaagcc
     2521 aatattgact caatggattc gccgtattta cgtttcaact gtcggattaa ttctaaacgt
     2581 tgcgtaactt cttctaaacg actctcatct aactccaata aatcaatctg acgactcata
     2641 tcgccgattg catcttgcag caaatagtaa gcactttgga tattttcata aattgcttca
     2701 tactccacat ctagatgggc gatcccttgc agttctgaaa cggccaagcc aacaccatct
     2761 acactgtttt gttcattatt cgtcagtgct ccgtaacctg cagctaatcc atcagcaatt
     2821 ttttgataat tgctaagttt ttctctttct tcttttaatt tctcttcttc tccgacttgc
     2881 aaatcagcag cagctatttc ttcttgctgg aaatggagca tatctattct ctgaacatag
     2941 gatttttcat tttgctgcac ttttcgtacc cttttttcca gctcacgata agagatatat
     3001 tcttgctgat aactcttttt cttctgttgg aaagctacat ctccaaaacg atccaataaa
     3061 gcaagatgtg attcaggctg gagcagttcc tgatgttcgt tttgtccttg gatatctact
     3121 aaataactgc cgattcttct cagattagct aatgtgataa tatgaccatt cactcgacaa
     3181 acattttttc cagttaagga catatcccgt cgaacaatca gattgtcctc atctgtttcg
     3241 atccctaatt caaccatcag ttcagagaat ccttcttgtt ttggtagttc aaacaaccct
     3301 tcaagcacac atttttctgc tccttgacgt atataatcgc ttgaacctct tcctcctgct
     3361 aacagaccta aagcatcgat aataatggat ttacccgcac cagtctctcc ggtcagcgcg
     3421 gtcattcctt cgtgaaaaga aagccgcaat tccggaataa tcgcaaagtt agtaatactg
     3481 atttcttgta gcatcacatt cgctcctcaa cttaaaggta attgcaggaa gtctttcttc
     3541 aataaaactg cctggtcttc agttcgtgta atcatcaaaa cattatcgtc atcattgata
     3601 atcgaaaata attctttctt gtaacgttta tcaatcaaat ttgctgctgc cgaagcattt
     3661 cccggcaatg ttttcaaaat aacaaatttt tccatttggt caactgccac gaaagcgtct
     3721 tttaatagtt tttccaattt agtatttaca tcttcgtttg tttcagctgg tatgctataa
     3781 cggtagccgc catctgaagc cggtaccttg atcagtttca gttcctttat atctctggaa
     3841 atcgtagctt gagtaacaga tattcctttg cttttcagga tttcaacaaa ttcttcctgc
     3901 tttcggatat cttgctcact caacaatcga gtaatcaaac gatgccgatc tttttttctc
     3961 attacgtctt cgctccttag catattcttc ttaatcaatg atagcttatt tccttggtat
     4021 aataaagaag aatccgcata cttctcactt gattttcaca gttacaattt atttatggtc
     4081 aaactgttcg tgtgcatttg aaaccacttc tgccatatta atagctgaat tgattgttcc
     4141 gctttcgggt actttcctca agtgagccaa gaactcgata tttccttctc cccccgtgat
     4201 cggagaataa cttaattcca gcacatcata tccaccttgt gccgcaaatg acaaaatgtc
     4261 ttctaaaact ttttgatggg tctgagggtc acgaacaatt ccgtttttcc ctacagcttc
     4321 tctgcctgct tcgaattggg gtttgattaa agcaatcact tctccctctt cttttaaaat
     4381 agcatgtaat ggaggcagca tcagttttag tgaaataaaa gaaacatcga taacagcaac
     4441 ttctggaatt cctaaggtaa agtcttcggg ttttgcataa cgaaaattca ctctttccat
     4501 tacgacgact ctaggatctt gtcttatttt ccaagctagc tgattgtagc caacgtctaa
     4561 agcataactc atttttgcgc cattttgcaa agctgcatca gtaaatccgc cagtggatgc
     4621 accaatatct aacaatgttt ttccttcaac agatagatca aatgctttga gtgctttttc
     4681 taattttaat ccccctcgag aaacataagg aagtttttta cctttgactc ttaattcact
     4741 actcactgga attttttctc ccggtttatc aaaccgctcg tttttttcgt tgtaaatcaa
     4801 accagccatc actgaacgtt tggcttgttc tcttgtttca aataatcctt gtttgaccgc
     4861 taatacatct acgcgttctt tttccattct ttccctcatt tctccacatc aaattgcttg
     4921 atcatctggc gcatcagccc gccatcaaaa gaaaaaacgt cctcttctaa tttgtctatg
     4981 atcttgttgg cggataacag ctcaatctcc aacgcctcac gtgtcttttc taggcctaat
     5041 aaacgcgggt aagtattttt ttccatacgt tcatctttac cagctgtttt ccctaatgtt
     5101 ttcgttgtac caatcacatc gagtagatca tctcttatct gaaaagctaa acctaaatgt
     5161 tcggctaatc gttgaagtag caataagatt tcttcaggtt gcttcgctaa tatgccacca
     5221 gccagcaagg cataacgaat caaatgccct gtctttcttt catgaataaa tgctaattct
     5281 tctaaagaaa gctttttcga ttcgccctcg atatctgcag cttgcccagc aaccatacct
     5341 tgtgatcccg cacaaacagc taattgctga agcagcagaa gcttaggaga attacctaag
     5401 tgtgccatac tgattagctg gaatgctcct gtaagcaaac catctccggc caatatagct
     5461 aatgcttcgc cgaatacttt atgattggta ggttttcctc tacgaagatc atcattgtcc
     5521 atcgcaggca aatcatcgtg gatcaaggaa tacgtatgca ccatttctaa agcagctgct
     5581 acttgataga cgggaacatc aataggctca tcaaaggaag caacggccgt taaaagtaat
     5641 aagggacgta ttcttttccc gcctgctttc actgaataac tcatcgcatc atagagtcct
     5701 ctatccgttg tatgctcatc taaaaaagac aagatttctt tttctacagc aggtagatga
     5761 atagctgaaa agtcagttaa tctcatctca gctttcctcg tttccgtcaa aatcaacttc
     5821 ttcatttgat tctgtcatca ttttcgtcaa ggtctcttct gctttagcta atgtatcttg
     5881 gcaatgtttg cttaattcca ttcctcgttt aaacgaatct agagctgatt ctaatggaac
     5941 gtctccttgt tctaactgca tgacaatttt ttctaattct tgcagtgact cttcaaaagt
     6001 tggattttcc atatttttat tctcctttgt ctatctcttg tacttgtcct ttaacgattc
     6061 catcttgata atggatcgtc agcaaatccc cttgatgaat ctcggtgaca ctttttacta
     6121 cttgatcatt taacgtcgta tagctgtagc ctcttcccat gattttcaat ggactcaaca
     6181 aatcaagaga ttgaacagct tgagcaaaac gctgctgctg ttgtttcata tattgttgga
     6241 ttttctcttc taagcgtttt tctagataag cagtttcttg gcgagctgct ttaactcgat
     6301 aaagcggagc cacttgttcc aattggtggc ttaatgcgat cgtttgtttt tctttcgcat
     6361 gataaatttg ctgtgtagct tgatataatc gctgtttcaa ctggtctaat ttgatggtct
     6421 gaccttcata caatctttca ggctgccgaa atacatagga acgtcgagca cgctcgaacc
     6481 gttcttgttt gcgctggatc tggcgtacaa acgcctgctg caatctagct tgccgttctt
     6541 gaatgcgcat caactcttct gacaaaacag gaacagctaa ttctgcagct gctgttggag
     6601 tggcagcccg aacatctgct actaaatcag cgatcgtggt atctgtttca tgtcctacag
     6661 atgaaatcac cggcgtatta gcttgataaa tcgcccgagc aacccgctct tcattaaacg
     6721 gccataaatc ctcaatcgaa ccacccccac gaccgatgat cattgtatcg aaattgccca
     6781 tctcttctac tctctggata ttcctgacaa cattgtccgc tgcttggttt ccttgtacaa
     6841 ctgttgggaa caaaaccaat tggacaattg gatatcttct tttcaccgtc gtgatgatat
     6901 cgcggataac cgctccgctt ggactggtaa ggaccgcgat tcgctttggg aaacgtggca
     6961 gcattttttt aggcccttga aaaaggcctt ccttcatcag cttttctttt cgttcttcca
     7021 attcttgata taaagcacct attccatcag gctccatgtg ctctacatag atttgataag
     7081 aacctcccgc ttcatataat gaaatacgcc caacgacaag gactttcatt ccttcttttg
     7141 gctggaatcg taatttttgg aatgctcctt tgaacataat agcagatatt tttgcatggt
     7201 catcttttaa gctgaaatat tgatgggcat tggcacgtaa acggaaattc gatatttcgc
     7261 ctgttaaata tacgcgttct aaataaggat cggcatcaaa ttttcttttc aaatacttcg
     7321 ttaatgtagt gacagttaaa tattcttgtg ccatctattc acctgctcca aaagcttcgg
     7381 cagattttac ggtttgatac atcagcatcg tgatagtcat tggccctaca ccctttggca
     7441 caggagtgat ccagcctgca ataggctcca cttcatcaaa tttcacatca ccgatcagct
     7501 taccgttagc atcacgattc atccctacat ctatcactac agcacctggt tttacgaatt
     7561 cttttgtgac aaaatgtcca cgtcctattg ctacgactaa aatatctgct tcttgtgcca
     7621 gttcagccag attttcggtt ttagaatgag caacagtaac agttgcatct gccatcaaga
     7681 gtagctgagc catcggttta ccgacgatat tgcttcgtcc gataactact gctcgtttac
     7741 ccgccggatc gatagaataa gcttcaaaca ttttcatgat gccgtatgga gtacaaggaa
     7801 tcttgtccgg tttacccgca aggagtctgc ctaaattcat cggatgaaaa ccgtctacgt
     7861 ctttttcagg gcggatagct aacaggatct tttcttcatc tatatgcttt ggcaatggta
     7921 attggaccaa tataccatga aaactaggat cttgattgta tttttcaatt tctgcaagta
     7981 gttcgtcttc agaaatcgtc tcaggataac gctctaccaa tgaatggatt ccgatttctt
     8041 ttgctacacg ttctttattt cttacataga tttggctggc tggattttcc cctaccaata
     8101 aaacgactaa tccgggatgg ataccattat ctttcaattt ttggattttt tcagcaatct
     8161 ctgcctgcat tttttcagct aattcttttc cgttaatcaa ttctgccatc taaccactcc
     8221 cagatatttt ttgtgttttc attctaccat agaattttcc cgatttataa caggtttatg
     8281 atgattcata gaaaaaagct aggacttacg ccccagcttc taatt
//
LOCUS       DASHWW010000096         8066 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.096, whole genome shotgun sequence.
ACCESSION   DASHWW010000096 DASHWW010000000
VERSION     DASHWW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.096"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..721
                     /locus_tag="U2R64_002610"
     CDS             <1..721
                     /locus_tag="U2R64_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919370.1"
                     /translation="KGLTATDFANSIVHFPQNLLLLDPSASAGEYESHTGLKVIRGTE
                     NIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISELLYFGHMKTHLHSPFFYKL
                     QNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKINVKKSFFKKETPVEKISV
                     ELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIWKLKGTRYREEEIIATLIY
                     SVTDRHWQLVEDADLSYLPLK"
     gene            complement(802..1371)
                     /gene="thiT"
                     /locus_tag="U2R64_002611"
     CDS             complement(802..1371)
                     /gene="thiT"
                     /locus_tag="U2R64_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEM8919371.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(1437..1539)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(1545..2516)
                     /locus_tag="U2R64_002612"
     CDS             complement(1545..2516)
                     /locus_tag="U2R64_002612"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEM8919372.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(2610..3983)
                     /gene="glmU"
                     /locus_tag="U2R64_002613"
     CDS             complement(2610..3983)
                     /gene="glmU"
                     /locus_tag="U2R64_002613"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEM8919373.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(4486..5304)
                     /gene="purR"
                     /locus_tag="U2R64_002614"
     CDS             complement(4486..5304)
                     /gene="purR"
                     /locus_tag="U2R64_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEM8919374.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(5471..6295)
                     /locus_tag="U2R64_002615"
     CDS             complement(5471..6295)
                     /locus_tag="U2R64_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEM8919375.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(6268..6948)
                     /locus_tag="U2R64_002616"
     CDS             complement(6268..6948)
                     /locus_tag="U2R64_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEM8919376.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(6971..7909)
                     /locus_tag="U2R64_002617"
     CDS             complement(6971..7909)
                     /locus_tag="U2R64_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEM8919377.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
BASE COUNT         2313 a         1735 c         1403 g         2615 t
ORIGIN      
        1 aaaagggctg actgctactg actttgcaaa cagtatcgtg cattttcctc aaaacttgct
       61 cttgcttgat ccatctgctt ctgctggaga atatgaatcc catacagggc tgaaagtaat
      121 ccgtggtaca gaaaatattc agcgtttctt ttcctcttct cgtaacaggc gtggattcga
      181 tgaattgaag tggatcgact ttactgattt aacgatgctg aaagaattga cacctttaga
      241 aatttcagaa ttattatatt ttggtcatat gaaaacacat cttcattcgc cgttttttta
      301 taaactacag aataattttg tatacttcga tcttaatgat cagctgaatc ggatttatta
      361 tcgctattta gatgaatttt ataggatttt tgctagtaaa ttaagttcga tcttgtcaga
      421 taagatcaat gtaaaaaaat cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt
      481 ggaattattg aaagaaatgc gtaatttgat gcaggaaggg atcatttttt cttttgatca
      541 agttggtttg atcgatggta aatatcgtat cccaatctat gtgattgaag attatatttg
      601 gaaattaaaa ggcacccggt atcgagaaga ggaaatcatc gctactttaa tctactctgt
      661 caccgatcga cactggcaat tggtagaaga tgccgatctt tcttatctgc cattgaagta
      721 gatctatttc ttatcaaaaa ataaaaagga aacaagaaac taggacatga ttctgtctca
      781 agtttcttgc ttctttttta tttacagctc ctgtcgttta tctggcacaa aaatcgaagg
      841 agtcgtttgt tggatcccta ataaaacgat gatcgttaca atagctgtac tcaacccgct
      901 ggcaccattc attacgaaag aaaagagcca agaattcatc ccccatagtg catacgctcc
      961 ccagaaaacc actcctgcaa taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc
     1021 accaaacacg atgctttttc taatttgttt cgtattatcg tctacatagc ctttttggac
     1081 atttgaagcc atgagccctg ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa
     1141 cacttgaacg acacttaaat aataaacttg tcccaacgga aaatgtagga tgccccaaat
     1201 gaaacctgcc agcatccctg cctttgtccc tcttcttaac gcaaaaagag tcaatggaat
     1261 ctgccctaat gaaatagaaa aactactgcc gatctggatc ggaatcaacg acaacaccat
     1321 cgctaacgct gcaacaatcg ttccttctac ccaaactcta ttttttccca taaaaaaact
     1381 tcctcctttg aataaaaaag tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc
     1441 tgtttattca caattcctac gctcgcataa ccgatacagg tacgaagggt ttagaaatag
     1501 attcaatctc agcccaattg gactcccctt tgtgagttta tttattattt attttttgtt
     1561 tcaaacaatg gactaactgg tttgttttca tggatacgtt tgattgcatc tcccattagt
     1621 ccgccaacac ttacttcatc gattttgtcg attttacgat cttctggaag atagatcgag
     1681 tctgtaacaa ctagacgctc gatagctgaa tcttctattc tttgtaaagc agggccggat
     1741 aatactggat gtgtacatga agcatacaca ctagttgcac cagcttcttt caaagcattg
     1801 gcagccaatg tgatcgtacc tgctgtatcg atcatatcat cgatcagtac acaagttttg
     1861 cctttgactt gtccaatgat attcattact tctgcaacat ttgcttttgg acggcgtttg
     1921 tctatgatcg caatcggaga tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca
     1981 ccatggtctg gtgaaacaac gacaacatca tcgcctttga ttcctttttc taagaaataa
     2041 ttggcaataa gtggcgcacc catcaaatga tcgactggaa tatcaaagaa accttggatt
     2101 tggactgcat gaaggtccaa agtcagcatt cttgttgcac cagctttttg aatcatgttt
     2161 gctactaatt tcgctgtgat tggttcccgt gcacgtgctt tacggtcttg acgcgcatag
     2221 ccataataag gcatgactac gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc
     2281 atgatcagca actccatcaa gttatcattg actgggctgc tcgttgattg aataacatag
     2341 acatgcgatc cacgaatact ttcttcaatg tttacttgaa tttctccatc actaaattga
     2401 gtaacagatg attttcctaa ctcgacgccg actgctgctg caattttctc tgctaatggg
     2461 cgattggaat ttaacgcaaa aatttttaat cttgggtcaa agtaatgttt tgacatgggg
     2521 acctccactt tctttttcac aactctagaa ttctacctaa taaatagtag tcatattttt
     2581 taaataaatc aagtgatttt gcaaaagtct tagtttagat aagggagttt ttttgcatat
     2641 ccttctttat tgacttgtct tgctctcgca attgccagcg catattctgg aatattgtct
     2701 gtaattgttg acccggcagc aatcgaactg tttttagcta cctcgacagg tccgatgata
     2761 ttcgtgctag aaccaataaa gctgtggtcg ccgacagtcg tatgatgttt gttctttcca
     2821 tcatagttga cgaagacaac accacatccg acattgattt cttctcccag cgtagcatca
     2881 ccaacataag tcaagtgacc gactttagtt cctttgccga tttgagcatt tttcacttcc
     2941 acaaagtttc cgatatggac gttttcgcca atttcagctt ttggtcgtaa atgtgcataa
     3001 ggtcccacat ctgcatgttt cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg
     3061 acgtgatcct caatcctact gtctacgatt tttgaatgtg acccgatgac acaatcagaa
     3121 ccaatgactg tatttccttg gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt
     3181 tctacgcctg catcgatgta tgtcgttgct gaatcgacaa agcttacgcc attgaccata
     3241 tgcatctggt taattcgctt tctcatgatc tcatttgctt tagctaacgc gatccgatca
     3301 ttgactccca ttgattcttc aaaatcatcc gtttgataag cagcaactgt atggccttct
     3361 tcttttaaga tttcgatgat atctgttaga tagtattcac cttgagcatt gtttgttcca
     3421 actttgctta acgcatcgaa caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt
     3481 tcttgtacaa gagcttcttc tggtgttgca tctttttgtt ccacgatttt ttctacgatc
     3541 ccaatatggt cacggatgat tcgtccatat cctgttgggt tttctgcttg tgccgtcaag
     3601 atcgttgcac ttgcattttt tccttggtga tattcaaaaa gattgttcag cgtttcagta
     3661 gtcaataatg gtgtatcgcc actgataact aacgttgttc ctttttttcc ttccaagaaa
     3721 gaagcagctt gcaaaacagc atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta
     3781 ctgcgttctc ctagttgtgc tttaacttgt tctgctccgt gtccaacgat cgtaatcact
     3841 tcatctggtt tcgtttcact gacccgatta atgatatgtt ctaccatagg tttaccagaa
     3901 acgggatgta aaactttata taattttgac ttcatgcggg tacctttccc tgccgccaaa
     3961 ataattgcat aacgtgcgtc caactgcgtc actcctaaat atagtttgct gatttcagtt
     4021 tatcccagta tacccatttt ttcaacaaaa caagtgattt tcttttatcc cagcgttttc
     4081 tggataaaaa aatagataga ccataacggg cctatctatt tggtaaccgg tgctctcctg
     4141 ccaactcctc ggtcacaagt cacactactc ataaaacatg aaaagctgtt ttttgaaatc
     4201 gtttcttgtg acttagagtt aaacggtagg cttacaacct cttcattaaa cgtttttcaa
     4261 tcagctgacc ttcggtatta gctcaataaa cggcaaaata tgaggagcaa tttttccgtt
     4321 tattgagcta atactcagga caggacgctg atttcacaac ctctagataa acggtgttca
     4381 aaagccagtt tctcggtatt aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca
     4441 aaatttttct tactactcga aactaagcgg ctttttcaca acctcttatt ctgaaaaata
     4501 atttcctggc acaaccgtaa tatttttcgt ttgagtatct acatctttga cataaagcag
     4561 tgacgtataa tcatcgatgg cgcgatgacc gttgaatttt gattcggcaa atacagtgat
     4621 gccaacaagt tctgattcga attcttcaat caagctcttc attccgttga ctgttccgcc
     4681 gcctttcatg aaatcatcca ctacaaggac acgtgaacca cgtttcaaac ttctcttaga
     4741 cagttccatc ttttcaattc tttcagaaga tccagacaca tagttgacac ttactgttga
     4801 tccttctgtt atttttgagt cccggcgtac aataacgaat ggcgcattca gataatagga
     4861 cacagcttgg gcaataggta cgccttttgt ggctacagtc attacagcat cgattttttc
     4921 accaaggtat ttagaagcaa tgattcttcc aacttgacgc agcagttcag gttctcctaa
     4981 caaatcagag agataaacat atcctcctgg aagcagacgg tcttgttctg atagacgttc
     5041 tgctagagat tcaatatatt ttttcgcctc ttcatatgaa atttcaggga tgaacaatac
     5101 accacctgca gcacccggga ttgtttccaa ggttccatac cctcgttctt taaatgtttt
     5161 cttgatgatt cccaaatctt cactgataga agatttagca gattcataac gttcggcaaa
     5221 gcttgttaag gaaatcaatt catgcgggtg attcaataaa tactgtgtca tgtcaactag
     5281 acgttcactg cgacgtactt tcacctattc caactccttt taagaaattt tatcgtttta
     5341 cattatataa gtttttcttc aaaaattcga gcattttatg aaaaaataag aaaatagttc
     5401 ggtatttatt aaaataaaaa gaagcctata aaaaattttt cgtttttata aggcttcttt
     5461 tctttataat ttagttattt tttcttctga aggcaaccaa tattcgtttg atgatattta
     5521 caatcaggaa caaagcaata aagactaatg tgattgttgc tcctggaggt gtatctagat
     5581 aaaacgagct agttagtcct gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa
     5641 tcacgacatt gaagcttttg cctaatcgca taccgattgc tgcgggaaga accatgattg
     5701 cggatatcaa aagtgcaccg gcaatcggga tcatcacagc aatagccaca ccagtaatca
     5761 cattgaacat catcgacatc aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat
     5821 caaaagtcag aacatacatc ggccgtttga ataaaaagaa caatataccg atggcaacga
     5881 ataagattcc taaaaagatg acttgctccc atgtaatggt cacgatcgaa ccaaacagat
     5941 aggattggat acttgttgct gaattccctc cgctcaaatt catcaatact aacgctagcg
     6001 ccaaaccacc agccattaaa atggcaatgg agatttctga ataggttcgg tagatcgttc
     6061 gcagatactc caatatcaca gctgctaata caacgactag catggtcgta agtgtaggat
     6121 taaggttcaa aaagaatcct aacgctaccc ctgctaaaga gacatgagaa agcgtatcag
     6181 ccatcagcga ttgtcttctg atcactaaaa acacacctag catcggggcg attccggcaa
     6241 tgaagatagc ggcaagaaac gctcttctca tgaattcata tgaaagcaac gccattgaga
     6301 atcctccttt ctcaccagtc ggatctgtct gtccgcatac tgtttgatat cttcatgatc
     6361 atgggtgatc attagaactg atttcccatg gacatgcgca ctatgtcgga gaagacgata
     6421 aaattcattt ctggattctt catccatacc tgttgttggt tcatcaagaa caaataagtc
     6481 agggtcagta gcaaaaatac gcgctaaact gattcgctgc ttttgtccgc cagacaattc
     6541 acctattcgc cgatttcgca tatcccacat ccctacagct tctaaagcac gctgtacatg
     6601 ttgatgatct ttttcagaga gacgcttgaa ccagcggcct cttggatatc ttcctgaacg
     6661 gactaattcg atcaccgtac taggaaaacc tgcattgaaa gatgcaactt gttgaggaat
     6721 ataaccgata cttaattttt ttccttcttg atttttctca gcaatcttta tcattccttt
     6781 tgaaggtttc agtaatccta acgatgcttt caccaaggtt gacttggctg ctccattttc
     6841 tccagttaaa atgacaaatt cacccgcatc tacatgataa gagacatctt ctagtacagg
     6901 ttcatcatca tagtaaaagg tcaaatcaga tatttcgata taacgcacct tacaacctcc
     6961 attctaaaac ttaattgata ctttctttta aagctttcag atttttttcc atgacagaaa
     7021 tataattttc gcctgctttg atttgttcat tagtcaagct ttctaaagga ttcaacactt
     7081 ctagcttcac tcctgtttca ttcgacaatg tctcagctac cttcgaagag gcattttctt
     7141 caaaataaat cactttgatg ttgtttttct tcacaaattc ttttagctca gctaagcgac
     7201 ttggtgtggg ttcctgatct ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt
     7261 gattcgctaa ataagcaaaa gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt
     7321 ttagctcatc ggagtatttt tgatccagtg cttcaagctt tttgatataa gcatcggcat
     7381 tcttcgtaaa agtttccttt ttatctggat atttttcgcc taattcttca gcaatcgttc
     7441 tgacttcttt tatagctaat accggatcga gccaaacatg tggatcgtat tcatgtgaat
     7501 gaccatgccc ttcttctgat tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga
     7561 ttcctttagc tgcttcgatc atcaaggtct gtttgctatc cactgaatcc tttaacgaat
     7621 ccacaaaaaa ttccatgtct gaactattat acacgaaaac atctgcatcg gaaatttctg
     7681 ctctttcttt tgcacttggt tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt
     7741 tcacgtttcc ttcatcccct acgatctctt ttgtaaaatc atacatcgga taaaaagtcg
     7801 taacgatcgt caaatcctct tttttgtctg cttccttgtt cgtatttcca catgctgcaa
     7861 acagtaaagc acctatcatt accgtagctg tcaaaagata ttttttcatt tatatgctcc
     7921 tttcaatgaa caaatcggaa ttttacgatt tattaacgtg aactaatgta tcaaaataaa
     7981 aaaacacagt caatagaaat ccatcaattt ctgatttaag catgtatatt cttgattaaa
     8041 tcgtaaaatg gatgagttgc tgctca
//
LOCUS       DASHWW010000097         7949 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.097, whole genome shotgun sequence.
ACCESSION   DASHWW010000097 DASHWW010000000
VERSION     DASHWW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.097"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            143..847
                     /locus_tag="U2R64_002618"
     CDS             143..847
                     /locus_tag="U2R64_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8919378.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1075..1413
                     /locus_tag="U2R64_002619"
     CDS             1075..1413
                     /locus_tag="U2R64_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919379.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            1398..2252
                     /locus_tag="U2R64_002620"
     CDS             1398..2252
                     /locus_tag="U2R64_002620"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEM8919380.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            2399..2632
                     /locus_tag="U2R64_002621"
     CDS             2399..2632
                     /locus_tag="U2R64_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEM8919381.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            2830..4734
                     /locus_tag="U2R64_002622"
     CDS             2830..4734
                     /locus_tag="U2R64_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEM8919382.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISVGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPTEKVKIS"
     gene            5088..5453
                     /locus_tag="U2R64_002623"
     CDS             5088..5453
                     /locus_tag="U2R64_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8919383.1"
                     /translation="MTAEVCTTTCIHKEKVASVKNNLKDKDLSTLLVLGKCFSDSSRI
                     KIFYALETYKEMCVCDLAAILNASIATTSHHLRFLKKNGMAKSRQYGKVVYYSLANEE
                     ILSAVQAFLKLSENSSMKA"
     gene            5470..6081
                     /locus_tag="U2R64_002624"
     CDS             5470..6081
                     /locus_tag="U2R64_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEM8919384.1"
                     /translation="MLQNILSALAVYISTSIDYLFILLIIFSQNHTKKGLRQIFFGQY
                     LGTGILVAISLFAAYVLNFIPQDWIIGLLGLIPIYLGIRVAFVGEEEEEEGEVVEKLG
                     SRGTNRLFWTVSLITIASGGDNLGIYIPFFTSLSFSEIVTSLIVFAISVAVLCYISYK
                     FAKISFVSETLEKYERIIVPIVFIGLGIFIMIENGTIQTILGL"
     gene            6109..7770
                     /locus_tag="U2R64_002625"
     CDS             6109..7770
                     /locus_tag="U2R64_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEM8919385.1"
                     /translation="MSENKKYHEWILEGIDCANCADKVERGVAKVAGVANSSVNYMTE
                     TLSFEVTEEKEYLVLSNVQQKVKKLEPDITLKNKVDGRLIEINPALIKKSNLKDDKKN
                     YEWILEGIDCANCAAKVERGVATVPGVTNSSVNFMTETLSFEVAGENKTDVLASVKQT
                     VGTLEPDVVLRKKSDGTLIEHGTDSNKNSTSNKSISDKDETNQKQTNRAYLASLLGNK
                     TKITLIRLILGLGILATGIFLPMDGQASLGLFILAYLITGYDVVGRAIRNIFRGQVFD
                     ENFLMTIATLSAFYIQEYPEAVAVMLFYQVGEVFQDIAISKSRRSIADLMDIRPDYAN
                     LVTGNNVEKVAPEAIKIGNIILIRPGEKVPLDGKVVEGASAMDTSALTGESVPRSVKP
                     EDTILSGFINKNGLLKVVVEKPFSESTVKKILDLVQNASGRKAPTEQFITKFSRYYTP
                     IVVIAAALLAIVPPLLVPGATFNEWIYRASIFLVISCPCALVVSIPVGFFGGIGSASR
                     KGILVKESNFLEGLNDLKYVVMDKTGTLTKGFCCKVLNLLSNKVE"
     gene            7798..>7949
                     /locus_tag="U2R64_002626"
     CDS             7798..>7949
                     /locus_tag="U2R64_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8919386.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     MTIYRWV"
BASE COUNT         2509 a         1296 c         1772 g         2372 t
ORIGIN      
        1 taaaagtaga agctgattta gggattggaa ttctttccag tcctttttcc attttcttga
       61 tgtgcatcaa tttttttgta gtaagagact tatataataa aagcagcgaa tataaacaaa
      121 ataaataaag ggggagaatg aattgactaa acatacccat catgaaattg gcgaccacgc
      181 agcctgtatc cgcttggttc caatattcaa tcacttagag gatagcgcga tgaattacat
      241 tgctgaaaaa gcccacacga aacagtatca aaaaggagag tttctgtttc gttcacaaga
      301 aaaagaggat actttatata ttatcaatcg tgggaaaatc cgtatttatc gattggcaga
      361 ctctggcaaa gagcagctag tgcggatctt gaaccctggt gatttcaccg gagaatggac
      421 cttgttcaac ccggatgcag tacacgagga atatgccgaa gcaacccgag ataccgttgt
      481 ctgtatgatt cagcaaaaag atgtccaaga ttttctggaa caatacccag ctatttcttt
      541 aaaactattg gcggaaatgt ctaaacggtt agaaagttca gaacgtcaaa cgacacaagt
      601 agccgtggag agtgtcatta cccgtttagt tttgtttttg gcagaaaatg tggaacctga
      661 aatgggcaac tctcccacca tcaccctgcc gatggcaaaa aaggacattg cttcctattt
      721 aggaacgaca cctgagacca tcagtcgcaa atttggagaa ttggaggacg aaggattgat
      781 tcaacagctg tctgggaaaa ggatcaagat tcaggattta gatgatttat tgctttacag
      841 cgaataatcg gacacacttt tttctacacg ttggtgttct gtcgctcttc attaacaacg
      901 ggacagaact cagtgctttt gcttccatct gtccgttttt ggctttttta agacagaacg
      961 accttcattc attggaaaaa taaaagcaca aacatgataa ccctcaagtt tttttgtttt
     1021 atttttcttt aagatagggt tgtcgaacaa aacgtaaaaa taagtagggt gaatgtgcat
     1081 tgtttttggg tgatagttgc catcacgttg tcagcagcgg gggcattctt tgtcgtccct
     1141 ttcaccaaga acacgattgg cggcgaagca aaaacgtcta acgttgttga ggcagatagg
     1201 ttagctatgg aaaaagaaga ggaagttgta aaaggagccg gcgtaatcgg acacggaaaa
     1261 gtggcgtatt acgaagcgag tgaccaggga gataaaagtg tattcactgt ttggtttcca
     1321 tggagcttag ccggaatctt gttcagcatc accatgacta gaatgacgcg aaaaattgaa
     1381 gaaatggagc aaatagaatg ggattcgtat taggcgtttt gaatccccat gtggtggaga
     1441 ttggttctgt tgtgattcat tggtatggag tcattattgc agcgggcata ttagcggctc
     1501 tccagttgag caccaaggaa gcaaagaaaa aaggactgga agaggatacc attatcgata
     1561 tggccttatg ggcaattccg attggactcc tcggcgctcg gctttattat gtgttatttg
     1621 aacttggtta ttatctgcaa aatccaggac aaatccttgc gatttggaat ggcggcattg
     1681 cgatttatgg gggattgatt gcaggagggg gtacgctata ttggtatgca aagaaaaaag
     1741 gtacttcttt ggcactcgtt cttgatattt tagcgcccaa tgtattgtta gcccagtcca
     1801 ttggtcgttg gggcaatttt atgaatcagg aagctcatgg tgggccggtt actcgtcaat
     1861 tcttggaaaa tctttattta cctgaattta tcattgaaca aatgaatatg aatggtacct
     1921 actaccatcc gactttttta tacgagtcat tgtggagttt gttgggcttt gtcctcatcg
     1981 tcactatacg gaaccgaaaa cagcttttgc gtcaaggaga agtcgctttg agttacgttt
     2041 tgtggtactc agtgggtcgg ttcttcattg aaggtatgcg aacggacagt ttatggattg
     2101 gcgagtggat ccgcgtttcg caagccttgt ctctggccct gtttattggc gcgattgtag
     2161 tatggtttat acgcagacaa gattatccac caatttctta ttattctgat ggcaataagg
     2221 ggcagaaaaa gactattaag atggtgaatt gagcaaaaag ataaaaagaa gtgcaaaact
     2281 tgatatgcgt caattttcgt ttgctaaaag tgagctatac tacagttgta aagaggaaaa
     2341 ggcagtgttc attaatctgc tgccgataaa ataaaaacac ataaaggaga taggaattat
     2401 ggaaaaagct atattgcaat tagaaacgtt gtcttgtcca agttgtatgc aaaaaattga
     2461 aggtgccgtg aaatcagtta acggtattga taaagacagc attaaagtat tattcaactc
     2521 cagcaaagtc aaaaccaatt ttgattcagc tgtcacttcg attgaagaga ttcaaaaagc
     2581 tatcgaaaac gtaggctatc cggttcttaa agcaaaagtc aaggccgttt aacagattaa
     2641 atgaactagg caattctgga agaaaagcta tttttccagg attgcttttt ttgttgcaat
     2701 ccgattcgag gtgcttagaa acgataaaag agaactttct aaacttgatg tcagtcaatt
     2761 aattacttag gcaattatct tatactgtgt ttatcaataa aagagaaatt aaatttggag
     2821 ggaaaaagca tgcaacaata tatattaagc aagaaaaatg ttatcaccgt catcagtgga
     2881 ttgttaatcg tactcggttt cttcagtcac tttgttttag aaaacgtagg actttcagag
     2941 tggtctttga tcatcgcctc tgtctttggg attacgccaa ttgccattca agcgtttcaa
     3001 gcaatgaaag tcaaagtcat cagtattgat gtcttagtca gtattgcagc gattggtgcg
     3061 ctttttattc aaaattatga agaatcggct attgtcacgt tcttattctt attcggacac
     3121 tacttggaac aacgaacatt gaaccaaacg cgatctgcta tcaaagaatt gactgaaatg
     3181 gcacccgaaa gcgccttgaa acaaatggat aatggcgaat ttgaagaagt agaagtggat
     3241 gatatagatg aaggggatat cttgctcgtt aaaacgggtg cgaaagttcc agtagatggc
     3301 atagtcctta cgggtgaagg gcatatcaat gaagctagca ttacaggtga agctattccg
     3361 gtcaacaagc tagctgatgc agaagttttt gcaggaacca ttttagaaaa cggaacgatt
     3421 caaatcagag ctgaccgagt tggtgaggac accacatttg gaaaaattat tgaactcgtg
     3481 gaagaagcac aagattctaa atccgaagcg gaacggttca ttgatcgctt ttctaaatac
     3541 tacacaccag ctgtcttggt tctggcaatt gttgtatggg cgttcagtca aaatattgag
     3601 ttagcaatca ccatcttggt tctaggttgc ccaggcgcat tagttatcgg agtgcctgtc
     3661 tcaaacgttg ccggtattgg gaatggtgct cgtaacggtg ttcttttaaa agggagtgaa
     3721 gtcattcaag acttcagtaa tgtggataca attgtatttg ataagacagg tactttaact
     3781 gtcggaaacc caaccgttgc agcgactgaa ctgtatgaaa aagatcctgc tgaaacgctt
     3841 ggctatctgg ccagtgtgga acgggaatca gatcatccat tagcaaaagc ggtcttaaat
     3901 caaattggag aaacaaactt ttatcctgtt gaaggaactg aagttgtgaa aggcggcgga
     3961 atcgtttcaa gtgtagctgg acatagagtg gctgttggga atgtggcctt gatggaaaaa
     4021 gaaaatgtca ctctcagcaa aaaagtgcaa aaagatgtca aacggtttga acaacaaggg
     4081 aactctctcg ttttgacagc ggtcgacggt gaattaaaag tactgatggg cattcgcgat
     4141 caagtccgtc cgggtgtgaa agctaatttg caggaattaa aagacttggg cgtgaaaaat
     4201 ctagtcgttc tttcaggaga taaccaagga accgttgatg tggtcgccgg cgaacttggt
     4261 ttgaccgaag ctcacggcta catgttgccg gaagacaaat cggcttatat cggaaaactt
     4321 caacaacgtg gtcaaattgt agcctttgtt ggagatggcg ttaacgatag tccgtcctta
     4381 gctttagcag acattggaat cgcaatggga agcggaacgg acgtagcgat tgaaacatcc
     4441 gatgtcgttt taatgaactc gaacttcagc aacttgcctc acgcattagg attagtaaaa
     4501 gccaccgcaa ataatatgaa acaaaatatc gtgatttcag ttggagtagt gttggtcttg
     4561 ttgaccagcg tcttcttcag cgaatggatg aatatgtcta tcggaatgtt ggttcatgaa
     4621 ggtagtatct tggtggtaat tttcaatggc atgagattaa tgaagtataa gttgaaaggt
     4681 cggaaagaac aaaaagaagt atcagcacct acagagaaag taaaaatatc ttaagaataa
     4741 attagaagag gctgagacaa tagtccatcc ttgaaatgac aaaagcggaa actcagattt
     4801 ttaaatctgg gattttccgc ttttttgagt tcttgaaaaa aaataagagt atagagtatg
     4861 ttctttataa aattaatttt cgtgtaaatt attaaaaatt taataataaa atttaaattc
     4921 ctattaagtt gtaacacatg aaattgctta aaatagtgta tcaaaaacct tgttttatta
     4981 atgttgaatt tatttgaaag gtctacagat taacatatta ttgacaaaac aatatttaaa
     5041 tagttatact tcattcaaac gtctgtttga acgaggtggt gaagttaatg actgcagaag
     5101 tatgtacaac tacttgtata cataaagaaa aagtagctag tgttaaaaat aatttaaaag
     5161 ataaagacct ttcaacttta cttgtattag gaaaatgttt tagcgattct tctaggatta
     5221 aaattttcta tgctttagaa acgtataagg agatgtgcgt ttgtgattta gcagcgatac
     5281 ttaatgctag tattgctaca acgtcacacc atttacgttt tttgaaaaag aacggaatgg
     5341 cgaaatcacg tcaatatgga aaggtagttt attactcttt agcgaatgaa gagattcttt
     5401 ccgctgtgca ggcttttcta aagttgtcag aaaatagttc tatgaaagct tagtttggag
     5461 gtagttattt tgttacaaaa cattttatca gcactcgctg tatatatttc taccagtatt
     5521 gattatttat ttatcttgct gattattttt tctcaaaacc atactaaaaa aggtctccgt
     5581 cagatttttt ttggtcaata tcttggaaca ggaatcttgg tagccataag tttgtttgca
     5641 gcatatgtgc taaattttat tcctcaagat tggatcattg gtcttctggg actaattccg
     5701 atttatttag ggattcgtgt tgcttttgtg ggcgaagagg aggaagaaga aggggaagtc
     5761 gttgagaagc taggatctag aggaacgaat cgtttgtttt ggacagtttc cttaataacg
     5821 attgcttctg gtggcgataa tttagggatt tatattcctt tctttacctc gttatctttt
     5881 tcagaaattg tcacttcttt aatcgtcttt gctatctctg ttgcggttct ttgctatatt
     5941 agttataaat ttgcgaaaat ttcttttgtc tctgaaacac tagaaaaata tgaacgaatc
     6001 attgtaccta tcgtatttat tggattaggg atttttatta tgatagaaaa tggaaccatc
     6061 caaactatat taggtttgta gagatcttat tagtaaagga agcaaacgat gagtgaaaat
     6121 aaaaagtacc atgaatggat attagaagga atcgactgtg caaattgtgc agacaaagta
     6181 gaaagaggcg tcgccaaagt tgcaggtgtt gccaatagta gtgtgaacta tatgacagaa
     6241 accttgagtt tcgaagtgac agaggaaaaa gaatatcttg ttttatccaa tgtgcaacaa
     6301 aaagtaaaaa aattggagcc tgatatcact ttaaaaaata aagtggacgg taggctgatt
     6361 gaaataaatc cggcattaat caagaaaagt aatttaaaag acgataaaaa aaactacgaa
     6421 tggatattag aaggaatcga ttgtgcaaac tgtgctgcca aagtggaaag aggagttgct
     6481 acagttcccg gcgttacaaa cagcagcgtc aattttatga cagagacact gagcttcgag
     6541 gtagcaggtg aaaataaaac tgacgtgttg gctagtgtaa aacaaacagt aggaacttta
     6601 gaacctgacg ttgttctgcg aaaaaaatcg gacggtacat tgattgaaca tggaactgac
     6661 tctaataaaa attcgacttc taacaaatcg atttctgata aagatgagac aaaccaaaag
     6721 cagacgaata gagcttatct ggccagcctt ctcggaaata aaactaaaat tacccttatt
     6781 cgtttaatac taggattagg aatattagcg acaggaatat ttctccctat ggatggacaa
     6841 gcctctcttg ggttgttcat tctggcttat ttaatcaccg gttatgacgt tgtaggacgt
     6901 gccattagaa atattttccg aggtcaagta ttcgacgaga actttctaat gaccattgcg
     6961 acgttaagtg ccttctatat tcaagagtat cccgaagctg tagcagtcat gctattttat
     7021 caagtgggag aagtattcca agatattgct atttcaaaat ctcggcgctc cattgcggac
     7081 ctaatggata ttcgacctga ttatgccaat ttagtcacag gaaacaacgt agaaaaagtt
     7141 gctcctgaag caattaagat tggaaatatt attctcattc gtccgggcga aaaagtgcca
     7201 ttggatggaa aagtagtgga aggtgcttct gcgatggaca cttctgcttt aacaggcgaa
     7261 tccgttccaa gaagcgtgaa gccggaagac actattttga gcggatttat taataaaaac
     7321 ggattgctaa aagtagttgt agaaaagccc ttttcggagt ctactgtgaa gaaaatttta
     7381 gatttggtcc aaaatgctag tggccggaaa gcacctactg aacaattcat taccaaattt
     7441 tctcgctact atactccaat tgtggttata gctgctgcct tactggcaat tgttccgcca
     7501 ttgctagtac caggcgctac ttttaatgaa tggatatata gggccagtat ctttttagtt
     7561 atttcatgcc cttgtgcttt agtcgtttcg attccagttg gtttctttgg tgggattggt
     7621 tctgcttccc gcaaggggat tttagtaaaa gaaagcaatt tcctcgaggg tttgaacgat
     7681 cttaaatacg tggtaatgga caaaacgggt acattgacaa aagggttctg ttgcaaagtt
     7741 ttaaatctac tatcaaataa ggtagaataa tagaaaaaga tagtaggagg aatgacgatg
     7801 aatcatttta aaggaaagca atttcagcag gatgtgatta ttgtagccgt gggatactat
     7861 cttcgttata accttagcta tcgtgaagtt caagaaatct tatatgatcg tggcattaac
     7921 gtttctcata tgacgattta tcgttgggt
//
LOCUS       DASHWW010000098         7902 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.098, whole genome shotgun sequence.
ACCESSION   DASHWW010000098 DASHWW010000000
VERSION     DASHWW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.098"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(50..1390)
                     /locus_tag="U2R64_002627"
     CDS             complement(50..1390)
                     /locus_tag="U2R64_002627"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HEM8919387.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(1627..3150)
                     /locus_tag="U2R64_002628"
     CDS             complement(1627..3150)
                     /locus_tag="U2R64_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEM8919388.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(3528..4139)
                     /locus_tag="U2R64_002629"
     CDS             complement(3528..4139)
                     /locus_tag="U2R64_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8919389.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(4262..4387)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(4469..5185)
                     /locus_tag="U2R64_002630"
     CDS             complement(4469..5185)
                     /locus_tag="U2R64_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEM8919390.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(5191..5760)
                     /gene="scpB"
                     /locus_tag="U2R64_002631"
     CDS             complement(5191..5760)
                     /gene="scpB"
                     /locus_tag="U2R64_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HEM8919391.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(5744..6541)
                     /locus_tag="U2R64_002632"
     CDS             complement(5744..6541)
                     /locus_tag="U2R64_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEM8919392.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(6511..6882)
                     /locus_tag="U2R64_002633"
     CDS             complement(6511..6882)
                     /locus_tag="U2R64_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEM8919393.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(6901..7788)
                     /gene="xerD"
                     /locus_tag="U2R64_002634"
     CDS             complement(6901..7788)
                     /gene="xerD"
                     /locus_tag="U2R64_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEM8919394.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         2253 a         1718 c         1337 g         2594 t
ORIGIN      
        1 aaaagacgga atatccattt gaatatccgc cctttttgta tgtttatttt tatttagcac
       61 ataaacgata cacagcttct gcataaattt ccattgcttt atacatacta cttaattccc
      121 atcgttcatt cgcctggtgc ataaagtcag gagtatcagg gaacatcgca ccgaatgcca
      181 cacactggtt catcgtacga gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt
      241 ctccagtaat atcgcgatat gtccccaata gatttttcac taactcactg tctagtggca
      301 cgtataatga atcaaggaag tcaaattctt cataagtcaa cccatatttt tctgctgttt
      361 tagttaattt agctactaaa tcatctttct tgaatgtaac agggattctc atatctacac
      421 cgatttttgt ttgttctggt gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg
      481 attgttcatc ttctgttttg cccacgacag cttcaccagt tgcattttct tgaactaatt
      541 ttcctaagaa attgattggg ccaaaatcaa atacttctga aagagcaatt gccagacgag
      601 aaatagcatt cactccttgt gctgcatctt tcgcgtggat acttttacca agaacgacga
      661 tgccttcacc ttgttcttcg aaatcgaatt cgtgtttttt caatgcttct tttacttcag
      721 aaagcttttc tccagagtaa ggagctgcat caggaacaac attcaacgct cctccagctt
      781 ttacagaaaa ctcgttcgtt cctggtcctg tcaagtaagc ttgcaataag cctttttctg
      841 cataaattaa aggaaattca gcatctggcg caaatccttg cgtaattcct tcttcttttt
      901 cgttatattt ttctaaacaa cgccataaat tttcttcatc tgtaccaaag ataaaacgaa
      961 tacgtgtctt gaattccacg ccagcatcaa tcaaagcttt gacggcatac attgccgcaa
     1021 tagaaggacc tttgtcatct tgggatccgc gaccaactaa ccagccgtct tttatagttg
     1081 gatcgaatgg ttttgtttcc caattatttt cgtcccctgc tggaacaacg tccatatgac
     1141 acaagatacc gaataattca tctccagagc caatctctga ataaccgtaa tagccttctg
     1201 gatctttaaa tgttctaaat cctagctttt cactgatttc caatacttta tccaaagctt
     1261 caatcacttt tttaccgaag ggatgtcctt gtcctgaatc tgcttcatct agtacggaag
     1321 gaattcggat caattcgctc aatgattcta atgcttgttc atgatgttgt tctgtcacaa
     1381 attttttcat gatattatcc tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac
     1441 acaacctctt cttctcaaat aatgacgttt taagcctgct ccatcagcaa gcagaatgtt
     1501 cttaacaaat gatgaaagaa aaaacactca ctgaatggag ctattgactt gtccacgtgc
     1561 ttatcgatag ccgtttatcg gtttcttcat tcttatgata gaccttgtac ttgtatttgt
     1621 ctaggtttag aacattgctg ctacacctag gatcacacag atggctacaa ataatatcgc
     1681 aattaattta ccggtaaatt tccaccacac tgaaacatcg aaacgagcaa ttgctacagc
     1741 acccattacg atagcagatg ttggtgtaat taagtttact aaaccagatg cagattgata
     1801 agcagtgatt actaaatcct taccgacgcc ggcaaattca cccataggtc ccatgattcc
     1861 cattgttgca gcagctaagc cggaagttga aggaatcaag aatgacatag ggatatagaa
     1921 aataaatgta ataatgatga atacacttga agataatgaa cttaatcctt gttcgcccca
     1981 atgtaagatg gtgtctgtga ttaatccatt gttcataacc acttggatac cacgagcaac
     2041 agctactacg attgctacac cgatcaaatc agaagcacca gctaaaaatt cagagacaaa
     2101 ttcagactct ttcatgccat aagtgattgc tactacgatg gacattacta agaataacat
     2161 agtaatttct gggaagtacc agtcacctaa tggaagcatg cttttaccta gaaccgtacc
     2221 tagtaccgga aggtttgtta accagtttgt caatgattca aaaatcgtga aattcgcatt
     2281 caaggttgtc caaggaatca aactgatgat catgatacca aaagtaataa agaacaatac
     2341 attaacatgt ttttgttttt tcgtgattac ttcttgacga ccgattgctt caatatcgaa
     2401 atgcttcata tcttctttac gttggttgta tactaatgat tttgttggat ctttttcgat
     2461 ctttgatgca taacgataca catatacaat agaaatagct aacaaaataa cgaacatcaa
     2521 gaatcgaaga ccaatacctt cacccatcga aatcccaaca gcttgtgaag ctacgcctgt
     2581 tgcaaaagga tttaccgttg aagctagaca gcctacttga gaccctacta atacgattgc
     2641 tacagctact actgtatcaa agcctacagc catcatgact gggatcagta aagcatagaa
     2701 tggaatcgtt tcttctgcca ttccgtaagt agagccgcct aatgcaaata acagcatcaa
     2761 tactggaata agcatttttt cttttccttt gaatttcttc acaactgaag caatcccggc
     2821 atctagtgcc cctgttttgt tgataatacc taaaaatcca ccaacaacca aaatgaagaa
     2881 agagattggg attgcagcag gtgtttcttt agttagctcc cccgctggta cacctagcat
     2941 cccattgatt ggcgccatga aaatatccca cagcccttga ggattttgtt gtactcgttc
     3001 atatgatcca gcgacgatgt tgcctgcatc gtctacacta tagtgcccag ctggtataaa
     3061 ccaagtaagt acagcgatta ctgcaataat aataaataag accgtatacg ctgaaggcat
     3121 ttgaaatttt ttcttttttg tttgttccat cttcttcttc ctttcttttc cgttagagac
     3181 aacaattttg gctctaatgt tattttatca aaaagagtat cagaacaaaa ataataacac
     3241 gcattttgta aaacttttgt tcaaaaagtt cgtttttccc tattccctcc tcttttttca
     3301 ggtttttaaa gctttcttct ttttcattgt agcgtttcct tttttttata aacaaacatt
     3361 ttcgtctttt aaaaggagaa gaatttcaca tttgcaaaga attgattgat ttttatgcat
     3421 aaatcaaaaa aatactcaaa acaaacaaat aaaacgttta cattattgca tgtcttgtat
     3481 ttttttccaa aaaaaaagac caagaaattt cttgatcttt ttgatattta tttgactgct
     3541 gtatgacgtt gttcgaactg atgttgtttt cgacttaacc atggaagaag ttgcgcatgc
     3601 agcactaaaa agacagcact cacgatgaat cctttgatca agttgaaagg aacgatccca
     3661 atcagtacat agtttgctaa agacatgccc agcatctgtg ttgcgttcag ccctaaaaac
     3721 attaagtaaa gaggcgtaat aacgaaataa tttgcgatac tcataaaaat agttagagcg
     3781 atggttcctg taatgacacc taaaaatttg tttcttcctt tatgctgttt ctttacacta
     3841 aagaaataat aaatcgggaa tgtaaagatc gttgttgata agaaactagc agtgtctcct
     3901 accaaattat ccggagaaaa acctgtagtc agcagatgta atactgaacg caagaacgct
     3961 gttgcaactc cggccgctgg accgaataag aacatgctga tcaataccga gatatcacta
     4021 aaatcgatct tcaaaaaact aaaagccggc atgatcggaa aagcaaaata ctgtaaaact
     4081 aatgcgatcg cagcaaacat cgctactgca accattttct gtacacgggt gttcttcatt
     4141 tgaaatcctc ctgttaggac tcctcttcag cgaacttttt gacgtttctc tccaaatgaa
     4201 aaaactctat tttccaggga aaatagagtt agagttattt gatcaagcgt cgtcaaataa
     4261 gctctatctt ctttatccag actatactgt cggtatcgga atttcaccga ttcagctatt
     4321 tttttgcaaa ataggtcgtg gactataacc accggtcggg aatttcaccc tgcccctgaa
     4381 gacgaacctt atataatttt tgtttacata ttcattatac atatctattc aaaaaacgca
     4441 acatctaaca cttataaaaa gtaagtgttc attttgagtg gttcagcaaa ctgctgactt
     4501 cttttttgtt cagttcacgg taatccccag gacgtaggcc ttgtaaagtc agatctccgt
     4561 atttttcacg ttttagtttt tgcacaggaa gaccaactgc ttgaagcata tttttcactt
     4621 gatgattacg tccttcgtgg atcgtcaatt ccacgatact gtggtttgtc ttaggatcca
     4681 ctgataaaat ttggaattta gctggagatg tttttcgtcc ttcgatcttt attccttttg
     4741 tcaaaggtgc aagcatcgat tttgtagcga tcccttttac ctttgcaacg taaactttat
     4801 ccacttcatg ttttggatgt gtcaggcgct gagcaaaatc tccatcattt gtcagtagca
     4861 agatccccga agtatcgtaa tccagtcgac ctacaggata gatacgttct tttaccatcg
     4921 gcaaaagatc cgtaacaact tttcttcctt tgtcatctgc aacagcagaa ataactcctt
     4981 taggtttgta caataaatag taaccgtatt cttcttgata aattgggact tcatccactt
     5041 ccacagtgtc atgtttccca acttttatcc ctaattccct tacaacttgt ccgtttactt
     5101 ttacacgtcc tgcaaggatg aattcttctg cttttcgacg agaagtgatg ccagcgtggg
     5161 caattacttt ctgcaatctc tccattacaa ttattctcct ttattcattc catcaaagaa
     5221 tagatctggt gacacgtctt cttcaagtga aatttccatt tcttgtgtat caggcagttc
     5281 ttctaatgat ttcaaaccaa aataatctaa gaagtagcca gttgttccat ataatatcgg
     5341 ccgacctggt ccttctactc tacctttttc ttcaatcagt ttatgggcag ctagacgctg
     5401 taccgctcct gaaacctgaa ctcctcgaat ctgctcgatt tcagctcttg tgattggctg
     5461 tttataagcg atgattgcta aggtttcgac ggcggcttga gataatgtgt ttgatgtccc
     5521 ttgcgcatat cgcttaagta agggagccag ctctttttta gtcgttaata cataatggct
     5581 ttccgtttca aaaatatgca aagctgagtg cgagttttga gtgtaagatt cttttaattc
     5641 tttcactaaa cttgtgactt ctgcttcgct gagatttaac agtccgctta attcttcatt
     5701 actgatccct tcctcgccaa caataaaaag aagggcttca agttcactta atttcgtcat
     5761 gttcggtatc tcctactgct ggataaagca taattgattc atagttttct ttttgttgcg
     5821 caatgatctg cccttttttc atcaattcta gcaaagccat aaaagtagtg acaacttcac
     5881 ttttagaagg tgactcaaaa aaagaatcga aagtacagcc atgcgcattt ctttttatac
     5941 gctcttcgat aaataccatt cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt
     6001 ccactttttg agaaaatttc ttacgttcta agattttctg catggcacgg atcaaatcga
     6061 tttttttgac ttgtcctcgc ttcaacggct tttcagcatc cgctaaccca tcgatgttca
     6121 taggttcttt tgtgtaataa agacttcgtt cctctgcttt ttctgtcagt ctttcagctg
     6181 catatttata tttacggtat tctaaaagct gagtgaccaa ttcttctcga ggatcttctt
     6241 cccataattc ttcatcgtct gtgccgaatt cttggacagg aagcaatgtc ttgcttttga
     6301 ttgccatcaa tgtagcagcc atcactaagt attctcctgc aacagctagc tcgagtgttt
     6361 tcattgtatg gatataattc atatattgct ccgtgatcgt agcgatcggt atatcatata
     6421 tatcgatttc catttgctga atcagatgaa gcagcagatc gagaggaccc tcgaatacat
     6481 ctaatttaat attgatctcc gtcaactcat tcactctttc ttctttttct ttgctagcca
     6541 ttttccaatg taaggctctg tgatttcagt tgcacggatg gagacatccg ggtacttttc
     6601 ctgtaattca tctaacattt gaaagcccat attctcaccg cgataagacg gattcaaaga
     6661 aatgtcatgg atgatcagct gatcgttcgt tgcccagtaa ataccaataa tcccttgaat
     6721 gttggttgaa ccttctggcg taaagaaaaa aagttcataa tcgtcttcag attcgtacgt
     6781 atcaatctcc ttcaacaaag aagttttacc tgtcagtttc ttatggaaac tcaatagtcc
     6841 catagcaatt ttacggtttt ctttccggta atgtgttaac atcttctcac cttcctatga
     6901 ctaagccctt ggaaaatgct gcttataaac atccgtcatt cttttcttcg tgatatgtgt
     6961 ataaatctga gtcgtagaga tatccgcgtg acctaacaat tcctgtactg tccgcaaatc
     7021 agctccattt tctagcagat gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc
     7081 tttgtaaatc ccagcctctc gtactaactg cttcagattt ttccagattc cttgccgaga
     7141 aagacctttc ccatgattat tgacaaatac atgcatttca gatgcgtcct ttacaagtaa
     7201 tggacgtgct tcgtctaagt agcgttccag ccattggatc gcataatcac ctaaaggaat
     7261 gatccgctct ttatctcctt ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc
     7321 tcccaatttc aatccaatca attcactgac gcgcatccca gtagcataca tgacttccaa
     7381 gattgcacga tctcttatcc ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc
     7441 tacttctgtc agagtcaatg tacttggtaa tttctgtgct ttcttcggcg tatcgatatg
     7501 ttgcatcgga tcatgatcag tgatacgctc ttgccgtaaa aactgatgga atcttctgag
     7561 acttgagatc atccgagtaa cagttgctgt cgcttttttt tcttcatgca acttctccag
     7621 aaaacggatg actaaaaagc gatcgacatc ctgccatgaa gcaattttct gctcctgtag
     7681 aaaatgcaag tactgttcca aatcacgttc atagctttgt cgtgtattgg cggacaatcc
     7741 ccgttcaata ttcaagtagt ggagataatc gttgatttgc tctttcataa taatccccct
     7801 catgcctctc tatcatatca gataccgctt cattctgata gtctttttcc ataatctgag
     7861 caaagaaaaa gccgtctaga cactcagacg gactggtttc tt
//
LOCUS       DASHWW010000099         7824 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.099, whole genome shotgun sequence.
ACCESSION   DASHWW010000099 DASHWW010000000
VERSION     DASHWW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.099"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1182)
                     /locus_tag="U2R64_002635"
     CDS             complement(<1..1182)
                     /locus_tag="U2R64_002635"
                     /inference="COORDINATES: protein motif:HMM:NF033550.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8919395.1"
                     /translation="MSMNHFIKQLFTIKDSNIQIQSFEETFYKSRKSIVIEGTLIRTY
                     RRCPCCKDSTKQIVKNGKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLV
                     TPFCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPR
                     CLLFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHY
                     IVTDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQ
                     YRQLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQ
                     DLLTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLEN
                     LH"
     gene            complement(1361..2134)
                     /locus_tag="U2R64_002636"
                     /pseudo
     CDS             complement(1361..2134)
                     /locus_tag="U2R64_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            2155..3357
                     /locus_tag="U2R64_002637"
     CDS             2155..3357
                     /locus_tag="U2R64_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HEM8919396.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            4090..5058
                     /locus_tag="U2R64_002638"
     CDS             4090..5058
                     /locus_tag="U2R64_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8919397.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            5069..5884
                     /locus_tag="U2R64_002639"
     CDS             5069..5884
                     /locus_tag="U2R64_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HEM8919398.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            5952..6662
                     /locus_tag="U2R64_002640"
     CDS             5952..6662
                     /locus_tag="U2R64_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8919399.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            6698..>7824
                     /locus_tag="U2R64_002641"
     CDS             6698..>7824
                     /locus_tag="U2R64_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HEM8919400.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINYFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         2599 a         1235 c         1589 g         2401 t
ORIGIN      
        1 atggagattt tccagtcgtg cattcgaata cttcttcagt aatgccagcc gaatcccttt
       61 ctcgtatttg aaaaaggctt ttttgatatg gtgcagttcc aatggaactt ctccaggcat
      121 tgctcgaagc agctggaaaa aagtatctgg atctttttcc tgatacgcag taagcaggtc
      181 ttggtagtaa cgataagctg ttttaagttc aggagaaatc tttagaaggc ggtcaactac
      241 ttctgtttca gtcaatagtc tccaattgaa attgcgtctt ttcgttagtg tattgtaatc
      301 taaacgatcc tctgatttta aaagtaattt gaataaggat ttcaattggc gatactgttt
      361 agcttgtatt gggtcttttt gatcaagtgt tttcatcaca cgttttcgaa ccgcatcgaa
      421 gaagcggttc agatgttgaa caatgtgaaa ccgatcgacg atcacttgtg catttggaaa
      481 acactcttta actagtgaga aataaggagc gttcatatcc gttacgatgt aatgtacacc
      541 caacctcgct ttgagagaaa aacgcatgaa aaaagcaacg agatcttttt tacggcggct
      601 aggtaagatc tcaaacagtt tcccggtctc accgtccata caagaaaaag aaaatttacc
      661 gtgccatgta gaaagagaac gaaactcatc gaataataga caccgaggta aatactcaag
      721 attctgacgg atatctgatg acaaggcgga caatgtccgc tgaacagttg tcacagaaac
      781 atcgcaatgt ttaccaattg cttttataga ttgacgctct gtcaattctt ctaagatctt
      841 gtaatgaatc tgcttagaaa taaagcagaa tggggtaacg agatacgtcc gagcggtaaa
      901 atatttttta catgctcggc agaggtatcg ctgtttcttc aaccgaagat aggtccgttt
      961 attaccgcta cgattcagga gaatcataga gatcttcttg ccatttttaa cgatttgctt
     1021 tgtagaatct ttacaacacg gacaacgtct gtaggtacgg atcagagttc cctcaataac
     1081 gatacttttt ctgcttttat aaaaagtttc ttcaaaggat tgaatttgga tatttgagtc
     1141 tttaatagta aagagttgtt tgataaaatg attcatggac atacaagaat tcccccagaa
     1201 tgatgttgta ggagactcta ttctaccgga aattttgtat gtctttttgt ttttttacaa
     1261 aaaaactagg acagatagaa aatttccatc agtcctagaa attatagagc caataaaact
     1321 tagtccgata tgcggcgcgt tctgtgcgcc gcatattttt ttagttttca aagatcagac
     1381 cttgttgtaa atagatccgt gcccgaaagt tataaaagtt gcgataacca aacgcaattc
     1441 gtttaatcag cttgatcttg ttatacagcc cctcagtgac gccgtttgag tgggacacct
     1501 taaaggcatt tgaaataccc gattggtagc gatggaagat cgtgaatttc tttttaaacg
     1561 actgaggtaa cgtagatgaa attgttttaa gggtttcttg aaagcctacc gtatctcgtt
     1621 taacgaaata atagcgtaat aattgacaaa aatgatacgc agttcgcaat tcttcgttgt
     1681 agcttaacag ctcattaacg atttctgttt gactaattgg tcgtttaaac agtcgatgat
     1741 aatgccgttt gagtgcctcc catgtcgtgg aatctttgag taagagtttc caatatcgct
     1801 tgagccgacg gtacttcttc tgattttcag agtgtgaggt tcgaaaacga ttcatgatct
     1861 ggacacgtaa ttgattgaag ctgcgattga tgtgttggac aatatgaaag cggtcagtta
     1921 cgatctccgc atttggaaag accgttttaa gcaactgaca atagctggca ttcatgtcca
     1981 tcactaggta cttgaccttt aaacgggcct ttctaggaaa gcgcaggaag tattgagtta
     2041 gtttgtaaag tctgcgatct tcaagggtcg taaatagctg attggttgtc ccatcaacac
     2101 aaataaaact catggaacca gaagtggcaa cattgtgtac ttttctttgc aatcttgtgt
     2161 acaaaactat tgcaaaacac agcgcataag aatccttaca aaacagtaga tgaagcaacc
     2221 caattagatc ttgttatagt tgttaatcag ctcttaacgg gttacgattc aaaatgggtc
     2281 aacaccctat acttagataa gtcacttgaa tatcagaaca taattcaggc tttttcacgc
     2341 acaaatcgtc ttaatggtcc tgaaaaaccg ttcggaacca ttcgttatta tcgtaaagca
     2401 catacgatgg aacagaacat tgaagaggct attgagttat actcaggcaa acaagcaaaa
     2461 gggttatttg ttgaaaaatt atataataac ttagaaaagt tgaacgatat attcgaagaa
     2521 attaagtccg tatttaatat ttctggcata gaaaacttca gtcatttacc ggaggttcca
     2581 ggggaaatta agcaatttgt aaatctttat aatcaactaa tccattgtta tgaatcagcg
     2641 atgatacagg gattcacatg ggcaaaatcg acttatgaaa tccaggatta tgaacctata
     2701 acagtagtaa tcacagaata tgaatttaat atcttggcac aacgttacag cgagatagag
     2761 agagaaccta gagacggaaa tgatagtata gcgtatgaca ttgattacca attacctgaa
     2821 ggtagtcgta gtcgtattaa ttatgagtat ttaaacacaa acttcaaaaa atacatgaat
     2881 ataaaagaag aacgtgattc gaatttaatt caatcattgt taaacgactt acatcgcaca
     2941 tttgcgcaat taccagtgga gttacagcca tatgctgaga tgattctaaa tgatgtaaat
     3001 aatggggaat tagttatcaa agaaggatgg gaatttactg attacctcaa tgaatatcag
     3061 cttagtgaag aggacgattt tatccaagat ttagtggatt caaccaatat taatgaggca
     3121 ttattacgtg agatgttgga tttacgctta accgaggtaa acattaatga atatagtcga
     3181 tttgataaat taaaatcaag tgttaacgta ggtcatttca gtggatatat cgagaaaaat
     3241 ttaggtaaaa tggtaatacc aatcaaggta aatatgctaa ttgacagatt attgcgtgca
     3301 tttttattag aagatgtatt cgatgttaca gagtacataa agaattactt taactagagt
     3361 acacctacat cttatagtac ataaaaaaat tcatcttttt tagtttaata attcaccaaa
     3421 aaggtgagta atgccatttt tgaaaattga gcttgtttta tgtctacatc tgtatccgta
     3481 tataatccaa aggattataa actcagaaga gtctttattt tttctgaata taactactgt
     3541 atcaaaaaca atcgattatg agacaaaaca aaatgacctc ttttatttaa gaaaggaggt
     3601 cattttttgt atcataaatt gtattaaaat caatgtatca ctttttaatc aattttaaga
     3661 ccataaattg cgtactaaaa gaaattctgc aattcaaaat aaagcatttt aagccatttt
     3721 caaatttaag tgcacccatc tacccgtcaa atcactttat tttccactcc agtagtttcc
     3781 taattcaact gtgtgcaaaa cgatttcttc taaacaaatc aagacaaact tataaacctt
     3841 catcccagca ccataattat ttaaatcata ggcatttttc gaaattagta tatgtactca
     3901 agtttcactg cagattattt atatttttta gagaaataaa tttttcctat tgacaaacac
     3961 aaagaaagcg gatacaatac aattatgtca catgacgtta tatgacgtta tgtaatatct
     4021 ttacatttaa tcagttactt ttattttgga taaaattaac atttttaaaa ttttaaggag
     4081 gaaatgttga tggatgtagc aaaaacggtt aacgcaattg tagaaaaaaa tgatggagag
     4141 atttctggaa tttatttggt ggcttgtggc ggttcgctgg tagatatgta tgtctcagat
     4201 tattttctta aagccgaagc atcgaagtgt attacaggct tatatacagc gaacgaattt
     4261 aaccatgtaa ccccaaagca attagatgat aaatctgttg tcattctatg ttctcatgga
     4321 ggaaatacag cagaaacggt aaaagcagga gaagtcgctc aagctagagg agctgtgact
     4381 gttggtctga ctcataataa aactgcggat ttattaaagg tttctgatca tagtttcctt
     4441 tacgaatggg gagatgatgc aaaaatagtc aataatccta tggccatcat tcttgattta
     4501 actgtatctt tggtcaatgt taccgaaaca tttgaacatt acggtaaatt cagagaaggc
     4561 atgaaggtta tcgataccgt aattgaaaat ggcattaagc aggtgcagga tcgtattaaa
     4621 gtgtttgctg ataagtacaa agatgaaaca atgttttata tcttaggtag tggaccatca
     4681 tatggacatg cttatggttt ttcaatttgc tctttgatgg aaatgcaatg gcttgattca
     4741 acttctgttc attctggaga attcttccat ggaccttttg aagtaacaga caaagatacg
     4801 aattttattc tcttgatgag cattggacgc actcgtgctt tagatgaacg ggcaaaacga
     4861 ttccttgata aatatgcaga aagagtagaa atcgttgatg caaaggaact aggattggat
     4921 atgatatcag atgaagtttc tgaattcttc aatcccattt tattctacag tattctttca
     4981 gaatatcgtt cagctttagc agatgcacgc aatcatgatt tagatgttcg tcgctatatg
     5041 gggaaagtgg agtactagga ggattaaaat gaaggtatta ggcttaggtg ataacgtcgt
     5101 cgataaatat gaaaatctgg gaattatgta tcctggagga aattcattga attttgcagt
     5161 ttttgcaaaa aaactgggac atgaaagtag ctttatggga gtttttggct cagatgagga
     5221 ggcagctcat gttttatcag caataaaaaa aataggactg gacaacagtc actctcgctt
     5281 tgaaaaaggc gagaatggct gtgccagagt gaagattgat gagggcgacc ggattttcct
     5341 tggcagcaat tcgggaggtg ttactcgtga atacccgatt cagcttactg aagaagacag
     5401 agaatattta aaccagtttg aattgattca tatgggatta tatagccatg tcaatcatct
     5461 attagaagag ttacaaaatg tttctggaaa gatttcttat gatttttctg acgactttac
     5521 ggaagaagag gttcagcggg caattgataa agttgatttt ggcttctttt ctatagaaga
     5581 cttttccgat gaagaagtaa agcagttttt gatgaagcat ttttgtgagc gaaatgatgt
     5641 attgattgca acccgaggag aaaaaacggc tattggttat gatggagcaa agttttatga
     5701 agtgaacccc gtgctagaag aaccagttga tacaatggca gcgggagatt ctttcttaac
     5761 agctttccta ctttattttc tcgaagggga cgatatagtc accgcgatga aaaaggggaa
     5821 tgaatttgct gggaagtctt gtctggttga cggttcgttc ggctttggta ttcattacga
     5881 ttgagcttgt tttaaattcc tgcatttgat aacctaaaga aagaaatccc ggtaaagtgg
     5941 aggttaaaaa aatgctggat acaaatgcac aattaccatt gtacttacaa ttaaaagaaa
     6001 tattaaaaaa taaaatcaat acaggggagt atcccgagaa tacgaaaatt cccgctgaat
     6061 cagagctgat agaaagttat gaggtcagcc gaatcacagt gagaaaagca gtagaagaac
     6121 tggtagaaga agggtaccta cttaaaaaac aagggaaagg aacttttgtc aaccggcata
     6181 aagtttttcg taaaattgaa tatgttatgg gtttcagtga gagttgtaaa tctaatggtt
     6241 ttacaccgac tagcattgtt ttggaacgca agatcattcc agcaactgaa gggatggcaa
     6301 aaaaactcga tatcgctcaa ggtgatgatg ttttatatat ccagagaaag cgaatggcgg
     6361 ataacatccc cattatgtta gaaaacaatt atttttctta tgaaagatat agtttcttaa
     6421 tggaggaaga gctgactgat tctttgtatg aagtacttaa agtccaaggt accttagcca
     6481 tcaatcctgg ggaaactgca cttgaaattg tcacagctga tgaccaaatt gccaaaataa
     6541 tggaagtagc tgttgggacg ccctttttct ttatggatac tttaatcaac gatcaaaaca
     6601 acataccaat tcatgtaggt aatcaatatt acctgggaga agtatatcgt ttttacttat
     6661 gatttcctgt tttgatttca aggagtagat tttatttatg aagcaaatat tgcggtcaaa
     6721 aatgattttt gatggagagc agccaccttt caaaggttat attgtaatca atgaagggat
     6781 cattgaaaag gtggaaaaca actggaatta cagtgatcta ttaaatgaaa acacggaatt
     6841 aattgcttat gatgatcaat tcgttatgcc agcaattcat gataatcatg tatttttcag
     6901 tggttatttg gctatgaatg ctggcataga tttaagcgat acatcttcag ctaacgaggc
     6961 tgtagagcgt attaaagctg taatgaacca taaaaaagca gatgaaccaa tttatgctca
     7021 tggctgggat gctgccctgt ggaaaactga cccatcagaa gagctattga atgaaataaa
     7081 ctactttggt ccaatcacag cgatcgacaa aaatcgcagc cattgttgga tgaatgctat
     7141 tgctaagcag acttatggtt ttacagaaaa agaaaccagt gctgaaagtc gagtattatt
     7201 aattaaggaa atgctagcaa acaaaaagct tttagcagag gtttacgctg aatttgaagc
     7261 attactgctt tcaaaaggtg ttatatcaat gaaagaaatc gtttttgatg acgcagaatt
     7321 tctttctaat atacctcaga ggaaaatact tagtaaccta tatgtgcagg cagtccaaga
     7381 acctctacag catgaacttc tatatgagta taaggaaaaa gttttccctg aaaaggtccg
     7441 ctttggtgga gtgaagatca tggtagatgg tgttgttgcg gatagaagtg gagatattta
     7501 cggtgtttat cagtcaggag tagcttcacc cgagattgac tatgaggcaa ttaaagcaga
     7561 agttgctgca ttcaatgaag tagagattcc ttgctgtttg acaacggaag gagataaagc
     7621 gggttataaa gctgcgtcaa ttcttgtcga atttggaaag cggttacctg aaggcgtttt
     7681 taattcgatt agtgatttgg aaatggttac tcaaaagaca gcagaaaaaa tgaacgaagg
     7741 acaagtagta gcagaggtat atccacaaat tctcggcttg aatcaaacgt tagaagaggc
     7801 ttacatgtca actgttataa aaaa
//
LOCUS       DASHWW010000100         7783 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.100, whole genome shotgun sequence.
ACCESSION   DASHWW010000100 DASHWW010000000
VERSION     DASHWW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.100"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(619..1704)
                     /locus_tag="U2R64_002642"
     CDS             complement(619..1704)
                     /locus_tag="U2R64_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEM8919401.1"
                     /translation="MSTEIQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSQTIDKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHNAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            complement(2024..2431)
                     /locus_tag="U2R64_002643"
     CDS             complement(2024..2431)
                     /locus_tag="U2R64_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919402.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     KNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            complement(2450..3268)
                     /locus_tag="U2R64_002644"
     CDS             complement(2450..3268)
                     /locus_tag="U2R64_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8919403.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            complement(3494..3787)
                     /locus_tag="U2R64_002645"
     CDS             complement(3494..3787)
                     /locus_tag="U2R64_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEM8919404.1"
                     /translation="MSINTFVYSHPINVYIIKYLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSMNMTDVYEKLLILENEYDQFTSNQQRKVKKQID"
     gene            complement(3923..4102)
                     /locus_tag="U2R64_002646"
     CDS             complement(3923..4102)
                     /locus_tag="U2R64_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919405.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLFI"
     gene            complement(4099..4449)
                     /locus_tag="U2R64_002647"
     CDS             complement(4099..4449)
                     /locus_tag="U2R64_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919406.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRANQNLAKEQMRTE
                     EIAEILNASVIKNRSVCIQKEERNAEGYYPDDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4442..5767)
                     /locus_tag="U2R64_002648"
     CDS             complement(4442..5767)
                     /locus_tag="U2R64_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEM8919407.1"
                     /translation="MLDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKNLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYQNVPDKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIKDLANWNPYTIKSRLGVIGLQLYFHANGIDRTDIAIAPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHHCKTGCVHLHIGTSILETRPGFSHQMKI
                     SITDNTRELQDYCLFLFNKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDDEK
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            complement(5876..6079)
                     /locus_tag="U2R64_002649"
     CDS             complement(5876..6079)
                     /locus_tag="U2R64_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEM8919408.1"
                     /translation="MKEQQLGYTLWGRPLYGLERRTAVSIDCACGELIQLNIQTKQYN
                     CKNCGNCYQFIDQDFQLLNEKNK"
     gene            complement(6239..6814)
                     /locus_tag="U2R64_002650"
     CDS             complement(6239..6814)
                     /locus_tag="U2R64_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919409.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKLFAKKNNPNFKEGRPKATITPKKRHAYELI
                     TSGKSYKEVEAITGFSRSTLFRIKKQIEASE"
     gene            complement(6830..7435)
                     /locus_tag="U2R64_002651"
     CDS             complement(6830..7435)
                     /locus_tag="U2R64_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEM8919410.1"
                     /translation="MILENKLGLTNQVELAKAEEKLSKQKAKELYDSGKINEIEVGTF
                     KGLSEIHDFLFSEIYDFAGKIRTVNIAKGNFRFAPVMYLEQSLNHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT         2301 a         1430 c         1151 g         2901 t
ORIGIN      
        1 tttaacctta acacagccaa aaaaagtggt atcacttttg aatatctgtt atactaaatc
       61 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggagtgagct taatgctttc
      121 ctgtagggca ctgacggaga ttaccagtct cccgagtctt acaggggcct ttcttttttt
      181 tgtattttca attgtccaaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      241 aagcatagca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      301 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      361 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      421 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgacattaa aacctacgtt
      481 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataataacta tttatttgta
      541 acatttgtaa taaaattaaa attataaaaa agttctaatt taaaattgat catttttata
      601 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      661 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcaa taaaccagtt
      721 ttttacatac acaaaaatca aattctgcaa attatttact ttctcagtct tttgtttttg
      781 ataagctttc agcaacgtca tatataatcc tttatccgca tcaattccgt aagattcaag
      841 ttcttcatac acaactaccg tcttctcaag ttcctcggct ttatgttttg cgttgtgtat
      901 tgtggtgacg gtttgttggg cttcttcgta agtgttagaa aatgttttta tcaagcttaa
      961 taccttttct ggtacaaatg tgtttatgct gtcttctttc atgatttcaa cgaagttatc
     1021 tagcaaaact tgattttgta attggtctgt ttcagtgtct tttaagtgtc ttttagtgtc
     1081 taaagattta ttaatataat aatcttgtgc gatttccgca tttccagtgt tatcaagggt
     1141 ttcagctgtt ttttctcgac gtgcgatttc cgcatttcca gtattatcaa gggttttagc
     1201 agtttcctct cgacgtgcga tttccgcatt ccgagaagag gttgatttat caatagtttg
     1261 gcttaaatcg tcatcgaaag aattctgaat aaaaagatca tcggcactta tttcaggttg
     1321 aagtaaatag tatttatttt tttcattttt tttcgttttt gggttaaatt ctccttttac
     1381 gactgaaatc aaattatatg tttctaactc gtttaaaatg gtttttactt tgccttggta
     1441 gcaatttaat ttgtccatta ggtctgcttg tgtaaattcc aaatataata gaccatcatc
     1501 gtcgatccat ttttcatgta aggctctacg aaattcattt ttaaaaagca tataggctat
     1561 ttttgagctg tctttcattt tagagtattt agaattctga attaaaaaac taggaaattt
     1621 ataatatttt tcaatataaa cattcgttgc tttatatccc caatttttaa taatcatttt
     1681 ttgagattga atttctgtag acattaaatt tctccttctt catagaaact tgtatatatt
     1741 cacgattttc aacaagtgaa ctataccatg tattaagggt gaataaaaca ctttcagtat
     1801 ttaaggtata agttatatat taaaaaaata agtataagtt atactttaaa tacaaataat
     1861 gtataactta tactttaaat aataatttta taatgttgat ttaatcgcaa atttacacgt
     1921 tgtttattaa gttatacttt aaatatttaa tgtataactt atactttaat attcatttat
     1981 ctagtataac ttatacttta attgaatacc gcatgaaaaa aaattatttt ggtaattttt
     2041 caaactcttc ttgtatttct tctcttatgt gttcttcttt tgctactcct agtctatgct
     2101 ggatatatga gtctgctaat gtattaacaa ttttttcgaa agaaattctc cctttttcac
     2161 tttgtaactc cgtcatatag tcttgtaaaa ttgagagttt gctatttaat gccggagaga
     2221 tctttttagg aactgatacc ttgtttcttt tatcaggaat tgaaactggt cggcctcttt
     2281 ttttcaatgt aatatttttt gtgttactca atgcactatt gctaaagtta tattcaccgc
     2341 ttattttcac atcttggcgt ttgttattgg gtaataatgg ctcaaattcg ccattctcca
     2401 tcattttagg aatatcaaaa tctttaggca ttacttatgc aactccttat tatttattta
     2461 aaaactcttg tctagcatct agttctgcca aaatatttat aaatacttgg tgtgctttat
     2521 aatcccattg atcaaaattt ccatttttgt attttcttaa atgtatacca attttagaat
     2581 accttctcaa tcttttttga taatgaatga gatttttgga taccacggtt ccgtattttt
     2641 caattgcttc ttctaggatt tcttcatcaa aatcatcatt tggttctacc atacaaggta
     2701 caatatctat aatttgcaaa tcaagatcgt atctatcgac catgaatttt tgataattta
     2761 catatttgtt gactccctct aaggattctt cagctgtttg aaatgaaatt atcgaatagt
     2821 ctgaagctgc catagcatta tcggaaaatt cgctaatggt tggtggtaca tcaataaata
     2881 tttcttgata attgttcttt attggaagaa gtaatttttt caagacagta acttggtcta
     2941 attcattttc atgtttatta gcaaaagcgg agaatgatcg aaaactagtg tcacatgcca
     3001 gaaggtcaag attttcattt accttaataa tactacttgc taattctcca tttgcgacac
     3061 catttgttat agtggttttg atatcggtta taccgaaagt tcttgctatg acttgtgtta
     3121 agttcgcttg agggtctaaa tcaataataa gcgtttttct atttcttatc attgcattgt
     3181 cataagcaag catgctgact atcttagttt tacctactcc tcctttaaaa ttgccaactg
     3241 taaatgtagt cccttgaaaa gtatccatgt aaatcctccc aatctttaat tgataattaa
     3301 agtataactt atatatcgga aatggtcaac attaaaagta taacttaaat aataatatct
     3361 aaaaacgttt ggatatagcg gtttttaaga ataaaagtat aagttatacc ctaaatatat
     3421 atggtataac ttatacttta attatttaag gtataactta taccttagat attgcttttc
     3481 gaaaatagct attctagtct atctgtttct ttacttttcg ctgctgattt gaagtgaatt
     3541 gatcatattc attttctagt attaataact tttcgtatac atcggtcata ttcatactag
     3601 aagcaagact tagatcatat acaaatgaag caggtaatga ttttattcta cgttgtcggg
     3661 ttatccagct tgcaaccgtt ccttgtgggt aggcatataa ctcacaaaat tgttctacag
     3721 tgattcctaa atatttgata atgtaaacat tgatcgggtg cgagtaaaca aatgtattga
     3781 tggacatggt gcgtaagcct actttctttt attattgcgt ttgcaataat agtttaacac
     3841 acgcattatt ctagtatcta ctcctatttg taaaaacaaa aaaggattca tagagataac
     3901 tctatagaat ccgtaaaata ccttatataa ataacgggaa aatataaaac ctaaaattat
     3961 gataacctgc tgcagcttct acatagaaag agaaacgctc aacaccaacc tcatttatca
     4021 aacgttggcc atacccccaa atctcttctg atagctgatc aaaggttata tactttagct
     4081 catattgctg gataatgttc attctaatcg actccattta ttatcctggt aaaattcgat
     4141 atgacgtatt tcgtcgtagt gaattttgtc tttgccaacg tagattccca gctcatcact
     4201 acctaagatc tttccaacaa tatcgtctgg atagtatcct tcagcgtttc gttcttcttt
     4261 ttgaatacat actgatctat tttttatgac tgaagcgttc aatatttccg caatctcttc
     4321 agtcctcatt tgttcctttg ctaaattttg atttgcacgt tgctcattat ctgcatcgat
     4381 ctcttcagta tgatccgata aatagaaacc tgcccatttc aatcgtcctc gatcgttata
     4441 gtcaatcatt tttaagcccc cctgcgccgc ctgcatggcc accaaccaac gtgcttctag
     4501 taatactacg agcgccttct aacatcgaag aagcatgtac aattgacgta aaaccatact
     4561 tctgcctaat tttatctatt attttgtcta gtttttcgtc atcaatctgt ttttgtggat
     4621 cactaaacaa atccagctga agcgaatcag tataaactag cttgctgtaa gtgattccga
     4681 catggcggac ttcttgtccc tcatagtatt tattaaataa gaacagacaa tagtcttgta
     4741 gctctcttgt attatctgtg atagatatct tcatctggtg tgaaaaccct ggtctcgttt
     4801 ctaaaatcga cgttccaatg tgtaaatgaa cacaacctgt tttacagtgg tgttgcctaa
     4861 tacggattgc tacttgctca gccatttctt ttacgaccag ttcgatttca tttcttctag
     4921 tataatctcg tggtagcact tgtgaattgc catatgattt ttcctttgtc ggttctggtg
     4981 cgattgctat gtcagttcga tcaataccat ttgcatggaa gtacagctgt aacccaatca
     5041 cacctaaacg gctcttaatg gtgtatggat tccaattagc taaatctttg atactcatga
     5101 tccccatttg gttgagcctt tttttcattc gagaaccaat accccaaaag tctgtcattt
     5161 caggaatatt ccatacttta tcaggaacat tttgatacgt ccattcggca ataaatcctt
     5221 cattatgctt cgcttcattg tctaaggcta gtttagccaa aagaggatta tcgccaacac
     5281 ctactgtagc aatcaatcct agctcttctt taatacgttc ttggatcatt tgagcgagat
     5341 tcttccttcg ctgacttcgt gttccttcag tcgtaaaaag attcagtgat cgggtcactt
     5401 ttaagattga ttcatcgatc gagtaaatca gtagatcttc atcagccaca tatcttctga
     5461 aaatattatt tacctgcata ttacgcttaa tataaaggtt catacgtggt ggaacaacat
     5521 gtaatgtttt agggaaaggc tgtggtagat cccgtggtct gctgacatta gaaataccat
     5581 atttcttctt tgcagctggt gaagaagcta aaatcaaccc tgatcctgta ttatccgctc
     5641 gactcatgac aactaattca gtcgttaatg gatctaaatt tctttctata cattcgacac
     5701 ttgcgtaaaa acttttcata tcgattagaa agtagtcatt gactggctct tttgagtaat
     5761 caagcataaa gttctccccc tcttctctca tattatacaa acatacgttc gtgtttgcaa
     5821 cgaggatctt ctctaaatag aaaaatagcc agacaattgt ctgactataa taaacctatt
     5881 tgtttttttc gtttagcaat tggaagtctt gatcaatgaa ttggtaacaa ttcccacaat
     5941 ttttacaatt gtattgtttc gtttgaatat tgagttgaat caactcacca caagcacagt
     6001 caatcgatac agccgttctt cgttctaatc cgtataatgg acgtccccaa agagtgtagc
     6061 ctaattgttg ttctttcatt tacttcgttc ctccctaaaa atatgtctat tcgtagctgg
     6121 tatgacgctt cgttcgacca atgatacatc ttaatgagtg aacctgacct tagaatgctc
     6181 gtataaacaa cgatttattt gatttaaaag agatttttat attaatttta tcaatcttct
     6241 actcactcgc ttctatttgt ttcttaattc taaaaagtgt actacgactg aaacccgtta
     6301 tggcttccac ttctttatac gatttgccgg aagtaatcaa ttcatatgca tgcctcttct
     6361 ttggtgtgat tgttgctttc ggacgtccct ctttaaaatt aggattattc tttttcgcaa
     6421 ataatttccc ttcctgagta cgttctacaa tcatatcacg ttccatttca gctacactca
     6481 acaacgtacg tgtaaccatt cgacccatcg atgtattttc gatcgtccct agattcaata
     6541 ccttaatcgt gacgttatca tcgagtaaag gttcaatgat ctctagtgct tctcttgtat
     6601 tacgggcgaa tcgatcaagt ttcgtaacaa cgatttcgtc tccaggcttc agaccagcca
     6661 acagctgatt aaactttggc cgatctcgtt tcgtacctgt aaatttttca gaaaaaatat
     6721 tcttcttctc aacaccgttc tcaagtagct gttgtatctg ttcctttgta ctttgagaag
     6781 cggttgagac acgtgcatag ccatattttg tcatttaact cacctgcttt tacaaatcat
     6841 ctatcgtata ctcagagtat ccttcataga agtagctgac atcgattcct ttcatatata
     6901 actcacgatc gtcaatttta tcagtcaggg cattggaaat gagatagcgt atttccaagt
     6961 catttattgg actgcgctcc attgcagaaa gatagtctgc tttatcgatc aagttccaat
     7021 cgaccacttt ttgcaattct tcctttaaaa tgagatccag ccaaattcta gtactgcgcc
     7081 cgtttccttc gcgaaaaggg tgagcgatat tcatttccac gtatttctta ataatctctt
     7141 cgaaagaagt ttgcggcatc tgatcaatat gatttaaaga ttgttctagg tacatgaccg
     7201 gcgcaaaacg aaaatttcct tttgcaatat taactgtccg aatttttcct gcaaaatcat
     7261 aaatttctga aaagagaaaa tcatgaattt cagacaagcc tttaaacgtg ccgacttcga
     7321 tttcatttat ttttccagaa tcatataatt cttttgcttt ttgcttactg agtttttctt
     7381 cagccttggc caactcaacc tgattcgtta aacccaattt attttctaaa atcatggaaa
     7441 atccccttaa ctttttgaca taagtttatg aaacactaca aatcctattg tatcgcgaat
     7501 ttaaccatgt gtcaaaaact attaagtttt tgacacgtag ttagttttca atagaagcca
     7561 tctgtccttt tctttttaaa tggcaaaaat tttttatttt attcggcaca aactataaac
     7621 atttaatcgc taagaaaatc actcaattat tttgagtgat tttttcagtt cttattttaa
     7681 aacaaagtgt tcataaaatc aggtgtttct ttatttttca gtagcatacc ctgtttttat
     7741 tttgagtatt agtaataatt aaaaaaacca cttgtaattt tat
//
LOCUS       DASHWW010000101         7699 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.102, whole genome shotgun sequence.
ACCESSION   DASHWW010000101 DASHWW010000000
VERSION     DASHWW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.102"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            544..1107
                     /locus_tag="U2R64_002652"
     CDS             544..1107
                     /locus_tag="U2R64_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919411.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="U2R64_002653"
     CDS             complement(1386..1673)
                     /locus_tag="U2R64_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8919412.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="U2R64_002654"
     CDS             complement(1663..1992)
                     /locus_tag="U2R64_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8919413.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="U2R64_002655"
     CDS             2297..2626
                     /locus_tag="U2R64_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8919414.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="U2R64_002656"
     CDS             complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="U2R64_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEM8919415.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="U2R64_002657"
     CDS             complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="U2R64_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEM8919416.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="U2R64_002658"
     CDS             complement(4890..5498)
                     /locus_tag="U2R64_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEM8919417.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="U2R64_002659"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="U2R64_002659"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEM8919418.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="U2R64_002660"
     CDS             complement(6528..7496)
                     /locus_tag="U2R64_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEM8919419.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2352 a         1532 c         1280 g         2535 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ataggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tagttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatt
//
LOCUS       DASHWW010000102         7599 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.104, whole genome shotgun sequence.
ACCESSION   DASHWW010000102 DASHWW010000000
VERSION     DASHWW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.104"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(943..1356)
                     /locus_tag="U2R64_002661"
     CDS             complement(943..1356)
                     /locus_tag="U2R64_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HEM8919420.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="U2R64_002662"
     CDS             complement(1812..2297)
                     /locus_tag="U2R64_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919421.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2681)
                     /locus_tag="U2R64_002663"
     CDS             complement(2436..2681)
                     /locus_tag="U2R64_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HEM8919422.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="U2R64_002664"
     CDS             2874..3674
                     /locus_tag="U2R64_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8919423.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="U2R64_002665"
     CDS             3693..5561
                     /locus_tag="U2R64_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8919424.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="U2R64_002666"
     CDS             5554..6045
                     /locus_tag="U2R64_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HEM8919425.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /gene="srlA"
                     /locus_tag="U2R64_002667"
     CDS             6033..6587
                     /gene="srlA"
                     /locus_tag="U2R64_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEM8919426.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..>7599
                     /locus_tag="U2R64_002668"
     CDS             6605..>7599
                     /locus_tag="U2R64_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEM8919427.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1214 c         1442 g         2236 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acatgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gttcccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctg
//
LOCUS       DASHWW010000103         7159 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.105, whole genome shotgun sequence.
ACCESSION   DASHWW010000103 DASHWW010000000
VERSION     DASHWW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.105"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(131..325)
                     /locus_tag="U2R64_002669"
     CDS             complement(131..325)
                     /locus_tag="U2R64_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919428.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            complement(437..676)
                     /locus_tag="U2R64_002670"
     CDS             complement(437..676)
                     /locus_tag="U2R64_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919429.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            complement(790..1131)
                     /locus_tag="U2R64_002671"
     CDS             complement(790..1131)
                     /locus_tag="U2R64_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HEM8919430.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNEWFKMTLTNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            complement(1750..2082)
                     /locus_tag="U2R64_002672"
     CDS             complement(1750..2082)
                     /locus_tag="U2R64_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEM8919431.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(2929..3969)
                     /locus_tag="U2R64_002673"
     CDS             complement(2929..3969)
                     /locus_tag="U2R64_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEM8919432.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            5135..5221
                     /locus_tag="U2R64_002674"
                     /pseudo
     CDS             5135..5221
                     /locus_tag="U2R64_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            5781..5999
                     /locus_tag="U2R64_002675"
                     /pseudo
     CDS             5781..5999
                     /locus_tag="U2R64_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            6259..6513
                     /locus_tag="U2R64_002676"
     CDS             6259..6513
                     /locus_tag="U2R64_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8919433.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLIILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            6514..6831
                     /locus_tag="U2R64_002677"
     CDS             6514..6831
                     /locus_tag="U2R64_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8919434.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT         2361 a         1212 c         1042 g         2544 t
ORIGIN      
        1 gacgattaaa gcgactccta aaaaaccaaa taaccatttt ctcatccagc tacccccttt
       61 cagacaaaac aaaaaatctt tttctcattt ccatagaaaa agttttaaaa atgaattcta
      121 ttaatgaatg tcatgagact tctaacaata gttgacaatt agaacttgtt ttcacataag
      181 ttcgtctcaa ctgttcaaag tttttcattg aacctaacaa acaagctttc tcttttcctg
      241 ttatctgcat atcattgata tattgcatga cagataatct tttaaggtgt ttttgtttca
      301 tcgtttttag caacttttct tccatttatt tcgacacttt ttttctgttt tcgatttctt
      361 cataattcat gagttttcct accttccttg ttttttgcaa aaataaaaaa gcctatgatc
      421 acatacgctc tacacttcag tcttgggtta tctttttctt tcgtttaatt actggccgtg
      481 ctggtttcaa atccttgatt ccattatggg ttctccaata atcgaattct tttcgtaatc
      541 tttctttttc catatctgtt cctttagaca gggatttgaa tacatcttta ggtgaataac
      601 cacgagctaa cagctgtaca taccttcctt ttgtcaaagt atccatatcc atcgcctcta
      661 aaactggtcg cgccatctaa ttttcctcct aaatgaattc cttactcaat gcctaaggta
      721 atactacctt tttattattc gtcgtgactt cttctaagcc tttatctgta aaatttattc
      781 ctccagtttt tattcttctt tatccgctac aaattcaatg atttcaacgc tgacaatata
      841 atcactcaaa tatgaccaag tatcttcaac agataattcg tctccattat cattcgtaag
      901 cgtcatttta aaccattcat taccttcatc atcttcaggt agcaagccga atccaattgg
      961 attatcagtc aatttttgat agtataaatc atcctcgtct aatgctaaaa catctaatcc
     1021 tttacaattt ccgcctcttc taaacgtcac aaatcctttg taatcccaac gttggaaaga
     1081 aaccttaata gtatgtgtgc ccaatcgtat attcggatca taatttttca tttgtcattc
     1141 ctccattacg taaatttcat tttctctatg ttttatatca attttttcac tttattcagg
     1201 actcgttcat attttatcgt ttttcgttta cttaaaaata cataaaaaat atcgactcgt
     1261 ttatggcgtc cgaaacgaga aaccctagta gaaatcggta aatgctcgat tgatccaatg
     1321 accaacgtcc tcgcaagtat ctacatgtac tgcagcacac gacacaattt cttgtgcgtc
     1381 ctccccatta cgagaagacc tactccttat tccatgagtt tgcgtcaaag cctagatccc
     1441 ttagtagctg ctcatgatta atctaggcgc tattctaact tgtctaactt ctaaattccc
     1501 tcttgtttac tctgtgcata ttatttacac aaattcattt caccactatc caaacaaggg
     1561 catttactcg attgaccaat tttttacgtt accaatcgta aaaacctacc ccgtcacccc
     1621 ccgaaaggaa ttgttgatag atcaagtcta ctccttattt ttctagtaat tctaagttct
     1681 tttagaagtc tcgacaatat tttcaagcaa gcgaaaaacg ataaaataca agttatgaga
     1741 atgatcaatt cagctgatta aacgccccat cccttttgcg gtacaacgca agactccatt
     1801 ttttcttcga ccaatcagta caccgttttg gtcataaaca tgtttgattg ttggatatag
     1861 ttcttttaaa gggataggat cttttaaaat tatttgtttt tgtttaccag cgtaataaat
     1921 catttcctct gagactttgt ctttctggat tatatatttc ttacactgca caacggtttt
     1981 actttggcca gttgatagtt tcttcgtgat tttctctgta gcggtacacc gtttaccgta
     2041 gtgacaaata tcttcgagac tcaaaattcc tgtatatgac ataaaataat ccacccactt
     2101 actttaaata tttttaataa gtttttcttg ttatttttca aaaatagaga attgattttc
     2161 gttcatgaca aacaaaaaag agggaacgca tccaaacatg cgttccctct aatttcagcg
     2221 ttcgtcatac ggcaaagagc cacacggaca tttttataac attatgctta ggcatagatt
     2281 catcgtaata tcacgtattt ttaaccttaa cacagccaaa aaaagtggta tcacttttga
     2341 atatctgtta tactaaatcc gttgcgggta ataccgtaac actgaaaggt aaacgcatta
     2401 agggattaaa ggttgtctta atgccacctg tggacgtcga cgaaggttac cagccttccg
     2461 agtctcacag ggcctttctt ttttttgtat tttcaattgt ccaaatttat cgtccaaaag
     2521 tgcagaacga aaattaattc atcacaagcg tagcagacaa ttaaatttaa aacaactaaa
     2581 tttatacaaa aaaatgtaag cgaataatat tcgtattgcc tgaaaagaag taatatcaag
     2641 gtttttagct tttttaaaaa atgaaattac ctctcttcgc gtattattat aactaaaaaa
     2701 cagcaacatg caaacgtttg ttctcttttt tgtgttggaa attaattatt aactattaac
     2761 acttatgacg taaaaagcta cgtttgtgat ttttatcata atattttaac tcataaattc
     2821 tattaaaata gctatttctt tgtaacattt gtaatataat tagaataata aaaaattttt
     2881 aattttaatg ctactccatg aagcaacaat caatttgtca gtgaaatttc actctaacca
     2941 gtctttcgta atagtttttg ggaagctttc agaattcaaa cgtttttcac ttgatacttt
     3001 agcagctatt ggtttttcga taaaccaatt ttttacatag acaaaaatca ggttctggat
     3061 attttcaact ttttcggttt ttaatttttg ataggctttt aacagtgtcg tgtataattc
     3121 ttgttctgca ttgacataat aactatcgag ttcttcaaaa attattgaaa taccactttc
     3181 tgtttcggct tttttctttg cattatgaat agtctggaca gttttttgag cttcactgta
     3241 acttgaagaa aatgttttta ttaaatttaa tactcgttca gggataaacg tagcaatgct
     3301 gtcgtttgtc ataattgtct caaaattgtc taacaacaat tgatcttgta ggcggtcttt
     3361 ttcagtgtct atattgtgtc tattagtgtc taatatatta ttattaagtt ctggtatgat
     3421 tttcataccc tctgatttat caacgttttg gcacggtatg attttcatac cctcttgagc
     3481 cccaagggat tcagcgtctg atttttcgtc gagggtgggt atgattttca taccctctga
     3541 tttatcaacg ttttccctat tctctctatc aaatttttcg agtaagtaga tatcattttc
     3601 tgagactttt aattctgcta gatatagtct attaggatta tttttcccta actgtttgtt
     3661 aaatcccatc tgcttttgta ataataaacc aaaggattcc aactcttttt tgattgctat
     3721 cgctttttgt ttttggcagt ttaatacgct acatagttca tttgtcgtat aagtaaaata
     3781 aacattacct tcttcatcga tttgccgttt gctgattgcg atctctaatc ttgcttttaa
     3841 aagcatatag gcaatcttag ttgaatcttt catttttttg tattcgtcag aaacaataaa
     3901 gacttttgga aattgataaa ataattcgtt gtaaactcta tccgccttaa aaaaattaaa
     3961 atcagtcatt gtagatcctc tactttcaca ttgttttatt tatgtaaaat tacctactct
     4021 tttcgaaaat agcaaagata aataaaaaat gcaaacgcat taaaactgtt ttttaattaa
     4081 atactaccta aaatcagaaa taaaatgaat tatgtactac ctttaaagtc attaagaact
     4141 actttaaata aatattattt ataattaaat actaccagaa gaacgtatga ataaaattta
     4201 gttttaaaat taaagataat taagtactac cagtgtcaaa acaaaaaata aattaagaac
     4261 taccttatgc atataaaaca tactaccatt actagtaata tatactacct tatttcagta
     4321 gtatatatta tattcttctt ataagacaag gctttaggct agaaaacaat agattatata
     4381 ctactaaaaa atacaataag tactaccaat gtcagatata tataataatt atgtactacc
     4441 attaaaatta acttatttaa taagatacta ctgtgttaat ctgaaaaaaa ttactttaaa
     4501 gtagttacat actacctgtt aaattagata ctaccattaa tacttaaatt agatactacc
     4561 tatatttata ttaagtacta ccgttctagg aataagataa taaaaaaaaa ctaccaaatt
     4621 gcaattaaat actacttaaa atgtaaaaaa taagaactac ccaaattagg tagttcttaa
     4681 taagagaata tcagataaat ttgtacaagt cataaaaaaa ttaatcttaa atttttaaat
     4741 atatatacct gttaattata aactacttta tttaggtagt acataattaa cagataaaac
     4801 tacatgcttg tagtttgtct agctaatgag ttgcatatga tttatataaa ggtgtgcagc
     4861 ataacttagt tgaagttaag agaatagaat aaatattttt tgttttgcta ataattaaac
     4921 actacctaaa tatggtagtg tttaattata taatattcat tttgttacaa ataatcgtat
     4981 tataaaagca taacaattgg gataactatt ttttagatta tttaagtact acttaaatta
     5041 ggtagtactt aaattttggt ttaaggtagt aggtaattaa gaaataatat atatcttctt
     5101 ttataataga aggggagagg cctagttaaa agcagcgaca attaataaca atgtatttaa
     5161 tgcttcacaa aatccatttg gtggacaatg cattgttatt agcgatgatc taccgttcta
     5221 agtagttttt tctattggtt gcattcgtga ctaattatgg tataattatg agtaacaaag
     5281 aggtatttca ttatatcatc aaaccccatc agcgtgtagg ctgatggggt tttttttacg
     5341 tttctatatt atagaattaa ctggtaggct tactgtcttt tttggcaatt ttgcaatcaa
     5401 gccacttgca gatgtagtgt gcagttacct ctgcaaatgg cttgattgca aaaacaaaat
     5461 caaaaaggta tttcattata tctcctcctc cccttgccag attaggccgg ggtagcagac
     5521 agcaaaacta ttataacata actgaaatac ctaaatgaca tatacagata tgataattta
     5581 tgtattgatt tttctaacaa aagcacatat tttaatatat actacctatt ttaggtagta
     5641 tatattttta gatacaatat cgatcagttt tgaggaaatg aaattctaga tattttttgc
     5701 tacatagagt tactttcaat attttttaac gtaattaggc agaagtcact catcctctat
     5761 aggtttgtga tgaaattgct attgatccat ttaagtaaga gcaaaaaact ggaggtttat
     5821 caggtaattg gtctaatgga tttaagtatg cggtcaccgt gtatagagtt gcttatgaga
     5881 ttcaagaaaa taaagttatt ccagtattgc tatatggaac acatagcaat ttttatgaat
     5941 tagccgagaa cactcgcaac tttattcgtg tagatgaatc ggcttcggtt gagttataac
     6001 tttagctata tcaatcaacc gaccgacata tgttaaatct atatataata aaaataccta
     6061 cttaaatgga tgttaacgga agtgtatggt gagtagttca ctcgtatttt gatatcgttt
     6121 gtatatgttt tcagcgttct aagtggctta ttttgtccaa taataatatg gagtggaatc
     6181 ccttaagaaa caccgttggc aattgtcgtt ataacatgtt ataatttatt tatcaaaaac
     6241 taaaagaagt gtgataacat gggaaaagaa ctaaaggtta gaaagatcgg caatagcgtg
     6301 ggagtgatcc ttccaagctc tcttggatta aaaagcggag acactatcca agccaaacaa
     6361 gaaggcaact taatcatatt agatactact caaatagcaa aagaacacga tcgcaaattg
     6421 attgaagaaa gtttccaaga ctttgagaaa ggtttaacag tttcagaaat tgaaatggta
     6481 aaagctttcg gaaaatacgg ctggagtgaa tagatgaaag agtacacgct agtttattct
     6541 aaaagtttcc agaccagcct tgaaacgata atagaagaat gggaaaatga gcttgctctt
     6601 tctccagcca gcataaaaag atttgtaggt gcgatccaga aggctttaga actaaccaaa
     6661 aattttccaa ctatgcatga ggaagtttcc gaaatctatg gaatggatat cccaacatat
     6721 cggatcgtga tcggcaaaag ctatgcctta ttttatcgga tcgaccatga aaaaaaagag
     6781 atacttgtag gacgtatttt ccaatctaaa caaatgaaac taggctttta acaataatta
     6841 ggcaaaagtc gctcatcctc tacaggtggg tgattaatgc cgctcgatat ggttgttaac
     6901 cgtcggttac tcgaagattg atatataaga cttagtacct ttttattttg ctccatgtta
     6961 tggccgaagg tctaaagata caatcattag tctagagaaa aattaagaac cgtaggaact
     7021 acggggatcg cttggtgaat aagagacact gctattagtg aaaaaataag atatcaagta
     7081 cgctctattc ccaaaaattt cgtgacttta ctcatgagag gttcaagtag tatattttta
     7141 atcaaaattg acgtaactt
//
LOCUS       DASHWW010000104         6962 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.106, whole genome shotgun sequence.
ACCESSION   DASHWW010000104 DASHWW010000000
VERSION     DASHWW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.106"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..193
                     /locus_tag="U2R64_002678"
     CDS             <1..193
                     /locus_tag="U2R64_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919435.1"
                     /translation="GRMSELGYSMMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPL
                     VPKGYDFLDSISKLEKMND"
     gene            271..945
                     /locus_tag="U2R64_002679"
     CDS             271..945
                     /locus_tag="U2R64_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEM8919436.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            938..1102
                     /locus_tag="U2R64_002680"
     CDS             938..1102
                     /locus_tag="U2R64_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919437.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            1178..2320
                     /gene="dcm"
                     /locus_tag="U2R64_002681"
                     /pseudo
     CDS             1178..2320
                     /gene="dcm"
                     /locus_tag="U2R64_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            2310..2600
                     /locus_tag="U2R64_002682"
     CDS             2310..2600
                     /locus_tag="U2R64_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919438.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            2859..4043
                     /locus_tag="U2R64_002683"
     CDS             2859..4043
                     /locus_tag="U2R64_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEM8919439.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            4040..4177
                     /locus_tag="U2R64_002684"
     CDS             4040..4177
                     /locus_tag="U2R64_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HEM8919440.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            4923..6833
                     /gene="ltrA"
                     /locus_tag="U2R64_002685"
     CDS             4923..6833
                     /gene="ltrA"
                     /locus_tag="U2R64_002685"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8919441.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         2437 a         1118 c         1539 g         1868 t
ORIGIN      
        1 gggtcgtatg agtgaactcg gatattccat gatgtttggg gaggtcgaaa aaaacttctt
       61 tatgaagcac atcaaaggtc gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt
      121 ttatacgcca cttgtaccaa aagggtatga tttcttagat tcaattagta aattagaaaa
      181 gatgaatgat tgagtgatct tcaatactga ctttatactt caagtaacgt ataatacttt
      241 tatatagtag gaagaaaggg gataattaat atggaaagta atgattctta tttagagtat
      301 gcaaaagcaa ataaggataa gtttatttct tatattatca aagggaaatc ccccgaagtt
      361 ggacgagacg cagtttttat ggcagggagt cctggggctg gaaaatcaga ggttgccatt
      421 ggattagctg agaattatga taaccatgtg attattgatg cggattactt tcgcacccag
      481 tttcctgatt ataatggaaa aaactctagt ctctttcaaa aagcatcttc ttggttggta
      541 gagcaggcat ttagatatgt cttagatcat ggctattctt ttattctgga tgcaactttt
      601 gcaatattaa gtgctgaaaa aaatatctcg cgggcgttga aaaaacattt tcgagtgacg
      661 attttctatg tttatcaaga ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt
      721 gcagagggac gtcatgtgcc gaaaaaggca tttattaacg cttttttcaa atcaagagag
      781 aacattgcaa aagtaaagag taaacatcca gatgtattgc ttcatatcat aataaaagat
      841 tatacgaata atatttccga agttcattat gctacggata atctagaatt atttttacca
      901 ctagggtata gtaggaaaga tttggaggtt caattacatg actgagaaag aacaagtaac
      961 gaaaattgta aagaaataca ataagagcat tgcggattta tcggaaaatg ctactgcaaa
     1021 agagttcaaa acggtgatta aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt
     1081 agttggatta aataaaaaat agtaggacaa attaataatg tatgagccaa gagcaaaatg
     1141 ttcttggctt ttttctttgc aatgaatgag gtaatgtatg agatttttag atttattcgc
     1201 cggtattggt ggctttcgtt taggtatgga acaggcgagc catcattgta tcggtttttg
     1261 tgaaattgat aaatttgcta gacgtagtta taaagcaatt catgatacaa gtaaggaggt
     1321 ggaaatgcat gacatcacaa gtgtatcaga tgagtttatt caatccctcg gaccagtgga
     1381 catcctttgc ggcggatttc cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt
     1441 ttccgatact cgaggtactt tattctttga aatcgctcgg ttcaccactc ttctccgacc
     1501 taagctttta ttccttgaga acgtccgagg attgctcaat cacgaaggag gggctacgtt
     1561 cgagacgatc ctccgaacgc tggatggatt ggggtatgac gtggagtggt aggtgcttaa
     1621 ctcaaaggcc tacattcccc aaagccggga gcggatattc cttatcggac attctcgaga
     1681 cgcatgtacc gaacaagtat ttcctatcat tggaccgtct tcaacatctg atcaaaacat
     1741 cagaaatttg gtaaatatca atccttccaa tcgaggaatg ggtggacaag tctatggttc
     1801 agatggcgta gcgccaacct taacaggtga tgaaggaatc aaaatcgcac tgccagcaag
     1861 ggatggaatc tctgtagcag gactattacc gggaaagttt gaacaaggta atcgagttta
     1921 tgaagttact ggaaccgccc ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat
     1981 tcgaaaaaat gaaacagaat atcaagaggt gaagccagaa gacagtgtga atctggcttt
     2041 tcctaattcc acaagtcgcc gaggtcgtct gggaaaacag agtgttcata ccttactaac
     2101 aggagaccaa caagcgatcg tcacggatca gtatcaaatt cggaagctaa cacctagaga
     2161 gtgttggcga cttcagggct ttcccgattg ggcttttgat cgagattctc aagtcaattc
     2221 agatagtcag ttgtataagc aagccggaaa ctctgtaaca gttccggtca tttttgatat
     2281 tgccagaaga ttaaaagagt tggatgtaca tggtttatga tgagttgatt ggagaaattt
     2341 attgggtgat tggaaagatt cagtcagacc cagaattaga agaacaattg cgacggttaa
     2401 aatttgatat tcgcaagaat ggtgtcaaag tcgctggcga tccatattta atgaatgagg
     2461 agacggatgc tcgaattgaa ataaatcaag taattgcaga atttgagcgg attgcggacc
     2521 aagcaaaaga accagatatt cgtcaatact tgttagaaat gaaagcagag ttggaagtaa
     2581 atggtattac agatgagtaa cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga
     2641 ggattcgcga agcagaaatc ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga
     2701 ccatgatgtc tcacccccgt atctaacagg ggggtacaaa aacacaaaaa ataagtaagc
     2761 aaccattaag aatgcttgtt gtatcaaaga tagtaagtaa tttgtatagg tgttaactca
     2821 tttgaaaaag ttaacacctt gaatttggag gtgagaactt ggcacaacgg aatttagatt
     2881 atcggctatt aaaagaccga cgcaacgaat acggcgtttc acaaaataaa ttggctacgg
     2941 cttgtggact tagtcggccg tacttaaatc agatagaaaa tggtggcgta accgcatcta
     3001 taaaaaccat gaggaaaatt tttgaccaac tggaaagctt taatcccgat ttgcctttga
     3061 cgttactgtt tgactatgta aggattcgct ttcccacaac ggatgcacga aaaattattc
     3121 aagaaattct ccatttgaaa tttgagtata tgctccatga agattatgcc ttttactcct
     3181 atcaagaaca gtatgtcatg ggtgatattg tggtgatgtt gtctcatgaa gaagataaag
     3241 gtgtgctttt agaattaaag gggcgaggtt gccgacaatt tgaaactttt ttactcgctc
     3301 aaaagcgtag ctggtacgac tttttcgagg attgtctaaa ggccggtggc gtgatgaaac
     3361 gcttggactt ggcaatcaat gatcgagtgg ggctattgga tatacctgag ctaacgaaaa
     3421 aatgtcagaa ggaagaatgt atctccttgt ttcgtacctt taaaagttat cgttccgggg
     3481 aacttttaaa ggctgatgaa aaggacggca tgggcaatac cttatatatc ggcagtctca
     3541 agagtgaggt ttatttctgt ttgtatgaaa aagactatga acaatatatc aagttaggga
     3601 ttccattaga ccaaactgag acgaaaaatc gttttgagat tcgactgaaa aatgaccgtg
     3661 cttttcatgc gattcaagat ttgttaaaag gtcgtagcat tgagagcacc acgttttcca
     3721 ttatcaatcg ttacttgcga tttgcggata aagtagaagg taaaaggcga accaactggc
     3781 ccttgaatga acaatggggg cgttttattg gacggaatcg gaaagagatt caattaactt
     3841 ccgagccaaa accgtatacc attgaacgaa ccttgaattg gctaggccga caagtcgccc
     3901 ctacgtggaa aatggctaag gagttggatc gattgaatcg gacaacctat atccaggata
     3961 tggtacagaa tgcacgctta tcagaccgac ataaaaagat tttggagcaa caaagtatgg
     4021 caattgaaaa tttgattata tgaaaagagg aatcgtcatg ggaattgtaa aagatatttt
     4081 tttggtattt ggtggcagta tgcttggtgt tactgtgatg tgcttgatga atgcaagtgc
     4141 agcagcggat cgagcaatgg aaaagaaagg aaagtgacaa gatgaatttc ggacaaaatt
     4201 tatgtgcgac tcgttcctta gtgaaaagct aaggcactaa taaaagaacg aaaaagtttg
     4261 gttattagga gaactgataa tctgacaggt ggaatgatga agtaacgctc tgaaacgcct
     4321 gccctgagcc tccgacaagc attgtatgag gaaactcaga atgtttgaag ctcggtaaag
     4381 acggctgaaa gataccgtaa tagttgatga acatatatct tctatcgaaa actatccaga
     4441 ggtgggtagc gtatccaaca ggtcgggggt ctataaaata tctatggtta gaatgttcta
     4501 taaggaactg acgaaacagc gaatgtacgg gtctaaattt gaactttgta gaaatgcaaa
     4561 ggtacgagaa atcgtagctg gtgtggcaaa gtaagaatat aggttatgaa atgccatata
     4621 acgttacagg cggtatcaag ccagcaggct tatagctagt gacctaagga tatatatgta
     4681 tagataagat tatcggaacg aggaaaggta ttgggttctc atcaagagaa taaactgacg
     4741 aagaacaata agcagttgaa ctaatgctga aaagcagagg gcgaacctaa gaaattcttg
     4801 taatgagaat ggaggaatgc cctcaagtcg tgtatatatt agaaaagtat tatgttgttt
     4861 caataaggat tacgagtaag ataaaaaagc tcactcaatt tcaagtaaag gagtgaagcc
     4921 ttatgcctaa aaataaaaat gaaacattgt gtgtagaaga tttaagacac gctgaatatt
     4981 acgaaatgca aaacaccttt gatgatttat atgccaaaag taagaatgga gatattttca
     5041 ctcatcttat ggatattatc ctatcgagag aaaatatatt actggcatat cgaaatatca
     5101 aagcaaatgc aggcagtaaa acagcaggaa cagacggtac aataattaaa gatattggca
     5161 aattgccagc agaaacagtt gtcaaaaaag taagatacat tgttgcaggc agtccacatg
     5221 ggtatcgacc taagccagtg aggcgaaaag aaataccaaa accaaatggt aaaaccagac
     5281 ctctaggtat tccttgtatg tgggacaggc ttatacaaca atgtataaaa caagtattag
     5341 aaccaatctg cgaagctaaa tttagtgaaa acagctatgg ttttagacct aataggtcag
     5401 ttgaaaatgc aataaaagca acctataacc gcctacaaat cagccagcta cattatgtga
     5461 ttgaatttga tattaagggt ttctttgaca acgtgaacca ttccaagctg ataaaacaga
     5521 tatgggctat gggaatacgg gacaagcact tgatattcat tttaaaaagg atattaaaag
     5581 ctccaatcaa aatgactaac ggtacaataa catatccaga gaaaggaact ccgcaagggg
     5641 gaataatatc cccactacta gcaaacattg ttcttaatga gttagaccat tgggtagaaa
     5701 gccaatggca ggaaaatcct gttacaaaaa actatgtggt tcatatcaat aaaagcggta
     5761 gcccatgtaa aagcaacgct tacaaagaaa tgaagaaaac aaagttaaag gaaatgtata
     5821 tggttcgtta tgcagatgat tttagagttt tctgccgcta caaggaaagt gctgaaaaag
     5881 ccaaaatagc aatcactcaa tggattgaac aacgattaaa attggaagta tcacaagaaa
     5941 aaacaagaat tgtaaatgtt agaaaaagat actccgactt tcttggtttc aagattaaaa
     6001 tgataccgag aagaaagaag ttagttgtta aatcacatat aagtgataaa caattcaaaa
     6061 accaaaaaga caagctggta tcacaggcaa agaaaattgc ttctccctca aaagggaaaa
     6121 cggaattaga agaaacaaga ctttataatt caatggtatt aggtatgcaa aattattatc
     6181 agattgcaac gaatgtaaat ctggattgta tgaaactgaa tagagctgta atggctatct
     6241 tcactaacag attaggtaca aacaaaaggg gcagattgag aaaaacaggc agacaactta
     6301 cgacaaagga ggcaacaaga tatggtaaat ctaaaatgct tcggtatgtt gctggcgagg
     6361 gcgaacctat tttccctgtt ggatatatcc aacacagaaa accaatggca aaggtgtatt
     6421 tagcgaattg ctacactcta gagggaagaa aatttatcca caccaatcta agtgttgata
     6481 aattactgat gtaccagtta atgaaattat ctttggaaaa tcgcacaata gaatacgcag
     6541 acaatcgaat ttcgctattt tctgctcaac atggaaaatg tgctataact ctggaagaat
     6601 ttcaacaagc taatgaaata cattgtcatc atattgtacc aactggagct ggtggaaatg
     6661 acgattataa aaatcttatt ttggtaaaag aggcggtaca ccgtctaata cacgctaaaa
     6721 cagaagaaac aatacaaaaa tatatagctc tattgaagct aaataaagtc cagctcataa
     6781 gactaaataa atatagagta ttagctggca atcaagaatt aaacttgata taggtctact
     6841 acataaatac ttttcaatat aaacacgatg gaacgcggag tgcggtgaaa gtcgcacgct
     6901 ccgtgtgaat ggggggaaaa gtttgagata tttataatat caggaactta cctatccata
     6961 ta
//
LOCUS       DASHWW010000105         6719 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.108, whole genome shotgun sequence.
ACCESSION   DASHWW010000105 DASHWW010000000
VERSION     DASHWW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.108"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            70..153
                     /locus_tag="U2R64_002686"
     CDS             70..153
                     /locus_tag="U2R64_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEM8919442.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="U2R64_002687"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="U2R64_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEM8919443.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="U2R64_002688"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="U2R64_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1608..2273
                     /locus_tag="U2R64_002689"
                     /pseudo
     CDS             1608..2273
                     /locus_tag="U2R64_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2309..2554
                     /locus_tag="U2R64_002690"
     CDS             2309..2554
                     /locus_tag="U2R64_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8919444.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2657..3526
                     /locus_tag="U2R64_002691"
     CDS             2657..3526
                     /locus_tag="U2R64_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEM8919445.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3507..4241
                     /locus_tag="U2R64_002692"
     CDS             3507..4241
                     /locus_tag="U2R64_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8919446.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4274..5189
                     /gene="ant(6)"
                     /locus_tag="U2R64_002693"
                     /pseudo
     CDS             4274..5189
                     /gene="ant(6)"
                     /locus_tag="U2R64_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5186..5728
                     /gene="sat4"
                     /locus_tag="U2R64_002694"
     CDS             5186..5728
                     /gene="sat4"
                     /locus_tag="U2R64_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEM8919447.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5821..6615
                     /locus_tag="U2R64_002695"
                     /note="aph(3')-IIIa"
     CDS             5821..6615
                     /locus_tag="U2R64_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEM8919448.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2354 a         1010 c         1403 g         1952 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      241 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1501 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1561 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1621 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
     1681 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     1741 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1801 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1861 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1921 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1981 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2041 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2101 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2161 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2221 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2281 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2341 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2401 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2461 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2521 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2581 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2641 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     2701 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     2761 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2821 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2881 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2941 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3001 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3061 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3121 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3181 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3241 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3301 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3361 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     3421 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3481 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3541 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3601 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3661 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3721 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3781 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3841 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3901 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3961 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4021 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4081 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4141 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4201 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4261 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4321 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     4381 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aacctagaac
     4441 cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg atgcaaaagc
     4501 cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt atgctatttg
     4561 atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat aattacctaa
     4621 agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa agggacatag
     4681 ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat gatgattgct
     4741 gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgt aaggaaattt
     4801 tatttgctat tgatcatttt aatcagattg ttcgccatga gctgctgaga atgatatcat
     4861 ggaaggtcgg catcgaaaca ggctttaaat taagtgtagg caagaactat aagtttattg
     4921 aaaggtatat atccgaggat ttgtgggaga aacttttgtc cacctaccgg atggattcct
     4981 atgaaaacat atgggaagca ttatttctat gccatcaatt gttcagggcg gtatccggtg
     5041 aggtggcgga aaggcttcat tatgcctatc cggagtatga taggaatata acaaaatata
     5101 ccagggacat gtataaaaaa tacactggta aaaccggctg cctggatagc acatatgccg
     5161 ctgatataga agagaggcgg gaacagtgat tacagaaatg aaagcagggc acctgaaaga
     5221 tatcgataaa cccagcgaac catttgaggt gataggtaag attataccga ggtatgaaaa
     5281 cgagaattgg acctttacag aattactcta tgaagcgcca tatttaaaaa gctaccaaga
     5341 cgaagaggat gaagaggatg aggaggcaga ttgccttgaa tatattgaca atactgataa
     5401 gataatatat ctttactacc aagacgataa atgcgtcgga aaagttaaac tgcgaaaaaa
     5461 ttggaaccgg tacgcttata tagaagatat cgccgtatgt aaggatttca gggggcaagg
     5521 cataggcagc gcgcttatca atatatctat agaatgggca aagcataaaa acttgcatgg
     5581 actaatgctt gaaacccagg acaataacct tatagcttgt aaattctatc ataattgtgg
     5641 tttcaaaatc ggctccgtcg atactatgtt atacgccaac tttgaaaaca actttgaaaa
     5701 agctgttttc tggtatttaa ggttttagaa tgcaaggaac agtgaattgg agttcgtctt
     5761 gttataatta gcttcttggg gtatctttaa atactgtaga aaagaggaag gaaataataa
     5821 atggctaaaa tgagaatatc accggaattg aaaaaactga tcgaaaaata ccgctgcgta
     5881 aaagatacgg aaggaatgtc tcctgctaag gtatataagc tggtgggaga aaatgaaaac
     5941 ctatatttaa aaatgacgga cagccggtat aaagggacca cctatgatgt ggaacgggaa
     6001 aaggacatga tgctatggct ggaaggaaag ctgcctgttc caaaggtcct gcactttgaa
     6061 cggcatgatg gctggagcaa tctgctcatg agtgaggccg atggcgtcct ttgctcggaa
     6121 gagtatgaag atgaacaaag ccctgaaaag attatcgagc tgtatgcgga gtgcatcagg
     6181 ctctttcact ccatcgacat atcggattgt ccctatacga atagcttaga cagccgatta
     6241 gccgaattgg attacttact gaataacgat ctggccgatg tggattgcga aaactgggaa
     6301 gaagacactc catttaaaga tccgcgcgag ctgtatgatt ttttaaagac ggaaaagccc
     6361 gaagaggaac ttgtcttttc ccacggcgac ctgggagaca gcaacatctt tgtgaaagat
     6421 ggcaaagtaa gtggctttat tgatcttggg agaagcggca gggcggacaa gtggtatgac
     6481 attgccttct gcgtccggtc gatcagggag gatatcgggg aagaacagta tgtcgagcta
     6541 ttttttgact tactggggat caagcctgat tgggagaaaa taaaatatta tattttactg
     6601 gatgaattgt tttagtacct agatttagat gtctaaaaag ctttaactac aagcttttta
     6661 gacatctaat cttttctggc tctttgtcaa atgatgttgg taaagagaaa tcttagaat
//
LOCUS       DASHWW010000106         6644 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.109, whole genome shotgun sequence.
ACCESSION   DASHWW010000106 DASHWW010000000
VERSION     DASHWW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.109"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1..859)
                     /locus_tag="U2R64_002696"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="U2R64_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="U2R64_002697"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="U2R64_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEM8919449.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="U2R64_002698"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="U2R64_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="U2R64_002699"
     CDS             complement(2143..2373)
                     /locus_tag="U2R64_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HEM8919450.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="U2R64_002700"
     CDS             complement(2603..3421)
                     /locus_tag="U2R64_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8919451.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="U2R64_002701"
     CDS             3582..4271
                     /locus_tag="U2R64_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEM8919452.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="U2R64_002702"
     CDS             4285..5787
                     /locus_tag="U2R64_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8919453.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="U2R64_002703"
     CDS             5800..6276
                     /locus_tag="U2R64_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8919454.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="U2R64_002704"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="U2R64_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DASHWW010000107         6639 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.110, whole genome shotgun sequence.
ACCESSION   DASHWW010000107 DASHWW010000000
VERSION     DASHWW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.110"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1273..1938)
                     /locus_tag="U2R64_002705"
     CDS             complement(1273..1938)
                     /locus_tag="U2R64_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919455.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2118..4100
                     /locus_tag="U2R64_002706"
     CDS             2118..4100
                     /locus_tag="U2R64_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEM8919456.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4104..4742
                     /locus_tag="U2R64_002707"
     CDS             4104..4742
                     /locus_tag="U2R64_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919457.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4770..5198
                     /locus_tag="U2R64_002708"
     CDS             4770..5198
                     /locus_tag="U2R64_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919458.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5655..6566
                     /locus_tag="U2R64_002709"
     CDS             5655..6566
                     /locus_tag="U2R64_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8919459.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADNGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         2286 a         1006 c         1220 g         2127 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgaggacta cctgtattag tcctcttttt
       61 tgaccagatt ttgaccagtc tattttacat tctaatatat tcatatgagc taattttatg
      121 attaaatggt aagtgtttcc ttgtttgttt tagtttaaac tagtgtgtaa tttaaaaatc
      181 tatatggaag ggtctgtggg gtaatactta aataaaggct aggaacctga taacatcaag
      241 gttcctagcc tttttataat aaaatgaagc gaaaataatt tcttttaaag agccgagatt
      301 atcagctata taagagtgaa tttgatgcaa aaaacagagc cgaaacagtc ttggtgttcg
      361 tagctctgct tatatgtttc gaatttaaga caaagagttg gcaaaagatg ttgataagga
      421 agataagata actgtgttat ataaactagg taactaactg taacaagcta attttaagag
      481 attcttatta gaagacgttt aggaatataa ctaagaaaat gattatacag gtaattgtca
      541 tttcaataat gttttctaat tttcgcgtct ttgttttaag aaaaaggcca gaatcagttg
      601 gaaaaaagtt cgtacgatag tgaagagggg caaaatttcc tactaatatt cccactaaca
      661 agagataaaa cggccaggtt ggtgtgattc ctctataaaa aaatgcccat gctaccgaaa
      721 tcccatagat taacaactga acaattttta caatgaaaaa attgttctgc cattactcaa
      781 agtctcttcc tccttgtatc gtttatttgt ttcattttat cattatgata ggcgcttgaa
      841 caatccattt tgtattttat tgagtactct tggataaact accagcgatt atcatattta
      901 tttatgttac tgtaagccat catataaaag taaatgagca gatcatagaa atataaaaaa
      961 gaactaaaat tgatctaaat tatgtgcagc ttgactacgt accaatctat attacttact
     1021 agattggtcg ttaatctatt cggatcgaat gagcaaaata tttttgtgaa tgtccatcct
     1081 tgattatgat tccaaaaaga atcattggga ggctgtggcg taaatattat actataagcc
     1141 agaaatacct atcattctga acttttttat ttaggaactt tcatctcaag gctttttcaa
     1201 ttaatttgta cccctgtttt ttggataaga tcatgtgcat tgattttttc tatctctacg
     1261 ttcatctcct acttaatgcc tatctggctc ctgagggctt ctttttaagg cgtcgtcata
     1321 gtcttggctg aggatttctt ggtaatctga gggaatggct tcccaagtga gcaggcgaac
     1381 gttcatgacg tgttttcctt tgtgtttgat tacagcatgg ttcttctctt tttctacctc
     1441 tccagcgtga aaagacagcc atgtaccatg gccaaagata tcattacata cccaacgttc
     1501 gatggaattg tccacgtatc ctacagggag tgtggtatag ccgatttgtg gtttcaaaaa
     1561 aggattgaat cgatcgatcg tttcattttt gtattgataa ttgataagaa aaagatagac
     1621 caaacaaaag acgagcagaa agaaagatag tgtctttttg agtgagaagg gttgttttga
     1681 tgaataagat ttcttgttaa caagaggttc atctggcaat gttggttcta ttgattcggt
     1741 agctgattca atagaaggaa aatcaatcgg cagacctaaa gtatgatgta aaagtgacag
     1801 catttcaagg tctggcattg tacgagaatt ttcccaacta gaaatcgttt tatcggaaac
     1861 accaattttt tcgcctaatt ctttttgcgt aagcttacaa tttctgcggt aagttcgtat
     1921 tttttctccg gtgttcatct tcttctcctt tcgattctac agtatataga tttattctac
     1981 atgacctata cacttgatag atacgttttt ttgatgaaaa acggtatgat tttatcaaag
     2041 aatcatttaa gtaagggaga gtggtgataa tcaaaaaaaa gttcacagtt ttactcacaa
     2101 tcatagtgac cggtatcatg agtggttttg ccttggttag tataaataaa caggtactct
     2161 atcggacaaa tgaatttttc catcaaacag atacttatac tccgattcga ttgccacaac
     2221 attttattgg gcaagaagaa tatgagcagc taatcatggt atttgaaaat gtctcatcag
     2281 aaactgagct ttcttatatg aaaaaaacag taaatgaatc caatgaagta gatacatctt
     2341 ggaacttcaa gatacagcca aagcttgaaa tgacattgta ttatcaaggg gatgtcaaat
     2401 cttctcacga gaaggtaccc tattctaata cctcctttcg cgtaacgtcc attgaagaat
     2461 cgatcaaaat aaaagatttt gaaggtgaat ttttcttgat gacgagagaa aaagaagcct
     2521 atgaacggtt catttcacta ttcactgatc gattcaatca agcatttcac actgattatg
     2581 ccactaatat ttttgaagac tttgaaaata gctattcgta ttcggttatt tcaaatacag
     2641 acgtatataa ttatcgagtg tatttaacta ttggattgat tcttttattc cttttgttat
     2701 catccttttt cttattgatg aataaagaaa tcagtttatt gttgaataat gacttttcat
     2761 tacatcaagt attgtggtgt ttattgggga aaaagaaaat cattattaca ttcataattg
     2821 caggaatcat tggtggtttt atttttatgt attataagga gcaatttctt tatttgttcc
     2881 agatgtacgt tttcttgttc agcggaatat atggtatctc tttgatttct cttttattag
     2941 ttgaaaaaat cgcttcgtta agagaagcgt tcaactatat ccaatacatt ctttttacat
     3001 ttggattgtt gttttctctt cttttgaccg ttgccaatgt cgaattagca actatcgttt
     3061 tttcttcttc acagttagct gtttcccatg aaccaccaaa agaaatcgct ggtgaggact
     3121 atcatgtatt ttatccagta accatcggga aaaaccacgt ggattttatt tattccaatc
     3181 gttttgcatc agcagcagat caggaattat atgaaacttt gaataaaaac ggaagtatat
     3241 tagtcaatgt atcagattac ttgaatgaag aaaatgaaca gtttggcaga gggataaaaa
     3301 taaatctgaa ttatcttaag aaatttcctt tgattgatgt ctctggaagg ttgatccaaa
     3361 taaccgaaaa agaaacgcac cctgttatat tgatccctga acgatataga catacagatt
     3421 taaaaaatga cctggcgcaa ataacagaat attatcaaga aatcagtgaa aaagaaccga
     3481 aatttctatt tataaaaaac aatcaaccca tttatacatt tattccttct atcccctgga
     3541 tcgaacatta tccggttgtt gaaatactga cattgaaaaa cagtatgtat ttggaaagaa
     3601 atattctcag cggagaaatc tatccaccgt taaagatcaa gataggctct ttgtcgaaag
     3661 aaaggttatt tgagctgatt gaagaaagtc agttacgtga taacttgcag ttatcatttc
     3721 cgtatactca gactgaagag atagctgtca aagtgttaag cagatcattt cattacttga
     3781 tacagatatt tttactcact ttcttttctt tcttcttgtt gagctatgtc atgttatgca
     3841 tatattttgt ctacaattgt cggaaaatcg ctatctttcg ttcaagtggt tattcgctct
     3901 ttgaaacgta taaagatttc ttcatgatga acctcatcaa atggggaacg acaagtgtaa
     3961 tcttcctttt tcttatagaa agagagccta aatatctttt taatattttt ttctttagct
     4021 tcattgattt tattctttca gttgttttta ttttgtctac agaaaagaaa agtcagttat
     4081 tgctgatgaa tggaggttaa caattggagc cgttgatagt gataaaaggt gcgaaaaaaa
     4141 tcattcgaaa caaaacgatt cttcatttgg atcgtttcac tgcggatgct ggggatcttg
     4201 tgactgttgt tggagaaagt ggagcaggta aaagtacgtt attgaatata ttaggattga
     4261 atgatcagtt cagttcagga caattctatt tgttcgatca agagacgaaa caattaactg
     4321 ggagagagaa gcgcttgata aaaagaaata ccatatcttt tctttttcaa gattttgggt
     4381 tgattgaata tgaaacaatc gattttaatt tagatattgg attgaagttt tcgaatttaa
     4441 atgtttcaga taagcgaaca gcaaagtatg aggcattgaa aaaagtaaat ataaacaaga
     4501 agctaagtac gcctatctac acattatctg gtggtgagaa gcaaagaatc gcctgtgcga
     4561 gagtcttatt gaagaatagc aaaatcattt tagccgatga accgactggg tcattggata
     4621 aaagaaataa ggataaagta gttgaaatct tatcgcaaca agcttcccaa ggtacgttag
     4681 ttatcgtagt cacgcatgat ccatatctga ccaaaatagg aaacaagaag atcatgcttt
     4741 aaaaatcaaa aaggaaagga tgtcgtttta tgaaaaaagc agttattatt tgtgcactag
     4801 ggataggttt tgttggagga aacgctatgt catctgaagt ggaagcaaat tcagttcacg
     4861 gtgaaatcta ttacaaatct ttaaagccag gagagattca ttttgatgct aaaggtaata
     4921 ttattaagtc aaatttacca gtagaccggg aaatttctag aacagcaatt aatcatagct
     4981 ctggaagatg ggtttattat agtgatacaa cttgtacgag aaaaacaggt cattctaacc
     5041 actatagtcg tgtctataat cgtcacggtg caaaagcgaa agttggaaac tctattcgat
     5101 cagcaaatgc aacaaaagga gtatgggcct atgcaagtgc gacaggaaat agaactgaca
     5161 cattctcatg ttggtacaat ccaaccggtt ggtattaagt atccaaaagt ttatataaaa
     5221 tagaaaaaac atataatgaa acagcgttaa aagttatttt tggtagtttt aatatattca
     5281 tttttagttg tataaaaata tatcataata aaaacaacaa aaaaatgtct ggaaaatcga
     5341 acataaaagt gtctgatttg aatatcccag cagcggaaga agaaaaacaa aatcgataac
     5401 atttgttcta agaattagtt acgttaaata cggaacgcaa gatagacttg aaaaacggta
     5461 acaaaagaag tagtatatta aggtgtgatg tgctacttga catttattct gctgagcgaa
     5521 ctttctggat tgtgtagcct tatatctatt caggacgtat cgagcagatt agtaaaggtg
     5581 ttcttgatga ttttcatctt gaacaccttt gtttttagca attcgcaaaa aacgaaaagt
     5641 aggagaattg ataaatgaaa aaaagatttt tagcacttgc catcgtacta ggcactggct
     5701 tattgtcagg ctgtacgaat gccggtgaaa aaacagccgt tagttataaa ggcggtacaa
     5761 tcagcgaaca agaagtaatg gatagcttga aaaaaatgca aggagcagat tccgctgtgc
     5821 aacagttgat cgtttatcaa gtatttgaag ataaatatgg agatgacgta tcaaccaaag
     5881 aaatcgattc tcaatatgat caaacaaaga aacaattggg tgattcattt gattcacaat
     5941 tgaaatctgc aggttacaca gaacaaacat tcaaagacag tatcaaacaa agtctagcct
     6001 ttcaagaagg tctaaagaaa catatcaaat tgaccgatga agatttaaaa acggcttggg
     6061 aatctttcca tccagaagtg gaagctcaaa ttatccaagt agcaagtgaa gatgatgcaa
     6121 aagatgtgaa gaaagctgct gataatggag acgatttctc taaattagcc aaagacaagt
     6181 caactgatac tacgacaaaa gaagatggcg gaaaagtgaa atttgattcc actactacaa
     6241 cggttccggc agaagtcaaa gaagcagcct ttaagttgaa agatggtcaa gtttctgatg
     6301 tgatcacttc taccaatgct tcaacttata ctacggaata ttatgtggtt aaaatggtga
     6361 aaaaccaaaa caaaggcaac gacatggata aatacaaaaa agaattgaaa gaaattgcaa
     6421 cagacacaaa attaagtgac agtaccttcc agaataaagt aattggcgaa gtattgaaag
     6481 acgctaatgt aaaaatcaaa gacaaagact ttgaaaatgt tttgagtaca ttcacttcag
     6541 attctagtac agcaagtagt aaataagcgg tataaataaa aaatatgaac tatttaaatc
     6601 aataaaactg ttcatctaaa tctttttatt agaactaaa
//
LOCUS       DASHWW010000108         6622 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.111, whole genome shotgun sequence.
ACCESSION   DASHWW010000108 DASHWW010000000
VERSION     DASHWW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.111"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(99..1229)
                     /locus_tag="U2R64_002710"
     CDS             complement(99..1229)
                     /locus_tag="U2R64_002710"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEM8919460.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="U2R64_002711"
     CDS             complement(1878..3080)
                     /locus_tag="U2R64_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8919461.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="U2R64_002712"
     CDS             complement(3140..3343)
                     /locus_tag="U2R64_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEM8919462.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="U2R64_002713"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="U2R64_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="U2R64_002714"
     CDS             4880..5692
                     /locus_tag="U2R64_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919463.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         2015 a         1333 c         1034 g         2240 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagctgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gt
//
LOCUS       DASHWW010000109         6460 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.112, whole genome shotgun sequence.
ACCESSION   DASHWW010000109 DASHWW010000000
VERSION     DASHWW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.112"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(105..560)
                     /locus_tag="U2R64_002715"
     CDS             complement(105..560)
                     /locus_tag="U2R64_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919464.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(714..1922)
                     /locus_tag="U2R64_002716"
     CDS             complement(714..1922)
                     /locus_tag="U2R64_002716"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEM8919465.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2034..2366)
                     /locus_tag="U2R64_002717"
     CDS             complement(2034..2366)
                     /locus_tag="U2R64_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEM8919466.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2514..3389
                     /locus_tag="U2R64_002718"
     CDS             2514..3389
                     /locus_tag="U2R64_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8919467.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3471..4052)
                     /locus_tag="U2R64_002719"
     CDS             complement(3471..4052)
                     /locus_tag="U2R64_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HEM8919468.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4058..5317)
                     /locus_tag="U2R64_002720"
     CDS             complement(4058..5317)
                     /locus_tag="U2R64_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEM8919469.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5319..6365)
                     /locus_tag="U2R64_002721"
     CDS             complement(5319..6365)
                     /locus_tag="U2R64_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919470.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1798 a         1338 c         1101 g         2223 t
ORIGIN      
        1 cttgtcacag tcccttattc tgaataaacg gtgtggaaga gacagcctat cagtagtaat
       61 aagacacatc tctttcacag cctcattttt gcgtaaaaat cgatttattc gaaaaattcc
      121 ccgtatacat cttctacacg ttgatctgga ttgatcacga tatacaagtt acctgttttt
      181 tcgctgattt ttgttgattg atattgattg tctaatcctt ctgttccttt atctagatat
      241 gggaagtaca caagatcagg tgtgccattt cggtaaagga tttccattcg ctcgatatct
      301 tcgtatttca atgcgcgatt aaacatgccc atttccagtc cgcctaggtt gatatcatgt
      361 gtcgcaactg cgtccccttc atggaagatt tcgattttaa atccagcaca cggatggatt
      421 tcaacaaatt cactgccatt gattcgtcca aaacttgttg tgatttgttt gatccaaaga
      481 tcgccgatat gacggcggtt gatcgtccag gtttctccat ttctaaaata aaattttagc
      541 gctgtcattt ctttactcat taaaaagact cctttatgat gtaatttatt cttgtactac
      601 ctcagtttag cacaaattta tgtaagtggt cacatcttat gttttttctt ctaatgacgt
      661 atctgcccac tttaagtagc caacaaagct gagcagatac agtctagtgt tttttaaatc
      721 aatttttctt tcgataaaaa atccaaaacc tgttttttat cattttttat tctttgttct
      781 acgacggctt tttcagctaa ttgcaaagct tcactaaccc acttaccagg tttttttcca
      841 gtttcttcta gcaagatttt accatctact gctaattcgc ttaatgactt gataggtaaa
      901 cgatcatagg attctcctac ggcatccatc tgaggtgttt cgtcaaaata gatcatcaat
      961 tcttctactt gcagtgcatg ttttttgcct aagaagtaca attcgaatgg ttccaaagct
     1021 ccagtttctc gttgtcgtag tccttggaca agtgcttgaa cgtctttaat catttggtta
     1081 gaacacttcc acgatttcaa aaaggaacga atctcatttt cttttagatc cagttggctg
     1141 atcaataatg cccatgcttg gctctcttct ttcaatggga cggatggtaa ttcagcaaaa
     1201 cgtaaaagtg cttcgccttc ttctttcaaa ccgggacagc aaatgtagca ctctgtttca
     1261 ataaatgcat ggattcccgc ggcccgttca tttcccaaga gcatcttgat gaattccaca
     1321 tttatacgtt ctacagatat tttacctaat agctcgtggt tttctttgat ggcgtagaag
     1381 gtttcttcct ctaatttgaa ccctagttga ctgacaaaac gcaacccgcg catcattcgt
     1441 aaggcatctt catggaaccg ctcatgagga ttgcctacag ctcgcaagat ctgttcttct
     1501 agatcttgca gaccatcgaa caaatcgatg atttctccat cttctttcaa agcaaacgca
     1561 ttgatcgtaa aatctcttct tttcaaatct tctgccaacg aacgaacgaa ttcgacatga
     1621 tctggtctac ggtagtcctg ataagttgat tccgtccgaa atgtggtgat ctcatattgt
     1681 tcatcatttt ctaataccaa cacagttcca tgttcgatcc caatatctat cgtttttgga
     1741 aaaagctgtt tgatttcttc tggaaatgcg cttgttgcga tatccacatc atggattggc
     1801 tggttcagca agatatcacg aacacttcca cctacaaaat aagcttcata tcctgcattc
     1861 tctaattttt tcagaactgg aattgccttt tggtattcca gaggtaattg ttttaatttc
     1921 atttttccaa cctttcctgc gtgtttcttg tcctgagata aagactcagt tgcatggtga
     1981 ctgtttgaca agtccgtttc agagtcttca aggccaggac cacttcatct tgtttactcg
     2041 tccttacgct caaagcgatt atggtctctt tgattgaatt tttccatgtt tttttcaaaa
     2101 acttcagtta agtcgatatt caatgaatta gccatgatca tcgtaacgaa taaaacatca
     2161 ccaagttctt ctgctaccga gttaactggt tcagaagcct ttttgctttt ttctccataa
     2221 gtgtggttga cttctcttgc caattcacct acttcttcag ttaatcgagc catctgagct
     2281 aatggagaga aataccccac cttgaattgc tggatatatt catccacttc ctgctgcata
     2341 ctgtataaag aacgcttttt atccatcttt ttccctccaa aactatctta ccaaaacttt
     2401 aacgcaaatc ctagataaga gcacttgaga aaatcgaatt tccatgctac atttaggaag
     2461 gaatttctaa atggaaattc tgtgaaaata cataattgaa agctggaatt catatggtca
     2521 aacgaaaaac agtaaaagaa gttcttttta tcattatagg aacaagtatt tatgcatttg
     2581 gtcttgttta cttgaacatc gctaatcatt tagcagaagg gggagtctca gggatcacct
     2641 tgatcttaag agctttattt ggtattgatc cagcttatac gactttatta atcaacatcc
     2701 cattgatttt actaggagga aagatcctcg gtaaacgttc cttggcctat actgttctag
     2761 gtacactttc tttgtcattc tttttatgga tctggcaaag ggttccacta gaaatcaatt
     2821 tacagcatga tctactgatc gtttctctac ttgcgggttt agttgcaggt gtaggaagcg
     2881 ggatcgtcta ccgcatgggt ggaacaacag gcggcagtga tattatcgct cggattttag
     2941 aacaaaatta cggcatcact atggggcgtt ccctattggc atttgatatc atcgtcttac
     3001 ttgcttcatt aacctatatc gacttgaaac gtatgatgta tacgttgatt gtttcgtatg
     3061 ttttcagtcg tgtgattgat tcgatcttag atggcggata ttctgcaaaa ggtctacttg
     3121 tcgtctccaa caaaagcgaa gagattgcac cactactgat gaccggtctg caaagaggtg
     3181 tgactttcct ttctggagaa ggcgcattct ctggtaattc aaaaaaaatc atctatatgg
     3241 tcgttagctc tagtgaatta actgaagcta agaggatcgt ccacgagatt gacgaaaaag
     3301 ctttcctttc aatcatcaat gtgcatgaag tggaagggca aggctttact tatttgaagc
     3361 cacagacaag attactgaaa aaactataag aaaaaagaca aagataggct atgaggaaag
     3421 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
     3481 tgttcactta cccggttact tttcttttgt gtctgcaaaa gaatctttcg gttaacttca
     3541 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
     3601 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
     3661 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
     3721 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
     3781 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
     3841 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
     3901 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
     3961 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
     4021 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
     4081 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
     4141 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
     4201 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
     4261 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
     4321 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
     4381 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     4441 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     4501 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     4561 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     4621 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     4681 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     4741 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     4801 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     4861 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     4921 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     4981 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     5041 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     5101 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     5161 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     5221 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     5281 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     5341 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     5401 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     5461 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     5521 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     5581 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     5641 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     5701 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     5761 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     5821 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     5881 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     5941 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     6001 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     6061 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     6121 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     6181 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     6241 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     6301 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     6361 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     6421 agataagagc aaagctcacc tcataacttg gaaataaata
//
LOCUS       DASHWW010000110         6415 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.113, whole genome shotgun sequence.
ACCESSION   DASHWW010000110 DASHWW010000000
VERSION     DASHWW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.113"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..115)
                     /locus_tag="U2R64_002722"
     CDS             complement(<1..115)
                     /locus_tag="U2R64_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8919471.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="U2R64_002723"
     CDS             246..698
                     /locus_tag="U2R64_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919472.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="U2R64_002724"
     CDS             712..1401
                     /locus_tag="U2R64_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919473.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="U2R64_002725"
     CDS             1526..3877
                     /locus_tag="U2R64_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HEM8919474.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="U2R64_002726"
     CDS             3957..4352
                     /locus_tag="U2R64_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919475.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="U2R64_002727"
     CDS             4677..5294
                     /locus_tag="U2R64_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919476.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="U2R64_002728"
     CDS             5335..5634
                     /locus_tag="U2R64_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HEM8919477.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="U2R64_002729"
     CDS             5668..5835
                     /locus_tag="U2R64_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8919478.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6404)
                     /locus_tag="U2R64_002730"
     CDS             complement(5880..6404)
                     /locus_tag="U2R64_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919479.1"
                     /translation="MDKLFQEKASGKDTERPEFQKLLNYIREGDCVIVTSLDRLGRDY
                     EDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSLLSYIAQNEREKIR
                     ERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQGIPVAEIAKENGI
                     SRPTIYKIKKANDL"
BASE COUNT         2201 a          897 c         1268 g         2049 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tcctt
//
LOCUS       DASHWW010000111         6362 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.114, whole genome shotgun sequence.
ACCESSION   DASHWW010000111 DASHWW010000000
VERSION     DASHWW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.114"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1530)
                     /locus_tag="U2R64_002731"
     CDS             complement(<1..1530)
                     /locus_tag="U2R64_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919480.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LE"
     gene            complement(1586..4066)
                     /locus_tag="U2R64_002732"
     CDS             complement(1586..4066)
                     /locus_tag="U2R64_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919481.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            complement(4050..4385)
                     /locus_tag="U2R64_002733"
     CDS             complement(4050..4385)
                     /locus_tag="U2R64_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919482.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            complement(4399..5433)
                     /locus_tag="U2R64_002734"
     CDS             complement(4399..5433)
                     /locus_tag="U2R64_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEM8919483.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            complement(5523..6203)
                     /locus_tag="U2R64_002735"
     CDS             complement(5523..6203)
                     /locus_tag="U2R64_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEM8919484.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
BASE COUNT         1845 a         1280 c         1165 g         2072 t
ORIGIN      
        1 ttctaaataa cattctttta aaaattggtt caaatagggg aaatcataat tatattcgtt
       61 gctagtgaat acaaaaactt tagcggactt ctgtgacggg tactctttca attggctagt
      121 caaaatgata tcatactgct tttctttctc gtattcgact aaatcatatt tgatcgtatt
      181 cagcaattgt tcctggatga tttctttcac gatatccgcc attagccttt cataaggaag
      241 atcataagca atttgcagac gtaattctaa ctgcttgatc agcgtccgta aaatagatgc
      301 atagcgagca aataattcaa agcgggcatt ttcctcgtct acttcagtaa aatcaacaat
      361 agcaaatgtt tgtctgacca atctttcaca taaaaccagg aattgtttat cttctacttc
      421 agttaaccgc tgttttaatc cttcttggcc aaaaatattc atccatcctc taaaataggc
      481 aaaatgagcg tgattttgca tcactgtcaa cgcaatcttt tgcgaaatct cttctggaaa
      541 aacataaaaa gagaaatatt cttctatcga ttgtttaaac gttcgattca attgagctac
      601 tacgtcgtct ttgtattttt cgcttatcaa aaactcctgg acatgcgagt tatgtgtatc
      661 taatgtaaag ttactgatca tgaaaagata aaaaaccaac gtttcatttt gattccaagg
      721 aaaggcatat tgaaagaagt aacgggtcaa aaatgtatgg aggtccaata aaaattgtgt
      781 cgtttgaaac aatccaacag gaagattgct ataatctggt ttggattttt tcgtacagcg
      841 cattcgcttc ttcataatgg aaagccatat ttcaaatttc aatcgtcctt cttctgtaat
      901 agcaaaacta aactcttttt gcagcagatc taaaaaagtg tttcctgata aatcactgta
      961 ttcttttttg ttttcaagat agggacgtcc aaaccaaaat aattggaaat aaaaataacg
     1021 aatttgactt tctggaccgg tcagccgccc gctttttatt ttcagatgaa actcatttaa
     1081 agaatcattt aattccttca ctctgcgaga caaagtagcc gaactgatat taagttccat
     1141 gacaagtttc tgccgatcaa atgagccatt ttccaacaga taaagaagta tctgatattt
     1201 tgtagaatag cgcaagtaac aatgataata aacatcgact gctgctatat ttccatgtct
     1261 gattaataaa atattccctt cttggataac aatttccaat tgtttgatat tttccaagtt
     1321 agcttgtaaa taaaacagat cttctttcaa ggtagcccga tcaactgata agcgggtaag
     1381 tacgttatta acggaaacct ctcctttttc ctctaataaa agttggaaaa gtttgatttg
     1441 ccgttgttca tttttttcaa gcaaactgaa aagttccaag tccactcctt caagcatttc
     1501 tgattttaac agcagaagtt tccttctcat ccttgaaaaa gaggatctgt gacagttatc
     1561 acagatccat acaaattcta atcacttagc tggttggccc agctgtcagt tcccatgtga
     1621 ccatgccttg atacgttgcg ccaggttgag cattcgtact gctatttacc tctaagagta
     1681 aaccatcggt atcgggaaag tcaacgagaa cctctccttt agctgttcca tcactctcat
     1741 aaatcaacgt gttttgacct tgctgaatca attgctttga tccagaatga ttgaagtata
     1801 attttgttcc gcttaattct tgaccttgat cattcttaaa taaagaagtc aatgtacctg
     1861 tcagttgcca aggagacgtg cttggaagcc gagtatcccg cacatcaaaa gaaaaatcgc
     1921 cttttgattc ataataactt gtcttcaacg gtttggggag atcgttacca aatgtaaaat
     1981 catctggtac attaactaat gttaattctt gtttggggac aagaattgtt ttagcagatg
     2041 tttggacaac tgggttagga agcttagcac catctgctaa tgtaatattg ctggaaagta
     2101 cagctgcctt tgtcagtatg ctgacggatt gtaaagaagt atctacagta tttaattgat
     2161 agttgtaagt aagatgaatg gtatctccta ttttgctcaa tagatctgct gggacagaaa
     2221 ctccttgttg aatgccggta tctgcgatag ttgtaccatt taattttaag gaaccattga
     2281 tataagtagt attttcagga agtgagatcg tgattttttt gtcggttatc gcatccccag
     2341 attttgttaa cgtgaatgtc acattttctt gaatcgtatc tcctgataga gcagacaggg
     2401 gatctcctgt ctcaggttgt ctgctaaggt tttttagctg actatctgca ctcacagatg
     2461 gaaaattagc cactgttatt tgaggaagag tggtgattcc agcttgttca gactgccatt
     2521 tgtacgcaaa agacggatac atgttagtaa gtacatcgtc caccaagcga taatcaaaat
     2581 aatattgccc tgaagccaat gcaggtagtg tagaagtagc tgtatttaca cccccgttat
     2641 ttgattggat cgtttggaaa agttgatctg tccatcctgt cgctaatttt tgggttcctt
     2701 tcgaataaag cctgtaatgg atcgaaccct tttttagttc agttgctgac caattggccg
     2761 tgacttggta cgatgcagaa gaaaggagct ttccccactg actatcggct gttaagtttg
     2821 ttggtaaaac cgttccgtct agcttgtact gctccaatac ctttaaagca acaggagaaa
     2881 gcaatccgcc ttgcgcatct ttcccactgt acacgatatt ggctgtctga ttcaatccac
     2941 ttgtgcttgc tggagtatga gtcagtattg ctccttgtgt aacgtttttt cctgtaaaat
     3001 agttgactac gcgatcaaag cgactaaatg gcaactgatc aaaacgtcct tcagtcagcc
     3061 ccatcgtcaa tgtccgacta ttggtagagc ctggaaggtt ctggttattt ccatccacgt
     3121 attctgtggt atcagcaaat gtattatatt ttcctgttga atcacttggt gagatgtaac
     3181 tattccacgt atttatctct gcacttgcag aaaatgcata tgctcctgga ttcaagtttc
     3241 cgccagttaa tttaggataa aatctacctg cagctggagc taaaatcgaa ttgaacatac
     3301 gatcttggat aatattattc gaatcataaa aatcaacaga aaaaacggcc tttttagaca
     3361 tagaaggttg taatttaccc ttggtcaaaa ttttgtttgg actcgtatca tatttatctc
     3421 cgttttctgt catcttcgcg acattagctg taacatcaaa ttgaagcggg atatcgtcca
     3481 cgttgaattc gcctcgcgta ataatagcaa taatatctgt caatagagta tttgtatccc
     3541 acgaccccat cccaaaacgc aaggtatggc ttcctgctga taataaactt ccgctagtaa
     3601 ccttgatggg ggcaccggca atatacaagt aggcgttgtt ccagtcaatt gcttttaata
     3661 catcactgct tgatacatgt tccggcaaat tgatgatcgc cacaaatgca aatccttgtg
     3721 cagtgatatt caccaaatca agtacatttg ttagtttcac atggctttcc caatgaaaac
     3781 ggaccgtgcc acctttccaa ggatcatttg aaccatcgtt caaataagta gcagtcaatt
     3841 taggcaattg gttagcccca gttagttgga caagcttccc gccattgact gcactacgtc
     3901 caccatttgg aggtacgata ttttcatacg tgtatggatc ataagaaatg gcaggaggcg
     3961 ttgctccaac agcttctgcc gaaggtgaaa agataaatat acttaaaaca aaaagcgaag
     4021 taaaaaagaa ggagcgaaaa aatgaaaatt tattttgtag caacatgttc atcctccttt
     4081 tcctttcttc tccataacaa caaccacgca agaagccata attctatacc aatgatcaaa
     4141 taaagaaaac ggatcttttg ttcattcgtc tccgggaata cgccatgttg attagattct
     4201 ttataaatcg gtagctgtgt ctgctgtttt gatgcgccat tgactgaacc acttggatgc
     4261 ggaattggac ttagatcata aaatgtaatc gtacctgaac ttttggtatc tgcttggact
     4321 ggctcttgcc agctgaagaa cagcaaactt gcaataatcc ctcccaataa gatcgatgtt
     4381 ttcaacgaaa tcacctcatc atgttgtttc tccttttttc tttttcttgt ggacccacaa
     4441 aaacagcaaa atcaaccata acactagaac tgcagcaacc aatcctgcat aaagccatgg
     4501 gaaagattgt tcttgtactg caaaaacgga attttcattt actttttgtg ctttttcttt
     4561 tttgatcgta aagttttgtg taaatcgcca ttcattactg tcgcctgatt ttgctatgat
     4621 ttctgcgcgg taatcgccgg cttttgcttt atcaccagct aaatcaagat tcaagtgaaa
     4681 attcgaattt ggtgcaacta aaaatgcatt agacgtattt tcaatataaa gctgattttc
     4741 ataaaagatc ttgctcgtaa atatcaaatt gctgataatc ctaggctgag gattttggaa
     4801 acgaagctga acagttggct ttgcgttgac ctcgtccaaa tctcctgata aaagtttcag
     4861 atccggttct atcgtctctt gactttcttg taaaacgact gcgagattat aagcaatacg
     4921 atttttgatt tgtgctcctt ctgtagcatt ttctgtttca gcttcttctt taggtgaaac
     4981 atgaataccc gctaatacac gtcccttaaa gctttttgct gggattttca cttctatagg
     5041 tacagttgtt tctgcatgtg ctgatacatt gatttccttt ttcgcaatga gcaaaacgtc
     5101 acggacatca aacggcaatg tctcatctaa cgttgggttt ttttgactat aatcgatcgt
     5161 tccaccatca ctcgttaccg ccggattgac agagacctca aatgttcgtt cttcatctga
     5221 agaattgctg ataattactt ctagtgtctg attttgttcc ggtgccacta ataaatcaaa
     5281 ataaccgatt gctttatcta tttggttctc tggaaatacc ggtttgattc caaagtctcc
     5341 tgctgaatcc tttgcttggc tgattgacgg aaaaatgaaa aatagactta aaatagaaaa
     5401 aaacgaaaca aacagtcgtt tactttgatt cattgtccac cacatccttt caacaacaac
     5461 tgcggtaaaa aatccttcac ctatagtatt ttcaccgcag tttgttgaat ttatttcata
     5521 ctctatgcta ctgggccagc cacgaggttc caagtcaaat cagccgtgaa tgttccagct
     5581 gctgctttcg gcactttcag tgtgatattt gctggatcat aaacagaaag ccatgttccc
     5641 agaccttgat cttttgctgc tgtaaatatt ggtgtcgctg cacttgcttt actcaaccca
     5701 gttacagttt gactagttgg tccagtggat tcgttatctg acgtactttt aacagtggat
     5761 gttccaaaat ctaattcagc gccttgcaaa acttgtgaac cgtttacaaa atctgaaacc
     5821 gaaactgtca cgttccaccc ttgtgcttgg ccatctgcac ctacacctcg acgatctgat
     5881 acttggagat aaggtgtatc gttttttgaa gcgtctactt gatacgtttt tgttccgctt
     5941 tcaatctcgt gtgtaccaaa tggcaattcg ggaactacat ccagtgttaa aggacctgtc
     6001 tggccagttg ctggattttc cggatctgct ggctctactg gttttgaagg atcagtaggg
     6061 ttaagaggct ccacggtatt tgttggttca gtaaaggtaa tatctccttt tgaagtcgct
     6121 tgaccctcag caaaagctgg tgttgccaag ccgcctagaa gaagtgttga aagtaataat
     6181 gtcccaatca tgttcttttt cataataaat cactcctttt tcttagtgac ctaagtatag
     6241 tagagacagt atgcaaaaaa tcctcatgaa ttcatccgct tacttgaaat tatgaccctt
     6301 tttgtataaa agagaaaaaa acaataaaat cgtttacatg aatattcttc cttttttatt
     6361 aa
//
LOCUS       DASHWW010000112         6286 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.115, whole genome shotgun sequence.
ACCESSION   DASHWW010000112 DASHWW010000000
VERSION     DASHWW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.115"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..177
                     /locus_tag="U2R64_002736"
     CDS             <1..177
                     /locus_tag="U2R64_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919485.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="U2R64_002737"
     CDS             190..690
                     /locus_tag="U2R64_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEM8919486.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="U2R64_002738"
     CDS             787..2634
                     /locus_tag="U2R64_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HEM8919487.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEDLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="U2R64_002739"
     CDS             2637..3533
                     /locus_tag="U2R64_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8919488.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="U2R64_002740"
     CDS             3583..3972
                     /locus_tag="U2R64_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8919489.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6286
                     /locus_tag="U2R64_002741"
     CDS             3959..>6286
                     /locus_tag="U2R64_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8919490.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2119 a          933 c         1347 g         1887 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg acttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccgg
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagaggcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaac
//
LOCUS       DASHWW010000113         6209 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.116, whole genome shotgun sequence.
ACCESSION   DASHWW010000113 DASHWW010000000
VERSION     DASHWW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.116"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            191..709
                     /locus_tag="U2R64_002742"
     CDS             191..709
                     /locus_tag="U2R64_002742"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEM8919491.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            837..1520
                     /locus_tag="U2R64_002743"
     CDS             837..1520
                     /locus_tag="U2R64_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEM8919492.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1829..1902
                     /locus_tag="U2R64_002744"
     tRNA            1829..1902
                     /locus_tag="U2R64_002744"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1863..1865,aa:Arg,seq:tct)
     gene            2061..2420
                     /locus_tag="U2R64_002745"
     CDS             2061..2420
                     /locus_tag="U2R64_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HEM8919493.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2543..4174
                     /locus_tag="U2R64_002746"
     CDS             2543..4174
                     /locus_tag="U2R64_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HEM8919494.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4236..4877)
                     /locus_tag="U2R64_002747"
     CDS             complement(4236..4877)
                     /locus_tag="U2R64_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEM8919495.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVPPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5063..5139
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5159..5467
                     /gene="rplU"
                     /locus_tag="U2R64_002748"
     CDS             5159..5467
                     /gene="rplU"
                     /locus_tag="U2R64_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEM8919496.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5494..5838
                     /locus_tag="U2R64_002749"
     CDS             5494..5838
                     /locus_tag="U2R64_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEM8919497.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5851..6144
                     /gene="rpmA"
                     /locus_tag="U2R64_002750"
     CDS             5851..6144
                     /gene="rpmA"
                     /locus_tag="U2R64_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEM8919498.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1956 a         1023 c         1314 g         1916 t
ORIGIN      
        1 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
       61 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
      121 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
      181 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
      241 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
      301 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
      361 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
      421 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
      481 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
      541 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
      601 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
      661 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
      721 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
      781 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
      841 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
      901 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
      961 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
     1021 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
     1081 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
     1141 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
     1201 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
     1261 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
     1321 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
     1381 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
     1441 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
     1501 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
     1561 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
     1621 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
     1681 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
     1741 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
     1801 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
     1861 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
     1921 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
     1981 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
     2041 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
     2101 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
     2161 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
     2221 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
     2281 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
     2341 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
     2401 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
     2461 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
     2521 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
     2581 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
     2641 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
     2701 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
     2761 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
     2821 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
     2881 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
     2941 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
     3001 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
     3061 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
     3121 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
     3181 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
     3241 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
     3301 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
     3361 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
     3421 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
     3481 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
     3541 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
     3601 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
     3661 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
     3721 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
     3781 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
     3841 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
     3901 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
     3961 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
     4021 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
     4081 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
     4141 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
     4201 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
     4261 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
     4321 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
     4381 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
     4441 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggcggg
     4501 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
     4561 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
     4621 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
     4681 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
     4741 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
     4801 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
     4861 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
     4921 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
     4981 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
     5041 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
     5101 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
     5161 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
     5221 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
     5281 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
     5341 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
     5401 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
     5461 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
     5521 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
     5581 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
     5641 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
     5701 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
     5761 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
     5821 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
     5881 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
     5941 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
     6001 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
     6061 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
     6121 tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt
     6181 ttgtcacagc cttttttgtt tataaaaat
//
LOCUS       DASHWW010000114         6134 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.117, whole genome shotgun sequence.
ACCESSION   DASHWW010000114 DASHWW010000000
VERSION     DASHWW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.117"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(207..1169)
                     /locus_tag="U2R64_002751"
     CDS             complement(207..1169)
                     /locus_tag="U2R64_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8919499.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="U2R64_002752"
     CDS             complement(1171..2610)
                     /locus_tag="U2R64_002752"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEM8919500.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="U2R64_002753"
     CDS             2795..4741
                     /locus_tag="U2R64_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEM8919501.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="U2R64_002754"
     CDS             5005..5877
                     /locus_tag="U2R64_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8919502.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1946 a         1054 c         1084 g         2050 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttct
//
LOCUS       DASHWW010000115         5877 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.118, whole genome shotgun sequence.
ACCESSION   DASHWW010000115 DASHWW010000000
VERSION     DASHWW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.118"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            641..1375
                     /locus_tag="U2R64_002755"
     CDS             641..1375
                     /locus_tag="U2R64_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8919503.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="U2R64_002756"
     CDS             1391..2560
                     /locus_tag="U2R64_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8919504.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="U2R64_002757"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="U2R64_002757"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEM8919505.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYAEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="U2R64_002758"
     CDS             3650..4576
                     /locus_tag="U2R64_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEM8919506.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="U2R64_002759"
     CDS             4595..5845
                     /locus_tag="U2R64_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8919507.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          956 c         1203 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacaac aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgcagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DASHWW010000116         5821 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.119, whole genome shotgun sequence.
ACCESSION   DASHWW010000116 DASHWW010000000
VERSION     DASHWW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.119"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(126..772)
                     /locus_tag="U2R64_002760"
                     /pseudo
     CDS             complement(126..772)
                     /locus_tag="U2R64_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(1180..1683)
                     /locus_tag="U2R64_002761"
     CDS             complement(1180..1683)
                     /locus_tag="U2R64_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8919508.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1806..2570)
                     /locus_tag="U2R64_002762"
     CDS             complement(1806..2570)
                     /locus_tag="U2R64_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEM8919509.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2678..2953
                     /locus_tag="U2R64_002763"
     CDS             2678..2953
                     /locus_tag="U2R64_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEM8919510.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3391..4341
                     /gene="yidC"
                     /locus_tag="U2R64_002764"
     CDS             3391..4341
                     /gene="yidC"
                     /locus_tag="U2R64_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEM8919511.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4520..4720)
                     /locus_tag="U2R64_002765"
     CDS             complement(4520..4720)
                     /locus_tag="U2R64_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919512.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
     gene            5525..>5821
                     /locus_tag="U2R64_002766"
     CDS             5525..>5821
                     /locus_tag="U2R64_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919513.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         1743 a         1197 c         1017 g         1864 t
ORIGIN      
        1 aaaggggctg tccccagact ttagtaggcg tcattagcta tctttcgtta gcatttaaag
       61 gcgaacacca tcacctattc acttccatta aaagatagca tatttttctg taaaaaacaa
      121 taaaattatc gttctttctt tacacgttca gcaaattcat agaaaggagc caatttcgtt
      181 aactgttgat tacattggtc actatcatga caaatataat tccccttttt cgtatacgtg
      241 ccatcagaac ctgctttcgt tgtagaaaga aaaagcgaaa cattcgatgt tttctgacag
      301 attgcacaga ttcccttatt tatcgttggt gataaagtac cgctaatccc ttttaatttt
      361 tcatcttcgt aatagaccat gaattttttc tgcgtacctg gatcattcca gccgatgtac
      421 gtatgttctt gcaagtcgat ttcattccaa gctggttgtt tgagtttttt cacttttcgg
      481 aataatttct cgatttgtgg tttgctaggc tgcataaacg gctgaacgat ttgcttcagc
      541 tcctccaatg ctctttctgc ttgcgctttt gtcagtttta cgtctaaaac tgtcgttaaa
      601 aatgtatcga ttctggcagt tcgtgatcta atatgtctcg aatcttttca gctgctagtg
      661 cctgaactgt ttgtaccgtt tttggatcat tgacagatga gtacgcattt aataactgtt
      721 ctacttctct tattataaaa aaatattggt atggttttat tgtttgttcc atgattttaa
      781 agtcctttct tctaaccaaa gtgcatactt tgtagaaaaa agtgatcttc tgcaaagtat
      841 gtgttacctg aagatcccgg actcttttaa ataagatacg ttttgcatct tatcatcacc
      901 ccctttaatg cttattattc tatgtacatg attcattcga taaataaaag taaaccgtat
      961 cttgaacaga tagtcaactg caaacagaaa aaaggactgt gacaaaagtc gtgtcaaagt
     1021 cccttgtttc gaatgaatgg tgttcaaaag ctggcatctg cggtaataag ccgaaacttc
     1081 acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc
     1141 tgtcacaacc tcaatatggt ctattattgg ttttatctat taaatcgagg attctttccc
     1201 aaagtaacgt tgccatctct tacgcatact tgctgacata ggctgagcgg cttctttgac
     1261 tgcgcagtat ttgtctacga atgttacgat atatccttct ttgtacttag gcggtgcaat
     1321 cgttgcgccc cacatgtgct tcaaaatgat atctcgctca agatccgaca attcggtgat
     1381 cttttctgca ttctttacag caattcttgg atggatatac gcatgtgtgc cttcatcaaa
     1441 tttcgtcgta cgccaatcat agtagaacag atcatgcaaa agtccagcac gcgctgttgc
     1501 tttagcattg ccaccccatt tttttgcgag cagataacta tagtaagaaa cactgatgga
     1561 atgctccaaa cgagtggaat gaacatgctg tgtgtaattc gctaattttt tcactgcttc
     1621 tgtttctaaa agatcttcta cataagacat atattcttcg tcttcacgcc atttttctgt
     1681 cataattatc gatctgccac ctttttgaat ttcattttct tctgaaattg atctaagtat
     1741 accaccagtg ttcggattat tctagtcgcc ttggataaaa tagccaaagc ttaatagttc
     1801 cttaatcata aagaaaaatg ataaagaaca atccctgccg caaccccaac attcaacgat
     1861 tccgcatttc ctttcatcgg gatatatacg ttctgatcag tcaaagacaa gatttcctga
     1921 cttaccccct gaccttcgtt ccccatgatt attgcgaagt tatctgattt ttctactttg
     1981 tctaatgcgt gtgcttcttc atttaattct gtgccataca ctgtaaaccc tttgtctttc
     2041 attaaaggaa tcacttctgt caaatctttt tgcaacacag gcaaatgata attgcttccc
     2101 tgcatgctgc gcagcacctt tgtactataa atatctgccg ttcctttgcc taataaaaca
     2161 ccagccatat caaatgcatc tgccgtacgg atcatcgtcc ctacatttcc aggatcttgt
     2221 acattatcta acaacagcca tcctcctgaa aaatctggcg tgccttcagc cgttaacgcc
     2281 atcactgcta agattccttg tggtgtaggt agatccgata cagcatccat gacctcatcc
     2341 gaaactagaa aagtagaaat ctctttgttt gcggccagcc agtctcccca ttctttcatg
     2401 cctcgctgtg tcacaaaaag ttcttttatt tctgcatcag acgacgcagc ttcttcaatc
     2461 agatggaacc cttccaaaag atattcttcc ttttcttccc gatatttctt tttatgtagt
     2521 ttttttaatt ctttgattct tggatttttt gctgattgga tctctttcac attcctcacc
     2581 tccccatgat tatatcatgg aataggtgct tgagcttgtt tcatcctaaa aaaatcggta
     2641 tcattaattt ataaaatagg aaagaaaggt gacgaacatg cgcaaagtta aaatgaacgt
     2701 ccaaggacgc gtccaaggcg taggatttcg ctacatgacc aagatggtcg ctgatcaact
     2761 aggcgtgact ggaacggtaa aaaacgaaga tgacggctca gtcacgatcg aagcaatcgg
     2821 caatgacgac atcatccaga aatttattga agaagtcaag aaatctccga gcccaagtgg
     2881 acgagtgcag tatgtggatg tccaagaaga cccgatgatt gaggaacgaa agaaatttga
     2941 tgtggtggga taaggttgtg aaaaagctgg tctgcatcaa gcattaagga caggttgtga
     3001 aaaatagctc tccatatttt tcaacaggct ggacttaatg ccgtagatgc aagcttttga
     3061 acaccgtcga taaggttatt cttgaggcgc tttgcctcaa aaattaagga cagcagtgaa
     3121 aaagctgatc tatcacttgc agtgagttca tttgactccg ctttttcggg cagaaaaaaa
     3181 gtttttagtt tattaaagta agaaagaaac acttggaatc attctacttt ttcctagtat
     3241 ttctttcttg attttttgtc tttttttcaa aatttttcgc tacgtaaaag aacgaatatt
     3301 tatatgaaat ttctatgaag ttgattgaat tccatgcgct tttttagtat agttaagttt
     3361 gtgtaaaaat tatagaagag gaagtattct atgaataaat ggaaaaactg gttattggga
     3421 tccggacttg tcagtatcct gctcttttta tctggctgtg tgcggatgga ttcaaacgga
     3481 aaccctgaca cttcgggaat cgtttatcga gtactcgtcc atcctatggg ccaagcgatt
     3541 acatatctag ttgaaaattt caattggtct tatggctggg cagttattgc aatgactgtg
     3601 atcgtccgta tcatcatctt gccactaggt attagtcaat cgaaaaaaac aatgatccaa
     3661 tctgaaaaaa tgcaagcgtt aaaaccacaa gttgaagcag cccaacaaaa attgaaagct
     3721 gcaacaacac gtgaagaaca aatggcagca caagcagaaa tgcagcaagt ataccgcgaa
     3781 aacggattga gtatgaccgg cggaatcggc tgtctgcctc tattgatcca aatgccgatc
     3841 ttctctgcct tgtactttac ggcacgttat acagaaggta tccgggaatc atctttctac
     3901 ggcatcgatt taggctcacc aagtatggta cttgttgcca ttgcaggggt cgcttatctg
     3961 cttcaaggat acatctcaac gatcggtatt cctgaagaac agaaaaagac gatgcgtacg
     4021 atgctgatcg tctctcctgc tatgatcgtc ttcatgtcga tcagtgcgcc agccggtgtt
     4081 acactttact gggtagtcgg tggtgtgttc agctgtctgc aaacattcat cacaaacgtt
     4141 atgatgaaac cacgtttgaa agcacaagtg gcagaagagt tgaaacaaaa cccaccaaaa
     4201 caagtcgtca ctccaagaat tgatgtgaca gaatcagcta aaccagctga cagcaaacaa
     4261 gcaaccaaac aaatcaagca acccaaaaac agtacaaaca ataaaggccg caacgcagga
     4321 aagcagcaga agcggaagta gatagtaaat aagagtgtaa taaaaattca ttaacagttt
     4381 tagcaattaa aaatatcgac caagattttt gaaaaagaaa tctggtcgat atttttattt
     4441 aagtgaatgt ttaatttgaa tcatcgattg atcgctatct aattgcagca gcatcttttt
     4501 atgaagaaac aactttttct tatctatcaa cgtagacagg tgttgctgtt tcttctaata
     4561 gtgtacttaa ttccttaata ttttgttttc cttcttctaa catccaacta ctcgcttttt
     4621 cttcgccttc ggtaacaaaa ggcgccactc ccttcgccca tgttgctcgc ccacataaga
     4681 caccattctc cataaaggac aacgcggaga taccacccat ctaaataaca tccataaacc
     4741 tttctagtag aagaatagtg atagtatcca tccctttttc tactgggaat acaattacac
     4801 gattcaaagc ttgatacaca acatttccct tcttataaac cgctattgta accgaattgt
     4861 tttgaatcac ctttttggga tagaaactgg ctcctttccg caacttctta aatgttggtt
     4921 tcttttatac tttctttgta gcaactacaa atttcttcaa atctctaaat gtttgcataa
     4981 caaccgcctt tctgactttt actcaggatg gtatttaaaa atcagcaaaa taaggcttct
     5041 ctccatcttt tttatttcct agctgcttta aagacactct tgctgttttt taatctctat
     5101 caagggggct ctgaatctat tttgatgaac ttatcttatt aatttctcaa atgagctgtc
     5161 agacacaact gtattttttc aatctcatac cggacaacta tgccagctta aaaaaatttc
     5221 ctctggcaaa acttctttat tgaaaaatga caatgaaaaa agaccattct ttttgttgaa
     5281 tgctcattgt gtaaacatat ttcctgcgac tgctcttcga accattctca gtgcaatccc
     5341 taatttatct attaaatctt cttttagttc ctcatctttc atattcaaaa tttcctttgt
     5401 atgttacaca agtttgttct ctaaataacg cgaattgtaa aattaagtta gaaaaataaa
     5461 aaggcattta tggtacactc aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc
     5521 ataaatgacc tacaaacatc ttaccataga cgaactgaca atgatagaat catattatct
     5581 tcaacataat aagccggttg aaatcgctaa ccgaatggga cgtgctatac aaactattta
     5641 taatgtagtc aataagttca agcaaggtaa gactgctctt gattattggc accagtataa
     5701 agaaaataag aaaaaatgtg gtagaaaagt cattcaatta cctgctcatg aagtagatta
     5761 cattaaagag aaagtcactc ttggttggac gcctgacgtc attatcgggc gaaaagaaag
     5821 g
//
LOCUS       DASHWW010000117         5467 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.121, whole genome shotgun sequence.
ACCESSION   DASHWW010000117 DASHWW010000000
VERSION     DASHWW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.121"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            119..1108
                     /locus_tag="U2R64_002767"
     CDS             119..1108
                     /locus_tag="U2R64_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8919514.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1090..1551
                     /locus_tag="U2R64_002768"
     CDS             1090..1551
                     /locus_tag="U2R64_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEM8919515.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1601..2065
                     /locus_tag="U2R64_002769"
     CDS             1601..2065
                     /locus_tag="U2R64_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8919516.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2079..2828
                     /locus_tag="U2R64_002770"
     CDS             2079..2828
                     /locus_tag="U2R64_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8919517.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2828..3658
                     /locus_tag="U2R64_002771"
     CDS             2828..3658
                     /locus_tag="U2R64_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8919518.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3658..4305
                     /locus_tag="U2R64_002772"
     CDS             3658..4305
                     /locus_tag="U2R64_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8919519.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4403..5179)
                     /locus_tag="U2R64_002773"
     CDS             complement(4403..5179)
                     /locus_tag="U2R64_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8919520.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5261..5404
                     /locus_tag="U2R64_002774"
                     /pseudo
     CDS             5261..5404
                     /locus_tag="U2R64_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1872 a          740 c          973 g         1882 t
ORIGIN      
        1 cattttatta tataaaattg ttataaaaaa ttttttttga aaaatagtat tgcaaaataa
       61 agcaatttca tagataatag gtatcgtaaa gttatataac tttataatac ctattagagt
      121 gagggataaa gaaatgagac aactacacaa agaacagatt gaaacagcaa tggcagcgtt
      181 aaaggaaaag acaattgatc atgtatattt tacagcatgt gggggttcac aagccgtttt
      241 aatggctggt caatatctat ttgataaaga attaactgta ccttgtcatg tttatactgc
      301 taacgaattt aactatgcta taccaaaagg attatctgaa aattctttag ttatcacttg
      361 ttcccattct ggcacaacac cagaaactgt agaagcaaca aaaaaagcaa gagaatttgg
      421 agcaatgact atttgtttat ctaatgaaga aggatctcct ctatgggaag cagctgaata
      481 tcctgttcac tatgattggg gtaaagatgt tgatgctagt gatttaaata aaggaattct
      541 ttatggttta ttatttaata ttttacttgt tttagatggc tctaaaaaat gggaaacttg
      601 cttgaatgaa tttgataagt taaatgatct tgttattgct gaaaagagca aatttgaaat
      661 aactgctaaa gaatggggta aaaaccaaaa acgagataaa attatttaca caattggtag
      721 cggtattaat tacggagaaa tttactccac agcagcttgc tggttcatgg aaatgcaatg
      781 gattaattct aatgctattc attctgggga atttttccat ggtccttttg aaatcactga
      841 ttatgatgta ccattcatct tagtgaaaag tattggagat acaagatttt tagatcaacg
      901 ggtagaagac ttcactaaaa aattcagtaa taaattaatg gttttagacc aagctgattt
      961 tgacttagaa tctatagata gtgtagcgaa agaatatatt gcagctgtac ttagtggcgt
     1021 tgttattcgc caaatggtag aagcgattgc ttttgaaaga ggccattcct tagatgttag
     1081 acgctatatg tggcaaatga aatattaatt aataggaggt tgcaaaagat ggcaaatcaa
     1141 ttatttcaca ttgtgattac aacacattct accctttgtg agggttattt aaaggcaaca
     1201 aaattaattt taatgaatga cgccacaggt attagtgctg ttccatttaa agaaaatact
     1261 agtccagatg attttgagga gagtatgaaa gaaataatta gtcagcatca tttgcaacct
     1321 ctaattattt taacggattt aattggagga acacctaata atgtttctat taaacagttg
     1381 aacaacaata gaattcaaat tattgctggg attaatttac ctcttttact ggagttatta
     1441 atggcccagt cagctggtaa atctatagaa gaaatagatt ttaaggaatt actgaataac
     1501 tctcaaaaaa gtatggttca tattaattcg cttttaaaag atgtcagtta aggtggcaat
     1561 ttctattcta taaattttaa aaattgaagg aggaaataga atgattaaat tagtgcgtgt
     1621 agaccacaga ttacttcatg gacaagtaat attttcttgg actaaacagt atgatattaa
     1681 ccatattatt gtggctgata acaaagttcc aggagatcca atgtctgtga tggctttgac
     1741 aattgctaaa cctgctgatt gcaaattaga cattgttaaa attagtgatg ttaaagggat
     1801 tatggaaaca tccccaaatg ataattacat gattttaatt aaaggaccta aggaagcttt
     1861 tgaattagtt caaaatttac cagaaattaa agaaattaat tttggcggtg tgtctaagaa
     1921 aagcgagtcc aaacaatatg gaaaggcagt ctttttaact cctgaagaat tagaagccac
     1981 aaaaaaaatt cttgatcaag aagtgaaaat atttgtgcaa caagtcccat cttcaagtat
     2041 tgaaaatgta gattttagta agtaaggggg gaaaataaat gttattaaaa gccattttat
     2101 taggtttagt tggtgtggta gctgttattg actccaggtt aattggtcga caaaatattg
     2161 gtagaccact aattttgagt acacttgccg gacttgtgct aggtgacttg catacaggga
     2221 ttgttcttgg ggcatcttta gaattaattt ctatgggatt cgtctcaatt ggggcggctg
     2281 gacctcctaa tatgcaactt ggtagtatta ttgccactgc ttttgcaatt ttaactaata
     2341 gtagtacaga aacagcctta acaatagcta tcccagtggc tgtagctggt gaatttatga
     2401 gtattatcat gcgtatgata attgctcaat ttggacatgc tgcagataaa gccattgaaa
     2461 ataataaatt tagaaaagct caaattattc atatttattg gtcatttatt tttaatgctt
     2521 ttgtttactt tattccaatc tttttaacag tatattttgg tgctgacgtt gtggcagatt
     2581 tagtagataa aattccagaa atgattacag acgccttgac tgtctctgga aatatgcttt
     2641 ccgcattagg gtttgcaatg ctattaagca caatgttgag taaaaaatta tatccttact
     2701 ttatttttgg attctttatt gttgcctatt caggtctttc actaattggc gtgacaattt
     2761 ttgcagctct gattgccttt gtaatggatc aagttaaata tggaaaaaga gaagaggcgc
     2821 atggttaatg gaaaatagta cagaaaaaaa acgtttaatc acaaaaaaag atcttcataa
     2881 gatgtgtctt cgttcatgga caatcatgtg ttcgtggaat tatgaaagac aaatgcatat
     2941 gggatttatg tatgggatgg cgccaatttt aaataaagtt tataaaaatg atgaagagaa
     3001 aaaaagagaa gcttatactc gtcatatggc attttttaac tgtacgcctc aaatgactcc
     3061 atttattatg ggactttgtg cttctatgga agaacaaaat gctcaagcag aagaaggaaa
     3121 ctttaatact gaatctatct ccatgattaa aaccagttta atgggtcctt ttgctggaat
     3181 tggtgattca tttttccaag gtactttaag aattattaca tttgggattg gattgtcttt
     3241 tgctaagcaa ggtagtattt taggaccgat tttagctgtt ggcctttttg ctataccttc
     3301 tattttagct gttttttacg gcggtaaatt aggatatgag tctggcaata aataccttac
     3361 taaattgtat caagaaggtc ttatggatcg agtaatgcaa tttgcttcta tcattggttt
     3421 ggctgtagta ggtggaatgg tggctagcat ggtgccaatt gtcacccctt taaaattcac
     3481 tacaggggga acagaacttg ttttacaaga cttacttgat tccattattc ctggattatt
     3541 accacttgta tgtactttgg gaatatataa attgattaag aaaaatgtta gtacaaatat
     3601 gctcttatta ggttgtattt tggcagggtt tgttttaagt ataataggta tcttataatg
     3661 attaaggctc taatttttga tatggacgga gttttaattg atagcgagat tatgtatcaa
     3721 aagtgggtat ttaatttttt aaaacaagaa aatttaagct atcctttgta ttcttatcaa
     3781 aaaaagattg gaactacagc aagtattttt gatgatatag aaaagtacaa tgagggatgt
     3841 aacagtttag aattgaaggg aaaatttact aaatattgga aatcgcaaaa gattgattac
     3901 ttggatattt ttcctaatat actaattgaa cagcttgaat ggttaaaaaa gaaaaaaata
     3961 aaaatggcaa ttgcttcttc cagtccaatg gatactataa atgaagttgt taccacttgt
     4021 aaaatagagt catattttga ttgtttaatt agcggaagag atttgccaga aagtaaacct
     4081 aatcctacta tattccttaa agcttcagaa cagctcagaa ttccagttga agaatgtctg
     4141 gtgatagaag attcttataa tggtataaaa gctggtaaaa gagcaaatat gaaggttctt
     4201 gcaattaaag ataaacgttt ttctcaagat gtaagtctag cagatgatgt tatttacgat
     4261 attaaatatc tgcgacaaga agtacaggtg aaatttggaa tataaataag ttttttgatg
     4321 tatttagaga atattagtaa aaataaaaat catgcccaaa tctaatcaaa attgattgct
     4381 ttgggtatga tttcttttaa tatcaatcta ttactttagg atctgaatca tttttatgca
     4441 ccgtatctaa agtgatattt tctgtgactt caataacata actaattcta tcacaacgaa
     4501 ctgtggattg agaataatga aatggttgat tatttttatc tttgccaacc ttttctaaaa
     4561 taaatagcgg atctcctact atacattgca ataagtcgga aagctcaggt gttgcagata
     4621 aaccgtttat ttccataata gagctcgtag ctttgacatc atagtcatct tctagaagtt
     4681 tatataatga agtatattgg ctaccttttt caaataaagt tggaaatttt tcttctgatg
     4741 cgaaaaaatt atcaattccc atcggggcac cgtcttccca cattaaacgt ttaatattgt
     4801 aaactctatc agttacattg atttgtaatt tattagctaa aaactcatca gcctttataa
     4861 ttttagaatg taaaacagta tatctaattt tatgtcctcg ggtagaaaga gaatcgctaa
     4921 atccatgaac tccagctaat tttaaacttt cttttttttg agttacaaag gtccctttcc
     4981 cccttaatcg ttcaactgtt ccactttctg ttaaaagttt aaaagctttt cgaatggtaa
     5041 tcttacttac tccataaatt ttacataatt cttcttctgt aggtaattgc tctcctggaa
     5101 gatatttttt ttcacgaata tcgttacgta tagaagcttc tacttgtaga tataatggtc
     5161 tattatcttg aaaattcata gtacactccc taaaaagtta tacttcatta tatcacaatt
     5221 tattaaaata aaagattaag atataaatat aaatgaacta gtctttgact aaccaatgcc
     5281 cgcttttgaa agaaaacaaa ttcattctgt tttaagtaaa aatccttatg ttaccactca
     5341 ttctgaaggg gatgagcctt atcgctactt ggttgtggaa ccaagcgata agacaatttt
     5401 ataaattcaa tattaattaa aataaaaaca aacaaagtag attattttac tttgtttgtt
     5461 tttttat
//
LOCUS       DASHWW010000118         4838 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.122, whole genome shotgun sequence.
ACCESSION   DASHWW010000118 DASHWW010000000
VERSION     DASHWW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.122"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..508)
                     /locus_tag="U2R64_002775"
     CDS             complement(<1..508)
                     /locus_tag="U2R64_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HEM8919521.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLL"
     gene            complement(695..1345)
                     /locus_tag="U2R64_002776"
     CDS             complement(695..1345)
                     /locus_tag="U2R64_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919522.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1888..2823)
                     /gene="whiA"
                     /locus_tag="U2R64_002777"
     CDS             complement(1888..2823)
                     /gene="whiA"
                     /locus_tag="U2R64_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEM8919523.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2857..3855)
                     /locus_tag="U2R64_002778"
     CDS             complement(2857..3855)
                     /locus_tag="U2R64_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEM8919524.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3852..4736)
                     /gene="rapZ"
                     /locus_tag="U2R64_002779"
     CDS             complement(3852..4736)
                     /gene="rapZ"
                     /locus_tag="U2R64_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEM8919525.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
BASE COUNT         1456 a         1041 c          754 g         1587 t
ORIGIN      
        1 tcaacaacct tgatccttct tttatagatt caggaaacag tataatttta gtactagata
       61 aattgtttac accgattagt gttaaaatat ctttattctt cttgctaaca taacccttta
      121 tgcacaaaag aacagctata cttaaagtaa caaataaata acgtattcca atagaaaaat
      181 cactataaat actctctagc ataggaccga caattgaaga agtcactact gcaaatgctg
      241 gacctatcca agcaacatta gaatgttctt tctctctttt cctttgtaaa tctttgttga
      301 gtattaatct atttatttct tctgcaggca agttaatttt cataacctta tgggggatta
      361 tccaattaaa aatcggaaaa aggtagcctc cccaaaaagt atagtgatct gtgtcaatca
      421 gataataacc tgattttgat tccagaataa catatctcaa agccgaacga aaatttttca
      481 tgaatatcca taatctcact gtttccacac ctaattcctc caattccaat taaatggatt
      541 tatagcatca ccaattatgt taactgcctg accaacctca ttgataaaat tggcaccact
      601 atcccatgct tcaacaatgc tatatatcta tcaaacaaaa aatggaaaac taaatactcg
      661 cgcacataaa ttttacattc tgttttttat aagactaata ataatcattg aaaaaatttc
      721 ttatcggtgg cgcatattcc caattgatta atgtgatccc atattctgca agtattttac
      781 gagcttcttc taagtcatag tgagaaaaat gcataaaacc tgcaatacga tcacggactg
      841 tgagctgtgg cttgcttcca ccatcattca taaaatatcc agcagagcca ctacttaaag
      901 tgattgttac atcttcactt tctattatta agaattcata atgaaatgct ttcaactctc
      961 cactattatt taaaagtttt atactccaac ttcgtctagg ttgagttgtc acattccctc
     1021 taaaacttcc tataaattct gcaatcaccg tatcttcaat caaaattctt tcctcatcta
     1081 tttcatattc aagactaaac ggaaattctc catatgtaat ctctggcaat ggtggtgctg
     1141 tagttctcca aataaataca ataactgtga atagaaaaaa tccaacgatc gatataaatg
     1201 ttatgagacc tgctcgaagt aaaacccgat ataataaaaa tgctgtattt cgctttgcta
     1261 tatctagaaa aataaaaagt actgcaatca taatgatagt aaaagttgta aaaaagcaca
     1321 ttttttgccc tccctttata aacatcgatt ctcaaattct aaaccaaatc ttgatagttc
     1381 aagttcaggt ataacgtata ccaaccatac atcccaatta ctatttatga acttatgatt
     1441 atcactgaat aaatcactcc atccccttgt taaaacttct acattaatta cacctggttg
     1501 ttttcgacta gctaatccaa tgaacttatc aaccatcctt atccaccaac cacgagaatc
     1561 ttgaccagaa gtaagaaaaa cagttctcaa ggttgatcga gcagttcctt ccagttttta
     1621 attaatctcc agttatagat aaatacttga tcctatctat atcaggactt ctatattaag
     1681 caaaagttta tgtataaaac taaaatcttc attcagttgt ctccccgctt tttatacgat
     1741 tgtattaaaa aacaatagaa gcctttcaac attatgttac tccagtaaag ttggaattat
     1801 agtttgacgg aagaaaagca agtatagctt ttaaaaaaaa ctgatacatt cgcatctcct
     1861 gcttcatgta tcagtttttt ctttggatta aactgcttct tcacgcagtt tttccgcaaa
     1921 ttcatttatt ttgcgaattc ggtgattaat tcccgatttt gatattgcac ctgagggaat
     1981 catttcccct aattctttca agctgacctc tggatgttga agccgaagtt ctgcgatttc
     2041 ctgaagtttt tcaggaaggg catgtagacc gacctttgct tcgatcaatt cgatgttttc
     2101 gatttgttta gaagccgcat caatcgtctt gttcagattt gctgtctcac aattgactag
     2161 acgattgacc gaatttctca tatcccgtac gattcgaaca tcttcaaatc ggagcattga
     2221 gttggttgca ccaatcaatg ttaagaaatc agcaattttt tctgctcctt ttaaatacga
     2281 aatatagcca ttgcgccgtt caagcgttcg agcatgtaga ccgtaataat ttaacatatc
     2341 gcaaatgtct tggttatgct gttcataaat agaaaatatt tccaaatgat aacgactcgt
     2401 ttccggatta ttgactgaac ctgaggccat aaaagcacca cgtaagtaag aacgcatttt
     2461 ttgcgaattt cccataatct cgtccgaaac gtgtccattg aacatcatac catccatgat
     2521 atcaagatcc atcaacacat cttttgtgcc ttgcttcaac cggacgatat agacattgtt
     2581 cttttttaat ttcatttttt tacgaacgag tagctcactt cgtacctgat aatgatcttt
     2641 caaaagagaa tagatacgtc tggcaattgc agcattttct gtttggacgt tcaaaataaa
     2701 ctgctggttc acaataccta aagagccgtt cattcgcagc aaagcagcta attccgcttt
     2761 cgcatgttct cgatgaactt ccaaaccagt tagttctttc ttcacatctg cagcaaatga
     2821 catcctattc tcctcctttc tccaacaata aattgcttaa tattttgaac cgaaaactaa
     2881 acggaacaat tcttctacta ctttgtctcc atcgtggaag acaccaccat ctttcaattc
     2941 taaaaagtcg gtggaaatca ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc
     3001 gacttgtact agatactcat catagatctc tgggtccata taatcttcag gcactttttc
     3061 cgtattgacc aatactgtat cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat
     3121 atgatcggca tctgtgaaat gttccgtttc ccctttttgg gtcatgatat tacagatata
     3181 gacggtttca gcagttgtct tgagcattgc ttcgccgatt tctggtatca ctaaatttgg
     3241 aaggatactg gtgaataaac ttccgggtcc caaaacgacc atgtcggcgt ccataattgc
     3301 tgaaacgact tttcgagccg ctttggcttc acttttatca tttgtgttgc agacatacac
     3361 acggtcaatg gttttacggt tgatcgcgat tttagattct cctactgcag tcgttccgtc
     3421 tttaaaaaca gcatgcaagg tcaaaggagt ttctgaagaa ggataaacat gtccatctac
     3481 atgcatcatt tttgctaata attgaatcgc ctcataagtg cttccccgca tctcggaaac
     3541 tgcggcaatg atcagattac cgatcgtatg attggctaaa aactgatctt cctttttgaa
     3601 acggtattgg aaaatatctt catagaattg tggcatatcc gataacgcca ctaagacatt
     3661 tctcaagtca ccaggaggag ccatagcgat cgattctctg attgcaccgc tgcttccacc
     3721 atcatctgca acagtcacta ctgctgtgat atctgctcct tgatttcgta aacttttcag
     3781 gataactggc agaccagtgc caccgccgac cactacgatc tttggttttc ttatccggta
     3841 ggttttcatt ttcacgaccg gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc
     3901 acattgactt tatagttttt ccctaaagca tttgccaaac gttcagtcaa tgccacagaa
     3961 cggtgttgac cgcctgtaca gccgattgca actgtcaagc tgctttttcc ttctttaatg
     4021 tatccaggca atacagtttc cagaagatcc aaaaatttat ggtagaatga ttgcgtttca
     4081 tcaaaggaca tcacataatc atagactggc tgatcttttc cggtcaatgg tcttagttcc
     4141 gggatataat gagggttggg caaaaaacgc acatccatca caatatccga atcgatcggc
     4201 aacccgtatt taaaaccaaa tgatacaaat tcgatccgaa atccttggtc tccctttgat
     4261 ttgaatgact cattgatttt ttcacgtaat tgtcgtggtg tcaatgttgt cgtatcaatg
     4321 atcacggaag cttgggcttt caagtcgtct agtatcgccc gttctttacg tatcccttca
     4381 gtgatcaaac cgtccatcgc cattggatgt gctcgtcttg tttctttgta gcgagccact
     4441 agttcttcgt ctgaagcatc taaaaataag atagaagtgt cgatgaagtt cgtattttcg
     4501 atttcgatca gcatgttttg gatttcttca aagaaggaac gagaacgcaa atccactcct
     4561 aaagccattt ttgtgacttt acctgattct ttgatcaatt cccagaattt tggaatcaat
     4621 cgaggcggca tattatcgat acaaaaatag cccatatctt caaaactttg gatagctact
     4681 gttttccctg caccactcat acctgttatg atgactaatt gcaaattatc tgtcatattt
     4741 acgaacccct ctcacattgt gcataataaa attatatcat cccgggcgta tcattaccag
     4801 ttttcttttt cttttacaaa aagatttgga ccaaatat
//
LOCUS       DASHWW010000119         4728 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.123, whole genome shotgun sequence.
ACCESSION   DASHWW010000119 DASHWW010000000
VERSION     DASHWW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.123"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(80..1888)
                     /gene="pepF"
                     /locus_tag="U2R64_002780"
     CDS             complement(80..1888)
                     /gene="pepF"
                     /locus_tag="U2R64_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEM8919526.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2064..3062)
                     /locus_tag="U2R64_002781"
     CDS             complement(2064..3062)
                     /locus_tag="U2R64_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEM8919527.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3288..3941)
                     /locus_tag="U2R64_002782"
     CDS             complement(3288..3941)
                     /locus_tag="U2R64_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEM8919528.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4273..4671)
                     /gene="spxA"
                     /locus_tag="U2R64_002783"
     CDS             complement(4273..4671)
                     /gene="spxA"
                     /locus_tag="U2R64_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEM8919529.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1388 a          994 c          741 g         1605 t
ORIGIN      
        1 aaaaaatacg tcgactccct tacaagagag ccgacgtatt tttttcgttt ctattcgaga
       61 aaatcaaaaa tagaaagcct tataaacgat cgatcaattc ttctaattca tttagacgtt
      121 gttcaaacat cgacattgca tcttcaatat atgcagcctg tgtcatatca actcctgctt
      181 ttttcattac ttccacagga taatcgctgt tacctgcttt taggtaagcc aagtagttct
      241 ctagtgcctc tggttcctgg tttagtattt tcttcgccag tgctgaagca gcagaaaagc
      301 cagtcgagta ttggaaaaca tagtaattat aataaaaatg cggtatccgt gaccattcga
      361 atttaatttc tgggtcttct tcgactgctg gaccataata ttttgcattc aatttaccat
      421 aactatcact taggtattca ctagtcaatg gcacaccttt ttcatcttcc gtatgcatga
      481 aatgctcgaa ttcagcgaat tgtgtctggc ggaaaactgt tcctttaaac ccatccaagt
      541 aatggttgag tacataagcc cgtacacgag ggtctttttc tgtttccaat aaatactccg
      601 ttaggatatt ttcattcgtt gtcgaagcaa tttctgctaa aaagatggag tagtcgccgt
      661 acacataagg ctggttcgaa cgagtgaaat aactatgaac actatgtccc atttcgtgga
      721 caagcgtaaa tagctgatcc agcgtatcat gccaattcaa taaaatatat ggatttgtgt
      781 catagcttcc cgaagaataa gcaccgcttc gtttcccttt attttcgaca acatcgatcc
      841 aacgttcaga gaatgctttt tctacgatgg ccatgtattc ttcacccatt ggtttcagtg
      901 cttctaaagc tttttctttt gcttcttcgt acgtaaaggt aattggagct tcccctaaga
      961 ccggtgtata aagatcatac atgtgcagtt tttccacttc taataaacgt ttccgtaatt
     1021 ccatgtatcg atgtaacaaa ggcaaatgct tgtttaccac gtctaccaaa gtatcgtata
     1081 cactttcagg aatatgatta ttgctcaaag acgcttctct ggcagagctg taattacgga
     1141 ctttcgcttt aaaattatgt ccttttatat gtgtgcctaa agtagaagca aatgtatttc
     1201 taaattgttc gtaaacactg tacaacccct taaatgctgc ttcgcgcacc cttcgatccg
     1261 tgctttctag caactgacca tacacgccat gagataattg gactatttca ccattttctc
     1321 cttcaatcgt tggaaaaact agatctgcat tattcaaaac agcaaatgta tcacttgaag
     1381 catcaaagat ttcacctgct ccagcaagaa gagattcctg ctcagcagat aagacatggg
     1441 ctcgattatc tactatttgc tggatataat ggcgatagac ttccaatttt ggttcttctt
     1501 tgaaatattg ccaaatctgg tcatctgaca attgcaatat ttctggttca aaccaggaaa
     1561 cggcttcact aactttcgaa aacagactgc ttgctcttgc ataaagcgct tggtaatctg
     1621 tatttccagt gtcttgatcg tttttaaggt gcgcatatac ataaatgact tcagtttggc
     1681 gataaaccct caatacgaat tcaatcgcat ttaaaaattg agaagcgcct tgatcaagtg
     1741 ttcctttgtg tttttcagat tgttttaact cttctgataa ttccaaatat ttctcatcaa
     1801 actcttggtc gcttgaaaag atcttggtca agtcccaagt taaattttca ggcaattctt
     1861 ctcgttttgg caactgcttt acttccatga aatccactcc ttttcttccc ttagctctat
     1921 ctatcaaaat agatcatagt ctaacatcca catgtcacag catctaactt ttctactcat
     1981 tcatgtgtct gcttccatca attttagcat aactaaatct tgttttacat agaaaaccga
     2041 ttcctagcct atttttatac ttactatttt ttcaaagaag acaagtgtat gcattcgtta
     2101 aaaaactgct gatagaccat ctcttcatca atcataggaa aaagccattc ccttttatgt
     2161 tcttttattt ggcaaagcca tgagttgaaa tcaggaactt tctggttttc caaggcttct
     2221 tcgtacaaca ttcgataaag aaaaacctgt tcttgtaaat aaaagaaaaa ccgacttttt
     2281 tgatagatcc acgatgatag atgcaaaaga tgtttatgac gcaagtagca ttgttcttgt
     2341 atggatactg tattcttttg cttgtgaata agttggcgtg tcagccattt cttcccatct
     2401 tcactcactt tttctatttt tttcatttgg ttcattttaa tttcgttact agtgaatatt
     2461 tctttaaggt ccctactaga aaaagtccag cagctactgc aaaaggaaat atgccctgat
     2521 acagtctctg taatatgatg atacaaataa agcttttgtt tcttgagatc agctttccag
     2581 caatgcactc ctctttttct attatagtag caacaacttt tttctatcaa tgagaattgc
     2641 gattgtccaa gaaaagaatt accaagtatc caccatactt ggtaactgtt attcaaataa
     2701 ttttgggttc tttcaataaa tctctggtga gacagtctag aacattggat ttctattgct
     2761 agattcgcca acaaaatatc cggcctttgc cgcaacctcg gcaaataggc ttccaaaaat
     2821 actggttcta ctgactgtcc cagccaatcc atgaagcatt cctttaactg taagtgctct
     2881 tttgattctc tttcactaaa gaccgaacag ttatctgatt tttgatgggc aaaatgagca
     2941 cattttttct ttcccttttt caaaatcact ctttttcgac agccacgaca ataatatttc
     3001 tttccttttt ctgcatgttt agcaaaacag cacttattat attcattcat tgcaagcagc
     3061 atttttctcc ctctgaactt atttacgtct aagaatttat ttacacgaaa aaagagggcg
     3121 tgaaaaagct attctgcatc aagtaataag aacagctaaa caaaaatagt tcccaatatt
     3181 tttcgtttgg ttgggcttgt taccgcagat gcaagctttt gaacacattt atacgaaaaa
     3241 aagactgcga cacaattttt gtcacagtct cttactataa tgctgattta tacaaaataa
     3301 aatttcgttc gctcgatagc attacgcgcc atcagacatt gtccatattc attcaatgtt
     3361 tctggtgtac gatcgctctt ttcagcaaac tccaaaattc gagcaatctg attctctaca
     3421 tccgcttggt tgagattttc catccagaag tgaacgacta ggtaatagcg ctcttcgaat
     3481 aaatacaaat cagtccaagc agactctagt tcgacatctg ttgcaagttg gatcacttgt
     3541 tcaaaatctt caaaagcaaa agttgcttgt ctttcctgtt cttctagggc gcttccagat
     3601 aattcttcct ccggatcgct gccaataatc tgctgacgaa gaaagtcact cacatcttct
     3661 gaatcaacag tagaatcttc tgattgagaa atttcttcat ccggaagatt tttactgata
     3721 aacagttcta atccgtctcc ttttggcaaa acttggaaag tgacagcttc gcttcctcgg
     3781 aactcctctt cgatatcaac ttcttccaaa atactataaa agaaattttc gatttctttg
     3841 tgattgccaa gtaaatccaa aaatgaaacg ccccgttcct ctaaatcttc atgaccaatt
     3901 agtacacgga tcgtattttc attaatatgt tccatttcca ttttgctaca cctcactttg
     3961 ccacaatgtt taatatagat tcattgtagc gaaatcagct taaatgtaaa gaaaaaaaat
     4021 ctcgctgtta agcgaattta ataaaaccag cggatttttc aacctttcaa gctatcttat
     4081 ttaactataa catttttggc agacgaatac tatatagccg acttttcagc taattttccc
     4141 tctctatttt tcgtgcaatc atcatcttct actacctttt tatacatcta atcaagaata
     4201 ctttttgtaa aaacaaaaaa acttggaaaa actatctttg taatagtctt ttccaagttt
     4261 cgtattatcc ttctataatc cagccatcaa ttgtgcttga cgtaattcta attgtcgtac
     4321 atcgcgcggt aggaaccgac gaatttcatc ttcattaaaa ccaacttgca gacgtttatc
     4381 atcaatcatg attggacggc gaagcaatcc aggattgttt tgcacaagtt ccaataattc
     4441 ttgtaacggc agatcatcta aatccatgtt cagtttttgg aatactttgg aacgtgtcga
     4501 gatgatttct tctgttccgt cttctgtcat ttgtaaaatc gcttttaatt cagaactgtt
     4561 caatggttct gaaaaaatat tacgttcaac aaatggaatc tgatgttctt gcaaccacgc
     4621 acgagccttt ctgcaggaag tacaacttgg ggaagtatat aatgttaaca acgtgcacca
     4681 ctccttttcg tgataagaat cacttttttg taacagaaga tcataata
//
LOCUS       DASHWW010000120         4679 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.124, whole genome shotgun sequence.
ACCESSION   DASHWW010000120 DASHWW010000000
VERSION     DASHWW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.124"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(91..954)
                     /locus_tag="U2R64_002784"
     CDS             complement(91..954)
                     /locus_tag="U2R64_002784"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEM8919530.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(1096..3669)
                     /gene="mprF"
                     /locus_tag="U2R64_002785"
     CDS             complement(1096..3669)
                     /gene="mprF"
                     /locus_tag="U2R64_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEM8919531.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            3810..4616
                     /gene="proC"
                     /locus_tag="U2R64_002786"
     CDS             3810..4616
                     /gene="proC"
                     /locus_tag="U2R64_002786"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEM8919532.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT         1462 a         1025 c          809 g         1383 t
ORIGIN      
        1 tcatatctag ccatttcact acaataaaaa actgaagaat accattttag gattcctcag
       61 tttttcatca cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc
      121 ctcacaaaaa ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa
      181 ggcaaaaacg gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat
      241 acgctctttg atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt
      301 tcccattttt ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg
      361 gatgtcttga tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac
      421 actcattctt ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat
      481 ttcttcccct ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt
      541 accgacttcc aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg
      601 gttgatccct cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac
      661 tggaatattc ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag
      721 caataaagca gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt
      781 ttctacaatg attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac
      841 gctcgacatc accatttcca actcatgata cccatcttgc cgtctatata atacatccag
      901 tcctaaattt atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa
      961 agtctaagtc gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta
     1021 gtggttgatt ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac
     1081 aagttctagt gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc
     1141 tttttctttt cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt
     1201 cctataagca aaataacgtc cttcccaatg atcgacatat tttaatttct tttcataagc
     1261 agactggaag gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg
     1321 aaagaaagaa aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc
     1381 cgagtagccc attttctcgt atacaataaa cagattggct aacagatagt cagctaattc
     1441 ctcagattct ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg
     1501 ctgagcggtg atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga
     1561 taatacatat gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag
     1621 ccatttttgt gaaacttcat ttacagcttg atgtaattct tccggcagtt gatcgtacca
     1681 agtaaaatgg tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga
     1741 caagtcttct gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc
     1801 caattcatga agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc
     1861 taaacaatct gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggattgcc
     1921 aactggatct cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg
     1981 atcttggtcg tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct
     2041 tgtagctgtg cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact
     2101 gccaagcttc gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga
     2161 gatgcccaaa ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg
     2221 atttcctgtt attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac
     2281 gataaacaaa aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa
     2341 ttttgttcga taaaattctt ttctggataa ccacacagct aacagaatca agacatatac
     2401 caatatcaac tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa
     2461 agcaatcgta ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag
     2521 taataaaaag ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa
     2581 taatacttga aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat
     2641 catgatcccc gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa
     2701 cagtcgcgga atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa
     2761 tagaagtccc gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac
     2821 tactgctaca tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa
     2881 agtccccatt ccacctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat
     2941 aggatagatc gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac
     3001 cgcaagggct cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg
     3061 ataaaactcg aagaacaatg tctttctctt tagataagca aaaaagaaaa tgactggtgc
     3121 taaaaaacta ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat
     3181 aaaaaagaca tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag
     3241 tgcgactttt gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact
     3301 agcccgcaga cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt
     3361 tacccacgca gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa
     3421 gactctgatc gtcacccaat catacaacaa catcggagtg acacccagca gtccagccag
     3481 aatcatgagc aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca
     3541 actcatgcca ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa
     3601 aaaaatcagt tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt
     3661 atttttcaca ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttatct
     3721 tatttatttt aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa
     3781 gatatcctaa tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata
     3841 tggcacaagc tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt
     3901 tcgtttccag tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg
     3961 catgcaaaag taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac
     4021 caaaaatcat tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca
     4081 tttctattgc ttcaggaaaa tcattaacag atttagaaac agcgcttgaa gatcctcagg
     4141 cctccatcgt acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga
     4201 tttgcaaaaa tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag
     4261 caatcggcag cgtctatcct ttagcagaat cagatttcag tacattcatt ggccttgctg
     4321 gcagctcacc cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga
     4381 atggtttgtc caaacagaca gccactgaga ttgctgcaaa agcaattatg ggttcttgtc
     4441 aaaaattcct ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg
     4501 gcggtacaac tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagcaatca
     4561 tcaaaggaat caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat
     4621 agcaatgttt tttcgtacct tacaaaaaaa gaagagctgt ggcttttgcc gcggctctt
//
LOCUS       DASHWW010000121         4661 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.125, whole genome shotgun sequence.
ACCESSION   DASHWW010000121 DASHWW010000000
VERSION     DASHWW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.125"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(172..474)
                     /locus_tag="U2R64_002787"
     CDS             complement(172..474)
                     /locus_tag="U2R64_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919533.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="U2R64_002788"
     tmRNA           complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="U2R64_002788"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1231..2004)
                     /locus_tag="U2R64_002789"
     CDS             complement(1231..2004)
                     /locus_tag="U2R64_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8919534.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2148..2498
                     /locus_tag="U2R64_002790"
     CDS             2148..2498
                     /locus_tag="U2R64_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEM8919535.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2479..3195
                     /locus_tag="U2R64_002791"
     CDS             2479..3195
                     /locus_tag="U2R64_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8919536.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3195..4643
                     /locus_tag="U2R64_002792"
     CDS             3195..4643
                     /locus_tag="U2R64_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8919537.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
BASE COUNT         1550 a          822 c          899 g         1390 t
ORIGIN      
        1 ttataattgg agtggtagtt aattagtgac ttatttttga ttttatagca ctgatactat
       61 aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat atccctttta
      121 taagtatggt gataaaatcc gttccgggct acctttttta ggtagcctac tttaatcttt
      181 atacctttct ggatcaacga aagtatactt caaatagtca taacgccgat gatcgctccg
      241 tgcgtctggc acatcagtca cgatatcaaa caaaaaatac acatctttct tcattctggt
      301 ttttgttgcc ggaattttaa agtagttctt attagagtaa tagagattga ttaataagct
      361 atcttcgatt gctaaaaaga aaacttctga atcccacacc ttataaaaat ctttgacaaa
      421 tctattcgaa ggatcaaatt taaaccataa ttgtgttttt ccttccatca acataatgtt
      481 cacctcaaaa agagtatacg aactaatgtt ctttttgtaa agtaggaata tcattgataa
      541 tatggatgga acatatatat taaaaagtgt tctttttgaa tgctattttg aatgccattt
      601 tcattcattt aacgaaaatc tgcgaaaata aaaaatgctc aaacccttat aaaataagga
      661 tttaagcatc tagcgaaatc tgctgaaatc tcacaatgga gacggcggga gtcgaacccg
      721 cgtccaaaca catcgccact taaaaatcta cgttcatagt caactcattt aaggattcac
      781 tttacagctt gccgagtgac aggcattctg tatcgctagt ctgatgttct ctttttcaac
      841 ttacagacgg aaagttgaaa cgtatcccac taaagttagg acccttactc gagcacatgg
      901 gcgatgccga gaggatctac gctaactgtt tttaggcagc taaagcgtaa gagttgtttt
      961 cgtttttagc agttatattt aactgtaacg tttttacgta gacgtaacct acgaaacgca
     1021 attcaagctc gactgtgcct gtcgaatccg taacgtcccc gttagctaac aagggttacg
     1081 tgtatttttc atacaaaatt agtatagcat atattgggat aaattcaata aaaaagcgaa
     1141 tcatatccca ttatttatat aataactgcc cctttcttaa gaaaaaataa gcgattttct
     1201 taagaaaaga ggtagcttca aaaaaagatc ttaaatcaga tcaaaatact tcaatgcgtg
     1261 gacaattccg ccttctgtat ttttctttgt gataaaggta gaaagttctt ttaatccgtc
     1321 ataggcgttg cccatagcga ttttgttgtc gcaagcttcc aacaaggcaa aatcattcgg
     1381 accatcgcca aatccaaaag taggaacttt ttccagctga agttcttttt gcagacgttt
     1441 gacacctgcc ccttttgaga ttcctttctt cactgtatcg atcgagtaag gaccattccg
     1501 ataaaaagtt agctcaggaa aatgttcgtg atagtattcg tcacctgatt gagataagat
     1561 cagcaacata tttactgtgt tttctttaaa gcctaaagga tcaatttccg gaacatctga
     1621 atgaatgaag tcgtaagcat tgatcattgt ttggctatga ccggtacacc agattttctg
     1681 atcgttatag taagaaagtt catgaccgtt caactgtaca tgatcataca ttttttgaca
     1741 ttcttctgaa gaaaatgttt gagaatagat ttcttcgccg tctactcgaa tgaaagaacc
     1801 attcatggtg accgcagaag taatgcccgc atcttccatg atagagtgga tttctgcttc
     1861 tgtacgtcct gtagcgatga cggggagaac attgttttct tttaatgcgt tcatagcttt
     1921 tgccacttcg ggtgtgattt ttgatttcgc atctagtaat gttccatcaa gatcaaagaa
     1981 agtgattgca cgataatttg acacaaataa aactcctttt ttattggaat aagtttatct
     2041 taacaaagaa tgaacaaaag acaaaccttt cgtgaagaat tcctgaacat attggttcag
     2101 tcaacaattt agagtatact ataagaagag aatttaggag ggaaagaatg atttttttca
     2161 gtattggtat cttattctta ataattggca gtctttttcg gattctgccc tcaaaaggaa
     2221 atctgccttt ttatgggtat cattcgcctc ttgccgcaaa aacagacgct cattggcggc
     2281 tggctcaaaa gacaagcgga aactggtttt ttcttatggg cttactgatg gcattgatcg
     2341 gctattattt aaagacatct gggcatacga attattttct gattgaaatg cttctgctag
     2401 tatttccaat tatgcctatt tttattatga cagaaaagaa attacagaaa tatgacctgg
     2461 aaactggagg gaacgataat gaatatttta atgattgaag ataatcaatc tgtttctgaa
     2521 atgatgcaga tgtttttctt aaatgaaggt tgggaagcaa ctttcaagta tgatggaaaa
     2581 gaagggctcg atgccttttt agaaaaccca caacattggg atatgattac actagacctg
     2641 aatttgccca cactggacgg tatgctagta ggaagagaga tccgcaaagt ttcaagtact
     2701 gtgccgatta tcatgctgac agctagagat tctgaaagcg atcaggtgat cggcttagag
     2761 atgggggcag atgattatgt cacaaaacct ttcagtcctc tgacgcttat tgctcgaatg
     2821 aaagctttgc atcgccgtag tgagttggca gaagcaagag aagaagcagt agtttcagat
     2881 gatcattttg atatcgagac tagtcatttc aagatgaata cgaaaacacg agaagcgtat
     2941 ctggacaacc ggccaattga aggactgacg cctaaagagt tcgatctatt gtttacttta
     3001 gcaaaaaaac cacgtcaagt attctctcgg gagcagttgc ttgaattagt ctgggattat
     3061 cagtactttg gtgatgaacg gacagtggac gcccatatca agaaattacg acaaaaaatc
     3121 gaaaaggtcg gaccacaagt catccaaact gtttggggag tcggctacaa attcgatgat
     3181 tctggtgttg cctaatgcgt tatttgtatc agcaactctt agctttctgc ggaatggtcg
     3241 cgttgatctt attgatcgtt ggagtttctt ttacacaact gacaaaacaa acgattgaag
     3301 aaaacaatta ccagcaactg tttggatatg ctgaatcagt tgaaaagaca acgcaaacct
     3361 atgccgatac gctcccgcag tttagtcaag atcaggcgtt tcaaaatgca ttgctgctga
     3421 cagagcaagt actgacagaa caaaatgtga actttatatt tatcgataaa aacgaacgtg
     3481 tcatttatcc gactaataca gctttactga attttacctt aacagctgat caatggaaaa
     3541 atctgaggaa tggacgtcaa gaaaaattca catcgaataa aaatatttta ggacaagcac
     3601 aggcgacctc ttacgcactt gtgccattta atttgaatca tgaattctat ggagcacttg
     3661 tagttagtca acctgcgcga aatatcgata acagcgttcg tccaattaca ctgaacctgt
     3721 tcaaaggatt tattttttcc agtatcgttg cagttattgc cagctatgct tttgcagcat
     3781 tccaagttaa gcgtatcaat cggttaagga atgcgacgaa agaagtgacg aatggtaatt
     3841 ttgatgtaca gctccccgta catgacaaag atgaatttga tgagttagca gatgatttca
     3901 ataaaatgac gaattcattg aaagaatctc aagcagaaat tgaagaacaa gaaaatcgtc
     3961 gaagacaatt tatggcagat gcttctcacg agatgagaac acctcttacg acaatcaacg
     4021 gacttctgga agggttagaa tacaatgcaa tccctgaaaa tcagcgagaa aacgcgatta
     4081 aattgatgaa aaatgaaaca gagcgtctga tccgtttggt gaatgaaaac ttggattatg
     4141 aaaaaatccg tacgaatcaa atcagtatgg tcattaaaaa attcaatgga acagaaacat
     4201 tgaaaaatat tgttgcacag ttagaagcta aagcagaagc agcaggagat acattgacat
     4261 tgaaagccgt tgatgatatt gatgtttacg ctgattatga ccgatttgtc caaatcatgg
     4321 tcaatattat tcaaaacgcg atacagttta ctgaaaacgg ccaaatcacg attactttag
     4381 aaaaaggcta tcttgaaacg atcatcacga ttgaagatac gggaattgga atgtctgaac
     4441 aacaaatgaa aagtatctgg gatcgttatt ataaagtaga tccttcaaga aaaaatacaa
     4501 aatatggtga atcaggatta ggtttaccaa tcgtgcagca acttgtacgc ttgcataaag
     4561 gaaaattaga agtagaaagc gaactaggaa aaggaacaaa attcgctgtt cgtttgcctg
     4621 acgtagaaat caaaaaagag taaaaaacaa gcggtataaa a
//
LOCUS       DASHWW010000122         4620 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.126, whole genome shotgun sequence.
ACCESSION   DASHWW010000122 DASHWW010000000
VERSION     DASHWW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.126"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(17..964)
                     /locus_tag="U2R64_002793"
     CDS             complement(17..964)
                     /locus_tag="U2R64_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HEM8919538.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1142..1945)
                     /locus_tag="U2R64_002794"
     CDS             complement(1142..1945)
                     /locus_tag="U2R64_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEM8919539.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2091..3005
                     /locus_tag="U2R64_002795"
     CDS             2091..3005
                     /locus_tag="U2R64_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEM8919540.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3053..3523
                     /locus_tag="U2R64_002796"
     CDS             3053..3523
                     /locus_tag="U2R64_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEM8919541.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3608..4216
                     /locus_tag="U2R64_002797"
     CDS             3608..4216
                     /locus_tag="U2R64_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEM8919542.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4350..4550
                     /locus_tag="U2R64_002798"
     CDS             4350..4550
                     /locus_tag="U2R64_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8919543.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1513 a          716 c          912 g         1479 t
ORIGIN      
        1 atattgtttt cagctattaa tatcctgcag acaattttac ttgattggtt tgaagctcat
       61 gggtggcaaa gtagcttttc agattggtta aaaaaatagc cattaatttc ttttgaaaat
      121 caggtgtcaa acctgcaatg tgggaagtaa tcagtacatt gtccattttc caaagaggat
      181 gatcttgtgg aagaggctct tcctcaaaaa cgtctaatgc tgcaaaggaa agttgctggt
      241 tatttaaagc ctgcaccaga tcttgtgtct taacagaagc accacggcca acattgatga
      301 atacagattt tggatcaaag tgttcaaaca tatgctgatc aaagagccca gttgtttcct
      361 ccgttagagg taagatattg actacgaaat ctacttcagg aagaacttcc tttagttgat
      421 ttaaagaaaa agtcttttcc attccttctg ctggatgacc ggatgtattg attccatagc
      481 agttcatgtc taatgctttg catttttttg caatcatttt tccaatatgg ccagttccaa
      541 tgattagtat ttttttccct tggatagatt ggtaatggac cgatgaacct aaccatttca
      601 tgtcactctg tgccttttgt gcttgaaaaa gaccacgaga atacccaagg atgattccta
      661 agacatgctc cgtaatcgat tcactgtgga tgccactacc atttgaaagt aaaatatgtt
      721 tctttgaaaa agtctcaagg ggtagctgat caacaccagc tgagatagat tggacccatt
      781 tcaaggtaga agaggctaat agtttttctt ggtagtctga gttccagccc aaactgatct
      841 ctacattttg tagatcctct ggttgtaatt ctgttttaaa gatataacca ggcgctatag
      901 tatggatttc ttcgataaat tcatcacgaa atggacgatc tgcataaatg attctttctg
      961 acatagttaa tttcccgcct ttctttactc taagtgtagc gcatacaaga agaactttga
     1021 agcgccttgc ttgttttttg agaaagaaat atttttcaaa taaaaaaggg gctgtgacaa
     1081 aaaaatgtca caacctctaa aagggtctat tgaagtagaa ataacgagtt gtctttattt
     1141 cttaattgat cgatattttt gcccatcctt tgacagcttg agcaaaaata aagattcctg
     1201 caaaagcaat gaaggcgcta gtgtcaaaag aaggaagaaa gaccatcaag attgttgcaa
     1261 ttatagtagg caatgaaatt gaatagatca atgtttttaa acaatcaaga aaagtagctt
     1321 ttgttagtcg aaagcgtgca tagagaaaag cagcaatgtt ggtaaatagc aaagtgatca
     1381 gcagattcag aaaactagga taaatagaaa atataaatgt caggactttt atccaaagtg
     1441 gtatagatgc ttcacttaaa aaagaacgga gctgcttacc tgttaagttt tttaaagatt
     1501 cattggtgta gggaagttct aattggttat tgttcaacaa agcagaagtc gtgcctgtat
     1561 taggaagagc tatgataagt ttgtttttta acatcccgac actaacaaaa ttccccatca
     1621 aatcagtaga gatgtcctgt tctgttcgtt ttccctctgg atcaaatgtg aagataatgg
     1681 agtttgtttg gtaaatgaat ccttcttttt cttcggtttg aagctgcccg ttttggattg
     1741 taaaatcagg aatgcgagta gcaatctttt gcccatccaa ttgaatgttg tttaagactt
     1801 gaaaaacttg aaaagagatt ggcaaagcca taattatact caaaactaaa agatagacaa
     1861 tggctttcca aaatgggaca tttctcgcct cctttaggtc tttgaatcgt ataaaggaac
     1921 tgataattaa ttgttttgtt gtcataagta ctcctcatct agtagtgtca tcacttgcaa
     1981 ttctagcgaa gtatcaagtg aaatacaagt gctttaagga aacagctgaa tgattggtga
     2041 aatatcaaaa aaatgttatt cttgtctaaa gactatccaa tataaataaa atggaggaag
     2101 gaatagtgcc tacacagcca cagagatcat caaaaaaact atttggagta gtggttttga
     2161 atgcggtgat cactttatca gaatttattg gagggattat gtcagggagt ttgtctcttg
     2221 tttcagatgc tttccataac cttagtgata cattggcaat tattttttct tacggggcac
     2281 aaaaaatggc ccgaaaagaa gcaaataaaa aacgtacgta tggctaccag cgtttagaaa
     2341 tattgagtgc tttcatcaac tcattcatat tgatcatatt atccttgttt ttaaccgttg
     2401 aagcattcaa gcggttcact tcaccagaaa agataaatag tcatttgatg ctaacagtag
     2461 cagttattgg attgctcgcg aatttgttct cagtattatt attacgacaa gaagcagatg
     2521 aaagtttgaa tataaaatct agttatttgc atttgttaag tgatacactg tcttcggtaa
     2581 gtgtgattat cggagcaatt ttgatccgtt ttttcgatat ctactggatc gatccagtta
     2641 ttacactgat catttcgata tatatattga tagaagcgat aatggtgatc aaaaaagctg
     2701 ccgctatttt gatacaaagt gcacctgcta tcgactatga aaaaatggaa caagaaattg
     2761 aagcaatcga tggggtaaag gatgttcatc atgtccatat ttggcagtat agcgaaaaga
     2821 taattatttt cgacggacat attgattttg aagatcagct actaagcgag attgaaaaga
     2881 tatatcctcg tataatttct ttattaaaat taaaatatgg tattacacat gtgacgatcc
     2941 aagcagagac aaaggcaaag gatcaaaaaa aattaatttt tttaaataaa gatgaaagtt
     3001 attgaaatat agagtatgat aaataagaat ttttaataag gtaggttggc tcatgaagca
     3061 gtatcgacag ttaaaaggat atttagaagc aaaaggatat tgggagatac tagtctatct
     3121 cttttttggt ggtttggcta cgattgtaaa ttttgttagt tttgctctcg cacgccaata
     3181 ttttgattta agtatggcct tatccaattc tatttcgtgg ttttgttctg tattgtttgc
     3241 ttttgtaacg aacaaacttt gggtattcca ttcaaaatca ccgaatttta cacatgcact
     3301 tattgaatgc ggtaagttct tcttctaccg tatcctttct tacggattgg acatgggggc
     3361 aatggtattg ttgatcaatg ttatgaacag caatgagtat gtggcgaaaa tcatcactca
     3421 aattattgtt atccttgcga actatatttt cagcaagttg tttattttta aagaaactga
     3481 ggtttttgaa gaagaagtag gtcaaagtga aaaagacgac taggcataac aattgaagaa
     3541 tttccttctc tttgttactc tttgtaatgt agacattatt aagaaaacat tgaggaggaa
     3601 tttttttatg acttacacat taccagatct accttatgca tatgacgcat tggaacctta
     3661 tattgacgaa gaaacgatgc atctgcatca tgataagcat cacaatactt atgtgacgaa
     3721 tttaaattca gcaattgaga aatacccaga attaggcgaa aaaacaatag aagaattatt
     3781 atctgatatg gacgctattc caacagatat caagacagct gtacgtaaca atggtggcgg
     3841 acatgctaac cattcatttt tctgggaaat catggcacca aatgctggtg gcgaacctac
     3901 aggagaaata aaagaagcga ttaatgaagc ttttggtgat ttttcttctt ttaaagaaga
     3961 attcaaaaaa gcagccgctg gacgatttgg ttctggatgg gcttggcttg taatggaaaa
     4021 tggaaaatta gctattacct ctactgcaaa tcaagattct ccattgatgg aaggaaagac
     4081 accaattcta ggtttggacg tttgggaaca tgcttattat ttgaaatata aaaatgtccg
     4141 accagattat attgcagcat tctggaatgt tattaattgg gatgaagtaa acaaacgttt
     4201 cgaagcagca aaataaccat ttcctccgtc atatcagtct taaaaataat ttggaaaata
     4261 aaagagcgaa agcttgctag cgttttctaa attgggtata atgttcttgc aaggttactt
     4321 gcaagaactt ttttggagga tatacattta tggaacacgg aacggttaaa tggttcaaca
     4381 atgaaaaagg atttgggttt attacagtag acggcggaga tgacgtattt gttcatttct
     4441 cagcaattca aggagacggc ttcaagagcc tagaagaagg tcaagaagta gaattcacga
     4501 ttgttgaagg tgcacgcgga cctcaagctg ctgaagtgac taaattataa taatttgttg
     4561 aataaagaca cgacttctta gagagtcgtg tctttttgtc tatttatgaa gtttttagat
//
LOCUS       DASHWW010000123         4486 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.127, whole genome shotgun sequence.
ACCESSION   DASHWW010000123 DASHWW010000000
VERSION     DASHWW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.127"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(333..863)
                     /locus_tag="U2R64_002799"
     CDS             complement(333..863)
                     /locus_tag="U2R64_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8919544.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1045..1701)
                     /locus_tag="U2R64_002800"
     CDS             complement(1045..1701)
                     /locus_tag="U2R64_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEM8919545.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1828..2301)
                     /gene="dfrF"
                     /locus_tag="U2R64_002801"
     CDS             complement(1828..2301)
                     /gene="dfrF"
                     /locus_tag="U2R64_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HEM8919546.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2720..2938)
                     /locus_tag="U2R64_002802"
                     /pseudo
     CDS             complement(2720..2938)
                     /locus_tag="U2R64_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2969..4183)
                     /locus_tag="U2R64_002803"
     CDS             complement(2969..4183)
                     /locus_tag="U2R64_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEM8919547.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1383 a          948 c          658 g         1497 t
ORIGIN      
        1 aaaacgacaa tcaatttctt attttttgaa atcaactgtc tttctcatat ttactattca
       61 attttcatag tgatataggt acaatttata tcactactgt aaaaatgggg ttttgcctta
      121 taaatacagc gttttccgct tgttagtgta tagtgtttct tgttttttgt gccccccttg
      181 ttagataacg ggggctttga acggctcgca agctcgccga accgccgaag cgaaccgccc
      241 ccttgcaagc atggcggaaa aatcttaagg attttcccgc caacgtggtc ggatcgctcc
      301 gtcggtttaa cagcttttct gtttctctct agttatctac gcatataaat caaatcggtt
      361 attccgttat aagtctgtgt tttacaaagc cttaacttta tttccctgtc tatgttgccc
      421 aaaagacgaa ccccatttcc taacagagta ggaataacag aaatgtaata tttatcaatc
      481 atatttttgc ttaccaactg ctgaacaaga tttgctccgc cacaaatcca aatatccttt
      541 cctgcttctt gttttagccg ttccaataat aaaacaggat tttcacttgt aaaatgaatt
      601 tgttgggaag aattgcactc tttatgtgtt aatacataag ttgtaaattt attatatacc
      661 cattcttgcg gagaaagttc agtaacaacc tgatgagaag tattccaccc cattaagaca
      721 gtatctatat ctttggtaaa ttctgtataa gtgtcgatgt tttcattgtc atttccatga
      781 ccatttagcc aagctactcc accattaccg tccgcaatat atccgtcaag gctcatggca
      841 ataaataaaa ctacttttct cattttttct cttttataaa tacaaacagg aatttatttc
      901 tcttttttac tcataaggga acaactgatt gctacaaata aacccattaa aatccatgga
      961 aatgctgctc ttataaaatc actaaccata ctttattcct ccttaaattc caatttcctt
     1021 agttctacaa actgaaattt ttgcctatga atgtatcttg ttctttatac gcaaacaggc
     1081 ttctgtgtgc ataatccaat gtcttgaaaa cggcatttga attagtccac aaatatcttt
     1141 attacaccaa taatcaatca gccaaattgc tttttcattg tcgtttacta cattcaacga
     1201 ttctaagtat ccttttcttt ctttcggtat ttttcttttc aattcatcat aagataaccg
     1261 ttcaagcatt ttctcagtgc tttcccatac ttcgaaaata tataaatata attcttccag
     1321 attaagctgt tttgaaaagt ctgcaatctg ctgtttcatg agttcatttc ctgttgtaat
     1381 gataggtgaa ttgatacgct cttgataatt gcctgcaaaa aatacttgtt catcttcatt
     1441 tatcactgta tgcacaacta tatcttcaat gcggaaaata tgccaaatag aataagcaat
     1501 cgtcttacta tgataaccat cagcgtttat gaaggggatt gagttaaaat cttctctgca
     1561 taattcttct ttgaaagata ctaaggtttg tattaactga cttcgtaaag taagtaaagt
     1621 atcaataccc ctcttataag tatctttctt ttttatttgt gcctgcattg ttttattaag
     1681 ttcagaccat tccttattca tattcaatcc tctctcaaat tctgatttta tcgccccata
     1741 caaactggaa tttgtcttac aacaatttat atatgcataa aaagcaatat atttatgaaa
     1801 acaccctaaa tccaaaattt actcaattca ttttttcctt acataaaatg ttctcgtata
     1861 tttcacttcc tcaccaagtg tttcccctat caaaacttca aaatcattga tatcaaattc
     1921 tggaaagaat gtatctccat cttcaatatt taaatctact tctgtgatat acattttatc
     1981 tactatttgc aaagcttcct taaatagtcc atatccacca gatatgtata catctcgtcc
     2041 tttagccaat aataatgcat cttctaatga tttaactgaa actaaattat ctccttgata
     2101 ctctgttgtg gtggaaacaa caatattcat tctattaggc aacggatgac cgatttcttc
     2161 ataagacttt cgccccataa taaccacatt acccgttgtt aactctctaa attgcttttg
     2221 ttctcccttt attttccatg gtatattacc attcttgcct ataacattat tctttgacct
     2281 cgcaacaatc aaacctatca tctatttcat cctccataat atgatgtcgt acctgtgatt
     2341 ccatcaagtg caccacatct taacaaactc aaaattatct cgaactaacc agctcgacaa
     2401 attccttttt tgtcttcatc tgcattatat catattgtta taagcattgc catttctttt
     2461 ctgcttttga aaagttactt atcagcctat gttttgtaaa gggtgatatt cagcatttct
     2521 cacgcaacaa gcccttgaca aaccatagac taataagttt taaggtaatc aagcagaaat
     2581 gaaatagtct gctgtttcac ggcaacaaaa aagagatacc aacacactta tgtagtatct
     2641 cttagtctag tagcaatatt cttttgtttg caagcaggta aacatgggct gtttcttaat
     2701 atctttttgt ttgggaaaca cctttttccc atcctttcac cgttgccatc tctgctgcgc
     2761 acaatgccac agggataaac catagcaaac cgcctaataa caagaaaaat actaagctga
     2821 agcctgaggt cgcgaatgtg ggatattcat ataatgaaac gaccattgag atggtcatag
     2881 ccaaaaagcc aaagaacgtt aatttttttg caggaatttt cgttttgctt tgttgcatga
     2941 atcttcctct tttctatttg aatttgtttc aattgagttt gttgccaaag aagaaaaagt
     3001 ccaatccttc ttcttgttct tcttttgtag tagtgatcgt tgtaaagtgc atcgccgatt
     3061 ttaaaatcac tgttgtcagc acataggcat acacggcagt aatgatgaca ccaatcactt
     3121 gaatccctaa gaagtaccag ctgcttggat tcgttagtaa atggctgtta gatgcaaaga
     3181 tccctatcag aatcgtacct gtgaatccgc ccatgccatg aacaccccac acatcaagtg
     3241 catcatccca ttgtttcttt ttacgaaaat caacagcagc atgacagacg atacccgcaa
     3301 tgatcccaat cagcatggca ctttttgctt ctacataacc ggcacaaggc gtaatggctg
     3361 ccaatccagc aacggatcct gttagtacgt cgacaaaatc aaagccattt ccttttactt
     3421 ttgcaatgat cagccaagta atcatcgcaa atgcaagagc gatgaatgtt gaaccaaatg
     3481 cattgactgc ttgttcatct gctcgaagtg caccaccgga attaaaaccg aaccagccaa
     3541 accaaagcag tcctgtaccg atagcagctg ccataagact gctatgctga cttctttctc
     3601 ctaaaggaat ctttctttga ccaagtgtga ggatacatgc taaagagccg aatccagctg
     3661 tcgtgtggat gactgctcca ccagcgaaat ctctaaatcc catctgatcc aaaaatccgc
     3721 caccccatat ccagtggcaa acagggaaat aaatcagcag attccaaaaa ataacaagta
     3781 taatatagcc ttttaaattc aatctccctg caaaagctcc tgtcatcaaa ggaacggtaa
     3841 tcacgataaa catcagttgg taaagaaaga acattaaaaa tggaatcgtt gcaccatgaa
     3901 acatgttggg gaagcttgta acatgtctca tcaaaaagaa atctgccggg tttccaataa
     3961 caccgccgat atcccgtcca aaggccaatc cgaatccacc aaatacccac ataatcgttg
     4021 ttatcccaac ggagagaaaa gattgagaca tgatcgttag tatattattc ttccgtgcta
     4081 atccgccgta aaaaaaagct agaccaggag tcatcaggca aaccattgct gtacataaaa
     4141 tcatgaatgc tgtatctcct gtattgatag gtaatgtatt catttttttc gcctcctttc
     4201 tacgattacg agtataaaag aaggtgtagt tgtttttttc ttctgttttt ttgaattaat
     4261 acttgcattt ataaaagaca gacaattaat aaaagcttga tgtgttgtgc tctttttcgt
     4321 ttttcacaca aataaagaca aaaaataaac ggtcttcttt ttatagaaaa ccgtttattt
     4381 tcgtcttttt ttatttttaa agatattttt tcataaggaa taaagaatac ttcatataaa
     4441 atatataaaa aagaaccgca gcgagtgtcg ctacggttct caaatt
//
LOCUS       DASHWW010000124         4433 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.128, whole genome shotgun sequence.
ACCESSION   DASHWW010000124 DASHWW010000000
VERSION     DASHWW010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.128"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(543..2048)
                     /locus_tag="U2R64_002804"
     CDS             complement(543..2048)
                     /locus_tag="U2R64_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8919548.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="U2R64_002805"
     CDS             complement(2045..2731)
                     /locus_tag="U2R64_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8919549.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="U2R64_002806"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="U2R64_002806"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEM8919550.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DASHWW010000125         4307 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.129, whole genome shotgun sequence.
ACCESSION   DASHWW010000125 DASHWW010000000
VERSION     DASHWW010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.129"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            149..1138
                     /locus_tag="U2R64_002807"
     CDS             149..1138
                     /locus_tag="U2R64_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEM8919551.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPRMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAERLNDEIDLFNHALSKMFRRKKVQIAIKGYVRKLEITYNKEREDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGVNPDGTDEITQLDVRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1135..1554
                     /locus_tag="U2R64_002808"
     CDS             1135..1554
                     /locus_tag="U2R64_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919552.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1533..1871
                     /locus_tag="U2R64_002809"
     CDS             1533..1871
                     /locus_tag="U2R64_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919553.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1875..2237
                     /locus_tag="U2R64_002810"
     CDS             1875..2237
                     /locus_tag="U2R64_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919554.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2460..3866
                     /locus_tag="U2R64_002811"
     CDS             2460..3866
                     /locus_tag="U2R64_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEM8919555.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1501 a          602 c          996 g         1208 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt gatttatagt tttaattgtc taagtcaaaa
       61 ctaaactaga aaggagagca atcttaattt ttgttatcgg cttttcagcc ttttttgtat
      121 acaaaatttg tagattcagt atagcaagat gaaaaagaaa aagcaagatt tgattaacgg
      181 aacatttcga gaaaaaaaga aaaatttgaa aaaagtggtg gcatttagtg ataatcgaat
      241 ttctcccaga atgcgtgaat tgatgacagg ctgtggttca tatttagaat ttattgcaac
      301 gattgataag gagaaaaaga aattggtcca agctcacttt tgtaaaaatc gtttctgtcc
      361 gttatgtgct tggcgtaaag ctcgtaagga ttcgatgatg ttgtcgataa tgatgcaagc
      421 cattgcggaa gaaaagcagt atcaatttat ttttatgacg ttgacgacac caaatgtgaa
      481 agcggaacgt ttgaacgatg aaattgattt atttaatcac gcattatcga aaatgtttcg
      541 tcgaaaaaaa gtgcaaatag cgattaaagg ctatgtgcga aaattggaaa tcacatataa
      601 caaagaacga gaagactata atccgcattt tcacttgatt ttggcagtaa ataaatcata
      661 tttcacggat aaggattatt atatcaagca atcggaatgg ttagatttgt ggcgggaagt
      721 gactgggaaa acaggggtca atcctgatgg tacagacgaa attacgcagt tagatgtccg
      781 taaggtcaaa ggattccaac aagaaaaagc agtacaggaa gttgcgaaat attcggcaaa
      841 agattttgaa ctgaccgaaa gtcaagaagt gtttgacaca ttctatcatg caatgaaagg
      901 tcgtcagttg attacgttta acggtgtatt caaagaatac aagaaaaaat atgagtcggg
      961 tgaccttgat cgttataaga aaaaagatga gaatgaatat ttttggtttt tgactgcttc
     1021 gtggatgagg aaagaatcga aatatgcggt tgattatcgt gagatgagtg ctgatgaaag
     1081 aaattatttt tcaggaatgt atgtcgatga aaaatctgtt gagggggaaa atgaatgact
     1141 gattcaacgg ataaaatgac aattaaggcg cttgctgatg aactaggaat aaccaaaaat
     1201 acagtgagaa attatctagt caaagccgga tatgatcttg ctcggtacaa gaaaaatgga
     1261 attatcttgc tagacaaaga gttgattggt gttgctcggt caatttatcg gtcaaaaggt
     1321 ggtcaattga ctggtcattt accggtcaat agcacgggca gtgattttcc tttggaaaaa
     1381 gagaatgagt ttttgcgtga tcaattagct gagaaggaca aacatatttc tgaattaaca
     1441 gaaatgattc gtgatcaaca aaaattgacc ctgcttcagc aacaaaaaaa cgatcagttg
     1501 ttactagaaa atcaagaatt aaaaaatcga aaatggtggc aattctggaa gtgagatgtg
     1561 acatggataa aattgatttg agagaagaaa cagtcaatag aattgaagtg atgtatgaac
     1621 ggttagctga ttatttgaat ctttcggatg aagataatta tagtgagatg cttgaacgaa
     1681 tgatggatgt tctcaactcg gttatcaatg ctgatctagc aaaatcttca gttttgacta
     1741 atgaatttgt tcataagcat ttagcgcaaa caactgatga agctgaaaaa gaattttggt
     1801 tgaaattaat gagtcatatt atgcagttaa accaaatttc cgttattaat tccaaagaaa
     1861 aggggatgta gtttatggga atgactttag cagatattaa agtgcaagaa gaaaaattaa
     1921 aaaaagaaca ggcgaaactt cgccaacaga agaaacgatt gattgagaaa gaaaatgctg
     1981 caatgggcaa ggctcttcgc aagcgttttg ggtttgaatc ttttgctgat tttgagcggt
     2041 ggctatcgtc gatttctgac gatcagcaac acgaaaaatc agtgggtaat gagttgcgag
     2101 ctgatgaaaa atcagcacca agcgaacgga attaccctaa cgaatctgac ggaatattcg
     2161 gagggatacc gaatagaaaa agtcagatga gtgagagtgg atttgcgtca atgtttagtg
     2221 acgtaaattc acgataagcg aatattttgc atgaagcaaa ataaagcgta aaaggagttg
     2281 agagcgtgac acgctttcgg ctcctttttt cgttgtcact tgtgacggcg aaaaccctcg
     2341 gagagcgttt ggaattgtga cagtcatgtc acaattagga aaacgtttac tctttgacaa
     2401 agagtaacag aaaggtttac actcttttta ttagcgacag cgcgaaggag gggtttaact
     2461 tggggtttag tatttcgttc aaaaagggaa caaagaatac aagcatttct cataataatc
     2521 gtgagttaac tgatagccaa aaaatcaatg actggcataa gcatattgat ttcacaaaat
     2581 cggatgaaaa tatctatttg gaacaaataa atattcgtga aaaatatgaa gaattattcg
     2641 gtgaagccgt agaaaaatat aatgcaaagc agaaaagagc cgatagaaaa attgaggact
     2701 atttagcaaa ggttcgcaag gataaaaaaa tggaaccaca gcgagaattt atcgtgcaaa
     2761 ttggtactct tgatgatttt cgtactactc gtgatgatgg ttcttctact ggcatatcgg
     2821 aacaacaagc agaacaaaat cgagtgattg ccaacaaaat tttagttgag tatttcaaag
     2881 aatttaaaga acggaatcct agtttatccg tctacaatgc tgttattcat aatgacgaag
     2941 taagtccgca cctgcatttg aatattgttc ctgttgctga agggtataaa cggggtgttc
     3001 aaaagcaacc aagttttaac aaagccttgc aacagcaggg tttacgagca gataaagaga
     3061 atggtcgagt gatttggaat aattttagga atcaggaagt tgagtcaatt gaacgtttga
     3121 tggcagattt tggttgggag cgtgagttag tcggtactaa caaaatcaaa gatattcatg
     3181 aatacaaaga aatcatgagc gaaatttccg aattgcgtca aacggccgta aaagagcgtg
     3241 agagcgtttc tgatgagttg aggtatattt gtaggcaaag agaagaaaac gagcgtgaga
     3301 aggctctggt ggcttctgag agagcgaaga ttgaagaaga gaagaaaaat atgctgaatg
     3361 taaaaaaaga gatggcggtc attttccaaa aagatatggt tcctttagaa agtttcaaga
     3421 ggcttcctga tggttcgtat catttatctg ggaatgattt tgttgatttg tatcaacgag
     3481 ctacgagagc aacaaatgcc aagagaaatg ctgataacat gagtgagcaa tatttacaga
     3541 tgcttgagca aaatacagaa ttaaatgagt atgtagctgc attggaagaa gagcgtcatt
     3601 tgtctggtag aaaacaatta gcagatttac aagtggaaaa taaaaagctg aaagaagaaa
     3661 atcgctcttt acgccagcgt ttagagcgat taaaaaacgc atttcaaaaa tcgatcactc
     3721 gtttgtctat ccgttttggg cttgcagaaa aggatatggg gctttctgag gaattagaag
     3781 tattagagca ggagaaaacc ttattttatc gtcaaaacgt ctcacagcat aaattagagc
     3841 gttctgaaga tgagatcgag tggtagttac gatgtgcagt caacggtacc ggaggcggtt
     3901 tgtgccgagg ataaggagtt gacggctaaa ccactagcct attaagctga catttgctaa
     3961 aaaatggcaa gtccattttt tggccaactt agcgttagcg aagtttgggg gcgccctttt
     4021 taaagggtgc ggttttatgt ttgcatgact aagaatgagt gggaaaattt aacagcccta
     4081 tctaacaggc ggttaaatgt acaaaatatg tacaccccct taaaaatgca gtggtcgatt
     4141 gatcgaattt tatgtctttg ggttttgggg ttttaaaacg aaaaaaaggg ggcgattttc
     4201 gccctctttt ttgatgtttt ttcttatctt gatactatag gcaactattt tcggcagaaa
     4261 atcggggcta tagtatgggt ctatcccttg tggctctaag gaagaac
//
LOCUS       DASHWW010000126         4116 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.130, whole genome shotgun sequence.
ACCESSION   DASHWW010000126 DASHWW010000000
VERSION     DASHWW010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.130"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            155..316
                     /locus_tag="U2R64_002812"
     CDS             155..316
                     /locus_tag="U2R64_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HEM8919556.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="U2R64_002813"
     CDS             335..1612
                     /locus_tag="U2R64_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8919557.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="U2R64_002814"
     CDS             1622..2278
                     /locus_tag="U2R64_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8919558.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="U2R64_002815"
     CDS             2278..3654
                     /locus_tag="U2R64_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8919559.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3784..>4116
                     /locus_tag="U2R64_002816"
     CDS             3784..>4116
                     /locus_tag="U2R64_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8919560.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1628 a          453 c          727 g         1308 t
ORIGIN      
        1 ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagagag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaatta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa ataattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt taggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg tagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DASHWW010000127         4112 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.131, whole genome shotgun sequence.
ACCESSION   DASHWW010000127 DASHWW010000000
VERSION     DASHWW010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.131"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(39..281)
                     /locus_tag="U2R64_002817"
     CDS             complement(39..281)
                     /locus_tag="U2R64_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8919561.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(313..870)
                     /locus_tag="U2R64_002818"
     CDS             complement(313..870)
                     /locus_tag="U2R64_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8919562.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(883..1071)
                     /locus_tag="U2R64_002819"
     CDS             complement(883..1071)
                     /locus_tag="U2R64_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEM8919563.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="U2R64_002820"
     CDS             complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="U2R64_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEM8919564.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2067..2240
                     /locus_tag="U2R64_002821"
     CDS             2067..2240
                     /locus_tag="U2R64_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919565.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2880..3353
                     /locus_tag="U2R64_002822"
     CDS             2880..3353
                     /locus_tag="U2R64_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HEM8919566.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3362..3589
                     /locus_tag="U2R64_002823"
     CDS             3362..3589
                     /locus_tag="U2R64_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8919567.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          739 c          617 g         1522 t
ORIGIN      
        1 ttgttcttca tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat
       61 gaaacgacta atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca
      121 attgttggtc cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca
      181 atgatgtttg cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct
      241 ccaatgatac cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg
      301 acttcttact tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt
      361 gcctacagca gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc
      421 tgcttctgtt actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt
      481 gatgtctgca acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc
      541 agtactgatc aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac
      601 gatcacatct agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt
      661 tacgttatct gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt
      721 caatagacca tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc
      781 ataagtcaat tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc
      841 atttgttgta ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg
      901 atcaactatt cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat
      961 tatgatcaac aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc
     1021 aagaccccca aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc
     1081 ctcctattcc actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct
     1141 gtatgtgact gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc
     1201 gatatcttgc atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc
     1261 gttgacatgg atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat
     1321 gaactcttct tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt
     1381 tagtttgcca tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac
     1441 gactagcaag atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg
     1501 ttgcatgtag taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat
     1561 atacggcgca ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat
     1621 aacaccgatt atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc
     1681 tgtaaataac tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta
     1741 aataaagcgc taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg
     1801 aaataacaat tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat
     1861 attattcaag attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta
     1921 tttattaaat tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc
     1981 gttcttactt tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc
     2041 ttataaataa aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa
     2101 cgattggcta tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat
     2161 tcagttggac tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac
     2221 aaaattatcg aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta
     2281 tggtactttt tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac
     2341 ttttgattta taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga
     2401 tagtaccacc ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata
     2461 aaggacaaat aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa
     2521 taaacatgaa cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct
     2581 catacagttc tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta
     2641 ttgtccaata taatcccagg catctaaact agcattatag aagagacaca catagaatct
     2701 aaaataactg gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac
     2761 cttcatactc tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag
     2821 ttgttttaca ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa
     2881 tgaaatttaa aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt
     2941 tgttcggcgt acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt
     3001 ggcagaccac attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg
     3061 cttatttctt attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa
     3121 gcttaaacat actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg
     3181 gcttacttcc taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg
     3241 taggaatcgc tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa
     3301 aactgcttga acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga
     3361 catggcaatt atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga
     3421 attgagtgag aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc
     3481 aaaagccatc cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg
     3541 tgatttgttg acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga
     3601 acaaacagta aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt
     3661 acgtctatta ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat
     3721 gtactgactc atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca
     3781 actggtttcc tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca
     3841 ccagactgat agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt
     3901 tcataccttg aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat
     3961 tcttttttag taagctccca tatatactgt aaagccttct atatattatg tcatgttgct
     4021 ttttaacatt tactatgtag ttttgataaa atgatttgaa taacagtgat ggataattct
     4081 tttttatttt taacattatt ttgataataa tg
//
LOCUS       DASHWW010000128         4034 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.132, whole genome shotgun sequence.
ACCESSION   DASHWW010000128 DASHWW010000000
VERSION     DASHWW010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.132"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            106..1305
                     /locus_tag="U2R64_002824"
     CDS             106..1305
                     /locus_tag="U2R64_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEM8919568.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1332..2600)
                     /locus_tag="U2R64_002825"
     CDS             complement(1332..2600)
                     /locus_tag="U2R64_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEM8919569.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            2693..4032
                     /locus_tag="U2R64_002826"
     CDS             join(2693..3134,3134..4032)
                     /locus_tag="U2R64_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HEM8919570.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT         1374 a          755 c          712 g         1193 t
ORIGIN      
        1 aaaacatctt tccatcggaa agatgttttt ttgctttttc tagtttaaat aacagctttt
       61 ttcatctatt ttcgttatac tgtataagaa aaaggagttg aatttatgaa tctaaccaga
      121 gatctgatct ttttagttct ctatcttatt ggggtattct ctatcgttta ttggcgaaaa
      181 cagaagaagg atccttcctt gttcttttac ggcagtacgt ggacatttac ggtaatctta
      241 acttattttg tcgtgttgga aattttttat tcgacctttt attttttgat tccattgttg
      301 ttctttagta tctttgcttt ttcttatttc acagaaaaac gaaggctact gaatggtctt
      361 ttattcaatg ttttactcat cagtttcggc atctacttgt ttgtcttgct gtatgaaacg
      421 caaaatattt ttcttggcgg actgatcgcc ttgatcacga ttccattgct acttgtcctt
      481 ttatttggta tttatggatt gattgttttt cttttttgga acggggtcac agttttacgt
      541 agagaatcgc attcattagc taatctttta acgttgatac tagccatttt tcttacactg
      601 tttcttgttt ttgacttttt cttgttaaaa tatttgccgc aatggataaa tgctttgttt
      661 ttctgcgttc ccctgatctt gatctatcta tttatcgtat tctacaactt tttgactgtc
      721 tcattcttgt atcagttcaa ccggcctcga tacaatcaag acttcatcgt tgtgttaggc
      781 gctggattga tcaatggaga aacagtttct cctcttctag ccaagcgaat caataaggca
      841 attgcttttt atcgggctca aagccgtgct acattaaatc cgcccatctt attgatgtct
      901 ggcgggcaag gagcagacga aaaagtacca gaggccattg cgatgaaaca atatgccatg
      961 gaacaaggaa tccctgaaag agacattctt gtcgaaacca attcgacaac cactttggaa
     1021 aacatgctct attcaaagga aatcatggat cagcaaatga aagggccata ccgcgcgatc
     1081 tttagttcca acaattacca catttttaga gccggtcttt atgcgcggca agccaaattg
     1141 aaagcaaatg gtattggtgc aaaaacagct ttctactact tgcctaatgc gtttttaaga
     1201 gaatacctcg ccatcttgat gatgaacaaa aaaagacata tgatcatttg cggattgctt
     1261 ttcgcaggct ccgcattctt atcgctgatt actttacttt tctaaaaaaa caaggtgtga
     1321 caaaacatat gtcacacctt gtttttttct ttcattctct taactattgg caaaaagagt
     1381 atcccttttt tgaccgctac ttgctgagca gaataaatac cgctgttgcc tgaacacata
     1441 aagctgatca agcagatcat aaagaagtat actgccgctt gtgaaccgaa caattcgatc
     1501 cccatcacaa agcaggcaat cggtgtattt gtcgcaccag aaaatactcc gataaagccc
     1561 aatcctgcaa gaaaaggaac agaaacatgg agcaaaggcg ctagtgctgc accaagcgtt
     1621 gcaccaattt caaacaatgg tgtcacttct cccccttgat atcccgcgcc taaagacaaa
     1681 actgtgaaga ataacttccc aataaaatca tagacatgtg cctgtccatt aaatgattct
     1741 tgaagtaacg gaagactcaa tccgagataa cgttgtgttt gcaaaatcaa tgctgctgcc
     1801 acaactacag ctccacctat cgtatttcga caaacaggat gaggaatcca ttgtgcatat
     1861 cgcgctttta aaaagacgat cgaacggctg aatacccaac caatcaaacc aaaagcaatc
     1921 ccagcaacaa aaactttgaa gaacagcaac atactccatt caggaatcac acccatttgg
     1981 taatgtagat gagaaacacc atagctttct gtcatgaaat ttgcaaacag tgcagcaaag
     2041 aagctaggga agatcgcttc tgttcggact ttcccgattg ccaacacttc taatccaaat
     2101 aatgttccag ctaaaggtgt gccaaataca gaactaaaac ccgcactgat tccactgata
     2161 atcaagattt cccgttctga tttatccaat cggaacaaac gtgccgtatt atctgctaac
     2221 gctcccccca tttggactgc tgttccttca cggccaacag atcccccaaa taaatgggta
     2281 gttatggttc caaacagtgt aagtggaata agccgcaacg ggattttttc ttctccacca
     2341 tttccttgat cgatcactaa gttgtttcca cgactagaaa gtccgccgtg atacgcatag
     2401 agataagcaa aaagcgcacc actaactggt agtagacaaa ggagccaagg atgtgatagt
     2461 cggatatctg tcacaactgt caggctattt aagaaaaaag cagacaagct ccccatgaat
     2521 ataccgagaa tcgctgtgat caccagccac ttcagcatat acactaaaat gcgtactgga
     2581 ctcggtaatt gtttttccat aaaaaattcc tcctcaataa aaaaacgcct actaaagaat
     2641 gatgtgcacc ccaaaagtta gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa
     2701 atatacattt gtttttaaga aaaaagtagt ttcagactat ttaaataacg aaggcggcta
     2761 caaatatctt gcacataaat atcaaataaa tcgtacactg gttagacatt gggtaaggat
     2821 ttataactat catggttggg aaggcttggt tggaggtggc aaaagctaca ctacaaaatt
     2881 taaacttgat gttatagaat atatggaaac aaatggtctt tctatccaag aaactgctaa
     2941 aaaatttaat atcggttcaa atagaactct aagtaaatgg atagagcaat atgaagaagg
     3001 cggtgcttct tcacttgaga gccaaaaaag gggcagaaaa attagtatga attccaagct
     3061 aaacattcct aaaaaactta aagatgagtc tcttgaagaa gaagttattc gtttaagagc
     3121 agagaacgca tatttaaaaa agttagaaac cttgattcaa gaacaagatt tgagcaagaa
     3181 gaaatcaagg ttaaaacaat ccttcagctc aaaaaagaat ttaaattgaa tctattactt
     3241 tcaattgcac aattagcgaa gtcaacttat tattactggg taaaaaaatt agataagcca
     3301 gataaatata gcaagataaa gcaagaaatt acagcgattg taaaagaatc aagaaactct
     3361 tatggttatc gtagagtcac tttagcgtta aagatgaaag gatatacaat caatcataaa
     3421 acagttagaa aattaatgtc ccaaatggga cttacctgtc aaatccgaat aaagcgatat
     3481 aaatcttata aaggaacagt aggaaaaatt gccaagaatg tgttaaaacg aaatttttca
     3541 gtagatacac ccaataaaaa atgggtgaca gacgtcactg aattcaagat aaaaggaaga
     3601 aaaatctatc tatctcctat acttgattta tttaacggag aaataattag ttatagtata
     3661 tcaactagtc caacatataa actgattgaa gaaatgcttc aacaagcaat taaaaaaaag
     3721 ggaactgagg gttcactgat tctacattca gatcaaggat ggcagtatca gatgccacaa
     3781 tatcaaaaaa aattaaaaga gaataacatt attcaaagca tgtctagaaa aggaaattgc
     3841 ttagataatt ctgtaataga aaattttttt ggtgtgctta aatcagagtt tttttatcga
     3901 gaaaaattcc gatcaattga gatatttcaa agtaaattaa atgagtatat taggtggtat
     3961 aataacaaaa ggataaaact aaagttaaat ggactatctc cagtagaata tcggaaacag
     4021 tccattaaat agtt
//
LOCUS       DASHWW010000129         3995 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.133, whole genome shotgun sequence.
ACCESSION   DASHWW010000129 DASHWW010000000
VERSION     DASHWW010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.133"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="U2R64_002827"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="U2R64_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEM8919571.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="U2R64_002828"
     CDS             complement(3250..3768)
                     /locus_tag="U2R64_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEM8919572.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1293 a          651 c          606 g         1445 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgc
//
LOCUS       DASHWW010000130         3763 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.134, whole genome shotgun sequence.
ACCESSION   DASHWW010000130 DASHWW010000000
VERSION     DASHWW010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.134"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(75..1073)
                     /locus_tag="U2R64_002829"
     CDS             complement(75..1073)
                     /locus_tag="U2R64_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HEM8919573.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="U2R64_002830"
     CDS             complement(1148..1444)
                     /locus_tag="U2R64_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEM8919574.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="U2R64_002831"
     CDS             complement(1437..1730)
                     /locus_tag="U2R64_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919575.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="U2R64_002832"
     CDS             complement(1876..2427)
                     /locus_tag="U2R64_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HEM8919576.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="U2R64_002833"
     CDS             complement(2601..2900)
                     /locus_tag="U2R64_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HEM8919577.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="U2R64_002834"
     CDS             complement(2927..3235)
                     /locus_tag="U2R64_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEM8919578.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
     gene            3540..>3763
                     /locus_tag="U2R64_002835"
     CDS             3540..>3763
                     /locus_tag="U2R64_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HEM8919579.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNG"
BASE COUNT         1116 a          729 c          529 g         1389 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc gtggtgctag
     3421 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3481 tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat ggttacgtcg
     3541 tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat atccccgatt
     3601 atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat cgtgttttaa
     3661 aaggcatcga aatcggttac atcgcttctg aaaaggatcg gatcatcgac tatttagccg
     3721 ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgg
//
LOCUS       DASHWW010000131         3735 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.135, whole genome shotgun sequence.
ACCESSION   DASHWW010000131 DASHWW010000000
VERSION     DASHWW010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.135"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            7..474
                     /locus_tag="U2R64_002836"
     CDS             7..474
                     /locus_tag="U2R64_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919580.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            679..2343
                     /gene="alsS"
                     /locus_tag="U2R64_002837"
     CDS             679..2343
                     /gene="alsS"
                     /locus_tag="U2R64_002837"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HEM8919581.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2356..3066
                     /gene="budA"
                     /locus_tag="U2R64_002838"
     CDS             2356..3066
                     /gene="budA"
                     /locus_tag="U2R64_002838"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEM8919582.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3196..3693
                     /locus_tag="U2R64_002839"
     CDS             3196..3693
                     /locus_tag="U2R64_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEM8919583.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         1233 a          595 c          806 g         1101 t
ORIGIN      
        1 atcgtgatga taggtatgac agaagaatta gcaaaagaaa aaagtttttc accagtacgt
       61 ttgttcataa agacgtttcg ccaattttgg ctaaagggat ttttttattg gctatttgct
      121 tggatagtta gtgtgataat gatttttgat tgtttctttt ttatacgttt ttcttatgga
      181 aaatggttga ttccgttgtt tgttttactt gcttgtttat cagtttcctt tagcatcaac
      241 tactggtatt ttcaggtgag aaatccagcg tcgaaaccaa atcaagttct acggatagcg
      301 ttctactata cgttgaaaaa atggtatgtg agtttactag attttttact attgacaagt
      361 ttgtttctct tctttttcgt aaagccccaa tggtgtattc tactaggtcc ttctatcgta
      421 tttggtttga tttacttcaa caatcgtaaa ttgatgagaa ctatggatct gtagacttta
      481 taaattgaaa ctttcaatta agaatgacag tttttatgta aaaactgtca ttctttttca
      541 ttttttgaaa catatggcta aacaaatgaa ataaaacgtg ctatactttt gaatgaaaca
      601 ggtttagaaa ctgtatcaat tatttgtgat tatttctaac taataattaa aaataaagca
      661 taaaaaggac gatgttcaat ggacgaaaaa atgaaacaag gttcgaaatc tgtagtagaa
      721 agtttgatta atcatcatgt tgattatgta ttcggtatac caggtgcaaa aatcgatggt
      781 gtatttaatg aattagagga tcaaggtcct gaattaatcg tgactcgtca cgaacaaaat
      841 gctgcattta tggcacaagc aatcggacgt attacaggag agccaggagt agttatcgca
      901 acaagtggtc ctggtgctag taacttagct acaggtttgg taacagcgac agcagaaggt
      961 gacccagttt tagcaattgc cggacaagta aaacgaagcg atctattgaa gttgacccat
     1021 caaagcatgg ataatgcagc actgttccag ccaatcacaa aatacagtgc agaaatccaa
     1081 gatccagaaa caatttcaga agtgattgcc aatgcttatc gtatggctaa gagttcaaaa
     1141 aaaggcgcga gctttatcag tatcccgcaa gatgtagtgg atgcacctgt ccaagggaat
     1201 gtcatcaagc cattgagcga tcctaaatta ggttctgctt ctgcagatga tatccgttac
     1261 ctagctgaac gcattagaga agcaaaacta ccggtactat tagtaggtat gcgaggatca
     1321 agtgaaaaag aaacgttagc catcaggcaa ttagttggaa agacagcatt gcctgttgta
     1381 gagacattcc aagcagctgg agtgatctca cgtgaattag aagcgcattt ctttggtcgt
     1441 gtgggtttat ttagaaacca accaggagat atgcttttga aacgaagtga tctagttatt
     1501 gctattggct atgatccaat cgaatatgaa gcaagaaact ggaatgcgga aaaagatgcg
     1561 cggatcattg tgatcgatga agcgccagct gaaatcgatc cttttatgca gcctgaaaga
     1621 gaattgatcg gtgatatctc agccactctt gatttattga caggttcatt agagcctcaa
     1681 caagtgtcag aagatgcaaa agaatattta gcatctcttc aagcagaatt aacggagcgg
     1741 gacattgttc aatcaaaagg agaagcaggt atcttgcatc ctttagaagt tattaacacg
     1801 cttcagtcaa aagtaacaga tgatatgact gttaccgtag atgtaggtag tcattatatt
     1861 tggatggcac gccactttag aagttatgaa cctcgtcatt tgttattcag taatggtatg
     1921 caaacgcttg gtgttgcatt gccatgggcg atttctgctg cattggtgcg tccaaataca
     1981 caaatcgtat cagtttccgg cgatggggga tttttattct ctgcccagga tttagaaacg
     2041 gcggtacgta aaaaattgaa tatcgttcat ttgatttgga atgatggaca ctacaatatg
     2101 gtagagttcc aagaaaaaat gaaatatcag cgggcgtcag gtgtagactt tggtccagtt
     2161 gattttgtga aatatgcaga agcttttggc gctaaaggaa tccgagctac aagtgtagag
     2221 gaattagaaa aagctttaga agaaggattt gcgacagaag gacccgtaat tattgatatt
     2281 ccgattgatt accgtgataa tgagaaattg ggagaaacaa tcttaccaga tcaattctat
     2341 taaggaagtg tcgacatgac tgaaaaaatc ttataccagc acgggacatt aggagctttg
     2401 atggctggct tgatggatgg aacagaaacg attgctcata tattagaaaa aggaactctg
     2461 ggattgggaa cattgcatgg gcttgatggt gaagtcatct ttttagatgg cgtagcttat
     2521 caaggaagat cagatggctc agttgcccaa ttagatggaa gtgaacttac cccctatgca
     2581 gcaattacag attttacgcc agatactagt ttttctgtct caaaaactgc agatggagaa
     2641 caattgaaaa aagacatatt agtaagagaa gccggggaaa acctattttt ggcagtgaag
     2701 ataactggat tattcaaaaa tatgcacatc cgtatcatgc cgaagcaaga aaaaccttac
     2761 agaagactag caaaaatttc agagtctcaa ccagaattcc aacaaagcaa tgtccaagga
     2821 acattagtcg ggttctttac gcctgaatta ttccaaggag ttgctgcagc gggatttcac
     2881 ttgcatttta tcgatgatac acatacattt ggcggacatg taatggattt tgaagtggct
     2941 gaaggaaaag ttgagattag ccgcatctcg tcccttgtac agcattttcc agttgatgat
     3001 ccgacttttg ttcacgaaac gattgattat gctgatttag cagcagaaat ccaacaagca
     3061 gaatagaaaa agacagcgag atgcgttcaa ggtgattaac ctgacgtatc tcgttttttt
     3121 gaggaggaaa cctagcgttt acaaaaaaac tgagctataa tcttctccat agatcaaaaa
     3181 ggagcggttt ttatcatgtg gacagaaaaa cagaaaaaag atgcatacga aattttatta
     3241 ttacagcaac aaggattatt agaagcagaa gataactggt tagcaaattt agcaaattca
     3301 tctgcattgt tgaatgagac tttgcctgag actgtctttg caggatatta tttattcgat
     3361 ggtaatgaat tgattttagg accgttccaa gggcgagttt cttgcacacg tatcaagatg
     3421 ggaaaaggag tttgtggaga atcagctgaa aaacaagaaa cattgatcgt tgatgatgtc
     3481 aaaacccatg caaattacat ttcctgcgat tcagccgcac aatcagaaat cgtagtgcca
     3541 atggtaaaag aaggtaattt aatcggtgtt ttagatatcg attgcggagt aacgaaaggg
     3601 tatgatgaaa tcgatcaagc atttctagaa aaatatgtag atcttttatt agcaaatttt
     3661 aatataaatg ctttttcatt tattaataac taaaatcgtc tattgaaaca aaaaagaaga
     3721 gaaatcaaga ataaa
//
LOCUS       DASHWW010000132         3705 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.136, whole genome shotgun sequence.
ACCESSION   DASHWW010000132 DASHWW010000000
VERSION     DASHWW010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.136"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..543
                     /locus_tag="U2R64_002840"
     CDS             <1..543
                     /locus_tag="U2R64_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8919584.1"
                     /translation="GKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDP
                     IEARLTYNDGSAQVIDKSTGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQ
                     LIFTAKTPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTIL
                     AVSLLLLVLATFGYAVLKFN"
     gene            complement(579..2636)
                     /locus_tag="U2R64_002841"
     CDS             complement(579..2636)
                     /locus_tag="U2R64_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEM8919585.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(2780..2971)
                     /locus_tag="U2R64_002842"
     CDS             complement(2780..2971)
                     /locus_tag="U2R64_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919586.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            3159..3614
                     /locus_tag="U2R64_002843"
     CDS             3159..3614
                     /locus_tag="U2R64_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919587.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            3611..>3705
                     /locus_tag="U2R64_002844"
     CDS             3611..>3705
                     /locus_tag="U2R64_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HEM8919588.1"
                     /translation="MIASLFIYPEGGITVAKAKTPFEKAASKILER"
BASE COUNT         1138 a          622 c          729 g         1216 t
ORIGIN      
        1 ggtaagaagg gtacgccgac agctccttta aacgcaggat ctgaagtaca atatctagtc
       61 acacaaaaat ggcacacaaa aggcgtagac gctgcgtcag atcactacaa acaatttagt
      121 attcaagatc caattgaagc tcgtttgaca tataatgacg gttctgcgca agtaatagat
      181 aagagtacag gaaaagatat tacttctgaa ggcacactaa cctatgatag caattcaaga
      241 acgctgaagt gggaagcttc cgctgacttc ttaaataaca atcttttaga tggacgagaa
      301 attcagctga tatttacagc taaaactcca ttacaatcag aaaaaaatat tgataaccaa
      361 gccgtagtag cagtagataa tgtttctaat aaaacaaatg ttgtgacaat tggggttgat
      421 cctaacttgc cacaagttat tgttcctaaa acaggttcta cacatttagt aacgatttta
      481 gcggtcagct tactattact tgtgttagca acttttggct acgcagttct gaagttcaat
      541 taaacaaaaa aacaaggctg aaaatcagcc ttgtttttct atttgaaaat gggattggca
      601 ctaataaata cgttgtctga agaaagtgat ccgtctgcag aaacttcata agcatgggat
      661 aaaccaacga tactttgatt gttgtaaagc aagtttgcgt tatgagcagc gctatctttc
      721 cacataacca tagcatttac tgctcctgta tctgaaagga tctcgtcaac gtaaaggtag
      781 aaactattga tattttctcc tttagcaccg tagcagccta agctttctaa gagatcttgg
      841 aaagtaccgc cgccaggtcg gtaatgactg aagcttactt gtaattcttt tgcacgaata
      901 tctgcagctt gttgaacgat atcattgaat tgcattgggg caacgccatt ttgttgacgg
      961 tagctattta accaagcaag ttctttttga cgcacatagt tgtttaaatc acttagtgag
     1021 atatttttgt atttgaaagt gatcgttcga ttttggtcaa cattattgat tacacgttgt
     1081 ccatttttat caacggtaac agatgaatcg tcatttctac acaagaagta gttttgatcg
     1141 gtcatatttt tccaagaagt agagaaacta tctccctcgt aaaccgtttg tgtttcagta
     1201 gataaaacag cgtttgtgtc aacgtttata tggttcacag tgacgttgta ttgatgagta
     1261 taggcaaaat tgattccttg attacttgta acgttgttta aagtcacagt gttgctagag
     1321 ctttctctag gatcaagaac aaaattagtg aacataggtg cttcaattgt gatgctttgt
     1381 ccataaacga cgggataact cttactgtaa ttatagagtt cttggatatt tggatcagta
     1441 tccgagactt tatttggacg agctttcact tcaactagaa agacttcatc atagtaaaaa
     1501 gtaaatgtgg tatttgtgtt aatcgtttgt gtttgtgttt cattcccatt tacttgatac
     1561 tgtggtgctt caaagttagt caagtcggtt ctagcttttg cagtgtaact tgtaccagct
     1621 tttactgaga catgttcttc ttttagcagc gttccagttt gtcgattcat atgacggaca
     1681 gttaccgcat attctgaagg tttaggtttg tgttgtaacc ctttaaatgc agaatcaaga
     1741 ctatttttag cattatttac ttgggtttga gaagctttag aatcgtctag tactttttta
     1801 gcattggata aagcagtctg aaaattattc caagatcctt ctgtaaaatc tcctttagca
     1861 gttgatttta cttggttgta caaggcttgt aattccgttt tgttcacagt aggagctggt
     1921 tttttcttta atcccttgta agcagaatct aatgtgtttt tggcactatc cacttgtttt
     1981 tgagtcgctt ttgagtcatt taacactttt ttagcattgt ttaaagcggt ttggaatgcg
     2041 ttccaggtat tgtcggtata gtcacctttt ttagttccct taacgctcgt ataaagagct
     2101 tctaaagctg atttattcac tttgggttta gaggtgtcag caccatacca accaatacct
     2161 tcgtatttcc agccatagtc tttggttaac cattgtactt ctttccaact tgcagtgtag
     2221 tgatgcgaac cagaggtaac acctggaagg aaaaggcggt agatcggttt attatttttt
     2281 tcggcagaac gccatgcagg cccttcataa gtccaaccgt aatttttggt caaccatttc
     2341 acttcatccc aactagctgt gtaatggtga tcacgaaggc ctttattgta taaacgatag
     2401 acaaggtggc caccgctagt cggtgcttcc caagcggggc cttcataatt accccactta
     2461 attttcacta ggtgatcacg ttcttttgtg ctagaggtgt aaaaatgttc atggttattt
     2521 ggattataaa ggcgatacat gacgttagtt gaagcagcgt cagcagatcc agcaagagca
     2581 actgtggcag caaatgttcc aatagctata acagtttttg ggtttaataa tttcatgttt
     2641 tcaactccta ttaaatgatt aaatattttg tttacattca taatatacca cggtataccg
     2701 aggtagtcaa cggtataccg tggaaatttt gaaataaaaa agccgcccta tgaagagtgt
     2761 aaggatggct gtttatatgc tatgaagaaa tggattcggc gtatttggtt agtttggcag
     2821 cattatcaaa tcgcattttt tcaatcgcac tttttttctt tattaaatcc gcaattgttg
     2881 attctgcgac tgaagaatgt ttgctaattt catatgctgt cttgccagtt tcaaatagta
     2941 accattcgat tttctcttta tcagcgtaca ttgcaatgct ccctcttgat tttttcttta
     3001 ttatagctct tttttgtaat aaatcacaat atcaagagga aaagtttcta tagaaaggtg
     3061 ggaaattatg agtatccgtt ccccgtgtat caaaatgagg tttgttgcta ctttcgttat
     3121 ttgatatact aaaataaaac aacgaaagaa ggaatagaat gaaaaagtta ataatggtat
     3181 ttacttcgtt gattgccatg attgttattt taggtggatg tggtagtgaa aaaaataagc
     3241 aagatagtca agataatggc gtgttaaaac caggaacagt gtggaaagaa gaagtaggcg
     3301 gacttgttca taatttaaaa attatagatg atacaacatg ggaatattcc gaaagtgttt
     3361 ggcatcctga acaagtacaa ataacagttg agaagctaaa agactataaa ggattagaaa
     3421 gatataaggt aatcgattca ggtggagtag atttattcat aggtaaaaca gccttaatag
     3481 ttccctataa caaagacggt ttagaaacgt ttaaatttat tccaacaaac gaaaaagaac
     3541 atcgagataa aagtgaaata ttaaaagaat acagtactaa atctggatac aagttacaaa
     3601 agactagcga gtgattgcta gtctttttat ttatcctgaa ggaggaatca cagtggcaaa
     3661 agctaaaacg ccatttgaaa aagccgcgtc taaaatctta gaacg
//
LOCUS       DASHWW010000133         3455 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.137, whole genome shotgun sequence.
ACCESSION   DASHWW010000133 DASHWW010000000
VERSION     DASHWW010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.137"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(578..1594)
                     /gene="tsaD"
                     /locus_tag="U2R64_002845"
     CDS             complement(578..1594)
                     /gene="tsaD"
                     /locus_tag="U2R64_002845"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEM8919589.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(1591..2055)
                     /gene="rimI"
                     /locus_tag="U2R64_002846"
     CDS             complement(1591..2055)
                     /gene="rimI"
                     /locus_tag="U2R64_002846"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEM8919590.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2062..2604)
                     /gene="rimI"
                     /locus_tag="U2R64_002847"
     CDS             complement(2062..2604)
                     /gene="rimI"
                     /locus_tag="U2R64_002847"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEM8919591.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(2588..3310)
                     /gene="tsaB"
                     /locus_tag="U2R64_002848"
     CDS             complement(2588..3310)
                     /gene="tsaB"
                     /locus_tag="U2R64_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEM8919592.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
BASE COUNT          984 a          757 c          594 g         1120 t
ORIGIN      
        1 atatcagggt cactgcttat tttcctccct aaaacttctg aaagatccgg cagttttaga
       61 tcactggaca agactcaaag attttctatg tgtgtttcag ttatgtaata ttcactgttt
      121 gcaaaaaata ctgttagatt aactagatga agcgtcttgt cctcatccga tctagattat
      181 tcgatattcc tcgacaataa acgattactc agtgagggca atcagaggaa cggataatga
      241 taaataagct gtaaaaaata gcaaaataac aataatgatt aaaagtatgt aaaaaatagg
      301 gctttgacaa aaacgtgtca cagccctatt tcgattaaac ggtgtgtacc tgtcaactct
      361 tcggtcacaa gtcataatgt tcataaacat gaggagctgt tttttgaaat tgttccttgt
      421 gaatcagagt taaacgacag gcttacgaac tcttgattaa acggcgttca aaagcttgca
      481 tacgcggtaa taagaacagc caggtcaaaa acatgagaag ccgtttttcc tgggctgttc
      541 ttattacttg atgcagggca gctttttcac aacctcttta ttcagataaa accaagcttg
      601 gatcagcatt caactgatag ctagcaaaat ttcttttttg catttccaca tgtgctgctg
      661 ctccaatcat tgcagcatta tctccacaaa gtcgaagagg gggaatcact agttctacct
      721 cagggagttt agttgccaaa gcatcctgca atccttcacg caacccttga ttggccgcta
      781 cacctccagc tataatcagt tgcttgactg gataattttg acaagctcga agtgttttag
      841 taatcaatac atcgatcaca cttgcttgaa agctagctgc taaatcattt ttgtctagat
      901 cttctccacg ctgttgtgca ttatgcacca aattgataaa tgcacttttt aatccgctaa
      961 aactgaaatc ataattatct tcatggatca tcgctcgcgg aaaatggtaa ttatcttttc
     1021 cctgatgagc tagctgatcg atttcttttc cgcttgggta agaaagacct aatactcttc
     1081 caactttgtc ataagcttct cctgctgcgt catctcttgt ctccccaatg atttcatatg
     1141 atccatcttc ttgcatatag actaattctg tatgtcctcc gctaacaaga agtgccatca
     1201 atggaaactg gaatggttta accagacggg ctgcatagat atgccctgcc atatggttta
     1261 caggaataag cggcaattgg tgtgcccaag caaaagcctt agctgcagaa ataccaatca
     1321 gcaacgagcc gacaagtcct ggtccataag tgacagcgac tgccgataaa tcttctgccg
     1381 acacaccagc ttctaccagt gcatcttcca agcataaggt gatttgttct acgtgatggc
     1441 ggctagctac ttcaggtact acgccaccaa aacgtttatg actgtttatt tgagaagcaa
     1501 cgatgttaga taagatctct gttccatttc taacgaccgc tacactcgtt tcatcacaac
     1561 ttgattcaat cgccagaatc aattcttcat tcatttcatc gtctccgttt ttaactttct
     1621 gctcataatg atcgcatctt ccgtcggatt gcgataatat gatttccgtt tacctaatat
     1681 acgaaacttt tctgattcat aaagttttct tgctgcttca ttagatagac gtacttctaa
     1741 aaaaacatgc agcgaatctt ttatttgttc cgtaatcagt aattgtaaca aatgccgtgc
     1801 atgccctttt ccttgttctg aaactgcaac agcaatattt gtgatctcga cttcatctat
     1861 tactttcgag tatccaataa agccacagat ctggttatct tcagctaaaa gcagataatc
     1921 agagtgaggc tgttggatgt ctgccaaaaa ctgcattttc gtccaaggtg aaccatgtgg
     1981 ataagcattt tcgctaatca tccatacgca ttctgccaag tacgcttcat caaaatcttt
     2041 ttttctgcaa atcaactaat ctcactcatt ttctaaaagt tttatcatat ccaacgcatc
     2101 ttcttttgtt tcagtgtaat atcttttttt gatcgttgtt gcttgaaacc ccaatttccg
     2161 ataaagtctt tgtgcatctt gattactcat acgcacttct aatgacatcg tctcacagcg
     2221 attcattata gcaaagttct cgatttcgtc aataagcagc gaaccgattc gtttacgctg
     2281 atatgccggt cgaacggcaa tattcgtgat atggcaatct aaaccgaacg ctcttgaacc
     2341 gataaaacca atcattcttc cattatcaaa gatacctaga tatagatgag gaagcggtga
     2401 cttcaattct gatataaagg cactttttgt ccatggcaat tcgccattat agacttctcg
     2461 ttcgacatcc agcagctctt tgatatcttc tgtagtcaat tctcttagta cgtaacgacg
     2521 atcgatttgt tcgactgttt tttctgtata aatcatttta tcttgaaaaa agcttctggc
     2581 atacgctcta aattttttca acataacttt cgtctccagg tgtgtgcgtc tccaaccatt
     2641 tttcttctgc ttctactcgt tttaaatagc gaggaagaaa agcttgtttc tctgcaactg
     2701 gttcaactaa agcacctaat tgagccacag ttacaccact tggaatatcc catgctggaa
     2761 ctgtattaat catcgcacta ggcaatattt cctttatttc agagaagaat ttgtgacaat
     2821 cactcccgac gaaataaata gcttcattca gcttttgtag ttgtgtgaac aaatcagaag
     2881 cagaaatatg tacatcttca agtacagttt ctaatctatt ttctttccag cggtatgccc
     2941 cagcgtatac attttttctt cgagcatcaa acatgggcac aataatatta tccacaccga
     3001 tgcaattagc cgcgatggtt ttcagactag atactcctac tagctcttta tctaatgtat
     3061 aagcaatcgt ttttgctgtc gttacaccta tacgaagccc tgtataagaa ccgggaccat
     3121 cagaaaccgc gattcggtca atgtcttttg gacttatttg aagatctgca aacaattggt
     3181 cgattgcagg catcagtgtt acactgtggt tgcgtttgat atttgtttgt atttgtccaa
     3241 gaatttgttc gtcttctacc acaccgatcg ccaaagtttg gtttgcagta tctattccta
     3301 atgtaatcat atatttgatc ctttctgcta tgacattctc gccttccatt gtagcatact
     3361 tttttattct gaggatgaaa ataccaaagg caaaactagt acaataatac atgattatct
     3421 gctggcgggc aaattttgcc ccttcctgaa acaca
//
LOCUS       DASHWW010000134         3448 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.138, whole genome shotgun sequence.
ACCESSION   DASHWW010000134 DASHWW010000000
VERSION     DASHWW010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.138"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            115..975
                     /locus_tag="U2R64_002849"
     CDS             115..975
                     /locus_tag="U2R64_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HEM8919593.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            987..1814
                     /gene="panB"
                     /locus_tag="U2R64_002850"
     CDS             987..1814
                     /gene="panB"
                     /locus_tag="U2R64_002850"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HEM8919594.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1829..2677
                     /locus_tag="U2R64_002851"
     CDS             1829..2677
                     /locus_tag="U2R64_002851"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HEM8919595.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2687..3082
                     /locus_tag="U2R64_002852"
     CDS             2687..3082
                     /locus_tag="U2R64_002852"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HEM8919596.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            3284..>3448
                     /locus_tag="U2R64_002853"
     CDS             3284..>3448
                     /locus_tag="U2R64_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8919597.1"
                     /translation="MSRRQRRTYSKEFKQQIVNLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQSTGSFK"
BASE COUNT         1336 a          375 c          686 g         1051 t
ORIGIN      
        1 atattatgat aaattaacta tggatgatat ttgaaaaaaa catactgtat atttgattta
       61 atttttattt ttaagctcat atcgtaagaa tgggacttgt agtctcactt ctttatggag
      121 gtgataatta tgaacgttgg ttttattgga gccggcaagg taggttgttc attcgggaag
      181 tatttccagg aacataaaat acaagtaaca ggattttata gtaaaagcga agactcgtca
      241 ttagcagctt cgaattttac atctagtaaa caatatttaa acttaagaga attagtagat
      301 gaaaatgata ctattttcat tacgactcct gatggtcaaa ttcaggaggt atggcaagaa
      361 attaaaaatt atcaaatcaa aaacaaatta atctgccatt gcagtggtgc aatatcttca
      421 gatatctttt caaatataca ggactatggt gcttatggct attctgtcca tcctatgttt
      481 tcaatatcag ataaatataa ttcatacaaa aaattaaaaa aatcttttat aacaattgaa
      541 ggcgatgaaa aatatgcaaa gtttttatgt gatttcttca aaaagttagg taatagtact
      601 gtaattgtat ctaaggagaa taaatctctt tatcatgccg catcagtagt atctagtaac
      661 cttgtgctag gacttattaa tacaagcgtt acatatctaa ttcaatgtgg atttactgaa
      721 aaaatggcaa ttgaagcttt atatccatta attgaattta atattagaaa tataaaagaa
      781 aaaggaatta tagaaagttt gacagggcca gttgaacgtt gtgatatttc aacaattaaa
      841 ggtcactgtg aagttttatc agatgaagac agagctttat atatgctatt atcaaaaaat
      901 gtattagaga tagctatgtt aaaaaatatt aatagagatt atagtgaatt agaaaagtat
      961 ttaggagaga gttaggagag aaatagatga aaaatacagc agttacattt aaagaatcta
     1021 aattaagaaa tgaaaaatta acaatgctta cagcttatga ctattcaaca gcaaaaataa
     1081 ttgatgaagc tgggataaat ggaatattag taggagattc tcttggtatg gtatgtctag
     1141 gacatgaaga tacactttca gtaacaatgg aagacatgat tcatcatact agagcagtta
     1201 caagaggagc taagaacact ttagttgttg cagatatgcc atttatgtct tatcaaactt
     1261 cagtatatga ttcagtagtt aatgcaggaa gattaataaa agaaggacga gctcaggttg
     1321 ttaaattaga aggagggata gaagtatgcg ataaaataga ggctatagta aaggcttcta
     1381 tacctgttat ggcgcatata ggtttaacac ctcaatctgt taatgcattt ggaggattta
     1441 aggtacaagg aaaggacaag gaagctgcta aagaattaat aagagctgct aaagctgtag
     1501 aaaaagcagg agcattcgct gtagtgttag aatgtgttcc aactaagctt gcagagttaa
     1561 tttctaaaga gatatcaata cctacaattg gtattggagc aggtgcaggg tgtgatggac
     1621 aaattcttgt atatcaagat atgttgggga tgtatagtga ttttacccct aaatttgtga
     1681 agaaatatgc taatttatca gaagagatga ataaagcatt tacaaaatat atagaggaag
     1741 taaaagatgg agtttttcca ggtccagaac atgggtttaa aataagtgat gatgttttag
     1801 aaaaattata ttaaaagggt caagaaatat ggttatattt aaaacagtga atgatgttag
     1861 aagtcaagta aaagagtgga aaaaacaagg cttaaaggta ggattagttc ctactatggg
     1921 atatttacat gaaggtcatg aaagtttaat tagaaaagca tcaaaagaaa atgataaagt
     1981 tgttgtaagt atctttgtaa atccaactca gtttgggaaa aatgaagatt taggtagtta
     2041 tccaagagac ttagaaagag atatagaagt atgcacaaga ggtagagcaa cagcaatatt
     2101 taatcctgaa gttgaagaga tgtattgtga caatgcaagt acttttgtta atataactgg
     2161 attaacagaa ggtttatgtg gagctagtag gccaatacat tttagagggg tttgcactgt
     2221 tgtaagtaaa ttatttaaca taataccagc agatagagct tattttggag aaaaggatgc
     2281 acaacagtta gctgtaatta aaagaatggt tagggacctt aatattgata tagacgttgt
     2341 agggtgtcca attataaggg aagaggatgg actagctaaa agttctagaa acacatactt
     2401 aagtttagag gaaagatctt cagctactat tttaaataaa tctttaactt tagctaagga
     2461 agctttaaat aatggagaga gagacagctt aaaaataatt gagataataa gtaaaaatat
     2521 aaatacttat aatttggcaa agattgatta tgtagaagtt gttgattctt tatcattaca
     2581 aagagtaaat tatattgaaa aatcagtttt agttgcaata gcagtattta taggaaaaac
     2641 aagattaata gataatttta catttgaatt acaatagggg gctataatga aagttacaat
     2701 gttaaaagga aaaatacata gagctacagt tgaacaagct gagttagatt atgtaggaag
     2761 tattactgtt gatatgaatt tattagaagc agcaggaata tatgaatatg aaaaagtaca
     2821 aatagttgat gttaataatg gaaatagatt tgaaacttat acaatagctg gagagagagg
     2881 aacagggatg atttgcttga atggagctgc agctagatgt gtatcaactg gagataaaat
     2941 aattttaatg gcatattgtg aattaaatga aaatgaggtt aaggatcata gacctaaggt
     3001 tgtttttgtc gatgataata ataaagttga aagagtaaca tcatatgaaa aacatggaag
     3061 gttatcagat ataattcttt aggttttgta atgttattta tatatagcta gactattatt
     3121 gaaatattta ttgattacta attggataga tgtcaataaa gtagacacaa aaagagaaga
     3181 tacagactgt agacaaagtc cattttatgt gaatcggcta cactagacta gacagaaaaa
     3241 ataaggtgtg tagaataata aaaaacacac tggaggattt ttcatgtcaa gacgtcaacg
     3301 aagaacctat tcaaaagaat tcaaacaaca aatcgtcaat ctctatctcg ctggtaagcc
     3361 tcgcgcagaa attattcgag agtatgagct tacgccttct tctttcgata aatggatgaa
     3421 gcaagcacaa tcaacgggct cattcaaa
//
LOCUS       DASHWW010000135         3419 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.139, whole genome shotgun sequence.
ACCESSION   DASHWW010000135 DASHWW010000000
VERSION     DASHWW010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.139"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            164..715
                     /locus_tag="U2R64_002854"
     CDS             164..715
                     /locus_tag="U2R64_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HEM8919598.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1391..1645
                     /locus_tag="U2R64_002855"
                     /pseudo
     CDS             1391..1645
                     /locus_tag="U2R64_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1715..2227
                     /locus_tag="U2R64_002856"
     CDS             1715..2227
                     /locus_tag="U2R64_002856"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8919599.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2224..3261
                     /locus_tag="U2R64_002857"
     CDS             2224..3261
                     /locus_tag="U2R64_002857"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEM8919600.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1253 a          577 c          678 g          911 t
ORIGIN      
        1 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
       61 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      121 accgaagagc gagcaagaca ggaacgagag aacaaacata ctcatgaaaa gactagaggc
      181 ttcgacctcg aactttaata ataagttaga tgtttttgaa gaaaagacta agcatgcaag
      241 attaaacttt gaaacaactg caaagcacta tattaaacga cttgatgaag ataatttgaa
      301 attagatttt caacaagcta ttcaagatga attaagcgat actaaagacg aaatacgtga
      361 agtgacgaaa caagcgagag aagaaacaaa agagtataaa gaaatcttag aaagtaaaat
      421 aaaagaccat aacaaagtgg ttgataaatc gaatacagcg ctaaaagtga tgacaaaagg
      481 cgttacaaat atattttttg tgctaattat ttttgtactt gtaatgcttg tgacaggtcc
      541 gataggtcat ttctttggta ttgaacattt atatagcttt attaatggtt ttattgatga
      601 ccacgaaagt gcatggcgat atttgatgtt gatactttat gcagtaccct atgtattctt
      661 cgctatcatt ctgtggctca tagcattgtt ttttagagta tttaatgacc tttaggtaga
      721 tttatatata aaaagggcta aatacgcaaa ataccccctt aaaatgcaaa ataaatgcaa
      781 ataagggggt aactccttat gaaaaaacaa ctaatagtat tataacacgt ttttatgccg
      841 agaaaactta ttggttggaa tgggctatgt gttagctaac ttgttagcga gttggttgga
      901 cttgaattgg gattaatccc aagaaagtac caactcaaca acacataaag ccctgtaggt
      961 tccgaccaat aaggaaattg gaataaagca acgaaaggag ttgagtaaaa tgagtgagaa
     1021 aacgaagaaa atcattcgag tatcattagc tttttcacaa gtagtagtgc aatcattgat
     1081 agtttattat acttaccagc aatataaatt atctaaagag aattaagttt tgattatgta
     1141 ataagttttg gtactaaaaa agacttgatc taattagacc aagtcttttg ttagtgttat
     1201 attaataaca aaataaaaat aagaagtcgc tcactccccg accaaagttt gtgagcaaaa
     1261 taaacagtcg atgtttgttt cttaattgta tatcttgata ttaaacgatt taagattatt
     1321 cttcaagata tatattcgca aatgtaattg gaaaagcgac ttcttaaaca aaattaagga
     1381 gtcgcttttt atggcaaaaa taacgaaaaa tgagcaagaa aatttggtgg aaaattacac
     1441 aaaaaaaccg gcgtactcta atagccggtt agacgcacat ttcgtgtgca cttctaatcc
     1501 gaaattgagc tttgacgcta tgacgatagt cggaaacctt aataaaaaca gcgctaaaaa
     1561 gctatccgat tttatgagtt tagatccaca aattagactt tgggatatac ttcaaacaaa
     1621 atttaaagct aaagcactac aagaccccct atgttaggct agttgtcgta taggataata
     1681 agttataata aagactatac ggaggatgat taccatgaca aataaaaaca atgaacgtta
     1741 ctctaccgaa ctgaaagcga cagccatcaa gaaaatgatg ccacccgaaa atagggggat
     1801 tcgccaatta agtcaaactt tgggcattcc agaagcgact ctttgttctt ggcgtaaaaa
     1861 agctagaatt caagggaata ctacacccgg aacgaaaaaa aatgtcgaaa aatggtcaag
     1921 tgaagataaa tttttaattg tgatggaatc attctcaatg aaccaagtag aacttgcgga
     1981 atattgccga aagaagggct tatttaaaga acaaattgag gcttggaaga aaacgtgctt
     2041 atctgcgaat gaacaggaag aaaatcgaac gagagaactt gcaactgaac taaaagaaga
     2101 gaaaaaacaa gcgcgtcaat tagagaaaga attacgtcat aaggaaaaag cattagcgga
     2161 agccgctgct ctcttattac taagaaaaaa agcacacgcg atttgggggg accaagagga
     2221 agaatgattt catcttcaga tcgcaaacaa gctgttgaac ttattcaaga agccaatcgc
     2281 aatggggccc gtctcaccta tgcctgtaat gagctgaata ttagcgttcg aacctacgaa
     2341 cgatggacgc gtgaaggtac gatagcgcat gatcaacgcc ctttggcgaa acgtcctgta
     2401 cccaaaaata aactgacgga tcaagaacgc gaaaaaataa tagaaaccgt ttcaaaaaaa
     2461 gaatttatga atttgccacc tagccaaatt gtaccaaaac ttgcggattg ctcgatttat
     2521 attgcatcag agtctagctt ctatcgtgta ttgcgagaaa aaaatatgca acatcaccgt
     2581 ggccgaagtc aagtttcaca aaaacgcata ccgccaagtc accttgcgac gaagccaaat
     2641 gaagtttgga cttgggatat tacttggcta aaaggtccaa taaaaggact cttttaccgg
     2701 ttatatctca tcattgattt atttagccgt aaaatggtag gctgggagat ttgggaatca
     2761 gaagaagctc gtcatgccga aaaacttatt aaacagacgg tgcttaagga acgtatccaa
     2821 ggacagccgt tggttttaca ctccgataat ggcagcccta tgaaagccgc gacttttcaa
     2881 gtcttactcg aaaaattagg aattcaaagt tcttattcaa gaccacgagt gagtaatgac
     2941 aatccttatt cggaagcggc tttccgaacg ttaaaatatc gaccagaata tcccaataac
     3001 ggctttaaaa caatagatga tgctcgaaaa tggacgaaag agtttgtcga ttggtataac
     3061 gattctcatt tgcatagtgg gattcaattt gtgtctcctg cagcgtgtca tgaaggacga
     3121 catctcgcta ttttagagaa acgaaagcag gtttacgagg acgctaaaaa gcgccatcct
     3181 gaacgctggt caaaaggtgt tcgaaattgg actccacatc aatcggtggc gttgaatcct
     3241 ttaaaagaaa cagaaagtta acaggagcat aatctttcaa gattatcaaa taaccctcgt
     3301 cacccaatag gggaaaaagt tattcttccc ctattggata acgaggccaa ccgaccatag
     3361 ggaggttctg ctttttgata ggtggaaaat aaaaatacga caactatatt gacaaacac
//
LOCUS       DASHWW010000136         3283 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.140, whole genome shotgun sequence.
ACCESSION   DASHWW010000136 DASHWW010000000
VERSION     DASHWW010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.140"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            2..586
                     /locus_tag="U2R64_002858"
     CDS             2..586
                     /locus_tag="U2R64_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8919601.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(663..1856)
                     /locus_tag="U2R64_002859"
     CDS             complement(663..1856)
                     /locus_tag="U2R64_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8919602.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1920..2300
                     /locus_tag="U2R64_002860"
     CDS             1920..2300
                     /locus_tag="U2R64_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEM8919603.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2374..2736
                     /locus_tag="U2R64_002861"
     CDS             2374..2736
                     /locus_tag="U2R64_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919604.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1114 a          539 c          622 g         1008 t
ORIGIN      
        1 tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg ttatcaaaac
       61 aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga cggttcaaaa
      121 tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc gcgttattcc
      181 tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg aaagtattta
      241 tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg gagctttatc
      301 tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa ataacacaaa
      361 tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag aaatcattga
      421 agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct ttggacatgt
      481 actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc cacaagaccg
      541 acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg gtatggtacg
      601 gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt tgaataaatg
      661 atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag taaagtttct
      721 tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa cgtgatgcca
      781 ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg gtcgtctgaa
      841 atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat tattctcact
      901 ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc tagataagga
      961 atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc aatcagtcca
     1021 aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc agctttcatc
     1081 tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa agtcttggtt
     1141 gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag catggaagta
     1201 aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag aatcacttga
     1261 tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac acgccctcca
     1321 ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat ttttttctcc
     1381 atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct tcgaacgatg
     1441 tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc atgaatcaaa
     1501 atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt taacacacca
     1561 cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg ttcccaatga
     1621 atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc atgtttgatg
     1681 tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc tgctacccac
     1741 aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt tacactttct
     1801 gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc agtcattttc
     1861 gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga gggaagtaga
     1921 tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag ccttatggcg
     1981 cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa gtacaatccg
     2041 gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca gttcagatca
     2101 tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta gaaaaaacaa
     2161 atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt aagatcggat
     2221 ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct gaactagaac
     2281 ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga atttttatgt
     2341 aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt tgctggtaca
     2401 attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat tgatgacaag
     2461 ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa tatacttaat
     2521 ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga attgacaaat
     2581 acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca aaagaatcaa
     2641 agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg ctctgttctt
     2701 ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc gaacaaagaa
     2761 gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac aatgaaatgt
     2821 tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa acggttgtat
     2881 aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa tttatagttg
     2941 accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga tgttatatca
     3001 catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg ataagataac
     3061 tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa cttcaaaaaa
     3121 gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag atttcgaaaa
     3181 acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc tgatatgata
     3241 taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tcc
//
LOCUS       DASHWW010000137         3280 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.141, whole genome shotgun sequence.
ACCESSION   DASHWW010000137 DASHWW010000000
VERSION     DASHWW010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.141"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(366..1484)
                     /locus_tag="U2R64_002862"
     CDS             complement(366..1484)
                     /locus_tag="U2R64_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919605.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1955..3262
                     /locus_tag="U2R64_002863"
     CDS             1955..3262
                     /locus_tag="U2R64_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEM8919606.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1032 a          680 c          590 g          978 t
ORIGIN      
        1 tttaaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttca caaaaatttg
       61 agaaataatt tttgtcaatc tcttcttatt tcttgaagct gaccacttct gtcacaacct
      121 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccacca aacaaaaaat
      181 atgaagagct atttttgctt gctgttctta ttacttgatg cagaacagct ttttcacaac
      241 ctctcataca cggtgtttaa tcagctgacc ttcggtatta gctcaaaaaa cggaaaaata
      301 tgtgaaacta tttttccgtt tgtttctcta atactcaggt caaaacactg atttcacaac
      361 ctcttttaat aacgaagaat cgctgtcaga ctcttttcat ctggcgcatc tttttgatcc
      421 aaaataaaca ctttcccgcc attaatgatc acatcatctg ctaatgcatt caacacttga
      481 cgccgatcat attctgtttc aggatcttca ccgaaaccat cagctaagtt tgacgtagcg
      541 ataaataaat gtgacacttt tccttctttc gcagctggaa cgatatcaac taactgatcg
      601 atgaatttct tatctaagag tttattgtat tcttttgatt cttgagctgc gagttcactt
      661 gacagcttct tcgccccttc ttcgatatct ctaaaggata gctgcgcagg agaagcagaa
      721 atcgcaacgt ctgcacaata atagggattt ttagcaattt ttttgaacat cgtctgattt
      781 tctggtaatg caaataaata aatcggccat tgttcaggat tttcgaaaga atccttcaag
      841 tacgtatcaa cagcttggta atagttgacc caatcgatct ctacttcttc atcttttgga
      901 tttacgccat ggaaagttac tccatctcgg gctccgcctc ctccattaga agagaagttc
      961 aaaccgccac ctgtcagttc agatcccaat gcagtaacga catcaaccgg tgccccttct
     1021 ggtagagata cttcttttac ttgtttgttg ctgacctcat acaatttcat ggagtcgcgg
     1081 ttcaatccca ataaataata agaatagttg aactgcccat ttttgataat agccagtaaa
     1141 taaggaagat cacttacata gtattgatcg tctaccggga tactcaaacg atggatatag
     1201 gtctggtcag cagttataat gaccgctaca ctcgtagttg cactacgcca aaacgaagga
     1261 tctcctaaca aattttcaat tttttcttgg aacggggacc agtcatgttc ggaatatttt
     1321 ttctcaaaac gtttctttgc ttctttcgca aaatttttga atttgatctg atctttttcc
     1381 acatcttgat gggcgacatg cgtattcagc atgatcgtga cgaatggtcc tttagcgcct
     1441 tctgaagtca attgtgtcaa taattcttta tccttttttg ccataaacgt acccctccta
     1501 aaaaaatcat tcctttgttt ctatctaaag tctaccacaa cactattttt ccatacaata
     1561 aaacgtatct aaaaaaataa aacggtttct acggttttaa atttagctat ttttttaagt
     1621 tatcttcata atttcctcaa ttatttagcc ccagtcttca actattcttc atgaaatgct
     1681 gataaactaa gaaaaagaat aaaagaggtg gatcttatgc atttgattat gattttcagt
     1741 ttattaagta ttatcagttt atttgctttc agcgcttccc gcttattaga tgcggaaaca
     1801 cagcctattc ctgtaaaagt acgtaaaaac gaccgctaaa cttccataac gcgcgttctt
     1861 atcctaaagt tttttcagaa acattgaaac tctctcccct ctctgataaa attttaattt
     1921 gtagcgaaac aaattaatta caaggagatc ggatatgtcc ataaaaaaaa cacgtctagt
     1981 cctattattg gctagtctca ttctttgcct tgcttctttt ctaccagctg ttgctgtgca
     2041 agctgaagat acgttcaaag taaatgcaaa agcagctttt gctgtagatg cgcaaagcgg
     2101 taagattctt tatgatcaag atggagaaaa aaccatgggg atcgcttcaa tcacaaaaat
     2161 catcggtctt tacatcgtcc ttgatcaagt aaaagaagga aaactgtcat ggggtgataa
     2221 agtttcgatt tcagattatg cagaaaattt gagtatcacc ccagatttat cgaatgttcc
     2281 tttgcataaa gaaaacacct acactgtcaa agaattattc gactctgcaa tcatccagtc
     2341 agccaatgct tcaatggtgg ccttggcaga aaaaatctct ggcagcgaag ctaaattcac
     2401 tgaacgaatg aaagaacaat tgaaagattg gggaatcaaa gatgcaacaa tcgttaatgc
     2461 atcaggattg aacaactctt atcttggcga aaaccgacca gaaggcactg gagaaaacga
     2521 cgaaaatcaa atgtctgctc aagatgtggc catcgttgcc cgccatttga tcttggattt
     2581 cccagaaata ctggatgtat caagtactac gacccaaatg tttggcgaaa atacgcaatc
     2641 accagtggaa atggtcaact ggaactggat gctcccagga ttcgttaatt acaaggaagg
     2701 cgtggacgga ttaaaaactg gtacgactga gcttgcaggt gcttgtttcg ttggtacgat
     2761 cactaaaaac gatcaacgga tcatcactgt cgtattgaat gcggacggcc atgcggaaaa
     2821 cccgagtgcc cgcttcaatg aaacagaccg tttgatggac tactgctatg acaattggtc
     2881 agaaaaagag ctcggaaaag ctaacgcaag tattcctagt ctaaaaacca ttgatgtaaa
     2941 agacggaaaa gaatcaacag ttcctgttgt gcttaaaagc cctgtaaaag tatgggtacg
     3001 aaacgatatg gatactggca aattaacgat cacgccaaca cttgacaaga agcaagtcac
     3061 tgacaatgag atccaagcac ctatggataa aggtacaaaa atcggtaccg ctacgatcac
     3121 cttggcagac gataaattag gctatttaga agacaacaat gcaccatcaa cagagatcat
     3181 tacggataaa acagtggaaa aagcgaatat attcgtgatt ggctggcgac gcgtcgcaga
     3241 atttttcggc aacttgtttt aattgaacaa taagaaaaac
//
LOCUS       DASHWW010000138         3221 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.142, whole genome shotgun sequence.
ACCESSION   DASHWW010000138 DASHWW010000000
VERSION     DASHWW010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.142"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            50..1438
                     /locus_tag="U2R64_002864"
     CDS             50..1438
                     /locus_tag="U2R64_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HEM8919607.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3221
                     /locus_tag="U2R64_002865"
     CDS             1776..>3221
                     /locus_tag="U2R64_002865"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEM8919608.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEEE"
BASE COUNT         1185 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaaga a
//
LOCUS       DASHWW010000139         3179 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.143, whole genome shotgun sequence.
ACCESSION   DASHWW010000139 DASHWW010000000
VERSION     DASHWW010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.143"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(7..978)
                     /locus_tag="U2R64_002866"
     CDS             complement(7..978)
                     /locus_tag="U2R64_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEM8919609.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            1684..3063
                     /gene="brnQ"
                     /locus_tag="U2R64_002867"
     CDS             1684..3063
                     /gene="brnQ"
                     /locus_tag="U2R64_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEM8919610.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMPLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
BASE COUNT          894 a          633 c          593 g         1059 t
ORIGIN      
        1 caaagcttat tcttgatgga gatctgcctt ttcataagct ttgatgattt cggcaactac
       61 agggtgccga acaacgtcac ttgcttcaaa attaacaaaa tcgattttct tgatttgctt
      121 taatgttcgt tctgcatgaa caagaccact tgttgtccct cgaggcagat caatctgact
      181 cgtatctcca ttgacaatca tttttgattg ataaccaaga cgtgtcagga acattttcat
      241 ctgagcaact gtcgtgttct gtgcttcatc caaaataacg aatgcatcat ccaatgtccg
      301 cccccgcatg taagctaaag gagcaatttc gatcacgcct cgttccatca atcggttcgt
      361 atgatctaat ccaaaaattt ggtataaagc atcataaaca ggacgcagat aaggatctac
      421 tttttctttt agatccccgg gaagaaagcc tagattttcc cctgcttcca cagcaggccg
      481 cgtcaaaatg attttttgca cttcaccttt tttcaaggca gcgattgcta atactactgc
      541 aagaaaagtt tttcctgtcc cggctggtcc tacgccaaat acgatatcat gtttggctac
      601 cgattcgaca tatttctttt ggccgctgtt ttttacccgt attggttttc cattacggtc
      661 tttgacgatc tcttcctcat acatttcaac aaaataatct aatgtgcctt tttgccccat
      721 tttcagtgcc gtcacgacat ctggtgtact tacatggatt cctcgtttga tcaattcctg
      781 caatgtccga atgactgagg cagccaagga aatctgggat tgttcgccaa tgatctgaat
      841 gatttctcca cgtgtatgga tggttgtttc tgttgtttct tcaatcagtt ttatatgctt
      901 gtcgtgtgca cctaaaagca tgctgacatc atcagcagcc gtcaatctaa tctctaaaga
      961 actagactct tccgtcaaaa atagacatcc cctttttttc gattcattct ttcctatttt
     1021 accatactca gaagaaacta tatagcaaat aagaaaaggt tctaaaagag ttgcttaacc
     1081 ataagtacca agaaacgtta aaaaatagct gcttccattc tctaaaggtc tcgtttgaat
     1141 aaaaaaagct gatcatgtaa gctatgcata agatagagga caagtattcc gtctaactta
     1201 gcaagtattc tctgggtatt tttcttgttt caaaaaaaga aaacaaaata tttgaaatat
     1261 tcttgcattt caaaaaaaac aggtgtatta taacgtcaac aaataaatat acagcaaagc
     1321 gtcgaggaaa acagtaggct attcagcgat ttattcccag tgagtcatgt aagtgagaaa
     1381 tgacaataaa tcgaatagac gaacatcatt tccgagtcaa tgtcgaaaac gtagatcatt
     1441 gtggctgcct ccattatcag gctagcggat aactttatcg aaaagcgtcc gtgaatgaag
     1501 aagctttttt aagcgaaaaa aggtggtacc gttctagaat ctagagccct tttcccaagt
     1561 ggaaaagggc ttttttttat attttaaggt ggtggttttc atggaatctg atattagtgg
     1621 catttctagt ttctgcaacg tttattttgt tactcaaaat gataattatt ggaggaaaaa
     1681 tttatggaag aaacaaaaac ttattcatgg aagcaattat tgatggtcag ttcacttatc
     1741 ttcgggatgt tcttcgggtc aggtaatctg atctttcctg tccacttagg tcaaatggct
     1801 ggatcaaact ggatcagcgc tggtgtagga tttgccatct caggcgctct tttcccatta
     1861 ttagctatct tagctgtagt agtgacaaaa agtgatggtc tgtatgactt agctaaacct
     1921 gtcggaaaat ggtatgctgc cttgttcttg atccttgttc atttaacgat cggaccattc
     1981 tttggtacac cgcggacagc agcaactgct tttgaaatgg ctgctaaacc ctttttgcct
     2041 gaaaaatatg attcattagg tatgttttta ttctctgctc ttttcttttt acttgcttat
     2101 ttccttactg tacatccaac acgtttggtc aaatatgtcg gaaagtattt aaactccttg
     2161 tttcttgcat tattagctat catttttgtc gtttctttat tccaacccat ggggaatcta
     2221 aaccaatctg ctgcagattc ttatcagacg aacgctttga caaatggcgt tttagaagga
     2281 tacaacacgg ttgatgcagt agctttactt gctttaagtg tcacttttgt ccatgcagtt
     2341 cgtgatcttg gttttaaaga taaaaaagtc acagaattaa cagcaaaagc tggtagcctg
     2401 agcgttgcgt tagaagtcat gatttatttt ggtctggtcc ttctcggtgc gatgagtttg
     2461 aataagatgc ctttatcaga aaatggcgga actgcacttt ctcagatcac taatttttat
     2521 ttaggtaact tcggtgctag cttcttaggg gtaatggtca cattaggtgt cttcactacc
     2581 gctatgggac tcgttgtttc ttttgcacaa gatttccata aactgttccc taaagtcagt
     2641 tatatgacat ggctgcggtt aacgactttt gtctcttttg tcgttgcgaa tgccggattg
     2701 gataatatca tccaatggtc tttaccagta ttgatgcttt tgtatccatt gtcacttgcg
     2761 ttaatcttgc tttccttaac agcaaaattc ttccaaaaga gtccatttgt ctatcaagta
     2821 acgatgttct tttctgccgt tccagccgta ttggatatgt tggcaaattc gcctgcatta
     2881 gtgagtcagc aaactgtcgt agcaagctta ctaggatttt atcatcatca cgttcctttt
     2941 gctgcattag gacttggctg gatggtccca acgttacttg gttacgctgg cagcttactc
     3001 ttttattacg cctatcgcct atcagggtat aaacaagaag caaatgaact accagaagaa
     3061 taaccaaatc aaacacaatt taacataaga gatattaaac aggaaaaaaa cagctagaag
     3121 aaagaataag attctttctt ctagctgttt tttagttctt tttttatgaa cacaaaaaa
//
LOCUS       DASHWW010000140         3090 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.144, whole genome shotgun sequence.
ACCESSION   DASHWW010000140 DASHWW010000000
VERSION     DASHWW010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3090
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.144"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..418
                     /locus_tag="U2R64_002868"
                     /pseudo
     CDS             1..418
                     /locus_tag="U2R64_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            434..583
                     /locus_tag="U2R64_002869"
     CDS             434..583
                     /locus_tag="U2R64_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919611.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            664..1260
                     /locus_tag="U2R64_002870"
     CDS             664..1260
                     /locus_tag="U2R64_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEM8919612.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1273..2172
                     /locus_tag="U2R64_002871"
     CDS             1273..2172
                     /locus_tag="U2R64_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEM8919613.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEDIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            2175..2306
                     /gene="ssb"
                     /locus_tag="U2R64_002872"
     CDS             2175..2306
                     /gene="ssb"
                     /locus_tag="U2R64_002872"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8919614.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            2328..2660
                     /gene="ssb"
                     /locus_tag="U2R64_002873"
     CDS             2328..2660
                     /gene="ssb"
                     /locus_tag="U2R64_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8919615.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            2705..2938
                     /locus_tag="U2R64_002874"
     CDS             2705..2938
                     /locus_tag="U2R64_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919616.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
BASE COUNT         1117 a          528 c          646 g          799 t
ORIGIN      
        1 cttacgagcg ccgaaatgac cgccaaatgg gaaagctact tgttaaagat cggtgaacga
       61 aaaggaacac aaaccacttt tctagccaat atccaaaaat ttgtctctca cttattggaa
      121 gtcgtaccag ggcaaatcca atccactgat tttggatcga cgttacaaga agtgaaagca
      181 gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt gtccaaaatg ccaggaacaa
      241 gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg aagcctgtga ttttaaaagg
      301 tcagaagggt tcatttgaag caacgattgt tttaaaagaa gacttcacta caggctttga
      361 attttctgaa aagaaaaaaa cgaacttcaa gaaaagaaca cgccgcactg caaaataatg
      421 gagggttaat cttatgcgta ataccacaca caaacaacaa gaaatcgaaa atcaaaaagc
      481 caaaattcgt tcagaacagg aaaaaatgcg tgccagcaaa cgaagactgc agcaattgaa
      541 gaaccagcag aggattcaaa aagaaatcga attagatcga taaaatcttc ctaactattg
      601 tatacgtata aacttatgtt atactgtttt tataagttta tacgtataca aaggagggag
      661 aaaatgacaa aagcaatggt atacaagctg ctagaagaat ttaatggaac tttggctttg
      721 aaggatgcca aaaaagcggg catttctcct gtaacgatca aacgtatggt agatcgaggg
      781 gagctggatc gagagtatcc aggttttttc accttacctg gtcaatttcc tgatgaattg
      841 tttatggcgc aaaaaaaata tgaacgcggc attatttcac atattaccgc gttagatttg
      901 tatgatttaa cagatatgat ccctagacag atcgatctga ctgtacctta cggttatcac
      961 gtttctgaaa aaggattgaa ggaattcgca gttgagctac actatacaaa agcggaatgg
     1021 tatgaattag gtaagattga aataaaaagt cgctatggga atcctattat agcttatgat
     1081 ccagaaagaa ctttatgtga catttggaat ccctggtata ccgttgagga tgaaatcaaa
     1141 gtaaaagcaa tcaaaaacta tatggagtcg gacagaaaaa atcttagaaa attgaatgag
     1201 tatcgacgaa ttttaccaac agacaaaacg atgcgttctt atattatggc tttaaattaa
     1261 aggagaagat acatgacacc tacgcagtta aaagcaaaag tgaagaatat ttctagagaa
     1321 aaagaagttg atccgcagct tgttttaaga cattttatga tggaaaaatt cttggaaaaa
     1381 atctcagagt ctccttatcg tgaaaatttt gtgttaaaag gcggcttctt gattggctca
     1441 aagtatggca ttgaaaatcg cacaaccaaa gatattgata cgactttacg ggaaatgaaa
     1501 gtaaccaaag aaacattaac aacggttcta aacgaaattt tttcaacgcc gacgaaagaa
     1561 gacattcaat ttgagattca aggaatgaaa gaaacgagag aagccgatta ctatccagga
     1621 tttagcttac gtgtgctggc acatttggaa aacatgcggc cagattttaa ggtagatgtg
     1681 actacaggtg actcgatcta tcctgcaacg atcactcaca gtcataaatt gatgtttgag
     1741 gatcgaacga ttcctttgga atcctatcct acagaacaaa ttattgctga aaaattaagt
     1801 gcaacctttg attttttaac agataattcg agaggaaaag atttttatga tctctatact
     1861 attcctaaaa tggagaagat cgatgagaag accttgaaag atagtgtgag aaatacattt
     1921 acacgtcgag gaaaaactga tccgttaaag atatactatg aaaaggatat ggatgtactg
     1981 aaaaatagtc acgagctaaa agatacctgg aagaaatatc aaaaaagcaa tccttatgct
     2041 gcgtcgatca cgtacgatga gacaatggat tcgattagta atttgatgga aaaagtgatt
     2101 cacgtcgaag aaaaagagcg aaaactagct tatcaaagac accaacagat gaatagagaa
     2161 atggagagat aaagatgatt aataatgtga cattagtagg acgcttaacc aaagatcctg
     2221 atttacgtta taccgcaagt ggtactgcag tagcgacttt taccctagcc gtcaaccgaa
     2281 atttcacgaa tcaaaacggc aattgagaag ccgattttat taactgcgtg atttggcgca
     2341 aaccagcaga aacaatggcg acattagcta aaaaaggtag cttgattggt gtagttgggc
     2401 ggattcaaac gcggacttac gacaaccagc aaggacaacg tgtatatgtg actgaagttg
     2461 tagcagataa ctttcaacta ttagaaagta aagcagcgac agagagccgt gcgcacgctg
     2521 atcaatcgtc caccagtcca agcaccgcca cctttgaaca acggaataca gcgacgccta
     2581 acaacaatgg attgaacgct tcacagaatc catttggtgg acaatcaatc gatattagcg
     2641 atgatgatct accgttttag tttgagaaag aaggagtaag catggcaaaa aaattagtct
     2701 gacgatggat ctattgatac ccgtaattgc atttatagac gggatttctt tgggcgtcac
     2761 tgaaaatcct ttggtaaata gaattgcgaa aggatcacta tttcttgtat tcgtgtatct
     2821 tgtctgttct tatcttttaa aaagagcagg aaaggataat tccttttggc gattgactaa
     2881 agtcacagta gcagcgacag ctgttatact tacggctatt ctaccgcttt atatgtagag
     2941 ttaacgggaa atcgttgaac ttcttgcgaa atattgctat aatgaacatg aaaaagagga
     3001 gttgcgctaa caacccctca ttaacagcac cgattaaaga acggtggcag aatattagtt
     3061 atttggaaat aaccgctgac ctgctaaagt
//
LOCUS       DASHWW010000141         2952 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.145, whole genome shotgun sequence.
ACCESSION   DASHWW010000141 DASHWW010000000
VERSION     DASHWW010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.145"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            89..406
                     /locus_tag="U2R64_002875"
     CDS             89..406
                     /locus_tag="U2R64_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEM8919617.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="U2R64_002876"
     CDS             complement(497..862)
                     /locus_tag="U2R64_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919618.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1069..1551
                     /locus_tag="U2R64_002877"
     CDS             1069..1551
                     /locus_tag="U2R64_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919619.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1748..2638
                     /locus_tag="U2R64_002878"
     CDS             1748..2638
                     /locus_tag="U2R64_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEM8919620.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1007 a          460 c          567 g          918 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaagttttt ccccctaatt tttttagata
     1021 gaaaattgta tagtatgatg agagaaaaag tagtttgggg gaacgttaat gagaagaaaa
     1081 gcagtaatcg atcggcttta tttatttttt tggttttttc ctatcgtttt gctacctttt
     1141 acatgggtaa atgctgttgt acaaggtgcg gagatattag gcctgatcca aggaagcgga
     1201 tttgtggttt ctaggaattt tccagctttg attgttttct atttagtgat aagtgtaggt
     1261 ctcttattac caaaatctct gatcaatcac tacaattggc agctgcttta cttttcttgc
     1321 ttattagtat ttacatctac gttttctttg ctgcctcgct tgattatcgg ccctaatggt
     1381 ttgagcgaga gtggattgaa ggatttagct tattcctcca tgtatttctt gacgatcaaa
     1441 ccatggttct atttagtaat tgcctcattt attcttgcaa cattttttta cttctggaca
     1501 gaaatcagga taaaaagtga acgatctgta tctataaaaa ataactattg atggtggatc
     1561 atcagtaaaa aaacatatga gctgcgtaaa atgcatgttt ctcatatgct ttttttatta
     1621 ttatgtaaag aatgcgaaaa acgtttacat gatttttaca taacttaact atatttttac
     1681 agcaaccata cgagggattt acagtcgact gataaacttt agttgtaaat aagaaaggag
     1741 caataaaatg aaaaaagtat tgtttactct aggtatgatg ggaattcttt tagccggatg
     1801 cggctcagga tcaggaaata cagatggctc tgccacacaa aataattcaa gtgactcaaa
     1861 tgaacaagta aaaatcgttg cggtaggttc gacagcatta cagccgttag tcgatgcagc
     1921 acaagaaagc tttgtacaag aaaatccaaa ttatcaaatc tctgtacaag gaggaggaag
     1981 cggaactggt ttgagccaag tcgaagctgg agcagttact atcggaaact ctgatgtatt
     2041 tgcagaagaa agagacggag ttgatgcttc aaaattagtg gatcataaag tagcagtggt
     2101 cgggatggca ccaatcgtca ataaagatac agatgtcaaa gatatcacca aacaggaatt
     2161 gattgatatc tttacaggaa aaatcactaa ctggaaggaa gttggcggga aagatcaaaa
     2221 aatcaacgtc gtgaaccgtg caaacggcag cggtacccgc gcgacattcg aaaaatgggg
     2281 actggatggt gctacccctg tgcagtccca agaacaagat tcatcaggaa cagttcggca
     2341 gctggtaagt caaacaccag gagcaatcag ctatttagct ttctcatatc tcgatgattc
     2401 cacacaagca ctaagtatcg acggtgtaga accaaaagaa gagaatgtag cagataacag
     2461 ctggggaatc tggtcatatg aacatatgta cacgaacgga aaaccttccc ctgaagtcca
     2521 aaaattctta gactacatga tgacagaaga aatccaagaa ggacctgtca aagaattggg
     2581 ctatttacca atcacaatga tggaagtaga acgtgatcac gaaggaaata tcaaataact
     2641 agcagataaa catgccacgg tagtcgttac tattaaggaa aagcaactat gtttccccac
     2701 atatacattt ttcctttaat tgtgaaaaat agttcctcat attttgccgt tttttgagct
     2761 aataccgagg gtcagctgat tgaacaccgt ttattcgaaa aaaagagcta cgacatagaa
     2821 ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg tgaagacaaa tttgaataaa
     2881 acttagaccg atatgcggcg cgttctgtgc gccgcatatt tttttagttt tcaaagatca
     2941 gaccttgttg ta
//
LOCUS       DASHWW010000142         2930 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.146, whole genome shotgun sequence.
ACCESSION   DASHWW010000142 DASHWW010000000
VERSION     DASHWW010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.146"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            4..963
                     /locus_tag="U2R64_002879"
     CDS             4..963
                     /locus_tag="U2R64_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HEM8919621.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1152..1225
                     /locus_tag="U2R64_002880"
     tRNA            1152..1225
                     /locus_tag="U2R64_002880"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1186..1188,aa:Ile,seq:cat)
     gene            complement(1740..2039)
                     /locus_tag="U2R64_002881"
     CDS             complement(1740..2039)
                     /locus_tag="U2R64_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919622.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2045..2275)
                     /locus_tag="U2R64_002882"
     CDS             complement(2045..2275)
                     /locus_tag="U2R64_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919623.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(2525..2725)
                     /locus_tag="U2R64_002883"
     CDS             complement(2525..2725)
                     /locus_tag="U2R64_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8919624.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          998 a          499 c          503 g          930 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagatcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt cactatcacc cataatagtc acactccaag
     1081 ctatgcgata acaggtttgt tgccacacat tctactggtt gattgtttat ggctttatgt
     1141 ggcaacaacc agtaccctta gctcagttgg tcagagcaga cggctcataa ccgtccggtc
     1201 gtaggttcga gtcctacagg gtacattaac gtagccattt gaatcgttct gtgttagaat
     1261 tttttgaaga gtattataca agctaaagct tttcttcatt gccactcaaa tgagtggctt
     1321 ttttatgtat ccttttatgg attaatgaaa ggatgtttca catagttata tttctgtata
     1381 tttgaaaagt tttactttga tttttaaata gaaagacatt tgggttatat tgtgagataa
     1441 taataaagaa gagtttaaag cgttccccaa aaaccactgc cccataagtg tgttacgctt
     1501 taaactcttt tatatttgaa gccattaaaa agcataccat atttttgaaa aaaagtgaga
     1561 aaaaaggctt ataattggag tggtagttaa ttagtgactt atttttgatt ttatagcact
     1621 gatactataa aatatagata tcatcatatt acacaatctt aatactaact taaaaaatat
     1681 ctcctttcat aagtatggtg ataaaatccg ttccgggcta cctttttagg tagcctactt
     1741 taatctttgt atctttctgg atcaacgaaa gtatacttta tatagtcata acgccgatga
     1801 tcgcttcgag cgtctagcac atcagtcacg atatcaaaca aaaaatatac gtctttcttc
     1861 attctagttt tcgcagcagg gattttaaag tagttcttat tagaatagta gagattaatt
     1921 aataagctat cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct
     1981 ttgacaaatc tattcgaagg atcaaattta aaccataatt gcgtctcatt aaaaagcata
     2041 accattactc cgatctattt ttaaacttag tctctacctc taatatatat cgagttttta
     2101 ttttgccttc agagaatact gtttcttttt ttgcagttac aggttgttta ttttcggaaa
     2161 aagctaatat agctaaaatt gaaacatcca tctggaattt gtctttttcg ttgctttgct
     2221 cataaaaatc tgcatattca tcactaatat tttttctaat aaattcttcc atcataaaga
     2281 tcacctcgaa aagagtatac gaacaaacgt tctttttgta aaggtggaat ttattatact
     2341 aaataaatag gtgaacaagt acttgtgcca aattatgtgc caaaaaaaat cgaatttaat
     2401 aaaacacaaa caaaaagaaa tcctattatg ataacatttc ttataataac aaacacaaca
     2461 gaagacgtgt aatagttagt caggaacgta caaataaccc ctgtatcctt tgcggtacag
     2521 ggggttattt tgtataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg
     2581 atacgctaag tatatttact ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc
     2641 catcaataaa cagtcgaaga gaaaataggg aaaaattgat tactaaagaa aaacttacta
     2701 ggtcgacggt gtagttgatt ttcatacttc aatagattcg aattaaacga tttcgattgg
     2761 cttataccag tcctatccaa cgaaagatat atcgttctta actctagcgg tataacttga
     2821 agctttacgt aaagccaatg ggaatgaact ggagatgact ttttattatt tttagtaata
     2881 gctgatgggt taatacttac aactttcctt ttcaaagtac catataaaaa
//
LOCUS       DASHWW010000143         2731 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.147, whole genome shotgun sequence.
ACCESSION   DASHWW010000143 DASHWW010000000
VERSION     DASHWW010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.147"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            179..775
                     /locus_tag="U2R64_002884"
     CDS             179..775
                     /locus_tag="U2R64_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEM8919625.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="U2R64_002885"
     CDS             899..2698
                     /locus_tag="U2R64_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEM8919626.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT          776 a          468 c          516 g          971 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctataatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac a
//
LOCUS       DASHWW010000144         2631 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.148, whole genome shotgun sequence.
ACCESSION   DASHWW010000144 DASHWW010000000
VERSION     DASHWW010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.148"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            2..1147
                     /locus_tag="U2R64_002886"
     CDS             2..1147
                     /locus_tag="U2R64_002886"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEM8919627.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1318..1776
                     /locus_tag="U2R64_002887"
     CDS             1318..1776
                     /locus_tag="U2R64_002887"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEM8919628.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1935..2405
                     /locus_tag="U2R64_002888"
     CDS             1935..2405
                     /locus_tag="U2R64_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEM8919629.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2458..2573)
                     /gene="rrf"
                     /locus_tag="U2R64_002889"
     rRNA            complement(2458..2573)
                     /gene="rrf"
                     /locus_tag="U2R64_002889"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          860 a          504 c          496 g          771 t
ORIGIN      
        1 catgcacatt caaacaaaat tgatccacgg aggcatcagt gaagatccca caacaggagc
       61 tgtcagtgta cctatttatc aaacatccac ttatcggcaa gatggcgtcg gccagcctaa
      121 acaatatgaa tattcaagat ctggtaatcc tactcgtttt gcattggaag aactgattgc
      181 tgatttggaa ggcggtgttc gaggattcgc tttttcttct ggtctttctg ggattcatgc
      241 cgttttttct ctttttcaag ctggcgatca tatcttatta ggagatgatg tctatggagg
      301 aacattccgt ctatttgaca aagttcttac taaaaatggt ctcgagtaca cgatcataga
      361 tacgagtaat cttgataaaa tagaacaatc catcaaaccc aatacaaaag cactttatct
      421 tgaaacacct agcaatccgc ttctaaagat tactgattta gaaaaaagtg ccactctggc
      481 tcatcaacat ggattgatag ttattgctga caatacattt gctactcctt attttcaaag
      541 acctttagat ctcggttctg atatcgttgt ccatagcggt accaaatatc taggcggaca
      601 cagcgatgta gtagctggtt tagtgacttc taaccataaa gatctagccg atcagatcgg
      661 attttaccaa aatgctatcg gagccgtact tggtccccaa gatagctggt tacttcagcg
      721 cggaatcaag acactaagtg ttcgtatgga ggaacatcaa aaaaatgctt ttgtggtagc
      781 tgattttcta ttttctcatc cagcagtaga aaaggtctac tatccaggat tacccgatca
      841 tgaactccat ggagttgcta agcagcagat gagcggcttt agcggaatga tttcttttac
      901 tttaaaaaat gaagaatctg ctattccatt tgttgaatca ctccaactat ttactttagc
      961 agaaagttta ggtggcgtag aaagtttagt ggaaattcct tctgtcatga ctcatgcgtc
     1021 tattccaaaa gaaaaacgag aagaggctgg cataaaggac ggcttgatcc gtctttctgt
     1081 aggaattgag tatggtcagg atctcataaa cgatttagct caggcatttg acagaatcaa
     1141 gaactagaag tcccaataaa cgacttagca gaaaaatcta aaaaatattt cagattgcta
     1201 caccttggaa acgataagtg ttagaatcaa gtagaaagac gtttttgtaa atttcactaa
     1261 ataattcttt agtgaaaagc atcaaaacga atgaacaaac agataggagt cttacaaatg
     1321 agaatgaatg tcgaaagttt taatcttgac catacaaaag tcaaagcacc ttatgtacgt
     1381 gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca ttaaatacga cgtccgcttt
     1441 aaacaaccaa ataaagaaca catggacatg ccaagtctac attcacttga gcacttgact
     1501 gccgaactaa tccgcaatca cgcagattac atcgtagact ggtctccaat gggatgccaa
     1561 acaggctttt acttgactgt attgaatcat gaaagctacg aagacatttt agatgttctt
     1621 gaagcaacaa tgaaagatgt tcttgaagct actgaagtac ctgcaagcaa tgaaacacaa
     1681 tgtggctggg ctgccagcca tacactagaa ggtgcacaag ctttggctcg tgaattttta
     1741 gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc taaaagaacg taaagatgag
     1801 aagcaatata gctatcttat cttcgtattt tattaaatat ttattgtctg aaaagagttc
     1861 taaacgggaa aacaaatagc tagttttcag tttagcgctc tttttattat ataaaataga
     1921 aaggagaaaa ctttatgtct atttataatt ttgaaactac tttagaagac ggcactgtct
     1981 attcattgaa aaaatatgca ggcaaaccga taatcattgt taacactgca acaaaatgcg
     2041 gtctagcacc tcaatttaaa caattagaag aactttacca agcttatcag acacaaggtc
     2101 tggttatctt aggctttcct tccaatcaat ttaaacaaga gctagattca gcgactgaag
     2161 cagcagaagc ttgtaaaacc acttatggcg ttaccttccc tatgcatcaa ttgattgacg
     2221 taaatggaga aaatacagat cctcttttta cttatcttaa aaatgaagct cctggtactg
     2281 tcactaaagc aataaaatgg aattttacta aatttttgat tgatagaaat ggcaaagtaa
     2341 tcgaacgatt tgcaccacaa acttctccat tgaaaatgac cgctgcaatt gaatccgttc
     2401 tttaacttaa taaaaataaa aaaagatgaa ctatttctag ttcatctttt tgcctttgcg
     2461 tggcgacgtc ctactctcac aaggggcaac ccctcactac aatcggcgct aagaagctta
     2521 acttctgtgt tcggcatggt tacaggtgta tccttctcgc tatcgccacc acactgtggt
     2581 gttatctttt attgagtaaa ttttgttcac tcaaaactgg atttgaagtc a
//
LOCUS       DASHWW010000145         2398 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.149, whole genome shotgun sequence.
ACCESSION   DASHWW010000145 DASHWW010000000
VERSION     DASHWW010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.149"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            207..2069
                     /locus_tag="U2R64_002890"
     CDS             207..2069
                     /locus_tag="U2R64_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8919630.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="U2R64_002891"
     CDS             2069..>2398
                     /locus_tag="U2R64_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8919631.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DASHWW010000146         2219 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.151, whole genome shotgun sequence.
ACCESSION   DASHWW010000146 DASHWW010000000
VERSION     DASHWW010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.151"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..375
                     /locus_tag="U2R64_002892"
     CDS             <1..375
                     /locus_tag="U2R64_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HEM8919632.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            423..1823
                     /gene="yfcC"
                     /locus_tag="U2R64_002893"
     CDS             423..1823
                     /gene="yfcC"
                     /locus_tag="U2R64_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HEM8919633.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1856..2023
                     /locus_tag="U2R64_002894"
     CDS             1856..2023
                     /locus_tag="U2R64_002894"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919634.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            2077..>2219
                     /locus_tag="U2R64_002895"
     CDS             2077..>2219
                     /locus_tag="U2R64_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8919635.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTI"
BASE COUNT          625 a          370 c          478 g          746 t
ORIGIN      
        1 aatgtttcca cagaggactt ctttaattat tgtcgattag aggaaagtgg tgtaacagtc
       61 actagcggta cagatttacc gctgtttatt actgatattc ctgaatcgat tataagagca
      121 gtattccgtc gttttcctga aggagaagaa gtctgggaga aagaaacaag cttcacgaca
      181 accgagctgc tgaaaagttt tacaagcaac agcttcaaag taaatggttt atcggagtac
      241 ggagaaataa aagtagggaa aagcgccagc ttagctgttt tcagcgagga cctctgtact
      301 gatgactggc aaaaagtgat ggctgcggaa gttatcgcta cctatcttga tggtgactta
      361 gtttacaaga aataatgctt ttcgatataa cgttataaaa cgaattaaag agaggttaaa
      421 aaatggaaac aatgaaaaga aaattcacct tcccacatag ttatacattg atttttatct
      481 taattatttt ggctgcaatt ttaacttgga taattcctag tggtcagttt gagacagttg
      541 ttgaaaacgt cgcaggtatg gaaaaaacaa cggttgttcc gggaacctat caccaaatcg
      601 ataaggcaga ttatggacaa ggtttttcct ctatactaat ggcaccagct gaagggatta
      661 tttcagctgt tgaggttgtt gcttttgttc tcatcgttgg tggtgccttc gggattatcc
      721 taaaaacggg agccatcgat cgagggctgt ttaccttagc aaaagttctg ggagacaagg
      781 ggatcttagt tattccgatg tcgatgattc tattcagctt aggaggatca acctttggca
      841 tgagcgagga agtcattccc ttatttgcgg tgtttatttc tctgatgttt tctcttggct
      901 atgattccat gactgcgatc ttgattctat ttttaagtac acaagcggga tatgttgggt
      961 cgacgattaa tcccttcaac gttttaatcg cacagggagt agctggcgtt tacggaaatc
     1021 ccctgctttg gtttcggatg ctatcctgga ttgtcattac tgggatttca attgttttca
     1081 ccatgcttta tgctagcaga gtcaaaaaga atccactgtc ctctattgtt tatgagagtg
     1141 atttaaaggt taagcataag tttcaaaatt ttgacactga aaaagagttt tcaacacaag
     1201 ataaactaat tatcgccggt tttatcgtag gtttaggaat catgatttgg ggtatcattt
     1261 ccaagggatg gtatatggtt gaaatttctg cactattctt aggattaggt ctttttgctg
     1321 ggggcatcgc tagattttct caaaaggaaa ttgctgaagc ttttgtcgaa ggctgttcag
     1381 atttcgccta tgctgctgta atcattgggc tagctagagg agtcttggta atcttggaag
     1441 gtggaatgat tattgacact attctaaaca gcttggctaa ccttttaggt ggtcttccaa
     1501 aattcctgtt cactacgatt ctactcattt ctcaagtaat tgtttccttt tttgttccat
     1561 cctcctcagg agctgcggca ttaacgatgc cggttatggc accattgggt gatctaatga
     1621 atgtaagtcg tgatgttgtt gttctaagta accagtttgg aaatggttta atgaatatta
     1681 tctccccaac tagtggtgta ttactggcag gattagccat cgcagagatt aatttctcta
     1741 aatggtttaa ggttggcttc aaaatatttg ccatcttaac ccttgtttct gctgttttgt
     1801 tatacattgc tacactcttt tagtcttaat catccattaa taggaggcaa tagttatgat
     1861 taaaataaat caattagcag gaatgaatat ccactattta ttttattctc tcaaagaatt
     1921 tttcgcttat caacagaaaa ttggtatttc ttctgttgaa ctttggggag gtgctccgca
     1981 ttttttcata gatgctttta ctggttctgt tgcaaagttt taaatctact atcaaataag
     2041 gtagaataat agaaaaagat agcaggagga atgacgatga atcattttaa aggaaagcaa
     2101 tttcagcagg atgtgattat tgtagccgtg ggctactatc ttcgttataa ccttagctat
     2161 cgtgaagttc gagaaatctt atatgatcgt ggcattaacg tttctcatac gacgattta
//
LOCUS       DASHWW010000147         2165 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.152, whole genome shotgun sequence.
ACCESSION   DASHWW010000147 DASHWW010000000
VERSION     DASHWW010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.152"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..112
                     /locus_tag="U2R64_002896"
     CDS             <1..112
                     /locus_tag="U2R64_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919636.1"
                     /translation="YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            326..1021
                     /gene="vanR"
                     /locus_tag="U2R64_002897"
     CDS             326..1021
                     /gene="vanR"
                     /locus_tag="U2R64_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEM8919637.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            999..2153
                     /locus_tag="U2R64_002898"
     CDS             999..2153
                     /locus_tag="U2R64_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEM8919638.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          730 a          400 c          461 g          574 t
ORIGIN      
        1 ttatgcggta aagctatata aagaaggaaa tatgactgta aatcaaattt gtgaaattac
       61 taatgtatct agggcttcat tatacaggaa attatcagaa gtgaataatt agccattctg
      121 tattccgcta atgggcaata tttttaaaga agaaaaggaa actataaaat attaacagcc
      181 tcctagcgat gccgaaaagc cctttgataa aaaaagaatc atcatcttaa gaaattctta
      241 gtcatttatt atgtaaatgc ttataaattc ggccctataa tctgataaat tattaagggc
      301 aaacttatgt gaaagggtga taactatgag cgataaaata cttattgtgg atgatgaaca
      361 tgaaattgcc gatttggttg aattatactt aaaaaacgag aattatacgg ttttcaaata
      421 ctataccgcc aaagaagcat tggaatgtat agacaagtct gagattgacc ttgccatatt
      481 ggacatcatg cttcccggca caagcggcct tactatctgt caaaaaataa gggacaagca
      541 cacctatccg attatcatgc tgaccgggaa agatacagag gtagataaaa ttacagggtt
      601 aacaatcggc gcggatgatt atataacgaa gccctttcgc ccactggagt taattgctcg
      661 ggtaaaggcc cagttgcgcc gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa
      721 tgttatcgtc cactccggcc ttgtcattaa tgttaacacc catgagtgtt atctgaacga
      781 gaagcagtta tcccttactc ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa
      841 ggggaatgtg gttagctccg agctgctatt tcatgagata tggggcgacg aatatttcag
      901 caagagcaac aacaccatca ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac
      961 cattgataat ccgaaatata taaaaacggt atggggggtt ggttataaaa ttgaaaaata
     1021 aaaaaaacga ctattccaaa ctagaacgaa aactttacat gtatatcgtt gcaattgttg
     1081 tggtagcaat tgtattcgtg ttgtatattc gttcaatgat ccgagggaaa cttggggatt
     1141 ggatcttaag tattttggaa aacaaatatg acttaaatca cctggacgcg atgaaattat
     1201 atcaatattc catacggaac aatatagata tctttattta tgtggcgatt gtcattagta
     1261 ttcttattct atgtcgcgtc atgctttcaa aattcgcaaa atactttgac gagataaata
     1321 ccggcattga tgtacttatt cagaacgaag ataaacaaat tgagctttct gcggaaatgg
     1381 atgttatgga acaaaagctc aacacattaa aacggactct ggaaaagcga gagcaggatg
     1441 caaagctggc cgaacaaaga aaaaatgacg ttgttatgta cttggcgcac gatattaaaa
     1501 cgccccttac atccattatc ggttatttga gcctgcttga cgaggctcca gacatgccgg
     1561 tagatcaaaa ggcaaagtat gtgcatatca cgttggacaa agcgtatcga ctcgaacagc
     1621 taatcgacga gttttttgag attacacggt ataacctaca aacgataacg ctaacaaaaa
     1681 cgcacataga cctatactat atgctggtgc agatgaccga tgaattttat cctcagcttt
     1741 ccgcacatgg aaaacaggcg gttattcacg cccccgagga tctgaccgtg tccggcgacc
     1801 ctgataaact cgcgagagtc tttaacaaca ttttgaaaaa cgccgctgca tacagtgagg
     1861 ataacagcat cattgacatt accgcgggcc tctccgggga tgtggtgtca atcgaattca
     1921 agaacactgg aagcatccca aaagataagc tagctgccat atttgaaaag ttctataggc
     1981 tggacaatgc tcgttcttcc gatacgggtg gcgcgggact tggattggcg attgcaaaag
     2041 aaattattgt tcagcatgga gggcagattt acgcggaaag caatgataac tatacgacgt
     2101 ttagggtaga gcttccagcg atgccagact tggttgataa aaggaggtcc taagagatgt
     2161 atata
//
LOCUS       DASHWW010000148         2094 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.153, whole genome shotgun sequence.
ACCESSION   DASHWW010000148 DASHWW010000000
VERSION     DASHWW010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.153"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..236)
                     /locus_tag="U2R64_002899"
     CDS             complement(<1..236)
                     /locus_tag="U2R64_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HEM8919639.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNG"
     gene            979..1533
                     /locus_tag="U2R64_002900"
     CDS             979..1533
                     /locus_tag="U2R64_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8919640.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1787..>2094
                     /locus_tag="U2R64_002901"
     CDS             1787..>2094
                     /locus_tag="U2R64_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919641.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     "
BASE COUNT          797 a          239 c          352 g          706 t
ORIGIN      
        1 ccattatgat gcacactgag taattttaaa tcgtaatctt tatcggctaa atagtcgatg
       61 atccgatcct tttcagaagc gatgtaaccg atttcgatgc cttttaaaac acgattgcca
      121 aaacgcttat ttaagctatc gattgtttga ctgtacattt cataatcggg gatatcatcg
      181 actttagtaa caggattggc taagtcaaaa tgttcagtat attttgatga acgcatatgt
      241 agtcctcatt tcttgggaga tttgagacta ctatatgcgt ttttttgttg atttaccaac
      301 atgtttagac attttcctct aggaaaaaat taactagcac cacgggtata ctactatatt
      361 ttaggtttca tattatataa attaataata tactaccatt tgttggtagt ataatttaaa
      421 ggtaataagt tattctttta ttactatgtt tgggttttat agcaaggaaa gtttaataag
      481 agtttggatc tagcaaacaa tattaatgag gtcattaaat cttattatct ttagtgatat
      541 aacgaaatat ctacacagac aaaattatga tcttgcgtaa agttataaaa tatcaataaa
      601 aatattttat taatgaaaag cttggtagca cggttattca tatgctaatt tatttcactt
      661 tatagtaagg ggagttctta gtatattgtt caaacttaaa tttcatataa tttaattatg
      721 taaattagct attctaagaa cttctacgga taattgcccg tctaaaattt aaataagagg
      781 ttagaatctt catataagta aggttaattt ttttgtacaa aaaagtcgga atattctgag
      841 ttactgaaat gatataaaat cataaactaa accccttgat tttcttcact tttaacagag
      901 tatatatata agttcatgat tatggtaaaa tatatatata atcatgaact cagaatattt
      961 ttaagaaggg aaacaatagt gagctataat gtacaaccgt taaggacaaa tgaagagata
     1021 caagattttc agttttggct aagaagaaca agtaatccag aaagagatag ttttttattt
     1081 ttgtttggaa tcaataatgg gttacgtatg tcagatatta taggattaaa agttggagac
     1141 atacgaggta aaagtaagcc tattattgtt gaacataaaa caggtaagcg aaaaccgatt
     1201 tttatagata atttgagaga agagatttta ttatatactg aaggtaaaga agaaaatgat
     1261 tggttatttc caagtcggca acaaggtcga catataacaa gggatcgtgt ctatcagata
     1321 tatgcagata tagcagaaaa attaggaaga gatgatatag gaacacatac attaagaaaa
     1381 acttttgggt atcactacta caagaaaact agagacattg ctaccttaat gtttattttt
     1441 aatcatagct cgcaagcaat tacaaaaagg tacattggta taactgaaga tgaaataggg
     1501 gcatcgttac gtggttttaa attgggaggc taattgagat attaggatat attttttgtg
     1561 tataatgaaa acttagaagg tgagattaat gaagataact gaattttcgg aagtatttaa
     1621 aacgtttagt aacatttaca atagaatacc agagatagaa caaaatgttg tagttgataa
     1681 tgattattat atagagaatg attttaataa accaagaaaa tatgacaacc tatacaattt
     1741 tatacacaat agaacaacaa taaataacaa cagtaacact cgagttttga ttaattcagc
     1801 atattttcat attaaatatt taaagaaata tgagtatgaa gaagttgtat tagattatgg
     1861 gctaaataga cagtcatttt taatttatgc aataaataac ggaaatttgc caagcaataa
     1921 aaagaacata attattgaaa catatgccta tctggagggg ggatctaaaa aactaattaa
     1981 gtcatgtaat atagagtatc aattatcagt aggagaaatt aaatgtgttt tcgaagaaga
     2041 tttagaactt gacttaaaaa aaatttttgc cagcattcat gattatatag gttt
//
LOCUS       DASHWW010000149         2027 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.154, whole genome shotgun sequence.
ACCESSION   DASHWW010000149 DASHWW010000000
VERSION     DASHWW010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.154"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            484..663
                     /locus_tag="U2R64_002902"
     CDS             484..663
                     /locus_tag="U2R64_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919642.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            722..1078
                     /locus_tag="U2R64_002903"
     CDS             722..1078
                     /locus_tag="U2R64_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919643.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT          718 a          275 c          386 g          648 t
ORIGIN      
        1 tattacacca tgaaaaagga agacaacgaa aatgaataag gtgatttatc aactaacaac
       61 ggattccata tcaacgattt gaaagaaaaa aaggtcaata atcatttata ccgaaaagtg
      121 agaatgtgtg aaacaaggac aaaaaaagcc tagtaactaa ggaaatggtt cttatttcgc
      181 accaatcgct ccaaccgccc ccgccgctta ggtggtgcga aataaacggg caaagcccga
      241 taacttaaga gaaagaaggt gatccatttg aacaagatta ttcccttatt gttagtactg
      301 tttgttggcg aaatacttat gcgagatagt gcagctgtac agttaaacct cgctgtattt
      361 ttggtaatac tggtgttttg tttgatcttt tggcggtttg tattagtcct cgtgagtcta
      421 ctattcaaga tgattgcagc catatttttc atagggttat ttcgatgaaa ggagtgagta
      481 ccaatgccaa ttgcaatagg aaataaacgg ttacccgtga cattagatga aaagagacaa
      541 aaagaattgc agcaactaaa gcagaagtat ggcaaaagtg aatctaagat tatgtgtatt
      601 gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg atgtaccagc gctaaaaaag
      661 tgacgtcact ttttaatttg atctatataa gtgatatcac ttttaccaag gagggaatta
      721 aatgttaaaa actaaaaaga attcgtacaa attaaagctt agtatactat ctattatttg
      781 tcttttaggc atgataatta gtggtcattt gtatagagtg gcatatacgc agtttattga
      841 gtacaaggtt cactctttag gattagctgg ggatcgatac gttgaatatg tccattattc
      901 attaaaatgt tcttcatata ttcttctttg gcttattttt tcattgtttg aattgctaaa
      961 tttaatagca atatcttcat atcacttaga taagctaaat accaaatcta gccgttataa
     1021 cgaagtgttt aaggaaaatg tgaagttaga aagtgactta aacaagctaa aaaaataaaa
     1081 agaagaaaac ataagttaac taaaattatt ttattaagaa tgatggaata taaggataag
     1141 gttaccaaca taacgatcat tacttctctg atatgctatg gacttctatc aatcagtatt
     1201 ttgtctatag attatggagt aactatactg caagccttag ttttggctat gcctatgtat
     1261 ctatctttgt ttatcatgca tgaaatatat aagctatttg ttttatcaaa aaatgtagaa
     1321 atacgggtaa atattttggt gaatagttat caaaaagaac tcaaagaaag aagacggtgg
     1381 cggtatttat tgaaaggatg aaaaagtagg atttgacata ctggtattca gaaagtgccg
     1441 tcacttttaa aacaatggaa aaggtggaga taagatgaag aaaaaacaaa ctaaactatc
     1501 attagcagat atttaacaca gttaaccgca actgaagatg gtgttgttga atttgaacaa
     1561 tctgaaattg cggtagtaga tgatcgttac cttaaaatgc cttacttctt tgaccaagca
     1621 aaggtcattt gcctttgtca ctacgatggg gtacgtgatt ttaggcgtta aaaagtagtg
     1681 attatatcaa ctttacgagt aaatataaat ttagacatga aactgaatta tccaatggaa
     1741 aatcatggtt tataatctag aaaaattata gtaatgattg gattatatat attctttcgt
     1801 attttcgtac aactgtagct tgtcaaaatt gagaaattta accgattagg tactttacat
     1861 cgttatttgg gtaatttcta aaacatgaag cttaccaacg aataaactga gactatctta
     1921 ttaattgatc aatataagaa aatatctttg aggagatgat gtactatgtt ttcgtctatc
     1981 cacgattggt taggtggtct tttcggcggt ggaggtaaag gttttta
//
LOCUS       DASHWW010000150         2017 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.155, whole genome shotgun sequence.
ACCESSION   DASHWW010000150 DASHWW010000000
VERSION     DASHWW010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.155"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            99..569
                     /locus_tag="U2R64_002904"
     CDS             99..569
                     /locus_tag="U2R64_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HEM8919644.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            791..1894
                     /locus_tag="U2R64_002905"
     CDS             791..1894
                     /locus_tag="U2R64_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEM8919645.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          686 a          327 c          459 g          545 t
ORIGIN      
        1 aatctctgaa gaataaatca cgtgatcgtg acgataaaat acacttacgt caggtgataa
       61 aaaatacata agtagaaaac taagaggagg aacagaaaat gaaagaagtt caattgatca
      121 gaaaaagcga actatcagaa ggtggttgca atgcatgcgg cgtagtagaa gcaacaagct
      181 atacattaaa gcttggtgcc aacaaagcga taatctctga gttgacagta ggcggtcttg
      241 tggacagtct ggcgcttgct gaaggtttta ttggagaaga tatttatgag atgttttcag
      301 aaatccgtca gttaaaaaaa ggggaaaact gcatagaggt tcatcatgag agcccgaatg
      361 tgagattcaa acgtggtgat aatgagatga tcttcaataa tcatgtgtcc gatcacaccg
      421 agctatatgg aatcgtgaat caaatactaa ctgagctttt tggattggga ccttatgcgt
      481 tcaaggaaga aaacggtaat ccaaaattaa acgaagaatg gcaagaaacg attgaaatac
      541 aaagaaacaa cccgcactta tttcaatagg catccacagt atttcgtaaa agggactttg
      601 acacgacttt tgtcaaaatc ccatcgtttt ttatctattt gtgttctaaa catttctttc
      661 agagtagtaa caactggaat gactgaaatg taaacagatt atttgcctgt atcaatacgg
      721 aagagtaata taaagtgtgt aaacgctatc atattattca ttcaattttt tatagaggga
      781 aggcattgaa atggaaaaaa cgtatcaagc aggtacaaat gaaggaatag tggattttat
      841 caatatggaa gatttagaaa tagccgcttc acaagtgatt ccagctggtg gttatggtta
      901 catcagcagt ggtgctggcg acttatttac ttatcaagaa aatgaacggg cattcaatca
      961 tcagctgatt attcctcatg tattaagaga tgtagaatta cccgatacaa ctacacattt
     1021 tgacaaagaa acgctgactg caccaatcat catggcacca gttgctgctc atggcttagc
     1081 tcatgtgaag gcggagaaag cttctgcaaa aggtgtagca gattttggga cgatctatac
     1141 agcaagttct tacgcttctt gtacattaga agagataaga gaagcaggcg gggagaaagc
     1201 accgcaatgg tttcaatttt atatgagcaa agatgatggg atcaatttgg atattcttga
     1261 agtggccaag cgtaatggag caaaagcaat cgtattgaca gcggatgcaa cagttggcgg
     1321 aaaccgtgaa acagaccgca gaaatgggtt taccttccca ctgccaatgc cgatcgttca
     1381 ggcttatcaa tcaggagtag gccaaacgat ggatgctgtg tacaaatctt ccaaacagaa
     1441 gcttagtcca aaagatgtag aatttattgc tgctcattct gatttgccag tctatgtgaa
     1501 aggtgtccag tcagaagaag atgtctatcg ttcattagaa tctggtgctg gcggaatctg
     1561 ggtatctaat catggtggcc gtcaactaga tggtggtcca gcagcgtttg attcgttgca
     1621 atatgtggca gaagcagtag ataaacgtgt accaatcgtg tttgacagcg gtgtacgacg
     1681 cggacagcat gttttcaaag caatcgcatc aggtgcagat cttgttgcta ttggcagacc
     1741 cgttatttat ggattgtctt taggaggaag tacaggagtc catcaagtgt ttgatttctt
     1801 taaaacagaa ttggaaatgg tcatgcaatt agctggaaca caaacagtag aagatatcaa
     1861 aaaaataaaa ttgcgtgaga atcgttttat ttaagaaaca aatgacgaaa aaaataggag
     1921 tgcggcagat gatgccgtac tcctattttt atagttcaag gatgtcacta atagaataat
     1981 ttgaaacgaa aaaataaaat tgaaatattt tttcata
//
LOCUS       DASHWW010000151         1981 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.156, whole genome shotgun sequence.
ACCESSION   DASHWW010000151 DASHWW010000000
VERSION     DASHWW010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.156"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..196)
                     /locus_tag="U2R64_002906"
     rRNA            complement(<1..196)
                     /locus_tag="U2R64_002906"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(869..1225)
                     /locus_tag="U2R64_002907"
     CDS             complement(869..1225)
                     /locus_tag="U2R64_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HEM8919646.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(1239..1649)
                     /gene="spx"
                     /locus_tag="U2R64_002908"
     CDS             complement(1239..1649)
                     /gene="spx"
                     /locus_tag="U2R64_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEM8919647.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          591 a          379 c          299 g          712 t
ORIGIN      
        1 gattgttata cggtattagc acctgtttcc aagtgttatc cccttctgat gggcaggtta
       61 cccacgtgtt actcacccgt tcgccactcc tctttttccg gtggagcaag ctccggtgga
      121 aaaagaagcg ttcgacttgc atgtattagg cacgccgcca gcgttcgtcc tgagccagga
      181 tcaaactctc ataaaaagtt cgaacaatct tgcgattgtt aagctcaatt tgtttgctag
      241 catattgctt gcttgttaaa aaatgtttgt tgtcttgaat tgaatcaaga cgccctacac
      301 atttggtttg tcttactttg ttcagttttc aaaggtctac ttcatcagga gtgttccccg
      361 attcgttttt ggctgccgta gcaactttta tatcatatca gagagacaag taattgtcaa
      421 ctctttttta aaagtttttt tgatttcgtt tttcgaaatc ttacagcaac tcatttatca
      481 taacttatca tttgttattt gtcaaggact tttttgaagt ttttttcgat agaatcaagc
      541 ttcacaagtg gttctttttt aacaactcag ttatcttatc atgtcatttc taacatgtca
      601 acaactattt tatatgtttt ttaaaatact attttattgc tttgctactt aaaacaacag
      661 aaatgaatat atcatgtaaa tttacacatg tcaatatatt tttaactcta tatccccacc
      721 tagatttgaa ttttgaccac ataaattgag catgtctcta tagtagaaaa ataaagtcaa
      781 aaaaagaaca cataacacgc ttgatgctaa gtgttcgact gttacaactg tatgaaatgc
      841 tcagtgactt gattaaaaca gttaaagtct atttatttaa gataagctgt tccatcaact
      901 gctcattgta tccaataaat agaacttcat cgataataat caaaggacgt ctgaggagat
      961 tggtatgttg tgtgcataaa aaaatcagtt gtttttttcc tacacaggaa aggtcaatcg
     1021 caatgttgtg aaaagcctca gaccaagtcg caaatagctg ttctgcttgc acttcttcaa
     1081 aactgcataa ttcttctgct tcttctgtac ttagatcgcg ttcttctaag tcaacaaatt
     1141 gataaggcaa ttgatggtgt tctaaccatt gtttcgcctt cagacttgtt acacagtgcg
     1201 ctgatccata gactttcact tccacgaagg ctccctccct atgaatttaa gatgttattg
     1261 ttttgtaaat agatcagatt tctggcaaca catcgaattt cacgagggac aaatgaccgg
     1321 atctcatctt cattaaatcc gattagtatt cttttttcat caatcaaaat aggtcgtctc
     1381 aataatgaag gatattcttt gaataagacg atcatttgct ttaaagttaa ttcgttaaaa
     1441 tctatgccca gcttttcgta aattttcgac cgagtggaaa taatatcttg aactcctcct
     1501 tcagtcgctg ccaagatctt tttgatctca ctttctgtta acggttcggc aaaaatattc
     1561 ttctcttcaa attcaagttg attcgcttgc aaccatgctc ttgcttttct acaggaagta
     1621 cagctaggcg aagtatatac ttttatcatt ttctcactcc tttttaatta taatccaatt
     1681 ctacagtaat ttcttttaaa ataccaatta ttagctaata aaatataaaa aaaatcaaaa
     1741 taactgatta tttacgtttg aataatgaga atttttctat atattctcta ttttgataat
     1801 agtattctca ttttcaaaat aaataaggga ggtgtgacaa aattcttgtc acacctccct
     1861 tttccgaata aactgtgttc cagaaatagc ttcttcgaaa ataagctgaa atttcacaaa
     1921 aatttgagaa gcaattttcg tacattcctt cttctttctt gaaactgacc acttctgtca
     1981 c
//
LOCUS       DASHWW010000152         1980 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.157, whole genome shotgun sequence.
ACCESSION   DASHWW010000152 DASHWW010000000
VERSION     DASHWW010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.157"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(325..529)
                     /locus_tag="U2R64_002909"
                     /pseudo
     CDS             complement(325..529)
                     /locus_tag="U2R64_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(729..1745)
                     /locus_tag="U2R64_002910"
     CDS             complement(729..1745)
                     /locus_tag="U2R64_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEM8919648.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          558 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaaa attttcctaa ttgtgacatg gctgtcacaa
      541 ttccaaatgc tctccgaggg tattcgctgt cacaagtgac aacgaaaaaa ggagccgaaa
      601 gcgtgtcacg ctctcaactc cttttacgct ttattttgct tcatgcaaaa tattcgctta
      661 tcgtgaattt acgtcactaa acattgacgc aaatccactc tcactcatct gacttttctt
      721 attcggtatc acttctctgt cacatccaac cccaaaagcc acgtatccaa ttcttttttt
      781 aattcgtctg cagattcctt aaacgtctct cgtaaatgat tcgttaactc atcattttga
      841 ctttcttgct tcagcaaatt ccgatattta tattttgtat gtctagcaat tatcgaccaa
      901 ttagaaggct cagctatcaa accatcaata actattttat caataggttt tatatcaatc
      961 ggcaaaaaat gcgggcttgc aaaactatct aagctttcct gaaccatcgc atgccaatcc
     1021 gttgctttgc cacgtcttag ctgcatttct aaccgccacc acgtatcgat ttcttttggc
     1081 acgattactt tttttcgttc ctgctctagc tttttgttgt acagtcgcac ttggcgctca
     1141 ctggcacgac tgccccagta cgctgtttct agcttgccag aacggccgta gattggctta
     1201 aaagaaatcg ggtctacaat acgatactga gtaataaagt catccggcac atctacaata
     1261 tcgcaggcaa tatccgcccg ggaaaaatgc ggatctaaaa ataggtcatg aatgaatcct
     1321 ttcatggaac tagctaaaaa ctggcctatc ttattcggat taaaatcaat acgacctttt
     1381 ccttcatgaa atttaagtat ttcgatatac gcaatatctt ctccatattg atcgaataat
     1441 tgccagccgt ttatcccaac tgatttcaaa tatccctgat tttcgttcaa acgcattaat
     1501 tgctcgaaat cgacaaaaac aactccattt ttcgtccaat aagctatggt atcattcagt
     1561 tttccgacaa ttgtaattcg atcaatcgac caatttaatt ttaggggggt ggtcgtacct
     1621 tgcacactta accgcctgtt agaaatacgg ttaagttttt cgagctgatt tatcgttgtt
     1681 cttttttctg cccctcgacc ttcaattttt gattgaattt cactcaactg attttcattt
     1741 gccattttcg tcctccaaac gaaaaaagag acttttggaa agaatttcca gagttcacgt
     1801 aaccctaaaa attcatatcc aaaaatctct agcttgaaga aacctaaaaa tattcgtata
     1861 atgaacctga gttacggagc taggtgaagt agtttccgta aatagtcgag agtgttagcg
     1921 cactgctcgg cttttatttt gctctttttt ctcgttttct ttgattatag cactcctcct
//
LOCUS       DASHWW010000153         1972 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.158, whole genome shotgun sequence.
ACCESSION   DASHWW010000153 DASHWW010000000
VERSION     DASHWW010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.158"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(62..241)
                     /gene="rpmF"
                     /locus_tag="U2R64_002911"
     CDS             complement(62..241)
                     /gene="rpmF"
                     /locus_tag="U2R64_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEM8919649.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(299..868)
                     /locus_tag="U2R64_002912"
     CDS             complement(299..868)
                     /locus_tag="U2R64_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEM8919650.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1054..1956
                     /locus_tag="U2R64_002913"
     CDS             1054..1956
                     /locus_tag="U2R64_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8919651.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
BASE COUNT          587 a          419 c          332 g          634 t
ORIGIN      
        1 aaaataaacc tcaaggctcc atggttagcc ttgaggtttt acattttcta attaaaatgt
       61 attaagcttc ttttgacatt acgtccttac catcatagta accacaattt gcacatacgt
      121 gatggctttt tttcatttca ccacagtttg gacattcgtt taaccctttg attgtcaatt
      181 tgtagtgtgt acgacgtttt gcttttttag cttttgatgt tcttctagct ggtactgcca
      241 ttttgctaca cctccttgta aagtcttgta tctaaattag acacaatata ttccaatctt
      301 acttgttatc gtcgtctttt gatttagaat caaaaagttc agatagtttt gcaagacgag
      361 gatcaatttt attctcggct tcttccattt ttctgcgctg gtattcttct tcggaaacaa
      421 cttcccaatc attgcctttt ggaagttctg ttgctgcttc ctcttctttt gtcaataccc
      481 gcattggaat cgccaataag atgttgtctt caatcgactc tgctaaattc aataatggac
      541 cttcaattag caaaatctca tctgcagaca tttgttcatc tctactttgg aattgttctt
      601 ctgtcatgaa tacttcgtct acagaaaaat ccatgggcag ttcaacaggt tctagtgaac
      661 gtgttgaagg aactgtcaaa gtcgtctgca cagtgtaatg aacgatatag cctttcttat
      721 caactgagac caaaccttcg acttccactg gcgcaacatc aagtattaaa ttgtctcgct
      781 tcatgagagc ggctttcaag tcgagcgtct catgaaaagt taacggtgtc tcctggtatt
      841 ttctcaattc caataaagac catttcattt ttcatcactc ctaagcaaca aaagcaatta
      901 tacagggcaa aaagcatgtt gtcaatgaaa ttttcttgac accttgcagt tcataaaaaa
      961 acagaaaaat ctttattaga aagcctctgt ttgctatcat cctcagaatc atttacaata
     1021 atcattattc cattaaagga gcggatgatc ttcatgaaca cgaaagatat cgaatactat
     1081 gtccaaatcg tcaaacaaaa aaattttacg aaagtggcta attatttccg tgtgagccaa
     1141 cctactatta catatgcatt acaacgtctt gaaaaagagt ttgacaccgt acttattaca
     1201 agagatcgat cgcatcacga attaatcgtc acgccttctg gaaagcagct gtttctccat
     1261 gcacaaacca ttctccaaga gatttctact gcaagagctg aaatcactca gttgcaaaag
     1321 aaaaagcttc gttttggcat gcctcctatt atcggcaatg aatactttcc taaactgtca
     1381 agttacttta tcaagcatga attgatgaat caaattgaga ttaccgatgg aggctctcgg
     1441 gacttatacg ggatgatccg acaagggagg atcgatttag ctgtattagg ctcaacacag
     1501 ccaatcgtgg atcaatattt agaaacagag ttacttttgg acaaacgttt catgatcgtc
     1561 gtgccaccta cacatcctct ttccaagcag gatactgtct ctttcaaaga tatagcagat
     1621 gaacagtttg tactattgaa cgaacattat gtccaccccg cagcattcac taagctttct
     1681 aaacaaacac atactcatcc aaaagttgtt tatcaaagca atgacttgac gattttaaag
     1741 agtatggtcc gagaaaatgt gggtatcggt tttttggcag agattgctgt ccatcctgaa
     1801 gatcatttag tttgcctccc tctttcagat gaagttcagc ctcgcttctt gatttcattg
     1861 gcaaaacgaa cacagcagat cgtcacgcct cttcaagaac aagtagtcca agttatccat
     1921 gaattcgtta cagcacaaaa aaacagctct tcgtaaaaga agagctgttt tt
//
LOCUS       DASHWW010000154         1834 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.160, whole genome shotgun sequence.
ACCESSION   DASHWW010000154 DASHWW010000000
VERSION     DASHWW010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.160"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            895..1834
                     /locus_tag="U2R64_002914"
                     /pseudo
     CDS             895..1834
                     /locus_tag="U2R64_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          676 a          306 c          320 g          532 t
ORIGIN      
        1 ttgcatatca ttttcttcgt aaatatcaaa atcatgttaa ctactatcaa ttactaataa
       61 aaactaccac tttaagcgtt aagaactgtt aagtttagtt aagtgaggat agttcacaaa
      121 atccattgtt aaacttcacg aaagtggtaa aactcaaaat gctttatata ggattacagc
      181 atcgctcttt cttcgattgc gcgttgggta aaaaatatta tgaagtaaaa attgacgatg
      241 acacgttcct tacggctcat cagatgaaac agctacaaaa acgaaatgat caactcgaag
      301 aaaatttaat tctaaaaaag cgattgccat attcacgcct cgctcgacga actattaaag
      361 gtcaagattt acctgaagat catccttttt aggaaattga agctttttat gttgcacaat
      421 gcatttataa tactacaatg atgttttcac cagatattct tctagggtgc ggtgtaatga
      481 aacagataca cttgcaaaag aaaattcacc gcgaatttac taaaattatg aataattatg
      541 ttaatcttcc gaaatttttt tccaaaatta agggatcaag ctggtgttat agattgttta
      601 aggttggcaa aaaaataact tctttttaaa caattataga aaaccgatac tctgttaagt
      661 tggttgacac ggtgtcgatt tttatgactt tcttattctg aaacttcact aacggacagt
      721 acctaaaaag tctatagtat ggacgtttac gagtactatt ttatcaaaaa tgctgctcat
      781 ttcaacttat atgttttagt gaactacccc cacttagctt ggataggcta caattaacta
      841 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
      901 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      961 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
     1021 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
     1081 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
     1141 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
     1201 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
     1261 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
     1321 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
     1381 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
     1441 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
     1501 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
     1561 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
     1621 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
     1681 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
     1741 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
     1801 ataaaggctg tccttttgat aatgccgtag ctga
//
LOCUS       DASHWW010000155         1805 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.161, whole genome shotgun sequence.
ACCESSION   DASHWW010000155 DASHWW010000000
VERSION     DASHWW010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.161"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..85)
                     /locus_tag="U2R64_002915"
     CDS             complement(<1..85)
                     /locus_tag="U2R64_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8919652.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
     gene            360..902
                     /locus_tag="U2R64_002916"
     CDS             360..902
                     /locus_tag="U2R64_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919653.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1058..1507
                     /locus_tag="U2R64_002917"
     CDS             1058..1507
                     /locus_tag="U2R64_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEM8919654.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMAPIALDNEHPRI"
     gene            complement(1537..>1805)
                     /locus_tag="U2R64_002918"
     CDS             complement(1537..>1805)
                     /locus_tag="U2R64_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8919655.1"
                     /translation="SLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLAQLRLELFDY
                     VHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          657 a          264 c          349 g          535 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcaa attgatgaag cagatcccaa
      181 agggctgctt catcaatttt ttcgtaagtg tccgtacact tactgtgctt gctcatatat
      241 taatcgatca tatactaatc gtgtaagaac aactttaagc ataatactta tattgttata
      301 ccatagtttg gaaaaataaa aaattatatt tcatcaacgt ttcataaaag gtgtgtagaa
      361 tgttattgaa agtagctata aaatgctatt gtgtaaaaaa taaaggagga ataatttatg
      421 aaaaaatagt accaagagga gcatgcctat tacttgcatt atgtttgagc ttaagcgcag
      481 ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga aggacaatcc ataagttctg
      541 aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga aacttttaag ccatcagatt
      601 atacattgga ggcaaagaaa gaatatgttt atgaatattt agggcttaaa tttaaactct
      661 cagacaaatt tagaaattat atagctgata aaaagatagc gatgttagat gatcaaagtc
      721 ctatagataa agaactaaag tatgctattt tgacatttga gaaaatgaca gaagaacaaa
      781 agaatgcagt tatagaaaag atgggcgatg gatataaaaa ttggcaaaat gagcttgaaa
      841 gaattgggac tattggtata tttgaaaaaa atacatcaga agaaaaaaat ctaaaattat
      901 aaaatgtgat actcatacta aaataggagt ttcaagtgat ggaaaatacg attgctattt
      961 aagcacaaat agcggagctg aaagtaatct tcttgatgaa ttaaaaagaa ctgagattca
     1021 aattatagat aaaaaagaac gtcctaaaaa tggttttgtg ctatcagaaa aaactgattt
     1081 agaaaataca gaagcattta acaaagaatc ggttaaagat ttacgtaaac taccaacaaa
     1141 ggacataaat ggcaaggatt ttacaagtaa agattttgag aagtatgatc ttactatggt
     1201 aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa attcctgatt tggttgaggt
     1261 tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga gttgttacag atcctgttga
     1321 tgataacggt gaaaacaagg aagcaattga aaagtcaaag ttaatacatg aaaagacaaa
     1381 ggcttcatat cctttcttaa tgccagatgg aatggcaaca ctttttttga caaaaattat
     1441 aaggtgttgt gaatgctgcg gtgttatggc tccgattgcc cttgacaatg agcatcctcg
     1501 gatctgattt tctccggcag aagcacaatc attcaattac gctgcctctc cagaggtatc
     1561 agatccgcgc tcattatcaa ggattcgctt cgccaatctc tgttgtcgaa tttggatcgg
     1621 tgtttcatac gccaacgtgc catgtaagcg tagatagttc caccaatgca cataatcaaa
     1681 caattctaga cgtagctgtg ccagtgtctc aaattggtat tgatgcacga attctacttt
     1741 gacagattta taggttgatt ccacaacggc attatcatac ggacaaccct tcctactcaa
     1801 tgaac
//
LOCUS       DASHWW010000156         1803 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.162, whole genome shotgun sequence.
ACCESSION   DASHWW010000156 DASHWW010000000
VERSION     DASHWW010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.162"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..895)
                     /locus_tag="U2R64_002919"
     CDS             complement(<1..895)
                     /locus_tag="U2R64_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEM8919656.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASD"
     gene            complement(895..>1803)
                     /locus_tag="U2R64_002920"
     CDS             complement(895..>1803)
                     /locus_tag="U2R64_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919657.1"
                     /translation="AYSLCVEKINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLR
                     TDKLKISKELNEQLNKLYQTTTEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQE
                     EKQRQKEKEREQLEIRKREQDLAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQA
                     QLNYLAQPQPTPSVAAVQTPMNNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAF
                     NHINQSSQADSVATTTSIKEEAQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDP
                     SKAKEGSSDSTVQSNTSESSESNEVK"
BASE COUNT          445 a          351 c          308 g          699 t
ORIGIN      
        1 tgtctgaagc gttggcatca taataaatcg tattcgtgaa agtattggtt aactgtgtcg
       61 ctgtgtctat gtctcctcgc ttccagtatt tcacgatgag tgccaatgga ttatcactca
      121 ttgattgcag tggatcggtg atattaaatg catacacatc ataccctcta gcttctagtt
      181 catctttact agcaacatat aattctgttt ttggatcatt aacaaccatt gaactttgtc
      241 tttctgcacg agacaaattg tcaatggttg ctaaaacttc tatctgtcct ttccctgaac
      301 gggaagtacc aacaatacaa gtatttactg tatccgtctg aatataccag tactttttat
      361 aatgagtaat tggtattccg ccataaccag gaaaacctcc ctttgattct ggtatttgcg
      421 gataaatttg ttggatttcc tttaacgttt ttaatcggtt atctcctttt tgcccatctg
      481 ctagaggacg aaaccacatg tccattttca atcccataag tacagctgga acaacacaaa
      541 tcgtagaaac aactaaacgt gtgcctaaac ttgttgttgg ggtcaaagga ttccaaaaac
      601 cagttgaatc aaaatggaat aactgcggca tttcttgtaa ctgaaaaata ttcactcctt
      661 gtaaacttcc tggaataatc tcaaatcgat gaaatgcttc tggtattctt gtaacaacat
      721 agtttaaagg aagataagct aagccactat aaaaaatctt ttgagaaata cgtttgtcat
      781 gtttttctgg tagctcttct cctgaaggag tatagcgata gaaatgagaa agatacctat
      841 tcttttctaa attgaatcgt ttgtcttttc gtctcgttgt ttctctaaca cgcattattt
      901 cacctcattt gattctgaac tttcggaagt gtttgattgt acagttgaat cgcttgatcc
      961 ttctttagcc ttactaggat cactctcttt gctattttcc atacttgatt ctgttgttga
     1021 ctgattggta cgattcaata attcttctaa ttgttgttca tactcttttc ttgcttgttc
     1081 ttgggcttct tccttgattg acgtcgttgt ggccacagaa tcagcctgtg aagattgatt
     1141 gatatgatta aaagcaaata ctgttcctcc acctagaagc aagcttaaac ttgcaataca
     1201 tcccaccatc catccgttaa aggaacgctg tggtgaagga gttagatttg tttggttgtt
     1261 cattggggtt tgaacagcag ctactgaagg cgttggttga ggttgtgcta gataatttaa
     1321 ctgagcttgt cgcaatgtat ccatttgttc ttgacgttcc ttacgagcag ctgcttcttt
     1381 ttccttttct tgctctaacc gttgtttttc tatcgccatt ttttgttccg caagatcctg
     1441 ttcccgtttt cttatttcta attgttcacg ctctttttct ttttgccgtt gtttttcttc
     1501 ttgttctttc aattcttgtt gttgaatttc atactctttt ttccattttg gaatttgtac
     1561 ttgtaattct tgctggatct gttcgtgttt ttccataaga acttcagtcg ttgtttgata
     1621 tagcttattc agttgttcat ttaattcttt gctaatcttt agcttatctg tacgtaaacc
     1681 gcggtagaac tcttcttttc gttctttaat acgttctttt aacaagtttt ctttttcttt
     1741 cgataacgct tcttgattcg tcttagtaaa attattgatc ttttctacac acaaggaata
     1801 agc
//
LOCUS       DASHWW010000157         1778 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.163, whole genome shotgun sequence.
ACCESSION   DASHWW010000157 DASHWW010000000
VERSION     DASHWW010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.163"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..1031
                     /locus_tag="U2R64_002921"
                     /pseudo
     CDS             1..1031
                     /locus_tag="U2R64_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          607 a          333 c          294 g          544 t
ORIGIN      
        1 ttggttttaa cacggggaat tctcgtaacg gctcctatga ccgtacggtc aagaccgagt
       61 acggggaact tcatctccag attccgcgcg accgcaacgg cgagttcaag caacagactg
      121 ttcctgctta tagacggacg aatgatacct tagaggagac cgtcattcac ctcttccgaa
      181 aaggtattac catgtcggaa atcgcagact tgattgagaa aatgtatggg catcactaca
      241 cgccccaaac catgtccaac atgactaaag tgctgactga agaagtaaat gcatttaaag
      301 ttagaactct aaatgataag tatgtcgcta ttttcatgga tgctacttat attcctttaa
      361 aacggcaaac cgtctccaaa gaagcaatct atattgccat tggtatacga gaagacggca
      421 ctaaagaagt actaagttat gcgattgctc cgactgaatc gacctacgtt tggaatgagt
      481 tgttacagga catttactcc agaggggttc atgatgtctt actgtttatt accgatggct
      541 taaaaggcat gaaagatacg attcaccaga tttatcctaa agctaaatac caacattgct
      601 gtgttcacgt ttcccgtaat attgctcata aagtacgtgt caaagatcga aaagaaatct
      661 gtgatgattt taaggctgtt tatcaagcta gctcaaagga agaggcaaat acctttttag
      721 ggagtatgat tgagaagtag caaaaaactt atcctaaagt gacgcagtca ctgataaaaa
      781 atcaagattt attgactttt tatgagtttc cgcctggtat ccgccgaagc atttactcaa
      841 ctaatttaat cgaatctttc aagaaacaaa tcaagaaata cagccgcaga aaagagcagt
      901 ttcaaaatga agaatcacta gagcgtttcc tagtatccat ctttgataca tacaatcaaa
      961 aattcttaaa tagaagccat aaaggcttcc aacaagtgac ggatacatta gcttcaatgt
     1021 ttactgagta acccattatt ttgcagaagg acgagttatt tacacaaaat tattgacgct
     1081 ccctccaaat tacttcatca aaacattgat ataattttta ttatatcagt atttattctt
     1141 gatacataaa tgagaaaata aatactttaa atctattgac tacaagtagt cattaagtct
     1201 tcataagatg tacaatatga cattaaaaaa ataaaagctt acgaccatcc gttaaatctg
     1261 acactaaata atggactgct ttcttttgta ttagcaggtt acgttgacta tgaatattca
     1321 ccagattatt tggagaaacc tcttcaacac gagaacaatg atattaattt tagatttgtc
     1381 tacgagtcaa aaagtaaaac atggttagtt gatcaattaa gcacgataaa cacaagcttc
     1441 catgaattac ctaaacctga aaatgaagtt gagatggtca ttaaaatctt ctaaaaaaga
     1501 agcgttgaag gggaaatatt cctttcaacg ctctttttta tatgcttaga aacataaata
     1561 aattgtatac tttcttttta gcccctatta cttttcacga aaaatatctt tttttcgacg
     1621 ctagcgtttc tctacttcta atactgtaca cagtttttgt attattgaaa aattactcat
     1681 tatttagcat taatccacat cgttttatca atcgaccttc atactaaact actttaaagt
     1741 catcttcctt ctcgtttttc attaatggaa tggcaaca
//
LOCUS       DASHWW010000158         1755 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.164, whole genome shotgun sequence.
ACCESSION   DASHWW010000158 DASHWW010000000
VERSION     DASHWW010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.164"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(192..569)
                     /locus_tag="U2R64_002922"
     CDS             complement(192..569)
                     /locus_tag="U2R64_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919658.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(869..1750)
                     /gene="galU"
                     /locus_tag="U2R64_002923"
     CDS             complement(869..1750)
                     /gene="galU"
                     /locus_tag="U2R64_002923"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEM8919659.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          503 a          382 c          255 g          615 t
ORIGIN      
        1 aaacattggt atgatttata tatatataaa taacataaaa aaaggaatgg cttatcccga
       61 tacaacaagc attcctttaa aaaagattct tttatataag tgaaaaaagc ttttttccac
      121 caattaaata aatctctcat ctcaatagtt tatccattat tttatctttt tttgcgtata
      181 cctactaaat attaccgtct tcttctcgtt cttctacttt gttcgagaga atctgtacta
      241 gaaaaagtag ttgtatgtct accttttctg cctatccgag actttctttt catatatggg
      301 atataaatga ttagatacag tacagcaaaa aataaagcaa atacgcaagc ttcccaacta
      361 cctaacgcca attcaaccat caaggtagca accccaacgg atgctgcata ccagataaaa
      421 atcagaaacg tttctttttt tctgaccatg cgaaacatga taaatagact aataagcaat
      481 agtggcaaca caaatatcca attgcttcct tccatcagcc acttgagtat atcaagcagc
      541 gactgtgcaa cagcgactaa ttttcccata gtgaacacac accttttttt ataattaaaa
      601 aattcgcctt tttattctac tatgaatctt ctggcttggc tttcatttct cttatgtaat
      661 cattttcttt tatacaactt aaaaaaaaat taaaccatta gcataatatt ttctgaatct
      721 attcacgaaa gtctttttct atctttcgtt ttccacgact caactgatct agagtcaaaa
      781 aactaaaacg acagttgcgc aaatgacgca caagctgccg ctttaataac aaatagcctt
      841 tcattctcag caggccactt atttccagtt aactttctgt tcttagcttt ttactcaact
      901 ggataatata tgcacttaat gaagtcccaa tttccgaatg ttgaagtcca tattcaatat
      961 ttgtcttcat atatcctaac ttatcgccta cgtcgtatct ttttccttta aactctctcg
     1021 catagaccgc ctctgtctgg ttaagagtct gaagtgcatc cgttagctgt atctcgtttc
     1081 ctgctcctgg ttcttgagtt tctaatatct caaatatttt aggagtcagt agataacgtc
     1141 cgataatggc taaattactt ggtgcttttc ccatttcagg tttttctaca aaccctttta
     1201 ctctgcaacg acccttttcg ctatctgttt taggatcaat aattccgtat ttagatgttt
     1261 cattttctgg tacacgcatg acggcaacag cggaagcttg tgtttcttca taatccatca
     1321 tcaattgttg agtcaatggg atatcatctt tcatcaaatc atcccccagc atgacgacaa
     1381 acggttcatt tcctataaat gcttttgctt gaagcacggc atcccccagt cctcttggat
     1441 gagattgacg gatgaagtga agattgactt gagtcgtttc ttcaactaaa gcgagtaatt
     1501 ctgttttttc cttttcccgc aaattgtttt ccaattcgat atttgcatca aagtgatctt
     1561 caatgggtct tttttctttt cccgttacga tcaagatgtc ttcgattccc gaatccaatg
     1621 cttcttccac aataaactgg atcgttggtt tatccacgat tggaagcatt tcttttgcca
     1681 tggcttttgt tgccggcaaa aaacgtgttc ctagcccagc ggcaggaatg actgcttttt
     1741 tgaccttcac ttgct
//
LOCUS       DASHWW010000159         1685 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.165, whole genome shotgun sequence.
ACCESSION   DASHWW010000159 DASHWW010000000
VERSION     DASHWW010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.165"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(45..779)
                     /locus_tag="U2R64_002924"
     CDS             complement(45..779)
                     /locus_tag="U2R64_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEM8919660.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="U2R64_002925"
     CDS             1106..1516
                     /locus_tag="U2R64_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HEM8919661.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..>1685
                     /locus_tag="U2R64_002926"
     CDS             1509..>1685
                     /locus_tag="U2R64_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEM8919662.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          536 a          294 c          325 g          530 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataat
//
LOCUS       DASHWW010000160         1677 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.166, whole genome shotgun sequence.
ACCESSION   DASHWW010000160 DASHWW010000000
VERSION     DASHWW010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.166"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(366..1658)
                     /locus_tag="U2R64_002927"
     CDS             complement(366..1658)
                     /locus_tag="U2R64_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8919663.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
BASE COUNT          516 a          342 c          285 g          534 t
ORIGIN      
        1 gtatgggcta ctctgtgata cttattagcc attaaactat tttacccaca tagcatatat
       61 tttgaaatcg ttcattccgt aaattcaact aaatatgcct aaaaaaataa aaaatctaag
      121 atagaataag atttattcag tcttagatgg atttatagca actttttcgt aacaacttta
      181 aaaaatacga aaagaaagag ctgttttact ctgactacgt tgctaaattg tcgtttaatc
      241 attcatttaa accaaatctt tttttataga attcgtttta atcctcctga atccaaaaac
      301 tatgaaaacc gtaattaaat agttaagagt ttttaaccac cataattctc tcggctattt
      361 tgaaatcaga taaattttga tcggacacat agttgaataa acctaccgtt gttacggaag
      421 gtaaatcgca tacttttcat tctagaggag aaggtctcgt tgatcattaa ctgattaagc
      481 accatagccc agttttgaat tcgaccacct gaccacttcg cgtgtaattc tttcgtgcgt
      541 aaataaagta gttttaggag tgcattctca ttagagaacg ctcctttttt tgtgactttt
      601 ctgaagctgg agtggacact ttcaaccgca ttggtagtgt acataatttt tcgaatggca
      661 ctaccataat caaatagttg ttcaacatgt gcaaagttcc gtttccagac atctacagca
      721 ccagaataat gagaccaccg attttgaaaa ctgtcaaaag cagcatgtgc agcgtttaga
      781 gaagaagcac cgtagaactt tttcatatct cggcagactt ccttatagtc cttacttgga
      841 atatagcgca atgcatttcg aacaagatga acaatacagc gctgaacaat taccgatgga
      901 aagatcgctt ttgcgccttc ttcgaggcca gaaacaccgt ccatcgaaat gaaaaagaca
      961 tcttcgacac cacgtgcttt cagttcatca aatacttgca tccagcgatt tttagattct
     1021 gtttgattta accataatcc taaaatctcc ttatttcctt tgagatcata gccaagaatg
     1081 gtgtatacag catattcttt ggcttcataa ttttctcgta aagtaacata catacaatca
     1141 acgaatagaa aggcataaca ctttgctagg gggcgggctt gccattcttc caattcagga
     1201 aggacagcgt cagtgatatc tgaaatcatt tcatgggaaa tatcaaagcc ataaatagct
     1261 tcgacggttg cggcaatatc tcgttgactc attcctcgtg catacatgga aagaaccttc
     1321 ccttcgatgt cggagacatc tcgttttctc ttaggaatta actctggttc aaaggaagct
     1381 tcccggtctc taggaacatc aatagctact tcaccaaaac tggttttaag cgttttagtt
     1441 ccatagccat ttcgacggtt atcgtgttcc ttaggctctt tagaatgggc atcataacct
     1501 aaatgattat tcaattctcc ttgaagcatt ttttcaaaaa ggggcccaaa cacatctttc
     1561 aaagcatctt gcatgtcatc gacagattca ggttgatagg cattcagaat ggattcagct
     1621 aacttttcgg catcaggatt tcttttcttt ctagccatcg tgtaatcacc tcttgat
//
LOCUS       DASHWW010000161         1636 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.167, whole genome shotgun sequence.
ACCESSION   DASHWW010000161 DASHWW010000000
VERSION     DASHWW010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.167"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(183..1502)
                     /locus_tag="U2R64_002928"
     CDS             complement(183..1502)
                     /locus_tag="U2R64_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HEM8919664.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          525 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaat
//
LOCUS       DASHWW010000162         1615 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.168, whole genome shotgun sequence.
ACCESSION   DASHWW010000162 DASHWW010000000
VERSION     DASHWW010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.168"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(53..937)
                     /locus_tag="U2R64_002929"
     CDS             complement(53..937)
                     /locus_tag="U2R64_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEM8919665.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1032..1469)
                     /locus_tag="U2R64_002930"
     CDS             complement(1032..1469)
                     /locus_tag="U2R64_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919666.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT          518 a          329 c          246 g          522 t
ORIGIN      
        1 tatcccgaac aagcggtgtt ctcccgccaa ctcctcggtc acaacctcca ttttaacaat
       61 aaacctgtaa atgtgagggc aatactttga ttgtcacagg taatttatcc ccttcatctc
      121 catcaacatt cgtcgtcaat tcttcctcat cagctaatga cacaactaat tgctcacaag
      181 taaggtaggc tagatttttc gtagattcat ctactccttt taataggtct ggcaatgttt
      241 taagcgtatc gatcaaagaa gaatctttta aataaaccaa atggagctta ccatcatcca
      301 cttttgcatt tggaagtaat gtttcaaaac cgccgactga gttagttagt cctatcagca
      361 aggtactgct ctcaatttct tccttctttc catcaacttc tacgtgaaac gagtaggatt
      421 gtgtggaagc taactgtttg attcctgaca tgaaataagc tagttttcca aatttcgtct
      481 tcttctccgc atctacatca ttgattgatt cagggataga gccaattgcg acgacattca
      541 taaaatagtc gtcatttatt tttccaatat ccaatggctt gactgattca atcgaaaaat
      601 gattgatcgc ttcctcaggt tctagcggta tccctaatgc tcgagccaag tcattcaccg
      661 tacccaatgg gaaaaatccg aaatttggcc gatgttcttg ttcagcgatt ccactgattc
      721 cttcgttgac tgttccatct ccgcccatga caaacacact atgataccct tccgtagccg
      781 cttcgcgagt aaagtttttt gcatcccctg ctttttttgt atgcaagacg accacttcat
      841 caaacaccga ttccaatttt gctatcgcta attgctcaaa ttcctttgct tgttcaccgc
      901 ctgaactggg gtttaccact aataaaactt ttttcatcac tttctttccc ttctgattga
      961 tttctttaat ataacgatag cataaagaaa aaaattaggc tgtgatgaag tactgttcat
     1021 gaaacattca tttatttttt gacaagataa aacatccata ctatgaaact gaggaaaatt
     1081 aaaacaatga tataggaaat aaaagaaaat gataggcatt gtatacctaa taaagtaaaa
     1141 atcttaggtg gcagataaaa acacaaaaat agcaagagaa tgtaatagcg tttcttccac
     1201 tttttgttat cagaccttat agcgatcaga ggaataccaa atgcataact gaaaaactct
     1261 tgatgtactg ttaatatgtc acggccttga ataataaatg cgacaatccc cgctataatt
     1321 agtgtgccta acaccaaaac ggaaaattga tgaatatatt ttatatacaa atgatccatt
     1381 gtacttcctg cctttttatt tgtgagaaaa acaaatccgt atacgtgaat aacttctaga
     1441 aataaaagaa atttgcaaaa ccactccatt tatctacttc tacgtgcatt ttttgatatt
     1501 gttttcttta tttaagatta tacagaaaaa tatctagggt cgctggattc taagtaaaaa
     1561 aaatttttaa aataaaaaga actaaatcaa gtagtaatta aactactgtt gattt
//
LOCUS       DASHWW010000163         1613 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.169, whole genome shotgun sequence.
ACCESSION   DASHWW010000163 DASHWW010000000
VERSION     DASHWW010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.169"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(583..1197)
                     /locus_tag="U2R64_002931"
     CDS             complement(583..1197)
                     /locus_tag="U2R64_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8919667.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          527 a          298 c          253 g          535 t
ORIGIN      
        1 tgtttttcct taaaattctt tttttatttt tagattagag aaaatctcgt cctgtttttt
       61 tcattttaca atcattgaaa aattgaattt cattgcaaaa aaaataataa acacttataa
      121 atatccatta tctatccttc aatttttgtg tattttattt ctattagaaa aaggtatcct
      181 gttggacaat tttgttatat caggtaaact tcattgcaat aatgataaca aatgtactat
      241 aattactttg taaagagttt tggggaagac tctttcatca acgtgtatta agagacaaga
      301 aagaatccat atggattctt tcttgtctct ttttccacta ctttttattt ttctgacact
      361 acatattctt ataactcatt tctcataact gtgaaacaac ttataaaaat aacaaacttt
      421 aaacaaaaca agcttaaaat caaagatgat ccatcttaaa ataactaaaa caaaaaaagt
      481 agtcgttgtt aatcctcatt aataatcgtt ttcttttttt caaacgctcc atttttatgt
      541 ggaacattat ttttttaagg aactttgtca acatgtggat aactattttc cacttgtgtc
      601 ctggactagc tgttttgctg taaaatacaa aacttgctgc agcaaaaaga tcgttgcaag
      661 agaggctgtt ccgcagatcg ctggatctag atttggcaaa gtcaagactg catcatgtaa
      721 attggcgtgg ttgtccaaaa ccaaatcagc aaattcaaat aatcgcaaac cactgctatg
      781 ttgcgatttg atacttcgtg acaaatcaaa tccagtaaca atgattaatg gatgaccatt
      841 ttctttgatc cactgagcta gttcgatgat tgccgggttt cttccttcat tcgaaagaag
      901 aagaaaaatg tcttctgatt tgacagaaag ctgatcaata attgcctgtc ctgcaccttc
      961 tagcgtttca tagacacctc cggctggatt ttcaatcaat atacttggta caagatccgg
     1021 ggtttgatcc caaaattcaa atgctacacc acttagtgtg cggctagcat atatctgcaa
     1081 tctaccacct tgattaattt gtttcgcgat ccaagtgcca gcttgaagca tcagcggctc
     1141 ttctatcctt aatttctctt ccaattggtg ataatagtca aaataacata aactcattta
     1201 tctctcccgc ctagctatac ttgacatgaa tagaaacagc tgcctaatct aaggaagtac
     1261 ataaaaaaac agtagttaga cagtaacaca tgtggtcttt gctgtttcaa acacaaaaaa
     1321 ggcattgaac gaatacgccc aataccttga catagcaaat aaaacaacgt gcagaccatg
     1381 gaaaatatct acataggggt agaattttca ccctagatta ggtacaataa attaggtcga
     1441 tgcactgcat tgactatggc aaaatgatcg gtcagggtgt atgtgtgtga ctggtcattc
     1501 cctgattctt agcgccaact aagggtcagg gagccttttt ttattcagct gtttctatct
     1561 gaatttattg taagtaatct cttatccaag tgcaagcaag aaaatacaaa aaa
//
LOCUS       DASHWW010000164         1595 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.170, whole genome shotgun sequence.
ACCESSION   DASHWW010000164 DASHWW010000000
VERSION     DASHWW010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.170"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            16..354
                     /locus_tag="U2R64_002932"
     CDS             16..354
                     /locus_tag="U2R64_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HEM8919668.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            341..520
                     /locus_tag="U2R64_002933"
     CDS             341..520
                     /locus_tag="U2R64_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919669.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(563..1033)
                     /locus_tag="U2R64_002934"
     CDS             complement(563..1033)
                     /locus_tag="U2R64_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919670.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            1120..>1595
                     /locus_tag="U2R64_002935"
     CDS             1120..>1595
                     /locus_tag="U2R64_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEM8919671.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGG"
BASE COUNT          584 a          209 c          322 g          480 t
ORIGIN      
        1 agggaggaac agctaatgca atatctagaa gcaaaaatcc caattccaga aggctatgta
       61 attatctccc aagtggatta tgaggagtta aaaaaagctg atgatactgg tagatggatg
      121 acgttgccag aagtgctaga acggattaac agaaaatatg attggtttac ttctagagtt
      181 ttaaagaacc caagatatag aaatattatc gatatcgaga aaaacaaaaa tggatttgtc
      241 tattatccag ttgaaggaag agacacatat ctatttttaa gaagtaaaac acttgaattt
      301 ttagaaacaa atttttcgga aatcttaagg aggcaagcgg atgggaaaat ttaatagagc
      361 gctagtgttc agcgcaccgc taatcatcta cgctttagga ctttggggaa gcaggcaagc
      421 gttgatagga acgattgttt acatggtttg gatttttatg gggcttgatg aagctgaagc
      481 tgagtacaga gcgaaaaagc caaccgaggg ggctgactaa aaatgaatag aaaagagaaa
      541 ctagaatgta tattactatt actcagttta attctttcac taatttctct attgggaagt
      601 ttgtattttt gatatcaaca attttgtgga tttgggttct atttagagta aatatcattt
      661 ttgtttggtg attaaggagt ttattaaaat taattttccc tacttcaaat gcaaggtaac
      721 aagatatagc acttttagga ggaatattta gcggtacagc ttcagagtat attctattat
      781 catcgactga tcctccttta gcaattaatt tcttaaatgg agtagctgac catctgcggt
      841 ttaagttagc ggatgaaagt tctaaattaa ctaacatagc tggttctgtt gaatagttag
      901 aaatgattac ttttgtataa atcatatctg cagcgaagta agaagcatta agttcaactt
      961 ctagttgagg gcgcattcct tttattttta tccctgttaa aaacgtactc aatataaaac
     1021 ttattattga catccattga aaaattgtta agtgaaaaaa attcaaaata aacaccacca
     1081 gtttttaact aaattatacc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     1141 aaaaataaag aagctgtgac tacgagctta caagtggcag aaagcttcga gaaaaaacat
     1201 caacatgttt taagagatat tgatgcacta aaaaaagatg tgtccaattt tggacagatg
     1261 tttgtagaag gtaatgaacc agattcatat ggcagaaatc gacgagtttt cttcattagt
     1321 agagatggat ttttcttgct ggctatgggg tttacaggaa agaaagctat ctacttcaaa
     1381 caaaaataca ttgaagcatt caacgaaatg gaagatgtta ttcgcaagaa tactgttcct
     1441 caaacaattg aagatatgat gatctatcaa ttagaagaaa tgaaagatgt taaaaaagat
     1501 gtttccatgc ttaaagatac tatgcgaatt agcggacaac aagagtttga aattaagcaa
     1561 aaaggaaata tgaaagttat gggagttcta ggggg
//
LOCUS       DASHWW010000165         1457 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.171, whole genome shotgun sequence.
ACCESSION   DASHWW010000165 DASHWW010000000
VERSION     DASHWW010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.171"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            108..1040
                     /locus_tag="U2R64_002936"
     CDS             108..1040
                     /locus_tag="U2R64_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEM8919672.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..1457
                     /locus_tag="U2R64_002937"
                     /pseudo
     CDS             1112..1457
                     /locus_tag="U2R64_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          640 a          169 c          227 g          421 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaattggga tgaaaaatac aagccaactg taaaagaaag ttcctatcga acaactcagg
     1381 tttatctatc attaatttca aaatatataa aagatgatgt acttgtaaaa aacgttaata
     1441 gtaatcttat acaagat
//
LOCUS       DASHWW010000166         1451 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.172, whole genome shotgun sequence.
ACCESSION   DASHWW010000166 DASHWW010000000
VERSION     DASHWW010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.172"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            105..1406
                     /locus_tag="U2R64_002938"
     CDS             105..1406
                     /locus_tag="U2R64_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8919673.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          476 a          293 c          264 g          418 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
     1441 ctcactctat c
//
LOCUS       DASHWW010000167         1434 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.173, whole genome shotgun sequence.
ACCESSION   DASHWW010000167 DASHWW010000000
VERSION     DASHWW010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.173"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..106)
                     /locus_tag="U2R64_002939"
     CDS             complement(<1..106)
                     /locus_tag="U2R64_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEM8919674.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLK"
     gene            296..520
                     /locus_tag="U2R64_002940"
     CDS             296..520
                     /locus_tag="U2R64_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919675.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            963..1169
                     /locus_tag="U2R64_002941"
     CDS             963..1169
                     /locus_tag="U2R64_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEM8919676.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            1169..1420
                     /locus_tag="U2R64_002942"
     CDS             1169..1420
                     /locus_tag="U2R64_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919677.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
BASE COUNT          505 a          263 c          274 g          392 t
ORIGIN      
        1 ttttaagcat atttacaatc aaactaatca aagcaatggt aaacatacca aaaccaagaa
       61 tggtttgaat tgtctcatat gcggacaaaa ggcttactcc tttcatagat tttagcactt
      121 acattcataa gcaccaccac ctttccagaa gtcgccaccg tcttcaaact ttactgtctt
      181 gactattata gcatatctaa aatcgaataa aaattctcaa ttttagctgt ttttgctata
      241 attttagcga ggtgatcgtg atggaacaat atattggttt actcgataaa ttagggtgat
      301 caagacacag ccattgcttg tgcgatttac attacgcacg agtcatgaac caatcaattg
      361 tgtagtggcc aatatagaaa tagcggataa attgctgatt ttggaagaag gcaagtatac
      421 tatttcagtg acaggtcact tcaataaacg aaagcaacta gtcattgaat caatgcaaat
      481 tagaaaccct gatcatttta cgcgatcgat gagcatataa aagaagagct gcagtcctaa
      541 atgaggattg tagctctttt tgttttacat agaaacagta aaaatgaaaa ggcctgttta
      601 ggaaggcaca agcgccttct caattgaaag acctttctct cactccaacc gccaccgccg
      661 ttcgagaaga aaggaagtga acgctacgcg ttcactaaga taaagggtct tgcatagcaa
      721 gacaaaatag aaaaaatttc ctctcaccaa aaggttcgct cctgttcgtt atctctttat
      781 tgatttgtca gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa ggacaagggt
      841 aaatggcacg ctgcgcgccc ttgtcttgtc gcttttcgtt gattcattct ggccaacaaa
      901 tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa
      961 tcatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc ccaaactatc
     1021 atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc aaaagctatt
     1081 gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc gattatattt
     1141 taattgatga gaaaggaaag aaacgctgat gaaaacacaa cacaaattat tgactgtaaa
     1201 agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag cagaagtttt
     1261 acttattccg cggtactgga cgatagaaac ccctttagta gaggatgcac cgactatgct
     1321 atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa acttggaaac
     1381 ttatgaaaac gaatattggt taaccaaatt agagaactaa aaaggagaaa aaaa
//
LOCUS       DASHWW010000168         1424 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.174, whole genome shotgun sequence.
ACCESSION   DASHWW010000168 DASHWW010000000
VERSION     DASHWW010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.174"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(150..1337)
                     /locus_tag="U2R64_002943"
     CDS             complement(150..1337)
                     /locus_tag="U2R64_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HEM8919678.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DASHWW010000169         1422 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.175, whole genome shotgun sequence.
ACCESSION   DASHWW010000169 DASHWW010000000
VERSION     DASHWW010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.175"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..106
                     /locus_tag="U2R64_002944"
     CDS             <1..106
                     /locus_tag="U2R64_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8919679.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(359..508)
                     /locus_tag="U2R64_002945"
     CDS             complement(359..508)
                     /locus_tag="U2R64_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919680.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            970..1182
                     /locus_tag="U2R64_002946"
     CDS             970..1182
                     /locus_tag="U2R64_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919681.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          523 a          213 c          237 g          449 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaattctgtg atattagcgc acctgctgaa ttggtttctt aaacagtatt tttgagaatt
     1201 cgcaagaact cccttataat ataaataaag acagaaggga gcgagaagat atgccaaaaa
     1261 gaaaaagttc agggaaaatg ggaattattc ttgcagtgat ctctgcaatt cctgctattt
     1321 tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta agcacacatt atgagcgtca
     1381 aacaaaaaac gcatatacct gcggtggcag gttatgcgtt tt
//
LOCUS       DASHWW010000170         1404 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.176, whole genome shotgun sequence.
ACCESSION   DASHWW010000170 DASHWW010000000
VERSION     DASHWW010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.176"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            90..1382
                     /locus_tag="U2R64_002947"
     CDS             90..1382
                     /locus_tag="U2R64_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8919682.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          458 a          284 c          255 g          407 t
ORIGIN      
        1 atctttttta ttttccaaaa catatagaaa agacaccttg aaatccttta gaattaattt
       61 ggcgaaccaa cccaaaagga ggaatcaaga tgtcttacac tcaccttatc aaagaaacat
      121 tagatattct agacttatca gttactttta acgaaaattg tctcacaaaa gaaaaataca
      181 aagggcaaat ctgtcatatt tatcgtggaa acttgattta tacagcccaa gaatgcatcc
      241 actgtaaaca ccagattgct tcagatattg tgcgttgggg tacaacaacc gtccggttgt
      301 taatgaacga tgtttctgaa taccgtacct acctcgaatt gaaaaagcaa cgcttcaaat
      361 gcaaagcttg tcagcggacc tttgtcgcag atacttctgt tgcgaaaaaa cattgtttca
      421 tcagtgagaa agtccgctgg tctgtcgtga ctcgtctgaa aaaaaatacc tcaatgacag
      481 agatcgccgc tcagaaaaat ctatcggtct cttctgttta ccgtattatg aagcgatttt
      541 atcgtccgtt gaatcctttt cggacaccgt tacctaaggt actttgtttt gatgaattca
      601 aatcagttcg gggtgtttca ggtgctatga gtttcatcat gatggatgga caaacacagc
      661 gcttattgga cattgtcgag aaccgacaac tgcctttttt aaaacgttat tttagtcatt
      721 tttcacgaga aattcgtgaa gcggtcgaat ggatcgtgat tgatatgtac gctccttatg
      781 tatcgctcgt taaaaagctg tttccaaaag cacagctgat tattgaccgg tttcacatcg
      841 tccaacatat tggtcgtacc tttcgcaatc atcgaatcaa agaaacgaac caactattaa
      901 aaagcaaaga acaaaaacac tatcaattag gtaagcaatt aaaaagatac tggaaacttc
      961 ttcaaaaaga tgaacgcaag cttgattata ctcgacgcct ttggcgacct ggcttcaaag
     1021 ctcatttaac agagaccgat attgtggatc gcttactgaa agggagccct gctttgcgtg
     1081 taggctatca gttatatcaa gactttcttt acgctgtaaa ggaacgagac tacgtatcgt
     1141 ttgaagaact acttaccaat aatatcatgc ttcccgaagg ctatcagacg accttgagaa
     1201 cgttccagaa atttctgcca caaatcaaaa atgctttaca acaaagttat tcaaatggcc
     1261 cacttgaatg tctgaacaac catatcaaag tgttaaaacg aaatgcatat ggctttcgta
     1321 gcttttataa tttcaaattg cgcatcatga ttcgtcatgg caacgcattg attttcaact
     1381 aaaaaagatc aagaggaact gatc
//
LOCUS       DASHWW010000171         1396 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.177, whole genome shotgun sequence.
ACCESSION   DASHWW010000171 DASHWW010000000
VERSION     DASHWW010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.177"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            33..1367
                     /locus_tag="U2R64_002948"
     CDS             33..1367
                     /locus_tag="U2R64_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919683.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT          493 a          200 c          250 g          453 t
ORIGIN      
        1 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
       61 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      121 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      181 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      241 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      301 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      361 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      421 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      481 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      541 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      601 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      661 aaacaccgat aagcttgctc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      721 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
      781 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
      841 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
      901 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
      961 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1021 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1081 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1141 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1201 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1261 attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg aaagattctc
     1321 gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa agtagtaata
     1381 ttgagtggat taatta
//
LOCUS       DASHWW010000172         1368 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.179, whole genome shotgun sequence.
ACCESSION   DASHWW010000172 DASHWW010000000
VERSION     DASHWW010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.179"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            82..>1368
                     /locus_tag="U2R64_002949"
     CDS             82..>1368
                     /locus_tag="U2R64_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HEM8919684.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DASHWW010000173         1305 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.180, whole genome shotgun sequence.
ACCESSION   DASHWW010000173 DASHWW010000000
VERSION     DASHWW010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.180"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>1305
                     /locus_tag="U2R64_002950"
                     /note="aph(2'')-Ia"
     CDS             <1..>1305
                     /locus_tag="U2R64_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HEM8919685.1"
                     /translation="SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHY
                     PKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIR
                     AYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDS
                     IEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEY
                     SYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISEC
                     TIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCN
                     HLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEK
                     AKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYK"
BASE COUNT          552 a          101 c          223 g          429 t
ORIGIN      
        1 aatcattaaa aaaacattat acagagcctt gggaagatga agtttttaga gtaattattg
       61 aatataacaa tgttcctatt ggatatggac aaatatataa aatgtatgat gagttatata
      121 ctgattatca ttatccaaaa actgatgaga tagtctatgg tatggatcaa tttataggag
      181 agccaaatta ttggagtaaa ggaattggta caagatatat taaattgatt tttgaatttt
      241 tgaaaaaaga aagaaatgct aatgcagtta ttttagaccc tcataaaaat aatccaagag
      301 caataagggc ataccaaaaa tctggtttta gaattattga agatttgcca gaacatgaat
      361 tacacgaggg caaaaaagaa gattgttatt taatggaata tagatatgat gataatgcca
      421 caaatgttaa ggcaatgaaa tatttaattg agcattactt tgataatttc aaagtagata
      481 gtattgaaat aatcggtagt ggttatgata gtgtggcata tttagttaat aatgaataca
      541 tttttaaaac aaaatttagt actaataaga aaaaaggtta tgcaaaagaa aaagcaatat
      601 ataatttttt aaatacaaat ttagaaacta atgtaaaaat tcctaatatt gaatattcgt
      661 atattagtga tgaattatct atactaggtt ataaagaaat taaaggaact tttttaacac
      721 cagaaattta ttctactatg tcagaagaag aacaaaattt gttaaaacga gatattgcca
      781 gttttttaag acaaatgcac ggtttagatt atacagatat tagtgaatgt actattgata
      841 ataaacaaaa tgtattagaa gagtatatat tgttgcgtga aactatttat aatgatttaa
      901 ctgatataga aaaagattat atagaaagtt ttatggaaag actaaatgca acaacagttt
      961 ttgagggtaa aaagtgttta tgccataatg attttagttg taatcatcta ttgttagatg
     1021 gcaataatag attaactgga ataattgatt ttggagattc tggaattata gatgaatatt
     1081 gtgattttat atacttactt gaagatagtg aagaagaaat aggaacaaat tttggagaag
     1141 atatattaag aatgtatgga aatatagata ttgagaaagc aaaagaatat caagatatag
     1201 ttgaagaata ttatcctatt gaaactattg tttatggaat taaaaatatt aaacaggaat
     1261 ttatcgaaaa tggtagaaaa gaaatttata aaaggactta taaag
//
LOCUS       DASHWW010000174         1297 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.181, whole genome shotgun sequence.
ACCESSION   DASHWW010000174 DASHWW010000000
VERSION     DASHWW010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.181"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            141..398
                     /locus_tag="U2R64_002951"
     CDS             141..398
                     /locus_tag="U2R64_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919686.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="U2R64_002952"
     CDS             complement(630..1061)
                     /locus_tag="U2R64_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEM8919687.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          490 a          165 c          162 g          480 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta aaatataagc
     1201 tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac atgtttatag
     1261 aatctaaata ataaattttt atgtaccgcc cctcaaa
//
LOCUS       DASHWW010000175         1282 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.182, whole genome shotgun sequence.
ACCESSION   DASHWW010000175 DASHWW010000000
VERSION     DASHWW010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.182"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            81..1253
                     /locus_tag="U2R64_002953"
     CDS             81..1253
                     /locus_tag="U2R64_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HEM8919688.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          478 a          235 c          227 g          342 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     1021 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
     1081 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
     1141 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
     1201 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
     1261 aaaaacattg tatagcattt ta
//
LOCUS       DASHWW010000176         1264 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.183, whole genome shotgun sequence.
ACCESSION   DASHWW010000176 DASHWW010000000
VERSION     DASHWW010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.183"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            82..>1264
                     /locus_tag="U2R64_002954"
     CDS             82..>1264
                     /locus_tag="U2R64_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HEM8919689.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KI"
BASE COUNT          420 a          241 c          244 g          359 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atag
//
LOCUS       DASHWW010000177         1245 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.184, whole genome shotgun sequence.
ACCESSION   DASHWW010000177 DASHWW010000000
VERSION     DASHWW010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.184"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            15..>1245
                     /locus_tag="U2R64_002955"
     CDS             15..>1245
                     /locus_tag="U2R64_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8919690.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGF"
BASE COUNT          383 a          248 c          247 g          367 t
ORIGIN      
        1 taggaggatt caagatgtct catactcagc ttatcaaaga taccctaaat attctagacc
       61 taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa atacaaaggg caaatttgct
      121 tgatttacaa aggaactctt ctgtacaagc cagaagagtg ttcccattgt ctttgtgtcg
      181 tcccctctag gatcattcgt tgggggacga caaccgttcg gttgttactg aatgatgtgt
      241 ctgagtatcg cacttatctg gagctgaaga aacaacgatt taaatgtaag tcttgccaaa
      301 gaacattcgt agcggatacc tctgttgctg aaaaacactg tttcattagt caaaaagttc
      361 gttggtctgt cattgctcgc ttaaaagaga atacttccat gacggaaatc gctcgtcaga
      421 aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg attctaccgc ccattgaatc
      481 ctttcaaaca gactttgcca aaggtcttat gctttgatga attcaaatcg gttcgaagtg
      541 ttgccagtgc aatgagtttt atcatgatgg acggacaaag ccatgcatta ttggatattg
      601 tcgaaaatcg acgcttgcct tatttagaac gctatttttc tcggttttca ttagcgactc
      661 gtgaagccgt tcaattgatt gttattgata tgtatgcgcc ttatgtttcg ttggtgaaaa
      721 agcttttccc gaatgctcag ttgatcatcg atcgtttcca catcgtccaa catattggca
      781 gaactttctt gaatcatcga gtgaaagaaa ccacggtacg acttaaagga aattcccact
      841 ctcaacgagg gttagggaaa aaattgaagc gctattggaa actcctacaa aaagaagaag
      901 caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt taaagattat ttgactgaaa
      961 gtgagattgc cgatcgactg ttagctgctt gtcccaactt acgccaaggc tatcagttat
     1021 accaagacat tctttatgcg gtaaagaaaa gagatcagtc actatttgag gattgtttaa
     1081 ctagagacat tagcggtctg ccagaaacct atacaaccac tttacgaacg tttaaaaagt
     1141 ttctgccaca gatccaaaat gcgcttcact acagctattc aaacggacca ttggaatgct
     1201 taaacaacca catcaaagta ttaaaacgca atgcgtacgg ctttc
//
LOCUS       DASHWW010000178         1231 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.185, whole genome shotgun sequence.
ACCESSION   DASHWW010000178 DASHWW010000000
VERSION     DASHWW010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.185"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>1231
                     /locus_tag="U2R64_002956"
     rRNA            <1..>1231
                     /locus_tag="U2R64_002956"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          323 a          280 c          375 g          253 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc c
//
LOCUS       DASHWW010000179         1193 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.186, whole genome shotgun sequence.
ACCESSION   DASHWW010000179 DASHWW010000000
VERSION     DASHWW010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.186"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1076
                     /locus_tag="U2R64_002957"
     CDS             <1..1076
                     /locus_tag="U2R64_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEM8919691.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DASHWW010000180         1173 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.187, whole genome shotgun sequence.
ACCESSION   DASHWW010000180 DASHWW010000000
VERSION     DASHWW010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.187"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            31..291
                     /locus_tag="U2R64_002958"
     CDS             31..291
                     /locus_tag="U2R64_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919692.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(653..892)
                     /locus_tag="U2R64_002959"
     CDS             complement(653..892)
                     /locus_tag="U2R64_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919693.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT          416 a          164 c          218 g          375 t
ORIGIN      
        1 taatggaaaa acattaagga tggatgaaat atgaataacg aaactatcat tttaggaaaa
       61 aaatatattt gccaacctat tggcttgaaa caaaaagtgg ttggagaagt aatcagtaaa
      121 ttagaaaatt gtgttgtgat ctgcgtagac gaatatcatg acgtcgatcg caatgaaata
      181 ttagaaaaat gcggaaaagt agtggcaaaa tatactcacg tttatgagtt ggaaacaaca
      241 gaatatctat ataactatag caacaaatat gaacatactt tagtttcata aagatttaaa
      301 taaagtgcct tcaaaagcga gaagaccaag cttttgaagg cactttattt agttggcagt
      361 gattgttcat gatttttgat ttattcaaaa ggttcgccta gagaatctgt ctctgtaacg
      421 aggcctggtg gagaaactcg ataaaaacct atactgccag aactgtccta ttttcggata
      481 gacaaactag tagttttaaa aagatcatcc gatccaatca tttcaaaaaa tgcaaaactg
      541 atatcaggat catttagctc aggcttgtta tcgtaaagca tttgtaaagg ttgcatttag
      601 ttaggagtaa acgcgaaact atcatcatta tttgctgaag aagatgaaga agctaattca
      661 gagtttgttt gaaataaagg agacgtgctg acagtttctt taccctgttt tttgcagagg
      721 tagaaacttt tatatcggaa gtttctaccg gagaattttt ctcatttgta gaaattgttg
      781 aatcgatact attcgaaatt tgcgtatctg aaggtatgtt ctttgatgca gaagtcccac
      841 aagcagtaag taacaataaa tttgataaac tgataaacag aattcttttc attatgtaca
      901 cactccttat agtatcgttt agcatacacc tatgctcagt attaggcaaa atcaatgcaa
      961 aactatcaag tcttttatag tatctattag tcttagtaat acatatatgg agagggtgat
     1021 atcccagttc aaaccagata cattggttac catctgtatt aacgattatg cctctaaacg
     1081 ctttttttat gaaaaaattt ataagtgaaa acgtaggtat gatattatct agaggtaatt
     1141 tttttgggta tttaaatagt tgctaggagg ata
//
LOCUS       DASHWW010000181         1146 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.188, whole genome shotgun sequence.
ACCESSION   DASHWW010000181 DASHWW010000000
VERSION     DASHWW010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.188"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            58..339
                     /locus_tag="U2R64_002960"
                     /pseudo
     CDS             58..339
                     /locus_tag="U2R64_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            682..938
                     /locus_tag="U2R64_002961"
                     /pseudo
     CDS             682..938
                     /locus_tag="U2R64_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
BASE COUNT          399 a          176 c          207 g          364 t
ORIGIN      
        1 gatttaccaa catgtttaga cattttcctc taggaaaaaa ttaactagca ccacgggtat
       61 aaacgtaatc ccttcgtatc tgaatatgtt aaacgacttg caaaaggtat ttgtcaactt
      121 tgccaagaaa aagggccatt tataaaagac ggtgtacctt atttacattg tcatcatata
      181 gaatatttgt cgcaaggtgg aaaagatgtg attgaaaact gtatcgcgtt atgtcccaat
      241 tgtcatgcta gaattcatga acttgagtta cctgacgata aagaaaaatt gctgaagatc
      301 gttgaaaaaa gagaaaatag cttttctaaa ataccgtaat ttatttttat aggacaaata
      361 agctaatgtg agctatgcct tctatataag actaagttct attataagta acgaagtaat
      421 tctcgttcct tcctgtagta atatttttta aataacctat aggcttcttc aaaagtacat
      481 cctccagtaa attctaagta ctggaggatt ctttttctag tgttgcttta ctcatgaaaa
      541 agtagttggc tacttcatca aaatttctga acttttttaa tgtataataa agagctcgat
      601 catttactac aaggatgcta gctcctacat tttcacagtt ttttagcaag taaatttttc
      661 taaaatcaca tcaggaaatg catgagattc tttaagaaag gcaattatag ggctatgatt
      721 acggttcgtg taagtgacgc caaaaaagaa tggctttctt atatggctga attttatggg
      781 attactttat ctgaacttct aaaaaactat tcgatggaac aactagaaga tgaatacaat
      841 cgtcaaacgg ctgaaattgc ccataaacat tggataagaa gtgggaaaac aacagtattc
      901 atggaagaat ccttaatgaa tttggtgggc tggaatgacc tgccgtttaa aattcacgcc
      961 cgaaattcag aagcagctct gattggcaaa tacgtgtatt ggtagagata gaagataatc
     1021 aattcgttgt taccgctatt caagtagggc accgaagaaa tgtctatgat taagagactg
     1081 tttattttta caaaaaaata ataactggaa tctagttaaa actcttgaag tgagagattt
     1141 gactag
//
LOCUS       DASHWW010000182         1074 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.190, whole genome shotgun sequence.
ACCESSION   DASHWW010000182 DASHWW010000000
VERSION     DASHWW010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.190"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>1074
                     /locus_tag="U2R64_002962"
     rRNA            <1..>1074
                     /locus_tag="U2R64_002962"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          328 a          213 c          314 g          219 t
ORIGIN      
        1 cggtggatgc cttggcacta ggagccgatg aaggacggga ctaacaccga tatgctttgg
       61 ggagctgtac gtaagctatg atccagagat ttccgaatgg gggaacccaa catctttaat
      121 aggatgttac gattgtgtga atacatagca cattcgaggt agacgcagag aactgaaaca
      181 tctaagtacc tgcaggaaga gaaagaaaat tcgattccct gagtagcggc gagcgaaacg
      241 ggaaaagccc aaaccagcaa gcttgcttgt tggggttgta ggactccaat atggtagttc
      301 tttcagatag tcgaatgact tggaaaagtc agtcaaagag ggtaaaaacc ccgtagacga
      361 aatgtggaag acacctagga ggatcctgag tacggcggaa cacgagaaat tccgtcggaa
      421 tccgggagga ccatctccca aggctaaata ctccctagtg accgatagtg aaccagtacc
      481 gtgagggaaa ggtgaaaagc accccggaag gggagtgaaa tagaacctga aaccgtgtgc
      541 ctacaacaag tcaaagcccg ttaatgggtg atggcgtgcc ttttgtagaa tgaaccggcg
      601 agttacgatt gcatgcgagg ttaagttgaa gagacggagc cgcagcgaaa gcgagtctga
      661 atagggcgtt tgagtatgta gtcgtagacc cgaaaccatg tgatctaccc atgtccaggt
      721 tgaaggtgcg gtaaaacgca ctggaggacc gaacccacgt acgttgaaaa gtgcggggat
      781 gaggtgtggg tagcggagaa attccaaacg aacttggaga tagctggttc tctccgaaat
      841 agctttaggg ctagcctcgg aattgagaat gatggaggta gagcactgtt tggactaggg
      901 gcccatctcg ggttaccgaa ttcagataaa ctccgaatgc cattcattca tatccgggag
      961 tcagactgtg agtgataaga tccatagtcg aaagggaaac agcccagacc accagctaag
     1021 gtcccaaaat atatgttaag tggaaaagga tgtggggttg cacagacaac tagg
//
LOCUS       DASHWW010000183         1061 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.191, whole genome shotgun sequence.
ACCESSION   DASHWW010000183 DASHWW010000000
VERSION     DASHWW010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.191"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(36..992)
                     /locus_tag="U2R64_002963"
     CDS             complement(36..992)
                     /locus_tag="U2R64_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919694.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DASHWW010000184         1051 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.192, whole genome shotgun sequence.
ACCESSION   DASHWW010000184 DASHWW010000000
VERSION     DASHWW010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.192"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="U2R64_002964"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="U2R64_002964"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEM8919695.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          377 a          132 c          182 g          360 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt t
//
LOCUS       DASHWW010000185         1023 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.193, whole genome shotgun sequence.
ACCESSION   DASHWW010000185 DASHWW010000000
VERSION     DASHWW010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.193"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..736)
                     /locus_tag="U2R64_002965"
     CDS             complement(<1..736)
                     /locus_tag="U2R64_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919696.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMDQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNE"
     gene            complement(805..999)
                     /locus_tag="U2R64_002966"
     CDS             complement(805..999)
                     /locus_tag="U2R64_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919697.1"
                     /translation="MIFAGVAAVASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGIIL
                     AAASIVVSLFGMFGQTPQGL"
BASE COUNT          275 a          241 c          138 g          369 t
ORIGIN      
        1 tttcgttttt ttctacttct tcactgataa gtggttcaat atattcctga gaatcccctt
       61 cagtccatgt tgactcttca ttagcttcaa ctggatcaac ttctacttcg gccgtctctt
      121 catcctccat tgtttcttca aagggatcta cctccaattg atccatcaca tcgttctctt
      181 cctcaaatat cgatttctga gtcggaatat cagcttgttc gtcaacatag actgtctctt
      241 tttcttttga ctccttcttt ggaaatattg gtcgttccca tggtacttct tcatttactt
      301 cgacttcact cacttgattc acttttcttt ggtcgctctc taactcttct tctaaaactt
      361 gtaaaagttt ttcgtttcga taagactctt ccacactcat agtttcatcc gtttctttaa
      421 acacatcaag gcggattaaa tccatcaatg taggataaaa accttctgaa atttgataat
      481 ccagtgggcc aaaaacgtat tctgtgccag ccttttctat ttttccttct ttatcatgta
      541 acgtgagagt caatttaaca gaagattgat tctcttgttc taacacttgt cctaacacat
      601 gtagctgttc ttccgtttca atgacagaat atttaattgt tttcggtaaa aaggaagtac
      661 gctttcccac tttcttcgtt gcttttctta ttaactcttt atccaatttt gcattgcctg
      721 aaatcgtaaa aaacatgaat attctccttt cataaaaaaa ggagtaaaaa gtagctatgt
      781 actttttact ccttcatttt gtttttataa tccctgtggg gtttgtccaa acattccaaa
      841 taacgaaacc acaatagaag cggcagctaa aataattcct acccccatca atacatatcc
      901 cacatgcatc ttcccgtttt cagcacctct tcgtccaaat aagaagaaaa gccccccaat
      961 aacaatggaa gcaacggccg caacgccggc aaaaatcatt aaattgtttt ttaagctagt
     1021 tgc
//
LOCUS       DASHWW010000186         1006 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.194, whole genome shotgun sequence.
ACCESSION   DASHWW010000186 DASHWW010000000
VERSION     DASHWW010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.194"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            35..532
                     /locus_tag="U2R64_002967"
     CDS             35..532
                     /locus_tag="U2R64_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8919698.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(569..994)
                     /locus_tag="U2R64_002968"
     CDS             complement(569..994)
                     /locus_tag="U2R64_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919699.1"
                     /translation="MDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFK
                     QYEAQFLPILDQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGH
                     YLEHFRFHFDDLFALLKANGVTELAIYQKGKRIMVPLPV"
BASE COUNT          361 a          167 c          177 g          301 t
ORIGIN      
        1 atttatagta tactatgtca aaaggaggag ttagatgaac aatcaaatca cactagcgta
       61 tttagattat gatgatctag atgctttaca agttgtaagt gttgtcagtt tttatgaatc
      121 gtttatcgat ggcgcagatc cacttgatat gcaaggatat ttacagacac aattgacaac
      181 tgaaatattg gcagtagaat tggcacagtc aaccagtaaa tttattggta ttaaggatca
      241 tcaaatactc attggttata tgaaagtcaa tgatgaaaaa gatgctatag agattcaacg
      301 gctctatctg ctcaaagatt atcaaaacaa agggttaggg caacggttac tcgatgaagc
      361 gaatcgttat gctaaaacga aacaaaaacg ttatttacgt ttgactgttt atgaaaaaaa
      421 tcatgcaggt attcgttttt atgaacgtca tggatttaaa aaaatcggga tcaaacattt
      481 tcctttagga aaacaagatc gtatttgtcc gattttagaa aaagaaatct aaaaaaacgt
      541 cctcactttt gatgctgagg acgttttttt agactggtaa tggaaccata attcgctttc
      601 ctttttgata aatcgctaat tccgtcacac catttgcttt taacagagca aaaagatcat
      661 cgaaatggaa acggaaatgt tcaaggtaat gcccatctga tccaacacta aacaaggtac
      721 caccacgtga aagatataaa tcgatgacat attcatataa cgctaaattg tcatacaagt
      781 aagcgctctt agcatttaat tcgaatgcca atttattttt gattacttga tctagaatcg
      841 gtaaaaactg cgcttcatat tgtttaaatt cagcaacgga tagaccaaat acccgaaaac
      901 catagtcaaa atgagcaaag acatctgctt ctataacaac tagtgcttct gaaagttgtg
      961 caaaatactg aggaatcaca atagcaggat ccatatcttt gacttc
//
LOCUS       DASHWW010000187         1001 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.195, whole genome shotgun sequence.
ACCESSION   DASHWW010000187 DASHWW010000000
VERSION     DASHWW010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.195"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            51..306
                     /locus_tag="U2R64_002969"
                     /pseudo
     CDS             51..306
                     /locus_tag="U2R64_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            370..1001
                     /locus_tag="U2R64_002970"
                     /pseudo
     CDS             370..1001
                     /locus_tag="U2R64_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          344 a          181 c          183 g          293 t
ORIGIN      
        1 ttcaaagtta gtagagaaaa tgtagttata tatttaaatt tttaccagaa agaaatgaac
       61 accttcaatt atctaaatct cgaaaatggt tagatgtaat catcaggaaa aacaatctta
      121 aacgaattac tattcatggt cttagacaca cacatgctag cttgctttta gcaagctagt
      181 gcaaatatta aagatgtgca agagcgttta ggccactctt ctattcaaat cattatggat
      241 ctatatattc atattacaga caaaagaaaa gaagaaaccg tagcgcaatt cgcaaaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DASHWW010000188          982 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.196, whole genome shotgun sequence.
ACCESSION   DASHWW010000188 DASHWW010000000
VERSION     DASHWW010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.196"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..206
                     /locus_tag="U2R64_002971"
     CDS             <1..206
                     /locus_tag="U2R64_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919700.1"
                     /translation="LGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDN
                     LIDISYYGPGKKYIAEMEAEFDE"
     gene            199..870
                     /locus_tag="U2R64_002972"
     CDS             199..870
                     /locus_tag="U2R64_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEM8919701.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
BASE COUNT          359 a          152 c          202 g          269 t
ORIGIN      
        1 atttaggcaa ccatgtaact atttgggatc atgtttatct tatccatcta tcgaagcatt
       61 cgaataaacc tgaatatatt tacgtcatcg aagatggctt gattgatgcg ctagaagagt
      121 acgacagaga taacttgatt gatatctctt attacggacc aggtaagaaa tacattgctg
      181 aaatggaggc agaatttgat gagtgaaatc aaagggacaa cgaactttga aaaacttttt
      241 agtcgtaagt taaataaaat tctcaagaaa aaaggaaatt ttgattattt atcttgggct
      301 cacgcgtggg agattatgaa aaagaatgat ccacaggcaa cggtaactat taatgagtac
      361 aaacactaca gggttgtttc tggaactcat caagactttc ttgttgagga atataaacct
      421 tttcttatgg atgaaactgg gacttatgta tctgtctcag taacggttaa aggacacacg
      481 gaaaccgaat tatttcctgt tttagattat cgaaaccaac cagttgttaa accaaatgca
      541 atgcaaatca ataactcatt gaagcgatgc tttgtgaaag cattggctct acacggactg
      601 ggattatatg tatttcaagg ggaagatatt ccaacaccac ctagaatcga tacaaagaaa
      661 ttaaacatgc tagagacgat tctagaagct ttcaatgagc agatgggtaa agatatgacc
      721 aaaaccttaa tcgaatatgt taatgagcag acagataaat tagggctctt agctgataac
      781 gttgaaacta ttgaacagtt aagctatgag caatgtgcct tgatggagcg agcaatagca
      841 gctaagagaa aagaattaga taagaagtga tatgagtgtt taaaccatta atcgattcat
      901 attcagcggt tctgaaaaag ttcaaaggaa aagacataag cgcaaccatc aatgaggaag
      961 tgaacattga tcgactaaag ac
//
LOCUS       DASHWW010000189          973 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.197, whole genome shotgun sequence.
ACCESSION   DASHWW010000189 DASHWW010000000
VERSION     DASHWW010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.197"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            42..>973
                     /locus_tag="U2R64_002973"
     CDS             42..>973
                     /locus_tag="U2R64_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8919702.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVT"
BASE COUNT          348 a          177 c          186 g          262 t
ORIGIN      
        1 caaaatagtt ccgacgaaag aattataagg agtgagtaca aatgacctat aaccatctta
       61 caccaactga actcgtaatg atagaagctt atttcaatca atcacaacct gtttcaaaag
      121 tagccaatct gttacaacgt tctcgacaaa ctatttataa ggtctatcgt tttcttaaat
      181 ctggtggaag cgcaatgagc tactataaac aatataagaa aaacaaacgt aactgcggaa
      241 gacatccgat tgttttacct gatgagcaac aggaatacat tcaaaaaaag gttgttcaag
      301 ggtgggctcc tgatgtcctt attggtcgag cagagtttcc tattgcttgt tcggtacgca
      361 cactgtatcg aatgtttaaa gataaaacct ttgacactca cgatttacca atgaagggaa
      421 aaagaaaacc aaacggtcat aaagaaaaaa gaggaaaaca agggtttcgc cggtcaatcc
      481 gagacagaaa gacagactat acccagtttg atcatgaatt tggtcacctg gaaggtgaca
      541 ctatcgtggg tggaaaacat aaaagcgcgg tcatcacatt agttgaacgg ctatctaaag
      601 tcatcattac cttgaaaccc gaaggcagac aggctaaaga cattgaaaat aggctgaatc
      661 aatggtttcg ttgtgtccca aaaaacttat ttaaatccat cacatttgat tgtggaaaag
      721 aattctcaaa ttggaaaaag attagtaata ccaacgatat ttcaatttat tttgcggatc
      781 caggaacacc ttctcaacga ggattgaatg aacattcaaa tggcttatta cgtaaagatg
      841 gtttgtataa agctatggat tttaatggtg tatctgaaac ctttatccaa tcggtggcat
      901 cgaaacgaaa tcatattcct agaaaatcat tacactatcg gacaccaatg gaagtatttt
      961 tgagttacgt cac
//
LOCUS       DASHWW010000190          943 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.199, whole genome shotgun sequence.
ACCESSION   DASHWW010000190 DASHWW010000000
VERSION     DASHWW010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.199"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..258
                     /locus_tag="U2R64_002974"
     CDS             <1..258
                     /locus_tag="U2R64_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919703.1"
                     /translation="KGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            260..397
                     /locus_tag="U2R64_002975"
     CDS             260..397
                     /locus_tag="U2R64_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEM8919704.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            434..727
                     /locus_tag="U2R64_002976"
     CDS             434..727
                     /locus_tag="U2R64_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919705.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            724..>943
                     /locus_tag="U2R64_002977"
     CDS             724..>943
                     /locus_tag="U2R64_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEM8919706.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
BASE COUNT          350 a          134 c          201 g          258 t
ORIGIN      
        1 aaagggaatg ctgttgatag cgtagatgaa ttggctaata ttaaggcatt atacgaaacg
       61 ctgaaggcag aaaatgatga attgaaacag ctaaattcta aagcaatgct aaacaatgta
      121 gcaatcaagc aagaaaatgt cttattgaaa gaaaagtcag aaagtttagc gcagttgaat
      181 tcaaaaacga tgcttgcttc tgtacaaaat accaaggaaa tcgaagaaat caaaaaacaa
      241 ttacaaggtg ggaagtaaca tgtattcata tgaagatatc aaactaatgt atgactgggg
      301 ctgtttcact aacgaacaag taatggtttt cgttccatta tgcattacag acgaagaagc
      361 agataaaatc attaataaag ataagagcgc atcttaattg atgcgttttt atttaaggta
      421 aaggagttgt cacatgatta atttagggga atggggaatg atagcaggat caataaccgc
      481 tatcgtttct ttgattttat tagtaattag accgattgct gcatctttct cgaaaattac
      541 tgagactctt tcaaaagtaa gccacaattt agatttgctg actaaagatt tagaatcgag
      601 caaatcagat cgattgatga ttcatgaaga actaaagaaa cacgatgaaa gattagatac
      661 acatacagaa aaattggtgg aacacacgca acaaatcaaa actttgttta gggagagaag
      721 aaaatgaata ataaaacgtt cgaagtacta aaatggttcg cactggtaat tattcccgca
      781 ctagctactt tcgtggggtt agttggtaaa gcgctcaatt ggcagtacac agatatctgt
      841 gttgtcatca ttactggttt tggcgcgttt ttagggagtg tgttgggtgt atcaaatcga
      901 acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa aca
//
LOCUS       DASHWW010000191          870 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.200, whole genome shotgun sequence.
ACCESSION   DASHWW010000191 DASHWW010000000
VERSION     DASHWW010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.200"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            39..>870
                     /locus_tag="U2R64_002978"
     CDS             39..>870
                     /locus_tag="U2R64_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8919707.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     V"
BASE COUNT          301 a          151 c          167 g          251 t
ORIGIN      
        1 aatagttccg accaaagaat tataaggagt gagtacaaat gacctatacc catcttacaa
       61 cggatgaact tgtaataata gagtcttatt tcaaaatgaa tcaatctgtt gctaaaactg
      121 cccattgctt gaatcgttca agacaaacga tccataaagt atatctgttc ttcaagcaag
      181 gaaaatcagc cttagaatat tatcaacagt ataagaaaaa caaatcaaac tgtggtagac
      241 gtccgcttgt tttacccgag gaacaatcag aatatattca aagaaaggtt gttcaaggat
      301 ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat tagttgttct gctcgtacca
      361 tttatcgtat gttcaaaaag gggctatttg attcttctga cttaccgatg aaaggcaagc
      421 gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac tttccgccgc tctattcatg
      481 aacgtgaaaa ggattatagc caattctcaa atgagtttgg tcaccttgaa ggtgacacta
      541 tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt tgaacgatta tcaaaagtta
      601 tcatcacatt gaaaccgtgt ggtagacaag cgattgatat tgaaaaaaaa ttaaatcaat
      661 ggtttgaatc tgtaccgaaa aacctattca aatccatcac ttttgattgt ggaaaggaat
      721 tttcaaattg gaaacagatc agtaatgtca atgatattgc catttatttc gctgatccag
      781 gaacgccgtc tcaaagaggc ctaaacgaga attctaacgg attgttacgt agagatggtt
      841 tattgaaatc tatggatttc aattcagtag
//
LOCUS       DASHWW010000192          791 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.202, whole genome shotgun sequence.
ACCESSION   DASHWW010000192 DASHWW010000000
VERSION     DASHWW010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.202"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..782
                     /locus_tag="U2R64_002979"
     CDS             <1..782
                     /locus_tag="U2R64_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8919708.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DASHWW010000193          783 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.203, whole genome shotgun sequence.
ACCESSION   DASHWW010000193 DASHWW010000000
VERSION     DASHWW010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.203"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            17..>783
                     /locus_tag="U2R64_002980"
     CDS             17..>783
                     /locus_tag="U2R64_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HEM8919709.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSR"
BASE COUNT          280 a          145 c          135 g          223 t
ORIGIN      
        1 aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc tagtcactaa
       61 aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg
      121 gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg
      181 taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt
      241 ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag
      301 aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc
      361 tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc
      421 caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag ccttaaatga
      481 taagtatgtc gctattttta tggacgctac ttacattcca ctaaaacgtc aaaccgtatc
      541 caaagaagcg atttatattg ccattggtat acgagaagac ggcactaaag aagtactgag
      601 ttatgcgatt gctccaactg aatcaacata cgtttggaat gagctgctac aggatattaa
      661 ctccagagga gttcaagaag tcttgctttt tattacggac ggcttaaaag gcatgaaaga
      721 tactatccat caaatttatc ctaaagcaaa atatcagcat tgttgtatcc atgtatctcg
      781 taa
//
LOCUS       DASHWW010000194          783 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.204, whole genome shotgun sequence.
ACCESSION   DASHWW010000194 DASHWW010000000
VERSION     DASHWW010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.204"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            281..>783
                     /locus_tag="U2R64_002981"
     CDS             281..>783
                     /locus_tag="U2R64_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HEM8919710.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKT"
BASE COUNT          299 a          121 c          115 g          248 t
ORIGIN      
        1 caaactgttt tcttgactag ggcaatttac gatttaaaag taaataaaac attaataaga
       61 taaaaattaa tcgatttcat ttttatttcc ataattttca taggtgtttt taaaagttac
      121 acaaaaaata gaataacaaa aaaattaaca ttgaattaat aatagttata cccgtggtgc
      181 tagttaattt tttcctagag gaaaatgtct aaacatgttg gtaaatcaac aaaaaaacgc
      241 atatagtagt ctcaaaactc ccaagaaatg aggactacat atgcgttcat caaaatatac
      301 tgaacattat acagatactt ttataacatt caaggaaatt atgagaactg tttctaacat
      361 ataccacaat tgtgtaccag ataagattaa aaatcgaaga aatactgatc aactgaagca
      421 acgcgataca gtgattattg cttgtgttat atggggcata attaatggct atactagcca
      481 aagagccacg tatagagcgg tttgttccgt cttatttcct aatggtgact ttcctagtag
      541 gagtcgattc actcgcttaa gttcaaactt agcttacact atcaagatta ttcgatactt
      601 ttttatcaag aagctcacca aaggtgaact agtcggaatt atagatagtt ttcctagtcc
      661 attatgtaaa ccagttagaa atagacaagc aaaactattg aatcaaatag ccaaagttgg
      721 ctataactca acaaaaaaat cttattttta tggtcttaaa attcatatga tcgttactaa
      781 gac
//
LOCUS       DASHWW010000195          763 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.205, whole genome shotgun sequence.
ACCESSION   DASHWW010000195 DASHWW010000000
VERSION     DASHWW010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.205"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(237..716)
                     /locus_tag="U2R64_002982"
     CDS             complement(237..716)
                     /locus_tag="U2R64_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919711.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          261 a          101 c           85 g          316 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact tggcagtata
      541 tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa aatctaaact attaaaaaca
      601 tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg aacaatagat
      661 cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata gcacatatta
      721 agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DASHWW010000196          755 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.206, whole genome shotgun sequence.
ACCESSION   DASHWW010000196 DASHWW010000000
VERSION     DASHWW010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.206"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..104
                     /locus_tag="U2R64_002983"
     CDS             <1..104
                     /locus_tag="U2R64_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HEM8919712.1"
                     /translation="ETVEFPIEEGALIIATVDDPKQNVFTLEKVGVI"
     gene            104..721
                     /locus_tag="U2R64_002984"
     CDS             104..721
                     /locus_tag="U2R64_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919713.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
BASE COUNT          283 a           95 c          162 g          215 t
ORIGIN      
        1 ttgaaacagt agaatttcca attgaagaag gagctttgat tattgcaact gttgatgatc
       61 caaaacagaa tgttttcact cttgagaaag ttggggtgat ttgatggtta aagtaaagag
      121 aatgatggag actgatgaat ctggtgttaa acgtcaattt atgccaatta cacatgtttc
      181 tgcagtttta ggcttagaaa aaatgatatc aggacaatca aaagttcttt cggttaatgg
      241 taaatatggt gcagtcattt taacgaaagc tgatttagga ttagagaatg caattactga
      301 actaccttat gcaagcgaga caagcgatgg tattcttact gctgaaatgt ttcaaaagat
      361 cgtaaatgga gaaggtggaa catatatttt gccgattgct actcctgaac aattaggagg
      421 tataaaagtt ggggaactct tagaagttac tgaagaaggt gttttatctg caactaagca
      481 aacagacttc aatttctctg aagaattaaa gggaaaatta gaatctctaa aaatattaaa
      541 agcaggtgca aatatatcaa ttgcagaaga tggaacaatt agttctacag gtggtagtgg
      601 gactggtggt gttaatcagt catatgtaga tcaaaaattc caagaagctg taaatcaagc
      661 agaaaattac acaaacgaaa gaattccaaa ttttactttt gaaaaaatcg gggaggtata
      721 gaaaatgaca gatatcgtaa aaataaaaca aagcg
//
LOCUS       DASHWW010000197          755 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.207, whole genome shotgun sequence.
ACCESSION   DASHWW010000197 DASHWW010000000
VERSION     DASHWW010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.207"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>755
                     /locus_tag="U2R64_002985"
     CDS             <1..>755
                     /locus_tag="U2R64_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8919714.1"
                     /translation="FLDYEKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGE
                     FSQQTLPAYKRTNDSLETTIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVA
                     EDVLAFKERTLEANYSVIFMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAP
                     TESAYIWKEVLQDLRKRGLEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIA
                     HKVRVRGRKEICEDFKLVYQANSKEEALDHIDF"
BASE COUNT          259 a          120 c          151 g          225 t
ORIGIN      
        1 ttttttagat tacgaaaaat atgatcgaaa tggattcaat tcaggaaatt cccgtaacgg
       61 gaattattca cgtacattta aaacagaata tggcgagttg aatttaacta ttcctagaga
      121 tcggaatggc gaattttctc aacaaacact accagcatat aagcgaacca atgattcatt
      181 agaaacgacc attatccaat tatttcaaaa aggcattact atggctgaaa tctccaaatt
      241 aattgaaaaa atgtatggtc accactatac gccacaaaca atctccaaca tgagtaaatt
      301 ggtggctgaa gatgttttag cttttaaaga aagaacgtta gaagccaatt attccgttat
      361 atttatggat gcgacgcata tccctgtgaa gcgacagact gtttcgaagg aagcagtgta
      421 tattacgatt ggtattcgtt tggatggaac caaagaagtt cttgggttta ctattgcccc
      481 aactgagtct gcttatattt ggaaagaagt tcttcaagat cttagaaaac gtgggttaga
      541 agaagtttta ttagtagtga cagacggatt aagctgtatt gaagaaagta tccatagtgt
      601 gtatccgaat gcccaatttc aacaatgttg tgtgcatgta tctagaaata tcgctcataa
      661 agttcgtgtt cgaggtcgaa aagaaatttg tgaggatttc aaattggttt accaagcgaa
      721 ttcaaaagaa gaggcattgg atcacatcga cttta
//
LOCUS       DASHWW010000198          744 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.208, whole genome shotgun sequence.
ACCESSION   DASHWW010000198 DASHWW010000000
VERSION     DASHWW010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.208"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            178..381
                     /locus_tag="U2R64_002986"
     CDS             178..381
                     /locus_tag="U2R64_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HEM8919715.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            381..731
                     /locus_tag="U2R64_002987"
     CDS             381..731
                     /locus_tag="U2R64_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8919716.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          300 a           80 c          120 g          244 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcgtcaatc
       61 attgttatat aataaaatgt tatataataa aattactaat gatatttaat attacaagca
      121 atcttaagaa attcgaaaag gaaaaaatga ttatgaaaaa gaaagaaaaa gaaagtattg
      181 aaacattgtg ttattctagg aatattagga acttgtctag ctggcattgg tacaggaata
      241 gacgttgacg cagctactta ctatggaaat ggtctttatt gtaacaaaga aaaatgttgg
      301 gtaaattggg gacaatcatg gtcagaaggg ttaaaacgtt ggggagataa tctttttggt
      361 agttttagtg gaggacgata atgacttcaa taaacattga tcacacaaaa aaagtcatac
      421 atgaattata caatagttta atgacacgac ctaatcagac gaaagcatta ttagatatta
      481 ctgatgtttt atttcaggta tataaaaaaa ttgatacagc aaaatatcct gaaattcttg
      541 taaataaatt agttaattat atttacatcg tgggttttga taataaaata cgctttattg
      601 ataatgatga aaaattatta atagaattag gggatatttc taaaaaagct ggaattaata
      661 gtaaatacaa agcaaacttt acagataaat cgcaatttta tagttattca gaaacaatgc
      721 ctcaacgata aaatatagta tact
//
LOCUS       DASHWW010000199          734 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.209, whole genome shotgun sequence.
ACCESSION   DASHWW010000199 DASHWW010000000
VERSION     DASHWW010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.209"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            219..>734
                     /locus_tag="U2R64_002988"
     CDS             219..>734
                     /locus_tag="U2R64_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8919717.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIE"
BASE COUNT          255 a          114 c          163 g          202 t
ORIGIN      
        1 tttctgaagt acatccgcaa ctgtccatac tctgatgttt tatatctttt ctaaaagttc
       61 gctagataga gttctatatt agagatgtaa agagttttgg tgaagaggtt tgtgagtatg
      121 gcttttataa ccagggtgca atgagaagca ctaacagcag ctagcttaag aacgcatagg
      181 atatactttt tatggaagtc acagaggagg aataaaattt gaacaggatt aacagagtaa
      241 cctctattct tattcagctg caatcaaaaa aaataattcc tgccaaagaa attgcacagc
      301 gatttaatat aagcttaagg acagtttaca gagatatccg gacacttgaa gaagccggaa
      361 taccaattgg atctgaggcc ggaaaaggat attttcttgt agagggcttc ctacttccgc
      421 cggtaatgtt tacagcggcg gaagtgggtg cattgattac agcagggaaa tttttaaatt
      481 gccatggaga tgaatcattt ataaaggatt ttgattcagc tatgtataaa atcaaatcta
      541 ttttgaagca tggtgaaaaa aactatgcac aggagttgga gaacagtatt aacgtgtaca
      601 gcacatctgg acagaaaaat acattggcgg ataacgttat tgcagcaatt cagactgcaa
      661 tctgcaataa aagggtaata tcaattcaat atcctgcatc aggagggcaa gaaccggaaa
      721 gcagaatgat agag
//
LOCUS       DASHWW010000200          731 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.210, whole genome shotgun sequence.
ACCESSION   DASHWW010000200 DASHWW010000000
VERSION     DASHWW010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.210"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="U2R64_002989"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="U2R64_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEM8919718.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..675)
                     /locus_tag="U2R64_002990"
     CDS             complement(481..675)
                     /locus_tag="U2R64_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919719.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          220 a          156 c          122 g          233 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
      661 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
      721 catttgttag t
//
LOCUS       DASHWW010000201          698 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.211, whole genome shotgun sequence.
ACCESSION   DASHWW010000201 DASHWW010000000
VERSION     DASHWW010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.211"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..241)
                     /locus_tag="U2R64_002991"
     CDS             complement(<1..241)
                     /locus_tag="U2R64_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8919720.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYI"
     gene            335..571
                     /locus_tag="U2R64_002992"
                     /pseudo
     CDS             335..571
                     /locus_tag="U2R64_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          222 a          123 c          115 g          238 t
ORIGIN      
        1 caatgtattc tttttcctca gcaggaaaaa tgatttcggt tctcccacaa cgtcgcttat
       61 tttctttgta ttgttcaaag tattcaagtg ctgttccacc acatttgaga aagttataga
      121 cattgtaaat tgtttggcgt ccacgtttaa gctgtttcgc aacgatagca accggagttt
      181 cttgatgaaa atatgcttct atcattacaa gctcgtttgg tgtaagatgg gtataagtca
      241 tttatgttca ctctccttgt atgctttagc gggtattaca attggagtgt aacataaatg
      301 gcttttttat ttgtctcgct taattataca aacggcgtta ttaaaaaatc ttcctgaaac
      361 acttgatgca caacttcgca cgaaacttca aaacctttta acgtatgaag aaggtattta
      421 caatgctatg atttacccgt attctaatgg caaaatagag gccaagattc cccatatcaa
      481 gacactgaaa cgattatctt atggatttaa atcatttgag aacatgaaaa tcaggatttt
      541 tttgatcaat caattgattc aagtgaaata acaaaaaaat ctgagacaga aggtcagtcc
      601 ttctatcggc tctatacttt ttgatgttgg tgaacttcac caacatcttt tttgtataaa
      661 aaaatataga aaagacaccc tgaaatcctt tagaatta
//
LOCUS       DASHWW010000202          687 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.212, whole genome shotgun sequence.
ACCESSION   DASHWW010000202 DASHWW010000000
VERSION     DASHWW010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.212"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            233..687
                     /locus_tag="U2R64_002993"
                     /pseudo
     CDS             233..687
                     /locus_tag="U2R64_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          247 a           80 c          111 g          249 t
ORIGIN      
        1 ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa agaggaagtc
       61 caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata tacatccctg
      121 ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga atgggataaa
      181 atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga tagtgaacat
      241 acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta ctttcaaaag
      301 attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat acaagtttaa
      361 ttttgtttaa tcttcagtat ctactgaaag tatctatttt tcaattcttt ctgagagtag
      421 gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata tatatacgtt
      481 ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg aatatctcaa
      541 ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac catatttgaa
      601 tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta atcaaggaaa
      661 tatgaaggtt ctgttgcgaa gtttgaa
//
LOCUS       DASHWW010000203          670 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.213, whole genome shotgun sequence.
ACCESSION   DASHWW010000203 DASHWW010000000
VERSION     DASHWW010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.213"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..>670)
                     /locus_tag="U2R64_002994"
     rRNA            complement(<1..>670)
                     /locus_tag="U2R64_002994"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          134 a          213 c          147 g          176 t
ORIGIN      
        1 gtttcaacct tgcggtcgta ctccccaggc ggagtgctta atgcgttagc tgcagcactg
       61 aagggcggaa accctccaac acttagcact catcgtttac ggcgtggact accagggtat
      121 ctaatcctgt ttgctcccca cgctttcgag cctcagcgtc agttacagac cagagagccg
      181 ccttcgccac tggtgttcct ccatatatct acgcatttca ccgctacaca tggaattcca
      241 ctctcctctt ctgcactcaa gtctcccagt ttccaatgac cctccccggt tgagccgggg
      301 gctttcacat cagacttaag aaaccgcctg cgctcgcttt acgcccaata aatccggaca
      361 acgcttgcca cctacgtatt accgcggctg ctggcacgta gttagccgtg gctttctggt
      421 tagataccgt caagggatga acagttactc tcatccttgt tcttctctaa caacagagtt
      481 ttacgatccg aaaaccttct tcactcacgc ggcgttgctc ggtcagactt tcgtccattg
      541 ccgaagattc cctactgctg cctcccgtag gagtttgggc cgtgtctcag tcccaatgtg
      601 gccgatcacc ctctcaggtc ggctatgcat cgtggccttg gtgagccgtt acctcaccaa
      661 ctagctaatg
//
LOCUS       DASHWW010000204          628 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.214, whole genome shotgun sequence.
ACCESSION   DASHWW010000204 DASHWW010000000
VERSION     DASHWW010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.214"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          241 a           80 c           79 g          228 t
ORIGIN      
        1 aagaaggtat caagagtcac agtgaattta ttccgaaaag tgaaaagagc aaatataaaa
       61 tttaataaaa atatagaact aaataggaaa acgtagacgt aattttctac gttttccttt
      121 tcatatatat taaatattac ggaaaattat ataaactaat ttagtgtttt gtttgtaatt
      181 cctaattttg ctccactttt agataatttt taggtctatt taactcatca gacattctat
      241 gctcattttc tccaaatttg tttcaactct ttcgtactta attttgcgta tttgaaaatt
      301 cttcttttag agtactttta ttacgatact agtatgatat atatctatag caaacagtta
      361 aaatcttcct aaaataagcg aatagcattc ctaaaaccta taaaattttt agatgaagcg
      421 acaagtggac aattaataaa ctacttgaac atgaaattat ggatcacctt tcaaatttag
      481 aaaatggaat tcttatactt attgcacaac atttattgat tgcaaaatta tgtgacaaaa
      541 agaactagta gaagaaggaa taatggcttg ataataaagt actacctatt aaaggtagta
      601 ctttatttaa tttagtataa attaacat
//
LOCUS       DASHWW010000205          627 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.215, whole genome shotgun sequence.
ACCESSION   DASHWW010000205 DASHWW010000000
VERSION     DASHWW010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.215"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>627
                     /locus_tag="U2R64_002995"
     CDS             <1..>627
                     /locus_tag="U2R64_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEM8919721.1"
                     /translation="KDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPA
                     GYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPIT
                     ADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWK
                     EKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          256 a          101 c          141 g          129 t
ORIGIN      
        1 aaaagatggt tatacagatg cgaaatggcc agaagaagca actcaaccaa ttacagcaga
       61 tgatacagaa tttgtatcaa gtgcaacaaa actggatgat atcattgaaa atccaggaga
      121 aaacattcct gcaggctacc acaaagtaac cttcaccgca ggagaaggaa caagtattga
      181 aagtggaaca acagtctttg cagtgaaaga cggcgtaagc ttaccagaag ataaacttcc
      241 agtgttgaaa gcaaaagatg gttatacaga tgcgaaatgg ccagaggaag caactcaacc
      301 aattacagca gatgatacag aatttgtatc aagtgcaaca aaactggatg ataaatctga
      361 cgctgacaaa tataatcctg aaggtcaaaa agtgactaca gaattgaata aggaaccaga
      421 cgcatttgag ggaattaaga acaaagaaga tttaccaaaa gatactaagt atacttggaa
      481 agaaaaagta gatgttagcg cagctggaaa taaaaaaggg actgttgtag tgacatatcc
      541 agatggatca tctgatgaag ttgaagtaga tgttacagtg acagacaatc gttctgacgc
      601 cgataaatat gagccaacag tagaagg
//
LOCUS       DASHWW010000206          587 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.216, whole genome shotgun sequence.
ACCESSION   DASHWW010000206 DASHWW010000000
VERSION     DASHWW010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.216"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          191 a           83 c           83 g          230 t
ORIGIN      
        1 aattatagag ccattttttc ttgatgtgat atccttgtct tttttgtaat gtttttaact
       61 tattgctttt gcaaaattta tttacctgtt ttctggatca acgatagtgt acattatgct
      121 atccttgttt ggattttagg acgtttaaag aggcactttt ttacataact taatccatag
      181 accttttaag catgctgtga gataataata aagaagagtt taaagcgcac cccaaaccac
      241 ttccccataa gtgtattacg ctttaaactc ttttatattt gaattcacta agaagcatac
      301 catatttttg aaaaaaagtg agaaaaaagg cttataatta ggatttagag taattaatta
      361 gatgtttatt ttataggact gatactatag attacaaata gtatcgtatt tcgcaatctt
      421 aaaattatct tcttactgtg aataagataa taaaatttgt atttgtcctt tttaggtaac
      481 ttattttaat ctatatacct ttctggatca acgaaagtat actttatata gtcataacgc
      541 cgatggtaac tatgcactgt aacgataatg ctgctaaaat atctttt
//
LOCUS       DASHWW010000207          581 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.217, whole genome shotgun sequence.
ACCESSION   DASHWW010000207 DASHWW010000000
VERSION     DASHWW010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.217"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(306..569)
                     /locus_tag="U2R64_002996"
     CDS             complement(306..569)
                     /locus_tag="U2R64_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEM8919722.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          100 c           78 g          179 t
ORIGIN      
        1 tgtatggatt ttttcattta cacaaaatat tttatactct cctgaatttt ttcatgttga
       61 aaacatcact aatcaaaggc aaattataat ttagaaatag aatgaaaaca ctaaatgaaa
      121 atagaacatt agaaaaaata gaatcaaaaa aacccaagac tagtgccgaa ataagggaaa
      181 caatcgaagc tacaaaaaat aatgatttcg ttgaacagga ccaatttatt tgtttccgat
      241 atttctcaaa aagaactttc tttgggaaag ttaaaggcga ctgtaaagtc gcctttagtc
      301 cttttttacc aagctgctgc atatttagct ccatattttt taattaatga tttggctgta
      361 gcaacaatac cagctgtaat taatccgcct ccaacaactg cagcaacaat agaaatgatt
      421 gtagcaaccg tgctaccagt attaattatg tcaataactt ttttagctgc ataagaagaa
      481 attccaatgt tagcacttag cattggtaca ccaacaaaga atcccgcaaa acctaaaatt
      541 ggtaaaacta ataataaatt ctttttcata ataattcctc t
//
LOCUS       DASHWW010000208          578 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.218, whole genome shotgun sequence.
ACCESSION   DASHWW010000208 DASHWW010000000
VERSION     DASHWW010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.218"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            126..413
                     /locus_tag="U2R64_002997"
                     /pseudo
     CDS             126..413
                     /locus_tag="U2R64_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            427..>578
                     /locus_tag="U2R64_002998"
     CDS             427..>578
                     /locus_tag="U2R64_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919723.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWV"
BASE COUNT          200 a           91 c          122 g          165 t
ORIGIN      
        1 cattggtgca gacagatgga gaccaagcca ttgcaggaca taagaatttt tcaggttctg
       61 taacaatcaa taataaacgt gttttgacga ctgatgataa cagatatgaa gtggtaaatc
      121 tggttgtcac taacggtaat acagggacag caaagcttta tcgtgaagga aaaacagttt
      181 ctatatattt tgtggcttta aacggaaaaa gtagtggcgg gaatgattcg gttattttaa
      241 ctgttccaga aggctatcgg acaccaatta gttttgaaca actggttggg tcaatagacc
      301 gttctacttt gaacagtgct caactatcta ttggcgcaga cggagccatt aaatggagaa
      361 gaaattcaag ttatggatca gcttattcat ttgttatcac ttattcaatt taagggagga
      421 aatctaatga aagtagttta caaatcaatc aagccttacg gattcgagca aatcattttg
      481 aacaatcaag aaaatatccc tgaaaactgt acagagatta aaccaccagt tcctaactgg
      541 agaccaagat ttgattttga taaaaaacag tgggttga
//
LOCUS       DASHWW010000209          578 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.219, whole genome shotgun sequence.
ACCESSION   DASHWW010000209 DASHWW010000000
VERSION     DASHWW010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.219"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..300
                     /locus_tag="U2R64_002999"
     CDS             <1..300
                     /locus_tag="U2R64_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8919724.1"
                     /translation="FMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          206 a          101 c           69 g          202 t
ORIGIN      
        1 tttatgacta ggaaatggaa aaagcagtat ccaagagtcg tcaatttact cttgaatcct
       61 gccctattaa ccttttataa tttccctcac gccatcagac gaacaattta ttcgacgaac
      121 ctgattgaag gctttaataa gcagctaaaa cgatatactc gaagaaaaga acaattccct
      181 aatgaagaat ctctagagag attcttcatt tctcaattta atcaatataa ccaaaaattt
      241 ttaggtagaa ttcacaaggg atttaaagaa attcaggata cattagagtc gatgatttaa
      301 ctgtaattaa cagaatggat tttccattta catataattc ttgacgctac cataatctaa
      361 ataaccatca tattcatcta ctacttatat aattgagttt tattaaactt tttaagtttc
      421 tattctatca aatatttaaa caatctctgc atccgaaaag actacctcgt atagttttac
      481 taacaatatt tttattagcg tgttcaaatc ctgatttctt gtatcaatta ttttctgttc
      541 actttcaata agaaaaaagt ctttacttcc atggataa
//
LOCUS       DASHWW010000210          528 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.220, whole genome shotgun sequence.
ACCESSION   DASHWW010000210 DASHWW010000000
VERSION     DASHWW010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.220"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(5..90)
                     /locus_tag="U2R64_003000"
     tRNA            complement(5..90)
                     /locus_tag="U2R64_003000"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="U2R64_003001"
     tRNA            complement(107..178)
                     /locus_tag="U2R64_003001"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="U2R64_003002"
     tRNA            complement(190..262)
                     /locus_tag="U2R64_003002"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="U2R64_003003"
     tRNA            complement(280..361)
                     /locus_tag="U2R64_003003"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="U2R64_003004"
     tRNA            complement(369..441)
                     /locus_tag="U2R64_003004"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="U2R64_003005"
     tRNA            complement(445..517)
                     /locus_tag="U2R64_003005"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DASHWW010000211          514 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.221, whole genome shotgun sequence.
ACCESSION   DASHWW010000211 DASHWW010000000
VERSION     DASHWW010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.221"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..132)
                     /locus_tag="U2R64_003006"
     CDS             complement(<1..132)
                     /locus_tag="U2R64_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEM8919725.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DASHWW010000212          513 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.222, whole genome shotgun sequence.
ACCESSION   DASHWW010000212 DASHWW010000000
VERSION     DASHWW010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.222"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            244..513
                     /locus_tag="U2R64_003007"
                     /pseudo
     CDS             244..513
                     /locus_tag="U2R64_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          178 a           90 c           76 g          169 t
ORIGIN      
        1 ttattctttt cataaatatt gtaaatagaa gtattaaaaa tatatacaaa aagtattatt
       61 tcgagaaaga taaatatttt caaaaacctt ttcataatcc tcaccctttc ttacactgat
      121 aaatcatgcg tctaatattc aaattatact cgatatgctt tagctaatca gccaactctg
      181 tttgtctact atcattatat caatagacaa tatctgctcc cgtctttatg atcgtgccaa
      241 agcaatcaaa agaaaattgc gaatcactta gatcgaaagt ttactcaaac aaaagcattg
      301 tcagcggttg tcacggattt aacttatgtt cgggtcggga caaattgggc ttatatttgt
      361 ttgatgattg atttattcaa tcgtgaaatt attggccatt cttgcggaaa taaaaaagat
      421 gcgcagcttg taaaaagggc cattcaaagc attccttact cacttcaaga aatcgaactc
      481 ttccatacgg atcgtggaaa agaatttgat aac
//
LOCUS       DASHWW010000213          504 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.223, whole genome shotgun sequence.
ACCESSION   DASHWW010000213 DASHWW010000000
VERSION     DASHWW010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.223"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          226 a           70 c           81 g          127 t
ORIGIN      
        1 ccttaggcag cttttgctgt gtagaaagga ataaataata acgaaagttc aaaagctaat
       61 gccgactatt ctagacatta aagaagacga aaacgaacga taaagaaaga aaagttatga
      121 ataatcgttt attgaaaaaa acttgaaaaa atacaaaaaa ttcgttgacc aagctaaatt
      181 tagttggtat attattactt gtccaaaaga cagaagaaaa tatttattca aaaacataac
      241 aaaaaagtta ttgacatgtt actaacgaca tgataagata actgagtcgt taaaaaagaa
      301 ccacttgcga agcttgattc tatcgaaaaa aacttcaaaa aagttcttga caaataacaa
      361 acgataagtt atgataaatg agttgccgaa agatttcgaa aaacgaaatc gaaaaaaact
      421 tttaaaaaag agttgacaat cgcttgtctc tctgatatga tataaaagtt gctacggcag
      481 ccaaaaatga atcgggaaac actc
//
LOCUS       DASHWW010000214          487 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.224, whole genome shotgun sequence.
ACCESSION   DASHWW010000214 DASHWW010000000
VERSION     DASHWW010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.224"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..>487)
                     /locus_tag="U2R64_003008"
     CDS             complement(<1..>487)
                     /locus_tag="U2R64_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEM8919726.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DASHWW010000215          482 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.225, whole genome shotgun sequence.
ACCESSION   DASHWW010000215 DASHWW010000000
VERSION     DASHWW010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.225"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..408)
                     /locus_tag="U2R64_003009"
     CDS             complement(<1..408)
                     /locus_tag="U2R64_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919727.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP"
BASE COUNT          179 a           78 c           62 g          163 t
ORIGIN      
        1 cggctttcca aatgatgaaa tacctaaatc taacttatta agaaagttga aatttttata
       61 ttcaggaaac catttattaa tttcatgtgc agcacgtaat gcattccctg gagttgtcaa
      121 agagaaaatt aattctgcta agcttattat tgaaaatact gataacttat aattatatcg
      181 tccattgaca atcaaatata aactaactat acttgttaga acaaaaaaac aggcgttgac
      241 ttgttcttga ttagttaaaa atatcaataa aggaatactt acccaatata tttttctatt
      301 tatttcttct cctcttaaga gttgaaaaaa cggataaaaa gttagtaaac taaatgctac
      361 tggccactga tagttcaagg tggttgctct ccaaccggtt tcccccatta ctgtcaatgg
      421 tattaaacag tatatagagc aaaccaataa taaattttta acatttattt tctcaaaaac
      481 at
//
LOCUS       DASHWW010000216          471 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.226, whole genome shotgun sequence.
ACCESSION   DASHWW010000216 DASHWW010000000
VERSION     DASHWW010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.226"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..201
                     /locus_tag="U2R64_003010"
     CDS             <1..201
                     /locus_tag="U2R64_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEM8919728.1"
                     /translation="EISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPE
                     TAIRMEIDQLNRQQRLFGDDNE"
BASE COUNT          180 a           81 c           97 g          113 t
ORIGIN      
        1 gaaatcagca aaaaagtatt ctcaaaattt tggtctgaat ttaaacgtac cttttcaatc
       61 ccaagatatg gcgagttacc tcgtaagaga ttcgatgatg ctgtttcatt tattgaaatg
      121 tggttgccag aaactgcgat ccgtatggaa attgatcaac tgaacagaca acagagactt
      181 tttggtgatg acaatgaata gagctgaagc gctaagaata gggacggcaa ttgctaattg
      241 ctggtggaaa tactataaac caatcatcct aagccaacaa catattgaca agcaaaaagc
      301 atggcaacaa ataaaaaagt gactccgccg gcaagcaaag agtcacaaag aaaacacatc
      361 ataaggagat tttagcatat ggaaaaagaa ctttccactc tagatcaata tttgattgat
      421 cctgattggg gcaagccgaa aattgaggaa acaagtggtc gaaaaatcag a
//
LOCUS       DASHWW010000217          449 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.227, whole genome shotgun sequence.
ACCESSION   DASHWW010000217 DASHWW010000000
VERSION     DASHWW010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.227"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          143 a           90 c           67 g          149 t
ORIGIN      
        1 acactcctct taatatacag tcctattgta taaagtgtta ctatatacat agtaactgta
       61 tacataaaaa aagtcaagta ttagaaaaaa gttcaaaaga tcaagtgtgc gcttcgctcc
      121 cactcccctc gacgttttag tagcctttcc ctcacttcgt tcagtccaag ccaactaaaa
      181 agttttcggg atacattctc cttctcttcc taataatcaa ttaaaatttt aatctttata
      241 tttctgctaa tcactcagga aacagtacag aaaaacaaac acgtatcata gatataaatg
      301 taatggcata gtgcgggttt tattttcagc ctgtatcata gctaaacaaa tcgagttgtg
      361 tgtccgtttt tgggcgttct gctagcttgt ttaaagtctc ttgaatgaat gtatgttcta
      421 agtcaaaaaa ctctgacagc gcctttata
//
LOCUS       DASHWW010000218          418 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.228, whole genome shotgun sequence.
ACCESSION   DASHWW010000218 DASHWW010000000
VERSION     DASHWW010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.228"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            53..>418
                     /locus_tag="U2R64_003011"
     CDS             53..>418
                     /locus_tag="U2R64_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HEM8919729.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHK"
BASE COUNT          150 a           65 c           83 g          120 t
ORIGIN      
        1 aaaaaatcta ttttagtgta aaattgagaa aaaagacaga gaggacagag taatgaatca
       61 ttttaaaggc aaacaattca aaaaagacgt cattattgtc gctgttggtt actacctgcg
      121 ttacaatcta agctatcgtg aagttcagga attgttatat gatcgtggaa taaatgtttg
      181 tcatactacg atttatcgtt gggtgcaaga gtacagcaaa gtcctctatt atctttggaa
      241 gaagaaaaat agacaatcct tctattcatg gaaaatggac gaaacctata tcaaaattaa
      301 gggacgttgg cattatcttt atcgtgcaat tgatgcggac ggcttaacct tagatatctg
      361 gttacgaaag aaacgggata cgcaagcagc ctatgctttc ttaaaacgac tccataaa
//
LOCUS       DASHWW010000219          403 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.229, whole genome shotgun sequence.
ACCESSION   DASHWW010000219 DASHWW010000000
VERSION     DASHWW010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.229"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          141 a           81 c           64 g          117 t
ORIGIN      
        1 ttccgttttt tcatccattc ctttcttccc ccccttacaa ataaataata acctttaaca
       61 accaactcgt aaataggttg gttgttatta tacaaaagga tattagtact cagataaaaa
      121 gttgttagta ctcagataaa aagttgttag tactcagata aaaagttgtt agtactcaga
      181 taaaaagttg ttagtaccct tctgtatccg ttgggagagt aaggctcaac tgccccctaa
      241 aaagggttct aaaaaatctt taaaaaataa ataaaataaa cgcgcgcgcg cgagcaaaat
      301 ttcccgccaa aaaatcaccc actttttaaa ataaacaggt tcgcgcatga tattaaactg
      361 ccaatctagc tccctatggt cgctgtaaga aggagtgatc gct
//
LOCUS       DASHWW010000220          391 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.230, whole genome shotgun sequence.
ACCESSION   DASHWW010000220 DASHWW010000000
VERSION     DASHWW010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.230"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..369
                     /locus_tag="U2R64_003012"
     CDS             1..369
                     /locus_tag="U2R64_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HEM8919730.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
BASE COUNT          127 a           59 c           86 g          119 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt t
//
LOCUS       DASHWW010000221          376 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.231, whole genome shotgun sequence.
ACCESSION   DASHWW010000221 DASHWW010000000
VERSION     DASHWW010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.231"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..374
                     /locus_tag="U2R64_003013"
     CDS             <1..374
                     /locus_tag="U2R64_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8919731.1"
                     /translation="CDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDL
                     LTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKF
                     LNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          142 a           70 c           57 g          107 t
ORIGIN      
        1 tctgtgatga ctttaaggct gtttatcaag ctaactcaaa agaagaagcg aataccttct
       61 tatccggcat gattgagaaa tggaagaaaa actatcctaa agtgacgcag tcactcatag
      121 aaaaccaaga cttattaact ttttatgatt ttccacctag cattcgtaga accatttact
      181 caaccaatct aatcgagtct ttcaataagc aaattaaaag atacagccgt agaaaagagc
      241 agtttcaaaa tgaagaatca ctagaacgct ttctagtcag catttttgat acatacaatc
      301 aaaaatttct aaacagaagc cataaaggtt ttcaacaggt aaccgataca ttagtttcaa
      361 tgtttactga gtaact
//
LOCUS       DASHWW010000222          363 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.denovo.232, whole genome shotgun sequence.
ACCESSION   DASHWW010000222 DASHWW010000000
VERSION     DASHWW010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.denovo.232"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>363
                     /locus_tag="U2R64_003014"
     CDS             <1..>363
                     /locus_tag="U2R64_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEM8919732.1"
                     /translation="TRKLKKCLAKRGLQLSRRRIGRIMKRRGLTSTYTIAHFKGQRTA
                     CNEAKTANVLDRTFTQEQPLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEK
                     KDASLVKEAFGRIPYSLTD"
BASE COUNT          112 a           69 c           85 g           97 t
ORIGIN      
        1 acccgaaaat tgaagaagtg tttagcaaag cgtgggcttc aactcagtcg gcgccgaatc
       61 ggtcgaatca tgaaacgccg cggattgaca tctacctata cgatcgctca ttttaaaggg
      121 caacgaacag cttgtaatga agcgaaaaca gcgaatgtat tagatcggac ctttacacaa
      181 gaacagccat tggaagccat cgttacggat cttacttatg ttcgcgtggg gaaaaagtgg
      241 cattatatct gcttaatact tgatttgttt aatcgagaaa ttattggtta ttcctgtggt
      301 gagaagaaag atgcctcatt ggtaaaagaa gcctttggac ggataccgta ttctttaaca
      361 gac
//
LOCUS       DASHWW010000223         7780 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.101, whole genome shotgun sequence.
ACCESSION   DASHWW010000223 DASHWW010000000
VERSION     DASHWW010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.101"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            245..1213
                     /locus_tag="U2R64_003015"
     CDS             245..1213
                     /locus_tag="U2R64_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEM8919733.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1206..2237
                     /gene="vanA"
                     /locus_tag="U2R64_003016"
     CDS             1206..2237
                     /gene="vanA"
                     /locus_tag="U2R64_003016"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEM8919734.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2243..2851
                     /locus_tag="U2R64_003017"
     CDS             2243..2851
                     /locus_tag="U2R64_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEM8919735.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3279..4190
                     /gene="vanY"
                     /locus_tag="U2R64_003018"
     CDS             3279..4190
                     /gene="vanY"
                     /locus_tag="U2R64_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HEM8919736.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4343..4828
                     /gene="vanZ"
                     /locus_tag="U2R64_003019"
     CDS             4343..4828
                     /gene="vanZ"
                     /locus_tag="U2R64_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEM8919737.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(5115..5444)
                     /locus_tag="U2R64_003020"
     CDS             complement(5115..5444)
                     /locus_tag="U2R64_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8919738.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5749..6078
                     /locus_tag="U2R64_003021"
     CDS             5749..6078
                     /locus_tag="U2R64_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8919739.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            6068..6355
                     /locus_tag="U2R64_003022"
     CDS             6068..6355
                     /locus_tag="U2R64_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8919740.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6634..7197)
                     /locus_tag="U2R64_003023"
     CDS             complement(6634..7197)
                     /locus_tag="U2R64_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8919741.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
BASE COUNT         2566 a         1297 c         1546 g         2371 t
ORIGIN      
        1 atgctggtgt catccaccaa catcaaaaag tatagagcca taatttttta ggaaaatctc
       61 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
      121 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
      181 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
      241 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
      301 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
      361 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
      421 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
      481 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
      541 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
      601 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
      661 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
      721 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
      781 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
      841 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
      901 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
      961 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
     1021 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
     1081 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
     1141 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
     1201 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
     1261 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
     1321 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
     1381 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
     1441 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
     1501 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
     1561 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
     1621 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
     1681 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
     1741 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
     1801 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
     1861 tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga ccaaatcagg ctgcagtacg
     1921 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
     1981 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
     2041 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
     2101 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
     2161 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
     2221 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     2281 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     2341 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     2401 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     2461 tcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     2521 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     2581 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     2641 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     2701 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     2761 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     2821 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     2881 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
     2941 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
     3001 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
     3061 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
     3121 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
     3181 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
     3241 tcatacttcc aactatatag ttaaggagga gactgaaaat gaagaagttg ttttttttat
     3301 tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca ctgttttctc
     3361 aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta gaaaatagtg
     3421 ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat caaggaaatc
     3481 tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca gatatcgtga
     3541 atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt aatatttata
     3601 tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta aagggtggcg
     3661 ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt gtgctttacc
     3721 aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat tcaggtttat
     3781 cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga aagtggatag
     3841 aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa acagagttaa
     3901 caggaattca atatgaacta tggcatattc gctatgttgg tttaccacat agtgcgatta
     3961 tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa gaaaaaacca
     4021 tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt actaaaaata
     4081 ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat atagacggtg
     4141 taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa ggatggcgga
     4201 atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg gtaacgttag
     4261 ctttttaatt taaaacccac gttaactagg acattgctat actaatgata caacttaaac
     4321 aaaagaatta gaggaaatta tattgggaaa aatattatct agaggattgc tagctttata
     4381 tttagtgaca ctaatctggt tagtgttatt caaattacaa tacaatattt tatcagtatt
     4441 taattatcat caaagaagtc ttaacttgac tccatttact gctactggga atttcagaga
     4501 gatgatagat aatgttataa tctttattcc atttggcttg cttttgaatg tcaattttaa
     4561 agaaatcgga tttttaccta agtttgcttt tgtactggtt ttaagtctta cttttgaaat
     4621 aattcaattt atcttcgcta ttggagcgac agacataaca gatgtaatta caaatactgt
     4681 tggaggcttt cttggactga aattatatgg tttaagcaat aagcatatga atcaaaaaaa
     4741 attagacaga gttattattt ttgtaggtat acttttgctc gtattattgc tcgtttaccg
     4801 tacccattta agaataaatt acgtgtaaga tgtctaaatc aagcaatctg atctttcata
     4861 cacataaaga tattgaatga attggattag atggaaaacg ggatgtgggg aaactcgccc
     4921 gtaggtgtga agtgagggga aaaccggtga taaagtaaaa agcttaccta acactatagt
     4981 aacaaagaaa gcccaattat caattttagt gctgaggaat tggtctcttt aataaatttc
     5041 cttaacgttg taaatccgca ttttcctgac ggtaccccca aactaagatt tcatagatag
     5101 attttctgat aactttaaaa aacacgaata gcggaaagga tgtcttcatt cgctaaagag
     5161 taataaacta cttttccatc ttgacgtgat tttgccattc catgtttttt taaaaaacgt
     5221 aaatggtgtg acgttgtagc gacactagca gtaagtattt ctgctaaatc acagacgcac
     5281 atttccttat aggtttctaa agcatagaaa attttaattc tagaaaaatc gctgaaacat
     5341 ttccctaaca caagtaagtt tgaaaaatct ttttgatcca atttattttt tattccattt
     5401 actttttctt tatgtacgac agtcacttgg caaacttttt tcattcatct cacctcacat
     5461 tcaaacgatt atttgaatga agtataccta tttgatcact cttttgtcaa tctaccttaa
     5521 ttccaataca ctattataag caatttcatg tattgaagta aacttacttg caagtgcgtt
     5581 tttgattcca agttaaaaac atattattat tctacataat ttcctaatca aataaaactc
     5641 ctttgaaaat tgttctaaag gagttttatt attttgtatt tctactaaaa atagcgtaca
     5701 atgtaattac taagtaatta cgaaatgtaa aataatggag gaaataatat gattacaaaa
     5761 acaagaaaac aaggaaattc tattatgtta acggtcccta aagaattcga tgtgcccaat
     5821 ggtgttgaag tagaagctaa gcttgtagag aatggtatcc tttatgagtt tgtagagcct
     5881 aaaaaagaat tttttgattt tagtgaagat attttggctg atattctttc agaaggttat
     5941 agcaaacaag agatcttaaa agaatttaga aatagaaaaa atgcgttaac ttctgcattt
     6001 aaatctattg ctgaagatac tgttgcaaat tctaaaccga tgacaaaaga ggagttggca
     6061 gcagaaattg gcttatgaga ttctaccttc taaacacgta ataaagtatc taaaaaaatt
     6121 aaaagagaaa acattaaaag aacaattttt aacgataatt tatgatgaga tagcagttcg
     6181 tcctcattcg ggagaacaaa aaacgggtga tttatcagga atttgggcta ttggattcaa
     6241 gtatgcaggt acgacatatc gcgttgcata tgaaattaaa gataatgcag tgatacctat
     6301 cttactatgt ggaacgcatg aaaattttta tgaacaatta aaaaagatta ggtaagaacc
     6361 caatgtttca acttgagagg atagacgaca ctttaaaaga taatttttaa cagctgagag
     6421 ttgtaatacc ctataatttt aaaccactaa cctatatatt tatgaaaaat agaaaaaatt
     6481 aaaacgcatt ttaagcctct ttcaaattaa aagcttcatc cttatgcaca aagagggctt
     6541 aaaatgcgtt attttatatt gttttttagt aataataaaa aaatcactct aattctccca
     6601 taaatattat agattcctaa agattaaaat agattattcc ctattgtctt ttaagtagcg
     6661 gtagagtgtt gccttgctaa taccagtcat ttccgtaatt tcttttacgc tataaacctg
     6721 acttttatac aattttactg ctcgatcaac atctttctgg ttcactcgtg gacggccacc
     6781 tttacgacct ctcgcacgtg cacttttcaa accttctttg gtacgttcaa caattaaatc
     6841 acgttcgaac tgactaaatg cttggaagac agtcatcatt aagcgtccgt gaggcgtgct
     6901 ggtatcgaag ttttctttca agctcaccag cttaacatgg tgttcttcaa aataggtaac
     6961 aaggtcaatc aaatcctttg tactacgacc caatcgagaa aaactttcta caattaccgt
     7021 atctcccgga cgaattttat cttttaaacg atttagttgg ggacgaaccg ctttggttcc
     7081 cgtcattttc tcagttagga tttcattaca attttgttca ttgagtaagt ctaattgacg
     7141 atttagttct tgtgaacgtg tactcactcg ggcataacca taaatgtatc cactcatgct
     7201 tttcttcctt tcgtacttta attctggctt gattgtatca taaaagggag ttatagatac
     7261 atagttaatg caacaagtta tgatacaaaa tatgacctct tttatttaat aaaagaggtc
     7321 atttcatttt gtctcataat cgattgtttt tgatacgagt gtgtatacga aataaacaaa
     7381 aaaatcttaa gtaaatttct agatacctaa tttaatccta actagtgtat cctaaagtta
     7441 ataacgagtt tatcacaatg aaaattataa aatgctccca tattagatat aacatgcaat
     7501 atttgaatta gaactacaaa atttattcgt tttataaagt aaataatgtt gagatactaa
     7561 ggaatagaat attataagga attgagctga atgtattgga taaaaaaaga ataactttat
     7621 tagagatgga ctataaaaat gctcgtaatt ttcttctgaa gtctgaaagc tatttgaatg
     7681 ctcagctacc agaatatatt agttttgacg aaactttaaa atctgctaaa aaagttttaa
     7741 cttcgccgtt tgtataatta agcgagacaa ataaaaaagc
//
LOCUS       DASHWW010000224         7631 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.103, whole genome shotgun sequence.
ACCESSION   DASHWW010000224 DASHWW010000000
VERSION     DASHWW010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.103"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1070
                     /locus_tag="U2R64_003024"
     CDS             <1..1070
                     /locus_tag="U2R64_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8919742.1"
                     /translation="NALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGE
                     WKETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDS
                     EKFPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSD
                     GSVTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSD
                     RSIFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNI
                     GLKFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHP
                     IFEELLHAFDTRPPVRNEVEE"
     gene            1067..3094
                     /locus_tag="U2R64_003025"
     CDS             1067..3094
                     /locus_tag="U2R64_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919743.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            3091..4113
                     /locus_tag="U2R64_003026"
     CDS             3091..4113
                     /locus_tag="U2R64_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEM8919744.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            4130..5059
                     /locus_tag="U2R64_003027"
     CDS             4130..5059
                     /locus_tag="U2R64_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8919745.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            5304..5420
                     /locus_tag="U2R64_003028"
     CDS             5304..5420
                     /locus_tag="U2R64_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEM8919746.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            5436..7355
                     /gene="tet(M)"
                     /locus_tag="U2R64_003029"
     CDS             5436..7355
                     /gene="tet(M)"
                     /locus_tag="U2R64_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEM8919747.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            7453..>7631
                     /locus_tag="U2R64_003030"
     CDS             7453..>7631
                     /locus_tag="U2R64_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEM8919748.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMGSLSIRTDELCK"
BASE COUNT         2543 a         1298 c         1548 g         2242 t
ORIGIN      
        1 caaatgcatt agcgtccgct tttattggtt cattaggtgg cggaaaatca ttctctaaca
       61 atatgctggt ctattattca gtactctttg gcggacaggc aaccattgtt gacccaaaag
      121 ctgaacgtgg tgaatggaaa gaaaccttac ctgatattgc ccatgaaatc aatattgtta
      181 atctcacgag tgagaacgac aataaagggt tacttgaccc ttatgtgatt ttaaaactcc
      241 cgaaagattc agaaagcctt gccattgata ttctcacgtt cttaacaggt atttccagcc
      301 gagatagcga gaagtttcct gtcctgcgta aagctattcg gagtgtaact caaagcaaac
      361 aacgagggtt gttattggtg attgatgaat tgcgaaaaga agatacgccc atcagcaata
      421 gtattgctga ccatatcgaa agctttgtcg attatgattt tgcccatctg ttattcagtg
      481 atggcagtgt cacccaatcc attagcttgg aaaaacaact caatattatt caagtggcag
      541 atttggtctt acccgattcc aatagctctt ttgaagaata cactaccatg gaattattaa
      601 gtgtggcaat gctgattgtc attagtacct ttgctttaga ctttatccac tctgaccgtt
      661 ccatttttaa aattgttgac cttgatgagg cttggagttt tttacaagtg gcacaaggaa
      721 aagctctatc tatgcgattg gttcgagcag gacgtgccat gaatgcaggg gtctatttcg
      781 ttactcaaaa cgcggacgat ttactagatg aaaagatgaa gaataatatt ggcttgaaat
      841 ttgcctttcg ttccactgac ctagtggaaa tcaaaaagac cttagaattt tttggtgtgg
      901 acaaggaaga tgaaaacaat cagaaacgct tacgtgaatt agaaaatgga caatgtttag
      961 tttcagacat ctatggtcgt gtaggggtta tgcagtttca cccgattttt gaagagttgc
     1021 ttcatgcctt tgataccaga ccgcctgtgc gaaatgaggt ggaagaatga cacaaaaaca
     1081 aaagaaattt cttcactata gttggataac gctcctttgt gtgggcgtta ttttactttt
     1141 attaggcacg ctgggcaatg cagtacaagc gacaggctta gttgatgaaa ccattgatac
     1201 aagcaatgaa tactccaagt atggtttgaa tcaatatcag cttgattatt atgtggacaa
     1261 tagctggggc tggcttccat ggaattggag tgatggcata ggacaatcgg tgatgtatgg
     1321 attgtatgcc attactaatt ttatttggac aatttctctt tatctatcga acgccacagg
     1381 ttatttggtg aaagaagcct atgccttaga tttcattagt caaacatccc aagcaattgg
     1441 cgaaaacatg cagacgattg caggcattac accgaatggc ttttccagtt cagggtttta
     1501 tgtcggtttc ctccttcttt ttattctcat tgttggaatc tatgttgcct atacaggatt
     1561 ggttaagcga gaaacgacga aagtgatacg agctgtttta aactttgtcg tggtgtttat
     1621 tctatcggct tcctttattg cgtatgcacc cgattatatt gcgaaaatca atgatttttc
     1681 caaagatgtc agtaccgcca gtctgaatat tgggacaaaa attgttcttc ctaacacgga
     1741 tagtcaaggg aaagacagtg tggacatgat acgtgacagc ttattctctg ttcaagtaaa
     1801 gcaaccatgg ctattgcttc aatatggctc cactgatgta gaagcgttag gggaagaacg
     1861 tgtggaaagt ttattgtcta ccagtccaga tacaaacaat ggtgaagata gagaaaatgt
     1921 agtgattgaa gaaattgaag atcatgacaa tacctattta accctaccga agacgatttc
     1981 cagattagga acagtcttct ttttgtttgt attcaatatt ggtatctcga tttttgtttt
     2041 ccttctaaca ggaatcatga ttttttcgca agtgctattt attattttcg ctatgttttt
     2101 gccaatcagt ttcctattaa gtatgttgcc gagttttgat ggcatgggca ggcatgccat
     2161 taccaagtta tttaatgtga ttatgacaag ggctggtatt accttgatta ttaccgttgc
     2221 ctttagtatt tccactatgc tttattcgct gtcagcaagt tctccctttt tcatgattat
     2281 gtttttacaa attgtgacct ttgcagggat ttattttaaa ctgggcgatt taatgagcct
     2341 attcacttta caaagcaacg actctcaaaa catgggcaga caagtgtttc gcagacctcg
     2401 tcaaatgatg aatcgacaaa ccagaagatt tcaacgcagt atgagtaaga tttttcgtgg
     2461 aaaagcaggg tcaacgaagc aaaagacaat gacaacaaag cagaatcaaa ccaataaagc
     2521 taaccatact cgtcaaaatg aacggactac accaaagaaa gaaacagcac tttccaatgt
     2581 gaaaaagcaa caaggcggta tcgggcaacg attaggtgaa aagacagccc atgtattgga
     2641 cacgaaaaat cgtctagtca ataaaagaaa gcaggcaaaa caacagatac aggcgacacc
     2701 aacccatgtc aaatatgccc ttcatcaagg aaaagagaat gtcactcata atgtaacaga
     2761 ctttaaacaa tctatggcag ataccaaagc tcaacgcaaa caacagcgta tgaaccagca
     2821 ggagcaaaaa cgaaagaaca ttgctcaaaa gcgtttggag ctggataaag caaaagaaaa
     2881 aagacgaaaa gaaaacccat catctcctgt tcagaataac cagcagcatg ttcgcaagcg
     2941 tcagcaaacc gtcacgcctg ttttgtcaca aaacactaaa cgtgaaaatc atcagcgacc
     3001 attgaaaaaa gagcaaaaac aaaagacacc accgaagcaa ttcaatcaga ggaagctaaa
     3061 taaaagaacg gataagcgag gacaacaaac atgaagctaa aaataacagt gatttgtagt
     3121 gtggtcttct ctctcttctt ttttctctta ttattcctag tcattttctt tgcagatgat
     3181 acggacagtg gcgaaaacaa caaggattct tctattccac aaggcggtgt gaccgtttca
     3241 ccagaagtgt tggcacaccg tccgttgatt gaaaaatatg gtaaggaata tgggattgaa
     3301 gactatgttt cttatatctt agccattatg caagtggaat cgggcggtac agcagaagat
     3361 gttatgcaaa gttccgaatc tttgggttta ccgcccaaca gtttgagtac cgaagagtcc
     3421 atcaaacaag gggttaaata tttcagtgaa ttattaacca gtgcagaaca acaaggagtg
     3481 gatatagatt ctgttatcca atcttataat tatggcggtg gctttttaaa ttatgtgagg
     3541 agtcatggga aaaaatatac ctatgaatta gccgaacagt tttctaaaga gaagtcgggt
     3601 ggtcaaaaag cagactatcc caatcctata gccatacctg tgaatggtgg ttggcgatat
     3661 aactatggaa atcagtttta tgttcagttg gtttcacaat acctaaccga cacttcccca
     3721 acagaatttg atggtgaaac cgtgcaagtc attatggacg aagccttgaa atacgaaggg
     3781 tttccctatg tctttggagg ggcgtcgcct accacctctt ttgattgtag tggcttaata
     3841 caatgggtgt atgacaaagc tggcatttct ctccctcgtg tcgcccaaga tcagtatgac
     3901 gctacgcaag aaatctctat ggaagaagcc caagcaggcg accttatctt ctttcattca
     3961 acctataatg caggcacata tgtgactcat gtggcgatat atttagaggg aaatcgcttt
     4021 tatcatgcag gcgacccaat cggttatggc gacttaagca gtcgttattg gcaagaccat
     4081 ctgattgggg ctagacgtgt tattcataac taagaaagga atgaatcaaa tgattataaa
     4141 aatcgagcga aaagaaaaga aggagaaacc aaagaaatct aaaaaaccga gcaagcaaag
     4201 aaaagttccg atgattaaag ttggcacgca taagaaatta acctttgttt tatgggtttt
     4261 attgattggt agtgtcggat ttggaatcta taaaaatttt actgccattg acactcatac
     4321 tgtccgtgaa acagaaatca ttaaacagca gattgtcgat accaaccaag tagaaagttt
     4381 tgtgaaatcc tttgcgaaag actacttttc gtggcaacaa tcccaagaag ccattgataa
     4441 acgaaatgaa aaattgaccc attatttgac ggaagaattg caggtattaa atgaagaaat
     4501 gattcgtaag gatattccta ctagttctag tgtgaacgat atacaggtgt ggcaggtttc
     4561 tcaagtgaat gagaacacct ttgaggtact gttttctgtt gaacaagtta ttaccgaaga
     4621 caaagacaag gaaactatat cgtctagctt tcatgtggtt gtccatatag atgaatcaga
     4681 taatatggtt attatcaaaa atccgacaat gagtaagaaa cctcaaaaat cggactacca
     4741 acccaaacag ctagaaagtg accatacagt agatacagaa acgatggacg aaatcactag
     4801 ctttttagaa acgttcttcc agctctatcc taccgccaca gaaaaagaat tgacttacta
     4861 tgtaagtaat catgtgttac ctatgattaa caaggaatat gttttcgagg aattggtgaa
     4921 tcctatcttt accagaaaag ataaccaagt aatcgtgaat gtcgctgtga aatatttaga
     4981 tcaagaaaca aaggcaaccc aaatctcgca atttgagttg atattagaaa aacaagataa
     5041 ttggaagatt gtaaaataac aaatattggt acatgattac agatactttg taatcatgta
     5101 ctctttttga taaaaaattg gagattcctt tacaaatatg ctcttacgtg ctattattta
     5161 agtgactatt taaaaggagt taataaatat gcggcaaggt attcttaaat aaactgtcaa
     5221 tttgatagcg ggaacaaata attagatgtc cttttttagg agggcttagt tttttgtacc
     5281 cagtttaaga atacctttat catgtgattc taaagtatcc agagaatatc tgtatgcttt
     5341 gtatacctat ggttatgcat aaaaatccca gtgataaaag tatttatcac tgggattttt
     5401 atgccctttt gggtttttga atggaggaaa atcacatgaa aattattaat attggagttt
     5461 tagctcatgt tgatgcagga aaaactacct taacagaaag cttattatat aacagtggag
     5521 cgattacaga attaggaagc gtggacaaag gtacaacgag gacggataat acgcttttag
     5581 aacgtcagag aggaattaca attcagacag gaataacctc ttttcagtgg gaaaatacga
     5641 aggtgaacat catagacacg ccaggacata tggatttctt agcagaagta tatcgttcat
     5701 tatcagtttt agatggggca attctactga tttctgcaaa agatggcgta caagcacaaa
     5761 ctcgtatatt atttcatgca cttaggaaaa tggggattcc cacaatcttt tttatcaata
     5821 agattgacca aaatggaatt gatttatcaa cggtttatca ggatattaaa gagaaacttt
     5881 ctgccgaaat tgtaatcaaa cagaaggtag aactgtatcc taatatgtgt gtgacgaact
     5941 ttaccgaatc tgaacaatgg gatacggtaa tagagggaaa cgatgacctt ttagagaaat
     6001 atatgtccgg taaatcatta gaagcattgg aactcgaaca agaggaaagc ataagatttc
     6061 agaattgttc tctgttccct ctttatcatg gaagtgcaaa aagtaatata gggattgata
     6121 accttataga agttattact aataaatttt attcatcaac acatcgaggt ccgtctgaac
     6181 tttgcggaaa tgttttcaaa attgaatata caaaaaaaag acaacgtctt gcatatatac
     6241 gcctttatag tggagtacta catttacgag attcggttag agtatcagaa aaagaaaaaa
     6301 taaaagttac agaaatgtat acttcaataa atggtgaatt atgtaagatt gatagagctt
     6361 attctggaga aattgttatt ttgcaaaatg agtttttgaa gttaaatagt gttcttggag
     6421 atacaaaact attgccacag agaaaaaaga ttgaaaatcc gcaccctcta ctacaaacaa
     6481 ctgttgaacc gagtaaacct gaacagagag aaatgttgct tgatgccctt ttggaaatct
     6541 cagatagtga tccgcttcta cgatattacg tggattctac gacacatgaa attatacttt
     6601 ctttcttagg gaaagtacaa atggaagtga ttagtgcact gttgcaagaa aagtatcatg
     6661 tggagataga actaaaagag cctacagtca tttatatgga gagaccgtta aaaaatgcag
     6721 aatataccat tcacatcgaa gtgccgccaa atcctttctg ggcttccatt ggtttatctg
     6781 tatcaccgct tccgttggga agtggaatgc agtatgagag ctcggtttct cttggatact
     6841 taaatcaatc atttcaaaat gcagttatgg aagggatacg ctatggttgc gaacaaggat
     6901 tatatggttg gaatgtgacg gattgtaaaa tctgttttaa gtacggttta tactatagcc
     6961 ctgttagtac tccagcagat tttcggatgc ttactcctat tgtactggag caagccttta
     7021 gaaaagctgg aacagaattg ttagagccat atcttagttt taaagtttat gcaccacagg
     7081 aatatctttc acgggcatat aacgatgctc ccaaatattg tgcaaatatc gtaaatactc
     7141 aactgaaaaa taatgaggtc attattattg gagaaattcc tgctcgatgt attcaagatt
     7201 atcgcaatga tttaactttt tttacaaatg ggcttagtgt ttgtttagca gagctaaaag
     7261 gatatcaggt taccactggc gaacctgttt gccagacccg tcgtctaaat agtcggatag
     7321 ataaagtaag atatatgttc aataaaataa cttagtgcgt tttatgttgt tatataaata
     7381 tggtttctta ttaaataaga tgaaatattc tttaatatag atttgaatta aagtggaaag
     7441 gaggagattg ttattataaa ctacaagtgg atattgtgtc ctatttgtgg aaataaaaca
     7501 agactacgaa tacgagtgga tactatactt aaaaatttcc ctttatactg ccccaaatgt
     7561 aagaacgaaa ctttaattaa tgttcaaaaa atgggctctt tgtcaataag gactgatgag
     7621 ttgtgcaaaa t
//
LOCUS       DASHWW010000225         6752 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.107, whole genome shotgun sequence.
ACCESSION   DASHWW010000225 DASHWW010000000
VERSION     DASHWW010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.107"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            111..194
                     /locus_tag="U2R64_003031"
     CDS             111..194
                     /locus_tag="U2R64_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEM8919749.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="U2R64_003032"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="U2R64_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEM8919750.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="U2R64_003033"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="U2R64_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1649..2314
                     /locus_tag="U2R64_003034"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="U2R64_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="U2R64_003035"
     CDS             2350..2595
                     /locus_tag="U2R64_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8919751.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="U2R64_003036"
     CDS             2698..3567
                     /locus_tag="U2R64_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEM8919752.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="U2R64_003037"
     CDS             3548..4282
                     /locus_tag="U2R64_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8919753.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5230
                     /gene="ant(6)"
                     /locus_tag="U2R64_003038"
                     /pseudo
     CDS             4315..5230
                     /gene="ant(6)"
                     /locus_tag="U2R64_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
     gene            5227..5769
                     /gene="sat4"
                     /locus_tag="U2R64_003039"
     CDS             5227..5769
                     /gene="sat4"
                     /locus_tag="U2R64_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEM8919754.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5862..6656
                     /locus_tag="U2R64_003040"
                     /note="aph(3')-IIIa"
     CDS             5862..6656
                     /locus_tag="U2R64_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEM8919755.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2366 a         1016 c         1407 g         1963 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaacctagaa ccgtttatat ctaatgatga
     4501 ctggcttaat caatttggga atataataat gatgcaaaag ccggaggata tggaattatt
     4561 cccacctgaa gaaaagggat tttcctatct tatgctattt gatgattaca ataaaattga
     4621 tcttacctta ttgcccttgg aagagttaga taattaccta aagggcgata aattaataaa
     4681 ggttctaatt gataaagatt gtagaattaa aagggacata gttccgactg atatagatta
     4741 tcatgtaaga aagccaagcg caagggagta tgatgattgc tgcaatgaat tttggaatgt
     4801 aacaccttat gttattaaag gattgtgccg taaggaaatt ttatttgcta ttgatcattt
     4861 taatcagatt gttcgccatg agctgctgag aatgatatca tggaaggtcg gcatcgaaac
     4921 aggctttaaa ttaagtgtag gcaagaacta taagtttatt gaaaggtata tatccgagga
     4981 tttgtgggag aaacttttgt ccacctaccg gatggattcc tatgaaaaca tatgggaagc
     5041 attatttcta tgccatcaat tgttcagggc ggtatccggt gaggtggcgg aaaggcttca
     5101 ttatgcctat ccggagtatg ataggaatat aacaaaatat accagggaca tgtataaaaa
     5161 atacactggt aaaaccggct gcctggatag cacatatgcc gctgatatag aagagaggcg
     5221 ggaacagtga ttacagaaat gaaagcaggg cacctgaaag atatcgataa acccagcgaa
     5281 ccatttgagg tgataggtaa gattataccg aggtatgaaa acgagaattg gacctttaca
     5341 gaattactct atgaagcgcc atatttaaaa agctaccaag acgaagagga tgaagaggat
     5401 gaggaggcag attgccttga atatattgac aatactgata agataatata tctttactac
     5461 caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat
     5521 atagaagata tcgccgtatg taaggatttc agggggcaag gcataggcag cgcgcttatc
     5581 aatatatcta tagaatgggc aaagcataaa aacttgcatg gactaatgct tgaaacccag
     5641 gacaataacc ttatagcttg taaattctat cataattgtg gtttcaaaat cggctccgtc
     5701 gatactatgt tatacgccaa ctttgaaaac aactttgaaa aagctgtttt ctggtattta
     5761 aggttttaga atgcaaggaa cagtgaattg gagttcgtct tgttataatt agcttcttgg
     5821 ggtatcttta aatactgtag aaaagaggaa ggaaataata aatggctaaa atgagaatat
     5881 caccggaatt gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt
     5941 ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa cctatattta aaaatgacgg
     6001 acagccggta taaagggacc acctatgatg tggaacggga aaaggacatg atgctatggc
     6061 tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga acggcatgat ggctggagca
     6121 atctgctcat gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa
     6181 gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag gctctttcac tccatcgaca
     6241 tatcggattg tccctatacg aatagcttag acagccgatt agccgaattg gattacttac
     6301 tgaataacga tctggccgat gtggattgcg aaaactggga agaagacact ccatttaaag
     6361 atccgcgcga gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt
     6421 cccacggcga cctgggagac agcaacatct ttgtgaaaga tggcaaagta agtggcttta
     6481 ttgatcttgg gagaagcggc agggcggaca agtggtatga cattgccttc tgcgtccggt
     6541 cgatcaggga ggatatcggg gaagaacagt atgtcgagct attttttgac ttactgggga
     6601 tcaagcctga ttgggagaaa ataaaatatt atattttact ggatgaattg ttttagtacc
     6661 tagatttaga tgtctaaaaa gctttaacta caagcttttt agacatctaa tcttttctgg
     6721 ctctttgtca aatgatgttg gtaaagagaa at
//
LOCUS       DASHWW010000226         5674 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.120, whole genome shotgun sequence.
ACCESSION   DASHWW010000226 DASHWW010000000
VERSION     DASHWW010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.120"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..511)
                     /locus_tag="U2R64_003041"
     CDS             complement(<1..511)
                     /locus_tag="U2R64_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEM8919756.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQE"
     gene            637..1758
                     /locus_tag="U2R64_003042"
     CDS             637..1758
                     /locus_tag="U2R64_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEM8919757.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2016..3518
                     /gene="eat(A)"
                     /locus_tag="U2R64_003043"
     CDS             2016..3518
                     /gene="eat(A)"
                     /locus_tag="U2R64_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEM8919758.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            3546..4112
                     /locus_tag="U2R64_003044"
     CDS             3546..4112
                     /locus_tag="U2R64_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8919759.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            4323..5384
                     /locus_tag="U2R64_003045"
     CDS             4323..5384
                     /locus_tag="U2R64_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEM8919760.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            5387..>5674
                     /gene="murQ"
                     /locus_tag="U2R64_003046"
                     /gene_synonym="yfeU"
     CDS             5387..>5674
                     /gene="murQ"
                     /locus_tag="U2R64_003046"
                     /gene_synonym="yfeU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="catalyzes the cleavage of the lactyl ether moiety
                     of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate;
                     involved in MurNAc dissimilation pathway; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEM8919761.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPE"
BASE COUNT         1910 a          994 c         1232 g         1538 t
ORIGIN      
        1 cttcttgaaa gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct
       61 ctagttcgat ttctccatca cctaacaatg tgacttttcc gggaccagct agaccagctg
      121 tccacatcgt gatcccaaat aagatatttt tctttggcac atatttttcc agtacatctt
      181 catgacctaa tccatttagt aaacacaaaa cataagtatt gtcagtaata atggattgga
      241 tcgaacaaaa catatcatct aattgattgg cttttgttaa tgctacgatc aagtccacgt
      301 gttcgttgct ttcgatgatt tcttctggtg aatagattgg cagttttgcg accacttctt
      361 taccgttaaa gtcagcaatc aacccatttg tacgaatggc ttcaatgtga gcaggccaac
      421 gatcgatcaa gaggacctca tttccgcttt gatgtagcat caatccgatt cggctgccca
      481 ttgctccggc cccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc
      541 ccttttagta tatagaaaaa tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa
      601 aaagtgtctt acttaagaag aaagtgaggg atacagatgg atattttggc ggcaattgat
      661 tcatttaaag gaagtgcttc ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa
      721 gatcgtaaag gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa
      781 gcaatctatt acgcgctcag gggaacatgg cgtaccattg atgggatgga tctcttattc
      841 cgtcagcgaa aaatcagcta tttattgaca acttggcaag gaaaaaacac cgcagtcatc
      901 gaatctgcac aagcattggg gttagatcta cttgataaac caacggatca aactatccga
      961 cttgcttcca gttatgcctt aggagaactt attaaagatg cactgcttca agaagtagaa
     1021 caaattattg tcactttagg aggaagcggg tgtagcgatg gtggtctagg attactccaa
     1081 tccttgggtg cttctttaga agggtacaca gaaggaaatc ctttattatc tactaaaaaa
     1141 cttcattttg atcgaagaaa cgttcttgtt tctaaagtaa aattgattat cgctgcagat
     1201 gttaccaatc catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga
     1261 ggaatagata cgacgctagc tttcttagat aaacaagcag gaaagattgc tcagcaaata
     1321 aaagatttct gggaggtgga tttagatgat attccaggaa gtggagcagc aggcggtatt
     1381 ggtggagccc tttttttgtt gggagcgaag atggtttctg gtttcgattt agtcagccaa
     1441 atcactggat tggaaaaaaa gatcgaacaa gcagatgtca tcattacagg agaagggcgg
     1501 atcgatcagc aaacgatcca cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa
     1561 tatcgaaaac caataatcgc tatttgcgga agtagagacc aagagctaga aggactttct
     1621 gattttctcc caattgtctt aagtattcat ttgggtccaa taggtttaga agaagcaatg
     1681 gaacacaggc aaacattaga aaaaacaaaa atcttaggac agacacttag cagatttttc
     1741 accatcctcc cgaagtagtt gacaaaatca ttttctttat gctatcgtaa tttcaaatat
     1801 aggacaaagt gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca
     1861 gactgtacct tgtggagaca aggaagcagt gtgcagattt tcgggattgg cttggttttt
     1921 tcgatgtatg ggtctttttg tgtgtatcca acccttgcat cctctttagc cagttctgaa
     1981 aataggactg gtcttttttt acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc
     2041 tgacattcgg ctacgacagc caaggcacat tattatttga acaagcaaat ctaaattttg
     2101 acacacaatg gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga
     2161 atattctaca aaacaaacta ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct
     2221 atttcccgca acagacaaaa gataaagaac gtttaaccta ttacgtgtta aatgatatta
     2281 cggattttga gatatgggaa atcgaaagag agctccaatt gatgcaaaca gatcctgaaa
     2341 tcttatggag agaattcagc acactatcgg ggggagagaa gacaaaagtc ctactggcac
     2401 ttttatttgt ggatgacact catttcccgt taatcgatga accaacgaat catttggata
     2461 tctctggtag aaaacaagta gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg
     2521 tcagccatga ccggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaaa
     2581 gtcaactgga actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg
     2641 atgaatttga aatggctcaa aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa
     2701 cagcagctga aaaagccgaa tggtctcgtt cccgagaagg agataaaaca aagaaacaag
     2761 tcggattcat cgatactgaa tctagacgag tgaataaagg agcagtgggt gctgatgctg
     2821 cacggacgat gaaacgatcc aaagcaatcg tgaatcggat ggagacccag atcagcgaga
     2881 aagaaaaact attaaaagat atcgaatata tcgattcttt gacgatgaat agccaagcgt
     2941 ctcaccataa gcgactttta agcgtagaag atcttcaatt agggtatgaa aatctgttat
     3001 tcgagccaat tcattttaca atcgagcctc atcagcgggt ggcgatttca ggtcctaacg
     3061 gtgcaggaaa gtcatccatt atccattatc ttctgggggc attcaacggc aaggttatag
     3121 gagaaaaata ccagccaaaa catctgagca ttagttatgc aagccaaaat tatgaagaca
     3181 atcgaggaac gttggcggaa tttgcagaga aaaaccaagt agactaccaa gcatttttga
     3241 acaacctccg aaagcttggg atggaaagag atgtttttca taacaagatc gagcagatga
     3301 gtatgggcca acggaaaaaa gtggaattgg ctaaatcttt atcacagcca gctgaactat
     3361 atacatggga tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac
     3421 tgatcttgaa cgtgaaacct gccatgttac tagtggaaca tgatcaaacc ttcctggata
     3481 aagtatctac tgagattatt tctcttgaga gaatctaacc cttgtaatct caagaacaac
     3541 aaggtatggt taaggggaac tttgccaacg aaggagagaa tcacatgctt tatgtaacga
     3601 gacacggaga aacaacttgg aacgcacaag gattagtttg cggacgggca gatgtgccgc
     3661 tgactgaaaa aggacagatg caggcacaga aactagcaga aaaggtagta gatttgcctg
     3721 ttccaatcac gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag
     3781 ttgctgatcg tctcagcttg ccgctgaccg ttgatgaacg attggtagaa atggattttg
     3841 gggattatga tggactgcca agcaaagatg agaactttca aaaagcacgt ttagcgttcg
     3901 ctgtacgatt cccaaatggg gagtcagtct tagatgtgta tgcacggatc gttcctttat
     3961 tgaaagaatg catcgaagac gaagaaaatg tctatctgtt agtttgccat aatgccttga
     4021 taagagtgat caatgcttat tttcatccga tgcctaatga ggggttcttt acattcatgg
     4081 tagataatac agaattggtt tcttatgagt aattatgttt ttgtgttatt taaataaaat
     4141 atttcaaggc actgcttttg cttagcagtg ccttttttag gttatgacaa ttcttttgat
     4201 aatataaact caacctttag aaatgaaatt taattatttt aataaaagta ttgaaatttt
     4261 gtttctttag atatatactc tagtcataga aatgaagacg gatacagaaa aagagggata
     4321 atatgtttgg cttttcaata tttatgaacg attctttgtc agaagagaag aaacagtata
     4381 tccgccaaat ggcatccaat ggctttgtcg gtattttcac ttccatgcat ataccagaag
     4441 atgatgtttc ggcatatcaa aagcgattga tcgaactagg aagcgaagcg aaaaagaata
     4501 aactagaatt gatggtcgat atttcaggag aggcattgga acgagcgggt ttttcattag
     4561 aagatctaac gcctttgaaa gcaattggtg taacaggttt aagaatggat tatcatattt
     4621 ccaatcagca gattgccgac tggtcacatc aattgaaaat cagtttgaat gctagcacga
     4681 tcacgcctaa agatatcgat gaattgaaag aagcagaagc tgatttctca cagattgaag
     4741 cttggcataa ttattatcca cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa
     4801 aaaatcaatg gctcaaaatt caaggtctcc ttgtccaagg ttttgtacca ggagatacag
     4861 agttgagagg cccactatat caaggattgc caactttgga agaacatcga gggatccatc
     4921 ctcttgcagg cgctctagat ctattagcaa gtaacacgga tattgtttac atcggagatg
     4981 caggtctgtc agaaaacgtt caggagcaat ttgcttcttt ccaaaaagaa cagacagtct
     5041 tgctccatac ggaacctgta gatgaagaat tttacgaata tatattaggg aagcatacga
     5101 atcggcaaga cgatgcaaga gatgtcatac gaagcgtaga tgcacgtttt cgagagattc
     5161 cgcctatccc agcaagaaat acagctacgc gtatgaaagg gtctattact ttagataacg
     5221 aaaagtattt gcgctatatg ggtgagatcc aattaaccaa atatgatttg ccagcggatg
     5281 aaaaagtgaa tgtagtagct aaagttatca aagaagagct accattgatc aaccaaatca
     5341 aagctggtat gaactatcaa tttataagaa aagaaggaag ataaaaatga gcaaaatcaa
     5401 tttagagaac ctaacaacgg aacgcagaaa ccaagaaact tttggattag atgagatgag
     5461 tatttctcaa gccgttcaac taatgaacaa agaagatcag aaagtggccg ctgcggttga
     5521 aaaagaactg acaagtatcg aaccagtgat tgctaacacg attgagtcct ttaaaaaagg
     5581 tggacgtctg atttatatgg gagccggaac aagtggaaga ctaggtgtgt tagatgctgc
     5641 tgaatgcgta ccgacattcg gtgtagaacc ggaa
//
LOCUS       DASHWW010000227         2242 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.150, whole genome shotgun sequence.
ACCESSION   DASHWW010000227 DASHWW010000000
VERSION     DASHWW010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.150"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..148
                     /locus_tag="U2R64_003047"
     CDS             <1..148
                     /locus_tag="U2R64_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8919762.1"
                     /translation="LIVDLKLCNRTNYAVKLYKEGNMTVNQICEITNVSRASLYRKLS
                     EVNN"
     gene            362..1057
                     /gene="vanR"
                     /locus_tag="U2R64_003048"
     CDS             362..1057
                     /gene="vanR"
                     /locus_tag="U2R64_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEM8919763.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1035..2189
                     /locus_tag="U2R64_003049"
     CDS             1035..2189
                     /locus_tag="U2R64_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEM8919764.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          757 a          409 c          475 g          601 t
ORIGIN      
        1 tttgatagta gatttaaaac tttgcaacag aaccaattat gcggtaaagc tatataaaga
       61 aggaaatatg actgtaaatc aaatttgtga aattactaat gtatctaggg cttcattata
      121 caggaaatta tcagaagtga ataattagcc attctgtatt ccgctaatgg gcaatatttt
      181 taaagaagaa aaggaaacta taaaatatta acagcctcct agcgatgccg aaaagccctt
      241 tgataaaaaa agaatcatca tcttaagaaa ttcttagtca tttattatgt aaatgcttat
      301 aaattcggcc ctataatctg ataaattatt aagggcaaac ttatgtgaaa gggtgataac
      361 tatgagcgat aaaatactta ttgtggatga tgaacatgaa attgccgatt tggttgaatt
      421 atacttaaaa aacgagaatt atacggtttt caaatactat accgccaaag aagcattgga
      481 atgtatagac aagtctgaga ttgaccttgc catattggac atcatgcttc ccggcacaag
      541 cggccttact atctgtcaaa aaataaggga caagcacacc tatccgatta tcatgctgac
      601 cgggaaagat acagaggtag ataaaattac agggttaaca atcggcgcgg atgattatat
      661 aacgaagccc tttcgcccac tggagttaat tgctcgggta aaggcccagt tgcgccgata
      721 caaaaaattc agtggagtaa aggagcagaa cgaaaatgtt atcgtccact ccggccttgt
      781 cattaatgtt aacacccatg agtgttatct gaacgagaag cagttatccc ttactcccac
      841 cgagttttca atactgcgaa tcctctgtga aaacaagggg aatgtggtta gctccgagct
      901 gctatttcat gagatatggg gcgacgaata tttcagcaag agcaacaaca ccatcaccgt
      961 gcatatccgg catttgcgcg aaaaaatgaa cgacaccatt gataatccga aatatataaa
     1021 aacggtatgg ggggttggtt ataaaattga aaaataaaaa aaacgactat tccaaactag
     1081 aacgaaaact ttacatgtat atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt
     1141 atattcgttc aatgatccga gggaaacttg gggattggat cttaagtatt ttggaaaaca
     1201 aatatgactt aaatcacctg gacgcgatga aattatatca atattccata cggaacaata
     1261 tagatatctt tatttatgtg gcgattgtca ttagtattct tattctatgt cgcgtcatgc
     1321 tttcaaaatt cgcaaaatac tttgacgaga taaataccgg cattgatgta cttattcaga
     1381 acgaagataa acaaattgag ctttctgcgg aaatggatgt tatggaacaa aagctcaaca
     1441 cattaaaacg gactctggaa aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa
     1501 atgacgttgt tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc attatcggtt
     1561 atttgagcct gcttgacgag gctccagaca tgccggtaga tcaaaaggca aagtatgtgc
     1621 atatcacgtt ggacaaagcg tatcgactcg aacagctaat cgacgagttt tttgagatta
     1681 cacggtataa cctacaaacg ataacgctaa caaaaacgca catagaccta tactatatgc
     1741 tggtgcagat gaccgatgaa ttttatcctc agctttccgc acatggaaaa caggcggtta
     1801 ttcacgcccc cgaggatctg accgtgtccg gcgaccctga taaactcgcg agagtcttta
     1861 acaacatttt gaaaaacgcc gctgcataca gtgaggataa cagcatcatt gacattaccg
     1921 cgggcctctc cggggatgtg gtgtcaatcg aattcaagaa cactggaagc atcccaaaag
     1981 ataagctagc tgccatattt gaaaagttct ataggctgga caatgctcgt tcttccgata
     2041 cgggtggcgc gggacttgga ttggcgattg caaaagaaat tattgttcag catggagggc
     2101 agatttacgc ggaaagcaat gataactata cgacgtttag ggtagagctt ccagcgatgc
     2161 cagacttggt tgataaaagg aggtcctaag agatgtatat aattttggct ctttgtcaaa
     2221 tgatgttggt aaagagaaat ct
//
LOCUS       DASHWW010000228         1930 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.159, whole genome shotgun sequence.
ACCESSION   DASHWW010000228 DASHWW010000000
VERSION     DASHWW010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.159"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            86..1564
                     /gene="msr(C)"
                     /locus_tag="U2R64_003050"
     CDS             86..1564
                     /gene="msr(C)"
                     /locus_tag="U2R64_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEM8919765.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1611..>1930
                     /locus_tag="U2R64_003051"
     CDS             1611..>1930
                     /locus_tag="U2R64_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEM8919766.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIP"
BASE COUNT          655 a          322 c          413 g          540 t
ORIGIN      
        1 gatgcagttt ttttgcaaac agatttttct gctctttttt agtatcgata attgttgttt
       61 tacatgaaat aggagtgtaa aacatatgga aaatttagca gtaaatataa caaatctaca
      121 agtcagcttt ggcaaccagc tagaactatc tattgattct cttcgtgtct atcagcaaga
      181 tcgtataggg atcataggag aaaatggtgt cggtaaatcg actttgctca aactaatagc
      241 cggtgaactt tttcccgatc atgggaaaat ccaaacagag atcaccttca actacctgcc
      301 tcaattaacc tatctcgctg aagcaaagga cctaaatttg gaattagcca gtcatttcca
      361 gttaagactg gaagaaactt cagagcggaa atggagcgga ggggaagaac gaaagatcga
      421 gttgatacgt cttctttctt cttatgaaca agggatgctt ctagacgagc caacaaccca
      481 tctagataga aaaagtattg atcgactgat tgaagagctt cgttattatt atggtacgct
      541 ggtttttgtt agtcatgatc gctattttct agatgagcta gcatcgaaaa tctgggaagt
      601 aaaagacgga gaaatccgag agttttcggg gaattatagt gcctatctca ctcaaaagga
      661 attggagaaa aagactcagc tacgagaagc agagtcgatc atgaaagaga aaaaacgatt
      721 ggaaaaatcg atccaagaaa agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa
      781 aaagaaaaag caacaaatca gaccggatcg gttgtcttcc tctaaacaaa aagacagtgt
      841 acaaaaagcc atccaaaaga atgcgaaaac attagagaga agactccaaa aaataggaga
      901 aacaaccaag ccgcagcaga tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact
      961 ccacagccgc tatcccatca tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt
     1021 actggtaaat ggtgattttc agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa
     1081 tggttcaggt aagacaacct tattagaaca tatccgcaaa caaggagaag gaatccttct
     1141 ctctccgaaa gtaagctttc aagtatatca gcaaaagggt tatcaaatga catctgaaga
     1201 atccatcatt cgttttgtca tgagacaaac agagttttca gaatcgcttg tccgtagttt
     1261 gctgaatcac ttagggtttg ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg
     1321 gggagaagcg acccgtctga cgattgcttt gctttttact aagccaagta atgtgttgct
     1381 gttagatgaa ccgactaatt ttattgatat ggcaacgatc gaagctttag agaagctaat
     1441 gcaaatatat ccgggaacga ttttgtttac ttctcatgat tcttactttg tcgagcgtac
     1501 ggctgatgaa gtttatgaaa taaaagggca gaaaataaaa aaagtactta cgagaaattt
     1561 ttaaatgtgc tacgatgatt ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa
     1621 ataaaaaaga aggaataatt tttacaacaa tgatgtgttt tttgatggtc ttggggatga
     1681 gcgcgtataa tttatggctg catcaagatc ttcatttatc aagtttgttg attggtctag
     1741 tgcctggatt cgtggtggct ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa
     1801 aaattgcctt taaactacca gtaaatccag aaagcaaggt ccaaatgatc ttaactattt
     1861 catgcttgat ggttttagga atggtgacat gtatgtcttt attcggtgtg atcatggaac
     1921 aaggaatacc
//
LOCUS       DASHWW010000229         1384 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.178, whole genome shotgun sequence.
ACCESSION   DASHWW010000229 DASHWW010000000
VERSION     DASHWW010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.178"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1348
                     /locus_tag="U2R64_003052"
     CDS             <1..1348
                     /locus_tag="U2R64_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HEM8919767.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          578 a          116 c          233 g          457 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattagtc aagtccacaa tcttgtgtaa aagttcaacc
     1381 tcat
//
LOCUS       DASHWW010000230         1119 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.189, whole genome shotgun sequence.
ACCESSION   DASHWW010000230 DASHWW010000000
VERSION     DASHWW010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.189"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            1..189
                     /locus_tag="U2R64_003053"
     CDS             1..189
                     /locus_tag="U2R64_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8919768.1"
                     /translation="MAMTISMVVSLYEYPTFATSGFSLVFFLLLGGLLWFIPVALCAA
                     EMATVKGWEKGVSQTKRY"
     gene            584..1057
                     /gene="dfrF"
                     /locus_tag="U2R64_003054"
     CDS             584..1057
                     /gene="dfrF"
                     /locus_tag="U2R64_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HEM8919769.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
BASE COUNT          382 a          140 c          245 g          352 t
ORIGIN      
        1 ttggctatga ccatctcaat ggtcgtttca ttatatgaat atcccacatt cgcgacctca
       61 ggcttcagct tagtattttt cttgttatta ggcggtttgc tatggtttat ccctgtggca
      121 ttgtgcgcag cagagatggc aacggtgaaa ggatgggaaa aaggtgtttc ccaaacaaaa
      181 agatattaag aaacagccca tgtttacctg cttgcaaaca aaagaatatt gctactagac
      241 taagagatac tacataagtg tgttggtatc tcttttttgt tgccgtgaaa cagcagacta
      301 tttcatttct gcttgattac cttaaaactt attagtctat ggtttgtcaa gggcttgttg
      361 cgtgagaaat gctgaatatc accctttaca aaacataggc tgataagtaa cttttcaaaa
      421 gcagaaaaga aatggcaatg cttataacaa tatgatataa tgcagatgaa gacaaaaaag
      481 gaatttgtcg agctggttag ttcgagataa ttttgagttt gttaagatgt ggtgcacttg
      541 atggaatcac aggtacgaca tcatattatg gaggatgaaa tagatgatag gtttgattgt
      601 tgcgaggtca aagaataatg ttataggcaa gaatggtaat ataccatgga aaataaaggg
      661 agaacaaaag caatttagag agttaacaac gggtaatgtg gttattatgg ggcgaaagtc
      721 ttatgaagaa atcggtcatc cgttgcctaa tagaatgaat attgttgttt ccaccacaac
      781 agagtatcaa ggagataatt tagtttcagt taaatcatta gaagatgcat tattattggc
      841 taaaggacga gatgtataca tatctggtgg atatggacta tttaaggaag ctttgcaaat
      901 agtagataaa atgtatatca cagaagtaga tttaaatatt gaagatggag atacattctt
      961 tccagaattt gatatcaatg attttgaagt tttgataggg gaaacacttg gtgaggaagt
     1021 gaaatatacg agaacatttt atgtaaggaa aaaatgaatt gagtaaattt tggatttagg
     1081 gtgttttcat aaatatattg ctttttatgc atatataaa
//
LOCUS       DASHWW010000231          961 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.198, whole genome shotgun sequence.
ACCESSION   DASHWW010000231 DASHWW010000000
VERSION     DASHWW010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.198"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            245..793
                     /gene="aac(6')"
                     /locus_tag="U2R64_003055"
     CDS             245..793
                     /gene="aac(6')"
                     /locus_tag="U2R64_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEM8919770.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          338 a          142 c          204 g          277 t
ORIGIN      
        1 ggtttttttt aaagcaaaag ataatctata tcatgatgaa caaacagagt tttttcctcc
       61 aattgatggc tttcctgatc tttcctattt tgaataaagt gtttctgtat aattttttta
      121 ttttataagt aagataaata atgaaagaat agagatactg attggtagct aaagattttt
      181 gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac aagggggaag
      241 acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc agctttctga
      301 tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag aagtagaaga
      361 aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt tagtaggatt
      421 tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat tagttgtaga
      481 aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag aaaaagaagt
      541 agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc atggaacaac
      601 gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca tccagaacct
      661 tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag gtgtcttacc
      721 aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta ttcctcgacc
      781 aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga aataagaagg
      841 aatttacgaa aattacttct tgaatttttg tgaaattcca acttatttcc gaagaagcta
      901 cttttggaac accgtgtacc agaggttgtg aaaaagtcgc ttagtttcga gtagtaagaa
      961 a
//
LOCUS       DASHWW010000232          832 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE37976
            SAMN38764601-rid20545603.guided.201, whole genome shotgun sequence.
ACCESSION   DASHWW010000232 DASHWW010000000
VERSION     DASHWW010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764601
            Sequence Read Archive: SRR27176721
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024131.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024131.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 05:25:36
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,055
            CDSs (total)                      :: 2,984
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 71
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 31 of 72
            Pseudo Genes (incomplete)         :: 33 of 72
            Pseudo Genes (internal stop)      :: 21 of 72
            Pseudo Genes (multiple problems)  :: 12 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764601-rid20545603.guided.201"
                     /strain="VRE37976"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          262 a          154 c          124 g          292 t
ORIGIN      
        1 ctctcatagt cggcatatac atattaaaga gtaaaaagat accccaaatc cctattagta
       61 acaagatcag ttctttgtta ttcgttattt ttctattatg tttgttcatt tttatactcc
      121 ttcttatatt tcctaataga gtataacata gctttaagca ttacttaaag ataacttaaa
      181 agttatcttt taaatactta attgttaaat accttatttg atgcaaaaga aatctacgat
      241 agtcaacaaa aaaattttca ttatatccag aaaaattttt cttagttaag gacctatgga
      301 ttgcagtaat gcagaattcg tcgaataaac tgccaaagac atacaatcat attgctttta
      361 aaattgacga acaagatata gattcgtttg tctcaaaaat ccaaatgtta ggtttaactg
      421 tcgaaccagg acgttctcgt gtgaaaggcg aggcttcttc aatttacttt tacgactatg
      481 ataatcacct cttcgagtta cataccggta ctctccagga acgtttaaaa tcctacaatt
      541 ccactacctg agactagtaa tgactagtct ctttttatgg cctctgatcc ccccattgag
      601 cgaatactaa tagggcttcg aattgatctg ttcaatcttt aagcaatatc cctcaaatga
      661 gtttggaaag tttagtgatt catcacaaat acttaaatac atgtagttat atatagattg
      721 aggttcttgt gagcgtatgc tcgtgtgggt tcaaatccca tcgtctgcat ccatctttcc
      781 aaaacaagcg gctaggacat ttttgtctca gccgcttgtt ttctagttta tt
//
